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Cell No. : Cell Name
RCB2729 : LY-PPB6  update : 2021/05/20
CommentRat cell line derived from malignant peripheral nerve sheath tumor.
Comment from the depositor
Terms and conditionsThere is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC.
Order Form Order Form(C-0005.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)  
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (
Basic information Depositor Yamate, Jyoji
Originator Yamate, Jyoji
Year of deposit 2008
Animal rat < Mammals
Strain name F344/DuCrj
Gender Female
Tissue cervix
Disease name peripheral nerve sheath tumor
Classification cancer
Lifespan infinite
Morphology fibroblast-like
Cellosaurus(Expasy) CVCL_1Q80
deposit info
lot info
Medium Medium List
Culture type Adherent cells
Medium and additives DMEM (low glucose) + 10% FBS
Antibiotics Free
Passage method 0.25% Trypsin
Culture information Passage ratio 1 : 4-6 split
SC frequency Subculture : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
Animal PCR OK
deposit info
lot info
Reference information Reference 1
User's Publication 4

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3419  J Yamate, M Sakamori, M Kuwamura, T Kotani  Neoplastic and non-neoplastic cell lines from a malignant peripheral nerve sheath tumour of the cervix of a rat  J Comp Pathol  2007  137(1):9-21  PubMed ID: 17537454   DOI: 10.1016/j.jcpa.2007.03.004

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User's Publication
20648  Naitoh K, Orihara Y, Sakagami H, Miura T, Satoh K, Amano S, Bandow K, Iijima Y, Kurosaki K, Uesawa Y, Hashimoto M, Wakabayashi H.  Tumor-Specificity, Neurotoxicity, and Possible Involvement of the Nuclear Receptor Response Pathway of 4,6,8-Trimethyl Azulene Amide Derivatives.  Int J Mol Sci  2022  23(5)  PubMed ID: 35269748   DOI: 10.3390/ijms23052601
20884  Shindo A, Kusano M, Sakagami H, Amano S, Inomata M, Abe M, Okazawa M, Ooka T.  Comparison of UVC Sensitivity and Dectin-2 Expression Between Malignant and Non-malignant Cells.  In Vivo  2022  36(5):2116-2125  PubMed ID: 36099100   DOI: 10.21873/invivo.12937
13178  Yu H, Toume K, Kurokawa Y, Andoh T, Komatsu K.  Iridoids isolated from Viticis Fructus inhibit paclitaxel-induced mechanical allodynia in mice.  J Nat Med  2021    PubMed ID: 32816150   DOI: 10.1007/s11418-020-01441-6
10233  Andoh T, Uta D, Kato M, Toume K, Komatsu K, Kuraishi Y.  Prophylactic Administration of Aucubin Inhibits Paclitaxel-Induced Mechanical Allodynia via the Inhibition of Endoplasmic Reticulum Stress in Peripheral Schwann Cells.  Biol. Pharm. Bull.  2017  40:473-478  PubMed ID: 28381802   DOI: 10.1248/bpb.b16-00899

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