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細胞番号 : 細胞名
HPS0063 : 201B7  update : 2024/10/25
細胞特性(Comment:英)Human iPS cell line. HPS0002, HPS0063, HPS0076, HPS0296, HPS0326, HPS3668, HPS4290, HPS4291, HPS4292 were derived from the same person. Cryopreserved by vitrification method. Feeder-less 201B7 is also available as HPS4290 : 201B7-Ff.
細胞特性(日)ヒト人工多能性幹(iPS)細胞株。HPS0002, HPS0063, HPS0076, HPS0296, HPS0326, HPS3668, HPS4290, HPS4291, HPS4292は同一人由来。レトロウイルスベクターにより4因子(Oct3/4,Sox2,Klf4,c-Myc)を導入。前提供番号HPS0001 。ガラス化法(Vitrification法)保存。フィーダーレス化した細胞 (HPS4290 : 201B7-Ff) を提供中。
細胞特性(寄託者記述:英)
細胞特性(寄託者記述:日)
使用条件(英)1) In relation to the for-profit organizations, please contact iPS Academia Japan, Inc., prior to the utilization of iPS cells. 2) Attach Appendix (non-for-profit) or Appendix (for-profit) to MTA (C-0007 or C-0007p) .
使用条件(日)1) 非営利機関以外の利用者は事前にiPSアカデミアジャパン株式会社 から確認書を得ること。2) 別紙1 (非営利) または別紙1 (営利) を提供同意書 (C-0003またはC-0003p) に添付すること。
備考(英)
備考(日)
提供申込書類(英) Order Form(C-0042.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)  
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
提供申込書類(日) 依頼書C-0041.pdf   同意書(非営利学術目的)C-0003.pdf   同意書(営利目的)C-0003p.pdf  
提供同意書は、使用機関の種類や目的に応じて、非営利学術目的 (C-XXXX) と営利目的 (C-XXXXp) の2種類があります。該当する提供同意書をご使用ください(詳細)。特許等の取得及び商業利用等は事前に必ず cellbank.brc@riken.jp までご連絡ください。
提供手数料 手数料とお支払いについてはこちらをご覧ください。
細胞基本情報 寄託者 https://www.cira.kyoto-u.ac.jp/
樹立者 Yamanaka, Shinya
寄託日 2011
別名 HPS0001 201B7
動物種 _human < Mammals
属名 Homo
種名 sapiens
人種 Caucasian
性別 Female
36 years
採取組織 skin
細胞分類 iPS
遺伝子改変 recombinant
外来遺伝子 pMXs-Oct3/4, -Sox2, -Klf4, -c-Myc, pLenti6/UbC/V5-DEST, mouse Slc7a1
細胞寿命 infinite
細胞形態 ES-like
Cellosaurus(Expasy) CVCL_A324
細胞培養・検査情報
寄託時情報
ロット情報
培地・試薬情報 培地・試薬一覧はこちらをご覧ください。
培養形態 Adherent cells
培地 Primate ES Cell Medium + 4ng/ml human basic FGF
抗生物質 Free
継代方法 0.25% Trypsin + 0.1% collagenase type IV + 20% KSR + 1mM CaCl2 + PBS(-)
培養容器のコーティング 0.1% gelatin coated dish
継代密度 1 : 3 split
継代・培地交換頻度 Subculture : once/4-6 days, Medium Renewal : every day
培養最適温度 37 ℃
二酸化炭素濃度 5 %
フィーダー細胞 SNL 76/7
フィーダー細胞の処理方法 X-rays 5000R (or MMC)
フィーダー細胞の播種数 1.5-2.5 x 10 6 cells/100 mm dish
凍結培地 DAP213 : Medium + 2M DMSO + 1M Acetamide + 3M Propyleneglycol
凍結方法 Vitrification
マイコプラズマ/アコレプラズマ (-)
染色体検査 46,XX[20] at passage No. 30
個体識別検査 OK
画像情報
寄託時情報
ロット情報
その他の細胞情報 寄託時情報ロット情報
SDS_DAP(MEM)_Japanese.pdf
文献情報 Reference(英) 2件
Reference(日) 0件
利用者成果(英) 320件
利用者成果(日) 2件

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Reference(英)
20937  Tsujimoto H, Katagiri N, Ijiri Y, Sasaki B, Kobayashi Y, Mima A, Ryosaka M, Furuyama K, Kawaguchi Y, Osafune K.  In vitro methods to ensure absence of residual undifferentiated human induced pluripotent stem cells intermingled in induced nephron progenitor cells.  PLoS One  2022  17(11)6:e0275600  PubMed ID: 36378656   DOI: 10.1371/journal.pone.0275600
3675  Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, Yamanaka S.  Induction of pluripotent stem cells from adult human fibroblasts by defined factors.  Cell  2007  131(5):861-72  PubMed ID: 18035408   DOI: 10.1016/j.cell.2007.11.019

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Reference(日)

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利用者成果(英)
22203  Quantitative Proteomics for the Development and Manufacturing of Human-Induced Pluripotent Stem Cell-Derived Neural Stem Cells Using Data-Independent Acquisition Mass Spectrometry  Quantitative Proteomics for the Development and Manufacturing of Human-Induced Pluripotent Stem Cell-Derived Neural Stem Cells Using Data-Independent Acquisition Mass Spectrometry  J Proteome Res  203  22(6):1843-1854  PubMed ID: 37097202   DOI: 10.1021/acs.jproteome.2c00841
21544  Ueki M, Suzuki T, Kato Y.  Large-scale cultivation of human iPS cells in bioreactor with reciprocal mixing.  J Biosci Bioeng  2024    PubMed ID: 38185598   DOI: 10.1016/j.jbiosc.2023.12.008
21546  Kuroda T, Yasuda S, Matsuyama S, Miura T, Sawada R, Matsuyama A, Yamamoto Y, Morioka MS, Kawaji H, Kasukawa T, Itoh M, Akutsu H, Kawai J, Sato Y.  ROR2 expression predicts human induced pluripotent stem cell differentiation into neural stem/progenitor cells and GABAergic neurons.  Sci Rep  2024  14(1):690  PubMed ID: 38184695   DOI: 10.1038/s41598-023-51082-4
21552  Kurabi A, Dewan K, Kerschner JE, Leichtle A, Li JD, Santa Maria PL, Preciado D.  PANEL 3: Otitis media animal models, cell culture, tissue regeneration & pathophysiology.  Int J Pediatr Otorhinolaryngol  2024  176:111814  PubMed ID: 38101097   DOI: 10.1016/j.ijporl.2023.111814
21572  Shaji M, Tamada A, Fujimoto K, Muguruma K, Karsten SL, Yokokawa R.  Deciphering potential vascularization factors of on-chip co-cultured hiPSC-derived cerebral organoids.  Lab Chip  2024    PubMed ID: 38284292   DOI: 10.1039/d3lc00930k
21622  Shiraishi T, Bono K, Hiraki H, Manome Y, Oka H, Iguchi Y, Okano HJ.  The impact of VPS35 D620N mutation on alternative autophagy and its reversal by estrogen in Parkinson's disease.  Cell Mol Life Sci  2024  81(1):103  PubMed ID: 38409392   DOI: 10.1007/s00018-024-05123-4
21668  Homma H, Yoshioka Y, Fujita K, Shirai S, Hama Y, Komano H, Saito Y, Yabe I, Okano H, Sasaki H, Tanaka H, Okazawa H.  Dynamic molecular network analysis of iPSC-Purkinje cells differentiation delineates roles of ISG15 in SCA1 at the earliest stage.  Commun Biol  2024  7(1):413  PubMed ID: 38594382   DOI: 10.1038/s42003-024-06066-z
21767  Intoh A, Watanabe-Susaki K, Kato T, Kiritani H, Kurisaki A.  EPHA2 is a novel cell surface marker of OCT4-positive undifferentiated cells during the differentiation of mouse and human pluripotent stem cells.  Stem Cells Transl Med  2024    PubMed ID: 38811016   DOI: 10.1093/stcltm/szae036
21816  Sekine M, Fujiwara M, Okamoto K, Ichida K, Nagata K, Hille R, Nishino T.  Significance and Amplification Methods of the Purine Salvage Pathway in Human Brain Cells.  J Biol Chem  2024    PubMed ID: 38960035   DOI: 10.1016/j.jbc.2024.107524
21909  Yasuda S, Bando K, Henry MP, Libertini S, Watanabe T, Bando H, Chen C, Fujimori K, Harada K, Kuroda T, Lemmens M, Marginean D, Moss D, Pereira Mouriès L, Nicholas NS, Smart MJK, Terai O, Sato Y.  Detection of residual pluripotent stem cells in cell therapy products utilizing droplet digital PCR: an international multisite evaluation study.  Stem Cells Transl Med  2024    PubMed ID: 39120125   DOI: 10.1093/stcltm/szae058
21988  Saegusa C, Mutai H, Saeki T, Matsuzaki S, Mizukoshi A, Kitajiri SI, Matsunaga T, Hosoya M, Okano H, Fujioka M.  Generation of four induced pluripotent stem cell lines (KEIUi004-A, KEIUi005-A, KEIUi006-A, and KEIUi007-A) from patients with sensorineural hearing loss with mutation in EYA4 gene  Stem Cell Res  2024  79:103489  PubMed ID: 39002249   DOI: 10.1016/j.scr.2024.103489
21990  Maruyama K, Miyazaki S, Kobayashi R, Hikita H, Tsubone T, Ohnuma K.  The migration pattern of cells during the mesoderm and endoderm differentiation from human pluripotent stem cells  In Vitro Cell Dev Biol Anim  2024  60(5):535-543  PubMed ID: 38656570   DOI: 10.1007/s11626-024-00904-4
22007  Masano Y, Saegusa C, Ishikawa M, Matsunaga T, Okano H, Fujioka M.  Generation of an induced pluripotent stem cell line (KEIUi008-A) from a hearing loss patient with an A1555G mutation in mitochondrial DNA.  Stem Cell Res  2024  78:103452  PubMed ID: 38815527   DOI: 10.1016/j.scr.2024.103452
22011  Watanabe T, Yasuda S, Kusakawa S, Kuroda T, Furukawa H, Futamura M, Shimizu S, Morishita A, Hata S, Koeda A, Komatsu K, Sato Y.  Multisite studies for optimization of a highly efficient culture assay used for in vitro detection of residual undifferentiated human pluripotent stem cells intermingled in cell therapy products.  Regen Ther  2024  26:315-323  PubMed ID: 38983832   DOI: 10.1016/j.reth.2024.06.007
22138  Howard L, Ishikawa Y, Katayama T, Park SJ, Hill MJ, Blake DJ, Nishida K, Hayashi R, Quantock AJ.  Single-cell transcriptomics reveals the molecular basis of human iPS cell differentiation into ectodermal ocular lineages.  Commun Biol  2024  7(1):1495  PubMed ID: 39532995   DOI: 10.1038/s42003-024-07130-4
22140  Horikawa A, Michiue T.  Controlling spheroid attachment improves pancreatic beta cell differentiation from human iPS cells.  In Vitro Cell Dev Biol Anim  2024    PubMed ID: 39546193   DOI: 10.1007/s11626-024-00991-3
22171  Matsuo-Takasaki M, Kambayashi S, Hemmi Y, Wakabayashi T, Shimizu T, An Y, Ito H, Takeuchi K, Ibuki M, Kawashima T, Masayasu R, Suzuki M, Kawai Y, Umekage M, Kato TM, Noguchi M, Nakade K, Nakamura Y, Nakaishi T, Nishishita N, Tsukahara M, Hayashi Y.  Complete suspension culture of human induced pluripotent stem cells supplemented with suppressors of spontaneous differentiation.  Elife  2024  12  PubMed ID: 39529479   DOI: 10.7554/eLife.89724
22196  Kikuchi T, Matsuura K, Shimizu T.  Low-adhesion culture selection for human iPS cell-derived cardiomyocytes  Sci Rep  2024  14(1):11081  PubMed ID: 38744867   DOI: 10.1038/s41598-024-60765-5
19655  Mu A, Hira A, Mori M, Okamoto Y, Takata M.  Fanconi anemia and Aldehyde Degradation Deficiency Syndrome: Metabolism and DNA repair protect the genome and hematopoiesis from endogenous DNA damage  DNA Repair (Amst)  2023  130:103546  PubMed ID: 37572579   DOI: 10.1016/j.dnarep.2023.103546
19705  Soo-jeong Park, Jeong-Woo Choi  Nanoscale Diesel-Exhaust Particulate Matter (DPM) Impairs Synaptic Plasticity of Human iPSCs-Derived Cerebral Organoids  BioChip Journal  2023  17:BioChip Journal    DOI: 10.1007/s13206-023-00107-1
19717  Akaba Y, Takahashi S, Suzuki K, Kosaki K, Tsujimura K.  miR-514a promotes neuronal development in human iPSC-derived neurons  Front Cell Dev Biol  2023  11:1096463  PubMed ID: 36824367   DOI: 10.3389/fcell.2023.1096463
19750  Kitao M, Hayashi R, Nomi K, Kobayashi R, Katayama T, Takayanagi H, Oguchi A, Murakawa Y, Nishida K.  Identification of BST2 as a conjunctival epithelial stem/progenitor cell marker  iScience  2023  26(7):107016  PubMed ID: 37389178   DOI: 10.1016/j.isci.2023.107016
19819  Zhang D, Eguchi N, Okazaki S, Sora I, Hishimoto A.  Telencephalon Organoids Derived from an Individual with ADHD Show Altered Neurodevelopment of Early Cortical Layer Structure  Stem Cell Rev Rep  2023  19(5):1482-1491  PubMed ID: 36872412   DOI: 10.1007/s12015-023-10519-z
19841  Yoshioka Y, Taniguchi JB, Homma H, Tamura T, Fujita K, Inotsume M, Tagawa K, Misawa K, Matsumoto N, Nakagawa M, Inoue H, Tanaka H, Okazawa H.  AAV-mediated editing of PMP22 rescues Charcot-Marie-Tooth disease type 1A features in patient-derived iPS Schwann cells  Commun Med (Lond)   2023  3(1):170  PubMed ID: 38017287   DOI: 10.1038/s43856-023-00400-y
19859  Lázaro J, Costanzo M, Sanaki-Matsumiya M, Girardot C, Hayashi M, Hayashi K, Diecke S, Hildebrandt TB, Lazzari G, Wu J, Petkov S, Behr R, Trivedi V, Matsuda M, Ebisuya M.  A stem cell zoo uncovers intracellular scaling of developmental tempo across mammals  Cell Stem Cell  2023  30(7):938-949  PubMed ID: 37343565   DOI: 10.1016/j.stem.2023.05.014
19862  Takayama Y, Akagi Y, Kida YS.  Deciphering the Molecular Mechanisms of Autonomic Nervous System Neuron Induction through Integrative Bioinformatics Analysis  Int J Mol Sci  2023  24(10):9053  PubMed ID: 37240399   DOI: 10.3390/ijms24109053
19938  Liu L, Yang J, Otani Y, Shiga T, Yamaguchi A, Oda Y, Hattori M, Goto T, Ishibashi S, Kawashima-Sonoyama Y, Ishihara T, Matsuzaki Y, Akamatsu W, Fujitani M, Taketani T.  MELAS-Derived Neurons Functionally Improve by Mitochondrial Transfer from Highly Purified Mesenchymal Stem Cells (REC)  Int J Mol Sci  2023  24(24):17186  PubMed ID: 38139018   DOI: 10.3390/ijms242417186
20931  Shoji M, Kuzuhara T.  Imaging Analysis of Neurotrophic Effects by CCN2 Protein in Neuronal Precursor Cells Derived from Human-Induced Pluripotent Stem Cells.  Methods Mol Biol  2023  2582:269-280  PubMed ID: 36370356   DOI: 10.1007/978-1-0716-2744-0_18
21010  Shimada M, Tokumiya T, Miyake T, Tsukada K, Kanzaki N, Yanagihara H, Kobayashi J, Matsumoto Y.  Implication of E3 ligase RAD18 in UV-induced mutagenesis in human induced pluripotent stem cells and neuronal progenitor cells.  J Radiat Res  2023    PubMed ID: 36634340   DOI: 10.1093/jrr/rrac099
21070  Tanaka Y, Furuhata E, Maeda S, Kishima M, Suzuki H, Suzuki T.  A dataset of definitive endoderm and hepatocyte differentiations from human induced pluripotent stem cells.  Sci Data  2023  10(1):93  PubMed ID: 36788249   DOI: 10.1038/s41597-023-02001-9
21160  Yue F, Era T, Yamaguchi T, Kosho T.  Pathophysiological Investigation of Skeletal Deformities of Musculocontractural Ehlers-Danlos Syndrome Using Induced Pluripotent Stem Cells.  Genes (Basel)  2023  14(3)  PubMed ID: 36981001   DOI: 10.3390/genes14030730
21189  Matsumoto N, Yamanaka S, Morimoto K, Matsui K, Nishimura S, Kinoshita Y, Inage Y, Fujimori K, Kuroda T, Saito Y, Takamura T, Fujimoto T, Tajiri S, Matsumoto K, Inoue M, Kobayashi E, Yokoo T.  Evaluation of the ability of human induced nephron progenitor cells to form chimeric renal organoids using mouse embryonic renal progenitor cells.  Biochem Biophys Res Commun  2023  662:18-25  PubMed ID: 37094429   DOI: 10.1016/j.bbrc.2023.04.052
21192  Otsuka S, Qin XY, Wang W, Ito T, Nansai H, Abe K, Fujibuchi W, Nakao Y, Sone H.  iGEM as a human iPS cell-based global epigenetic modulation detection assay provides throughput characterization of chemicals affecting DNA methylation.  Sci Rep  2023  13(1):6663  PubMed ID: 37095195   DOI: 10.1038/s41598-023-33729-4
21260  Taga S, Suga H, Nakano T, Kuwahara A, Inoshita N, Kodani Y, Nagasaki H, Sato Y, Tsumura Y, Sakakibara M, Soen M, Miwata T, Ozaki H, Kano M, Watari K, Ikeda A, Yamanaka M, Takahashi Y, Kitamoto S, Kawaguchi Y, Miyata T, Kobayashi T, Sugiyama M, Onoue T, Yasuda Y, Hagiwara D, Iwama S, Tomigahara Y, Kimura T, Arima H.  Generation and purification of ACTH-secreting hPSC-derived pituitary cells for effective transplantation.  Stem Cell Reports  2023    PubMed ID: 37295423   DOI: 10.1016/j.stemcr.2023.05.002
21311  Kaneko H, Kaitsuka T, Tomizawa K.  Artificial induction of circadian rhythm by combining exogenous BMAL1 expression and polycomb repressive complex 2 inhibition in human induced pluripotent stem cells.  Cell Mol Life Sci  2023  80(8):200  PubMed ID: 37421441   DOI: 10.1007/s00018-023-04847-z
21342  Oiwa K, Watanabe S, Onodera K, Iguchi Y, Kinoshita Y, Komine O, Sobue A, Okada Y, Katsuno M, Yamanaka K.  Monomerization of TDP-43 is a key determinant for inducing TDP-43 pathology in amyotrophic lateral sclerosis.  Sci Adv  2023  9(31):eadf6895  PubMed ID: 37540751   DOI: 10.1126/sciadv.adf6895
21348  Katsura M, Urade Y, Nansai H, Kobayashi M, Taguchi A, Ishikawa Y, Ito T, Fukunaga H, Tozawa H, Chikaoka Y, Nakaki R, Echigo A, Kohro T, Sone H, Wada Y.  Low-dose radiation induces unstable gene expression in developing human iPSC-derived retinal ganglion organoids.  Sci Rep  2023  13(1):12888  PubMed ID: 37558727   DOI: 10.1038/s41598-023-40051-6
21395  Tanaka Y, Kadota S, Zhao J, Kobayashi H, Okano S, Izumi M, Honda Y, Ichimura H, Shiba N, Uemura T, Wada Y, Chuma S, Nakada T, Tohyama S, Fukuda K, Yamada M, Seto T, Kuwahara K, Shiba Y.  Mature human induced pluripotent stem cell-derived cardiomyocytes promote angiogenesis through alpha-B crystallin.  Stem Cell Res Ther  2023  14(1):240  PubMed ID: 37679796   DOI: 10.1186/s13287-023-03468-4
21405  Murata H, Phoo MTZ, Ochi T, Tomonobu N, Yamamoto KI, Kinoshita R, Miyazaki I, Nishibori M, Asanuma M, Sakaguchi M.  Phosphorylated SARM1 is involved in the pathological process of rotenone-induced neurodegeneration.  J Biochem  2023    PubMed ID: 37725528   DOI: 10.1093/jb/mvad068
21439  Terada E, Bamba Y, Takagaki M, Kawabata S, Tachi T, Nakamura H, Nishida T, Kishima H.  Silicate Microfiber Scaffolds Support the Formation and Expansion of the Cortical Neuronal Layer of Cerebral Organoids With a Sheet-Like Configuration.  Stem Cells Transl Med  2023    PubMed ID: 37843388   DOI: 10.1093/stcltm/szad066
21488  Akagi Y, Takayama Y, Nihashi Y, Yamashita A, Yoshida R, Miyamoto Y, Kida YS.  Functional engineering of human iPSC-derived parasympathetic neurons enhances responsiveness to gastrointestinal hormones.  FEBS Open Bio  2023    PubMed ID: 38013211   DOI: 10.1002/2211-5463.13741
21532  Tomizawa M, Shinozaki F, Mikata T, Tanno H, Shigeta M.  Lactate promotes survival and hepatocyte differentiation of human induced pluripotent stem cells in a medium without glucose and supplemented with galactose.  Biomed Rep  2023  19(6):90  PubMed ID: 37901872   DOI: 10.3892/br.2023.1672
21924  Murata H, Yasui Y, Oiso K, Ochi T, Tomonobu N, Yamamoto KI, Kinoshita R, Sakaguchi M.  STAT1/3 signaling suppresses axon degeneration and neuronal cell death through regulation of NAD+-biosynthetic and consuming enzymes  Cell Signal  2023  108:110717.  PubMed ID: 37187216   DOI: 10.1016/j.cellsig.2023.110717
22199  Nakamura R, Nonaka R, Oyama G, Jo T, Kamo H, Nuermaimaiti M, Akamatsu W, Ishikawa KI, Hattori N.  A defined method for differentiating human iPSCs into midbrain dopaminergic progenitors that safely restore motor deficits in Parkinson's disease  Front Neurosci  2023  17:1202027  PubMed ID: 37502682   DOI: 10.3389/fnins.2023.1202027
22202  Uno N, Satofuka H, Miyamoto H, Honma K, Suzuki T, Yamazaki K, Ito R, Moriwaki T, Hamamichi S, Tomizuka K, Oshimura M, Kazuki Y.  Treatment of CHO cells with Taxol and reversine improves micronucleation and microcell-mediated chromosome transfer efficiency  Mol Ther Nucleic Acids  2023  33:391-403  PubMed ID: 37547291   DOI: 10.1016/j.omtn.2023.07.002
17534  Miyake N, Nagai T, Suga H, Osuka S, Kasai T, Sakakibara M, Soen M, Ozaki H, Miwata T, Asano T, Kano M, Muraoka A, Nakanishi N, Nakamura T, Goto M, Yasuda Y, Kawaguchi Y, Miyata T, Kobayashi T, Sugiyama M, Onoue T, Hagiwara D, Iwama S, Iwase A, Inoshita N, Arima H, Kajiyama H.  Functional Lactotrophs in Induced Adenohypophysis Differentiated From Human iPS Cells  Endocrinology  2022  163(3):bqac004  PubMed ID: 35085394   DOI: 10.1210/endocr/bqac004
17538  Kodani Y, Kawata M, Suga H, Kasai T, Ozone C, Sakakibara M, Kuwahara A, Taga S, Arima H, Kameyama T, Saito K, Nakashima A, Nagasaki H.  EpCAM Is a Surface Marker for Enriching Anterior Pituitary Cells From Human Hypothalamic-Pituitary Organoids  Front Endocrinol (Lausanne)  2022  13:941166  PubMed ID: 35903276   DOI: 10.3389/fendo.2022.941166
19243  Shimizu K, Kassai H, Kamei Y, Yamamoto K, Nagashima T, Maekawa T, Akiyama H, Honda H.  Alignment of Skeletal Muscle Cells Facilitates Acetylcholine Receptor Clustering and Neuromuscular Junction Formation with Co-Cultured Human iPSC-Derived Motor Neurons  Cells  2022  11(23):3760  PubMed ID: 36497020   DOI: 10.3390/cells11233760
20537  Nakatani E, Okajima R, Ohnuma K.  Slow diffusion on the monolayer culture enhances auto/paracrine effects of Noggin in differentiation of human iPS cells induced by BMP.  Biochem Biophys Rep  2022  29:101195  PubMed ID: 35005256   DOI: 10.1016/j.bbrep.2021.101195
20566  Kanno S, Okubo Y, Kageyama T, Yan L, Kitajima S, Fukuda J.  Establishment of a developmental toxicity assay based on human iPSC reporter to detect FGF signal disruption.  iScience  2022  25(2):103770  PubMed ID: 35146387   DOI: 10.1016/j.isci.2022.103770
20530  Kanno S, Okubo Y, Kageyama T, Yan L, Fukuda J.  Integrated fibroblast growth factor signal disruptions in human iPS cells for prediction of teratogenic toxicity of chemicals.  J Biosci Bioeng  2022    PubMed ID: 35034848   DOI: 10.1016/j.jbiosc.2021.12.006
20579  Uno N, Takata S, Komoto S, Miyamoto H, Nakayama Y, Osaki M, Mayuzumi R, Miyazaki N, Hando C, Abe S, Sakuma T, Yamamoto T, Suzuki T, Nakajima Y, Oshimura M, Tomizuka K, Kazuki Y.  Panel of human cell lines with human/mouse artificial chromosomes.  Sci Rep  2022  12(1):3009  PubMed ID: 35194085   DOI: 10.1038/s41598-022-06814-3
16355  Takeshi Tada, Hiroe Ohnishi, Norio Yamamoto, Fumihiko Kuwata, Yasuyuki Hayashi, Hideaki Okuyama, Tsunetaro Morino, Yoshiyuki Kasai, Hiromi Kojima, Koichi Omori  Transplantation of a human induced pluripotent stem cell-derived airway epithelial cell sheet into the middle ear of rats  Regen Ther  2022  19:77-87  PubMed ID: 35097166   DOI: 10.1016/j.reth.2022.01.001
16361  Takahashi H, Oikawa F, Takeda N, Shimizu T.  Contraction Control of Aligned Myofiber Sheet Tissue by Parallel Oriented iPS Cell-derived Neurons  Tissue Eng Part A  2022  Jan 21  PubMed ID: 35057641   DOI: 10.1089/ten.TEA.2021.0202
20587  Uehara K, Koyanagi-Aoi M, Koide T, Itoh T, Aoi T.  Epithelial-derived factors induce muscularis mucosa of human induced pluripotent stem cell-derived gastric organoids.  Stem Cell Reports  2022    PubMed ID: 35245440   DOI: 10.1016/j.stemcr.2022.02.002
16439  Otsuka Y, Imamura K, Oishi A, Kondo T, Suga M, Yada Y, Shibukawa R, Okanishi Y, Sagara Y, Tsukita K, Tsujikawa A, Inoue H.  One-step induction of photoreceptor-like cells from human iPSCs by delivering transcription factors  iScience   2022  25(4):103987.  PubMed ID: 35330684   DOI: 10.1016/j.isci.2022.103987
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11391  Iwasawa C, Kuzumaki N, Suda Y, Kagawa R, Oka Y, Hattori N, Okano H, Narita M.  Reduced expression of somatostatin in GABAergic interneurons derived from induced pluripotent stem cells of patients with parkin mutations.  Mol Brain  2019    PubMed ID: 30658665   DOI: 10.1186/s13041-019-0426-7
11424  Dion J, Minoshima F, Saito S, Kiyoi K, Hasehira K, Tateno H.  Photoactivable elimination of tumorigenic human induced pluripotent stem cells using a lectin-doxorubicin prodrug conjugate.  Chembiochem  2019    PubMed ID: 30737871   DOI: 10.1002/cbic.201900086
11468  Kono K, Sawada R, Kuroda T, Yasuda S, Matsuyama S, Matsuyama A, Mizuguchi H, Sato Y.  Development of selective cytotoxic viral vectors for concentration of undifferentiated cells in cardiomyocytes derived from human induced pluripotent stem cells.  Sci Rep  2019    PubMed ID: 30842516   DOI: 10.1038/s41598-018-36848-5
4572  Kuroda T, Yasuda S, Tachi S, Matsuyama S, Kusakawa S, Tano K, Miura T, Matsuyama A, Sato Y.  SALL3 expression balance underlies lineage biases in human induced pluripotent stem cell differentiation.  Nat Commun  2019  10(1):2175  PubMed ID: 31092818   DOI: 10.1038/s41467-019-09511-4
11516  Matsushita S, Kajiwara T, Mizumoto H.  Expansion and differentiation of human iPS cells in a three-dimensional culture using hollow fibers and separation of the specific population by magnetic-activated cell sorting.  J. Biosci. Bioeng.  2019    PubMed ID: 30982708   DOI: 10.1016/j.jbiosc.2019.03.014
11531  Kuzumaki N, Suda Y, Iwasawa C, Narita M, Sone T, Watanabe M, Maekawa A, Matsumoto T, Akamatsu W, Igarashi K, Tamura H, Takeshima H, Tawfik VL, Ushijima T, Hattori N, Okano H, Narita M.  Cell-specific overexpression of COMT in dopaminergic neurons of Parkinson's disease.  Brain  2019    PubMed ID: 31135049   DOI: 10.1093/brain/awz084
11576  Komatsu Y, Takeuchi D, Tokunaga T, Sakurai H, Makino A, Honda T, Ikeda Y, Tomonaga K.  RNA Virus-Based Episomal Vector with a Fail-Safe Switch Facilitating Efficient Genetic Modification and Differentiation of iPSCs.  Mol Ther Methods Clin Dev  2019  14:47-55  PubMed ID: 31309127   DOI: 10.1016/j.omtm.2019.05.010
11653  Nao Yamaoka, Kazunori Shimizu, Yu Imaizumi, Takuji Ito, Yohei Okada, Hiroyuki Honda  Open-Chamber Co-Culture Microdevices for Single-Cell Analysis of Skeletal Muscle Myotubes and Motor Neurons with Neuromuscular Junctions  BioChip Journal  2019      DOI: 10.1007/s13206-018-3202-3
11679  Sachiko Sekiya, Tetsutaro Kikuchi, Tatsuya Shimizu  Perfusion culture maintained with an air-liquid interface to stimulate epithelial cell organization in renal organoids in vitro  BMC Biomedical Engineering  2019  1:15  PubMed ID: 32903332   DOI: 10.1186/s42490-019-0017-9
11788  Shoji M, Ueda M, Nishioka M, Minato H, Seki M, Harada K, Kubo M, Fukuyama Y, Suzuki Y, Aoyama E, Takigawa M, Kuzuhara T.  Jiadifenolide induces the expression of cellular communication network factor (CCN) genes, and CCN2 exhibits neurotrophic activity in neuronal precursor cells derived from human induced pluripotent stem cells.  Biochem. Biophys. Res. Commun.  2019    PubMed ID: 31506177   DOI: 10.1016/j.bbrc.2019.09.003
11798  Sugawara Y, Hamada K, Yamada Y, Kumai J, Kanagawa M, Kobayashi K, Toda T, Negishi Y, Katagiri F, Hozumi K, Nomizu M, Kikkawa Y.  Characterization of dystroglycan binding in adhesion of human induced pluripotent stem cells to laminin-511 E8 fragment.  Sci Rep  2019    PubMed ID: 31506597   DOI: 10.1038/s41598-019-49669-x
11875  Shimada M, Tsukada K, Kagawa N, Matsumoto Y.  Reprogramming and differentiation-dependent transcriptional alteration of DNA damage response and apoptosis genes in human induced pluripotent stem cells.  J. Radiat. Res.  2019    PubMed ID: 31665364   DOI: 10.1093/jrr/rrz057
10103  Tomoko Miyake, Mikio Shimada, Yoshihisa Matsumoto, Akitoshi Okino  DNA Damage Response After Ionizing Radiation Exposure in Skin Keratinocytes Derived From Human-Induced Pluripotent Stem Cells  Int J Radiat Oncol Biol Phys .  2019  105(1):193-205  PubMed ID: 31085283   DOI: 10.1016/j.ijrobp.2019.05.006
11968  Hayakawa K, Nishitani K, Tanaka S.  Kynurenine, 3-OH-kynurenine, and anthranilate are nutrient metabolites that alter H3K4 trimethylation and H2AS40 O-GlcNAcylation at hypothalamus-related loci.  Sci Rep  2019    PubMed ID: 31875008   DOI: 10.1038/s41598-019-56341-x
12138  Takayuki Nakamura, MD, Shinichi Mizuno, MD PhD, Hidetoshi Ozawa, Yoshitaka Yamasaki, MD, Shuki Oya, MD, Satoshi Morishige, MD, Kazutoshi Aoyama, MD PhD, Maki Ymaguchi, MD PhD, Ritsuko Seki, PhD, Fumihiko Mouri, MD PhD, Koichi Osaki, MD, Koji Nagafuji, MD PhD  A Functional Analysis of SNP on Anthracycline-Induced Cardiotoxicity in a Uniform Genetic Background Using CRISPR/Cas9 Mediated Single-Base-Edited iPSCs  Blood   2019      DOI: 10.1182/blood-2019-123932
12141  Ayako Oyane, Hiroko Araki, Maki Nakamura, Yasuhiko Aiki, Kumiko Higuchi, Alexander Pyatenko, Masaki Adachi and Yuzuru Ito  Controlled release of basic fibroblast growth factor from a water-floatable polyethylene nonwoven fabric sheet for maintenance culture of iPSCs  RSC Adv  2019  10(1):95-104  PubMed ID: 35492512   DOI: 10.1039/C9RA06906B
12334  Wei H, Wang C, Guo R, Takahashi K, Naruse K.  Development of a model of ischemic heart disease using cardiomyocytes differentiated from human induced pluripotent stem cells  Biochem Biophys Res Commun  2019  520(3):600-605  PubMed ID: 31623826   DOI: 10.1016/j.bbrc.2019.09.119
12355  Okuyama H, Ohnishi H, Nakamura R, Yamashita M, Kishimoto Y, Tateya I, Suehiro A, Gotoh S, Takezawa T, Nakamura T, Omori K.  Transplantation of multiciliated airway cells derived from human iPS cells using an artificial tracheal patch into rat trachea  J Tissue Eng Regen Med  2019  13(6):1019-1030  PubMed ID: 30809958   DOI: 10.1002/term.2849
12356  Tsuruyama S, Matsuura K, Sakaguchi K, Shimizu T.  Pulsatile tubular cardiac tissues fabricated by wrapping human iPS cells-derived cardiomyocyte sheets  Regen Ther  2019  11:297-305  PubMed ID: 31667209   DOI: 10.1016/j.reth.2019.09.001
12357  Inui A, Sekine H, Sano K, Dobashi I, Yoshida A, Matsuura K, Kobayashi E, Ono M, Shimizu T.  Generation of a large-scale vascular bed for the in vitro creation of three-dimensional cardiac tissue  Regen Ther  2019  11:316-323  PubMed ID: 31687425   DOI: 10.1016/j.reth.2019.10.001
12358  Ito E, Miyagawa S, Takeda M, Kawamura A, Harada A, Iseoka H, Yajima S, Sougawa N, Mochizuki-Oda N, Yasuda S, Sato Y, Sawa Y.  Tumorigenicity assay essential for facilitating safety studies of hiPSC-derived cardiomyocytes for clinical application  Sci Rep  2019  9(1):1881  PubMed ID: 30760836   DOI: 10.1038/s41598-018-38325-5
16886  Fujii S, Yoshida S, Inagaki E, Hatou S, Tsubota K, Takahashi M, Shimmura S, Sugita S.  Immunological Properties of Neural Crest Cells Derived from Human Induced Pluripotent Stem Cells  Stem Cells Dev  2019  28(1):28-43  PubMed ID: 30251915   DOI: 10.1089/scd.2018.0058
16889  Nakanishi H, Lee JK, Miwa K, Masuyama K, Yasutake H, Li J, Tomoyama S, Honda Y, Deguchi J, Tsujimoto S, Hidaka K, Miyagawa S, Sawa Y, Komuro I, Sakata Y.  Geometrical Patterning and Constituent Cell Heterogeneity Facilitate Electrical Conduction Disturbances in a Human Induced Pluripotent Stem Cell-Based Platform: An In vitro Disease Model of Atrial Arrhythmias  Front Physiol  2019  10:818  PubMed ID: 31316396   DOI: 10.3389/fphys.2019.00818
7001  Akiyama T, Sato S, Chikazawa-Nohtomi N, Soma A, Kimura H, Wakabayashi S, Ko SBH, Ko MSH.  Efficient differentiation of human pluripotent stem cells into skeletal muscle cells by combining RNA-based MYOD1-expression and POU5F1-silencing.  Sci Rep  2018  8:1189  PubMed ID: 29352121   DOI: 10.1038/s41598-017-19114-y
7003  Yamamoto T, Takenaka C, Yoda Y, Oshima Y, Kagawa K, Miyajima H, Sasaki T, Kawamata S.  Differentiation potential of Pluripotent Stem Cells correlates to the level of CHD7.  Sci Rep  2018  8:241  PubMed ID: 29321579   DOI: 10.1038/s41598-017-18439-y
10630  Matsumura W, Fujita Y, Nakayama C, Shinkuma S, Suzuki S, Nomura T, Abe R, Shimizu H.  Establishment of integration-free induced pluripotent stem cells from human recessive dystrophic epidermolysis bullosa keratinocytes.  J. Dermatol. Sci.  2018  89:263-271  PubMed ID: 29229433   DOI: 10.1016/j.jdermsci.2017.11.017
10758  Suda Y, Kuzumaki N, Sone T, Narita M, Tanaka K, Hamada Y, Iwasawa C, Shibasaki M, Maekawa A, Matsuo M, Akamatsu W, Hattori N, Okano H, Narita M.  Down-regulation of ghrelin receptors on dopaminergic neurons in the substantia nigra contributes to Parkinson's disease-like motor dysfunction.  Mol Brain  2018  11:6  PubMed ID: 29458391   DOI: 10.1186/s13041-018-0349-8
10777  Saito S, Hiemori K, Kiyoi K, Tateno H.  Glycome analysis of extracellular vesicles derived from human induced pluripotent stem cells using lectin microarray.  Sci Rep  2018  8:3997  PubMed ID: 29507392   DOI: 10.1038/s41598-018-22450-2
10813  Sugimoto K, Matsuura T, Nakazono A, Igawa K, Yamada S, Hayashi Y.  Effects of hypoxia inducible factors on pluripotency in human iPS cells.  Microsc. Res. Tech.  2018  81(7):749-754  PubMed ID: 29633433   DOI: 10.1002/jemt.23032
10815  Lee JY, Han SH, Park MH, Baek B, Song IS, Choi MK, Takuwa Y, Ryu H, Kim SH, He X, Schuchman EH, Bae JS, Jin HK.  Neuronal SphK1 acetylates COX2 and contributes to pathogenesis in a model of Alzheimer's Disease.  Nat Commun  2018  9:1479  PubMed ID: 29662056   DOI: 10.1038/s41467-018-03674-2
10821  Tashiro S, Le MNT, Kusama Y, Nakatani E, Suga M, Furue MK, Satoh T, Sugiura S, Kanamori T, Ohnuma K.  High cell density suppresses BMP4-induced differentiation of human pluripotent stem cells to produce macroscopic spatial patterning in a unidirectional perfusion culture chamber.  J. Biosci. Bioeng.  2018  126(3):379-388  PubMed ID: 29681444   DOI: 10.1016/j.jbiosc.2018.03.007
11055  Hayashi Y, Matsumoto J, Kumagai S, Morishita K, Xiang L, Kobori Y, Hori S, Suzuki M, Kanamori T, Hotta K, Sumaru K.  Automated Adherent Cell Elimination by a High-Speed Laser Mediated by a LightResponsive Polymer  Commun Biol  2018  1:218  PubMed ID: 30534610   DOI: 10.1038/s42003-018-0222-4
11135  Arioka Y, Shishido E, Kubo H, Kushima I, Yoshimi A, Kimura H, Ishizuka K, Aleksic B, Maeda T, Ishikawa M, Kuzumaki N, Okano H, Mori D, Ozaki N.  Single-cell trajectory analysis of human homogenous neurons carrying a rare RELN variant.  Transl Psychiatry  2018  8(1):129  PubMed ID: 30022058   DOI: 10.1038/s41398-018-0177-8
11178  Nagashima T, Shimizu K, Matsumoto R, Honda H.  Selective Elimination of Human Induced Pluripotent Stem Cells Using Medium with High Concentration of L-Alanine.  Sci Rep  2018  8(1):12427  PubMed ID: 30127448   DOI: 10.1038/s41598-018-30936-2
11131  Haraguchi Y, Matsuura K, Kagawa Y, Hasegawa A, Kubo H, Shimizu T.  Rapid creation system of morphologically and functionally communicative three-dimensional cell-dense tissue by centrifugation.  Biotechnol. Prog.  2018  34(6):1447-1453  PubMed ID: 30009512   DOI: 10.1002/btpr.2691
11208  Yamamoto Y, Miyazaki S, Maruyama K, Kobayashi R, Le MNT, Kano A, Kondow A, Fujii S, Ohnuma K.  Random migration of induced pluripotent stem cell-derived human gastrulation-stage mesendoderm.  PLoS ONE  2018    PubMed ID: 30199537   DOI: 10.1371/journal.pone.0201960
11123  Tsuburaya N, Homma K, Higuchi T, Balia A, Yamakoshi H, Shibata N, Nakamura S, Nakagawa H, Ikeda SI, Umezawa N, Kato N, Yokoshima S, Shibuya M, Shimonishi M, Kojima H, Okabe T, Nagano T, Naguro I, Imamura K, Inoue H, Fujisawa T, Ichijo H.  A small-molecule inhibitor of SOD1-Derlin-1 interaction ameliorates pathology in an ALS mouse model.  Nat Commun  2018  9(1):2668  PubMed ID: 29991716   DOI: 10.1038/s41467-018-05127-2
11234  Yasuda S, Kusakawa S, Kuroda T, Miura T, Tano K, Takada N, Matsuyama S, Matsuyama A, Nasu M, Umezawa A, Hayakawa T, Tsutsumi H, Sato Y.  Tumorigenicity-associated characteristics of human iPS cell lines.  PLoS ONE  2018    PubMed ID: 30286143   DOI: 10.1371/journal.pone.0205022
4048  Shibata S, Hayashi R, Okubo T, Kudo Y, Katayama T, Ishikawa Y, Toga J, Yagi E, Honma Y, Quantock AJ, Sekiguchi K, Nishida K.  Selective Laminin-Directed Differentiation of Human Induced Pluripotent Stem Cells into Distinct Ocular Lineages  Cell Rep  2018  25(6):1668-1679  PubMed ID: 30404017   DOI: 10.1016/j.celrep.2018.10.032
11240  Tajiri S, Yamanaka S, Fujimoto T, Matsumoto K, Taguchi A, Nishinakamura R, Okano HJ, Yokoo T.  Regenerative potential of induced pluripotent stem cells derived from patients undergoing haemodialysis in kidney regeneration.  Sci Rep  2018    PubMed ID: 30297790   DOI: 10.1038/s41598-018-33256-7
11251  Murata H, Khine CC, Nishikawa A, Yamamoto KI, Kinoshita R, Sakaguchi M.  c-Jun N-terminal kinase (JNK)-mediated phosphorylation of SARM1 regulates NAD+ cleavage activity to inhibit mitochondrial respiration.  J. Biol. Chem.  2018    PubMed ID: 30333228   DOI: 10.1074/jbc.RA118.004578
11290  Hayashi R, Ishikawa Y, Katayama T, Quantock AJ, Nishida K.  CD200 facilitates the isolation of corneal epithelial cells derived from human pluripotent stem cells.  Sci Rep  2018    PubMed ID: 30410112   DOI: 10.1038/s41598-018-34845-2
4068  Takako Tsugata, Naruo Nikoh, Tatsuya Kin, Chika Miyagi-Shiohira, Yoshiki Nakashima, Issei Saitoh, Yasufumi Noguchi, Hideo Ueki, Masami Watanabe6 Naoya Kobayashi, Andrew M. James Shapiro2 Hirofumi Noguchi  Role of Egr1 on Pancreatic Endoderm Differentiation  Cell Medicine  2018  10  PubMed ID: 32634182   DOI: 10.1177/2155179017733177
4111  Ide K, Mitsui K, Irie R, Matsushita Y, Ijichi N, Toyodome S, Kosai KI.  A Novel Construction of Lentiviral Vectors for Eliminating Tumorigenic Cells from Pluripotent Stem Cells.  Stem Cells  2018    PubMed ID: 29067732   DOI: 10.1002/stem.2725
4112  Tachikawa S, Shimizu M, Maruyama K, Ohnuma K.  Thalidomide induces apoptosis during early mesodermal differentiation of human induced pluripotent stem cells.  In Vitro Cell. Dev. Biol. Anim.  2018    PubMed ID: 29435726   DOI: 10.1007/s11626-018-0234-x
4113  Shoji M, Minato H, Ogaki S, Seki M, Suzuki Y, Kume S, Kuzuhara T.  Different murine-derived feeder cells alter the definitive endoderm differentiation of human induced pluripotent stem cells.  PLoS ONE  2018    PubMed ID: 30048506   DOI: 10.1371/journal.pone.0201239
4114  Eto S, Goto M, Soga M, Kaneko Y, Uehara Y, Mizuta H, Era T.  Mesenchymal stem cells derived from human iPS cells via mesoderm and neuroepithelium have different features and therapeutic potentials.  PLoS ONE  2018    PubMed ID: 30044827   DOI: 10.1371/journal.pone.0200790
4115  Tomizawa M, Shinozaki F, Motoyoshi Y, Sugiyama T, Yamamoto S, Ishige N.  Oct3/4 is potentially useful for the suppression of the proliferation and motility of hepatocellular carcinoma cells.  Oncol Lett  2018    PubMed ID: 30250594   DOI: 10.3892/ol.2018.9292
4456  Matsuura K, Ito K, Shiraki N, Kume S, Hagiwara N, Shimizu T.  Induced Pluripotent Stem Cell Elimination in a Cell Sheet by Methionine-Free and 42°C Condition for Tumor Prevention.  Tissue Eng Part C Methods  2018  24(10):605-615  PubMed ID: 30234460   DOI: 10.1089/ten.TEC.2018.0228
4457  Kikuchi T, Kino-Oka M, Wada M, Kobayashi T, Kato M, Takeda S, Kubo H, Ogawa T, Sunayama H, Tanimoto K, Mizutani M, Shimizu T, Okano T.  A novel, flexible and automated manufacturing facility for cell-based health care products: Tissue Factory.  Regen Ther  2018  9:89-99  PubMed ID: 30525079   DOI: 10.1016/j.reth.2018.08.004
4458  Kobayashi H, Ebisawa K, Kambe M, Kasai T, Suga H, Nakamura K, Narita Y, Ogata A, Kamei Y.  <Editors' Choice> Effects of exosomes derived from the induced pluripotent stem cells on skin wound healing.  Nagoya J Med Sci  2018  80(2):141-153  PubMed ID: 29915432   DOI: 10.18999/nagjms.80.2.141
4459  Sasaki D, Matsuura K, Seta H, Haraguchi Y, Okano T, Shimizu T.  Contractile force measurement of human induced pluripotent stem cell-derived cardiac cell sheet-tissue.  PLoS ONE  2018  13(5):e0198026  PubMed ID: 29791489   DOI: 10.1371/journal.pone.0198026
4460  Hamano S, Tomokiyo A, Hasegawa D, Yoshida S, Sugii H, Mitarai H, Fujino S, Wada N, Maeda H.  Extracellular Matrix from Periodontal Ligament Cells Could Induce the Differentiation of Induced Pluripotent Stem Cells to Periodontal Ligament Stem Cell-Like Cells.  Stem Cells Dev.  2018  27(2):100-111  PubMed ID: 29160151   DOI: 10.1089/scd.2017.0077
4461  Matsuda Y, Takahashi K, Kamioka H, Naruse K.  Human gingival fibroblast feeder cells promote maturation of induced pluripotent stem cells into cardiomyocytes.  Biochem. Biophys. Res. Commun.  2018  503(3):1798-1804  PubMed ID: 30060947   DOI: 10.1016/j.bbrc.2018.07.116
5773  Kim MH, Matsubara Y, Fujinaga Y, Kino-Oka M.  A Simple and Robust Method for Culturing Human-Induced Pluripotent Stem Cells in an Undifferentiated State Using Botulinum Hemagglutinin.  Biotechnol J  2018  13(2)  PubMed ID: 29027750   DOI: 10.1002/biot.201700384
5775  Kobayashi W, Onishi A, Tu HY, Takihara Y, Matsumura M, Tsujimoto K, Inatani M, Nakazawa T, Takahashi M.  Culture Systems of Dissociated Mouse and Human Pluripotent Stem Cell-Derived Retinal Ganglion Cells Purified by Two-Step Immunopanning.  Invest Ophthalmol Vis Sci  2018  59(2):776-787  PubMed ID: 29392326   DOI: 10.1167/iovs.17-22406
5776  Sumaru K, Takagi T, Morishita K, Kanamori T.  Photoresponsive Aqueous Dissolution of Poly( N-Isopropylacrylamide) Functionalized with o-Nitrobenzaldehyde through Phase Transition.  Biomacromolecules  2018  19(7):2913-2922  PubMed ID: 29641886   DOI: 10.1021/acs.biomac.8b00470
5777  Nakashima Y, Miyagi-Shiohira C, Noguchi H2, Omasa T.  Atorvastatin Inhibits the HIF1α-PPAR Axis, Which Is Essential for Maintaining the Function of Human Induced Pluripotent Stem Cells.  Mol Ther  2018  26(7):1715-1734  PubMed ID: 29929789   DOI: 10.1016/j.ymthe.2018.06.005
14923  Nakayama C, Fujita Y, Matsumura W, Ujiie I, Takashima S, Shinkuma S, Nomura T, Abe R, Shimizu H.  The development of induced pluripotent stem cell-derived mesenchymal stem/stromal cells from normal human and RDEB epidermal keratinocytes  J Dermatol Sci  2018  91(3):301-310  PubMed ID: 29933899   DOI: 10.1016/j.jdermsci.2018.06.004
7014  Taguchi A, Nishinakamura R.  Higher-Order Kidney Organogenesis from Pluripotent Stem Cells.  Cell Stem Cell  2017  21(6):730-746  PubMed ID: 29129523   DOI: 10.1016/j.stem.2017.10.011
7022  Nihongaki Y, Furuhata Y, Otabe T, Hasegawa S, Yoshimoto K, Sato M.  CRISPR-Cas9-based photoactivatable transcription systems to induce neuronal differentiation.  Nat. Methods  2017  14:963-966  PubMed ID: 28892089   DOI: 10.1038/nmeth.4430
7037  Goparaju SK, Kohda K, Ibata K, Soma A, Nakatake Y, Akiyama T, Wakabayashi S, Matsushita M, Sakota M, Kimura H, Yuzaki M, Ko SB, Ko MS.  Rapid differentiation of human pluripotent stem cells into functional neurons by mRNAs encoding transcription factors.  Sci Rep  2017  7:42367  PubMed ID: 28205555   DOI: 10.1038/srep42367
9814  Suga M, Tachikawa S, Tateyama D, Ohnuma K, Furue MK.  Imaging-cytometry revealed spatial heterogeneities of marker expression in undifferentiated human pluripotent stem cells.  In Vitro Cell. Dev. Biol. Anim.  2017  53:83-91  PubMed ID: 27573412   DOI: 10.1007/s11626-016-0084-3
9842  Ozeki N, Hase N, Higuchi N, Hiyama T, Yamaguchi H, Kawai R, Matsumoto T, Nakata K, Mogi M.  Gelatin scaffold combined with bone morphogenetic protein-4 induces odontoblast-like cell differentiation involving integrin profile changes, autophagy-related gene 10, and Wnt5 sequentially in human induced pluripotent stem cells.  Differentiation  2017  93:1-14  PubMed ID: 27639333   DOI: 10.1016/j.diff.2016.09.002
10099  Ozeki N, Hase N, Hiyama T, Yamaguchi H, Kawai-Asano R, Nakata K, Mogi M.  MicroRNA-211 and autophagy-related gene 14 signaling regulate osteoblast-like cell differentiation of human induced pluripotent stem cells.  Exp. Cell Res.  2017  352:63-74  PubMed ID: 28159471   DOI: 10.1016/j.yexcr.2017.01.018
10124  Nagasaka R, Gotou Y, Yoshida K, Kanie K, Shimizu K, Honda H, Kato R.  Image-based cell quality evaluation to detect irregularities under same culture process of human induced pluripotent stem cells.  J. Biosci. Bioeng.  2017  123:642-650  PubMed ID: 28189491   DOI: 10.1016/j.jbiosc.2016.12.015
10162  Haraguchi Y, Hasegawa A, Matsuura K, Kobayashi M, Iwana SI, Kabetani Y, Shimizu T.  Three-Dimensional Human Cardiac Tissue Engineered by Centrifugation of Stacked Cell Sheets and Cross-Sectional Observation of Its Synchronous Beatings by Optical Coherence Tomography.  Biomed Res Int  2017  2017:5341702  PubMed ID: 28326324   DOI: 10.1155/2017/5341702
10212  Takahashi M, Saito A, Jimbo Y, Nakasono S.  Evaluation of the effects of power-frequency magnetic fields on the electrical activity of cardiomyocytes differentiated from human induced pluripotent stem cells.  J Toxicol Sci  2017  42:223-231  PubMed ID: 28321048   DOI: 10.2131/jts.42.223
10276  Kondo Y, Hattori K, Tashiro S, Nakatani E, Yoshimitsu R, Satoh T, Sugiura S, Kanamori T, Ohnuma K.  Compartmentalized microfluidic perfusion system to culture human induced pluripotent stem cell aggregates.  J. Biosci. Bioeng.  2017  124:234-241  PubMed ID: 28434976   DOI: 10.1016/j.jbiosc.2017.03.014
10279  Tomizawa M, Shinozaki F, Motoyoshi Y, Sugiyama T, Yamamoto S, Ishige N.  Differentiation of human induced pluripotent stem cells in William's E initiation medium supplemented with 3‑bromopyruvate and 2‑deoxy‑d‑glucose.  Mol Med Rep  2017  15:3719-3723  PubMed ID: 28440498   DOI: 10.3892/mmr.2017.6474
10346  Ishikawa T.  Next-generation sequencing traces human induced pluripotent stem cell lines clonally generated from heterogeneous cancer tissue.  World J Stem Cells  2017  9:77-88  PubMed ID: 28596815   DOI: 10.4252/wjsc.v9.i5.77
10409  Bamba Y, Kanemura Y, Okano H, Yamasaki M.  Visualization of migration of human cortical neurons generated from induced pluripotent stem cells.  J. Neurosci. Methods  2017  289:57-63  PubMed ID: 28694214   DOI: 10.1016/j.jneumeth.2017.07.004
10426  Tateno H, Saito S.  Engineering of a Potent Recombinant Lectin-Toxin Fusion Protein to Eliminate Human Pluripotent Stem Cells.  Molecules  2017  22:  PubMed ID: 28698527   DOI: 10.3390/molecules22071151
10447  Taniguchi J, Pandian GN, Hidaka T, Hashiya K, Bando T, Kim KK, Sugiyama H.  A synthetic DNA-binding inhibitor of SOX2 guides human induced pluripotent stem cells to differentiate into mesoderm.  Nucleic Acids Res.  2017  45:9219-9228  PubMed ID: 28934500   DOI: 10.1093/nar/gkx693
10484  Tachikawa S, Nishimura T, Nakauchi H, Ohnuma K.  Thalidomide induces apoptosis in undifferentiated human induced pluripotent stem cells.  In Vitro Cell. Dev. Biol. Anim.  2017  53:841-851  PubMed ID: 28849348   DOI: 10.1007/s11626-017-0192-8
10529  Hosoyama T, Ichida S, Kanno M, Ishihara R, Hatashima T, Ueno K, Hamano K.  Microgravity influences maintenance of the human muscle stem/progenitor cell pool.  Biochem. Biophys. Res. Commun.  2017  493:998-1003  PubMed ID: 28942144   DOI: 10.1016/j.bbrc.2017.09.103
10593  Hasegawa D, Ochiai-Shino H, Onodera S, Nakamura T, Saito A, Onda T, Watanabe K, Nishimura K, Ohtaka M, Nakanishi M, Kosaki K, Yamaguchi A, Shibahara T, Azuma T.  Gorlin syndrome-derived induced pluripotent stem cells are hypersensitive to hedgehog-mediated osteogenic induction.  PLoS ONE  2017  12:e0186879  PubMed ID: 29088246   DOI: 10.1371/journal.pone.0186879
10667  Bamba Y, Nonaka M, Sasaki N, Shofuda T, Kanematsu D, Suemizu H, Higuchi Y, Pooh RK, Kanemura Y, Okano H, Yamasaki M.  Generation of Induced Pluripotent Stem Cells and Neural Stem/Progenitor Cells from Newborns with Spina Bifida Aperta.  Asian Spine J  2017  11:870-879  PubMed ID: 29279741   DOI: 10.4184/asj.2017.11.6.870
10690  Kavitha MS, Kurita T, Park SY, Chien SI, Bae JS, Ahn BC.  Deep vector-based convolutional neural network approach for automatic recognition of colonies of induced pluripotent stem cells.  PLoS ONE  2017  12:e0189974  PubMed ID: 29281701   DOI: 10.1371/journal.pone.0189974
4551  Hayashi R, Ishikawa Y, Katori R, Sasamoto Y, Taniwaki Y, Takayanagi H, Tsujikawa M, Sekiguchi K, Quantock AJ, Nishida K.  Coordinated generation of multiple ocular-like cell lineages and fabrication of functional corneal epithelial cell sheets from human iPS cells.  Nat Protoc  2017  12(4):683-696  PubMed ID: 28253236   DOI: 10.1038/nprot.2017.007
5760  Tomizawa M, Shinozaki F, Motoyoshi Y, Sugiyama T, Yamamoto S, Ishige N.  2‑Deoxy‑D‑glucose initiates hepatocyte differentiation in human induced pluripotent stem cells.  Mol Med Rep  2017  15(5):3083-3087  PubMed ID: 28358426   DOI: 10.3892/mmr.2017.6405
5761  Tomizawa M, Shinozaki F, Motoyoshi Y, Sugiyama T, Yamamoto S, Ishige N.  Oncostatin M in William's E medium is suitable for initiation of hepatocyte differentiation in human induced pluripotent stem cells.  Mol Med Rep  2017  15(5):3088-3092  PubMed ID: 28358419   DOI: 10.3892/mmr.2017.6406
5762  Hasehira K, Hirabayashi J, Tateno H.  Structural and quantitative evidence of α2-6-sialylated N-glycans as markers of the differentiation potential of human mesenchymal stem cells.  Glycoconj J  2017  34(6):797-806  PubMed ID: 27314244   DOI: 10.1007/s10719-016-9699-6
5763  K Sumaru et al  Sectioning of cultured cell monolayer using photo-acid-generating substrate and micro-patterned light projection  European Polymer Journal   2017  93:733-742    DOI: 10.1016/j.eurpolymj.2017.02.021
5764  Tani H, Okuda S, Nakamura K, Aoki M, Umemura T.  Short-lived long non-coding RNAs as surrogate indicators for chemical exposure and LINC00152 and MALAT1 modulate their neighboring genes.  PLoS One  2017  12(7):e0181628  PubMed ID: 28719640   DOI: 10.1371/journal.pone.0181628
5765  Tateno H et al  Development of a practical sandwich assay to detect human pluripotent stem cells using cell culture media.  Regen Ther  2017  6:1-8  PubMed ID: 30271833   DOI: 10.1016/j.reth.2016.12.002
5766  Suzuki N, Arimitsu N, Shimizu J, Takai K, Hirotsu C, Ueda Y, Wakisaka S, Fujiwara N, Suzuki T.  Neuronal Cell Sheets of Cortical Motor Neuron Phenotype Derived from Human iPSCs.  Cell Transplant  2017  26(8):1355-1364  PubMed ID: 28901192   DOI: 10.1177/0963689717720280
5767  Ito M, Sun S, Fukuhara T, Suzuki R, Tamai M, Yamauchi T, Nakashima K, Tagawa Y, Okazaki S, Matsuura Y, Wakita T, Suzuki T.  Development of hepatoma-derived, bidirectional oval-like cells as a model to study host interactions with hepatitis C virus during differentiation.  Oncotarget  2017  8(33):53899-53915  PubMed ID: 28903311   DOI: 10.18632/oncotarget.19108
5768  Alsayegh K, Matsuura K, Sekine H, Shimizu T.  Dinaciclib potently suppresses MCL-1 and selectively induces the cell death in human iPS cells without affecting the viability of cardiac tissue.  Sci Rep  2017  7:45577  PubMed ID: 28361959   DOI: 10.1038/srep45577
5769  Kuroda T, Yasuda S, Nakashima H, Takada N, Matsuyama S, Kusakawa S, Umezawa A, Matsuyama A, Kawamata S, Sato Y  dentification of a Gene Encoding Slow Skeletal Muscle Troponin T as a Novel Marker for Immortalization of Retinal Pigment Epithelial Cells.  Sci Rep  2017  7(1):8163  PubMed ID: 28811571   DOI: 10.1038/s41598-017-08014-w
5770  Seta H, Matsuura K, Sekine H, Yamazaki K, Shimizu T.  Tubular Cardiac Tissues Derived from Human Induced Pluripotent Stem Cells Generate Pulse Pressure In Vivo.  Sci Rep  2017  7:45499  PubMed ID: 28358136   DOI: 10.1038/srep45499
5771  Hayakawa K, Sakamoto Y, Kanie O, Ohtake A, Daikoku S, Ito Y, Shiota K.  Reactivation of hyperglycemia-induced hypocretin (HCRT) gene silencing by N-acetyl-d-mannosamine in the orexin neurons derived from human iPS cells.  Epigenetics  2017  12(9):764-778  PubMed ID: 28762874   DOI: 10.1080/15592294.2017.1346775
5772  Sato M etal  Regeneration of cervical reserve cell-like cells from human induced pluripotent stem cells (iPSCs): A new approach to finding targets for cervical cancer stem cell treatment.  Oncotarget  2017  8(25):40935-40945  PubMed ID: 28402962   DOI: 10.18632/oncotarget.16783
5774  Miyagoe-Suzuki Y, Nishiyama T, Nakamura M, Narita A, Takemura F, Masuda S, Minami N, Murayama K, Komaki H, Goto YI, Takeda S.  Induction of Pluripotent Stem Cells from a Manifesting Carrier of Duchenne Muscular Dystrophy and Characterization of Their X-Inactivation Status.  Stem Cells Int  2017  2017:7906843  PubMed ID: 28491099   DOI: 10.1155/2017/7906843
7048  Suzuki K, Kimura T, Shinoda H, Bai G, Daniels MJ, Arai Y, Nakano M, Nagai T.  Five colour variants of bright luminescent protein for real-time multicolour bioimaging.  Nat Commun  2016  7:13718  PubMed ID: 27966527   DOI: 10.1038/ncomms13718
7080  Hayashi R, Ishikawa Y, Sasamoto Y, Katori R, Nomura N, Ichikawa T, Araki S, Soma T, Kawasaki S, Sekiguchi K, Quantock AJ, Tsujikawa M, Nishida K.  Co-ordinated ocular development from human iPS cells and recovery of corneal function.  Nature  2016  531:376-80  PubMed ID: 26958835   DOI: 10.1038/nature17000
7083  Matsuura K, Seta H, Haraguchi Y, Alsayegh K, Sekine H, Shimizu T, Hagiwara N, Yamazaki K, Okano T.  TRPV-1-mediated elimination of residual iPS cells in bioengineered cardiac cell sheet tissues.  Sci Rep  2016  6:21747  PubMed ID: 26888607   DOI: 10.1038/srep21747
7315  Imaizumi K, Iha M, Nishishita N, Kawamata S, Nishikawa S, Akuta T.  A Simple and Efficient Method of Slow Freezing for Human Embryonic Stem Cells and Induced Pluripotent Stem Cells.  Methods Mol. Biol.  2016  1341:15-24  PubMed ID: 26069023   DOI: 10.1007/7651_2015_211
7326  Kim SI, Oceguera-Yanez F, Sakurai C, Nakagawa M, Yamanaka S, Woltjen K.  Inducible Transgene Expression in Human iPS Cells Using Versatile All-in-One piggyBac Transposons.  Methods Mol. Biol.  2016  1357:111-31  PubMed ID: 26025620   DOI: 10.1007/7651_2015_251
9529  Tomizawa M, Shinozaki F, Motoyoshi Y, Sugiyama T, Yamamoto S, Ishige N.  Transcription Factors and Medium Suitable for Initiating the Differentiation of Human-Induced Pluripotent Stem Cells to the Hepatocyte Lineage.  J. Cell. Biochem.  2016  117:2001-9  PubMed ID: 26773721   DOI: 10.1002/jcb.25494
9535  Shoji M, Nishioka M, Minato H, Harada K, Kubo M, Fukuyama Y, Kuzuhara T.  Neurotrophic activity of jiadifenolide on neuronal precursor cells derived from human induced pluripotent stem cells.  Biochem. Biophys. Res. Commun.  2016  470:798-803  PubMed ID: 26809091   DOI: 10.1016/j.bbrc.2016.01.092
9660  Tomizawa M, Shinozaki F, Motoyoshi Y, Sugiyama T, Yamamoto S, Ishige N.  Improved Survival and Initiation of Differentiation of Human Induced Pluripotent Stem Cells to Hepatocyte-Like Cells upon Culture in William's E Medium followed by Hepatocyte Differentiation Inducer Treatment.  PLoS ONE  2016  11:e0153435  PubMed ID: 27073925   DOI: 10.1371/journal.pone.0153435
9698  Horiguchi I, Sakai Y.  Serum replacement with albumin-associated lipids prevents excess aggregation and enhances growth of induced pluripotent stem cells in suspension culture.  Biotechnol. Prog.  2016  32:1009-16  PubMed ID: 27193385   DOI: 10.1002/btpr.2301
9756  Bamba Y, Shofuda T, Kato M, Pooh RK, Tateishi Y, Takanashi J, Utsunomiya H, Sumida M, Kanematsu D, Suemizu H, Higuchi Y, Akamatsu W, Gallagher D, Miller FD, Yamasaki M, Kanemura Y, Okano H.  In vitro characterization of neurite extension using induced pluripotent stem cells derived from lissencephaly patients with TUBA1A missense mutations.  Mol Brain  2016  9:70  PubMed ID: 27431206   DOI: 10.1186/s13041-016-0246-y
9794  Shimba K, Iida S, Kotani K, Jimbo Y.  Cell-cycle-dependent Ca2+ transients in human induced pluripotent stem cells revealed by a simultaneous imaging of cell nuclei and intracellular Ca2+ level.  Integr Biol (Camb)  2016  8:985-990  PubMed ID: 27713967   DOI: 10.1039/c6ib00074f
9800  Seno A, Kasai T, Ikeda M, Vaidyanath A, Masuda J, Mizutani A, Murakami H, Ishikawa T, Seno M.  Characterization of Gene Expression Patterns among Artificially Developed Cancer Stem Cells Using Spherical Self-Organizing Map.  Cancer Inform  2016  15:163-78  PubMed ID: 27559294   DOI: 10.4137/CIN.S39839
9838  Tomotsune D, Hirashima K, Fujii M, Yue F, Matsumoto K, Takizawa-Shirasawa S, Yokoyama T, Sasaki K.  Enrichment of Pluripotent Stem Cell-Derived Hepatocyte-Like Cells by Ammonia Treatment.  PLoS ONE  2016  11:e0162693  PubMed ID: 27632182   DOI: 10.1371/journal.pone.0162693
9853  Imamura T, Fujita K, Tagawa K, Ikura T, Chen X, Homma H, Tamura T, Mao Y, Taniguchi JB, Motoki K, Nakabayashi M, Ito N, Yamada K, Tomii K, Okano H, Kaye J, Finkbeiner S, Okazawa H.  Identification of hepta-histidine as a candidate drug for Huntington's disease by in silico-in vitro- in vivo-integrated screens of chemical libraries.  Sci Rep  2016  6:33861  PubMed ID: 27653664   DOI: 10.1038/srep33861
10851  Hayashi K, Ochiai-Shino H, Shiga T, Onodera S, Saito A, Shibahara T, Azuma T.  Transplantation of human-induced pluripotent stem cells carried by self-assembling peptide nanofiber hydrogel improves bone regeneration in rat calvarial bone defects  BDJ Open  2016  2:15007  PubMed ID: 29607061   DOI: 10.1038/bdjopen.2015.7
10891    Human iPS cell derived neural cell sheets exhibit mature neural and extendable scaffold functions and promote recovery in injured mouse spinal cords  J Stem Cell Res Med  2016  1: 41-47    DOI: 10.15761/JSCRM.1000107
5758  Ashida T, Sakai S1, Taya M1.  Propagation of human iPS cells in alginate-based microcapsules prepared using reactions catalyzed by horseradish peroxidase and catalase.  Artif Cells Nanomed Biotechnol.   2016  44(6):1406-9  PubMed ID: 26148179   DOI: 10.3109/21691401.2015.1029631
5759  Takayama Y, Kida YS.  In Vitro Reconstruction of Neuronal Networks Derived from Human iPS Cells Using Microfabricated Devices.  PLoS One  2016  11(2):e0148559  PubMed ID: 26848955   DOI: 10.1371/journal.pone.0148559
13997  Matsumoto R, Shimizu K, Nagashima T, Tanaka H, Mizuno M, Kikkawa F, Hori M, Honda H.  Plasma-activated medium selectively eliminates undifferentiated human induced pluripotent stem cells  Regen Ther  2016  5:55-63  PubMed ID: 31245502   DOI: 10.1016/j.reth.2016.07.001
14189  Ryuhei Hayashi, Ryuhei Hayashi, Yuki Ishikawa, Ryosuke Katori, Yuki Taniwaki, Motokazu Tsujikawa, Andrew J. Quantock, Kohji Nishida  Fabrication of a Corneal Epithelial Cell Sheet from Human Pluripotent Stem Cells by a Method Based on Spontaneous Ocular Cell Differentiation  Protocol Exchange  2016      DOI: 10.1038/protex.2016.009
7204  Tomizawa M, Shinozaki F, Motoyoshi Y, Sugiyama T, Yamamoto S, Ishige N.  Involvement of the Wnt signaling pathway in feeder-free culture of human induced pluripotent stem cells.  Mol Med Rep  2015  12:6797-800  PubMed ID: 26398905   DOI: 10.3892/mmr.2015.4314
7223  Arai Y, Hayakawa K, Arai D, Ito R, Iwasaki Y, Saito K, Akutsu K, Takatori S, Ishii R, Hayashi R, Izumi S, Sugino N, Kondo F, Horie M, Nakazawa H, Makino T, Hirosawa M, Shiota K, Ohgane J.  Putative Epimutagens in Maternal Peripheral and Cord Blood Samples Identified Using Human Induced Pluripotent Stem Cells.  Biomed Res Int  2015  2015:876047  PubMed ID: 26339649   DOI: 10.1155/2015/876047
7271  Fujiwara N, Shimizu J, Takai K, Arimitsu N, Ueda Y, Wakisaka S, Suzuki T, Suzuki N.  Cellular and molecular mechanisms of the restoration of human APP transgenic mouse cognitive dysfunction after transplant of human iPS cell-derived neural cells.  Exp. Neurol.  2015  271:423-31  PubMed ID: 26196079   DOI: 10.1016/j.expneurol.2015.07.008
7364  Arai Y, Yamamoto T, Minamikawa T, Takamatsu T, Nagai T.  Spectral fingerprinting of individual cells visualized by cavity-reflection-enhanced light-absorption microscopy.  PLoS ONE  2015  10:e0125733  PubMed ID: 25950513   DOI: 10.1371/journal.pone.0125733
7482  Tomizawa M, Shinozaki F, Motoyoshi Y, Sugiyama T, Yamamoto S, Ishige N.  An Optimal Medium Supplementation Regimen for Initiation of Hepatocyte Differentiation in Human Induced Pluripotent Stem Cells.  J. Cell. Biochem.  2015  116:1479-89  PubMed ID: 25683148   DOI: 10.1002/jcb.25139
7495  Kato H, Ochiai-Shino H, Onodera S, Saito A, Shibahara T, Azuma T.  Promoting effect of 1,25(OH)2 vitamin D3 in osteogenic differentiation from induced pluripotent stem cells to osteocyte-like cells.  Open Biol  2015  5:140201  PubMed ID: 25652541   DOI: 10.1098/rsob.140201
7521  Binata Joddar, Chieko Nishioka, Eiki Takahashi, Yoshihiro Ito  Chemically fixed autologous feeder cell-derived niche for human induced pluripotent stem cell culture.  J Mater Chem B.  2015  3:2301-2307  PubMed ID: 32262060   DOI: 10.1039/C4TB01635A
7542  M Iinuma, T Umehara, N Arimitsu, J Shimizu, H Misawa, K Takai, N Fujiwara, A Fujii, Y Ueda, S Wakisaka, T Suzuki, C Hirotsu, M Beppu, N Suzuki  Induction of neural cells with spinal motoneuron phenotype from human iPS cells and the trans-plantation to totally transected spinal cords in mice.  Inflammation and Regeneration  2015  35:154-163    DOI: 10.2492/inflammregen.35.154
7550  N Kuzumaki, M Narita  δ-Opioids and Neurogenesis.  Y. Xia (ed.), Neural Functions of the Delta-Opioid Receptor  2015  9:389-398    DOI: 10.1007/978-3-319-25495-1_9
7562  Takuya Kuroda, Satoshi Yasuda, Satoko Matsuyama a, Keiko Tano, Shinji Kusakawa, Yoshiki Sawa, Shin Kawamata, Yoji Sato  Highly sensitive droplet digital PCR method for detection of residual undifferentiated cells in cardiomyocytes derived from human pluripotent stem cells.  Regenerative Therapy  2015  2:17-23  PubMed ID: 31245455   DOI: 10.1016/j.reth.2015.08.001
5449  Tateno H, Onuma Y, Ito Y, Minoshima F, Saito S, Shimizu M, Aiki Y, Asashima M, Hirabayashi J.  Elimination of tumorigenic human pluripotent stem cells by a recombinant lectin-toxin fusion protein.  Stem Cell Reports  2015  4(5):811-20  PubMed ID: 25866158   DOI: 10.1016/j.stemcr.2015.02.016
5697  Ishikawa T, Kobayashi M, Yanagi S, Kato C, Takashima R, Kobayashi E, Hagiwara K, Ochiya T  Human induced hepatic lineage-oriented stem cells: autonomous specification of human iPS cells toward hepatocyte-like cells without any exogenous differentiation factors.  PLoS One  2015  10(4):e0123193  PubMed ID: 25875613   DOI: 10.1371/journal.pone.0123193
5729  Matsuura K, Kodama F, Sugiyama K, Shimizu T, Hagiwara N, Okano T.  Elimination of remaining undifferentiated induced pluripotent stem cells in the process of human cardiac cell sheet fabrication using a methionine-free culture condition.  Tissue Eng Part C Methods  2015  21(3):330-8  PubMed ID: 25245976   DOI: 10.1089/ten.TEC.2014.0198
5747  Kawamata S, Kanemura H, Sakai N, Takahashi M, Go MJ.  Design of a Tumorigenicity Test for Induced Pluripotent Stem Cell (iPSC)-Derived Cell Products.  J Clin Med  2015  4(1):159-71  PubMed ID: 26237025   DOI: 10.3390/jcm4010159
5749  Takenaka C, Miyajima H, Yoda Y, Imazato H, Yamamoto T, Gomi S, Ohshima Y, Kagawa K, Sasaki T, Kawamata S.  Controlled Growth and the Maintenance of Human Pluripotent Stem Cells by Cultivation with Defined Medium on Extracellular Matrix-Coated Micropatterned Dishes.  PLoS One  2015  10(6):e0129855  PubMed ID: 26115194   DOI: 10.1371/journal.pone.0129855
5751  Morita A, Soga K, Nakayama H, Ishida T, Kawanishi S, Sato EF.  Neuronal differentiation of human iPS cells induced by baicalin via regulation of bHLH gene expression.  Biochem Biophys Res Commun  2015  465(3):458-63  PubMed ID: 26277393   DOI: 10.1016/j.bbrc.2015.08.039
5752  Onuma Y, Higuchi K, Aiki Y, Shu Y, Asada M, Asashima M, Suzuki M, Imamura T, Ito Y.  A stable chimeric fibroblast growth factor (FGF) can successfully replace basic FGF in human pluripotent stem cell culture.  PLoS One  2015  10(4):e0118931  PubMed ID: 25850016   DOI: 10.1371/journal.pone.0118931
5753  Komatsu M, Konagaya S, Egawa EY, Iwata H.  Maturation of human iPS cell-derived dopamine neuron precursors in alginate-Ca(2+) hydrogel.  Biochim Biophys Acta  2015  1850(9):1669-75  PubMed ID: 25952075   DOI: 10.1016/j.bbagen.2015.04.011
5754  Cieślar-Pobuda A, Jain MV, Kratz G, Rzeszowska-Wolny J, Ghavami S, Wiechec E.  The expression pattern of PFKFB3 enzyme distinguishes between induced-pluripotent stem cells and cancer stem cells.  Oncotarget  2015  6(30):29753-70  PubMed ID: 26337471   DOI: 10.18632/oncotarget.4995
5755  Konagaya S, Iwata H.  Microencapsulation of dopamine neurons derived from human induced pluripotent stem cells.  Biochim Biophys Acta  2015  1850(1):22-32  PubMed ID: 25281770   DOI: 10.1016/j.bbagen.2014.09.025
5756  Shimojima K, Okumura A, Hayashi M, Kondo T, Inoue H, Yamamoto T.  CHCHD2 is down-regulated in neuronal cells differentiated from iPS cells derived from patients with lissencephaly.  Genomics  2015  106(4):196-203  PubMed ID: 26188257   DOI: 10.1016/j.ygeno.2015.07.001
5757  Haraguchi Y, Matsuura K, Shimizu T, Yamato M, Okano T.  Simple suspension culture system of human iPS cells maintaining their pluripotency for cardiac cell sheet engineering.  J Tissue Eng Regen Med  2015  9(12):1363-75  PubMed ID: 23728860   DOI: 10.1002/term.1761
5794  Mitsui K, Ide K, Takayama A, Wada T, Irie R, Kosai K.  Conditionally replicating adenovirus prevents pluripotent stem cell-derived teratoma by specifically eliminating undifferentiated cells.  Mol Ther Methods Clin Dev  2015  2:15026  PubMed ID: 26269798   DOI: 10.1038/mtm.2015.26
5708  Daisuke Takahashi, Masato Sasaki, Kuniaki Nagamine, Keiichi Torimitsu, and Matsuhiko Nishizawa  Electroporation of Adherent Cells by Direct Lamination of Hydrogel-based Microelectrode Substrates  Chem. Lett  2014  43:444–446    DOI: 10.1246/cl.131083
5724  Ochiai-Shino H, Kato H, Sawada T, Onodera S, Saito A, Takato T, Shibahara T, Muramatsu T, Azuma T.  A novel strategy for enrichment and isolation of osteoprogenitor cells from induced pluripotent stem cells based on surface marker combination.  PLoS One.  2014  9(6):e99534  PubMed ID: 24911063   DOI: 10.1371/journal.pone.0099534
5725  Imaizumi K, Nishishita N, Muramatsu M, Yamamoto T, Takenaka C, Kawamata S, Kobayashi K, Nishikawa S, Akuta T.  A simple and highly effective method for slow-freezing human pluripotent stem cells using dimethyl sulfoxide, hydroxyethyl starch and ethylene glycol.  PLoS One  2014  9(2):e88696  PubMed ID: 24533137   DOI: 10.1371/journal.pone.0088696
5726  Kobayashi J, Yoshida M, Tarui S, Hirata M, Nagai Y, Kasahara S, Naruse K, Ito H, Sano S, Oh H.  Directed differentiation of patient-specific induced pluripotent stem cells identifies the transcriptional repression and epigenetic modification of NKX2-5, HAND1, and NOTCH1 in hypoplastic left heart syndrome.  PLoS One  2014  9(7):e102796  PubMed ID: 25050861   DOI: 10.1371/journal.pone.0102796
5727  Tomizawa M, Shinozaki F, Motoyoshi Y, Sugiyama T, Yamamoto S, Sueishi M.  Dual gene expression in embryoid bodies derived from human induced pluripotent stem cells using episomal vectors.  Tissue Eng Part A  2014  20(23-24):3154-62  PubMed ID: 24980753   DOI: 10.1089/ten.TEA.2014.0132
5728  Tani H, Onuma Y, Ito Y, Torimura M.  Long non-coding RNAs as surrogate indicators for chemical stress responses in human-induced pluripotent stem cells.  PLoS One  2014  9(8):e106282  PubMed ID: 25171338   DOI: 10.1371/journal.pone.0106282
5730  Bamba Y, Shofuda T, Kanematsu D, Nonaka M, Yamasaki M, Okano H, Kanemura Y.  Differentiation, polarization, and migration of human induced pluripotent stem cell-derived neural progenitor cells co-cultured with a human glial cell line with radial glial-like characteristics.  Biochem Biophys Res Commun  2014  447(4):683-8  PubMed ID: 24755070   DOI: 10.1016/j.bbrc.2014.04.070
5731  Tateno H, Onuma Y, Ito Y.  Live-cell imaging of human pluripotent stem cells by a novel lectin probe rBC2LCN.  Methods Mol Biol  2014  1200:313-8  PubMed ID: 25117245   DOI: 10.1007/978-1-4939-1292-6_26
5732  Tokunaga K, Saitoh N, Goldberg IG, Sakamoto C, Yasuda Y, Yoshida Y, Yamanaka S, Nakao M.  Computational image analysis of colony and nuclear morphology to evaluate human induced pluripotent stem cells.  Sci Rep  2014  4:6996  PubMed ID: 25385348   DOI: 10.1038/srep06996
5733  Ohnuma K, Fujiki A, Yanagihara K, Tachikawa S, Hayashi Y, Ito Y, Onuma Y, Chan T, Michiue T, Furue MK, Asashima M  Enzyme-free passage of human pluripotent stem cells by controlling divalent cations.  Sci Rep  2014  4:4646  PubMed ID: 24721898   DOI: 10.1038/srep04646
5734  Tateno H, Onuma Y, Ito Y, Hiemori K, Aiki Y, Shimizu M, Higuchi K, Fukuda M, Warashina M, Honda S, Asashima M, Hirabayashi J.  A medium hyperglycosylated podocalyxin enables noninvasive and quantitative detection of tumorigenic human pluripotent stem cells.  Sci Rep  2014  4:4069  PubMed ID: 24518842   DOI: 10.1038/srep04069
5735  Yamada R, Hattori K, Tachikawa S, Tagaya M, Sasaki T, Sugiura S, Kanamori T, Ohnuma K.  Control of adhesion of human induced pluripotent stem cells to plasma-patterned polydimethylsiloxane coated with vitronectin and γ-globulin.  J Biosci Bioeng  2014  118(3):315-22  PubMed ID: 24656306   DOI: 10.1016/j.jbiosc.2014.02.009
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5737  Ishizuka T, Goshima H, Ozawa A, Watanabe Y.  Involvement of β-adrenoceptors in the differentiation of human induced pluripotent stem cells into mesodermal progenitor cells.  Eur J Pharmacol  2014  740:28-34  PubMed ID: 25014757   DOI: 10.1016/j.ejphar.2014.06.056
5738  Kanemura H, Go MJ, Shikamura M, Nishishita N, Sakai N, Kamao H, Mandai M, Morinaga C, Takahashi M, Kawamata S.  Tumorigenicity studies of induced pluripotent stem cell (iPSC)-derived retinal pigment epithelium (RPE) for the treatment of age-related macular degeneration.  PLoS One  2014  9(1):e85336  PubMed ID: 24454843   DOI: 10.1371/journal.pone.0085336
5739  Yoshimitsu R, Hattori K, Sugiura S, Kondo Y, Yamada R, Tachikawa S, Satoh T, Kurisaki A, Ohnuma K, Asashima M, Kanamori T.  Microfluidic perfusion culture of human induced pluripotent stem cells under fully defined culture conditions.  Biotechnol Bioeng  2014  111(5):937-47  PubMed ID: 24222619   DOI: 10.1002/bit.25150
5740  Horiguchi A, Yazaki K, Aoyagi M, Ohnuki Y, Kurosawa H.  Effective Rho-associated protein kinase inhibitor treatment to dissociate human iPS cells for suspension culture to form embryoid body-like cell aggregates.  J Biosci Bioeng  2014  118(5):588-92  PubMed ID: 24856590   DOI: 10.1016/j.jbiosc.2014.04.008
5741  Tano K, Yasuda S, Kuroda T, Saito H, Umezawa A, Sato Y.  A novel in vitro method for detecting undifferentiated human pluripotent stem cells as impurities in cell therapy products using a highly efficient culture system.  PLoS One  2014  9(10):e110496  PubMed ID: 25347300   DOI: 10.1371/journal.pone.0110496
5742  Higuchi Y, Kawai K, Yamamoto M, Kuronuma M, Ando Y, Katano I, Nakamura M, Suemizu H.  Novel enhanced green fluorescent protein-expressing NOG mouse for analyzing the microenvironment of xenograft tissues.  Exp Anim  2014  63(1):55-62  PubMed ID: 24521863   DOI: 10.1538/expanim.63.55
5743  Kamada M, Mitsui Y, Kumazaki T, Kawahara Y, Matsuo T, Takahashi T.  Tumorigenic risk of human induced pluripotent stem cell explants cultured on mouse SNL76/7 feeder cells.  Biochem Biophys Res Commun  2014  453(3):668-73  PubMed ID: 25305485   DOI: 10.1016/j.bbrc.2014.10.009
5744  Kuroda T, Yasuda S, Sato Y.  In vitro detection of residual undifferentiated cells in retinal pigment epithelial cells derived from human induced pluripotent stem cells.  Methods Mol Biol  2014  1210:183-92  PubMed ID: 25173169   DOI: 10.1007/978-1-4939-1435-7_14
5745  Luo L, Kawakatsu M, Guo CW, Urata Y, Huang WJ, Ali H, Doi H, Kitajima Y, Tanaka T, Goto S, Ono Y, Xin HB, Hamano K, Li TS.  Effects of antioxidants on the quality and genomic stability of induced pluripotent stem cells.  Sci Rep  2014  4:3779  PubMed ID: 24445363   DOI: 10.1038/srep03779
5746  Taguchi A, Kaku Y, Ohmori T, Sharmin S, Ogawa M, Sasaki H, Nishinakamura R.  Redefining the in vivo origin of metanephric nephron progenitors enables generation of complex kidney structures from pluripotent stem cells.  Cell Stem Cell  2014  14(1):53-67  PubMed ID: 24332837   DOI: 10.1016/j.stem.2013.11.010
5748  Tsugata T1, Nikoh N, Kin T, Saitoh I, Noguchi Y, Ueki H, Watanabe M, James Shapiro AM, Noguchi H.  Potential Factors for the Differentiation of ESCs/iPSCs Into Insulin-Producing Cells.  Cell Med  2014  7(2):83-93  PubMed ID: 26858897   DOI: 10.3727/215517914X685178
13757  Ishihara Y, Tsuno S, Kuwamoto S, Yamashita T, Endo Y, Hasegawa J, Miura N.  Hsa-miR-520d converts fibroblasts into CD105+ populations  Drugs R D  2014  14(4):253-64.  PubMed ID: 25303886   DOI: 10.1007/s40268-014-0064-6
15918  Lee JK, Jin HK, Park MH, Kim BR, Lee PH, Nakauchi H, Carter JE, He X, Schuchman EH, Bae JS.  Acid sphingomyelinase modulates the autophagic process by controlling lysosomal biogenesis in Alzheimer's disease  J Exp Med  2014  211(8):1551-70  PubMed ID: 25049335   DOI: 10.1084/jem.20132451
16004  Ryotaro Yamada, Koji Hattori, Motohiro Tagaya, Toru Sasaki, Daisuke Miyamoto, Kohji Nakazawa, Shinji Sugiura, Toshiyuki Kanamori, Kiyoshi Ohnuma  Plasma-Patterned Polydimethylsiloxane Surface With Single-Step Coating with a Mixture of Vitronectin and Albumin Enables the Formation of Small Discs and Spheroids of Human Induced Pluripotent Stem Cells  Plasma Medicine  2014  4:165-176    DOI: 10.1615/plasmamed.2014012077
5707  Tomizawa M, Shinozaki F, Sugiyama T, Yamamoto S, Sueishi M, Yoshida T.  Activin A is essential for Feeder-free culture of human induced pluripotent stem cells.  J Cell Biochem  2013  114(3):584-8  PubMed ID: 22991093   DOI: 10.1002/jcb.24395
5709  Tomizawa M, Shinozaki F, Sugiyama T, Yamamoto S, Sueishi M, Yoshida T.  Survival of primary human hepatocytes and death of induced pluripotent stem cells in media lacking glucose and arginine.  PLoS One  2013  8(8):e71897  PubMed ID: 23967260   DOI: 10.1371/journal.pone.0071897
5710  Fujiwara N, Shimizu J, Takai K, Arimitsu N, Saito A, Kono T, Umehara T, Ueda Y, Wakisaka S, Suzuki T, Suzuki N.  Restoration of spatial memory dysfunction of human APP transgenic mice by transplantation of neuronal precursors derived from human iPS cells.  Neurosci Lett  2013  557 Pt B:129-34  PubMed ID: 24466594  
5711  Saito A, Ochiai H, Okada S, Miyata N, Azuma T.  Suppression of Lefty expression in induced pluripotent cancer cells.  FASEB J  2013  27(6):2165-74  PubMed ID: 23407711   DOI: 10.1096/fj.12-221432
5712  Fukusumi H, Shofuda T, Kanematsu D, Yamamoto A, Suemizu H, Nakamura M, Yamasaki M, Ohgushi M, Sasai Y, Kanemura Y.  Feeder-free generation and long-term culture of human induced pluripotent stem cells using pericellular matrix of decidua derived mesenchymal cells.  PLoS One  2013  8(1):e55226  PubMed ID: 23383118   DOI: 10.1371/journal.pone.0055226
5713  Shofuda T, Fukusumi H, Kanematsu D, Yamamoto A, Yamasaki M, Arita N, Kanemura Y.  A method for efficiently generating neurospheres from human-induced pluripotent stem cells using microsphere arrays.  Neuroreport  2013  24(2):84-90  PubMed ID: 23238165   DOI: 10.1097/WNR.0b013e32835cb677
5714  Onuma Y, Tateno H, Hirabayashi J, Ito Y, Asashima M.  rBC2LCN, a new probe for live cell imaging of human pluripotent stem cells.  Biochem Biophys Res Commun  2013  431(3):524-9  PubMed ID: 23321312   DOI: 10.1016/j.bbrc.2013.01.025
5716  Donai K, Kuroda K, Guo Y, So KH, Sone H, Kobayashi M, Nishimori K, Fukuda T.  Establishment of a reporter system to monitor silencing status in induced pluripotent stem cell lines.  Anal Biochem  2013  443(1):104-12  PubMed ID: 23973628   DOI: 10.1016/j.ab.2013.08.014
5717  Higurashi N, Uchida T, Lossin C, Misumi Y, Okada Y, Akamatsu W, Imaizumi Y, Zhang B, Nabeshima K, Mori MX, Katsurabayashi S, Shirasaka Y, Okano H, Hirose S.  A human Dravet syndrome model from patient induced pluripotent stem cells.  Mol Brain  2013  6:19  PubMed ID: 23639079   DOI: 10.1186/1756-6606-6-19
5718  Tateno H, Matsushima A, Hiemori K, Onuma Y, Ito Y, Hasehira K, Nishimura K, Ohtaka M, Takayasu S, Nakanishi M, Ikehara Y, Nakanishi M, Ohnuma K, Chan T, Toyoda M, Akutsu H, Umezawa A, Asashima M, Hirabayashi J.  Podocalyxin is a glycoprotein ligand of the human pluripotent stem cell-specific probe rBC2LCN.  Stem Cells Transl Med  2013  2(4):265-73  PubMed ID: 23526252   DOI: 10.5966/sctm.2012-0154
5719  Toshiaki Ishizuka Hazuki Goshima Ayako Ozawa Yasuhiro Watanabe  Stimulation ofα1-adrenoceptor or angiotensin type 1 receptorenhances DNA synthesis in human-induced pluripotent stemcells via Gq-coupled receptor-dependent signaling pathways  European Journal of Pharmacology  2013  714:202-209  PubMed ID: 23792040   DOI: 10.1016/j.ejphar.2013.06.003
5720  Tomizawa M, Shinozaki F, Sugiyama T, Yamamoto S, Sueishi M, Yoshida T.  Single-step protocol for the differentiation of human-induced pluripotent stem cells into hepatic progenitor-like cells.  Biomed Rep  2013  1(1):18-22.  PubMed ID: 24648886   DOI: 10.3892/br.2012.2
5722  Guo CW, Kawakatsu M, Idemitsu M, Urata Y, Goto S, Ono Y, Hamano K, Li TS.  Culture under low physiological oxygen conditions improves the stemness and quality of induced pluripotent stem cells.  J Cell Physiol  2013  228(11):2159-66  PubMed ID: 23589166   DOI: 10.1002/jcp.24389
5723  Inagaki E, Hatou S, Yoshida S, Miyashita H, Tsubota K, Shimmura S.  Expression and distribution of claudin subtypes in human corneal endothelium.  Invest Ophthalmol Vis Sci  2013  54(12):7258-65  PubMed ID: 24114540   DOI: 10.1167/iovs.13-12022
13655  Ohta S, Imaizumi Y, Akamatsu W, Okano H, Kawakami Y.  Generation of human melanocytes from induced pluripotent stem cells  Methods Mol Biol  2013  989:193-215  PubMed ID: 23483397   DOI: 10.1007/978-1-62703-330-5_16
5702  Hayashi R, Ishikawa Y, Ito M, Kageyama T, Takashiba K, Fujioka T, Tsujikawa M, Miyoshi H, Yamato M, Nakamura Y, Nishida K.  Generation of corneal epithelial cells from induced pluripotent stem cells derived from human dermal fibroblast and corneal limbal epithelium.  PLoS One  2012  7(9):e45435  PubMed ID: 23029008   DOI: 10.1371/journal.pone.0045435
5703  Hasehira K, Tateno H, Onuma Y, Ito Y, Asashima M, Hirabayashi J.  Structural and quantitative evidence for dynamic glycome shift on production of induced pluripotent stem cells.  Mol Cell Proteomics  2012  11(12):1913-23  PubMed ID: 23023295   DOI: 10.1074/mcp.M112.020586
5704  Kuroda T, Yasuda S, Kusakawa S, Hirata N, Kanda Y, Suzuki K, Takahashi M, Nishikawa S, Kawamata S, Sato Y.  Highly sensitive in vitro methods for detection of residual undifferentiated cells in retinal pigment epithelial cells derived from human iPS cells.  PLoS One  2012  7(5):e37342  PubMed ID: 22615985   DOI: 10.1371/journal.pone.0037342
5706  Otsuji TG, Kurose Y, Suemori H, Tada M, Nakatsuji N.  Dynamic link between histone H3 acetylation and an increase in the functional characteristics of human ESC/iPSC-derived cardiomyocytes.  PLoS One  2012  7(9):e45010  PubMed ID: 22984602   DOI: 10.1371/journal.pone.0045010
5721  Shofuda T, Kanematsu D, Fukusumi H, Yamamoto A, Bamba Y, Yoshitatsu S, Suemizu H, Nakamura M, Sugimoto Y, Furue MK, Kohara A, Akamatsu W, Okada Y, Okano H, Yamasaki M, Kanemura Y.  Human Decidua-Derived Mesenchymal Cells Are a Promising Source for the Generation and Cell Banking of Human Induced Pluripotent Stem Cells.  Cell Med  2012  4(3):125-47  PubMed ID: 26858858   DOI: 10.3727/215517912X658918
7771  Ogawa S, Tokumoto Y, Miyake J, Nagamune T.  Induction of oligodendrocyte differentiation from adult human fibroblast-derived induced pluripotent stem cells.  In Vitro Cell. Dev. Biol. Anim.  2011  47:464-9  PubMed ID: 21695581   DOI: 10.1007/s11626-011-9435-2
5698  Tomizawa M, Shinozaki F, Sugiyama T, Yamamoto S, Sueishi M, Yoshida T.  Activin A maintains pluripotency markers and proliferative potential of human induced pluripotent stem cells.  Exp Ther Med  2011  2(3):405-408  PubMed ID: 22977517   DOI: 10.3892/etm.2011.219
5750  Kumazaki T, Kurata S, Matsuo T, Mitsui Y, Takahashi T.  Establishment of human induced pluripotent stem cell lines from normal fibroblast TIG-1.  Hum Cell  2011  24(2):96-103  PubMed ID: 21562774   DOI: 10.1007/s13577-011-0016-1
5699  Nishi M, Akutsu H, Masui S, Kondo A, Nagashima Y, Kimura H, Perrem K, Shigeri Y, Toyoda M, Okayama A, Hirano H, Umezawa A, Yamamoto N, Lee SW, Ryo A.  A distinct role for Pin1 in the induction and maintenance of pluripotency.  J Biol Chem  2011  286(13):11593-603  PubMed ID: 21296877   DOI: 10.1074/jbc.M110.187989
5700  Yoshizaki S, Nishi M, Kondo A, Kojima Y, Yamamoto N, Ryo A.  Vaccination with Human Induced Pluripotent Stem Cells Creates an Antigen-Specific Immune Response Against HIV-1 gp160.  Front Microbiol  2011  2:27  PubMed ID: 21687419   DOI: 10.3389/fmicb.2011.00004

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4523  大貫 喜嗣 他  CHIR99021 が維持培養期間中のヒト iPS 細胞の増殖性および分化方向性に及ぼす影響  組織培養研究  2017  6, S25-S26    DOI: 10.11418/jtca.36.S25
10878  Yoshitsugu Ohnuki, Hiroshi Kurosa  ヒト iPS 細胞の分化誘導プロセスにおける細胞の構造構築段階の重要性  THE CHEMICAL TIMES  2016  241:12-16   



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