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Cell No. : Cell Name
RCB4699 : S-TFE  update : 2024/11/11
Comment
Comment from the depositorS-TFE is established from a rare subtype of Xp11 translocation renal cell carcinoma. The cell line demonstrated definite gene fusion including TFE3 gene located on chromosome X. It showed ASPL-TFE3 type 1 fusion.
Terms and conditionsIn publishing research results obtained by the use of the BIOLOGICAL RESOURCE, a citation of the literature ref. (Cancer Biol Ther. 2013;14(6):502-10) designated by the DEPOSITOR is required.
Remarks
Order Form Order Form(C-0005.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)  
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
Basic information Depositor MASUMORI, Naoya
Originator HIROBE, Megumi
Year of deposit 2017
Cloning (depositor) No
Animal _human < Mammals
Genus Homo
Species sapiens
Gender Female
Age at sampling 18 years
Tissue Left kidney
Disease name left renal tumor
Tumor pT3aN2MX
Metastatic ability No
Classification cancer
Recombinant non-recombinant
Year of origin 2009
Lifespan infinite
Morphology epithelial-like
Cellosaurus(Expasy) CVCL_R854
deposit info
lot info
Medium Medium List
Culture type Adherent cells Adherent cells
Culture medium RPMI1640+10%FBS RPMI1640 + 10%FBS
Antibiotics 100U/m penicillin, 100μg/ml streptomycin Free
Passage method T-EDTA 0.25% Trypsin + (0.02% EDTA or 0.04% EDTA)
Culture information Passage ratio 1 : 2-3 split
SC frequency Subculture : once/7-10 days, Medium Renewal : 2 times/week
Temperature 37 ℃ 37 ℃
CO2 concentration 5 % 5 %
Freeze medium CELLBANKER CELLBANKER 1
Freezing method Slow freezing
Mycoplasma/Acholeplasma (-)
Animal PCR OK
STR(human) OK
deposit info
lot info
D5S818 D13S317 D7S820 D16S539 vWA TH01 Amelogenin TPOX CSF1PO
9,11 8,11 12 11,12 16,17 6,7 X 8 10
Reference information Reference 1
User's Publication 3


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Reference
7613  Hirobe M, Masumori N, Tanaka T, Kitamura H, Tsukamoto T.  Establishment of an ASPL-TFE3 renal cell carcinoma cell line (S-TFE).  Cancer Biol Ther  2013  14(6):502-10  PubMed ID: 23760492   DOI: 10.4161/cbt.24344

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User's Publication
21945  Achom M, Sadagopan A, Bao C, McBride F, Li J, Konda P, Tourdot RW, Xu Q, Nakhoul M, Gallant DS, Ahmed UA, O'Toole J, Freeman D, Lee GM, Hecht JL, Kauffman EC, Einstein DJ, Choueiri TK, Zhang CZ, Viswanathan SR.  A genetic basis for sex differences in Xp11 translocation renal cell carcinoma.  Cell  2024    PubMed ID: 39168126   DOI: 10.1016/j.cell.2024.07.038
21093  Takamatsu D, Kohashi K, Kiyozawa D, Kinoshita F, Ieiri K, Baba M, Eto M, Oda Y.  TFE3-immunopositive papillary renal cell carcinoma: A clinicopathological, immunohistochemical, and genetic study.  Pathol Res Pract  2023  242:154313  PubMed ID: 36669395   DOI: 10.1016/j.prp.2023.154313
16507  Park JS, Lee ME, Jang WS, Kim J, Park SM, Ham WS.  Gene Expression Analysis of Aggressive Adult Xp11.2 Translocation Renal Cell Carcinoma at Clinical Stage T1N0M0 to Identify Potential Prognostic and Therapeutic Biomarkers  Biomedicines  2022  10(2):321  PubMed ID: 35203530   DOI: 10.3390/biomedicines10020321



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