Cell No. : Cell Name RCB5349 : XRCC1-TK6  update : 2022/09/06
Comment			Currently not ready.
Comment from the depositor			TK6 cells are one of the most commonly used human B lymphocyte-derived cell for cancer research. XRCC1- disrupted TK6 cells.
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			Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
	Basic information	Expected time	Upon a request we will start preparation. Contact us: cellkitaku.brc@riken.jp
Reference information		Reference	7
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Reference

17847  Hirota K, Ooka M, Shimizu N, Yamada K, Tsuda M, Ibrahim MA, Yamada S, Sasanuma H, Masutani M, Takeda S.  XRCC1 counteracts poly(ADP ribose)polymerase (PARP) poisons, olaparib and talazoparib, and a clinical alkylating agent, temozolomide, by promoting the removal of trapped PARP1 from broken DNA  Genes Cells  2022  27(5):331-344  PubMed ID: 35194903   DOI: 10.1111/gtc.12929

17856  Li J, Beiser A, Dey NB, Takeda S, Saha LK, Hirota K, Parker LL, Carter M, Arrieta MI, Sobol RW.  A high-throughput 384-well CometChip platform reveals a role for 3-methyladenine in the cellular response to etoposide-induced DNA damage  NAR Genom Bioinform  2022  4(3):lqac065  PubMed ID: 36110898   DOI: 10.1093/nargab/lqac065

17850  Demin AA, Hirota K, Tsuda M, Adamowicz M, Hailstone R, Brazina J, Gittens W, Kalasova I, Shao Z, Zha S, Sasanuma H, Hanzlikova H, Takeda S, Caldecott KW.  XRCC1 prevents toxic PARP1 trapping during DNA base excision repair  Mol Cell  2021  81(14):3018-3030  PubMed ID: 34102106   DOI: 10.1016/j.molcel.2021.05.009

17852  Saha LK, Wakasugi M, Akter S, Prasad R, Wilson SH, Shimizu N, Sasanuma H, Huang SN, Agama K, Pommier Y, Matsunaga T, Hirota K, Iwai S, Nakazawa Y, Ogi T, Takeda S.  Topoisomerase I-driven repair of UV-induced damage in NER-deficient cells  Proc Natl Acad Sci U S A   2020  117(25):14412-14420  PubMed ID: 32513688   DOI: 10.1073/pnas.1920165117

279  Skopek TR, Liber HL, Penman BW, Thilly WG.  Isolation of a human lymphoblastoid line heterozygous at the thymidine kinase locus: possibility for a rapid human cell mutation assay  Biochem Biophys Res Commun  1978  84(2):411-6  PubMed ID: 214074   DOI: 10.1016/0006-291x(78)90185-7

281  Levy JA, Buell DN, Creech C, Hirshaut Y, Silverberg H.  Further characterization of the WI-L1 and WI-L2 lymphoblastoid lines  J Natl Cancer Inst  1971  46(3):647-54  PubMed ID: 4323138

280  Levy JA, Virolainen M, Defendi V.  Human lymphoblastoid lines from lymph node and spleen  Cancer  1968  22(3):517-24  PubMed ID: 5673231   DOI: 10.1002/1097-0142(196809)22:3<517::aid-cncr2820220305>3.0.co;2-a

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