細胞番号 : 細胞名
RCB3576 : Aska-SS
update : 2024/08/14
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| 細胞特性(Comment:英) | Human cell line derived from synovial sarcoma. |
| 細胞特性(日) | ヒト滑膜肉腫由来細胞株 |
| 細胞特性(寄託者記述:英) | |
| 細胞特性(寄託者記述:日) | |
| 使用条件(英) | In publishing research results obtained by the use of the BIOLOGICAL RESOURCE, a citation of the literature ref. (Stem Cells 2010;28:1119-1131) designated by the DEPOSITOR is required. |
| 使用条件(日) | 利用者は、研究成果の公表にあたって寄託者の指定する文献 (Stem Cells 2010;28:1119-1131) を引用すること。 |
| 備考(英) | |
| 備考(日) | |
| 提供申込書類(英) |
Order Form(C-0005.pdf)
MTA(C-0007.pdf)
MTA(C-0007p.pdf)
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Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
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| 提供申込書類(日) |
依頼書C-0001.pdf
同意書(非営利学術目的)C-0003.pdf
同意書(営利目的)C-0003p.pdf
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提供同意書は、使用機関の種類や目的に応じて、非営利学術目的 (C-XXXX) と営利目的 (C-XXXXp) の2種類があります。該当する提供同意書をご使用ください（詳細）。特許等の取得及び商業利用等は事前に必ず cellbank.brc@riken.jp までご連絡ください。
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| 提供手数料 |
手数料とお支払いについてはこちらをご覧ください。 |
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細胞基本情報
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寄託者 |
Naka, Norifumi
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| 樹立者 |
Naka, Norifumi
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| 寄託日 |
2011
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| 動物種 |
_human
< Mammals
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| 属名 |
Homo
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| 種名 |
sapiens
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| 性別 |
Male
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| 齢 |
27 years
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| 採取組織 |
subcutaneous tissue of groin
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| 病名 |
Synovial sarcoma (Stage 4)
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| 転移 |
Yes
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| 転移巣 |
Lung
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| 細胞分類 |
cancer
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| 初代培養日 |
2005
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|
細胞寿命 |
infinite
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| 細胞形態 |
other
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| Cellosaurus(Expasy) |
CVCL_6C43
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細胞培養・検査情報
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寄託時情報 |
ロット情報 |
| 培地・試薬情報 |
培地・試薬一覧はこちらをご覧ください。 |
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培養形態 |
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Adherent cells
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| 培地 |
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DMEM (high glucose, without Sodium pyruvate) + 20% FBS
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| 抗生物質 |
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Free
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継代方法 |
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0.25% Trypsin
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|
継代密度 |
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1 : 2-4 split
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| 継代・培地交換頻度 |
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Subculture : once/1-2 weeks, Medium Renewal : 2 times/week
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| 培養最適温度 |
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37
℃
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| 二酸化炭素濃度 |
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5
%
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| 凍結培地 |
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Medium + 10% DMSO
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| 凍結方法 |
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Slow freezing
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| マイコプラズマ/アコレプラズマ |
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(-)
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| 動物種PCR |
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OK
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| 個体識別検査 |
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OK
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| 画像情報 |
寄託時情報 | ロット情報 |
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| 文献情報 |
Reference(英) |
6件
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| Reference(日) |
0件
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| 利用者成果(英) |
7件
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| 利用者成果(日) |
0件
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| Reference(英) |
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22279
Sasagawa S, Kumai J, Wakamatsu T, Yui Y.
Improvement of histone deacetylase inhibitor efficacy by SN38 through TWIST1 suppression in synovial sarcoma
Cancer Innov
2024
3(2):e113
PubMed ID: 38946933
DOI: 10.1002/cai2.113
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15489
Yokoo S, Fujiwara T, Yoshida A, Uotani K, Morita T, Kiyono M, Hasei J, Nakata E, Kunisada T, Iwata S, Yonemoto T, Ueda K, Ozaki T.
Liquid Biopsy Targeting Monocarboxylate Transporter 1 on the Surface Membrane of Tumor-Derived Extracellular Vesicles from Synovial Sarcoma
Cancers (Basel)
2021
13(8):1823
PubMed ID: 33920416
DOI: 10.3390/cancers13081823
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15501
Yasui H, Imura Y, Outani H, Hamada K, Nakai T, Yamada S, Takenaka S, Sasagawa S, Araki N, Itoh K, Myoui A, Yoshikawa H, Naka N.
Trabectedin is a promising antitumour agent for synovial sarcoma
J Chemother
2016
28(5):417-24
PubMed ID: 27077926
DOI: 10.1080/1120009X.2015.1133013
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16270
Toru Wakamatsu, Norifumi Naka, Satoru Sasagawa, Takaaki Tanaka, Satoshi Takenaka, Nobuhito Araki, Takafumi Ueda, Yasuko Nishizawa, Hideki Yoshikawa, Kazuyuki Itoh
Deflection of vascular endothelial growth factor action by SS18-SSX and composite vascular endothelial growth factor- and chemokine (C-X-C motif) receptor 4-targeted therapy in synovial sarcoma
Cancer Sci
2014
105(9):1124-34
PubMed ID: 24975049
DOI: 10.1111/cas.12469
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15415
Yasui H, Naka N, Imura Y, Outani H, Kaneko K, Hamada K, Sasagawa S, Araki N, Ueda T, Itoh K, Myoui A, Yoshikawa H.
Tailored therapeutic strategies for synovial sarcoma: receptor tyrosine kinase pathway analyses predict sensitivity to the mTOR inhibitor RAD001
Cancer Lett
2014
347(1):114-22
PubMed ID: 24491407
DOI: 10.1016/j.canlet.2014.01.027
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3639
Naka N, Takenaka S, Araki N, Miwa T, Hashimoto N, Yoshioka K, Joyama S, Hamada K, Tsukamoto Y, Tomita Y, Ueda T, Yoshikawa H, Itoh K.
Synovial sarcoma is a stem cell malignancy.
Stem Cells.
2010
28(7):1119-31
PubMed ID: 20518020
DOI: 10.1002/stem.452
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| 利用者成果(英) |
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21776
Kinoshita H, Kinoshita S, Kamoda H, Hagiwara Y, Ohtori S, Yonemoto T.
The Combination of Auranofin and Celecoxib Suppresses Local Synovial Sarcoma Progression In Vivo.
Anticancer Res
2024
44(6):2453-2458
PubMed ID: 38821602
DOI: 10.21873/anticanres.17052
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22243
Sasaki M, Kato D, Yoshida H, Shimizu T, Ogiwara H.
Efficacy of CBP/p300 Dual Inhibitors against De-repression of KREMEN2 in cBAF-Deficient Cancers
Cancer Res Commun
2024
2024 Dec 3
PubMed ID: 39625239
DOI: 10.1016/s0305-4179(98)80001-6
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19686
Takeuchi M, Nishisho T, Toki S, Kawaguchi S, Tamaki S, Oya T, Uto Y, Katagiri T, Sairyo K.
Blue light induces apoptosis and autophagy by promoting ROS-mediated mitochondr
Cancer Med
2023
12(8):9668-9683
PubMed ID: 36722116
DOI: 10.1002/cam4.5664
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20225
Jayabal P, Zhou F, Lei X, Ma X, Blackman B, Weintraub ST, Houghton PJ, Shiio Y.
NELL2-cdc42 signaling regulates BAF complexes and Ewing sarcoma cell growth.
Cell Rep
2021
36(1):109254
PubMed ID: 34233189
DOI: 10.1016/j.celrep.2021.109254
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20274
Su BC, Hung GY, Tu YC, Yeh WC, Lin MC, Chen JY.
Marine Antimicrobial Peptide TP4 Exerts Anticancer Effects on Human Synovial Sarcoma Cells via Calcium Overload, Reactive Oxygen Species Production and Mitochondrial Hyperpolarization.
Mar Drugs
2021
19(2)
PubMed ID: 33562681
DOI: 10.3390/md19020093
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16177
Fairchild CK Jr, Floros KV, Jacob S, Coon CM, Puchalapalli M, Hu B, Harada H, Dozmorov MG, Koblinski JE, Smith SC, Domson G, Leverson JD, Souers AJ, Takebe N, Ebi H, Faber AC, Boikos SA.
Unmasking BCL-2 Addiction in Synovial Sarcoma by Overcoming Low NOXA
Cancers (Basel)
2021
13(10):2310
PubMed ID: 34065859
DOI: 10.3390/cancers13102310
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14603
Michel BC, D'Avino AR, Cassel SH, Mashtalir N, McKenzie ZM, McBride MJ, Valencia AM, Zhou Q, Bocker M, Soares LMM, Pan J, Remillard DI, Lareau CA, Zullow HJ, Fortoul N, Gray NS, Bradner JE, Chan HM, Kadoch C.
A non-canonical SWI/SNF complex is a synthetic lethal target in cancers driven by BAF complex perturbation
Nat Cell Biol
2018
20(12):1410-1420
PubMed ID: 30397315
DOI: 10.1038/s41556-018-0221-1
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