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Cell No. : Cell Name
RCB3673 : Raji  update : 2024/01/17
CommentHuman cell line derived from Burkitt lymphoma. EBNA (EBV—nuclear antigen) positive. TKG0371 (Deposited from Tohoku Univ.).
Comment from the depositor
Terms and conditionsThere is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC.
Order Form Order Form(C-0005.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)  
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (
Basic information Depositor Fukuda, Hiroshi
Originator P. J. V. Pulvertaft
Year of deposit 2011
Original cell TKG0371
Animal _human < Mammals
Genus Homo
Species sapiens
Gender Male
Age at sampling 11 years
Tissue left maxilla
Disease name Burkitt's Lymphoma
Classification cancer
History Cell Resource Center for Biomedical Research, Tohoku University(TKG0371)
Lifespan infinite
Morphology lymphocyte-like
Cellosaurus(Expasy) CVCL_0511
deposit info
lot info
Medium Medium List
Culture type Suspension cells
Culture medium RPMI1640 + 10% FBS
Culture method
Antibiotics Free
Passage method dilution
Culture information Passage ratio 1 : 5 split
SC frequency Subculture : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
Animal PCR OK
Virus (HIV) Undetected
Virus (HTLV-1) (-)
Virus (EBV) (+)
STR(human) OK
deposit info
lot info
Reference information Reference 5
User's Publication 3

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1141  Ralph P, Moore, M A, Nilsson K  Lysozyme synthesis by established human and murine histiocytic lymphoma cell lines.  J Exp Med  1976  143:1528-33  PubMed ID: 1083890   DOI: 10.1084/jem.143.6.1528
4739  Huang CC, Minowada J.  Differential effects of infection with herpes simplex virus on the chromosomes of human hematopoietic cell lines.  Cancer Res  1972  32(6):1218-25  PubMed ID: 4337885  
2472      Trans N Y Acad Sci  1966  29:61   
479  Epstein, M A, Achong, B G, Barr, Y M, Zajac B, Henle G, Henle W  Morphological and virological investigations on cultured Burkitt tumor lymphoblasts (strain Raji).  J Natl Cancer Inst  1966  37:547-59  PubMed ID: 4288580  
972  Pulvertaft,R.J.V.  Cytology of Burkitt's tumor (African lymphoma).  Lancet  1964  1:238-240  PubMed ID: 14086209   DOI: 10.1016/s0140-6736(64)92345-1

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User's Publication
21441  Kanto N, Ohkawa Y, Kitano M, Maeda K, Shiida M, Ono T, Ota F, Kizuka Y, Kunimasa K, Nishino K, Mukai M, Seike M, Azuma A, Harada Y, Fukuda T, Gu J, Taniguchi N.  A highly specific antibody against the core fucose of the N-glycan in IgG identifies the pulmonary diseases and its regulation by CCL2.  J Biol Chem  2023    PubMed ID: 37865317   DOI: 10.1016/j.jbc.2023.105365
11509  Zhelev Z, Georgieva E, Lazarova D, Semkova S, Aoki I, Gulubova M, Higashi T, Bakalova R.  Redox Imaging to Distinguish Cells with Different Proliferative Indexes: Superoxide, Hydroperoxides, and Their Ratio as Potential Biomarkers.  Oxid Med Cell Longev  2019    PubMed ID: 31089411   DOI: 10.1155/2019/6373685
10518  Kiso K, Yoshifuji H, Oku T, Hikida M, Kitagori K, Hirayama Y, Nakajima T, Haga H, Tsuruyama T, Miyagawa-Hayashino A.  Transgelin-2 is upregulated on activated B-cells and expressed in hyperplastic follicles in lupus erythematosus patients.  PLoS ONE  2017  12:e0184738  PubMed ID: 28910360   DOI: 10.1371/journal.pone.0184738

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