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Cell No. : Cell Name
RCB2657 : Colon-26  update : 2022/03/09
CommentMouse cell line derived from colon cancer. BALB/c strain. TKG0518 (Deposited from Tohoku Univ.).
Comment from the depositor
Terms and conditionsThere is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC.
Order Form Order Form(C-0005.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)  
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (
Basic information Depositor Fukuda, Hiroshi
Year of deposit 2007
Original cell TKG0518
Animal mouse < Mammals
Strain name BALB/c
Tissue rectum
Disease name Rectum carcinoma
Classification cancer
History Cell Resource Center for Biomedical Research, Tohoku University(TKG0518)
Memo_1 A culture submitted to the CRCBR, Tohoku University was found to be contaminated with mycoplasma. Mycoplasma was eliminated with BM Cycline and MC210 at the CRCBR.
Lifespan infinite
Morphology fibroblast-like
Cellosaurus(Expasy) CVCL_0240
deposit info
lot info
Medium Medium List
Culture type Adherent cells
Medium and additives RPMI1640 + 10% FBS
Antibiotics Free
Passage method 0.25% Trypsin
Culture information Passage ratio 1 : 8 split
SC frequency Subculture : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
Animal PCR OK
SSLP(mouse) OK
Isozyme LD, NP
deposit info
lot info
Reference information Reference 1
User's Publication 98

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5251  Corbett TH, Griswold DP Jr, Roberts BJ, Peckham JC, Schabel FM Jr.  Tumor induction relationships in development of transplantable cancers of the colon in mice for chemotherapy assays, with a note on carcinogen structure.  Cancer Res  1975  35(9):2434-9  PubMed ID: 1149045

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User's Publication
20380  Ma L, Sakamoto Y, Ando K, Fujita H, Takahashi A, Takeshima T, Otsuka H, Ebner DK, Kakimi K, Imai T, Shimokawa T.  Th balance related host genetic background affects the therapeutic effects of combining carbon-ion radiotherapy with dendritic cell immunotherapy.  Int J Radiat Oncol Biol Phys  2022    PubMed ID: 34740767
20139  mam SE, Elsadek NE, Abu Lila AS, Takata H, Kawaguchi Y, Shimizu T, Ando H, Ishima Y, Ishida T.  Anti-PEG IgM production and accelerated blood clearance phenomenon after the administration of PEGylated exosomes in mice.  J Control Release  2021  334:327-334  PubMed ID: 33957196
14342  Ando H, Emam SE, Kawaguchi Y, Shimizu T, Ishima Y, Eshima K, Ishida T.  Increasing Tumor Extracellular pH by an Oral Alkalinizing Agent Improves Antitumor Responses of Anti-PD-1 Antibody: Implication of Relationships between Serum Bicarbonate Concentrations, Urinary pH, and Therapeutic Outcomes  Biol Pharm Bull  2021  44(6):844-852  PubMed ID: 34078817
15150  Morinaga M, Sako N, Isobe M, Lee-Hotta S, Sugiura H, Kametaka S.  Aerobic Exercise Ameliorates Cancer Cachexia-Induced Muscle Wasting through Adiponectin Signaling  Int J Mol Sci  2021  22(6):3110  PubMed ID: 33803685
20320  Kitaoka Y, Miyazaki M, Kikuchi S.  Voluntary exercise prevents abnormal muscle mitochondrial morphology in cancer cachexia mice.  Physiol Rep  2021  9(16):e15016  PubMed ID: 34427401
16067  Lazarova D, Semkova S, Zlateva G, Tatsuya H, Aoki I, Bakalova R.  Quantum Sensors To Track Total Redox-Status and Oxidative Stress in Cells and Tissues Using Electron-Paramagnetic Resonance, Magnetic Resonance Imaging, and Optical Imaging  Anal Chem  2021  93(5):2828-2837  PubMed ID: 33508934
16096  Sato Y, Fu Y, Liu H, Lee MY, Shaw MH.  Tumor-immune profiling of CT-26 and Colon 26 syngeneic mouse models reveals mechanism of anti-PD-1 response  BMC Cancer  2021  21(1):122  PubMed ID: 34774008
16121  Sano K, Ishida Y, Tanaka T, Mizukami T, Nagayama T, Haratake Y, Munekane M, Yamasaki T, Mukai T.  Enhanced Delivery of Thermoresponsive Polymer-Based Medicine into Tumors by Using Heat Produced from Gold Nanorods Irradiated with Near-Infrared Light  Cancers (Basel)  2021  13(19):5005  PubMed ID: 34638489
11792  Mimura A, Inaoka Y, Asakawa S, Murase K.  A Novel Cellular Imaging Method Using Hemagglutinating Virus of Japan-Envelope (HVJ-E) Vector and Magnetic Particle Imaging.  J Nanosci Nanotechnol  2020    PubMed ID: 31492206
12035  Kitao A, Kawamoto S, Kurata K, Hayakawa I, Yamasaki T, Matsuoka H, Sumi Y, Kakeji Y, Kamesaki T, Minami H.  Band 3 ectopic expression in colorectal cancer induces an increase in erythrocyte membrane-bound IgG and may cause immune-related anemia.  Int. J. Hematol.  2020    PubMed ID: 31997080
12327  Mahib MR, Hosojima S, Kushiyama H, Kinoshita T, Shiroishi T, Suda T, Tsuchiya K.  Caspase-7 mediates caspase-1-induced apoptosis independently of Bid  Microbiol Immunol  2020  64(2):143-152  PubMed ID: 31687791
13004  Yamada T, Ashida Y, Tatebayashi D, Abe M, Himori K.  Cancer Cachexia Induces Preferential Skeletal Muscle Myosin Loss When Combined With Denervation.  Front Physiol  2020    PubMed ID: 32425814
13266  Nomura S, Takahashi M, Kato AH, Wada Y, Watanabe Y, Yamashita F, Mukai H.  Biosorption-based 64Cu-labeling of bacteria for pharmacokinetic positron-emission tomography.  Int J Pharm  2020    PubMed ID: 33027635
13300  Takayama T, Shimizu T, Lila ASA, Kanazawa Y, Ando H, Ishima Y, Ishida T.  Adjuvant Antitumor Immunity Contributes to the Overall Antitumor Effect of Pegylated Liposomal Doxorubicin (Doxil®) in C26 Tumor-Bearing Immunocompetent Mice.  Pharmaceutics  2020    PubMed ID: 33086690
13584  Uda RM, Yoshida N, Iwasaki T, Hayashi K.  pH-triggered solubility and cytotoxicity changes of malachite green derivatives incorporated in liposomes for killing cancer cells  J Mater Chem B  2020  8(36):8242-8248  PubMed ID: 32794526
13603  Imanishi M, Yamakawa Y, Fukushima K, Ikuto R, Maegawa A, Izawa-Ishizawa Y, Horinouchi Y, Kondo M, Kishuku M, Goda M, Zamami Y, Takechi K, Chuma M, Ikeda Y, Tsuchiya K, Fujino H, Tsuneyama K, Ishizawa K.  Fibroblast-specific ERK5 deficiency changes tumor vasculature and exacerbates tumor progression in a mouse model  Naunyn Schmiedebergs Arch Pharmacol  2020  393(7):1239-1250.  PubMed ID: 32307577
13631  Mei T, Shashni B, Maeda H, Nagasaki Y.  Fibrinolytic tissue plasminogen activator installed redox-active nanoparticles (t-PA@iRNP) for cancer therapy  Biomaterials  2020  259:120290  PubMed ID: 32829147
15161  Kudláčová J, Kotrchová L, Kostka L, Randárová E, Filipová M, Janoušková O, Fang J, Etrych T.  Structure-to-Efficacy Relationship of HPMA-Based Nanomedicines: The Tumor Spheroid Penetration Study  Pharmaceutics  2020  12(12):1242  PubMed ID: 33419291
11341  Fukuda T, Nanjo Y, Fujimoto M, Yoshida K, Natsui Y, Ishibashi F, Okazaki F, To H, Iwao M.  Lamellarin-inspired potent topoisomerase I inhibitors with the unprecedented benzo[g][1]benzopyrano[4,3-b]indol-6(13H)-one scaffold.  Bioorg. Med. Chem.  2019    PubMed ID: 30553626
4573  Hatai M, Horiyama S, Yoshikawa N, Kinoshita E, Kagota S, Shinozuka K, Nakamura K.  trans-2-Pentenal, an Active Compound in Cigarette Smoke, Identified via Its Ability to Form Adducts with Glutathione.  Chem Pharm Bull (Tokyo)  2019  67(9):1000-1005  PubMed ID: 31474722
11506  Hayashi K, Watanabe M, Iwasaki T, Shudou M, Uda RM.  Endosomal escape by photo-activated fusion of liposomes containing a malachite green derivative: a novel class of photoresponsive liposomes for drug delivery vehicles.  Photochem. Photobiol. Sci.  2019    PubMed ID: 30964475
11509  Zhelev Z, Georgieva E, Lazarova D, Semkova S, Aoki I, Gulubova M, Higashi T, Bakalova R.  Redox Imaging to Distinguish Cells with Different Proliferative Indexes: Superoxide, Hydroperoxides, and Their Ratio as Potential Biomarkers.  Oxid Med Cell Longev  2019    PubMed ID: 31089411
11530  Uda RM, Nishimoto N, Matsui T, Takagi S.  Photoinduced binding of malachite green copolymer to parallel G-quadruplex DNA.  Soft Matter  2019    PubMed ID: 31073583
11539  Suzuka H, Mimura A, Inaoka Y, Murase K.  Magnetic Nanoparticles in Macrophages and Cancer Cells Exhibit Different Signal Behavior on Magnetic Particle Imaging.  J Nanosci Nanotechnol  2019    PubMed ID: 31039837
11546  Tsuchiya K, Nakajima S, Hosojima S, Thi Nguyen D, Hattori T, Manh Le T, Hori O, Mahib MR, Yamaguchi Y, Miura M, Kinoshita T, Kushiyama H, Sakurai M, Shiroishi T, Suda T.  Caspase-1 initiates apoptosis in the absence of gasdermin D.  Nat Commun  2019    PubMed ID: 31064994
11603  Aoki N, Matsui Y.  Comprehensive Analysis of Mouse Cancer/Testis Antigen Functions in Cancer Cells and Roles of TEKT5 in Cancer Cells and Testicular Germ Cells.  Mol. Cell. Biol.  2019    PubMed ID: 31208979
11847  Matsui S, Kataoka H, Tanaka JI, Kikuchi M, Fukamachi H, Morisaki H, Matsushima H, Mishima K, Hironaka S, Takaki T, Okahashi N, Maruoka Y, Kuwata H.  Dysregulation of intestinal microbiota elicited by food allergy induces IgA-mediated oral dysbiosis.  Infect. Immun.  2019    PubMed ID: 31611274
11859  Emam SE, Selim Abu Lila A, Elsadek NE, Ando H, Shimizu T, Okuhira K, Ishima Y, Mahdy MA, Ghazy FS, Ishid T.  Cancer cell-type tropism is one of crucial determinants for the efficient systemic delivery of cancer cell-derived exosomes to tumor tissues.  Eur J Pharm Biopharm  2019    PubMed ID: 31629787
9811  Eiji Kasumi, Norifumi Sato  A Ketogenic Diet Improves the Prognosis in a Mouse Model of Peritoneal Dissemination Without Tumor Regression  J Clin Biochem Nutr   2019  64(3):201-208  PubMed ID: 31138953
10421  Yoshimi Inaoka, Tamami Keii, Atsushi Mimura, Kenya Murase  A Novel Therapeutic Strategy Combining Use of Intracellular Magnetic Nanoparticles under an Alternating Magnetic Field and Bleomycin  Open Journal of Applied Sciences  2019  9, Article ID:91110,17 
10589  Seiji Komeda, Masako Uemura, Hiroki Yoneyama, Shinya Harusawa and Keiichi Hiramoto  In Vitro Cytotoxicity and In Vivo Antitumor Efficacy of Tetrazolato-Bridged Dinuclear Platinum(II) Complexes with a Bulky Substituent at Tetrazole C5  Inorganics  2019  7(1):5 
12407  Peng JQ, Fumoto S, Suga T, Miyamoto H, Kuroda N, Kawakami S, Nishida K.  Targeted co-delivery of protein and drug to a tumor in vivo by sophisticated RGD-modified lipid-calcium carbonate nanoparticles  J Control Release  2019  302:42-53  PubMed ID: 30926479
12408  Cancer therapy with major histocompatibility complex-deficient and interferon β-producing myeloid cells derived from allogeneic embryonic stem cells  Cancer therapy with major histocompatibility complex-deficient and interferon β-producing myeloid cells derived from allogeneic embryonic stem cells  Cancer Sci  2019  110(10):3027-3037  PubMed ID: 31348591
12409  Yamamoto S, Yamashita T, Ito M, Caaveiro JMM, Egashira N, Tozaki-Saitoh H, Tsuda M.  New pharmacological effect of fulvestrant to prevent oxaliplatin-induced neurodegeneration and mechanical allodynia in rats  Int J Cancer   2019  145(8):2107-2113  PubMed ID: 30515800
14891  Kohei Sano, Ling Bao, Natsuka Suzuno, Kento Kannaka, Toshihide Yamasaki, Masayuki Munekane, Takahiro Mukai  Development of Cancer-Targeted Single Photon Emission Computed Tomography/Fluorescence Dual Imaging Probe Based on Polyoxazoline  ACS Applied Polymer Materials  2019  1:953-958 
10546  Miyamoto H, Tsujimoto H, Horii T, Ozamoto Y, Ueda J, Takagi T, Saitoh N, Hagiwara A.  The influences of a novel anti-adhesion device, thermally cross-linked gelatin film on peritoneal dissemination of tumor cells: The in vitro and in vivo experiments using murine carcinomatous peritonitis models.  J. Biomed. Mater. Res. Part B Appl. Biomater.  2018  106(6):2122-2130  PubMed ID: 29024447
10733  Kawami M, Yamada Y, Issarachot O, Junyaprasert VB, Yumoto R, Takano M.  P-gp modulating effect of Azadirachta indica extract in multidrug-resistant cancer cell lines.  Pharmazie  2018  73:104-109  PubMed ID: 29442013
10746  Miura K, Haraguchi M, Ito H, Tai A.  Potential Antitumor Activity of 2-O-α-d-Glucopyranosyl-6-O-(2-Pentylheptanoyl)-l-Ascorbic Acid.  Int J Mol Sci  2018  19:  PubMed ID: 29439410
10772  Morio H, Sun Y, Harada M, Ide H, Shimozato O, Zhou X, Higashi K, Yuki R, Yamaguchi N, Hofbauer JP, Guttmann-Gruber C, Anzai N, Akita H, Chiba K, Furihata T.  Cancer-Type OATP1B3 mRNA in Extracellular Vesicles as a Promising Candidate for a Serum-Based Colorectal Cancer Biomarker.  Biol. Pharm. Bull.  2018  41:445-449  PubMed ID: 29491222
10827  Hatai M, Yoshikawa N, Kinoshita E, Horiyama S, Kagota S, Shinozuka K, Nakamura K.  Invasion-inhibiting Effects of Gaseous Components in Cigarette Smoke on Mouse Rectal Carcinoma Colon-26 Cells.  In Vivo  2018  32:493-497  PubMed ID: 29695551
10831  Emam SE, Ando H, Abu Lila AS, Shimizu T, Ukawa M, Okuhira K, Ishima Y, Mahdy MA, Ghazy FS, Ishida T.  A Novel Strategy to Increase the Yield of Exosomes (Extracellular Vesicles) for an Expansion of Basic Research.  Biol. Pharm. Bull.  2018  41:733-742  PubMed ID: 29709910
11060  Hayashi K, Mitsuyoshi Y, Kamei T, Shimanouchi T, Suga K, Okamoto Y, Nakamura H, Umakoshi H.  Design of Pyrene–Fatty Acid Conjugates for Real-Time Monitoring of Drug Delivery and Controllability of Drug Release  ACS Omega  2018  3:3572-3580  PubMed ID: 30023872
11199  Kuroda K, Yamashita M, Murahata Y, Azuma K, Osaki T, Tsuka T, Ito N, Imagawa T, Okamoto Y.  Use of ozonated water as a new therapeutic approach to solve current concerns around antitumor treatment.  Exp Ther Med  2018  16(3):1597-1602  PubMed ID: 30186377
11187  Noji M, So M, Yamaguchi K, Hojo H, Onda M, Akazawa-Ogawa Y, Hagihara Y, Goto Y.  Heat-Induced Aggregation of Hen Ovalbumin Suggests a Key Factor Responsible for Serpin Polymerization.  Biochemistry  2018  57(37):5415-5426  PubMed ID: 30148614
11224  Emam SE, Ando H, Lila ASA, Shimizu T, Okuhira K, Ishima Y, Mahdy MA, Ghazy FS, Sagawa I, Ishida T.  Liposome co-incubation with cancer cells secreted exosomes (extracellular vesicles) with different proteins expressions and different uptake pathways.  Sci Rep  2018    PubMed ID: 30262875
4079    Bleomycin-Loaded pH-Sensitive Polymer–Lipid-Incorporated Liposomes for Cancer Chemotherapy  Polymers  2018  10, 74 
4179  Tatebayashi D, Himori K, Yamada R, Ashida Y, Miyazaki M, Yamada T.  High-intensity eccentric training ameliorates muscle wasting in colon 26 tumor-bearing mice.  PLoS ONE  2018    PubMed ID: 29894511
14600  Sano K, Kanada Y, Takahashi K, Ding N, Kanazaki K, Mukai T, Ono M, Saji H.  Enhanced Delivery of Radiolabeled Polyoxazoline into Tumors via Self-Aggregation under Hyperthermic Conditions  Mol Pharm  2018  15(9):3997-4003  PubMed ID: 30036483
10278  Miura K, Tai A.  2-O-α-D-Glucopyranosyl-l-ascorbic acid as an antitumor agent for infusion therapy.  Biochem Biophys Rep  2017  10:232-236  PubMed ID: 28955751
10424  Maeda M, Muragaki Y, Okamoto J, Yoshizawa S, Abe N, Nakamoto H, Ishii H, Kawabata K, Umemura S, Nishiyama N, Kataoka K, Iseki H.  Sonodynamic Therapy Based on Combined Use of Low Dose Administration of Epirubicin-Incorporating Drug Delivery System and Focused Ultrasound.  Ultrasound Med Biol  2017  43:2295-2301  PubMed ID: 28705555
10545  Ikemura M, Hashida T.  Effect of Hyperglycemia on Antitumor Activity and Survival in Tumor-bearing Mice Receiving Oxaliplatin and Fluorouracil.  Anticancer Res.  2017  37:5463-5468  PubMed ID: 28982857
10991  AKIKO OHKI, MINORI TANOUE, SAYUMI KOBAYASHI, KENYA MURASE  Magnetic Particle Imaging for Quantitative Evaluation of Tumor Response to Magnetic Hyperthermia Treatment Combined with Chemotherapy Using Cisplatin  Thermal Medicine  2017  33, 39-51 
11017    Comparative Study of Extracellular and Intracellular Magnetic Hyperthermia Treatments Using Magnetic Particle Imaging  Open Journal of Applied Sciences  2017  7, 647-660 
5395  Kokuryo D, Aoki I, Yuba E, Kono K, Aoshima S, Kershaw J, Saga T.  Evaluation of a combination tumor treatment using thermo-triggered liposomal drug delivery and carbon ion irradiation.  Transl Res  2017  185:24-33  PubMed ID: 28482173
10855  Shimaoka H, Takeno S, Maki K, Sasaki T, Hasegawa S, Yamashita Y.  A cytokine signal inhibitor for rheumatoid arthritis enhances cancer metastasis via depletion of NK cells in an experimental lung metastasis mouse model of colon cancer  Oncol Lett  2017  14(3):3019-3027  PubMed ID: 28928840
14669  Gao Z, Nakanishi Y, Noda S, Omachi H, Shinohara H, Kimura H, Nagasaki Y.  Development of Gd 3 N@C 80 encapsulated redox nanoparticles for high-performance magnetic resonance imaging  J Biomater Sci Polym Ed  2017  28(10-12):1036-1050  PubMed ID: 28132586
14719  Sano K, Ohashi M, Kanazaki K, Makino A, Ding N, Deguchi J, Kanada Y, Ono M, Saji H.  Indocyanine Green-Labeled Polysarcosine for in Vivo Photoacoustic Tumor Imaging  Bioconjug Chem  2017  28(4):1024-1030  PubMed ID: 28166625
14720  Ohyama A, Higashi T, Motoyama K, Arima H.  Ternary complexes of folate-PEG-appended dendrimer (G4)/α-cyclodextrin conjugate, siRNA and low-molecular-weight polysaccharide sacran as a novel tumor-selective siRNA delivery system  Int J Biol Macromol  2017  99:21-28  PubMed ID: 28223132
14721  Miki K, Enomoto A, Inoue T, Nabeshima T, Saino S, Shimizu S, Matsuoka H, Ohe K.  Polymeric Self-Assemblies with Boron-Containing Near-Infrared Dye Dimers for Photoacoustic Imaging Probes  Biomacromolecules  2017  18(1):249-256  PubMed ID: 27936606
14722  Kanemaru H, Yamane F, Fukushima K, Matsuki T, Kawasaki T, Ebina I, Kuniyoshi K, Tanaka H, Maruyama K, Maeda K, Satoh T, Akira S.  Antitumor effect of Batf2 through IL-12 p40 up-regulation in tumor-associated macrophages  Proc Natl Acad Sci U S A  2017  114(35):E7331-E7340  PubMed ID: 28808017
14736  Takara K, Eino D, Ando K, Yasuda D, Naito H, Tsukada Y, Iba T, Wakabayashi T, Muramatsu F, Kidoya H, Fukuhara S, Mochizuki N, Ishii S, Kishima H, Takakura N.  Lysophosphatidic Acid Receptor 4 Activation Augments Drug Delivery in Tumors by Tightening Endothelial Cell-Cell Contact  Cell Rep  2017  20(9):2072-2086  PubMed ID: 28854359
14748  Yamamoto S, Ushio S, Egashira N, Kawashiri T, Mitsuyasu S, Higuchi H, Ozawa N, Masuguchi K, Ono Y, Masuda S.  Excessive spinal glutamate transmission is involved in oxaliplatin-induced mechanical allodynia: a possibility for riluzole as a prophylactic drug  Sci Rep  2017  7(1):9661  PubMed ID: 28851920
7141  Vong LB, Nagasaki Y.  Combination Treatment of Murine Colon Cancer with Doxorubicin and Redox Nanoparticles.  Mol. Pharm.  2016  13:449-55  PubMed ID: 26605906
7209  Osaki T, Yokoe I, Uto Y, Ishizuka M, Tanaka T, Yamanaka N, Kurahashi T, Azuma K, Murahata Y, Tsuka T, Ito N, Imagawa T, Okamoto Y.  Bleomycin enhances the efficacy of sonodynamic therapy using aluminum phthalocyanine disulfonate.  Ultrason Sonochem  2016  28:161-168  PubMed ID: 26384895
9507  Ohyama A, Higashi T, Motoyama K, Arima H.  In Vitro and In Vivo Tumor-Targeting siRNA Delivery Using Folate-PEG-appended Dendrimer (G4)/α-Cyclodextrin Conjugates.  Bioconjug. Chem.  2016  27:521-32  PubMed ID: 26715308
9753  Gao Z, Horiguchi Y, Nakai K, Matsumura A, Suzuki M, Ono K, Nagasaki Y.  Use of boron cluster-containing redox nanoparticles with ROS scavenging ability in boron neutron capture therapy to achieve high therapeutic efficiency and low adverse effects.  Biomaterials  2016  104:201-12  PubMed ID: 27467416
9856  Kanazaki K, Sano K, Makino A, Homma T, Ono M, Saji H.  Polyoxazoline multivalently conjugated with indocyanine green for sensitive in vivo photoacoustic imaging of tumors.  Sci Rep  2016  6:33798  PubMed ID: 27667374
9995  Yamano T, Kubo S, Fukumoto M, Yano A, Mawatari-Furukawa Y, Okamura H, Tomita N.  Whole cell vaccination using immunogenic cell death by an oncolytic adenovirus is effective against a colorectal cancer model.  Mol Ther Oncolytics  2016  3:16031  PubMed ID: 28035331
10859  Tomomi Kuboyabu, Isamu Yabata, Marina Aoki, Natsuo Banura, Kohei Nishimoto, Atsushi Mimura, Kenya Murase  Magnetic Particle Imaging for Magnetic Hyperthermia Treatment: Visualization and Quantification of the Intratumoral Distribution and Temporal Change of Magnetic Nanoparticles in Vivo  Open Journal of Medical Imaging  2016  6:1-15 
10896  Tomomi Kuboyabu, Mikiko Yamawaki, Marina Aoki, Akiko Ohki, Kenya Murase   Quantitative Evaluation of Tumor Early Response to Magnetic Hyperthermia combined with Vascular Disrupting Therapy using Magnetic Particle Imaging  International Journal of Nanomedicine and Nanosurgery  2016  2.3 
12406  Akiko Ohki, Tomomi Kuboyabu, Marina Aoki, Mikiko Yamawaki, Kenya Murase  Quantitative Evaluation of Tumor Response to combination of Magnetic Hyperthermia Treatment and Radiation Therapy using Magnetic Particle Imaging  Int J Nanomed Nanosurg  2016  2.3 
12691  Suzuki R, Oda Y, Omata D, Nishiie N, Koshima R, Shiono Y, Sawaguchi Y, Unga J, Naoi T, Negishi Y, Kawakami S, Hashida M, Maruyama K.  Tumor growth suppression by the combination of nanobubbles and ultrasound  Cancer Sci  2016  107(3):217-23  PubMed ID: 26707839
14132  Okazaki F, Matsunaga N, Okazaki H, Azuma H, Hamamura K, Tsuruta A, Tsurudome Y, Ogino T, Hara Y, Suzuki T, Hyodo K, Ishihara H, Kikuchi H, To H, Aramaki H, Koyanagi S, Ohdo S.  Circadian Clock in a Mouse Colon Tumor Regulates Intracellular Iron Levels to Promote Tumor Progression  J Biol Chem  2016  291(13):7017-28  PubMed ID: 26797126
7116  Hayashi K, Kiriishi M, Suga K, Okamoto Y, Umakoshi H.  Investigation of Fatty Acid Ketohydrazone Modified Liposome's Properties as a Drug Carrier.  J Drug Deliv  2015  2015:481670  PubMed ID: 26649201
7167  Kuroda K, Azuma K, Mori T, Kawamoto K, Murahata Y, Tsuka T, Osaki T, Ito N, Imagawa T, Itoh F, Okamoto Y.  The Safety and Anti-Tumor Effects of Ozonated Water in Vivo.  Int J Mol Sci  2015  16:25108-20  PubMed ID: 26506343
7195  Narayanan NK, Kunimasa K, Yamori Y, Mori M, Mori H, Nakamura K, Miller G, Manne U, Tiwari AK, Narayanan B.  Antitumor activity of melinjo (Gnetum gnemon L.) seed extract in human and murine tumor models in vitro and in a colon-26 tumor-bearing mouse model in vivo.  Cancer Med  2015  4:1767-80  PubMed ID: 26408414
7261  Aikawa T, Ito S, Shinohara M, Kaneko M, Kondo T, Yuasa M.  A drug formulation using an alginate hydrogel matrix for efficient oral delivery of the manganese porphyrin-based superoxide dismutase mimic.  Biomater Sci  2015  3:861-9  PubMed ID: 26221846
7364  Arai Y, Yamamoto T, Minamikawa T, Takamatsu T, Nagai T.  Spectral fingerprinting of individual cells visualized by cavity-reflection-enhanced light-absorption microscopy.  PLoS ONE  2015  10:e0125733  PubMed ID: 25950513
7366  Vong LB, Yoshitomi T, Matsui H, Nagasaki Y.  Development of an oral nanotherapeutics using redox nanoparticles for treatment of colitis-associated colon cancer.  Biomaterials  2015  55:54-63  PubMed ID: 25934452
7555  Ryota Araki, Shoji Nishida, Yosuke Hiraki, Takeshi Yabe  Kamikihito ameliorates tumor‐induced sickness behavior in mice.  Traditional & Kampo Medicine  2015  2:93-96 
7571  Y. Miura, A. B. Tsuji, A. Sugyo, H. Sudo, I. Aoki, M. Inubushi, M. Yashiro, K. Hirakawa, H. Cabral, N. Nishiyama, T. Saga, K. Kataoka  Polymeric Micelle Platform for Multimodal Tomographic Imaging to Detect Scirrhous Gastric Cancer.  ACS Biomater Sci Eng  2015  1:1067?1076 
12246  Kaori Miura, Futoshi Yazama, Akihiro Tai  Oxidative stress-mediated antitumor activity of erythorbic acid in high doses  Biochem Biophys Rep  2015  3:117-122  PubMed ID: 29124174
15071  Shinya T, Yokota T, Nakayama S, Oki S, Mutoh J, Takahashi S, Sato K.  Orally Administered Mucolytic Drug l-Carbocisteine Inhibits Angiogenesis and Tumor Growth in Mice  J Pharmacol Exp Ther  2015  354(3):269-78  PubMed ID: 26126534
11037  Takemura R, Takaki H, Okada S, Shime H, Akazawa T, Oshiumi H, Matsumoto M, Teshima T, Seya T.  PolyI:C-Induced, TLR3/RIP3-Dependent Necroptosis Backs Up Immune Effector-Mediated Tumor Elimination In Vivo  Cancer Immunol Res  2015  3(8):902-14  PubMed ID: 25898986
15236  Kudo S, Nagasaki Y.  A novel nitric oxide-based anticancer therapeutics by macrophage-targeted poly(l-arginine)-based nanoparticles  J Control Release  2015  217:256-62  PubMed ID: 26386436
15437  Miki K, Inoue T, Kobayashi Y, Nakano K, Matsuoka H, Yamauchi F, Yano T, Ohe K.  Near-infrared dye-conjugated amphiphilic hyaluronic acid derivatives as a dual contrast agent for in vivo optical and photoacoustic tumor imaging  Biomacromolecules  2015  16(1):219-27  PubMed ID: 25402751
15481  Fujita S, Ushio S, Ozawa N, Masuguchi K, Kawashiri T, Oishi R, Egashira N.  Exenatide Facilitates Recovery from Oxaliplatin-Induced Peripheral Neuropathy in Rats  PLoS One  2015  10(11):e0141921  PubMed ID: 26536615
15819  Gong ZY, Kidoya H, Mohri T, Han Y, Takakura N.  DNA damage enhanced by the attenuation of SLD5 delays cell cycle restoration in normal cells but not in cancer cells  PLoS One  2014  21;9(10):e110483  PubMed ID: 25334017
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