Cell No. : Cell Name RCB6054 : ARE-Luc MEF  update : 2025/02/05
Comment			Currently not ready.
Comment from the depositor			Mouse embryonic fibroblasts expressing a luciferase reporter under the control of the antioxidant response element (ARE) derived from the mouse NQO1 gene. These cells were established from Nqo1-ARE-Luc transgenic mice (PMID: 17237276). Luciferase activity allows the evaluation of ARE-dependent transcriptional activation.
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	Basic information	Expected time	Upon a request we will start preparation. Contact us: cellkitaku.brc@riken.jp
Reference information		Reference	2
		User's Publication	0

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Reference

22504  Hirotsu Y, Katsuoka F, Itoh K, Yamamoto M.  Nrf2 degron-fused reporter system: a new tool for specific evaluation of Nrf2 inducers.  Genes Cells  2011  16(4):406-15  PubMed ID: 21392184   DOI: 10.1111/j.1365-2443.2011.01496.x

22505  Yates MS, Tauchi M, Katsuoka F, Flanders KC, Liby KT, Honda T, Gribble GW, Johnson DA, Johnson JA, Burton NC, Guilarte TR, Yamamoto M, Sporn MB, Kensler TW.  Pharmacodynamic characterization of chemopreventive triterpenoids as exceptionally potent inducers of Nrf2-regulated genes.  Mol Cancer Ther  2007  6(1):154-62  PubMed ID: 17237276   DOI: 10.1158/1535-7163.MCT-06-0516

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