Cell No. : Cell Name
RCB3052 : Jurkat
update : 2020/09/24
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| Comment | Human T cell leukemia. IL-2 receptor (-). Progeny were cured by Treatments with BM Cycline and MC210. TKG0209 (Deposited from Tohoku Univ.). |
| Comment from the depositor | |
| Terms and conditions | There is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, a prior written permission of the DEPOSITOR or the RIKEN BRC is necessary. |
| Remarks | |
| Order Form |
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, Category I and II, depending on the sort of user institutions and the purposes of use.Please use an appropriate MTA(to see).In case of Restriction "a" or "f", please contact RIKEN BRC(cellbank.brc@riken.jp) regarding any kind of for-profit use.
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Basic information
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Depositor |
Fukuda, Hiroshi
|
| Year of deposit |
2010
|
| Original cell |
TKG0209
|
| Animal |
human
< Mammals
|
| Genus |
Homo
|
| Species |
sapiens
|
| Gender |
Male
|
| Age at sampling |
14 years
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| Tissue |
blood
|
| Case history |
acute T cell leukemia
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| Classification |
cancer
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| History |
Cell Resource Center for Biomedical Research, Tohoku University（TKG0209）
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|
Lifespan |
infinite
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| Morphology |
lymphocyte-like
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deposit info |
lot info |
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Medium |
Medium List |
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Culture type |
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Suspension cells
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| Medium and additives |
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RPMI1640 + 10% FBS
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| Antibiotics |
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Free
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Passage method |
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dilution
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Culture information
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Passage ratio |
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1 : 8 split
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| SC frequency |
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Subculture : 2 times/week
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| Temperature |
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37
℃
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| CO2 concentration |
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5
%
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| Freeze medium |
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Medium + 10% DMSO
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| Freezing method |
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Slow freezing
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| Mycoplasma |
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(-)
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| STR(human) |
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OK
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| Isozyme |
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LD, NP
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| Images |
deposit info | lot info |
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| Relational File |
deposit info | lot info |
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| Reference information |
Reference |
7
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| User's Publication |
7
|
| Reference |
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1640
LaGree KA, Lee AT, Stetten G, Strauss PR.
The human Jurkat (FHCRC-11) cell line is heterogeneous in ploidy and cell size and releases detergent-soluble DNA.
Exp Hematol
1988
16(8):686-90
PubMed ID: 3165345
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4749
Wendler I1, Jentsch KD, Schneider J, Hunsmann G.
Efficient replication of HTLV-III and STLV-IIImac in human Jurkat cells.
Med Microbiol Immunol
1987
176(5):273-80
PubMed ID: 2443825
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1685
Weiss A, Wiskocil RL, Stobo JD.
The role of T3 surface molecules in the activation of human T cells: a two-stimulus requirement for IL 2 production reflects events occurring at a pre-translational level.
J Immunol
1984
133(1):123-8
PubMed ID: 6327821
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1638
Pawelec G, Borowitz A, Krammer PH, Wernet P.
Constitutive interleukin 2 production by the JURKAT human leukemic T cell line.
Eur J Immunol
1982
12(5):387-92
PubMed ID: 6980126
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1637
Kahle P, Wernet P, Rehbein A, Kumbier I, Pawelec G.
Cloning of functional human T lymphocytes by limiting dilution: impact of filler cells and interleukin 2 sources on cloning efficiencies.
Scand J Immunol
1981
14(5):493-502
PubMed ID: 6278580
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515
Gillis S, Watson J.
Biochemical and biological characterization of lymphocyte regulatory molecules. V. Identification of an interleukin 2-producing human leukemia T cell line.
J Exp Med
1980
152(6):1709-19
PubMed ID: 6778951
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902
Schneider U, Schwenk HU, Bornkamm G.
Characterization of EBV-genome negative "null" and "T" cell lines derived from children with acute lymphoblastic leukemia and leukemic transformed non-Hodgkin lymphoma.
Int J Cancer
1977
19(5):621-6
PubMed ID: 68013
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| User's Publication |
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6947
Araki R1, Hoki Y, Suga T, Obara C, Sunayama M, Imadome K, Fujita M, Kamimura S, Nakamura M, Wakayama S, Nagy A, Wakayama T, Abe M.
Genetic aberrations in iPSCs are introduced by a transient G1/S cell cycle checkpoint deficiency.
Nat Commun
2020
11(1):197
PubMed ID: 31924765
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11347
Nomura H, Umekita K, Hashikura Y, Umeki K, Yamamoto I, Aratake Y, Saito M, Hasegawa H, Yanagihara K, Okayama A.
Diversity of cell phenotypes among MT-2 cell lines affects the growth of U937 cells and cytokine production.
Hum. Cell
2019
PubMed ID: 30560508
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11625
Kurosawa N, Wakata Y, Ida K, Midorikawa A, Isobe M.
High throughput development of TCR-mimic antibody that targets survivin-2B80-88/HLA-A*A24 and its application in a bispecific T-cell engager.
Sci Rep
2019
PubMed ID: 31285464
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10440
Shunko A Inada , Daniel ZKW
Evaluation of 389nm UV-LED to Induce Apoptosis in Leukemia Cells for Develop Implant Photonics-Device
Biomedical Journal of Scientific & Technical Research
2019
19:14688-14692B
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6902
Kozako T, Mellini P, Ohsugi T, Aikawa A, Uchida YI, Honda SI, Suzuki T.
Novel small molecule SIRT2 inhibitors induce cell death in leukemic cell lines.
BMC Cancer
2018
PubMed ID: 30081901
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10061
Hashikura Y, Umeki K, Umekita K, Nomura H, Yamada A, Yamamoto I, Hasegawa H, Yanagihara K, Okayama A.
Infection of defective human T-lymphotropic virus type 1.
Hum. Cell
2017
30:117-123
PubMed ID: 28070874
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9532
Horie Y, Nemoto H, Itoh M, Kosaka H, Morita K.
Fermented Brown Rice Extract Causes Apoptotic Death of Human Acute Lymphoblastic Leukemia Cells via Death Receptor Pathway.
Appl. Biochem. Biotechnol.
2016
178:1599-611
PubMed ID: 26769704
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Jurkat_CD3.pdf