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21677
Kim S, Lee Y, Song BR, Sim H, Kang EH, Hwang M, Yu N, Hong S, Park C, Ahn BC, Lim EJ, Hwang KH, Park SY, Choi JH, Lee GK, Han JY.
Drug Response of Patient-Derived Lung Cancer Cells Predicts Clinical Outcomes of Targeted Therapy.
Cancers (Basel)
2024
16(4)
PubMed ID: 38398169
DOI: 10.3390/cancers16040778
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21706
Ando S, Tanaka K, Matsumoto M, Oyama Y, Tomabechi Y, Yamagata A, Shirouzu M, Nakagawa R, Okimoto N, Taiji M, Sato K, Ohama T.
The luciferase-based in vivo protein-protein interaction assay revealed that CHK1 promotes PP2A and PME-1 interaction.
J Biol Chem
2024
107277
PubMed ID: 38588804
DOI: 10.1016/j.jbc.2024.107277
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21743
Zha L, Matsu-Ura T, Sluka JP, Murakawa T, Tsuta K.
Morphological basis of the lung adenocarcinoma subtypes.
iScience
2024
27(5):109742
PubMed ID: 38706836
DOI: 10.1016/j.isci.2024.109742
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21749
Kohsaka S, Yagishita S, Shirai Y, Matsuno Y, Ueno T, Kojima S, Ikeuchi H, Ikegami M, Kitada R, Yoshioka KI, Toshimitsu K, Tabata K, Yokoi A, Doi T, Yamamoto N, Owa T, Hamada A, Mano H.
A molecular glue RBM39-degrader induces synthetic lethality in cancer cells with homologous recombination repair deficiency.
NPJ Precis Oncol
2024
8(1):117
PubMed ID: 38789724
DOI: 10.1038/s41698-024-00610-0
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21840
Muneer G, Chen CS, Lee TT, Chen BY, Chen YJ.
A Rapid One-Pot Workflow for Sensitive Microscale Phosphoproteomics.
J Proteome Res
2024
PubMed ID: 39038167
DOI: 10.1021/acs.jproteome.3c00862
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21865
Matsui Y, Yamada T, Katayama Y, Hirai S, Sawada R, Tachibana Y, Ishida M, Kawachi H, Nakamura R, Nishioka N, Morimoto K, Iwasaku M, Horinaka M, Sakai T, Tokuda S, Takayama K.
Initial AXL and MCL-1 inhibition contributes to abolishing lazertinib tolerance in EGFR-mutant lung cancer cells
Cancer Sci
2024
Jul 22
PubMed ID: 39039802
DOI: 10.1111/cas.16292
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21873
Nakamura R, Yamada T, Tokuda S, Morimoto K, Katayama Y, Matsui Y, Hirai S, Ishida M, Kawachi H, Sawada R, Tachibana Y, Osoegawa A, Horinaka M, Sakai T, Yasuhiro T, Kozaki R, Yano S, Takayama K.
Triple combination therapy comprising osimertinib, an AXL inhibitor, and an FGFR inhibitor improves the efficacy of EGFR-mutated non-small cell lung cancer.
Cancer Lett
2024
598:217124
PubMed ID: 39059573
DOI: 10.1016/j.canlet.2024.217124
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17817
Ohkawa Y, Kitano M, Maeda K, Nakano M, Kanto N, Kizuka Y, Seike M, Azuma A, Yamaguchi Y, Ookawara T, Miyoshi E, Taniguchi N.
Core Fucosylation Is Required for the Secretion of and the Enzymatic Activity of SOD3 in Nonsmall-Cell Lung Cancer Cells
Antioxid Redox Signal
2023
Mar 6
PubMed ID: 36606688
DOI: 10.1089/ars.2022.0010
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19676
Clark IC, Fontanez KM, Meltzer RH, Xue Y, Hayford C, May-Zhang A, D'Amato C, Osman A, Zhang JQ, Hettige P, Ishibashi JSA, Delley CL, Weisgerber DW, Replogle JM, Jost M, Phong KT, Kennedy VE, Peretz CAC, Kim EA, Song S, Karlon W, Weissman JS, Smith CC, Gartner ZJ, Abate AR.
Microfluidics-free single-cell genomics with templated emulsification
Nat Biotechnol
2023
41(11):1557-1566
PubMed ID: 36879006
DOI: 10.1038/s41587-023-01685-z
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19697
Nakamura R, Fujii H, Yamada T, Matsui Y, Yaoi T, Honda M, Tanaka N, Miyagawa-Hayashino A, Yoshimura A, Morimoto K, Iwasaku M, Tokuda S, Kim YH, Konishi E, Itoh K, Takayama K.
Analysis of Tumor Heterogeneity Through AXL Activation in Primary Resistance to EGFR Tyrosine Kinase Inhibitors
JTO Clin Res Rep
2023
4(6):100525
PubMed ID: 37426308
DOI: 10.1016/j.jtocrr.2023.100525
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19731
Kosai K, Masuda T, Kitagawa A, Tobo T, Ono Y, Ando Y, Takahashi J, Haratake N, Kohno M, Takenaka T, Yoshizumi T, Mimori K.
Transducin Beta-Like 2 is a Potential Driver Gene that Adapts to Endoplasmic Reticulum Stress to Promote Tumor Growth of Lung Adenocarcinoma
Ann Surg Oncol
2023
30(12):7538-7548
PubMed ID: 37477745
DOI: 10.1245/s10434-023-13864-y
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19976
Gunasekaran P, Hwang YS, Lee GH, Park J, Kim JG, La YK, Park NY, Kothandaraman R, Yim MS, Choi J, Kim HN, Park IY, Lee SJ, Kim MH, Cha-Molstad H, Shin SY, Ryu EK, Bang JK.
Degradation of Polo-like Kinase 1 by the Novel Poly-Arginine N-Degron Pathway PROTAC Regulates Tumor Growth in Nonsmall Cell Lung Cancer
J Med Chem
2023
Dec 17
PubMed ID: 38105611
DOI: 10.1021/acs.jmedchem.3c01493
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20946
Takumi Y, Arai S, Suzuki C, Fukuda K, Nishiyama A, Takeuchi S, Sato H, Matsumoto K, Sugio K, Yano S.
MET kinase inhibitor reverses resistance to entrectinib induced by hepatocyte growth factor in tumors with NTRK1 or ROS1 rearrangements.
Cancer Med
2023
12(5):5809-5820
PubMed ID: 36416133
DOI: 10.1002/cam4.5342
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21119
Tokumo K, Masuda T, Nakashima T, Namba M, Yamaguchi K, Sakamoto S, Horimasu Y, Miyamoto S, Iwamoto H, Fujitaka K, Miyata Y, Okada M, Hamada H, Hattori N.
Association between Plasminogen Activator Inhibitor-1 and Osimertinib Tolerance in EGFR-Mutated Lung Cancer via Epithelial-Mesenchymal Transition.
Cancers (Basel)
2023
15(4)
PubMed ID: 36831438
DOI: 10.3390/cancers15041092
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21131
Konishi H, Haga Y, Lin Y, Tsujino H, Higashisaka K, Tsutsumi Y.
Osimertinib-tolerant lung cancer cells are susceptible to ferroptosis.
Biochem Biophys Res Commun
2023
641:116-122
PubMed ID: 36527745
DOI: 10.1016/j.bbrc.2022.12.029
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21136
Sumimoto H, Takano A, Igarashi T, Hanaoka J, Teramoto K, Daigo Y.
Oncogenic epidermal growth factor receptor signal-induced histone deacetylation suppresses chemokine gene expression in human lung adenocarcinoma.
Sci Rep
2023
13(1):5087
PubMed ID: 36991099
DOI: 10.1038/s41598-023-32177-4
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21224
Kim M, Kim S, Yim J, Keam B, Kim TM, Jeon YK, Kim DW, Heo DS.
Targeting CD73 to Overcomes Resistance to First-Generation EGFR Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer.
Cancer Res Treat
2023
PubMed ID: 37218137
DOI: 10.4143/crt.2023.311
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17574
Suzuki C, Nishiyama A, Arai S, Tange S, Tajima A, Tanimoto A, Fukuda K, Takumi Y, Kotani H, Takeuchi S, Yanagimura N, Ohtsubo K, Yamamoto N, Omori K, Yano S.
Inhibition of EGFR and MEK surmounts entrectinib resistance in a brain metastasis model of NTRK1-rearranged tumor cells
Cancer Sci
2022
113(7):2323-2335
PubMed ID: 35363931
DOI: 10.1111/cas.15354
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20516
Fan D, Yang Y, Zhang W.
A novel circ_MACF1/miR-942-5p/TGFBR2 axis regulates the functional behaviors and drug sensitivity in gefitinib-resistant non-small cell lung cancer cells.
BMC Pulm Med
2022
22(1):27
PubMed ID: 34996416
DOI: 10.1186/s12890-021-01731-z
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20523
Gebreyesus ST, Siyal AA, Kitata RB, Chen ES, Enkhbayar B, Angata T, Lin KI, Chen YJ, Tu HL.
Streamlined single-cell proteomics by an integrated microfluidic chip and data-independent acquisition mass spectrometry.
Nat Commun
2022
13(1):37
PubMed ID: 35013269
DOI: 10.1038/s41467-021-27778-4
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20529
Katayama Y, Yamada T, Tokuda S, Okura N, Nishioka N, Morimoto K, Tanimura K, Morimoto Y, Iwasaku M, Horinaka M, Sakai T, Kita K, Yano S, Takayama K.
Heterogeneity among tumors with acquired resistance to EGFR tyrosine kinase inhibitors harboring EGFR-T790M mutation in non-small cell lung cancer cells.
Cancer Med
2022
11(4):944-955
PubMed ID: 35029047
DOI: 10.1002/cam4.4504
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20595
Matsushige T, Sakabe T, Umekita Y.
Investigation of the Subcellular Localization-Dependent Anti- or Pro-Tumor Functions of Maspin in Human Lung Adenocarcinoma Cell Line.
Yonago Acta Med
2022
65(1):44-52
PubMed ID: 35221759
DOI: 10.33160/yam.2022.02.006
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16503
Tsuchiya K, Yoshimura K, Iwashita Y, Inoue Y, Ohta T, Watanabe H, Yamada H, Kawase A, Tanahashi M, Ogawa H, Funai K, Shinmura K, Suda T, Sugimura H.
m 6 A demethylase ALKBH5 promotes tumor cell proliferation by destabilizing IGF2BPs target genes and worsens the prognosis of patients with non-small-cell lung cancer
Cancer Gene Ther
2022
Mar 22
PubMed ID: 35318440
DOI: 10.1038/s41417-022-00451-8
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16726
Grinkevitch V, Wappett M, Crawford N, Price S, Lees A, McCann C, McAllister K, Prehn J, Young J, Bateson J, Gallagher L, Michaut M, Iyer V, Chatzipli A, Barthorpe S, Ciznadija D, Sloma I, Wesa A, Tice DA, Wessels L, Garnett M, Longley DB, McDermott U, McDade SS.
Functional Genomic Identification of Predictors of Sensitivity and Mechanisms of Resistance to Multivalent Second-Generation TRAIL-R2 Agonists
Mol Cancer Ther
2022
21(4):594-606
PubMed ID: 35086954
DOI: 10.1158/1535-7163.MCT-21-0532
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16854
Masaki Takahashi, Yoshifumi Hashimoto, Yoshikazu Nakamura
Anti-TGF-β1 aptamer enhances therapeutic effect of tyrosine kinase inhibitor, gefitinib, on non-small cell lung cancer in xenograft model
Molecular Therapy - Nucleic Acids
2022
29:969-978
PubMed ID: 36189081
DOI: 10.1016/j.omtn.2022.06.001
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20821
Li C, Zheng H, Xiong J, Huang Y, Li H, Jin H, Ai S, Wang Y, Su T, Sun G, Xiao X, Fu T, Wang Y, Gao X, Liang P.
miR-596-3p suppresses brain metastasis of non-small cell lung cancer by modulating YAP1 and IL-8.
Cell Death Dis
2022
13(8):699
PubMed ID: 35961957
DOI: 10.1038/s41419-022-05062-7
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20848
Satoh K, Sakai S, Nishizuka M.
Knockdown of RhoQ, a member of Rho GTPase, accelerates TGF-β-induced EMT in human lung adenocarcinoma.
Biochem Biophys Rep
2022
32:101346
PubMed ID: 36120491
DOI: 10.1016/j.bbrep.2022.101346
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20859
Onishi T, Takashima T, Kurashige M, Ohshima K, Morii E.
Mutually exclusive expression of EZH2 and H3K27me3 in non-small cell lung carcinoma.
Pathol Res Pract
2022
238:154071
PubMed ID: 35985089
DOI: 10.1016/j.prp.2022.154071
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20935
Deng H, Lei Q, Wang C, Wang Z, Chen H, Wang G, Yang N, Huang D, Yu Q, Yao M, Xiao X, Zhu G, Cheng C, Li Y, Li F, Tian P, Li W.
A fluorogenic probe for predicting treatment response in non-small cell lung cancer with EGFR-activating mutations.
Nat Commun
2022
13(1):6944
PubMed ID: 36376325
DOI: 10.1038/s41467-022-34627-5
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21853
Yuki Oka, Larina Tzu-Wei Shen, Tomoko Mori, Takumi Iwamura, Philippe Leproux, Satoshi Matsusaka, Hideaki Kano
Label-free visualization of cellular response to molecularly targeted agents using multiplex coherent anti-Stokes Raman scattering and third harmonic generation microscopy
Applied Physics Express
2022
15:102001
DOI: 10.35848/1882-0786/ac8d47
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20104
Abe K, Kanehira M, Ohkouchi S, Kumata S, Suzuki Y, Oishi H, Noda M, Sakurada A, Miyauchi E, Fujiwara T, Harigae H, Okada Y.
Targeting stanniocalcin-1-expressing tumor cells elicits efficient antitumor effects in a mouse model of human lung cancer.
Cancer Med
2021
PubMed ID: 33826244
DOI: 10.1002/cam4.3852
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14291
Isomura H, Taguchi A, Kajino T, Asai N, Nakatochi M, Kato S, Suzuki K, Yanagisawa K, Suzuki M, Fujishita T, Yamaguchi T, Takahashi M, Takahashi T.
Conditional Ror1 knockout reveals crucial involvement in lung adenocarcinoma development and identifies novel HIF-1α regulator
Cancer Sci
2021
112(4):1614-1623
PubMed ID: 33506575
DOI: 10.1111/cas.14825
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14368
Khaledian B, Taguchi A, Shin-Ya K, Kondo-Ida L, Kagaya N, Suzuki M, Kajino T, Yamaguchi T, Shimada Y, Takahashi T.
Inhibition of heat shock protein 90 destabilizes receptor tyrosine kinase ROR1 in lung adenocarcinoma
Cancer Sci
2021
112(3):1225-1234
PubMed ID: 33370472
DOI: 10.1111/cas.14786
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20304
Nakasone S, Suzuki A, Okazaki H, Onodera K, Zenkoh J, Ishii G, Suzuki Y, Tsuboi M, Tsuchihara K.
Predictive markers based on transcriptome modules for vinorelbine-based adjuvant chemotherapy for lung adenocarcinoma patients.
Lung Cancer
2021
158:115-125
PubMed ID: 34157583
DOI: 10.1016/j.lungcan.2021.06.011
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20365
He W, Qin M, Cai Y, Gao X, Cao S, Wang Z, Chen H, Xu R.
Downregulation of HOXC6 by miR-27a ameliorates gefitinib resistance in non-small cell lung cancer.
Am J Cancer Res
2021
11(9):4329-4346
PubMed ID: 34659890
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15836
Nanamiya R, Saito-Koyama R, Miki Y, Inoue C, Asavasupreechar T, Abe J, Sato I, Sasano H.
EphB4 as a Novel Target for the EGFR-Independent Suppressive Effects of Osimertinib on Cell Cycle Progression in Non-Small Cell Lung Cancer
Int J Mol Sci
2021
22(16):8522
PubMed ID: 34445227
DOI: 10.3390/ijms22168522
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15839
Poels KE, Schoenfeld AJ, Makhnin A, Tobi Y, Wang Y, Frisco-Cabanos H, Chakrabarti S, Shi M, Napoli C, McDonald TO, Tan W, Hata A, Weinrich SL, Yu HA, Michor F.
dentification of optimal dosing schedules of dacomitinib and osimertinib for a phase I/II trial in advanced EGFR-mutant non-small cell lung cancer
Nat Commun
2021
12(1):3697
PubMed ID: 34140482
DOI: 10.1038/s41467-021-23912-4
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15840
Fukuda K, Otani S, Takeuchi S, Arai S, Nanjo S, Tanimoto A, Nishiyama A, Naoki K, Yano S.
Trametinib overcomes KRAS-G12V-induced osimertinib resistance in a leptomeningeal carcinomatosis model of EGFR-mutant lung cancer
Cancer Sci
2021
112(9):3784-3795
PubMed ID: 34145930
DOI: 10.1111/cas.15035
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15846
Kawana S, Saito R, Miki Y, Kimura Y, Abe J, Sato I, Endo M, Sugawara S, Sasano H.
Suppression of tumor immune microenvironment via microRNA-1 after epidermal growth factor receptor-tyrosine kinase inhibitor resistance acquirement in lung adenocarcinoma
Cancer Med
2021
10(2):718-727
PubMed ID: 33305905
DOI: 10.1002/cam4.3639
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Xue L, Gao X, Zhang H, Tang J, Wang Q, Li F, Li X, Yu X, Lu Z, Huang Y, Tang R, Yang W.
Antiangiogenic antibody BD0801 combined with immune checkpoint inhibitors achieves synergistic antitumor activity and affects the tumor microenvironment
BMC Cancer
2021
21(1):1134
PubMed ID: 34686154
DOI: 10.1186/s12885-021-08859-5
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16219
Jeongmin Hong, Aya Shiba‐Ishii, Yunjung Kim, Masayuki Noguchi, Noriaki Sakamoto
Ovarian carcinoma immunoreactive antigen domain 2 controls mitochondrial apoptosis in lung adenocarcinoma
Cancer Sci
2021
112(12):5114-5126
PubMed ID: 34628698
DOI: 10.1111/cas.15160
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16281
Nachankar A, Oike T, Hanaoka H, Kanai A, Sato H, Yoshida Y, Obinata H, Sakai M, Osu N, Hirota Y, Takahashi A, Shibata A, Ohno T.
64 Cu-ATSM Predicts Efficacy of Carbon Ion Radiotherapy Associated with Cellular Antioxidant Capacity
Cancers (Basel)
2021
13(24):6159
PubMed ID: 34944777
DOI: 10.3390/cancers13246159
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20624
Nozaki M, Nishizuka M.
Repression of RhoJ expression promotes TGF-β-mediated EMT in human non-small-cell lung cancer A549cells.
Biochem Biophys Res Commun
2021
566:94-100
PubMed ID: 34119829
DOI: 10.1016/j.bbrc.2021.06.004
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16516
Tsuchiya K, Yoshimura K, Inoue Y, Iwashita Y, Yamada H, Kawase A, Watanabe T, Tanahashi M, Ogawa H, Funai K, Shinmura K, Suda T, Sugimura H.
YTHDF1 and YTHDF2 are associated with better patient survival and an inflamed tumor-immune microenvironment in non-small-cell lung cancer
Oncoimmunology
2021
10(1):1962656
PubMed ID: 34408926
DOI: 10.1080/2162402X.2021.1962656
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Liu J, Han X, Chen L, Han D, Mu X, Hu X, Wu H, Wu H, Liu W, Zhao Y.
TRIM28 is a distinct prognostic biomarker that worsens the tumor immune microenvironment in lung adenocarcinoma
Aging (Albany NY)
2020
12(20):20308-20331
PubMed ID: 33091876
DOI: 10.18632/aging.103804
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7054
Arai S, Takeuchi S, Fukuda K, Taniguchi H, Nishiyama A, Tanimoto A, Satouchi M, Yamashita K, Ohtsubo K, Nanjo S, Kumagai T, Katayama R, Nishio M, Zheng MM, Wu YL, Nishihara H, Yamamoto T, Nakada M, Yano S.
Osimertinib overcomes alectinib resistance caused by amphiregulin in a leptomeningeal carcinomatosis model of ALK-rearranged lung cancer.
J Thorac Oncol
2020
15(5):752-765
PubMed ID: 31972351
DOI: 10.1016/j.jtho.2020.01.001
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11955
Ren T, Fan XX, Wang MF, Duan FG, Wei CL, Li RZ, Jiang ZB, Wang YW, Yao XJ, Chen MW, Tang YJ, Leung EL.
miR‑20b promotes growth of non‑small cell lung cancer through a positive feedback loop of the Wnt/β‑catenin signaling pathway.
Int. J. Oncol.
2020
PubMed ID: 31894264
DOI: 10.3892/ijo.2019.4940
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12050
Azuma Y, Yokobori T, Mogi A, Yajima T, Kosaka T, Iijima M, Shimizu K, Shirabe K, Kuwano H.
Cancer exosomal microRNAs from gefitinib-resistant lung cancer cells cause therapeutic resistance in gefitinib-sensitive cells.
Surg. Today
2020
PubMed ID: 32052182
DOI: 10.1007/s00595-020-01976-x
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12085
Lin Y, Higashisaka K, Shintani T, Maki A, Hanamuro S, Haga Y, Maeda S, Tsujino H, Nagano K, Fujio Y, Tsutsumi Y.
Progesterone receptor membrane component 1 leads to erlotinib resistance, initiating crosstalk of Wnt/β-catenin and NF-κB pathways, in lung adenocarcinoma cells.
Sci Rep
2020
PubMed ID: 32179851
DOI: 10.1038/s41598-020-61727-3
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12089
Tanaka H, Hino H, Moriya S, Kazama H, Miyazaki M, Takano N, Hiramoto M, Tsukahara K, Miyazawa K.
Comparison of autophagy inducibility in various tyrosine kinase inhibitors and their enhanced cytotoxicity via inhibition of autophagy in cancer cells in combined treatment with azithromycin.
Biochem Biophys Rep
2020
PubMed ID: 32195376
DOI: 10.1016/j.bbrep.2020.100750
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13153
Suzuki S, Yamamoto M, Sanomachi T, Togashi K, Sugai A, Seino S, Okada M, Yoshioka T, Kitanaka C.
Doxazosin, a Classic Alpha 1-Adrenoceptor Antagonist, Overcomes Osimertinib Resistance in Cancer Cells via the Upregulation of Autophagy as Drug Repurposing.
Biomedicines
2020
PubMed ID: 32764319
DOI: 10.3390/biomedicines8080273
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13224
Wang R, Yamada T, Kita K, Taniguchi H, Arai S, Fukuda K, Terashima M, Ishimura A, Nishiyama A, Tanimoto A, Takeuchi S, Ohtsubo K, Yamashita K, Yamano T, Yoshimura A, Takayama K, Kaira K, Taniguchi Y, Atagi S, Uehara H, Hanayama R, Matsumoto I, Han X, Matsumoto K, Wang W, Suzuki T, Yano S.
Transient IGF-1R inhibition combined with osimertinib eradicates AXL-low expressing EGFR mutated lung cancer.
Nat Commun
2020
PubMed ID: 32929081
DOI: 10.1038/s41467-020-18442-4
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13283
Arai S, Takeuchi S, Fukuda K, Tanimoto A, Nishiyama A, Konishi H, Takagi A, Takahashi H, Ong ST, Yano S.
Resminostat, a histone deacetylase inhibitor, circumvents tolerance to EGFR inhibitors in EGFR-mutated lung cancer cells with BIM deletion polymorphism.
J Med Invest
2020
PubMed ID: 33148913
DOI: 10.2152/jmi.67.343
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13543
Okuno D, Sugiura Y, Sakamoto N, Tagod MSO, Iwasaki M, Noda S, Tamura A, Senju H, Umeyama Y, Yamaguchi H, Suematsu M, Morita CT, Tanaka Y, Mukae H.
Comparison of a Novel Bisphosphonate Prodrug and Zoledronic Acid in the Induction of Cytotoxicity in Human Vγ2Vδ2 T Cells
Front Immunol
2020
11:1405
PubMed ID: 32793196
DOI: 10.3389/fimmu.2020.01405
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13922
Kim H, Ishibashi K, Iijima M, Kuroda S, Nakamura C.
Influence of Nivolumab for Intercellular Adhesion Force between a T Cell and a Cancer Cell Evaluated by AFM Force Spectroscopy
Sensors (Basel)
2020
20(19):5723
PubMed ID: 33050090
DOI: 10.3390/s20195723
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14793
Okura N, Nishioka N, Yamada T, Taniguchi H, Tanimura K, Katayama Y, Yoshimura A, Watanabe S, Kikuchi T, Shiotsu S, Kitazaki T, Nishiyama A, Iwasaku M, Kaneko Y, Uchino J, Uehara H, Horinaka M, Sakai T, Tanaka K, Kozaki R, Yano S, Takayama K.
ONO-7475, a Novel AXL Inhibitor, Suppresses the Adaptive Resistance to Initial EGFR-TKI Treatment in EGFR-Mutated Non-Small Cell Lung Cancer
Clin Cancer Res
2020
26(9):2244-2256
PubMed ID: 31953310
DOI: 10.1158/1078-0432.CCR-19-2321
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14832
Saito S, Kitamura-Muramatsu Y, Komine F, Polat M, Takeshima SN, Takei M, Aida Y.
Absence of bovine leukemia virus proviral DNA in Japanese human blood cell lines and human cancer cell lines
Arch Virol
2020
165(1):207-214
PubMed ID: 31776677
DOI: 10.1007/s00705-019-04474-9
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14834
Saito R, Miki Y, Abe T, Miyauchi E, Abe J, Nanamiya R, Inoue C, Sato I, Sasano H.
11β hydroxysteroid dehydrogenase 1: a new marker for predicting response to immune-checkpoint blockade therapy in non-small-cell lung carcinoma
Br J Cancer
2020
123(1):61-71
PubMed ID: 32336752
DOI: 10.1038/s41416-020-0837-3
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17870
Yamaguchi T, Hayashi M, Ida L, Yamamoto M, Lu C, Kajino T, Cheng J, Nakatochi M, Isomura H, Yamazaki M, Suzuki M, Fujimoto T, Takahashi T.
ROR1-CAVIN3 interaction required for caveolae-dependent endocytosis and pro-survival signaling in lung adenocarcinoma
Oncogene
2019
38(26):5142-5157
PubMed ID: 30894682
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11336
Kosibaty Z, Murata Y, Minami Y, Dai T, Kano J, Matsuoka R, Nakano N, Noguchi M.
Cytoplasmic expression of epithelial cell transforming sequence 2 in lung adenocarcinoma and its implications for malignant progression.
Lab. Invest.
2019
PubMed ID: 30542068
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11372
Sun Y, Bandi M, Lofton T, Smith M, Bristow CA, Carugo A, Rogers N, Leonard P, Chang Q, Mullinax R, Han J, Shi X, Seth S, Meyers BA, Miller M, Miao L, Ma X, Feng N, Giuliani V, Geck Do M, Czako B, Palmer WS, Mseeh F, Asara JM, Jiang Y, Morlacchi P, Zhao S, Peoples M, Tieu TN, Warmoes MO, Lorenzi PL, Muller FL, DePinho RA, Draetta GF, Toniatti C, Jones P, Heffernan TP, Marszalek JR.
Functional Genomics Reveals Synthetic Lethality between Phosphogluconate Dehydrogenase and Oxidative Phosphorylation.
Cell Rep
2019
PubMed ID: 30625329
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Mol Cancer Res
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Spironolactone, a Classic Potassium-Sparing Diuretic, Reduces Survivin Expression and Chemosensitizes Cancer Cells to Non-DNA-Damaging Anticancer Drugs.
Cancers (Basel)
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Oncol Rep
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Int J Oncol
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Clin Cancer Res
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ChemMedChem
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Mol Cancer Res
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Oncogenesis
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Sci Rep
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Cell Stem Cell
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Mol Cancer Ther
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Discovery of N-((3R,4R)-4-Fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidine-3-yl)acrylamide (PF-06747775) through Structure-Based Drug Design: A High Affinity Irreversible Inhibitor Targeting Oncogenic EGFR Mutants with Selectivity over Wild-Type EGFR
J Med Chem
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miR-3941: A novel microRNA that controls IGBP1 expression and is associated with malignant progression of lung adenocarcinoma
Cancer Sci
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A novel, rapid point-of-care test for lung cancer patients to detect epidermal growth factor receptor gene mutations by using real-time droplet-PCR and fresh liquid cytology specimens
Oncol Rep
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Nature
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Nat Commun
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BMC Res Notes
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