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Cell No. : Cell Name
RCB5313 : NP-2/CD4/EcoVR/RDC1  update : 2023/10/16
CommentCurrently not ready.
Comment from the depositorNP-2 is derived from a human glioma cell line. NP-2/CD4/EcoVR/RDC1 (NP-2/CD4/RDC1) cells are transduced with human CD4, ecotropic mouse retrovirus receptor and humanRDC1 genes and expressing cells were cloned. Although NP-2/CD4/EcoVR cell is resistant to HIVs, NP-2/CD4/EcoVR/RDC1 cells become highly susceptible to HIVs that use RDC1 as a coreceptor.
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Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
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Reference
2126  Hiroo Hoshino  The NP-2 Cell System for Analyses of the Coreceptor Usage of Human and Simian Immunodeficiency Viruses  The Kitakanto Medical Journal  2012  62:1-14    DOI: 10.2974/kmj.62.1
12350  N Shimizu, Y Soda, K Kanbe, H Y Liu, R Mukai, T Kitamura, H Hoshino  A putative G protein-coupled receptor, RDC1, is a novel coreceptor for human and simian immunodeficiency viruses  J Virol  2000  74(2):619-26  PubMed ID: 10623723   DOI: 10.1128/jvi.74.2.619-626.2000

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