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Cell No. : Cell Name
RCB2799 : YAC-1  update : 2024/01/17
CommentMouse cell line derived from lymphoma. A/Sn strain. TKG0387 (Deposited from Tohoku Univ.).
Comment from the depositor
Terms and conditionsThere is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC.
Order Form Order Form(C-0005.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)  
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (
Basic information Depositor Fukuda, Hiroshi
Year of deposit 2008
Original cell TKG0387
Animal _mouse < Mammals
Strain name A/Sn
Tissue lymphoma
Classification cancer
History Cell Resource Center for Biomedical Research, Tohoku University(TKG0387)
Lifespan infinite
Morphology lymphoblast-like
Cellosaurus(Expasy) CVCL_2244
deposit info
lot info
Medium Medium List
Culture type Suspension cells
Culture medium RPMI1640 + 10% FBS
Culture method
Antibiotics Free
Passage method dilution
Culture information Passage ratio 1 : 8 split
SC frequency Subculture : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
SSLP(mouse) OK
Isozyme LD, NP
Reference information Reference 4
User's Publication 1

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4942  Tsai L, Ohlén C, Ljunggren HG, Kärre K, Hansson M, Kiessling R.  Effect of IFN-gamma treatment and in vivo passage of murine tumor cell lines on their sensitivity to lymphokine-activated killer (LAK) cell lysis in vitro; association with H-2 expression on the target cells.  Int J Cancer  1989  44(4):669-74  PubMed ID: 2507452   DOI: 10.1002/ijc.2910440419
4941  Klein GO, Grönberg A, Kiessling R, Klein G.  Decreased sensitivity of immunoselected and NK-selected YAC lymphoma sublines to hybrid resistance in vivo.  Eur J Cancer Clin Oncol  1982  18(2):191-8  PubMed ID: 6807680   DOI: 10.1016/0277-5379(82)90063-3
982  Kiessling R, Klein E, Wigzell H.  "Natural" killer cells in the mouse. I. Cytotoxic cells with specificity for mouse Moloney leukemia cells. Specificity and distribution according to genotype.  Eur J Immunol  1975  5(2):112-7  PubMed ID: 1234049   DOI: 10.1002/eji.1830050208
4940  Lamon EW, Gatti RA, Kiessling R, Fenyö EM.  Comparison of the allospecific and viral-specific immune responses to irradiated versus formaldehyde-fixed allogeneic Moloney lymphoma cells in CBA mice.  Cancer Res  1975  35(4):962-9  PubMed ID: 1090367  

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User's Publication
14402  Juman S, Hashimoto M, Katakura M, Inoue T, Tanabe Y, Arita M, Miki T, Shido O.  Effects of long-term oral administration of arachidonic acid and docosahexaenoic acid on the immune functions of young rats  Nutrients  2013  5(6):1949-61  PubMed ID: 23760060   DOI: 10.3390/nu5061949

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