Cell No. : Cell Name RCB5309 : NP-2/CD4/EcoVR/CCR6  update : 2024/05/07
Comment			Currently not ready.
Comment from the depositor			NP-2 is derived from a human glioma cell line. NP-2/CD4/EcoVR/CCR6 (NP-2/CD4/CCR6) cells are transduced with human CD4, ecotropic mouse retrovirus receptor and human CCR6 genes and expressing cells were cloned. Although NP-2/CD4/EcoVR cell is resistant to HIVs, NP-2/CD4/EcoVR/CCR6 cells become highly susceptible to HIVs that use CCR6 as a coreceptor.
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			Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
	Basic information	Expected time	Upon a request we will start preparation. Contact us: cellkitaku.brc@riken.jp
		Cellosaurus(Expasy)	CVCL_A6UR
Reference information		Reference	2
		User's Publication	0

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Reference

2126  Hiroo Hoshino  The NP-2 Cell System for Analyses of the Coreceptor Usage of Human and Simian Immunodeficiency Viruses  The Kitakanto Medical Journal  2012  62:1-14    DOI: 10.2974/kmj.62.1

12273  Y Soda, N Shimizu, A Jinno, H Y Liu, K Kanbe, T Kitamura, H Hoshino  Establishment of a new system for determination of coreceptor usages of HIV based on the human glioma NP-2 cell line  Biochem Biophys Res Commun  1999  258(2):313-21  PubMed ID: 10329384   DOI: 10.1006/bbrc.1999.0633

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