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細胞番号 : 細胞名
RCB2979 : HCT116  update : 2024/03/15
細胞特性(Comment:英)Human cell line derived from colon cancer. Loss of the DNA mismatch repair gene (hMLH1).
細胞特性(日)ヒト大腸癌由来細胞株。ミスマッチ修復遺伝子(hMLH1)欠損。
細胞特性(寄託者記述:英)
細胞特性(寄託者記述:日)
使用条件(英)There is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC.
使用条件(日)基礎的研究につきましては、使用制限はありません。商業利用や特許取得を目的とする場合は、事前に必ず理研細胞バンクに連絡をすること。
備考(英)
備考(日)
提供申込書類(英) Order Form(C-0005.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)  
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
提供申込書類(日) 依頼書C-0001.pdf   同意書(非営利学術目的)C-0003.pdf   同意書(営利目的)C-0003p.pdf  
提供同意書は、使用機関の種類や目的に応じて、非営利学術目的 (C-XXXX) と営利目的 (C-XXXXp) の2種類があります。該当する提供同意書をご使用ください(詳細)。特許等の取得及び商業利用等は事前に必ず cellbank.brc@riken.jp までご連絡ください。
提供手数料 手数料とお支払いについてはこちらをご覧ください。
細胞基本情報 寄託者 Shiomi, Tadahiro
寄託日 2009
動物種 _human < Mammals
属名 Homo
種名 sapiens
性別 Male
採取組織 colon
細胞分類 cancer
細胞寿命 infinite
細胞形態 epithelial-like
Cellosaurus(Expasy) CVCL_0291
細胞培養・検査情報
寄託時情報
ロット情報
培地・試薬情報 培地・試薬一覧はこちらをご覧ください。
培養形態 Adherent cells
培地 DMEM (low glucose) + 10% FBS
抗生物質 Free
継代方法 0.25% Trypsin
継代密度 1 : 8 split
継代・培地交換頻度 Subculture : 2 times/week
培養最適温度 37 ℃
二酸化炭素濃度 5 %
凍結培地 Medium + 10% DMSO
凍結方法 Slow freezing
マイコプラズマ (-)
動物種PCR OK
個体識別検査 OK
画像情報
寄託時情報
ロット情報
文献情報 Reference(英) 3件
Reference(日) 0件
利用者成果(英) 127件
利用者成果(日) 0件

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Reference(英)
18268  Katsube T, Mori M, Tsuji H, Shiomi T, Shiomi N, Onoda M.  Differences in sensitivity to DNA-damaging Agents between XRCC4- and Artemis-deficient human cells  J Radiat Res  2011  52(4):415-24  PubMed ID: 21785230   DOI: 10.1269/jrr.10168
5492  Long BH, Willson JK, Brattain DE, Musial S, Brattain MG.  Effects of mitomycin on human colon carcinoma cells.  J Natl Cancer Inst  1984  73(4):787-92  PubMed ID: 6434780  
5491  Brattain MG, Fine WD, Khaled FM, Thompson J, Brattain DE.  Heterogeneity of malignant cells from a human colonic carcinoma.  Cancer Res  1981  41(5):1751-6  PubMed ID: 7214343  

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Reference(日)

トップへページトップへ
利用者成果(英)
17806  Shoji A, Arai Y, Asakawa R, Saito T, Kuramochi K, Yajima A.  Synthesis and structure-activity relationship of violaceoid D, a cytotoxic alkylated phenol isolated from Aspergillus violaceofuscus Gasperini  Biosci Biotechnol Biochem  2023  87(4):363-370  PubMed ID: 36592963   DOI: 10.1093/bbb/zbac212
19826  Nashimoto Y, Shishido S, Onuma K, Ino K, Inoue M, Shiku H.  Oxygen metabolism analysis of a single organoid for non-invasive discrimination of cancer subpopulations with different growth capabilities  Front Bioeng Biotechnol  2023  11:1184325  PubMed ID: 37274161   DOI: 10.3389/fbioe.2023.1184325
19960  Nakano M, Sakamoto T, Kitano Y, Bono H, Simpson RJ, Tabunoki H.  An extract from the frass of swallowtail butterfly (Papilio machaon) larvae inhibits HCT116 colon cancer cell proliferation but not other cancer cell types  BMC Genomics  2023  24(1):735  PubMed ID: 38049715   DOI: 10.1186/s12864-023-09841-0
19975  Aiba T, Hijiya N, Akagi T, Tsukamoto Y, Hirashita Y, Kinoshita K, Uchida T, Nakada C, Kurogi S, Ueda Y, Shiroshita H, Shiraishi N, Murakami K, Inomata M, Moriyama M.  Overexpression of VSNL1 enhances cell proliferation in colorectal carcinogenesis  Pathobiology  2023  Oct 5  PubMed ID: 37797604   DOI: 10.1159/000533877
21078  Tsuji D, Nakayama A, Yamamoto R, Nagano S, Taniguchi T, Sato R, Karanjit S, Muguruma N, Takayama T, Itoh K, Namba K.  1,3a,6a-Triazapentalene derivatives as photo-induced cytotoxic small fluorescent dyes.  Commun Chem  2023  6(1):37  PubMed ID: 36813913   DOI: 10.1038/s42004-023-00838-0
21273  Tomihari A, Kiyota M, Matsuura A, Itakura E.  Alpha 2-macroglobulin acts as a clearance factor in the lysosomal degradation of extracellular misfolded proteins.  Sci Rep  2023  13(1):4680  PubMed ID: 36977730   DOI: 10.1038/s41598-023-31104-x
21285  Morishita K, Kondo J, Sakon D, Hayashibara A, Tamura I, Shimizu K, Takamatsu S, Murata K, Kamada Y, Miyoshi E.  Prohaptoglobin is a possible prognostic biomarker for colorectal cancer.  Biochem Biophys Res Commun  2023  672:72-80  PubMed ID: 37343317   DOI: 10.1016/j.bbrc.2023.06.017
21307  Sumiyoshi S, Shiozaki A, Kosuga T, Simizu H, Kudo M, Kiuchi J, Arita T, Konishi H, Komatsu S, Kuriu Y, Kubota T, Fujiwara H, Morinaga Y, Konishi E, Otsuji E.  Functional Analysis and Clinical Importance of ATP1A1 in Colon Cancer.  Ann Surg Oncol  2023    PubMed ID: 37407874   DOI: 10.1245/s10434-023-13779-8
21320  Takeuchi H, Koga M, Doi K, Sakurai H.  PP2A and its adapter protein IER5 induce the DNA-binding ability and target gene expression of E2F1 via dephosphorylation at serine 375.  Biochim Biophys Acta Gene Regul Mech  2023  1866(3):194960  PubMed ID: 37467925   DOI: 10.1016/j.bbagrm.2023.194960
21327  Simanurak O, Pekthong D, Somran J, Wangteeraprasert A, Srikummool M, Kaewpaeng N, Parhira S, Srisawang P.  Enhanced apoptosis of HCT116 colon cancer cells treated with extracts from Calotropis gigantea stem bark by starvation.  Heliyon  2023  9(7):e18013  PubMed ID: 37483695   DOI: 10.1016/j.heliyon.2023.e18013
21364  Yamanaka S, Furihata H, Yanagihara Y, Taya A, Nagasaka T, Usui M, Nagaoka K, Shoya Y, Nishino K, Yoshida S, Kosako H, Tanokura M, Miyakawa T, Imai Y, Shibata N, Sawasaki T.  Lenalidomide derivatives and proteolysis-targeting chimeras for controlling neosubstrate degradation.  Nat Commun  2023  14(1):4683  PubMed ID: 37596276   DOI: 10.1038/s41467-023-40385-9
21403  Yamamoto T, Uehara R.  Cell shape instability during cytokinesis in tetraploid HCT116 cells.  Biochem Biophys Res Commun  2023  678:39-44  PubMed ID: 37619310   DOI: 10.1016/j.bbrc.2023.08.038
21510  Iwaki M, Kanemoto Y, Sawada T, Nojiri K, Kurokawa T, Tsutsumi R, Nagasawa K, Kato S.  Differential gene regulation by a synthetic vitamin D receptor ligand and active vitamin D in human cells.  PLoS One  2023  18(12):e0295288  PubMed ID: 38091304   DOI: 10.1371/journal.pone.0295288
21526  Pan Y, Suzuki T, Sakai K, Hirano Y, Ikeda H, Hattori A, Dohmae N, Nishio K, Kakeya H.  Bisabosqual A: A novel asparagine synthetase inhibitor suppressing the proliferation and migration of human non-small cell lung cancer A549 cells.  Eur J Pharmacol  2023  960:176156  PubMed ID: 38059445   DOI: 10.1016/j.ejphar.2023.176156
17551  Isotope Calculation Gadgets: A Series of Software for Isotope-Tracing Experiments in Garuda Platform  Isotope Calculation Gadgets: A Series of Software for Isotope-Tracing Experiments in Garuda Platform  Metabolites  2022  12(7):646  PubMed ID: 35888770   DOI: 10.3390/metabo12070646
17610  Yasudome R, Seki N, Asai S, Goto Y, Kita Y, Hozaka Y, Wada M, Tanabe K, Idichi T, Mori S, Ohtsuka T.  Molecular Pathogenesis of Colorectal Cancer: Impact of Oncogenic Targets Regulated by Tumor Suppressive miR-139-3p  Int J Mol Sci  2022  23(19):11616  PubMed ID: 36232922   DOI: 10.3390/ijms231911616
17660  Taniguchi G, Kajino K, Momose S, Saeki H, Yue L, Ohtsuji N, Abe M, Shibuya T, Orimo A, Nagahara A, Watanabe S, Hino O  The Inhibitory Effects of Anti-ERC/Mesothelin Antibody 22A31 on Colorectal Adenocarcinoma Cells, within a Mouse Xenograft Model  Cancers (Basel)  2022  14(9):2198  PubMed ID: 35565327   DOI: 10.3390/cancers14092198
17793  Kosuke Kimura, Takeshi Yasunaga, Takumi Makikawa, Daisuke Takahashi, Kazunobu Toshima  Efficient Strategy for the Preparation of Chemical Probes of Biologically Active Glycosides Using a Boron-Mediated Aglycon Delivery (BMAD) Method  Bulletin of the Chemical Society of Japan  2022  95:1075-1082    DOI: 10.1246/bcsj.20220076
17798  Chen P, Yang W, Hong T, Miyazaki T, Dirisala A, Kataoka K, Cabral H.  Nanocarriers escaping from hyperacidified endo/lysosomes in cancer cells allow tumor-targeted intracellular delivery of antibodies to therapeutically inhibit c-MYC  Biomaterials  2022  288:121748  PubMed ID: 36038419   DOI: 10.1016/j.biomaterials.2022.121748
16354  Koike M, Yutoku Y, Koike A.  Feline XRCC4 undergoes rapid Ku-dependent recruitment to DNA damage sites  FEBS Open Bio  2022  Jan 9  PubMed ID: 35000298   DOI: 10.1002/2211-5463.13363
16356  Monzen S, Ueno T, Chiba M, Morino Y, Mariya Y, Wojcik A, Lundholm L.  Dose-dependent expression of extracellular microRNAs in HCT116 colorectal cancer cells exposed to high-dose-rate ionising radiation  Mol Clin Oncol  2022  16(1):19  PubMed ID: 34881039   DOI: 10.3892/mco.2021.2452
20605  Ciftci H, Sever B, Ocak F, Bayrak N, Yıldız M, Yıldırım H, DeMirci H, Tateishi H, Otsuka M, Fujita M, TuYuN AF.  In Vitro and In Silico Study of Analogs of Plant Product Plastoquinone to Be Effective in Colorectal Cancer Treatment.  Molecules  2022  27(3)  PubMed ID: 35163957   DOI: 10.3390/molecules27030693
20703  Ali TFS, Ciftci HI, Radwan MO, Roshdy E, Shawky AM, Abourehab MAS, Tateishi H, Otsuka M, Fujita M.  Discovery of Azaindolin-2-One as a Dual Inhibitor of GSK3β and Tau Aggregation with Potential Neuroprotective Activity.  Pharmaceuticals (Basel)  2022  15(4)  PubMed ID: 35455423   DOI: 10.3390/ph15040426
20726  Hino SI, Inenaga K, Miyazaki T, Tanaka-Mizota C.  Suppression of HCT116 Human Colon Cancer Cell Motility by Polymethoxyflavones is Associated with Inhibition of Wnt/β-Catenin Signaling.  Nutr Cancer  2022  1-8  PubMed ID: 35658755   DOI: 10.1080/01635581.2022.2084122
20733  Masumoto K, Aihara Y, Miyagawa Kuroishi M, Maeda N, Sakai Y, Oka Y, Takahashi Y, Oda K, Yanagida M.  Highly sensitive and non-disruptive detection of residual undifferentiated cells by measuring miRNAs in culture supernatant.  Sci Rep  2022  12(1):10351  PubMed ID: 35725891   DOI: 10.1038/s41598-022-14273-z
20744  Asakawa R, Fuchiyama K, Ishii Y, Hosaka K, Kobayashi A, Shimazaki K, Nagasawa J, Tsuchida S, Ushida K, Matsubayashi M, Furuyama Y, Ohgane K, Kuramochi K.  Synthesis and Cytotoxic Activities of 8- and 6-Demethyleucalyptins.  Biosci Biotechnol Biochem  2022    PubMed ID: 35776954   DOI: 10.1093/bbb/zbac105
16724  Kenji Sugawara, Daichi Kanki, Ryuichi Watanabe, Ryoji Matsushima, Yuji Ise, Hisayoshi Yokose, Yasuhiro Morii, Nobuhiro Yamawaki, Akihiro Ninomiya, Shigeru Okada, Shigeki Matsunaga  Aciculitin D, a cytotoxic heterodetic cyclic peptide from a Poecillastra sp. marine sponge  Tetrahedron  2022  119:132859    DOI: 10.1016/j.tet.2022.132859
16725  Hasegawa T, Ito M, Hasegawa S, Teranishi M, Takeda K, Negishi S, Nishiwaki H, Takeda JI, LeBaron TW, Ohno K.  Molecular Hydrogen Enhances Proliferation of Cancer Cells That Exhibit Potent Mitochondrial Unfolded Protein Response  Int J Mol Sci  2022  23(5):2888  PubMed ID: 35270030   DOI: 10.3390/ijms23052888
20774  Kubota Y, Fujioka Y, Patil A, Takagi Y, Matsubara D, Iijima M, Momose I, Naka R, Nakai K, Noda NN, Takekawa M.  Qualitative differences in disease-associated MEK mutants reveal molecular signatures and aberrant signaling-crosstalk in cancer.  Nat Commun  2022  13(1):4063  PubMed ID: 35831322   DOI: 10.1038/s41467-022-31690-w
20799  Fujimoto M, Takii R, Matsumoto M, Okada M, Nakayama KI, Nakato R, Fujiki K, Shirahige K, Nakai A.  HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.  Nat Commun  2022  13(1):4355  PubMed ID: 35906200   DOI: 10.1038/s41467-022-32034-4
20846  Takahashi M, Sukowati EW, Nomura S, Kato A, Mizuseki K, Watanabe Y, Mukai H.  Impact of tumoral structure and bacterial species on growth and biodistribution of live bacterial therapeutics in xenografted tumours.  J Drug Target  2022  1-12  PubMed ID: 36097977   DOI: 10.1080/1061186X.2022.2122477
20853  Uranbileg B, Kurano M, Kano K, Sakai E, Arita J, Hasegawa K, Nishikawa T, Ishihara S, Yamashita H, Seto Y, Ikeda H, Aoki J, Yatomi Y.  Sphingosine 1-phosphate lyase facilitates cancer progression through converting sphingolipids to glycerophospholipids.  Clin Transl Med  2022  12(9):e1056  PubMed ID: 36125914   DOI: 10.1002/ctm2.1056
20955  Morotomi-Yano K, Hiromoto Y, Higaki T, Yano KI.  Disease-associated H58Y mutation affects the nuclear dynamics of human DNA topoisomerase IIβ.  Sci Rep  2022  12(1):20627  PubMed ID: 36450898   DOI: 10.1038/s41598-022-24883-2
20968  Ciftci H, Sever B, Bayrak N, Yıldız M, Yıldırım H, Tateishi H, Otsuka M, Fujita M, TuYuN AF.  In Vitro Cytotoxicity Evaluation of Plastoquinone Analogues against Colorectal and Breast Cancers along with In Silico Insights.  Pharmaceuticals (Basel)  2022  15(10)  PubMed ID: 36297378   DOI: 10.3390/ph15101266
21129  Ciftci H, Sever B, Kaya N, Bayrak N, Yıldız M, Yıldırım H, Tateishi H, Otsuka M, Fujita M, TuYuN AF.  Studies on 1,4-Quinone Derivatives Exhibiting Anti-Leukemic Activity along with Anti-Colorectal and Anti-Breast Cancer Effects.  Molecules  2022  28(1)  PubMed ID: 36615273   DOI: 10.3390/molecules28010077
13604  Jiang W, Jia N, Guo C, Wen J, Wu L, Ogi T, Zhang H.  Predominant cellular mitochondrial dysfunction in the TOP3A gene-caused Bloom syndrome-like disorder  Biochim Biophys Acta Mol Basis Dis  2021  1867(6):166106  PubMed ID: 33631320   DOI: 10.1016/j.bbadis.2021.166106
20083  Hama K, Fujiwara Y, Hayama T, Ozawa T, Nozawa K, Matsuda K, Hashiguchi Y, Yokoyama K.  Very long-chain fatty acids are accumulated in triacylglycerol and nonesterified forms in colorectal cancer tissues.  Sci Rep  2021  11(1):6163  PubMed ID: 33731797   DOI: 10.1038/s41598-021-85603-w
15080  Hirashita Y, Tsukamoto Y, Kudo Y, Kakisako D, Kurogi S, Hijiya N, Nakada C, Uchida T, Hirashita T, Hiratsuka T, Akagi T, Ueda Y, Shiroshita H, Etoh T, Mizukami K, Honda K, Okimoto T, Kodama M, Inomata M, Moriyama M, Murakami K.  Early response in phosphorylation of ribosomal protein S6 is associated with sensitivity to trametinib in colorectal cancer cells  Lab Invest  2021  101(8):1036-1047  PubMed ID: 33911189   DOI: 10.1038/s41374-021-00590-w
20272  Ma Y, Yoshida T, Matoba K, Kida K, Shintani R, Piao Y, Jin J, Nishino T, Hanayama R.  Identification of small compounds regulating the secretion of extracellular vesicles via a TIM4-affinity ELISA.  Sci Rep  2021  11(1):13471  PubMed ID: 34188113   DOI: 10.1038/s41598-021-92860-2
20311  Ashizawa N, Shimizu H, Shoda K, Furuya S, Akaike H, Hosomura N, Kawaguchi Y, Amemiya H, Kawaida H, Sudo M, Inoue S, Kono H, Katsurahara K, Shiozaki A, Ichikawa D.  NADPH oxidase 5 has a crucial role in cellular motility of colon cancer cells.  Int J Oncol  2021  59(2)  PubMed ID: 34278462   DOI: 10.3892/ijo.2021.5243
20372  Tamura N, Sakai S, Martorell L, Colomé R, Mizuike A, Goto A, Ortigoza-Escobar JD, Hanada K.  Intellectual disability-associated mutations in the ceramide transport protein gene CERT1 lead to aberrant function and subcellular distribution.  J Biol Chem  2021  101338  PubMed ID: 34688657   DOI: 10.1016/j.jbc.2021.101338
15709  Heishima K, Sugito N, Soga T, Nishikawa M, Ito Y, Honda R, Kuranaga Y, Sakai H, Ito R, Nakagawa T, Ueda H, Akao Y.  Petasin potently inhibits mitochondrial complex I-based metabolism that supports tumor growth and metastasis  J Clin Invest   2021  131(17):e139933  PubMed ID: 34623325   DOI: 10.1172/JCI139933
15870  Sudo H, Kubo A.  The Aneugenicity of Ketone Bodies in Colon Epithelial Cells Is Mediated by Microtubule Hyperacetylation and Is Blocked by Resveratrol  Int J Mol Sci  2021  22(17):9397  PubMed ID: 34502304   DOI: 10.3390/ijms22179397
16051  Maruoka M, Zhang P, Mori H, Imanishi E, Packwood DM, Harada H, Kosako H, Suzuki J.  Caspase cleavage releases a nuclear protein fragment that stimulates phospholipid scrambling at the plasma membrane  Mol Cell  2021  81(7):1397-1410.e9  PubMed ID: 33725486   DOI: 10.1016/j.molcel.2021.02.025
16067  Lazarova D, Semkova S, Zlateva G, Tatsuya H, Aoki I, Bakalova R.  Quantum Sensors To Track Total Redox-Status and Oxidative Stress in Cells and Tissues Using Electron-Paramagnetic Resonance, Magnetic Resonance Imaging, and Optical Imaging  Anal Chem  2021  93(5):2828-2837  PubMed ID: 33508934   DOI: 10.1021/acs.analchem.0c04116
16123  Zhou Y, Li X, Morita Y, Hachimura S, Miyakawa T, Takahashi S, Tanokura M.  Identification of the Effects of Chondroitin Sulfate on Inhibiting CDKs in Colorectal Cancer Based on Bioinformatic Analysis and Experimental Validation  Front Oncol9  2021  11:70593  PubMed ID: 34595111   DOI: 10.3389/fonc.2021.705939
16282  Hozaka Y, Kita Y, Yasudome R, Tanaka T, Wada M, Idichi T, Tanabe K, Asai S, Moriya S, Toda H, Mori S, Kurahara H, Ohtsuka T, Seki N.  RNA-Sequencing Based microRNA Expression Signature of Colorectal Cancer: The Impact of Oncogenic Targets Regulated by miR-490-3p  Int J Mol Sci   2021  22(18):9876  PubMed ID: 34576039   DOI: 10.3390/ijms22189876
18207  Shigematsu N, Kawashiri T, Kobayashi D, Shimizu S, Mine K, Hiromoto S, Uchida M, Egashira N, Shimazoe T.  Neuroprotective effect of alogliptin on oxaliplatin-induced peripheral neuropathy in vivo and in vitro  Sci Rep  2020  10(1):6734  PubMed ID: 32317735   DOI: 10.1038/s41598-020-62738-w
6918  Nagasawa I, Muroi M, Kawatani M, Ohishi T, Ohba SI, Kawada M, Osada H.  Identification of a Small Compound Targeting PKM2-Regulated Signaling Using 2D Gel Electrophoresis-Based Proteome-wide CETSA.  Cell Chem Biol  2020  27(2):186-196  PubMed ID: 31813846   DOI: 10.1016/j.chembiol.2019.11.010
9166  Yuka Nakazawa, Yuichiro Hara, Yasuyoshi Oka, Okiru Komine, Diana van den Heuvel, Chaowan Guo, Yasukazu Daigaku, Mayu Isono, Yuxi He, Mayuko Shimada, Kana Kato, Nan Jia, Satoru Hashimoto, Yuko Kotani, Yuka Miyoshi, Miyako Tanaka, Akira Sobue, Norisato Mitsutake, Takayoshi Suganami, Akio Masuda, Kinji Ohno, Shinichiro Nakada, Tomoji Mashimo, Koji Yamanaka, Martijn S Luijsterburg, Tomoo Ogi   Ubiquitination of DNA Damage-Stalled RNAPII Promotes Transcription-Coupled Repair  Cell  2020  180 (6), 1228-1244  PubMed ID: 32142649   DOI: 10.1016/j.cell.2020.02.010
9913  Satoshi Inoue, Takumi Tsunoda, Miho Riku, Hideaki Ito, Akihito Inoko, Hideki Murakami, Masahide Ebi, Naotaka Ogasawara, Ira Pastan, Kunio Kasugai, Kenji Kasai, Hiroshi Ikeda, Shingo Inaguma  Diffuse Mesothelin Expression Leads to Worse Prognosis Through Enhanced Cellular Proliferation in Colorectal Cancer  Oncol Lett  2020  19(3):1741-1750  PubMed ID: 32194667   DOI: 10.3892/ol.2020.11290
11905  Igarashi H, Taniguchi H, Nosho K, Ishigami K, Koide H, Mitsuhashi K, Okita K, Takemasa I, Imai K, Nakase H.  PRDM14 promotes malignant phenotype and correlates with poor prognosis in colorectal cancer.  Clin Transl Oncol  2020  22(7):1126-1137  PubMed ID: 31741141   DOI: 10.1007/s12094-019-02239-z
11910  Ujiie D, Okayama H, Saito K, Ashizawa M, Thar Min AK, Endo E, Kase K, Yamada L, Kikuchi T, Hanayama H, Fujita S, Sakamoto W, Endo H, Saito M, Mimura K, Saze Z, Momma T, Ohki S, Kono K.  KRT17 as a prognostic biomarker for stage II colorectal cancer.  Carcinogenesis  2020  41(5):591-599.  PubMed ID: 31754689   DOI: 10.1093/carcin/bgz192
12035  Kitao A, Kawamoto S, Kurata K, Hayakawa I, Yamasaki T, Matsuoka H, Sumi Y, Kakeji Y, Kamesaki T, Minami H.  Band 3 ectopic expression in colorectal cancer induces an increase in erythrocyte membrane-bound IgG and may cause immune-related anemia.  Int. J. Hematol.  2020    PubMed ID: 31997080   DOI: 10.1007/s12185-020-02831-y
12130  Sanada S, Suzuki T, Nagata A, Hashidume T, Yoshikawa Y, Miyoshi N.  Intestinal microbial metabolite stercobilin involvement in the chronic inflammation of ob/ob mice.  Sci Rep  2020    PubMed ID: 32296105   DOI: 10.1038/s41598-020-63627-y
12136  Choodej, Khanitha Pudhom  Cycloartane triterpenoids from the leaves of Euphorbia neriifolia  Phytochemistry Letters  2020      DOI: 10.1016/j.phytol.2019.10.005
12150  Amira Mira, Mohamed A. Sabry, Kuniyoshi Shimizu & Fatma M. Abdel Bar  A new pimarane-type diterpene obtained by biotransformation inhibits human HCT-116 colorectal carcinoma through inhibition of LTA4H activity  Original Research  2020      DOI: 10.1007/s00044-020-02520-9
13059  Ratsada P, Hijiya N, Hidano S, Tsukamoto Y, Nakada C, Uchida T, Kobayashi T, Moriyama M.  DUSP4 is involved in the enhanced proliferation and survival of DUSP4-overexpressing cancer cells.  Biochem Biophys Res Commun  2020    PubMed ID: 32505357   DOI: 10.1016/j.bbrc.2020.05.140
13210  Wada Y, Morine Y, Imura S, Ikemoto T, Saito Y, Takasu C, Yamada S, Shimada M.  HIF-1α expression in liver metastasis but not primary colorectal cancer is associated with prognosis of patients with colorectal liver metastasis.  World J Surg Oncol  2020    PubMed ID: 32895059   DOI: 10.1186/s12957-020-02012-5
13220  Miyano K, Okamoto S, Yamauchi A, Kajikawa M, Kiyohara T, Taura M, Kawai C, Kuribayashi F.  Constitutive activity of NADPH oxidase 1 (Nox1) that promotes its own activity suppresses the colon epithelial cell migration.  Free Radic Res  2020    PubMed ID: 32924676   DOI: 10.1080/10715762.2020.1823383
13390  Murakami H, Tamura N, Enomoto Y, Shimasaki K, Kurosawa K, Hanada K.  Intellectual disability-associated gain-of-function mutations in CERT1 that encodes the ceramide transport protein CERT.  PLoS One  2020    PubMed ID: 33347465   DOI: 10.1371/journal.pone.0243980
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