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Cell No. : Cell Name
RCB5350 : XRCC1,XPA-TK6  update : 2022/09/06
CommentCurrently not ready.
Comment from the depositorTK6 cells are one of the most commonly used human B lymphocyte-derived cell for cancer research. XRCC1, XPA- disrupted TK6 cells.
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Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
Basic information Expected time Upon a request we will start preparation. Contact us: cellkitaku.brc@riken.jp
Reference information Reference 6
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Reference
17833  Sassa A, Fukuda T, Ukai A, Nakamura M, Sato R, Fujiwara S, Hirota K, Takeda S, Sugiyama KI, Honma M, Yasui M.  Follow-up genotoxicity assessment of Ames-positive/equivocal chemicals using the improved thymidine kinase gene mutation assay in DNA repair-deficient human TK6 cells  Mutagenesis  2021  36(5):331-338  PubMed ID: 34216473   DOI: 10.1093/mutage/geab025
17835  Ibrahim MA, Yasui M, Saha LK, Sasanuma H, Honma M, Takeda S.  Enhancing the sensitivity of the thymidine kinase assay by using DNA repair-deficient human TK6 cells  Environ Mol Mutagen  2020  61(6):602-610  PubMed ID: 32243652   DOI: 10.1002/em.22371
17852  Saha LK, Wakasugi M, Akter S, Prasad R, Wilson SH, Shimizu N, Sasanuma H, Huang SN, Agama K, Pommier Y, Matsunaga T, Hirota K, Iwai S, Nakazawa Y, Ogi T, Takeda S.  Topoisomerase I-driven repair of UV-induced damage in NER-deficient cells  Proc Natl Acad Sci U S A   2020  117(25):14412-14420  PubMed ID: 32513688   DOI: 10.1073/pnas.1920165117
279  Skopek TR, Liber HL, Penman BW, Thilly WG.  Isolation of a human lymphoblastoid line heterozygous at the thymidine kinase locus: possibility for a rapid human cell mutation assay  Biochem Biophys Res Commun  1978  84(2):411-6  PubMed ID: 214074   DOI: 10.1016/0006-291x(78)90185-7
281  Levy JA, Buell DN, Creech C, Hirshaut Y, Silverberg H.  Further characterization of the WI-L1 and WI-L2 lymphoblastoid lines  J Natl Cancer Inst  1971  46(3):647-54  PubMed ID: 4323138  
280  Levy JA, Virolainen M, Defendi V.  Human lymphoblastoid lines from lymph node and spleen  Cancer  1968  22(3):517-24  PubMed ID: 5673231   DOI: 10.1002/1097-0142(196809)22:3<517::aid-cncr2820220305>3.0.co;2-a

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