Cell No. : Cell Name
RCB4699 : S-TFE
update : 2025/03/03
|
| Comment | |
| Comment from the depositor | S-TFE is established from a rare subtype of Xp11 translocation renal cell carcinoma. The cell line demonstrated definite gene fusion including TFE3 gene located on chromosome X. It showed ASPL-TFE3 type 1 fusion. |
| Terms and conditions | In publishing research results obtained by the use of the BIOLOGICAL RESOURCE, a citation of the literature ref. (Cancer Biol Ther. 2013;14(6):502-10) designated by the DEPOSITOR is required. |
| Remarks | |
| Order Form |
Order Form(C-0005.pdf)
MTA(C-0007.pdf)
MTA(C-0007p.pdf)
|
|
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
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Basic information
|
Depositor |
MASUMORI, Naoya
|
| Originator |
HIROBE, Megumi
|
| Year of deposit |
2017
|
| Cloning (depositor) |
No
|
| Animal |
_human
< Mammals
|
| Genus |
Homo
|
| Species |
sapiens
|
| Gender |
Female
|
| Age at sampling |
18 years
|
| Tissue |
Left kidney
|
| Disease name |
left renal tumor
|
| Tumor |
pT3aN2MX
|
| Metastatic ability |
No
|
| Classification |
cancer
|
| Recombinant |
non-recombinant
|
| Year of origin |
2009
|
|
Lifespan |
infinite
|
| Morphology |
epithelial-like
|
| Cellosaurus(Expasy) |
CVCL_R854
|
|
| |
deposit info |
lot info |
|
Medium |
Medium List |
|
Culture type |
Adherent cells
|
Adherent cells
|
| Culture medium |
RPMI1640+10%FBS
|
RPMI1640 + 10%FBS
|
| Antibiotics |
100U/m penicillin, 100μg/ml streptomycin
|
Free
|
|
Passage method |
T-EDTA
|
0.25% Trypsin + (0.02% EDTA or 0.04% EDTA)
|
Culture information
|
Passage ratio |
|
1 : 2-3 split
|
| SC frequency |
|
Subculture : once/7-10 days, Medium Renewal : 2 times/week
|
| Temperature |
37
℃
|
37
℃
|
| CO2 concentration |
5
%
|
5
%
|
| Freeze medium |
CELLBANKER
|
CELLBANKER 1
|
| Freezing method |
|
Slow freezing
|
| Mycoplasma/Acholeplasma |
|
(-)
|
| Animal PCR |
|
OK
|
| STR(human) |
|
OK
|
|
deposit info
|
|
|
lot info
|
| D5S818 |
D13S317 |
D7S820 |
D16S539 |
vWA |
TH01 |
Amelogenin |
TPOX |
CSF1PO |
|
9,11
|
8,11
|
12
|
11,12
|
16,17
|
6,7
|
X
|
8
|
10
|
|
| Reference information |
Reference |
1
|
| User's Publication |
4
|
| User's Publication |
|
23317
Li J, Huang K, Thakur M, McBride F, Sadagopan A, Gallant DS, Khanna P, Laimon YN, Li B, Mohanna R, Ge M, Weiss CN, Achom M, Xu Q, Matar S, Lee GM, Huang K, Gui M, Wu CL, Cornejo KM, Choueiri TK, Ryback BA, Signoretti S, Bar-Peled L, Viswanathan SR.
Oncogenic TFE3 fusions drive OXPHOS and confer metabolic vulnerabilities in translocation renal cell carcinoma
Nat Metab
2025
7(3):478-492
PubMed ID: 39915638
DOI: 10.1038/s42255-025-01218-9
|
|
21945
Achom M, Sadagopan A, Bao C, McBride F, Li J, Konda P, Tourdot RW, Xu Q, Nakhoul M, Gallant DS, Ahmed UA, O'Toole J, Freeman D, Lee GM, Hecht JL, Kauffman EC, Einstein DJ, Choueiri TK, Zhang CZ, Viswanathan SR.
A genetic basis for sex differences in Xp11 translocation renal cell carcinoma.
Cell
2024
PubMed ID: 39168126
DOI: 10.1016/j.cell.2024.07.038
|
|
21093
Takamatsu D, Kohashi K, Kiyozawa D, Kinoshita F, Ieiri K, Baba M, Eto M, Oda Y.
TFE3-immunopositive papillary renal cell carcinoma: A clinicopathological, immunohistochemical, and genetic study.
Pathol Res Pract
2023
242:154313
PubMed ID: 36669395
DOI: 10.1016/j.prp.2023.154313
|
|
16507
Park JS, Lee ME, Jang WS, Kim J, Park SM, Ham WS.
Gene Expression Analysis of Aggressive Adult Xp11.2 Translocation Renal Cell Carcinoma at Clinical Stage T1N0M0 to Identify Potential Prognostic and Therapeutic Biomarkers
Biomedicines
2022
10(2):321
PubMed ID: 35203530
DOI: 10.3390/biomedicines10020321
|
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