| User's Publication |
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11817
Suzuki T, Kohyama K, Moriyama K, Ozaki M, Hasegawa S, Ueno T, Saitoe M, Morio T, Hayashi M, Sakuma H.
Extracellular ADP augments microglial inflammasome and NF-κB activation via the P2Y12 receptor.
Eur. J. Immunol.
2020
50(2):205-219
PubMed ID: 31549730
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12025
Ogawa K, Yagi T, Guo T, Takeda K, Ohguchi H, Koyama H, Aotani D, Imaeda K, Kataoka H, Tanaka T.
Pemafibrate, a selective PPARα modulator, and fenofibrate suppress microglial activation through distinct PPARα and SIRT1-dependent pathways.
Biochem. Biophys. Res. Commun.
2020
PubMed ID: 32005522
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11351
Ni J, Wu Z, Stoka V, Meng J, Hayashi Y, Peters C, Qing H, Turk V, Nakanishi H.
Increased expression and altered subcellular distribution of cathepsin B in microglia induce cognitive impairment through oxidative stress and inflammatory response in mice.
Aging Cell
2019
PubMed ID: 30575263
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5292
Huntula S, Saegusa H, Wang X, Zong S, Tanabe T.
Involvement of N-type Ca2+ channel in microglial activation and its implications to aging-induced exaggerated cytokine response.
Cell Calcium
2019
82:102059
PubMed ID: 31377554
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5306
Saputra WD, Aoyama N, Komai M, Shirakawa H4,.
Menaquinone-4 Suppresses Lipopolysaccharide-Induced Inflammation in MG6 Mouse Microglia-Derived Cells by Inhibiting the NF-κB Signaling Pathway.
Int J Mol Sci
2019
20(9). pii: E2317
PubMed ID: 31083359
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5308
Inoue T, Yamakage H, Tanaka M, Kusakabe T, Shimatsu A, Satoh-Asahara N.
Oxytocin Suppresses Inflammatory Responses Induced by Lipopolysaccharide through Inhibition of the eIF-2-ATF4 Pathway in Mouse Microglia.
Cells
2019
8(6):527
PubMed ID: 31159306
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5316
Youssef M, Ibrahim A, Akashi K, Hossain MS.
PUFA-Plasmalogens Attenuate the LPS-Induced Nitric Oxide Production by Inhibiting the NF-kB, p38 MAPK and JNK Pathways in Microglial Cells.
Neuroscience
2019
15;397:18-30
PubMed ID: 30496826
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5319
Fujikura M1, Iwahara N, Hisahara S, Kawamata J, Matsumura A, Yokokawa K, Saito T, Manabe T, Matsushita T, Suzuki S, Shimohama S.
CD14 and Toll-Like Receptor 4 Promote Fibrillar Aβ42 Uptake by Microglia Through A Clathrin-Mediated Pathway.
J Alzheimers Dis
2019
68(1):323-337
PubMed ID: 30775984
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5320
Palikhe S, Ohashi W, Sakamoto T, Hattori K, Kawakami M, Andoh T, Yamazaki H, Hattori Y.
Regulatory Role of GRK2 in the TLR Signaling-Mediated iNOS Induction Pathway in Microglial Cells.
Front Pharmacol
2019
10:59
PubMed ID: 30778300
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11614
Wang X, Saegusa H, Huntula S, Tanabe T.
Blockade of microglial Cav1.2 Ca2+ channel exacerbates the symptoms in a Parkinson's disease model.
Sci Rep
2019
PubMed ID: 31235768
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11777
Ni J, Wu Z, Meng J, Saito T, Saido TC, Qing H, Nakanishi H.
An impaired intrinsic microglial clock system induces neuroinflammatory alterations in the early stage of amyloid precursor protein knock-in mouse brain.
J Neuroinflammation
2019
16(1):173
PubMed ID: 31470863
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10687
Yasuhiro Nakagawa, Yuto Yano, Jeonggyu Lee, Yasutaka Anraku, Makoto Nakakido Makoto Nakakido, Kouhei Tsumoto, Horacio Cabral, and Mitsuhiro Ebara
Apoptotic Cell-Inspired Polymeric Particles for Controlling Microglial Inflammation toward Neurodegenerative Disease Treatment
ACS Biomater Sci Eng
2019
5:5705–5713
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10710
Kidana K, Tatebe T, Ito K, Hara N, Kakita A, Saito T, Takatori S, Ouchi Y, Ikeuchi T, Makino M, Saido TC, Akishita M, Iwatsubo T, Hori Y, Tomita T.
Loss of kallikrein-related peptidase 7 exacerbates amyloid pathology in Alzheimer's disease model mice.
EMBO Mol Med
2018
PubMed ID: 29311134
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10775
Kawakami M, Hattori M, Ohashi W, Fujimori T, Hattori K, Takebe M, Tomita K, Yokoo H, Matsuda N, Yamazaki M, Hattori Y.
Role of G protein-coupled receptor kinase 2 in oxidative and nitrosative stress-related neurohistopathological changes in a mouse model of sepsis-associated encephalopathy.
J. Neurochem.
2018
145(6):474-488
PubMed ID: 29500815
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11056
Meng J, Ni J, Wu Z, Jiang M, Zhu A, Qing H, Nakanishi H.
The Critical Role of IL-10 in the Anti-neuroinflammatory and Anti-oxidative Effects of Rheum tanguticum on Activated Microglia
Oxid Med Cell Longev
2018
2018:1083596
PubMed ID: 29854069
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4423
Effects of antiepileptic drugs on microglial properties
Epilepsy & Seizure
2018
10, 22-32
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4293
Serizawa K, Tomizawa-Shinohara H, Magi M, Yogo K, Matsumoto Y.
Anti-IL-6 receptor antibody improves pain symptoms in mice with experimental autoimmune encephalomyelitis.
J. Neuroimmunol.
2018
PubMed ID: 29685293
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4294
Shimamura M, Nakagami H, Shimizu H, Mukai H, Watanabe R, Okuzono T, Kawano T, Ikeda Y, Hayashi H, Yoshida S, Ju N, Mochizuki H, Morishita R.
Development of a novel RANKL-based peptide, microglial healing peptide1-AcN (MHP1-AcN), for treatment of ischemic stroke.
Sci Rep
2018
PubMed ID: 30538259
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4295
Shimamura M, Nakagami H, Shimizu H, Wakayama K, Kawano T, Ikeda Y, Hayashi H, Yoshida S, Mochizuki H, Morishita R.
Therapeutic Effects of Systemic Administration of the Novel RANKL-Modified Peptide, MHP1, for Ischemic Stroke in Mice.
Biomed Res Int
2018
PubMed ID: 30151382
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7030
Wu Z, Ni J, Liu Y, Teeling JL, Takayama F, Collcutt A, Ibbett P, Nakanishi H.
Cathepsin B plays a critical role in inducing Alzheimer's disease-like phenotypes following chronic systemic exposure to lipopolysaccharide from Porphyromonas gingivalis in mice.
Brain Behav. Immun.
2017
65:350-361
PubMed ID: 28610747
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10102
Mahmoud ME, Fereig R, Nishikawa Y.
Involvement of Host Defense Mechanisms against Toxoplasma gondii Infection in Anhedonic and Despair-Like Behaviors in Mice.
Infect. Immun.
2017
85:
PubMed ID: 28138019
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10138
Inoue T, Tanaka M, Masuda S, Ohue-Kitano R, Yamakage H, Muranaka K, Wada H, Kusakabe T, Shimatsu A, Hasegawa K, Satoh-Asahara N.
Omega-3 polyunsaturated fatty acids suppress the inflammatory responses of lipopolysaccharide-stimulated mouse microglia by activating SIRT1 pathways.
Biochim. Biophys. Acta
2017
1862:552-560
PubMed ID: 28254441
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10527
Liu Y, Wu Z, Nakanishi Y, Ni J, Hayashi Y, Takayama F, Zhou Y, Kadawaki T, Nakanishi H.
Infection of microglia with Porphyromonas gingivalis promotes cell migration and an inflammatory response through the gingipain-mediated activation of protease-activated receptor-2 in mice.
Sci Rep
2017
7:11759
PubMed ID: 28924232
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5311
Koshiguchi M, Komazaki H, Hirai S, Egashira Y.
Ferulic acid suppresses expression of tryptophan metabolic key enzyme indoleamine 2, 3-dioxygenase via NFκB and p38 MAPK in lipopolysaccharide-stimulated microglial cells.
Biosci Biotechnol Biochem
2017
81(5):966-971
PubMed ID: 28077028
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9595
Hossain MS, Mineno K, Katafuchi T.
Neuronal Orphan G-Protein Coupled Receptor Proteins Mediate Plasmalogens-Induced Activation of ERK and Akt Signaling.
PLoS ONE
2016
11:e0150846
PubMed ID: 26934370
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9766
Takayama F, Hayashi Y, Wu Z, Liu Y, Nakanishi H.
Diurnal dynamic behavior of microglia in response to infected bacteria through the UDP-P2Y6 receptor system.
Sci Rep
2016
6:30006
PubMed ID: 27445174
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9970
Kurinami H, Shimamura M, Nakagami H, Shimizu H, Koriyama H, Kawano T, Wakayama K, Mochizuki H, Rakugi H, Morishita R.
A Novel Therapeutic Peptide as a Partial Agonist of RANKL in Ischemic Stroke.
Sci Rep
2016
6:38062
PubMed ID: 27897273
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7104
Hosain MZ, Mori T, Kishimura A, Katayama Y.
Synergy between phenotypic modulation and ROS neutralization in reduction of inflammatory response of hypoxic microglia by using phosphatidylserine and antioxidant containing liposomes.
J Biomater Sci Polym Ed
2015
27:290-302
PubMed ID: 26689775
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7218
Ni J, Wu Z, Peterts C, Yamamoto K, Qing H, Nakanishi H.
The Critical Role of Proteolytic Relay through Cathepsins B and E in the Phenotypic Change of Microglia/Macrophage.
J. Neurosci.
2015
35:12488-501
PubMed ID: 26354916
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7247
Takenouchi T, Tsukimoto M, Iwamaru Y, Sugama S, Sekiyama K, Sato M, Kojima S, Hashimoto M, Kitani H.
Extracellular ATP induces unconventional release of glyceraldehyde-3-phosphate dehydrogenase from microglial cells.
Immunol. Lett.
2015
167:116-24
PubMed ID: 26277554
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7369
Segawa S, Tatsumi N, Ohishi A, Nishida K, Nagasawa K.
Characterization of zinc uptake by mouse primary cultured astrocytes and microglia.
Metallomics
2015
7:1067-77
PubMed ID: 25924210
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5303
Yu Z, Ono C, Aiba S, Kikuchi Y, Sora I, Matsuoka H, Tomita H.
Therapeutic concentration of lithium stimulates complement C3 production in dendritic cells and microglia via GSK-3 inhibition.
Glia
2015
63(2):257-70
PubMed ID: 25179772
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5314
Bahrini I, Song JH, Diez D, Hanayama R.
Neuronal exosomes facilitate synaptic pruning by up-regulating complement factors in microglia.
Sci Rep
2015
5:7989
PubMed ID: 25612542
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5313
Ishisaka A, Mukai R, Terao J, Shibata N, Kawai Y.
Specific localization of quercetin-3-O-glucuronide in human brain.
Arch Biochem Biophys
2014
557:11-7
PubMed ID: 24893148
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5317
Jin Y, Sato K, Tobo A, Mogi C, Tobo M, Murata N, Ishii S, Im DS, Okajima F.
Inhibition of interleukin-1β production by extracellular acidification through the TDAG8/cAMP pathway in mouse microglia.
J Neurochem
2014
129(4):683-95
PubMed ID: 24447140
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5321
Kotake M, Sato K, Mogi C, Tobo M, Aoki H, Ishizuka T, Sunaga N, Imai H, Kaira K, Hisada T, Yamada M, Okajima F.
Acidic pH increases cGMP accumulation through the OGR1/phospholipase C/Ca(2+)/neuronal NOS pathway in N1E-115 neuronal cells.
Cell Signal
2014
26(11):2326-32
PubMed ID: 25025574
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5304
Liu Y, Wu Z, Zhang X, Ni J, Yu W, Zhou Y, Nakanishi H.
Leptomeningeal cells transduce peripheral macrophages inflammatory signal to microglia in reponse to Porphyromonas gingivalis LPS.
Mediators Inflamm
2013
2013:407562
PubMed ID: 24363500
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5305
Wu Z, Zhu A, Takayama F, Okada R, Liu Y, Harada Y, Wu S, Nakanishi H.
Brazilian green propolis suppresses the hypoxia-induced neuroinflammatory responses by inhibiting NF-κB activation in microglia.
Oxid Med Cell Longev
2013
2013:906726
PubMed ID: 23983903
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7591
Kitajima H, Komizu Y, Ueoka R.
Hybrid liposomes inhibit growth and invasion of human osteosarcoma cells leading to apoptosis.
Bioorg. Med. Chem. Lett.
2012
22:1784-7
PubMed ID: 22260774
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7594
Yanagitai M, Itoh S, Kitagawa T, Takenouchi T, Kitani H, Satoh T.
Carnosic acid, a pro-electrophilic compound, inhibits LPS-induced activation of microglia.
Biochem. Biophys. Res. Commun.
2012
418:22-6
PubMed ID: 22214931
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5312
Mukai R, Kawabata K, Otsuka S, Ishisaka A, Kawai Y, Ji ZS, Tsuboi H, Terao J.
Effect of quercetin and its glucuronide metabolite upon 6-hydroxydopamine-induced oxidative damage in Neuro-2a cells.
Free Radic Res
2012
46(8):1019-28
PubMed ID: 22404304
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7884
Takenouchi T, Iwamaru Y, Sugama S, Tsukimoto M, Fujita M, Sekigawa A, Sekiyama K, Sato M, Kojima S, Conti B, Hashimoto M, Kitani H.
The activation of P2X7 receptor induces cathepsin D-dependent production of a 20-kDa form of IL-1β under acidic extracellular pH in LPS-primed microglial cells.
J. Neurochem.
2011
117:712-23
PubMed ID: 21395581
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10347
Denehy TR, Choe JY, Gregori CA, Breen JL.
Modified Le Fort partial colpocleisis with Kelly urethral plication and posterior colpoperineoplasty in the medically compromised elderly: a comparison with vaginal hysterectomy, anterior colporrhaphy, and posterior colpoperineoplasty.
Am. J. Obstet. Gynecol.
1995
173:1697-701
PubMed ID: 8610747
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