Cell No. : Cell Name
RCB5349 : XRCC1-TK6
update : 2026/03/31
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| Comment | Currently not ready. |
| Comment from the depositor | TK6 cells are one of the most commonly used human B lymphocyte-derived cell for cancer research. XRCC1- disrupted TK6 cells. |
| Terms and conditions | BIOLOGICAL RESOURCE is limited to for academic researches in non-profit organization.
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| Remarks | CRISPR/Cas9 genome edited bioresources Announcement of bioresources developed by the CRISPR/Cas9 technology. |
| Order Form |
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Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
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Basic information
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Expected time |
Upon a request we will start preparation. Contact us: cellqa.brc@riken.jp
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| Reference information |
Reference |
8
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| User's Publication |
0
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| Reference |
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17847
Hirota K, Ooka M, Shimizu N, Yamada K, Tsuda M, Ibrahim MA, Yamada S, Sasanuma H, Masutani M, Takeda S.
XRCC1 counteracts poly(ADP ribose)polymerase (PARP) poisons, olaparib and talazoparib, and a clinical alkylating agent, temozolomide, by promoting the removal of trapped PARP1 from broken DNA
Genes Cells
2022
27(5):331-344
PubMed ID: 35194903
DOI: 10.1111/gtc.12929
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17856
Li J, Beiser A, Dey NB, Takeda S, Saha LK, Hirota K, Parker LL, Carter M, Arrieta MI, Sobol RW.
A high-throughput 384-well CometChip platform reveals a role for 3-methyladenine in the cellular response to etoposide-induced DNA damage
NAR Genom Bioinform
2022
4(3):lqac065
PubMed ID: 36110898
DOI: 10.1093/nargab/lqac065
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17850
Demin AA, Hirota K, Tsuda M, Adamowicz M, Hailstone R, Brazina J, Gittens W, Kalasova I, Shao Z, Zha S, Sasanuma H, Hanzlikova H, Takeda S, Caldecott KW.
XRCC1 prevents toxic PARP1 trapping during DNA base excision repair
Mol Cell
2021
81(14):3018-3030
PubMed ID: 34102106
DOI: 10.1016/j.molcel.2021.05.009
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17852
Saha LK, Wakasugi M, Akter S, Prasad R, Wilson SH, Shimizu N, Sasanuma H, Huang SN, Agama K, Pommier Y, Matsunaga T, Hirota K, Iwai S, Nakazawa Y, Ogi T, Takeda S.
Topoisomerase I-driven repair of UV-induced damage in NER-deficient cells
Proc Natl Acad Sci U S A
2020
117(25):14412-14420
PubMed ID: 32513688
DOI: 10.1073/pnas.1920165117
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2127
Gupta RS.
Diphtheria toxin resistance in human lymphoblast lines
Biochem Biophys Res Commun
1980
94(4):1303-10
PubMed ID: 7396963
DOI: 10.1016/0006-291x(80)90561-6
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279
Skopek TR, Liber HL, Penman BW, Thilly WG.
Isolation of a human lymphoblastoid line heterozygous at the thymidine kinase locus: possibility for a rapid human cell mutation assay
Biochem Biophys Res Commun
1978
84(2):411-6
PubMed ID: 214074
DOI: 10.1016/0006-291x(78)90185-7
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281
Levy JA, Buell DN, Creech C, Hirshaut Y, Silverberg H.
Further characterization of the WI-L1 and WI-L2 lymphoblastoid lines
J Natl Cancer Inst
1971
46(3):647-54
PubMed ID: 4323138
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280
Levy JA, Virolainen M, Defendi V.
Human lymphoblastoid lines from lymph node and spleen
Cancer
1968
22(3):517-24
PubMed ID: 5673231
DOI: 10.1002/1097-0142(196809)22:3<517::aid-cncr2820220305>3.0.co;2-a
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