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Cell No. : Cell Name
RCB5962 : HUDEP-2-CY1  update : 2024/10/11
CommentCurrently not ready.
Comment from the depositorA derivative cell line of HUDEP-2 in which thalassemia mutations are introduced, i.e., homozygous for the HBB IVSI-110 (G>A) mutation (HGVS name; HBB:c.93-21G>A).
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Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
Basic information Expected time Upon a request we will start preparation. Contact us: cellkitaku.brc@riken.jp
IPR The Cyprus Foundation for Muscular Dystrophy Research (Cyprus) & RIKEN BioResource Research Center (Japan)
Reference information Reference 3
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Reference
18128  Papaioannou NY, Patsali P, Naiisseh B, Papasavva PL, Koniali L, Kurita R, Nakamura Y, Christou S, Sitarou M, Mussolino C, Cathomen T, Kleanthous M, Lederer CW.  High-efficiency editing in hematopoietic stem cells and the HUDEP-2 cell line based on in vitro mRNA synthesis  Front Genome Ed  2023  5:1141618  PubMed ID: 36969374   DOI: 10.3389/fgeed.2023.1141618
18129  Papasavva P, Kleanthous M, Lederer CW.  Rare Opportunities: CRISPR/Cas-Based Therapy Development for Rare Genetic Diseases  Mol Diagn Ther  2019  23(2):201-222  PubMed ID: 30945166   DOI: 10.1007/s40291-019-00392-3
6742  Kurita R, Suda N, Sudo K, Miharada K, Hiroyama T, Miyoshi H, Tani K, Nakamura Y.  Establishment of immortalized human erythroid progenitor cell lines able to produce enucleated red blood cells.  PLoS One  2013  8(3):e59890  PubMed ID: 23533656   DOI: 10.1371/journal.pone.0059890

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