Cell No. : Cell Name
RCB5263 : ATL-1K
update : 2024/04/19
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| Comment | |
| Comment from the depositor | ATL-1K is a cell line established from peripheral blood of a patient with adult T-cell leukemia (ATL) and can grow without IL-2. ATL-1K cells contain one copy of HTLV-1 proviral DNA per cell. The expression of HTLV-1 antigen is not detected. |
| Terms and conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature (Proc Natl Acad Sci U S A 1983 80(19):6061-5) designated by the DEPOSITOR is requested.
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| Remarks | |
| Order Form |
Order Form(C-0005.pdf)
MTA(C-0007.pdf)
MTA(C-0007p.pdf)
Cell line to be handled at BSL 2(C-0070.pdf)
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Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
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Basic information
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Depositor |
OUE, Atsushi
|
| Originator |
HOSHINO, Hiroo
|
| Year of deposit |
2019
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| Animal |
_human
< Mammals
|
| Genus |
Homo
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| Species |
sapiens
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| Race |
Japanese
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| Gender |
Male
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| Age at sampling |
82 years
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| Tissue |
blood
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| Disease name |
adult T-cell leukemia (ATL)
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| Classification |
cancer
|
|
Lifespan |
infinite
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| Morphology |
lymphocyte-like
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| Surface antigen (depositor) |
CD4(+), CD3(-), CD8(-)
|
| BSL |
BSL2
|
| Cellosaurus(Expasy) |
CVCL_A406
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deposit info |
lot info |
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Medium |
Medium List |
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Culture type |
Suspension cells
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Suspension cells
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| Culture medium |
RPMI-1640 + 20% heat-inactivated fetal calf serum
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RPMI1640 + 20% FBS (heat inactivated)
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| Culture method |
|
|
| Antibiotics |
100units/ml Penicillin G、100μg/ml Streptomycin
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Free
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Passage method |
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dilution
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Culture information
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Passage ratio |
|
1 : 5-10 split
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| SC frequency |
Subculture: 2times/week
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Subculture: 2times/week
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| Temperature |
37
℃
|
37
℃
|
| CO2 concentration |
5
%
|
5
%
|
| Freeze medium |
Medium + 10% DMSO
|
Medium + 10% DMSO
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| Freezing method |
|
Slow freezing
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| Mycoplasma |
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(-)
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| Animal PCR |
|
OK
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| Virus (HIV) |
|
Undetected
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| Virus (HTLV-1) |
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DNA (+)
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| Virus (EBV) |
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(-)
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| STR(human) |
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OK
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deposit info
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lot info
|
| D5S818 |
D13S317 |
D7S820 |
D16S539 |
vWA |
TH01 |
Amelogenin |
TPOX |
CSF1PO |
|
10,12
|
8
|
11
|
11,12
|
16,18
|
9
|
X
|
8,11
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12
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| Reference information |
Reference |
14
|
| User's Publication |
0
|
| Reference |
|
10644
Shimizu A, Nakatani Y, Nakamura T, Jinno-Oue A, Ishikawa O, Boeke JD, Takeuchi Y, Hoshino H.
Characterisation of cytoplasmic DNA complementary to non-retroviral RNA viruses in human cells
Sci Rep
2014
4:5074
PubMed ID: 24875540
DOI: 10.1038/srep05074
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6155
Islam S, Hoque SA, Adnan N, Tanaka A, Jinno-Oue A, Hoshino H.
X4-tropic human immunodeficiency virus IIIB utilizes CXCR4 as coreceptor, as distinct from R5X4-tropic viruses
Microbiol Immunol
2013
57(6):437-44
PubMed ID: 23773022
DOI: 10.1111/1348-0421.12051
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2448
Nitta T, Tanaka M, Sun B, Hanai S, Miwa M.
The genetic background as a determinant of human T-cell leukemia virus type 1 proviral load
Biochem Biophys Res Commun
2003
309(1):161-5
PubMed ID: 12943677
DOI: 10.1016/s0006-291x(03)01543-2
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2450
Feng R, Tanaka M, Abe H, Arashi N, Sun B, Uchida K, Miwa M.
Human T-cell leukemia virus type 1 can infect a wide variety of cells in mice
Jpn J Cancer Res
1999
90(1):48-54
PubMed ID: 10076564
DOI: 10.1111/j.1349-7006.1999.tb00664.x
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2455
Hsu DK, Hammes SR, Kuwabara I, Greene WC, Liu FT.
Human T lymphotropic virus-I infection of human T lymphocytes induces expression of the beta-galactoside-binding lectin, galectin-3
Am J Pathol
1996
148(5):1661-70.
PubMed ID: 8623933
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2447
Hori M, Ami Y, Kushida S, Kobayashi M, Uchida K, Abe T, Miwa M.
Intrauterine transmission of human T-cell leukemia virus type I in rats
J Virol
1995
69(2):1302-5
PubMed ID: 7815510
DOI: 10.1128/JVI.69.2.1302-1305.1995
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2707
Kinoshita T, Imamura J, Nagai H, Shimotohno K.
Quantification of gene expression over a wide range by the polymerase chain reaction
Anal Biochem
1992
206(2):231-5
PubMed ID: 1280006
DOI: 10.1016/0003-2697(92)90358-e
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2449
Nyborg JK, Matthews MA, Yucel J, Walls L, Golde WT, Dynan WS, Wachsman W.
Interaction of host cell proteins with the human T-cell leukemia virus type I transcriptional control region. II. A comprehensive map of protein-binding sites facilitates construction of a simple chimeric promoter responsive to the viral tax2 gene product
J Biol Chem
1990
265(14):8237-42
PubMed ID: 2186038
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2569
Kinoshita T, Shimoyama M, Tobinai K, Ito M, Ito S, Ikeda S, Tajima K, Shimotohno K, Sugimura T.
Detection of mRNA for the tax1/rex1 gene of human T-cell leukemia virus type I in fresh peripheral blood mononuclear cells of adult T-cell leukemia patients and viral carriers by using the polymerase chain reaction
Proc Natl Acad Sci U S A
1989
86(14):5620-4
PubMed ID: 2787512
DOI: 10.1073/pnas.86.14.5620
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2589
Kai C, Okada N, Okada H.
Expression of CR2 (C3d receptor) on the cell membranes of adult T cell leukemia
Jpn J Cancer Res
1988
79(7):805-8
PubMed ID: 2971638
DOI: 10.1111/j.1349-7006.1988.tb00039.x
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3853
Suzuki Y, Hirabayashi Y, Matsumoto N, Kato H, Hidari K, Tsuchiya K, Matsumoto M, Hoshino H, Tozawa H, Miwa M.
Aberrant expression of ganglioside and asialoglycosphingolipid antigens in adult T-cell leukemia cells
Jpn J Cancer Res
1987
78(10):1112-20
PubMed ID: 2890614
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2609
Hoshino H, Shimizu N, Shimada N, Takita T, Takeuchi T.
Inhibition of infectivity of human immunodeficiency virus by oxetanocin
J Antibiot (Tokyo)
1987
40(7):1077-8
PubMed ID: 3650259
DOI: 10.7164/antibiotics.40.1077
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3521
H Hoshino, H Esumi, M Miwa, M Shimoyama, K Minato, K Tobinai, M Hirose, S Watanabe, N Inada, K Kinoshita, S Kamihira, M Ichimaru, T Sugimura
Establishment and characterization of 10 cell lines derived from patients with adult T-cell leukemia
Proc Natl Acad Sci U S A
1983
80(19):6061-5
PubMed ID: 6193528
DOI: 10.1073/pnas.80.19.6061
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3912
Hoshino H, Shimoyama M, Miwa M, Sugimura T.
Detection of lymphocytes producing a human retrovirus associated with adult T-cell leukemia by syncytia induction assay
Proc Natl Acad Sci U S A
1983
80(23):7337-41
PubMed ID: 6316359
DOI: 10.1073/pnas.80.23.7337
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