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Cell No. : Cell Name
RCB2657 : Colon-26  update : 2024/05/14
CommentMouse cell line derived from colon cancer. BALB/c strain. TKG0518 (Deposited from Tohoku Univ.).
Comment from the depositor
Terms and conditionsThere is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC.
Order Form Order Form(C-0005.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)  
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (
Basic information Depositor Fukuda, Hiroshi
Year of deposit 2007
Original cell TKG0518
Animal _mouse < Mammals
Strain name BALB/c
Tissue rectum
Disease name Rectum carcinoma
Classification cancer
History Cell Resource Center for Biomedical Research, Tohoku University(TKG0518)
Memo_1 A culture submitted to the CRCBR, Tohoku University was found to be contaminated with mycoplasma. Mycoplasma was eliminated with BM Cycline and MC210 at the CRCBR.
Lifespan infinite
Morphology fibroblast-like
Cellosaurus(Expasy) CVCL_0240
deposit info
lot info
Medium Medium List
Culture type Adherent cells
Culture medium RPMI1640 + 10% FBS
Antibiotics Free
Passage method 0.25% Trypsin
Culture information Passage ratio 1 : 10-20 split
SC frequency Subculture : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
Animal PCR OK
SSLP(mouse) OK
deposit info
lot info
Reference information Reference 1
User's Publication 135

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5251  Corbett TH, Griswold DP Jr, Roberts BJ, Peckham JC, Schabel FM Jr.  Tumor induction relationships in development of transplantable cancers of the colon in mice for chemotherapy assays, with a note on carcinogen structure.  Cancer Res  1975  35(9):2434-9  PubMed ID: 1149045  

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User's Publication
17687  Nomura S, Sukowati EW, Shigeno Y, Takahashi M, Kato A, Benno Y, Yamashita F, Mukai H.  Blautia coccoides JCM1395T Achieved Intratumoral Growth with Minimal Inflammation: Evidence for Live Bacterial Therapeutic Potential by an Optimized Sample Preparation and Colony PCR Method  Pharmaceutics  2023  15(3):989  PubMed ID: 36986850   DOI: 10.3390/pharmaceutics15030989
19552  Junrong Yang  Dynamic Effects of Ketogenic Diet on Autophagy and Cell Cycle in a Mouse Model of CT26+ Colon Cancer  Pakistan Journal of Zoology  2023      DOI: 10.17582/journal.pjz/20230222080203
19577  Tamura A, Osawa M, Yui N.  Supermolecule-Drug Conjugates Based on Acid-Degradable Polyrotaxanes for pH-Dependent Intracellular Release of Doxorubicin  Molecules  2023  28(6):2517  PubMed ID: 36985487   DOI: 10.3390/molecules28062517
19961  Komatsu Y, Yoshitomi T, Doan VTH, Kurokawa H, Fujiwara S, Kawazoe N, Chen G, Matsui H.  Locally Administered Photodynamic Therapy for Cancer Using Nano-Adhesive Photosensitizer  Pharmaceutics  2023  15(8):2076  PubMed ID: 37631290   DOI: 10.3390/pharmaceutics15082076
21004  Takemoto K, Hao L, Narukawa T, Iji M, Koyama T, Watanabe H.  Inhibition of Colorectal Cancer Cell Proliferation by Treatment with Itadori Leaf Extract.  J Oleo Sci  2023    PubMed ID: 36631102   DOI: 10.5650/jos.ess22245
21066  Ferdaos N, Harada A, Masuda E, Kasai S, Horaguchi T, Yoshizawa K.  Caffeine-Supplemented Diet Prevents Fatigue-Like Behavior in Tumor-Bearing Mice.  Nutr Cancer  2023    PubMed ID: 36714982   DOI: 10.1080/01635581.2022.2163669
21152  Fukuta T, Ikeda-Imafuku M, Kodama S, Kuse J, Matsui K, Iwao Y.  One-Step Pharmaceutical Preparation of PEG-Modified Exosomes Encapsulating Anti-Cancer Drugs by a High-Pressure Homogenization Technique.  Pharmaceuticals (Basel)  2023  16(1)  PubMed ID: 36678605   DOI: 10.3390/ph16010108
21182  Tsubaki M, Takeda T, Matsuda T, Kishimoto K, Takefuji H, Taniwaki Y, Ueda M, Hoshida T, Tanabe K, Nishida S.  Statins enhances antitumor effect of oxaliplatin in KRAS-mutated colorectal cancer cells and inhibits oxaliplatin-induced neuropathy.  Cancer Cell Int  2023  23(1):73  PubMed ID: 37069612   DOI: 10.1186/s12935-023-02884-z
21250  Miyazaki M, Sawada A, Sawamura D, Yoshida S.  Decreased insulin-like growth factor-1 expression in response to mechanical loading is associated with skeletal muscle anabolic resistance in cancer cachexia.  Growth Horm IGF Res  2023  69-70:101536  PubMed ID: 37229943   DOI: 10.1016/j.ghir.2023.101536
21411  Asano H, Elhelaly AE, Hyodo F, Iwasaki R, Noda Y, Kato H, Ichihashi K, Tomita H, Murata M, Mori T, Matsuo M.  Deuterium Magnetic Resonance Imaging Using Deuterated Water-Induced 2H-Tissue Labeling Allows Monitoring Cancer Treatment at Clinical Field Strength.  Clin Cancer Res  2023    PubMed ID: 37732903   DOI: 10.1158/1078-0432.CCR-23-1635
21425  Kametaka S, Isobe M, Komata K, Morinaga M, Nagahata K, Lee-Hotta S, Uchiyama Y, Shibata M, Sugiura H.  Protective effects of hachimijiogan (HJG), a Japanese Kampo medicine, on cancer cachectic muscle wasting in mice.  Biomed Res  2023  44(5):199-207  PubMed ID: 37779032   DOI: 10.2220/biomedres.44.199
17519  Hama S, Nishi T, Isono E, Itakura S, Yoshikawa Y, Nishimoto A, Suzuki S, Kirimura N, Todo H, Kogure K.  Intraperitoneal administration of nanoparticles containing tocopheryl succinate prevents peritoneal dissemination  Cancer Sci  2022  113(5):1779-1788  PubMed ID: 35253340   DOI: 10.1111/cas.15321
17523  Sakamoto Y, Suehiro F, Akiba I, Nishimura T.  Supramolecular Shear-Thinning Glycopeptide Hydrogels for Injectable Enzyme Prodrug Therapy Applications  Langmuir  2022  38(18):5883-5890  PubMed ID: 35471982   DOI: 10.1021/acs.langmuir.2c00504
17665  Masayuki Munekane, Asami Kosugi, Mizuho Yamasaki, Yoko Watanabe, Kento Kannaka, Kohei Sano, Toshihide Yamasaki, Ken-ichi Ogawara, Takahiro Mukai  Biodistribution study of indium-111-labeled PEGylated niosomes as novel drug carriers for tumor-targeting  Journal of Drug Delivery Science and Technology  2022  75:103648    DOI: 10.1016/j.jddst.2022.103648
17674  Ando H, Ikeda A, Tagami M, Matsuo NCA, Shimizu T, Ishima Y, Eshima K, Ishida T.  Oral administration of sodium bicarbonate can enhance the therapeutic outcome of Doxil® via neutralizing the acidic tumor microenvironment  J Control Release  2022  350:414-420  PubMed ID: 35988781   DOI: 10.1016/j.jconrel.2022.08.031
19514  Huu Hoang T, Sato-Matsubara M, Yuasa H, Matsubara T, Thuy LTT, Ikenaga H, Phuong DM, Hanh NV, Hieu VN, Hoang DV, Hai H, Okina Y, Enomoto M, Tamori A, Daikoku A, Urushima H, Ikeda K, Dat NQ, Yasui Y, Shinkawa H, Kubo S, Yamagishi R, Ohtani N, Yoshizato K, Gracia-Sancho J, Kawada N.  Cancer cells produce liver metastasis via gap formation in sinusoidal endothelial cells through proinflammatory paracrine mechanisms  Sci Adv  2022  8(39):eabo5525  PubMed ID: 36170363   DOI: 10.1126/sciadv.abo5525
19521  Okada H, Takahashi K, Yaku H, Kobiyama K, Iwaisako K, Zhao X, Shiokawa M, Uza N, Kodama Y, Ishii KJ, Seno H.  In situ vaccination using unique TLR9 ligand K3-SPG induces long-lasting systemic immune response and synergizes with systemic and local immunotherapy  Sci Rep  2022  12(1):2132  PubMed ID: 35136110   DOI: 10.1038/s41598-022-05702-0
19530  Hu D, Fumoto S, Miyamoto H, Tanaka M, Nishida K.  Flavonoids Enhance Lipofection Efficiency and Ameliorate Cytotoxicity in Colon26 and HepG2 Cells via Oxidative Stress Regulation  Pharmaceutics  2022  14(6):1203  PubMed ID: 35745776   DOI: 10.3390/pharmaceutics14061203
20380  Ma L, Sakamoto Y, Ando K, Fujita H, Takahashi A, Takeshima T, Otsuka H, Ebner DK, Kakimi K, Imai T, Shimokawa T.  Th balance related host genetic background affects the therapeutic effects of combining carbon-ion radiotherapy with dendritic cell immunotherapy.  Int J Radiat Oncol Biol Phys  2022    PubMed ID: 34740767   DOI: 10.1016/j.ijrobp.2021.10.141
20736  Šubr V, Pola R, Gao S, Islam R, Hirata T, Miyake D, Koshino K, Zhou JR, Yokomizo K, Fang J, Etrych T.  Tumor Stimulus-Responsive Biodegradable Diblock Copolymer Conjugates as Efficient Anti-Cancer Nanomedicines.  J Pers Med  2022  12(5)  PubMed ID: 35629120   DOI: 10.3390/jpm12050698
20741  Warashina S, Zouda M, Mohri K, Wada Y, Maeda K, Watanabe Y, Mukai H.  64Cu-labeling of small extracellular vesicle surfaces via a cross-bridged macrocyclic chelator for pharmacokinetic study by positron emission tomography imaging.  Int J Pharm  2022  121968  PubMed ID: 35772573   DOI: 10.1016/j.ijpharm.2022.121968
20791  Uemura M, Hiramoto K, Yoneyama H, Harusawa S, Komeda S.  Introduction of Fluorine into Antitumor-Active Dinuclear Platinum(II) Complexes Leads to Modulation of In Vivo Antitumor Activity in Mice.  Inorg Chem  2022    PubMed ID: 35876345   DOI: 10.1021/acs.inorgchem.2c01126
17104  El Sayed MM, Shimizu T, Abu Lila AS, Elsadek NE, Emam SE, Alaaeldin E, Kamal A, Sarhan HA, Ando H, Ishima Y, Ishida T.  A mouse model for studying the effect of blood anti-PEG IgMs levels on the in vivo fate of PEGylated liposomes  Int J Pharm  2022  615:121539  PubMed ID: 35124114   DOI: 10.1016/j.ijpharm.2022.121539
19517  Nomura TK, Heishima K, Sugito N, Sugawara R, Ueda H, Yukihiro A, Honda R.  Specific inhibition of oncogenic RAS using cell-permeable RAS-binding domains  Cell Chem Biol  2021  28(11):1581-1589.e6  PubMed ID: 33964212   DOI: 10.1016/j.chembiol.2021.04.013
19519  Chen CY, Ueha S, Ishiwata Y, Shichino S, Yokochi S, Yang D, Oppenheim JJ, Ogiwara H, Deshimaru S, Kanno Y, Aoki H, Ogawa T, Shibayama S, Matsushima K.  Combining an Alarmin HMGN1 Peptide with PD-L1 Blockade Results in Robust Antitumor Effects with a Concomitant Increase of Stem-Like/Progenitor Exhausted CD8+ T Cells  Cancer Immunol Res  2021  9(10):1214-1228  PubMed ID: 34344641   DOI: 10.1158/2326-6066.CIR-21-0265
20139  mam SE, Elsadek NE, Abu Lila AS, Takata H, Kawaguchi Y, Shimizu T, Ando H, Ishima Y, Ishida T.  Anti-PEG IgM production and accelerated blood clearance phenomenon after the administration of PEGylated exosomes in mice.  J Control Release  2021  334:327-334  PubMed ID: 33957196   DOI: 10.1016/j.jconrel.2021.05.001
14342  Ando H, Emam SE, Kawaguchi Y, Shimizu T, Ishima Y, Eshima K, Ishida T.  Increasing Tumor Extracellular pH by an Oral Alkalinizing Agent Improves Antitumor Responses of Anti-PD-1 Antibody: Implication of Relationships between Serum Bicarbonate Concentrations, Urinary pH, and Therapeutic Outcomes  Biol Pharm Bull  2021  44(6):844-852  PubMed ID: 34078817   DOI: 10.1248/bpb.b21-00076
15150  Morinaga M, Sako N, Isobe M, Lee-Hotta S, Sugiura H, Kametaka S.  Aerobic Exercise Ameliorates Cancer Cachexia-Induced Muscle Wasting through Adiponectin Signaling  Int J Mol Sci  2021  22(6):3110  PubMed ID: 33803685   DOI: 10.3390/ijms22063110
20320  Kitaoka Y, Miyazaki M, Kikuchi S.  Voluntary exercise prevents abnormal muscle mitochondrial morphology in cancer cachexia mice.  Physiol Rep  2021  9(16):e15016  PubMed ID: 34427401   DOI: 10.14814/phy2.15016
16067  Lazarova D, Semkova S, Zlateva G, Tatsuya H, Aoki I, Bakalova R.  Quantum Sensors To Track Total Redox-Status and Oxidative Stress in Cells and Tissues Using Electron-Paramagnetic Resonance, Magnetic Resonance Imaging, and Optical Imaging  Anal Chem  2021  93(5):2828-2837  PubMed ID: 33508934   DOI: 10.1021/acs.analchem.0c04116
16096  Sato Y, Fu Y, Liu H, Lee MY, Shaw MH.  Tumor-immune profiling of CT-26 and Colon 26 syngeneic mouse models reveals mechanism of anti-PD-1 response  BMC Cancer  2021  21(1):122  PubMed ID: 34774008   DOI: 10.1186/s12885-021-08974-3
16121  Sano K, Ishida Y, Tanaka T, Mizukami T, Nagayama T, Haratake Y, Munekane M, Yamasaki T, Mukai T.  Enhanced Delivery of Thermoresponsive Polymer-Based Medicine into Tumors by Using Heat Produced from Gold Nanorods Irradiated with Near-Infrared Light  Cancers (Basel)  2021  13(19):5005  PubMed ID: 34638489   DOI: 10.3390/cancers13195005
17865  Akiko OHKI, Yuhki YOKOYAMA, Tomoyo YASUDA, Shihori KOUDA, Satoshi SHIBATA, Yuki SHIMOMURA, Xin WU, Yoshinosuke HAMADA, Seiji MORI, Tsutomu TAKEDA, Kenya MURASE, Susumu TANAKA, Hirofumi YAMAMOTO  Determining the Tumor Suppressive Effects of a New Drug Delivery System Loaded with Iron Oxide Nanoparticles  Nano Biomedicine  2020  12    DOI: 10.11344/nano.12.43
19511  Asato Tonegawa, Atsushi Tamura, Shunyao Zhang, Nobuhiko Yui  Hydrophobicity of acyl groups in α-cyclodextrin-threaded polyrotaxanes dominates the formation and stability of self-assembled nanoparticles  Polymer  2020  200:122537    DOI: 10.1016/j.polymer.2020.122537
11792  Mimura A, Inaoka Y, Asakawa S, Murase K.  A Novel Cellular Imaging Method Using Hemagglutinating Virus of Japan-Envelope (HVJ-E) Vector and Magnetic Particle Imaging.  J Nanosci Nanotechnol  2020    PubMed ID: 31492206   DOI: 10.1166/jnn.2020.17322
12327  Mahib MR, Hosojima S, Kushiyama H, Kinoshita T, Shiroishi T, Suda T, Tsuchiya K.  Caspase-7 mediates caspase-1-induced apoptosis independently of Bid  Microbiol Immunol  2020  64(2):143-152  PubMed ID: 31687791   DOI: 10.1111/1348-0421.12756
13004  Yamada T, Ashida Y, Tatebayashi D, Abe M, Himori K.  Cancer Cachexia Induces Preferential Skeletal Muscle Myosin Loss When Combined With Denervation.  Front Physiol  2020    PubMed ID: 32425814   DOI: 10.3389/fphys.2020.00445
13266  Nomura S, Takahashi M, Kato AH, Wada Y, Watanabe Y, Yamashita F, Mukai H.  Biosorption-based 64Cu-labeling of bacteria for pharmacokinetic positron-emission tomography.  Int J Pharm  2020    PubMed ID: 33027635   DOI: 10.1016/j.ijpharm.2020.119950
13300  Takayama T, Shimizu T, Lila ASA, Kanazawa Y, Ando H, Ishima Y, Ishida T.  Adjuvant Antitumor Immunity Contributes to the Overall Antitumor Effect of Pegylated Liposomal Doxorubicin (Doxil®) in C26 Tumor-Bearing Immunocompetent Mice.  Pharmaceutics  2020    PubMed ID: 33086690   DOI: 10.3390/pharmaceutics12100990
13584  Uda RM, Yoshida N, Iwasaki T, Hayashi K.  pH-triggered solubility and cytotoxicity changes of malachite green derivatives incorporated in liposomes for killing cancer cells  J Mater Chem B  2020  8(36):8242-8248  PubMed ID: 32794526   DOI: 10.1039/d0tb01346c
13603  Imanishi M, Yamakawa Y, Fukushima K, Ikuto R, Maegawa A, Izawa-Ishizawa Y, Horinouchi Y, Kondo M, Kishuku M, Goda M, Zamami Y, Takechi K, Chuma M, Ikeda Y, Tsuchiya K, Fujino H, Tsuneyama K, Ishizawa K.  Fibroblast-specific ERK5 deficiency changes tumor vasculature and exacerbates tumor progression in a mouse model  Naunyn Schmiedebergs Arch Pharmacol  2020  393(7):1239-1250.  PubMed ID: 32307577   DOI: 10.1007/s00210-020-01859-5
13631  Mei T, Shashni B, Maeda H, Nagasaki Y.  Fibrinolytic tissue plasminogen activator installed redox-active nanoparticles (t-PA@iRNP) for cancer therapy  Biomaterials  2020  259:120290  PubMed ID: 32829147   DOI: 10.1016/j.biomaterials.2020.120290
15161  Kudláčová J, Kotrchová L, Kostka L, Randárová E, Filipová M, Janoušková O, Fang J, Etrych T.  Structure-to-Efficacy Relationship of HPMA-Based Nanomedicines: The Tumor Spheroid Penetration Study  Pharmaceutics  2020  12(12):1242  PubMed ID: 33419291   DOI: 10.3390/pharmaceutics12121242
11341  Fukuda T, Nanjo Y, Fujimoto M, Yoshida K, Natsui Y, Ishibashi F, Okazaki F, To H, Iwao M.  Lamellarin-inspired potent topoisomerase I inhibitors with the unprecedented benzo[g][1]benzopyrano[4,3-b]indol-6(13H)-one scaffold.  Bioorg. Med. Chem.  2019    PubMed ID: 30553626   DOI: 10.1016/j.bmc.2018.11.037
4573  Hatai M, Horiyama S, Yoshikawa N, Kinoshita E, Kagota S, Shinozuka K, Nakamura K.  trans-2-Pentenal, an Active Compound in Cigarette Smoke, Identified via Its Ability to Form Adducts with Glutathione.  Chem Pharm Bull (Tokyo)  2019  67(9):1000-1005  PubMed ID: 31474722   DOI: 10.1248/cpb.c19-00345
11506  Hayashi K, Watanabe M, Iwasaki T, Shudou M, Uda RM.  Endosomal escape by photo-activated fusion of liposomes containing a malachite green derivative: a novel class of photoresponsive liposomes for drug delivery vehicles.  Photochem. Photobiol. Sci.  2019    PubMed ID: 30964475   DOI: 10.1039/c8pp00495a
11530  Uda RM, Nishimoto N, Matsui T, Takagi S.  Photoinduced binding of malachite green copolymer to parallel G-quadruplex DNA.  Soft Matter  2019    PubMed ID: 31073583   DOI: 10.1039/c9sm00411d
11539  Suzuka H, Mimura A, Inaoka Y, Murase K.  Magnetic Nanoparticles in Macrophages and Cancer Cells Exhibit Different Signal Behavior on Magnetic Particle Imaging.  J Nanosci Nanotechnol  2019    PubMed ID: 31039837   DOI: 10.1166/jnn.2019.16619
11546  Tsuchiya K, Nakajima S, Hosojima S, Thi Nguyen D, Hattori T, Manh Le T, Hori O, Mahib MR, Yamaguchi Y, Miura M, Kinoshita T, Kushiyama H, Sakurai M, Shiroishi T, Suda T.  Caspase-1 initiates apoptosis in the absence of gasdermin D.  Nat Commun  2019    PubMed ID: 31064994   DOI: 10.1038/s41467-019-09753-2
11847  Matsui S, Kataoka H, Tanaka JI, Kikuchi M, Fukamachi H, Morisaki H, Matsushima H, Mishima K, Hironaka S, Takaki T, Okahashi N, Maruoka Y, Kuwata H.  Dysregulation of intestinal microbiota elicited by food allergy induces IgA-mediated oral dysbiosis.  Infect. Immun.  2019    PubMed ID: 31611274   DOI: 10.1128/IAI.00741-19
11859  Emam SE, Selim Abu Lila A, Elsadek NE, Ando H, Shimizu T, Okuhira K, Ishima Y, Mahdy MA, Ghazy FS, Ishid T.  Cancer cell-type tropism is one of crucial determinants for the efficient systemic delivery of cancer cell-derived exosomes to tumor tissues.  Eur J Pharm Biopharm  2019    PubMed ID: 31629787   DOI: 10.1016/j.ejpb.2019.10.005
9811  Eiji Kasumi, Norifumi Sato  A Ketogenic Diet Improves the Prognosis in a Mouse Model of Peritoneal Dissemination Without Tumor Regression  J Clin Biochem Nutr   2019  64(3):201-208  PubMed ID: 31138953   DOI: 10.3164/jcbn.18-103
10421  Yoshimi Inaoka, Tamami Keii, Atsushi Mimura, Kenya Murase  A Novel Therapeutic Strategy Combining Use of Intracellular Magnetic Nanoparticles under an Alternating Magnetic Field and Bleomycin  Open Journal of Applied Sciences  2019  9, Article ID:91110,17    DOI: 10.4236/ojapps.2019.93008
10589  Seiji Komeda, Masako Uemura, Hiroki Yoneyama, Shinya Harusawa and Keiichi Hiramoto  In Vitro Cytotoxicity and In Vivo Antitumor Efficacy of Tetrazolato-Bridged Dinuclear Platinum(II) Complexes with a Bulky Substituent at Tetrazole C5  Inorganics  2019  7(1):5    DOI: 10.3390/inorganics7010005
12407  Peng JQ, Fumoto S, Suga T, Miyamoto H, Kuroda N, Kawakami S, Nishida K.  Targeted co-delivery of protein and drug to a tumor in vivo by sophisticated RGD-modified lipid-calcium carbonate nanoparticles  J Control Release  2019  302:42-53  PubMed ID: 30926479   DOI: 10.1016/j.jconrel.2019.03.021
12408  Cancer therapy with major histocompatibility complex-deficient and interferon β-producing myeloid cells derived from allogeneic embryonic stem cells  Cancer therapy with major histocompatibility complex-deficient and interferon β-producing myeloid cells derived from allogeneic embryonic stem cells  Cancer Sci  2019  110(10):3027-3037  PubMed ID: 31348591   DOI: 10.1111/cas.14144
12409  Yamamoto S, Yamashita T, Ito M, Caaveiro JMM, Egashira N, Tozaki-Saitoh H, Tsuda M.  New pharmacological effect of fulvestrant to prevent oxaliplatin-induced neurodegeneration and mechanical allodynia in rats  Int J Cancer   2019  145(8):2107-2113  PubMed ID: 30515800   DOI: 10.1002/ijc.32043
10546  Miyamoto H, Tsujimoto H, Horii T, Ozamoto Y, Ueda J, Takagi T, Saitoh N, Hagiwara A.  The influences of a novel anti-adhesion device, thermally cross-linked gelatin film on peritoneal dissemination of tumor cells: The in vitro and in vivo experiments using murine carcinomatous peritonitis models.  J. Biomed. Mater. Res. Part B Appl. Biomater.  2018  106(6):2122-2130  PubMed ID: 29024447   DOI: 10.1002/jbm.b.34017
10733  Kawami M, Yamada Y, Issarachot O, Junyaprasert VB, Yumoto R, Takano M.  P-gp modulating effect of Azadirachta indica extract in multidrug-resistant cancer cell lines.  Pharmazie  2018  73:104-109  PubMed ID: 29442013   DOI: 10.1691/ph.2018.7116
10746  Miura K, Haraguchi M, Ito H, Tai A.  Potential Antitumor Activity of 2-O-α-d-Glucopyranosyl-6-O-(2-Pentylheptanoyl)-l-Ascorbic Acid.  Int J Mol Sci  2018  19:  PubMed ID: 29439410   DOI: 10.3390/ijms19020535
10772  Morio H, Sun Y, Harada M, Ide H, Shimozato O, Zhou X, Higashi K, Yuki R, Yamaguchi N, Hofbauer JP, Guttmann-Gruber C, Anzai N, Akita H, Chiba K, Furihata T.  Cancer-Type OATP1B3 mRNA in Extracellular Vesicles as a Promising Candidate for a Serum-Based Colorectal Cancer Biomarker.  Biol. Pharm. Bull.  2018  41:445-449  PubMed ID: 29491222   DOI: 10.1248/bpb.b17-00743
10827  Hatai M, Yoshikawa N, Kinoshita E, Horiyama S, Kagota S, Shinozuka K, Nakamura K.  Invasion-inhibiting Effects of Gaseous Components in Cigarette Smoke on Mouse Rectal Carcinoma Colon-26 Cells.  In Vivo  2018  32:493-497  PubMed ID: 29695551   DOI: 10.21873/invivo.11266
10831  Emam SE, Ando H, Abu Lila AS, Shimizu T, Ukawa M, Okuhira K, Ishima Y, Mahdy MA, Ghazy FS, Ishida T.  A Novel Strategy to Increase the Yield of Exosomes (Extracellular Vesicles) for an Expansion of Basic Research.  Biol. Pharm. Bull.  2018  41:733-742  PubMed ID: 29709910   DOI: 10.1248/bpb.b17-00919
11060  Hayashi K, Mitsuyoshi Y, Kamei T, Shimanouchi T, Suga K, Okamoto Y, Nakamura H, Umakoshi H.  Design of Pyrene–Fatty Acid Conjugates for Real-Time Monitoring of Drug Delivery and Controllability of Drug Release  ACS Omega  2018  3:3572-3580  PubMed ID: 30023872   DOI: 10.1021/acsomega.7b02061
11199  Kuroda K, Yamashita M, Murahata Y, Azuma K, Osaki T, Tsuka T, Ito N, Imagawa T, Okamoto Y.  Use of ozonated water as a new therapeutic approach to solve current concerns around antitumor treatment.  Exp Ther Med  2018  16(3):1597-1602  PubMed ID: 30186377   DOI: 10.3892/etm.2018.6415
11187  Noji M, So M, Yamaguchi K, Hojo H, Onda M, Akazawa-Ogawa Y, Hagihara Y, Goto Y.  Heat-Induced Aggregation of Hen Ovalbumin Suggests a Key Factor Responsible for Serpin Polymerization.  Biochemistry  2018  57(37):5415-5426  PubMed ID: 30148614   DOI: 10.1021/acs.biochem.8b00619
11224  Emam SE, Ando H, Lila ASA, Shimizu T, Okuhira K, Ishima Y, Mahdy MA, Ghazy FS, Sagawa I, Ishida T.  Liposome co-incubation with cancer cells secreted exosomes (extracellular vesicles) with different proteins expressions and different uptake pathways.  Sci Rep  2018    PubMed ID: 30262875   DOI: 10.1038/s41598-018-32861-w
4079  Yuba E, Osaki T, Ono M, Park S, Harada A, Yamashita M, Azuma K, Tsuka T, Ito N, Imagawa T, Okamoto Y.  Bleomycin-Loaded pH-Sensitive Polymer–Lipid-Incorporated Liposomes for Cancer Chemotherapy  Polymers  2018  10, 74  PubMed ID: 30966109   DOI: 10.3390/polym10010074
4179  Tatebayashi D, Himori K, Yamada R, Ashida Y, Miyazaki M, Yamada T.  High-intensity eccentric training ameliorates muscle wasting in colon 26 tumor-bearing mice.  PLoS ONE  2018    PubMed ID: 29894511   DOI: 10.1371/journal.pone.0199050
14600  Sano K, Kanada Y, Takahashi K, Ding N, Kanazaki K, Mukai T, Ono M, Saji H.  Enhanced Delivery of Radiolabeled Polyoxazoline into Tumors via Self-Aggregation under Hyperthermic Conditions  Mol Pharm  2018  15(9):3997-4003  PubMed ID: 30036483   DOI: 10.1021/acs.molpharmaceut.8b00441
10278  Miura K, Tai A.  2-O-α-D-Glucopyranosyl-l-ascorbic acid as an antitumor agent for infusion therapy.  Biochem Biophys Rep  2017  10:232-236  PubMed ID: 28955751   DOI: 10.1016/j.bbrep.2017.04.014
10424  Maeda M, Muragaki Y, Okamoto J, Yoshizawa S, Abe N, Nakamoto H, Ishii H, Kawabata K, Umemura S, Nishiyama N, Kataoka K, Iseki H.  Sonodynamic Therapy Based on Combined Use of Low Dose Administration of Epirubicin-Incorporating Drug Delivery System and Focused Ultrasound.  Ultrasound Med Biol  2017  43:2295-2301  PubMed ID: 28705555   DOI: 10.1016/j.ultrasmedbio.2017.06.003
10545  Ikemura M, Hashida T.  Effect of Hyperglycemia on Antitumor Activity and Survival in Tumor-bearing Mice Receiving Oxaliplatin and Fluorouracil.  Anticancer Res.  2017  37:5463-5468  PubMed ID: 28982857   DOI: 10.21873/anticanres.11975
10991  AKIKO OHKI, MINORI TANOUE, SAYUMI KOBAYASHI, KENYA MURASE  Magnetic Particle Imaging for Quantitative Evaluation of Tumor Response to Magnetic Hyperthermia Treatment Combined with Chemotherapy Using Cisplatin  Thermal Medicine  2017  33, 39-51    DOI: 10.3191/thermalmed.33.39
11017    Comparative Study of Extracellular and Intracellular Magnetic Hyperthermia Treatments Using Magnetic Particle Imaging  Open Journal of Applied Sciences  2017  7, 647-660    DOI: 10.4236/ojapps.2017.712047
5395  Kokuryo D, Aoki I, Yuba E, Kono K, Aoshima S, Kershaw J, Saga T.  Evaluation of a combination tumor treatment using thermo-triggered liposomal drug delivery and carbon ion irradiation.  Transl Res  2017  185:24-33  PubMed ID: 28482173   DOI: 10.1016/j.trsl.2017.04.001
10855  Shimaoka H, Takeno S, Maki K, Sasaki T, Hasegawa S, Yamashita Y.  A cytokine signal inhibitor for rheumatoid arthritis enhances cancer metastasis via depletion of NK cells in an experimental lung metastasis mouse model of colon cancer  Oncol Lett  2017  14(3):3019-3027  PubMed ID: 28928840   DOI: 10.3892/ol.2017.6473
14669  Gao Z, Nakanishi Y, Noda S, Omachi H, Shinohara H, Kimura H, Nagasaki Y.  Development of Gd 3 N@C 80 encapsulated redox nanoparticles for high-performance magnetic resonance imaging  J Biomater Sci Polym Ed  2017  28(10-12):1036-1050  PubMed ID: 28132586   DOI: 10.1080/09205063.2017.1288774
14719  Sano K, Ohashi M, Kanazaki K, Makino A, Ding N, Deguchi J, Kanada Y, Ono M, Saji H.  Indocyanine Green-Labeled Polysarcosine for in Vivo Photoacoustic Tumor Imaging  Bioconjug Chem  2017  28(4):1024-1030  PubMed ID: 28166625   DOI: 10.1021/acs.bioconjchem.6b00715
14720  Ohyama A, Higashi T, Motoyama K, Arima H.  Ternary complexes of folate-PEG-appended dendrimer (G4)/α-cyclodextrin conjugate, siRNA and low-molecular-weight polysaccharide sacran as a novel tumor-selective siRNA delivery system  Int J Biol Macromol  2017  99:21-28  PubMed ID: 28223132   DOI: 10.1016/j.ijbiomac.2017.02.045
14721  Miki K, Enomoto A, Inoue T, Nabeshima T, Saino S, Shimizu S, Matsuoka H, Ohe K.  Polymeric Self-Assemblies with Boron-Containing Near-Infrared Dye Dimers for Photoacoustic Imaging Probes  Biomacromolecules  2017  18(1):249-256  PubMed ID: 27936606   DOI: 10.1021/acs.biomac.6b01568
14722  Kanemaru H, Yamane F, Fukushima K, Matsuki T, Kawasaki T, Ebina I, Kuniyoshi K, Tanaka H, Maruyama K, Maeda K, Satoh T, Akira S.  Antitumor effect of Batf2 through IL-12 p40 up-regulation in tumor-associated macrophages  Proc Natl Acad Sci U S A  2017  114(35):E7331-E7340  PubMed ID: 28808017   DOI: 10.1073/pnas.1708598114
14736  Takara K, Eino D, Ando K, Yasuda D, Naito H, Tsukada Y, Iba T, Wakabayashi T, Muramatsu F, Kidoya H, Fukuhara S, Mochizuki N, Ishii S, Kishima H, Takakura N.  Lysophosphatidic Acid Receptor 4 Activation Augments Drug Delivery in Tumors by Tightening Endothelial Cell-Cell Contact  Cell Rep  2017  20(9):2072-2086  PubMed ID: 28854359   DOI: 10.1016/j.celrep.2017.07.080
14748  Yamamoto S, Ushio S, Egashira N, Kawashiri T, Mitsuyasu S, Higuchi H, Ozawa N, Masuguchi K, Ono Y, Masuda S.  Excessive spinal glutamate transmission is involved in oxaliplatin-induced mechanical allodynia: a possibility for riluzole as a prophylactic drug  Sci Rep  2017  7(1):9661  PubMed ID: 28851920   DOI: 10.1038/s41598-017-08891-1
7141  Vong LB, Nagasaki Y.  Combination Treatment of Murine Colon Cancer with Doxorubicin and Redox Nanoparticles.  Mol. Pharm.  2016  13:449-55  PubMed ID: 26605906   DOI: 10.1021/acs.molpharmaceut.5b00676
7209  Osaki T, Yokoe I, Uto Y, Ishizuka M, Tanaka T, Yamanaka N, Kurahashi T, Azuma K, Murahata Y, Tsuka T, Ito N, Imagawa T, Okamoto Y.  Bleomycin enhances the efficacy of sonodynamic therapy using aluminum phthalocyanine disulfonate.  Ultrason Sonochem  2016  28:161-168  PubMed ID: 26384895   DOI: 10.1016/j.ultsonch.2015.07.013
9507  Ohyama A, Higashi T, Motoyama K, Arima H.  In Vitro and In Vivo Tumor-Targeting siRNA Delivery Using Folate-PEG-appended Dendrimer (G4)/α-Cyclodextrin Conjugates.  Bioconjug. Chem.  2016  27:521-32  PubMed ID: 26715308   DOI: 10.1021/acs.bioconjchem.5b00545
9753  Gao Z, Horiguchi Y, Nakai K, Matsumura A, Suzuki M, Ono K, Nagasaki Y.  Use of boron cluster-containing redox nanoparticles with ROS scavenging ability in boron neutron capture therapy to achieve high therapeutic efficiency and low adverse effects.  Biomaterials  2016  104:201-12  PubMed ID: 27467416   DOI: 10.1016/j.biomaterials.2016.06.046
9856  Kanazaki K, Sano K, Makino A, Homma T, Ono M, Saji H.  Polyoxazoline multivalently conjugated with indocyanine green for sensitive in vivo photoacoustic imaging of tumors.  Sci Rep  2016  6:33798  PubMed ID: 27667374   DOI: 10.1038/srep33798
9995  Yamano T, Kubo S, Fukumoto M, Yano A, Mawatari-Furukawa Y, Okamura H, Tomita N.  Whole cell vaccination using immunogenic cell death by an oncolytic adenovirus is effective against a colorectal cancer model.  Mol Ther Oncolytics  2016  3:16031  PubMed ID: 28035331   DOI: 10.1038/mto.2016.31
10859  Tomomi Kuboyabu, Isamu Yabata, Marina Aoki, Natsuo Banura, Kohei Nishimoto, Atsushi Mimura, Kenya Murase  Magnetic Particle Imaging for Magnetic Hyperthermia Treatment: Visualization and Quantification of the Intratumoral Distribution and Temporal Change of Magnetic Nanoparticles in Vivo  Open Journal of Medical Imaging  2016  6:1-15    DOI: 10.4236/ojmi.2016.61001
10896  Tomomi Kuboyabu, Mikiko Yamawaki, Marina Aoki, Akiko Ohki, Kenya Murase   Quantitative Evaluation of Tumor Early Response to Magnetic Hyperthermia combined with Vascular Disrupting Therapy using Magnetic Particle Imaging  International Journal of Nanomedicine and Nanosurgery  2016  2.3    DOI: 10.16966/2470-3206.114
12406  Akiko Ohki, Tomomi Kuboyabu, Marina Aoki, Mikiko Yamawaki, Kenya Murase  Quantitative Evaluation of Tumor Response to combination of Magnetic Hyperthermia Treatment and Radiation Therapy using Magnetic Particle Imaging  Int J Nanomed Nanosurg  2016  2.3    DOI: 10.16966/2470-3206.117
12691  Suzuki R, Oda Y, Omata D, Nishiie N, Koshima R, Shiono Y, Sawaguchi Y, Unga J, Naoi T, Negishi Y, Kawakami S, Hashida M, Maruyama K.  Tumor growth suppression by the combination of nanobubbles and ultrasound  Cancer Sci  2016  107(3):217-23  PubMed ID: 26707839   DOI: 10.1111/cas.12867
14132  Okazaki F, Matsunaga N, Okazaki H, Azuma H, Hamamura K, Tsuruta A, Tsurudome Y, Ogino T, Hara Y, Suzuki T, Hyodo K, Ishihara H, Kikuchi H, To H, Aramaki H, Koyanagi S, Ohdo S.  Circadian Clock in a Mouse Colon Tumor Regulates Intracellular Iron Levels to Promote Tumor Progression  J Biol Chem  2016  291(13):7017-28  PubMed ID: 26797126   DOI: 10.1074/jbc.M115.713412
17834  Kurokawa H, Ito H, Inoue M, Tabata K, Sato Y, Yamagata K, Kizaka-Kondoh S, Kadonosono T, Yano S, Inoue M, Kamachi T.  High resolution imaging of intracellular oxygen concentration by phosphorescence lifetime  Sci Rep   2015  5:10657  PubMed ID: 26065366   DOI: 10.1038/srep10657
7116  Hayashi K, Kiriishi M, Suga K, Okamoto Y, Umakoshi H.  Investigation of Fatty Acid Ketohydrazone Modified Liposome's Properties as a Drug Carrier.  J Drug Deliv  2015  2015:481670  PubMed ID: 26649201   DOI: 10.1155/2015/481670
7167  Kuroda K, Azuma K, Mori T, Kawamoto K, Murahata Y, Tsuka T, Osaki T, Ito N, Imagawa T, Itoh F, Okamoto Y.  The Safety and Anti-Tumor Effects of Ozonated Water in Vivo.  Int J Mol Sci  2015  16:25108-20  PubMed ID: 26506343   DOI: 10.3390/ijms161025108
7195  Narayanan NK, Kunimasa K, Yamori Y, Mori M, Mori H, Nakamura K, Miller G, Manne U, Tiwari AK, Narayanan B.  Antitumor activity of melinjo (Gnetum gnemon L.) seed extract in human and murine tumor models in vitro and in a colon-26 tumor-bearing mouse model in vivo.  Cancer Med  2015  4:1767-80  PubMed ID: 26408414   DOI: 10.1002/cam4.520
7261  Aikawa T, Ito S, Shinohara M, Kaneko M, Kondo T, Yuasa M.  A drug formulation using an alginate hydrogel matrix for efficient oral delivery of the manganese porphyrin-based superoxide dismutase mimic.  Biomater Sci  2015  3:861-9  PubMed ID: 26221846   DOI: 10.1039/c5bm00056d
7364  Arai Y, Yamamoto T, Minamikawa T, Takamatsu T, Nagai T.  Spectral fingerprinting of individual cells visualized by cavity-reflection-enhanced light-absorption microscopy.  PLoS ONE  2015  10:e0125733  PubMed ID: 25950513   DOI: 10.1371/journal.pone.0125733
7366  Vong LB, Yoshitomi T, Matsui H, Nagasaki Y.  Development of an oral nanotherapeutics using redox nanoparticles for treatment of colitis-associated colon cancer.  Biomaterials  2015  55:54-63  PubMed ID: 25934452   DOI: 10.1016/j.biomaterials.2015.03.037
7555  Ryota Araki, Shoji Nishida, Yosuke Hiraki, Takeshi Yabe  Kamikihito ameliorates tumor‐induced sickness behavior in mice.  Traditional & Kampo Medicine  2015  2:93-96    DOI: 10.1002/tkm2.1025
7571  Y. Miura, A. B. Tsuji, A. Sugyo, H. Sudo, I. Aoki, M. Inubushi, M. Yashiro, K. Hirakawa, H. Cabral, N. Nishiyama, T. Saga, K. Kataoka  Polymeric Micelle Platform for Multimodal Tomographic Imaging to Detect Scirrhous Gastric Cancer.  ACS Biomater Sci Eng  2015  1:1067?1076  PubMed ID: 33429548   DOI: 10.1021/acsbiomaterials.5b00142
12246  Kaori Miura, Futoshi Yazama, Akihiro Tai  Oxidative stress-mediated antitumor activity of erythorbic acid in high doses  Biochem Biophys Rep  2015  3:117-122  PubMed ID: 29124174   DOI: 10.1016/j.bbrep.2015.07.018
15071  Shinya T, Yokota T, Nakayama S, Oki S, Mutoh J, Takahashi S, Sato K.  Orally Administered Mucolytic Drug l-Carbocisteine Inhibits Angiogenesis and Tumor Growth in Mice  J Pharmacol Exp Ther  2015  354(3):269-78  PubMed ID: 26126534   DOI: 10.1124/jpet.115.224816
11037  Takemura R, Takaki H, Okada S, Shime H, Akazawa T, Oshiumi H, Matsumoto M, Teshima T, Seya T.  PolyI:C-Induced, TLR3/RIP3-Dependent Necroptosis Backs Up Immune Effector-Mediated Tumor Elimination In Vivo  Cancer Immunol Res  2015  3(8):902-14  PubMed ID: 25898986   DOI: 10.1158/2326-6066.CIR-14-0219
15236  Kudo S, Nagasaki Y.  A novel nitric oxide-based anticancer therapeutics by macrophage-targeted poly(l-arginine)-based nanoparticles  J Control Release  2015  217:256-62  PubMed ID: 26386436   DOI: 10.1016/j.jconrel.2015.09.019
15437  Miki K, Inoue T, Kobayashi Y, Nakano K, Matsuoka H, Yamauchi F, Yano T, Ohe K.  Near-infrared dye-conjugated amphiphilic hyaluronic acid derivatives as a dual contrast agent for in vivo optical and photoacoustic tumor imaging  Biomacromolecules  2015  16(1):219-27  PubMed ID: 25402751   DOI: 10.1021/bm501438e
15481  Fujita S, Ushio S, Ozawa N, Masuguchi K, Kawashiri T, Oishi R, Egashira N.  Exenatide Facilitates Recovery from Oxaliplatin-Induced Peripheral Neuropathy in Rats  PLoS One  2015  10(11):e0141921  PubMed ID: 26536615   DOI: 10.1371/journal.pone.0141921
19513  Kanazaki K, Sano K, Makino A, Takahashi A, Deguchi J, Ohashi M, Temma T, Ono M, Saji H.  Development of human serum albumin conjugated with near-infrared dye for photoacoustic tumor imaging  J Biomed Opt  2014  19(9):96002.  PubMed ID: 25191833   DOI: 10.1117/1.JBO.19.9.096002
19515  Abdelwahab AF, Ohyama A, Higashi T, Motoyama K, Khaled KA, Sarhan HA, Hussein AK, Arima H.  Preparation and evaluation of polyamidoamine dendrimer conjugate with glucuronylglucosyl-β-cyclodextrin (G3) as a novel carrier for siRNA  J Drug Target  2014  22(10):927-34  PubMed ID: 25148608   DOI: 10.3109/1061186X.2014.950663
19516  Motoyama K, Mitsuyasu R, Akao C, Tanaka T, Ohyama A, Sato N, Higashi T, Arima H.  Design and evaluation of thioalkylated mannose-modified dendrimer (G3)/α-cyclodextrin conjugates as antigen-presenting cell-selective siRNA carriers  AAPS J  2014  16(6):1298-308  PubMed ID: 25236864   DOI: 10.1208/s12248-014-9665-9
19523  Kono Y, Kawakami S, Higuchi Y, Yamashita F, Hashida M.  In vitro evaluation of inhibitory effect of nuclear factor-kappaB activity by small interfering RNA on pro-tumor characteristics of M2-like macrophages  Biol Pharm Bull  2014  37(1):137-44  PubMed ID: 24141263   DOI: 10.1248/bpb.b13-00659
19524  Migita K, Sho M, Shimada K, Yasuda S, Yamato I, Takayama T, Matsumoto S, Wakatsuki K, Hotta K, Tanaka T, Ito M, Konishi N, Nakajima Y.  Significant involvement of herpesvirus entry mediator in human esophageal squamous cell carcinoma  Cancer  2014  120(6):808-17.  PubMed ID: 24249528   DOI: 10.1002/cncr.28491
15819  Gong ZY, Kidoya H, Mohri T, Han Y, Takakura N.  DNA damage enhanced by the attenuation of SLD5 delays cell cycle restoration in normal cells but not in cancer cells  PLoS One  2014  21;9(10):e110483  PubMed ID: 25334017   DOI: 10.1371/journal.pone.0110483
16092  Hałupka-Bryl M, Asai K, Thangavel S, Bednarowicz M, Krzyminiewski R, Nagasaki Y.  Synthesis and in vitro and in vivo evaluations of poly(ethylene glycol)-block-poly(4-vinylbenzylphosphonate) magnetic nanoparticles containing doxorubicin as a potential targeted drug delivery system  Colloids Surf B Biointerfaces  2014  118:140-7  PubMed ID: 24769390   DOI: 10.1016/j.colsurfb.2014.03.025
16093  Kono Y, Kawakami S, Higuchi Y, Maruyama K, Yamashita F, Hashida M.  Tumour-associated macrophages targeted transfection with NF-κB decoy/mannose-modified bubble lipoplexes inhibits tumour growth in tumour-bearing mice  J Drug Target  2014  22(5):439-49  PubMed ID: 24579693   DOI: 10.3109/1061186X.2014.880443
17153  Haga E, Endo Y, Haruta M, Koba C, Matsumura K, Takamatsu K, Ikeda T, Nishimura Y, Senju S.  Therapy of peritoneally disseminated colon cancer by TAP-deficient embryonic stem cell-derived macrophages in allogeneic recipients  J Immunol  2014  193(4):2024-33  PubMed ID: 25031460   DOI: 10.4049/jimmunol.1303473
18594  Yasuda S, Sho M, Yamato I, Yoshiji H, Wakatsuki K, Nishiwada S, Yagita H, Nakajima Y.  Simultaneous blockade of programmed death 1 and vascular endothelial growth factor receptor 2 (VEGFR2) induces synergistic anti-tumour effect in vivo  Clin Exp Immunol  2013  172(3):500-6  PubMed ID: 23600839   DOI: 10.1111/cei.12069
19520  Asano R, Nagami A, Fukumoto Y, Yazama F, Ito H, Sakata I, Tai A.  Synthesis and biological evaluation of new chlorin derivatives as potential photosensitizers for photodynamic therapy  Bioorg Med Chem  2013  21(8):2298-2304  PubMed ID: 23477944   DOI: 10.1016/j.bmc.2013.02.005
19526  Miyauchi E, Ogita T, Miyamoto J, Kawamoto S, Morita H, Ohno H, Suzuki T, Tanabe S.  Bifidobacterium longum alleviates dextran sulfate sodium-induced colitis by suppressing IL-17A response: involvement of intestinal epithelial costimulatory molecules  PLoS One  2013  8(11):e79735  PubMed ID: 24255712   DOI: 10.1371/journal.pone.0079735
9089  Ryoko Yumoto, Saki Kakizoe, Junya Nagai, Denpong Patanasethanont, Bung-Orn Sripanidkulchai, Mikihisa Takano  Flow Cytometry Analysis of Cancer Cell Death Induced by the Extract of Thai Plant Ellipeiopsis Cherrevensis  Drug Metab Pharmacokinet  2013  28 (2), 159-63  PubMed ID: 22850758   DOI: 10.2133/dmpk.dmpk-12-nt-056
15985  Kokuryo D, Anraku Y, Kishimura A, Tanaka S, Kano MR, Kershaw J, Nishiyama N, Saga T, Aoki I, Kataoka K.  SPIO-PICsome: development of a highly sensitive and stealth-capable MRI nano-agent for tumor detection using SPIO-loaded unilamellar polyion complex vesicles (PICsomes)  J Control Release  2013  169(3):220-7  PubMed ID: 23542239   DOI: 10.1016/j.jconrel.2013.03.016
16084  Murayama S , Jo JI , Shibata Y , Liang K , Santa T , Saga T , Aoki I , Kato M .  The simple preparation of polyethylene glycol-based soft nanoparticles containing dual imaging probes  J Mater Chem B  2013  1(38):4932-4938  PubMed ID: 32261082   DOI: 10.1039/c3tb20828a
19518  Motoyama K, Hayashida K, Higashi T, Arima H.  Polypseudorotaxanes of pegylated α-cyclodextrin/polyamidoamine dendrimer conjugate with cyclodextrins as a sustained release system for DNA  Bioorg Med Chem  2012  20(4):1425-33  PubMed ID: 22277591   DOI: 10.1016/j.bmc.2011.12.060
19522  Arima H, Yoshimatsu A, Ikeda H, Ohyama A, Motoyama K, Higashi T, Tsuchiya A, Niidome T, Katayama Y, Hattori K, Takeuchi T.  Folate-PEG-appended dendrimer conjugate with α-cyclodextrin as a novel cancer cell-selective siRNA delivery carrier  Mol Pharm  2012  9(9):2591-604  PubMed ID: 22873579   DOI: 10.1021/mp300188f
19527  The apelin/APJ system induces maturation of the tumor vasculature and improves the efficiency of immune therapy  The apelin/APJ system induces maturation of the tumor vasculature and improves the efficiency of immune therapy  Oncogene  2012  31(27):3254-64  PubMed ID: 22037214   DOI: 10.1038/onc.2011.489
16077  Kei Asai, Naoki Kanayama, Yukio Nagasaki  Preparation and evaluation of highly dispersible and Ca2+ level responsive PEGylated calcium phosphate nanoparticle with PEG-block-poly(4-vinylbenzylphosphonate) for the application of drug carrier  Transactions of the Materials Research Society of Japan  2012  37:337-340    DOI: 10.14723/tmrsj.37.337
7692  Arima H, Tsutsumi T, Yoshimatsu A, Ikeda H, Motoyama K, Higashi T, Hirayama F, Uekama K.  Inhibitory effect of siRNA complexes with polyamidoamine dendrimer/α-cyclodextrin conjugate (generation 3, G3) on endogenous gene expression.  Eur J Pharm Sci  2011  44:375-84  PubMed ID: 21896329   DOI: 10.1016/j.ejps.2011.08.019
7811  Azuma H, Aizawa Y, Higashitani N, Tsumori T, Kojima-Yuasa A, Matsui-Yuasa I, Nagasaki T.  Biological activity of water-soluble inclusion complexes of 1'-acetoxychavicol acetate with cyclodextrins.  Bioorg. Med. Chem.  2011  19:3855-63  PubMed ID: 21596572   DOI: 10.1016/j.bmc.2011.04.038
19528  Habeeb BS, Kitayama J, Nagawa H.  Adiponectin supports cell survival in glucose deprivation through enhancement of autophagic response in colorectal cancer cells  Cancer Sci  2011  102(5):999-1006  PubMed ID: 21299716   DOI: 10.1111/j.1349-7006.2011.01902.x
15358  Yoriki R, Akashi S, Sho M, Nomi T, Yamato I, Hotta K, Takayama T, Matsumoto S, Wakatsuki K, Migita K, Yagita H, Nakajima Y.  Therapeutic potential of the TWEAK/Fn14 pathway in intractable gastrointestinal cancer  Exp Ther Med  2011  2(1):103-108  PubMed ID: 22977477   DOI: 10.3892/etm.2010.181
8168  Yoshikawa K, Kokudo N, Hashimoto T, Yamamoto K, Inose T, Kimura T.  Novel phthalide compounds from Sparassis crispa (Hanabiratake), Hanabiratakelide A-C, exhibiting anti-cancer related activity.  Biol. Pharm. Bull.  2010  33:1355-9  PubMed ID: 20686231   DOI: 10.1248/bpb.33.1355
8283  Matsumura K, Bae JY, Hyon SH.  Polyampholytes as cryoprotective agents for mammalian cell cryopreservation.  Cell Transplant  2010  19(6):691-9  PubMed ID: 20525437   DOI: 10.3727/096368910X508780

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