Cell No. : Cell Name
RCB5479 : hFGFR2c/BaF3
update : 2022/09/06
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| Comment | Currently not ready. |
| Comment from the depositor | The FGF receptor-overexpressing cells to be used for the analyses of receptor specificity of the various FGF ligands. These cells are engineered from Ba/F3 cells and stably overexpress one of seven subtypes, as defined in the cell name, of FGF receptors. When a cognate (specific) FGF ligand is added, together with heparin, to the medium of these cells, cell growth is stimulated that can be detected by cell number and/or DNA synthesis. While the parent Ba/F3 cells proliferate only by the stimulation with IL-3. |
| Terms and conditions | |
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| Order Form |
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Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
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Basic information
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Expected time |
Upon a request we will start preparation. Contact us: cellkitaku.brc@riken.jp
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| Reference information |
Reference |
2
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| User's Publication |
0
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| Reference |
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16423
Nakamura M, Uehara Y, Asada M, Suzuki M, Imamura T.
Sulfated glycosaminoglycan-assisted receptor specificity of human fibroblast growth factor (FGF) 19 signaling in a mouse system is different from that in a human system
J Biomol Screen
2013
18(3):321-30
PubMed ID: 23064887
DOI: 10.1177/1087057112463820
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16422
Nakamura M, Uehara Y, Asada M, Honda E, Nagai N, Kimata K, Suzuki M, Imamura T.
Sulfated glycosaminoglycans are required for specific and sensitive fibroblast growth factor (FGF) 19 signaling via FGF receptor 4 and betaKlotho
J Biol Chem
2011
286(30):26418-23
PubMed ID: 21653700
DOI: 10.1074/jbc.M111.251140
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