CELL SEARCH SYSTEM -CELL BANK- (RIKEN BRC) [RCB2280 : HCE-T]

9981 Araki-Sasaki K, Aizawa S, Hiramoto M, Nakamura M, Iwase O, Nakata K, Sasaki Y, Mano T, Handa H, Tano Y. Substance P-induced cadherin expression and its signal transduction in a cloned human corneal epithelial cell line. J Cell Physiol 2000 182(2):189-95 PubMed ID: 10623882 DOI: 10.1002/(SICI)1097-4652(200002)182:2<189::AID-JCP7>3.0.CO;2-9

9980 Saarinen-Savolainen P, Järvinen T, Araki-Sasaki K, Watanabe H, Urtti A. Author information Evaluation of cytotoxicity of various ophthalmic drugs, eye drop excipients and cyclodextrins in an immortalized human corneal epithelial cell line. Pharm Res 1998 15(8):1275-80 PubMed ID: 9706061 DOI: 10.1023/a:1011956327987

2263 Araki-Sasaki K, Ohashi Y, Sasabe T, Hayashi K, Watanabe H, Tano Y, Handa H An SV40-immortalized human corneal epithelial cell line and its characterization. Invest Ophthalmol Vis Sci 1995 36:614-21 PubMed ID: 7534282

2262 Zhang Y, Araki-Sasaki K, Handa H, Akhtar, R A Effect of carbachol on phospholipase C-mediated phosphatidylinositol 4,5-bisphosphate hydrolysis, and its modulation by isoproterenol in rabbit corneal epithelial cells. Curr Eye Res 1995 14:563-71 PubMed ID: 7587302 DOI: 10.3109/02713689508998403

2261 Araki K, Ohashi Y, Sasabe T, Kinoshita S, Hayashi K, Yang, X Z, Hosaka Y, Aizawa S, Handa H Immortalization of rabbit corneal epithelial cells by a recombinant SV40-adenovirus vector. Invest Ophthalmol Vis Sci 1993 34:2665-71 PubMed ID: 7688358

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21704 Zeng Z, Yoshida Y, Wang D, Fujii Y, Shen M, Mimura T, Tanaka Y. Inflammatory Cytokines and Chemokines Are Synergistically Induced in a ROS-Dependent Manner by a Co-Culture of Corneal Epithelial Cells and Neutrophil-like Cells in the Presence of Particulate Matter. Antioxidants (Basel) 2024 13(4) PubMed ID: 38671915 DOI: 10.3390/antiox13040467

21742 Lochenie C, Duncan S, Zhou Y, Fingerhut L, Kiang A, Benson S, Jiang G, Liu X, Mills B, Vendrell M. Photosensitizer-Amplified Antimicrobial Materials for Broad-spectrum Ablation of Resistant Pathogens in Ocular Infections. Adv Mater 2024 e2404107 PubMed ID: 38762778 DOI: 10.1002/adma.202404107

21813 Kleinman D, Iqbal S, Ghosh AK, Ogle SD, Kaja S, Mitchnick M, Hakkarainen JJ. PLL-g-PEG Polymer Inhibits Antibody-Drug Conjugate Uptake into Human Corneal Epithelial Cells In Vitro. J Ocul Pharmacol Ther 2024 PubMed ID: 38935528 DOI: 10.1089/jop.2024.0019

22101 Abbasi M, Amini M, Moustardas P, Gutsmiedl Q, Javidjam D, Suiwal S, Seitz B, Fries FN, Dashti A, Rautavaara Y, Stachon T, Szentmáry N, Lagali N. Effects of miR-204-5p modulation on PAX6 regulation and corneal inflammation. Sci Rep 2024 14(1):26436 PubMed ID: 39488562 DOI: 10.1038/s41598-024-76654-w

22120 Wasilewicz A, Areesanan A, Kirchweger B, Nicolay S, Waltenberger E, Beniddir MA, Gründemann C, Rollinger JM, Grienke U. Combining the Strengths of MS and NMR in Biochemometrics: A Case Study on Buddleja officinalis. J Nat Prod 2024 PubMed ID: 39503999 DOI: 10.1021/acs.jnatprod.4c00847

22128 Areesanan A, Wasilewicz A, Kirchweger B, Nicolay S, Zimmermann-Klemd A, Grienke U, Rollinger JM, Gründemann C. Pharmacological in vitro profiling of Buddleja officinalis flower extracts in the context of dry eye disease. Biomed Pharmacother 2024 181:117685 PubMed ID: 39541792 DOI: 10.1016/j.biopha.2024.117685

17736 Ong HS, Riau AK, Yam GH, Yusoff NZBM, Han EJY, Goh TW, Lai RC, Lim SK, Mehta JS. Mesenchymal Stem Cell Exosomes as Immunomodulatory Therapy for Corneal Scarring Int J Mol Sci 2023 24(8):7456 PubMed ID: 37108619 DOI: 10.3390/ijms24087456

17782 Ban Y, Yoshida Y, Aziza Y, Kinoshita S, Sotozono C. Strengthening of the barrier function in human telomerase reverse transcription (hTERT) immortalized corneal and conjunctival epithelium by double-stranded RNA Exp Eye Res 2023 227:109357 PubMed ID: 36572167 DOI: 10.1016/j.exer.2022.109357

19536 Wang J, Shang KT, Ma QH, Dong ZY, Chen YH, Yao YF. Herpes Simplex Virus Type 1 Infection Induces the Formation of Tunneling Nanotubes Microorganisms 2023 11(8):1916 PubMed ID: 37630476 DOI: 10.3390/microorganisms11081916

19579 Hao R, Hu S, Zhang H, Chen X, Yu Z, Ren J, Guo H, Yang H. Mechanical stimulation on a microfluidic device to highly enhance small extracellular vesicle secretion of mesenchymal stem cells Mater Today Bio 2023 18:100527 PubMed ID: 36619203 DOI: 10.1016/j.mtbio.2022.100527

19618 Anitua E, de la Fuente M, Sánchez-Ávila RM, de la Sen-Corcuera B, Merayo-Lloves J, Muruzábal F. Beneficial Effects of Plasma Rich in Growth Factors (PRGF) Versus Autologous Serum and Topical Insulin in Ocular Surface Cells Curr Eye Res 2023 48(5):456-464 PubMed ID: 36695530 DOI: 10.1080/02713683.2023.2173237

19623 Chen K, Jin L, Wen Y, Yang Q, Li X, Zhang L, Wang L, Xia Y, Chen Z, Xie C, Tong J, Shen Y. Blue light impairs cornea and corneal wound healing by downregulating VCAM1 partly iScience 2023 26(12):108448 PubMed ID: 38034364 DOI: 10.1016/j.isci.2023.108448

19660 Ryosuke Fukuda, Nargis Mahmuda, Sawangrat Kasirawat, Ryo Kawakami, Rumina Shima, Yu Mizukami, Shiori Shibukawa, Yuki Tada, Fumitake Kawanishi, Masatsune Ogura, Kota Matsuki, Yoshinori Nagai, Eri Nakano, Kenji Suda, Akitaka Tsujikawa, Tatsuya Murakami High‐Density Lipoprotein Engineering for Eye‐Drop Treatment of Age‐Related Macular Degeneration Advanced Therapeutics 2023 6 DOI: 10.1002/adtp.202300186

19726 Chai N, Stachon T, Nastaranpour M, Li Z, Seitz B, Ulrich M, Langenbucher A, Szentmáry N. Assessment of Rose Bengal Photodynamic Therapy on Viability and Proliferation of Human Keratolimbal Epithelial and Stromal Cells In Vitro Klin Monbl Augenheilkd 2023 Jun 19 PubMed ID: 36808578 DOI: 10.1055/a-2038-8899

21275 Kang WS, Kim E, Choi H, Lee KH, Kim KJ, Lim D, Choi SY, Kim Y, Son SA, Kim JS, Kim S. Therapeutic Potential of Peucedanum japonicum Thunb. and Its Active Components in a Delayed Corneal Wound Healing Model Following Blue Light Irradiation-Induced Oxidative Stress. Antioxidants (Basel) 2023 12(6) PubMed ID: 37371901 DOI: 10.3390/antiox12061171

21302 Iwasaki T, Uchiyama R, Nosaka K. New Candidate Preservative in Ophthalmic Solution Instead of Benzalkonium Chloride: 1,3-Didecyl-2-methyl Imidazolium Chloride. Chem Pharm Bull (Tokyo) 2023 71(7):552-557 PubMed ID: 37394604 DOI: 10.1248/cpb.c23-00115

21417 Ghosh S, Humera Khathun AH, Athulya GS, Vignesh P, Mathan L, Mudaraddi N, Narendran S, Lalitha P, Venkatesh Prajna N. Host cell-type and pathogen-specific immunomodulatory functions of macrophage migration inhibitory factor (MIF) in infectious keratitis. Exp Eye Res 2023 109669 PubMed ID: 37774962 DOI: 10.1016/j.exer.2023.109669

21457 Abdalkader RK, Fujita T. Corneal epithelium models for safety assessment in drug development: Present and future directions. Exp Eye Res 2023 237:109697 PubMed ID: 37890755 DOI: 10.1016/j.exer.2023.109697

21463 Areesanan A, Nicolay S, Keller M, Zimmermann-Klemd AM, Potterat O, Gründemann C. Potential benefits of Malva sylvestris in dry-eye disease pathology in vitro based on antioxidant, wound-healing and anti-inflammatory properties. Biomed Pharmacother 2023 168:115782 PubMed ID: 37924786 DOI: 10.1016/j.biopha.2023.115782

21535 Chai N, Stachon T, Berger T, Li Z, Seitz B, Langenbucher A, Szentmáry N. Human corneal epithelial cell and fibroblast migration and growth factor secretion after rose bengal photodynamic therapy (RB-PDT) and the effect of conditioned medium. PLoS One 2023 18(12):e0296022 PubMed ID: 38150488 DOI: 10.1371/journal.pone.0296022

21557 Malakouti-Nejad M, Monti D, Burgalassi S, Bardania H, Elahi E, Morshedi D. A comparison between the effects of two liposome-encapsulated bevacizumab formulations on ocular neovascularization inhibition. Colloids Surf B Biointerfaces 2023 234:113708 PubMed ID: 38141384 DOI: 10.1016/j.colsurfb.2023.113708

17539 Otsu W, Yako T, Sugisawa E, Nakamura S, Tsusaki H, Umigai N, Shimazawa M, Hara H. Crocetin protects against mitochondrial damage induced by UV-A irradiation in corneal epithelial cell line HCE-T cells J Pharmacol Sci 2022 150(4):279-288 PubMed ID: 36344051 DOI: 10.1016/j.jphs.2022.10.005

17614 Abbate I, Zappulla C, Santonocito M, Viola S, La Rosa LR, De Pasquale G, Caviola E, Meloni M, Curatolo MC, Mazzone MG. Preclinical study of a new matrix to help the ocular surface in dry eye disease Exp Eye Res 2022 222:109168 PubMed ID: 35777472 DOI: 10.1016/j.exer.2022.109168

17632 Yihui Song, Sheng Hua, Sepidar Sayyar, Zhi Chen, Johnson Chung, Xiao Liu, Zhilian Yue, Cameron Angus, Benjamin Filippi, Stephen Beirne, Gordon Wallace, Gerard Sutton, Jingjing You Corneal bioprinting using a high concentration pure collagen I transparent bioink Corneal bioprinting using a high concentration pure collagen I transparent bioink 2022 28:e00235 DOI: 10.1016/j.bprint.2022.e00235

18228 Jactty Chew, Tommy Tong, Mun Lok Chua, Mohammad Ridwane Mungroo, Yi Xing Yap, Misni Misran, Lai Ti Gew The Antibacterial Activity of Zinc Oxide Nanoparticle-Loaded Soft Contact Lens Current Chemical Biology 2022 16:138-144 DOI: 10.2174/2212796816666220419121948

15508 Yu Z, Hao R, Du J, Wu X, Chen X, Zhang Y, Li W, Gu Z, Yang H. A human cornea-on-a-chip for the study of epithelial wound healing by extracellular vesicles iScience 2022 25(5):104200 PubMed ID: 35479406 DOI: 10.1016/j.isci.2022.104200

20515 Arunachalam D, Ramanathan SM, Menon A, Madhav L, Ramaswamy G, Namperumalsamy VP, Prajna L, Kuppamuthu D. Expression of immune response genes in human corneal epithelial cells interacting with Aspergillus flavus conidia. BMC Genomics 2022 23(1):5 PubMed ID: 34983375 DOI: 10.1186/s12864-021-08218-5

20586 Schwab R, Reichl S. Dexamethasone-loaded keratin films for ocular surface reconstruction. J Mater Sci Mater Med 2022 33(3):29 PubMed ID: 35244790 DOI: 10.1007/s10856-021-06638-z

16666 Abdalkader R, Kamei KI. An efficient simplified method for the generation of corneal epithelial cells from human pluripotent stem cells Hum Cell 2022 35(4):1016-1029 PubMed ID: 35553384 DOI: 10.1007/s13577-022-00713-5

16695 Kanae Moriya, Hisanori Shimizu, Daisuke Kamei, Satoko Handa, Tadanori Sasaki, Yasuhisa Kato Evaluation of corneal damage caused by the anticancer drug S-1 in human corneal epithelial cells The Showa University Journal of Medical Sciences 2022 34:27-32 DOI: 10.15369/sujms.34.27

20797 Cai J, Jacob S, Kurupi R, Dalton KM, Coon C, Greninger P, Egan RK, Stein GT, Murchie E, McClanaghan J, Adachi Y, Hirade K, Dozmorov M, Glod J, Boikos SA, Ebi H, Hao H, Caponigro G, Benes CH, Faber AC. High-risk neuroblastoma with NF1 loss of function is targetable using SHP2 inhibition. Cell Rep 2022 40(4):111095 PubMed ID: 35905710 DOI: 10.1016/j.celrep.2022.111095

20929 Anitua E, Fuente M, Merayo-Lloves J, Muruzabal F. Optimization of a Plasma Rich in Growth Factors Membrane for the Treatment of Inflammatory Ocular Diseases. Bioengineering (Basel) 2022 9(10) PubMed ID: 36290475 DOI: 10.3390/bioengineering9100508

13379 Wu C, Or PW, Chong JIT, Pathirage Don IKK, Lee CHC, Wu K, Yu M, Lam DCC, Yang Y. Extended Delivery of Pirfenidone with Novel, Soft Contact Lenses In Vitro and In Vivo. J Ocul Pharmacol Ther 2021 37(2):75-83. PubMed ID: 33297836 DOI: 10.1089/jop.2020.0058

13392 Lai YH, Lee PY, Lu CY, Liu YR, Wang SC, Liu CC, Chang YC, Chen YH, Su CC, Li CY, Liu PL. Thrombospondin 1-induced exosomal proteins attenuate hypoxia-induced paraptosis in corneal epithelial cells and promote wound healing. FASEB J 2021 PubMed ID: 33341997 DOI: 10.1096/fj.202001106RRR

20039 Kaluzhny Y, Klausner M. In vitro reconstructed 3D corneal tissue models for ocular toxicology and ophthalmic drug development. 2021 PubMed ID: 33544359 DOI: 10.1007/s11626-020-00533-7

20091 Xu M, Sivak JG, McCanna DJ. Neutralization of the eye and skin irritant benzalkonium chloride using UVC radiation. Cutan Ocul Toxicol 2021 1-7 PubMed ID: 33771058 DOI: 10.1080/15569527.2021.1902339

20140 Furuya K, Wu T, Orimoto A, Sugano E, Tomita H, Kiyono T, Kurose T, Takai Y, Fukuda T. The transcriptome of wild-type and immortalized corneal epithelial cells. Sci Data 2021 8(1):126 PubMed ID: 33963195 DOI: 10.1038/s41597-021-00908-9

14367 Dalton KM, Krytska K, Lochmann TL, Sano R, Casey C, D'Aulerio A, Khan QA, Stein Crowther G, Coon C, Cai J, Jacob S, Kurupi R, Hu B, Dozmorov M, Greninger P, Souers AJ, Benes CH, Mossé YP, Faber AC. Venetoclax-based rational combinations are effective in models of MYCN-amplified neuroblastoma Mol Cancer Ther 2021 PubMed ID: 34088831 DOI: 10.1158/1535-7163.MCT-20-0710

14518 Bíró T, Bocsik A, Jurišić Dukovski B, Gróf I, Lovrić J, Csóka I, Deli MA, Aigner Z. New Approach in Ocular Drug Delivery: In vitro and ex vivo Investigation of Cyclodextrin-Containing, Mucoadhesive Eye Drop Formulations Drug Des Devel Ther 2021 15:351-360 PubMed ID: 33568896 DOI: 10.2147/DDDT.S264745

14702 Račić A, Čalija B, Milić J, Dukovski BJ, Lovrić J, Dobričić V, Micov A, Vuković M, Stepanović-Petrović R, Krajišnik D. Formulation of olopatadine hydrochloride viscous eye drops - physicochemical, biopharmaceutical and efficacy assessment using in vitro and in vivo approaches Eur J Pharm Sci 2021 105906 PubMed ID: 34118409 DOI: 10.1016/j.ejps.2021.105906

15098 Agnė Žiniauskaitė, Vytautas Cėpla, Tadas Jelinskas, Romuald Eimont, Artūras Ulčinas, Rūta Aldonytė, Ramūnas Valiokas, Giedrius Kalesnykas, Jenni J. Hakkarainen Introducing an Efficient In Vitro Cornea Mimetic Model for Testing Drug Permeability Sci 2021 3:30 DOI: 10.3390/sci3030030

20266 Abdalkader R, Chaleckis R, Wheelock CE, Kamei KI. Spatiotemporal determination of metabolite activities in the corneal epithelium on a chip. Exp Eye Res 2021 209:108646 PubMed ID: 34102209 DOI: 10.1016/j.exer.2021.108646

20368 Lin TL, Cheng C, Zeng WT, Duan F, Pei YH, Liu XP, Shang F, Wu KL. Anti-viral activity of Staphylococcus aureus lysates against herpes simplex virus type-I infection: an in vitro and in vivo study. Int J Ophthalmol 2021 14(10):1463-1472 PubMed ID: 34667721 DOI: 10.18240/ijo.2021.10.01

15676 Ghosh AK, Thapa R, Hariani HN, Volyanyuk M, Ogle SD, Orloff KA, Ankireddy S, Lai K, Žiniauskaitė A, Stubbs EB Jr, Kalesnykas G, Hakkarainen JJ, Langert KA, Kaja S. Poly(lactic-co-glycolic acid) Nanoparticles Encapsulating the Prenylated Flavonoid, Xanthohumol, Protect Corneal Epithelial Cells from Dry Eye Disease-Associated Oxidative Stress Pharmaceutics 2021 13(9):1362 PubMed ID: 34575438 DOI: 10.3390/pharmaceutics13091362

15678 Magny R, Regazzetti A, Kessal K, Baudouin C, Mélik-Parsadaniantz S, Laprévote O, Brignole-Baudouin F, Auzeil N, Roulland E. Deepening of lipidome annotation by associating cross-metathesis reaction with mass spectrometry: application to an in vitro model of corneal toxicity Anal Bioanal Chem 2021 413(19):4825-4836 PubMed ID: 34125263 DOI: 10.1007/s00216-021-03438-w

20447 Otsu W, Ishida K, Chinen N, Nakamura S, Shimazawa M, Tsusaki H, Hara H. Cigarette smoke extract and heated tobacco products promote ferritin cleavage and iron accumulation in human corneal epithelial cells. Sci Rep 2021 11(1):18555 PubMed ID: 34535730 DOI: 10.1038/s41598-021-97956-3

20505 Goto R, Yamada S, Otake H, Nakazawa Y, Oka M, Yamamoto N, Sasaki H, Nagai N. Instillation of Ophthalmic Formulation Containing Nilvadipine Nanocrystals Attenuates Lens Opacification in Shumiya Cataract Rats. Pharmaceutics 2021 13(12) PubMed ID: 34959281 DOI: 10.3390/pharmaceutics13121999

14734 Arunachalam D, Namperumalsamy VP, Prajna L, Kuppamuthu D. Human Corneal Epithelial Cells Internalize Aspergillus flavus Spores by Actin-Mediated Endocytosis Infect Immun 2021 89(6):e00794-20 PubMed ID: 33753415 DOI: 10.1128/IAI.00794-20

11687 Mungroo MR, Tong T, Khan NA, Anuar TS, Maciver SK, Siddiqui R. Development of anti-acanthamoebic approaches Int Microbiol 2021 24(3):363-371 PubMed ID: 33754231 DOI: 10.1007/s10123-021-00171-3

16667 Wu C, Or PW, Chong JIT, K Pathirage Don IK, Lee CHC, Wu K, Yu M, Lam DCC, Yang Y. Controllable release of pirfenidone by polyvinyl alcohol film embedded soft contact lenses in vitro and in vivo Drug Deliv 2021 28(1):634-641 PubMed ID: 33779455 DOI: 10.1080/10717544.2021.1895911

16669 Banshoya K, Fujita C, Hokimoto Y, Ohnishi M, Inoue A, Tanaka T, Kaneo Y. Amphotericin B nanohydrogel ocular formulation using alkyl glyceryl hyaluronic acid: Formulation, characterization, and in vitro evaluation Int J Pharm 2021 610:121061 PubMed ID: 34481008 DOI: 10.1016/j.ijpharm.2021.121061

16671 Yamashiro C, Tokuda K, Kobayashi Y, Higashijima F, Yoshimoto T, Ota M, Ogata T, Ashimori A, Kobayashi M, Hatano M, Uchi SH, Wakuta M, Teranishi S, Kimura K. Benzalkonium chloride-induced myofibroblastic transdifferentiation of Tenon's capsule fibroblasts is inhibited by coculture with corneal epithelial cells or by interleukin-10 Sci Rep 2021 11(1):16096 PubMed ID: 34373467 DOI: 10.1038/s41598-021-94852-8

16672 Kang WS, Choi H, Lee KH, Kim E, Kim KJ, Kim JS, Na CS, Kim S. Peucedanum japonicum Thunberg and Its Active Components Mitigate Oxidative Stress, Inflammation and Apoptosis after Urban Particulate Matter-Induced Ocular Surface Damage Antioxidants (Basel) 2021 10(11):1717. PubMed ID: 34829588 DOI: 10.3390/antiox10111717

16673 Bianchini G, Tomassetti M, Lillini S, Sirico A, Bovolenta S, Za L, Liberati C, Novelli R, Aramini A. Discovery of Novel TRPM8 Blockers Suitable for the Treatment of Somatic and Ocular Painful Conditions: A Journey through p Ka and LogD Modulation J Med Chem 2021 64(22):16820-16837 PubMed ID: 34762442 DOI: 10.1021/acs.jmedchem.1c01647

16789 Wang S, Hou F, Yao YF, Pan D. Efficient establishment of reactivatable latency by an acyclovir-resistant herpes simplex virus 1 thymidine kinase substitution mutant with reduced neuronal replication Virology 2021 556:140-148 PubMed ID: 33631413 DOI: 10.1016/j.virol.2021.01.016

6967 Seino S1,, Matsuoka R, Masuda Y, Kunou M, Okada Y, Saika S. Topical hyaluronan alone promotes corneal epithelial cell migration whereas combination with benzalkonium chloride impairs epithelial wound healing. Cutan Ocul Toxicol 2020 39(1):13-20 PubMed ID: 31588814 DOI: 10.1080/15569527.2019.1673402

11893 Vitoux MA, Kessal K, Melik Parsadaniantz S, Claret M, Guerin C, Baudouin C, Brignole-Baudouin F, Réaux-Le Goazigo A. Benzalkonium chloride-induced direct and indirect toxicity on corneal epithelial and trigeminal neuronal cells: proinflammatory and apoptotic responses in vitro. Toxicol. Lett. 2020 PubMed ID: 31707104 DOI: 10.1016/j.toxlet.2019.10.014

11963 Jurišić Dukovski B, Juretić M, Bračko D, Randjelović D, Savić S, Crespo Moral M, Diebold Y, Filipović-Grčić J, Pepić I, Lovrić J. Functional ibuprofen-loaded cationic nanoemulsion: Development and optimization for dry eye disease treatment. Int J Pharm 2020 PubMed ID: 31870964 DOI: 10.1016/j.ijpharm.2019.118979

11983 Zeng W, Zhang Y, Duan F, Lin T, Liu X, Li D, Wu K. Lipopolysaccharide enhances human herpesvirus 1 replication and IL-6 release in epithelial cells. Microb. Pathog. 2020 PubMed ID: 31904451 DOI: 10.1016/j.micpath.2019.103961

11998 Rubelowski AK, Latta L, Katiyar P, Stachon T, Käsmann-Kellner B, Seitz B, Szentmáry N. HCE-T cell line lacks cornea-specific differentiation markers compared to primary limbal epithelial cells and differentiated corneal epithelium. Graefes Arch. Clin. Exp. Ophthalmol. 2020 PubMed ID: 31927639 DOI: 10.1007/s00417-019-04563-0

12024 Fu R, Guo H, Janga S, Choi M, Klinngam W, Edman MC, Hamm-Alvarez SF. Cathepsin S activation contributes to elevated CX3CL1 (fractalkine) levels in tears of a Sjögren's syndrome murine model. Sci Rep 2020 10(1):1455 PubMed ID: 31996771 DOI: 10.1038/s41598-020-58337-4

12145 Davood Kharaghani, Debarun Dutta, Kitty K. K. Ho, Ke-Qin Zhang, Wei Kai, Xuehong Ren, Mark D. P. Willcox & Ick Soo Kim Active loading graphite/hydroxyapatite into the stable hydroxyethyl cellulose scaffold nanofibers for artificial cornea application Original Research 2020 DOI: 10.1007/s10570-020-02999-w

12173 Pierre-Louis Destruel,Ni Zeng, Françoise Brignole-Baudouin,Sophie Douat, Johanne Seguin, Elodie Olivier, Melody Dutot, ,Patrice Rat, Sophie Dufaÿ, Amélie Dufaÿ-Wojcicki, Marc Maury, Nathalie Mignet, * andVincent Boudy, In Situ Gelling Ophthalmic Drug Delivery System for the Optimization of Diagnostic and Preoperative Mydriasis: In Vitro Drug Release, Cytotoxicity and Mydriasis Pharmacodynamics Pharmaceutics 2020 PubMed ID: 32326492 DOI: 10.3390/pharmaceutics12040360

12965 Kabashima K, Murakami A, Ebihara N. Effects of Benzalkonium Chloride and Preservative-Free Composition on the Corneal Epithelium Cells. J Ocul Pharmacol Ther 2020 PubMed ID: 32552267 DOI: 10.1089/jop.2019.0165

12993 Matsuda Y, Machida M, Nakagami Y, Nakajima T, Azuma M. NFE2L2 activator RS9 protects against corneal epithelial cell damage in dry eye models. PLoS One 2020 PubMed ID: 32320433 DOI: 10.1371/journal.pone.0229421

13118 Kiss EL, Berkó S, Gácsi A, Kovács A, Katona G, Soós J, Csányi E, Gróf I, Harazin A, Deli MA, Balogh GT, Budai-Szűcs M. Development and Characterization of Potential Ocular Mucoadhesive Nano Lipid Carriers Using Full Factorial Design. Pharmaceutics 2020 PubMed ID: 32698334 DOI: 10.3390/pharmaceutics12070682

13271 Xu M, Sivak JG, McCanna DJ. Ocular toxicology: synergism of UV radiation and benzalkonium chloride. Cutan Ocul Toxicol 2020 PubMed ID: 33019823 DOI: 10.1080/15569527.2020.1833027

13318 Inaba K, Minami M, Yamaguchi M, Goto R, Otake H, Kotake T, Nagai N. Effects of the Ophthalmic Additive Mannitol on Antimicrobial Activity and Corneal Toxicity of Various Preservatives. Chem Pharm Bull (Tokyo) 2020 PubMed ID: 33132373 DOI: 10.1248/cpb.c20-00540

13339 Kashiwagi K, Iizuka Y. Effect and underlying mechanisms of airborne particulate matter 2.5 (PM2.5) on cultured human corneal epithelial cells. Sci Rep 2020 PubMed ID: 33177636 DOI: 10.1038/s41598-020-76651-9

13397 Frazer H, You J, Chen Z, Sayyar S, Liu X, Taylor A, Hodge C, Wallace G, Sutton G. Development of a Platelet Lysate-Based Printable, Transparent Biomaterial With Regenerative Potential for Epithelial Corneal Injuries. Transl Vis Sci Technol 2020 PubMed ID: 33442494 DOI: 10.1167/tvst.9.13.40

13425 Emi Ooe, Tomohiro Yako, Yoshiki Kuse, Tetsuya Sogon, Shinsuke Nakamura, Masamitsu Shimazawa, Hideaki Hara The protective effects of bilberry extract and its main constituents against blue light-emitting diode (LED) light-induced damage in human corneal epithelial cells Journal of Nutritional Food 2020 DOI: 10.20618/jhnfa.17.1_18

13569 He H, Liang M, Li L, Luo S, Fang X, He H, Xiao X, Wu H, Lin Z. PPAR-α Agonist Fenofibrate Suppressed the Formation of Ocular Surface Squamous Metaplasia Induced by Topical Benzalkonium Chloride Invest Ophthalmol Vis Sci 2020 61(3):54 PubMed ID: 32232349 DOI: 10.1167/iovs.61.3.54

13617 Abdalkader R, Kamei KI. Multi-corneal barrier-on-a-chip to recapitulate eye blinking shear stress forces Lab Chip 2020 20(8):1410-1417 PubMed ID: 32202263 DOI: 10.1039/c9lc01256g

13848 Kyung-A Kim, Chung Hyun Lee, Tae Kyeom Kang, Sung Jae Yang, Chang Yong Lee, Wook-Bin Lee & Sang Hoon Jung Effect of persimmon leaves (Diospyros kaki) on goblet cell density and inflammation in experimental dry eye model Applied Biological Chemistry 2020 63 DOI: 10.1186/s13765-020-00529-7

13904 Xu LJ, Rong SS, Xu YS, Zheng LB, Qiu WY, Zhang X, Jiang LJ, Duan RP, Tian T, Yao YF. Anti-fibrosis potential of pirarubicin via inducing apoptotic and autophagic cell death in rabbit conjunctiva Exp Eye Res 2020 200:108215 PubMed ID: 32896532 DOI: 10.1016/j.exer.2020.108215

13928 Chen SY, Xie C, Zhu H, Shen Y. Effects of epidermal growth factor on transforming growth factor-beta1-induced epithelial-mesenchymal transition and potential mechanism in human corneal epithelial cells Int J Ophthalmol 2020 13(1):11-20 PubMed ID: 31956565 DOI: 10.18240/ijo.2020.01.03

14864 Zambrano-Andazol I, Vázquez N, Chacón M, Sánchez-Avila RM, Persinal M, Blanco C, González Z, Menéndez R, Sierra M, Fernández-Vega Á, Sánchez T, Merayo-Lloves J, Meana Á. Reduced graphene oxide membranes in ocular regenerative medicine Mater Sci Eng C Mater Biol Appl 2020 114:111075 PubMed ID: 32993970 DOI: 10.1016/j.msec.2020.111075

14871 Wang G, Chen P, Wang Y, Wang Y, Reinach PS, Xue Y, Liu Z, Li C. Onion Epithelial Membrane Scaffolds Transfer Corneal Epithelial Layers in Reconstruction Surgery Adv Healthc Mater 2020 9(14):e2000469 PubMed ID: 32548957 DOI: 10.1002/adhm.202000469

15662 Magny R, Kessal K, Regazzetti A, Ben Yedder A, Baudouin C, Mélik Parsadaniantz S, Brignole-Baudouin F, Laprévote O, Auzeil N. Lipidomic analysis of epithelial corneal cells following hyperosmolarity and benzalkonium chloride exposure: New insights in dry eye disease Biochim Biophys Acta Mol Cell Biol Lipids 2020 1865(9):15872 PubMed ID: 32438057 DOI: 10.1016/j.bbalip.2020.158728

16665 Lee C, Edman MC, Laurie GW, Hamm-Alvarez SF, MacKay JA. Biosynthesized Multivalent Lacritin Peptides Stimulate Exosome Production in Human Corneal Epithelium Int J Mol Sci 2020 21(17):6157 PubMed ID: 32859014 DOI: 10.3390/ijms21176157

16686 Han Y, Jiang N, Su T, Yang QC, Yan CC, Ye L, Yuan Q, Zhu PW, Li W, Liu ZG, Shao Y. Netrin-1 promotes epithelium repair in corneal injury Int J Ophthalmol 2020 13(2):206-212 PubMed ID: 32090028 DOI: 10.18240/ijo.2020.02.02

16688 Yang Y, Huang C, Lin X, Wu Y, Ouyang W, Tang L, Ye S, Wang Y, Li W, Zhang X, Liu Z. Long-Term Exposure to Urban Particulate Matter on the Ocular Surface and the Incidence of Deleterious Changes in the Cornea, Conjunctiva and Retina in Rats Int J Mol Sci 2020 21(14):4976 PubMed ID: 32674521 DOI: 10.3390/ijms21144976

16689 Kang WS, Choi H, Jang G, Lee KH, Kim E, Kim KJ, Jeong GY, Kim JS, Na CS, Kim S. Dry eye induced by exposure to cigarette smoke pollution: An in vivo and in vitro study Free Radic Biol Med 2020 187-201 PubMed ID: 32320747 DOI: 10.1016/j.freeradbiomed.2020.04.007

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11595 Koyama S, Narita E, Suzuki Y, Shiina T, Taki M, Shinohara N, Miyakoshi J. Long-term exposure to a 40-GHz electromagnetic field does not affect genotoxicity or heat shock protein expression in HCE-T or SRA01/04 cells. J. Radiat. Res. 2019 PubMed ID: 31197350 DOI: 10.1093/jrr/rrz017

11636 Kawata K, Aoki S, Futamata M, Yamamoto-Rikitake M, Nakao I, Enaida H, Toda S. Mesenchymal cells and fluid flow stimulation synergistically regulate the kinetics of corneal epithelial cells at the air-liquid interface. Graefes Arch. Clin. Exp. Ophthalmol. 2019 PubMed ID: 31321523 DOI: 10.1007/s00417-019-04422-y

11661 Panita Suwannoi, Mullika Chomnawang, Amolnat Tunsirikongkon, Angsuma Phongphisutthinan, Christel C.Müller-Goymann, Narong Sarisuta TAT-surface modified acyclovir-loaded albumin nanoparticles as a novel ocular drug delivery system Journal of Drug Delivery Science and Technology 2019 DOI: 10.1016/j.jddst.2019.05.029

11818 Dukovski BJ, Bračko A, Šare M, Pepić I, Lovrić J. In vitro evaluation of stearylamine cationic nanoemulsions for improved ocular drug delivery. Acta Pharm 2019 PubMed ID: 31639085 DOI: 10.2478/acph-2019-0054

6948 Tong L, Matsuura E, Takahashi M, Nagano T, Kawazu K. Effects of Anti-Glaucoma Prostaglandin Ophthalmic Solutions on Cultured Human Corneal Epithelial Cells. Curr Eye Res 2019 44(8):856-862 PubMed ID: 30884982 DOI: 10.1080/02713683.2019.1597127

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9139 Guoliang Wang, Yuhua Xue, Yanzi Wang, Fei Dong, Mei Shen, Rongrong Zong, Zuguo Liu, Cheng Li The Role of Autophagy in the Pathogenesis of Exposure Keratitis J Cell Mol Med 2019 23 (6), 4217-4228 PubMed ID: 30973208 DOI: 10.1111/jcmm.14310

10688 Noriko Yaekashiwa, Hisa Yoshida, Sato Otsuki, Shin’ichiro Hayashi and Kodo Kawase Verification of Non-thermal Effects of 0.3–0.6 THz-Waves on Human Cultured Cells Photonics 2019 6(1):33 DOI: 10.3390/photonics6010033

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12325 Zorzi GK, Schuh RS, Maschio VJ, Brazil NT, Rott MB, Teixeira HF. Box Behnken design of siRNA-loaded liposomes for the treatment of a murine model of ocular keratitis caused by Acanthamoeba Colloids Surf B Biointerfaces 2019 173:725-732. PubMed ID: 30384269 DOI: 10.1016/j.colsurfb.2018.10.044

12416 Nagai N, Ogata F, Otake H, Nakazawa Y, Kawasaki N. Energy-dependent endocytosis is responsible for drug transcorneal penetration following the instillation of ophthalmic formulations containing indomethacin nanoparticles Int J Nanomedicine 2019 14:1213-1227 PubMed ID: 30863055 DOI: 10.2147/IJN.S196681

12417 Zhang X, Yin Y, Yue L, Gong L. Selective Serotonin Reuptake Inhibitors Aggravate Depression-Associated Dry Eye Via Activating the NF-κB Pathway Invest Ophthalmol Vis Sci 2019 60(1):407-419 PubMed ID: 30695093 DOI: 10.1167/iovs.18-25572

12418 Žiniauskaitė A, Ragauskas S, Ghosh AK, Thapa R, Roessler AE, Koulen P, Kalesnykas G, Hakkarainen JJ, Kaja S. Manganese(III) tetrakis(1-methyl-4-pyridyl) porphyrin, a superoxide dismutase mimetic, reduces disease severity in in vitro and in vivo models for dry-eye disease Ocul Surf 2019 17(2):257-264 PubMed ID: 30807830 DOI: 10.1016/j.jtos.2019.02.006

12419 Miyakoshi J, Tonomura H, Koyama S, Narita E, Shinohara N. Effects of Exposure to 5.8 GHz Electromagnetic Field on Micronucleus Formation, DNA Strand Breaks, and Heat Shock Protein Expressions in Cells Derived From Human Eye IEEE Trans Nanobioscience 2019 18(2):257-260 PubMed ID: 30892224 DOI: 10.1109/TNB.2019.2905491

14892 An S, Raju I, Surenkhuu B, Kwon JE, Gulati S, Karaman M, Pradeep A, Sinha S, Mun C, Jain S. Neutrophil extracellular traps (NETs) contribute to pathological changes of ocular graft-vs.-host disease (oGVHD) dry eye: Implications for novel biomarkers and therapeutic strategies Ocul Surf 2019 17(3):589-614 PubMed ID: 30965123 DOI: 10.1016/j.jtos.2019.03.010

15097 Kojima H, Yamaguchi H, Sozu T, Kleinstreuer N, Chae-Hyung L, Chen W, Watanabe M, Fukuda T, Yamashita K, Takezawa T. Multi-laboratory Validation Study of the Vitrigel-Eye Irritancy Test Method as an Alternative to In Vivo Eye Irritation Testing Altern Lab Anim 2019 47(3-4):140-157 PubMed ID: 31838865 DOI: 10.1177/0261192919886665

16668 Ren N, Sun R, Xia K, Zhang Q, Li W, Wang F, Zhang X, Ge Z, Wang L, Fan C, Zhu Y. DNA-Based Hybrid Hydrogels Sustain Water-Insoluble Ophthalmic Therapeutic Delivery against Allergic Conjunctivitis ACS Appl Mater Interfaces 2019 11(30):26704-26710 PubMed ID: 31264833 DOI: 10.1021/acsami.9b08652

16670 Klinngam W, Janga SR, Lee C, Ju Y, Yarber F, Shah M, Guo H, Wang D, MacKay JA, Edman MC, Hamm-Alvarez SF. Inhibition of Cathepsin S Reduces Lacrimal Gland Inflammation and Increases Tear Flow in a Mouse Model of Sjögren's Syndrome Sci Rep 2019 9(1):9559 PubMed ID: 31267034 DOI: 10.1038/s41598-019-45966-7

10627 Beißner N, Zorn-Kruppa M, Reichl S. Parameter study of shipping conditions for the ready-to-use application of a 3D human hemicornea construct in drug absorption studies. Int J Pharm 2018 536:377-387 PubMed ID: 29191484 DOI: 10.1016/j.ijpharm.2017.11.057

10824 Juretić M, Cetina-Čižmek B, Filipović-Grčić J, Hafner A, Lovrić J, Pepić I. Biopharmaceutical evaluation of surface active ophthalmic excipients using in vitro and ex vivo corneal models. Eur J Pharm Sci 2018 120:133-141 PubMed ID: 29702232 DOI: 10.1016/j.ejps.2018.04.032

11118 Yin Y, Zong R, Bao X, Zheng X, Cui H, Liu Z, Zhou Y. Oxidative Stress Suppresses Cellular Autophagy in Corneal Epithelium. Invest. Ophthalmol. Vis. Sci. 2018 59(8):3286-3293 PubMed ID: 29971448 DOI: 10.1167/iovs.18-24057

11136 Gillies PJ, Richardson NA, Walshe J, Stephenson SA, Dawson RA, Harkin DG. Demonstration of P-selectin expression and potential function in human corneal epithelial cells. Exp. Eye Res. 2018 176:196-206 PubMed ID: 30025918 DOI: 10.1016/j.exer.2018.07.018

11142 Marek V, Melik-Parsadaniantz S, Villette T, Montoya F, Baudouin C, Brignole-Baudouin F, Denoyer A. Blue light phototoxicity toward human corneal and conjunctival epithelial cells in basal and hyperosmolar conditions. Free Radic. Biol. Med. 2018 126:27-40 PubMed ID: 30040995 DOI: 10.1016/j.freeradbiomed.2018.07.012

11175 Png E, Hou A, Tong L. Mechanistic role of transglutaminase-2 in focal adhesions. Sci Rep 2018 8(1):12370 PubMed ID: 30120307 DOI: 10.1038/s41598-018-30172-8

11291 von Deylen D, Dreher C, Seidelmann O, Reichl S. New Classes of Polycationic Compounds as Preservatives for Ophthalmic Formulations. Pharm. Res. 2018 PubMed ID: 30411196 DOI: 10.1007/s11095-018-2536-9

11370 Xu P, Kai C, Kawasaki S, Kobayashi Y, Yamamoto K, Tsujikawa M, Hayashi R, Nishida K. A New in Vitro Model of GDLD by Knocking Out TACSTD2 and Its Paralogous Gene EpCAM in Human Corneal Epithelial Cells. Transl Vis Sci Technol 2018 PubMed ID: 30619650 DOI: 10.1167/tvst.7.6.30

4084 Akiko TOJU, Yuko UDAKA, Mayumi TSUJI, Hideto OYAMADA, Junichiro KIZAKI, Eiji TOMOYORI, Yuji KIUCHI Suppressive Effects of Catechins in UV-Induced Cytotoxicity of Human Corneal Epithelial Cells Showa Univ J Med Sci 2018 3, 73~85 DOI: 10.15369/sujms.30.73

4191 Krtalić I, Radošević S, Hafner A, Grassi M, Nenadić M, Cetina-Čižmek B, Filipović-Grčić J, Pepić I, Lovrić J. D-Optimal Design in the Development of Rheologically Improved In Situ Forming Ophthalmic Gel. J Pharm Sci 2018 PubMed ID: 29421217 DOI: 10.1016/j.xphs.2018.01.019

4192 Beiβner N, Mattern K, Dietzel A, Reichl S. DynaMiTES - A dynamic cell culture platform for in vitro drug testing PART 2 - Ocular DynaMiTES for drug absorption studies of the anterior eye. Eur J Pharm Biopharm 2018 PubMed ID: 28377274 DOI: 10.1016/j.ejpb.2017.03.021

4193 Klinngam W, Fu R, Janga SR, Edman MC, Hamm-Alvarez SF. Cathepsin S Alters the Expression of Pro-Inflammatory Cytokines and MMP-9, Partially through Protease-Activated Receptor-2, in Human Corneal Epithelial Cells. Int J Mol Sci 2018 PubMed ID: 30423938 DOI: 10.3390/ijms19113530

4477 Tan G, Li J, Yang Q, Wu A, Qu DY, Wang Y, Ye L, Bao J, Shao Y. Air pollutant particulate matter 2.5 induces dry eye syndrome in mice. Sci Rep 2018 8(1):17828 PubMed ID: 30546125 DOI: 10.1038/s41598-018-36181-x

6350 Yamaguchi H, Takezawa T. Fabrication of a Corneal Model Composed of Corneal Epithelial and Endothelial Cells via a Collagen Vitrigel Membrane Functioned as an Acellular Stroma and Its Application to the Corneal Permeability Test of Chemicals. Drug Metab Dispos 2018 46(11):1684-1691 PubMed ID: 29844140 DOI: 10.1124/dmd.118.080820

6351 Shi L, Stachon T, Seitz B, Wagenpfeil S, Langenbucher A, Szentmáry N. The Effect of Antiamoebic Agents on Viability, Proliferation and Migration of Human Epithelial Cells, Keratocytes and Endothelial Cells, In Vitro. Curr Eye Res. 2018 43(6):725-733 PubMed ID: 29528760 DOI: 10.1080/02713683.2018.1447674

6352 Hou A, Tong L. Expression, Regulation, and Effects of Interleukin-17f in the Human Ocular Surface. Ocul Immunol Inflamm 2018 26(7):1069-1077 PubMed ID: 28537453 DOI: 10.1080/09273948.2017.1316411

9462 Vidyarani Mohankumar, Sangeetha Ramalingam, Gowri Priya Chidambaranathan, Lalitha Prajna Autophagy Induced by Type III Secretion System Toxins Enhances Clearance of Pseudomonas Aeruginosa From Human Corneal Epithelial Cells Biochem Biophys Res Commun . 2018 Sep 10;503(3):1510-1515 2018 503(3):1510-1515 PubMed ID: 30031608 DOI: 10.1016/j.bbrc.2018.07.071

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16662 McDermott AM, Baidouri H, Woodward AM, Kam WR, Liu Y, Chen X, Ziemanski JF, Vistisen K, Hazlett LD, Nichols KK, Argüeso P, Sullivan DA. Short Tandem Repeat (STR) Profiles of Commonly Used Human Ocular Surface Cell Lines Curr Eye Res 2018 43(9):1097-1101 PubMed ID: 29787296 DOI: 10.1080/02713683.2018.1480043

16664 Miriem Santander-Borrego, Traian V Chirila, Audra MA Shadforth, Andrew K Whittaker, Idriss Blakey Effect of changes in the surface chemistry and topography of poly(2-hydroxyethyl methacrylate) on the in vitro attachment of human corneal epithelial cells Journal of Bioactive and Compatible Polymers 2018 33:321-331 DOI: 10.1177/0883911517744572

16687 Yang Y, Huang C, Lin X, Wu Y, Ouyang W, Tang L, Ye S, Wang Y, Li W, Zhang X, Liu Z. 0.005% Preservative-Free Latanoprost Induces Dry Eye-Like Ocular Surface Damage via Promotion of Inflammation in Mice Invest Ophthalmol Vis Sci 2018 59(8):3375-3384 PubMed ID: 30025085 DOI: 10.1167/iovs.18-24013

9755 Wu MF, Stachon T, Langenbucher A, Seitz B, Szentmáry N. Effect of Amniotic Membrane Suspension (AMS) and Amniotic Membrane Homogenate (AMH) on Human Corneal Epithelial Cell Viability, Migration and Proliferation In Vitro. Curr. Eye Res. 2017 42:351-357 PubMed ID: 27420558 DOI: 10.1080/02713683.2016.1192193

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9974 Santander-Borrego M, Taran E, Shadforth AM, Whittaker AK, Chirila TV, Blakey I. Hydrogels with Lotus Leaf Topography: Investigating Surface Properties and Cell Adhesion. Langmuir 2017 33:485-493 PubMed ID: 28054787 DOI: 10.1021/acs.langmuir.6b03547

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10251 Nishida T, Kuse Y, Mochizuki K, Shimazawa M, Yamamoto T, Hara H. Protective effects of fluoroquinolones on UV-induced damage of cultured ocular cell lines. Eur. J. Pharmacol. 2017 806:59-66 PubMed ID: 28395990 DOI: 10.1016/j.ejphar.2017.04.004

10412 Hou A, Tin MQ, Tong L. Toll-like receptor 2-mediated NF-kappa B pathway activation in ocular surface epithelial cells. Eye Vis (Lond) 2017 4:17 PubMed ID: 28706958 DOI: 10.1186/s40662-017-0082-x

10983 Meng Z, Klinngam W, Edman MC, Hamm-Alvarez SF. Interferon-γ treatment in vitro elicits some of the changes in cathepsin S and antigen presentation characteristic of lacrimal glands and corneas from the NOD mouse model of Sjo¨gren’s Syndrome PLoS One 2017 12:e0184781 PubMed ID: 28902875 DOI: 10.1371/journal.pone.0184781

6348 Rat P, Olivier E, Tanter C, Wakx A, Dutot M. A fast and reproducible cell- and 96-well plate-based method for the evaluation of P2X7 receptor activation using YO-PRO-1 fluorescent dye. J Biol Methods 2017 4(1):e64 PubMed ID: 31453224 DOI: 10.14440/jbm.2017.136

6353 Faber K, Zorzi GK, Brazil NT, Rott MB, Teixeira HF. siRNA-loaded liposomes: Inhibition of encystment of Acanthamoeba and toxicity on the eye surface. Chem Biol Drug Des 2017 90(3):406-416 PubMed ID: 28135787 DOI: 10.1111/cbdd.12958

4818 Chirila TV, Suzuki S1, Papolla C. A comparative investigation of Bombyx mori silk fibroin hydrogels generated by chemical and enzymatic cross-linking. Biotechnol Appl Biochem 2017 64(6):771-781 PubMed ID: 28220960 DOI: 10.1002/bab.1552

14237 Wu MF, Stachon T, Seitz B, Langenbucher A, Szentmáry N. Effect of human autologous serum and fetal bovine serum on human corneal epithelial cell via Int J Ophthalmol 2017 10(6):908-913 PubMed ID: 28730081 DOI: 10.18240/ijo.2017.06.12

14359 Fukuda K, Ishida W, Miura Y, Kishimoto T, Fukushima A. Cytokine expression and barrier disruption in human corneal epithelial cells induced by alarmin released from necrotic cells Jpn J Ophthalmol 2017 61(5):415-422 PubMed ID: 28725984 DOI: 10.1007/s10384-017-0528-7

14573 Li J, Tan G, Ding X, Wang Y, Wu A, Yang Q, Ye L, Shao Y. A mouse dry eye model induced by topical administration of the air pollutant particulate matter 10 Biomed Pharmacother 2017 96:524-534 PubMed ID: 29032336 DOI: 10.1016/j.biopha.2017.10.032

14610 Zheng X, Cui H, Yin Y, Zhang Y, Zong R, Bao X, Ma JX, Liu Z, Zhou Y. SERPINA3K Ameliorates the Corneal Oxidative Injury Induced by 4-Hydroxynonenal Invest Ophthalmol Vis Sci 2017 58(7):2874-2883 PubMed ID: 28586911 DOI: 10.1167/iovs.17-21544

14678 Kong B, Sun W, Chen G, Tang S, Li M, Shao Z, Mi S. Tissue-engineered cornea constructed with compressed collagen and laser-perforated electrospun mat Sci Rep 2017 7(1):970 PubMed ID: 28428541 DOI: 10.1038/s41598-017-01072-0

7260 Wu MF, Stachon T, Wang J, Song X, Colanesi S, Seitz B, Wagenpfeil S, Langenbucher A, Szentmary N. Effect of Keratocyte Supernatant on Epithelial Cell Migration and Proliferation After Corneal Crosslinking (CXL). Curr. Eye Res. 2016 41:466-73 PubMed ID: 26236938 DOI: 10.3109/02713683.2015.1050739

9715 Esaki Y, Shimazaki A, Pellinen P. Ocular Tolerability of Preservative-Free Tafluprost and Latanoprost: in vitro and in vivo Comparative Study. Open Ophthalmol J 2016 10:146-53 PubMed ID: 27347250 DOI: 10.2174/1874364101610010146

9744 Hakkarainen JJ, Reinisalo M, Ragauskas S, Seppänen A, Kaja S, Kalesnykas G. Acute cytotoxic effects of marketed ophthalmic formulations on human corneal epithelial cells. Int J Pharm 2016 511:73-78 PubMed ID: 27374205 DOI: 10.1016/j.ijpharm.2016.06.135

9749 Fuwa M, Ueda K, Akaishi T, Yamashita N, Kirihara T, Shimazaki A, Mano H, Kawazu K. Advantages of Efficacy and Safety of Fixed-Dose Tafluprost/Timolol Combination Over Fixed-Dose Latanoprost/Timolol Combination. PLoS ONE 2016 11:e0158797 PubMed ID: 27383260 DOI: 10.1371/journal.pone.0158797

9778 Koyama S, Narita E, Shimizu Y, Suzuki Y, Shiina T, Taki M, Shinohara N, Miyakoshi J. Effects of Long-Term Exposure to 60 GHz Millimeter-Wavelength Radiation on the Genotoxicity and Heat Shock Protein (Hsp) Expression of Cells Derived from Human Eye. Int J Environ Res Public Health 2016 13: PubMed ID: 27509516 DOI: 10.3390/ijerph13080802

9779 Koyama S, Narita E, Shimizu Y, Shiina T, Taki M, Shinohara N, Miyakoshi J. Twenty Four-Hour Exposure to a 0.12 THz Electromagnetic Field Does Not Affect the Genotoxicity, Morphological Changes, or Expression of Heat Shock Protein in HCE-T Cells. Int J Environ Res Public Health 2016 13: PubMed ID: 27527204 DOI: 10.3390/ijerph13080793

9965 Utsunomiya T, Ishibazawa A, Nagaoka T, Hanada K, Yokota H, Ishii N, Yoshida A. Transforming Growth Factor-β Signaling Cascade Induced by Mechanical Stimulation of Fluid Shear Stress in Cultured Corneal Epithelial Cells. Invest. Ophthalmol. Vis. Sci. 2016 57:6382-6388 PubMed ID: 27898984 DOI: 10.1167/iovs.16-20638

10034 Jamil B, Abbasi R, Abbasi S, Imran M, Khan SU, Ihsan A, Javed S, Bokhari H, Imran M. Encapsulation of Cardamom Essential Oil in Chitosan Nano-composites: In-vitro Efficacy on Antibiotic-Resistant Bacterial Pathogens and Cytotoxicity Studies. Front Microbiol 2016 7:1580 PubMed ID: 27757108 DOI: 10.3389/fmicb.2016.01580

5426 Kadmiel M, Janoshazi A, Xu X, Cidlowski JA. Glucocorticoid action in human corneal epithelial cells establishes roles for corticosteroids in wound healing and barrier function of the eye. Exp Eye Res 2016 152:10-33 PubMed ID: 27600171 DOI: 10.1016/j.exer.2016.08.020

6347 Yamaguchi H, Kojima H, Takezawa T. Predictive performance of the Vitrigel-eye irritancy test method using 118 chemicals. J Appl Toxicol 2016 36(8):1025-37 PubMed ID: 26472347 DOI: 10.1002/jat.3254

6355 Kölln C, Reichl S Expression of glutathione transferases in corneal cell lines, corneal tissues and a human cornea construct. Int J Pharm 2016 506(1-2):371-81 PubMed ID: 27113863 DOI: 10.1016/j.ijpharm.2016.04.053

6356 Kölln C, Reichl S. Cytochrome P450 Activity in Ex Vivo Cornea Models and a Human Cornea Construct. J Pharm Sci 2016 105(7):2204-12 PubMed ID: 27212636 DOI: 10.1016/j.xphs.2016.04.010

12973 Zong R, Zhou T, Lin Z, Bao X, Xiu Y, Chen Y, Chen L, Ma JX, Liu Z, Zhou Y. Down-Regulation of MicroRNA-184 Is Associated With Corneal Neovascularization Invest Ophthalmol Vis Sci 2016 57(3):1398-407 PubMed ID: 27018842 DOI: 10.1167/iovs.15-17417

14107 Iqbal J, Saeed A, Shah SJ, al-Rashida M, Shams-ul Mahmood. Biological Evaluation of Azomethine-dihydroquinazolinone Conjugates as Cancer and Cholinesterase Inhibitors Med Chem 2016 12(1):74-82 PubMed ID: 26152145 DOI: 10.2174/1573406411666150708111417

14580 Chen Y, Yang W, Zhang X, Yang S, Peng G, Wu T, Zhou Y, Huang C, Reinach PS, Li W, Liu Z. MK2 inhibitor reduces alkali burn-induced inflammation in rat cornea Sci Rep 2016 6:28145 PubMed ID: 27329698 DOI: 10.1038/srep28145

14582 Kokado M, Okada Y, Miyamoto T, Yamanaka O, Saika S. Effects of epiplakin-knockdown in cultured corneal epithelial cells BMC Res Notes 2016 9:278 PubMed ID: 27206504 DOI: 10.1186/s13104-016-2082-7

11651 Hogerheyde TA, Suzuki S, Walshe J, Bray LJ, Stephenson SA, Harkin DG, Richardson NA. Optimization of Corneal Epithelial Progenitor Cell Growth on Bombyx mori Silk Fibroin Membranes Stem Cells Int 2016 2016:8310127 PubMed ID: 27648078 DOI: 10.1155/2016/8310127

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7500 Verstraelen J, Reichl S. Upregulation of P-glycoprotein expression by ophthalmic drugs in different corneal in-vitro models. J. Pharm. Pharmacol. 2015 67:605-15 PubMed ID: 25643948 DOI: 10.1111/jphp.12357

6337 Xu M, McCanna DJ, Sivak JG. Use of the viability reagent PrestoBlue in comparison with alamarBlue and MTT to assess the viability of human corneal epithelial cells. J Pharmacol Toxicol Methods 2015 71:1-7 PubMed ID: 25464019 DOI: 10.1016/j.vascn.2014.11.003

15032 Pretor S, Bartels J, Lorenz T, Dahl K, Finke JH, Peterat G, Krull R, Al-Halhouli AT, Dietzel A, Büttgenbach S, Behrends S, Reichl S, Müller-Goymann CC. Cellular uptake of coumarin-6 under microfluidic conditions into HCE-T cells from nanoscale formulations Mol Pharm 2015 12(1):34-45 PubMed ID: 25412253 DOI: 10.1021/mp500401t

15065 Arooj S, Nazir S, Nadhman A, Ahmad N, Muhammad B, Ahmad I, Mazhar K, Abbasi R. Novel ZnO:Ag nanocomposites induce significant oxidative stress in human fibroblast malignant melanoma (Ht144) cells Beilstein J Nanotechnol 2015 6:570-82 PubMed ID: 25821698 DOI: 10.3762/bjnano.6.59

15242 Sirajuddin M, Ali S, McKee V, Ullah H. Synthesis, spectroscopic characterization and in vitro antimicrobial, anticancer and antileishmanial activities as well interaction with Salmon sperm DNA of newly synthesized carboxylic acid derivative, 4-(4-methoxy-2-nitrophenylamino)-4-oxobutanoic acid Spectrochim Acta A Mol Biomol Spectrosc 2015 138:569-78 PubMed ID: 25536453 DOI: 10.1016/j.saa.2014.11.061

15480 Chen L, Zong R, Zhou J, Ge L, Zhou T, Ma JX, Liu Z, Zhou Y. The oxidant role of 4-hydroxynonenal in corneal epithelium Sci Rep 2015 5:10630 PubMed ID: 26023743 DOI: 10.1038/srep10630

15505 Bartok M, Gabel D, Zorn-Kruppa M, Engelke M. Development of an in vitro ocular test system for the prediction of all three GHS categories Toxicol In Vitro 2015 29(1):72-80 PubMed ID: 25260822 DOI: 10.1016/j.tiv.2014.09.005

6330 Shibata Y, Tanaka Y, Tomita T, Taogoshi T, Kimura Y, Chikama T, Kihira K. Evaluation of corneal damage caused by iodine preparations using human corneal epithelial cells. Jpn J Ophthalmol 2014 58(6):522-7 PubMed ID: 25230910 DOI: 10.1007/s10384-014-0348-y

6332 Wang W, Despanie J, Shi P, Edman-Woolcott MC, Lin YA, Cui H, Heur JM, Fini ME, Hamm-Alvarez SF, MacKay JA. Lacritin-mediated regeneration of the corneal epithelia by protein polymer nanoparticles. J Mater Chem B 2014 2(46):8131-8141 PubMed ID: 25530855 DOI: 10.1039/C4TB00979G

6357 Wen L, Zhu M, Madigan MC, You J, King NJ, Billson FA, McClellan K, Sutton G, Petsoglou C2 Immunomodulatory effects of bone marrow-derived mesenchymal stem cells on pro-inflammatory cytokine-stimulated human corneal epithelial cells. PLoS One. 2014 9(7):e101841 PubMed ID: 25003339 DOI: 10.1371/journal.pone.0101841

6358 Sharma S, Gupta D, Mohanty S, Jassal M, Agrawal AK, Tandon R. Surface-modified electrospun poly(epsilon-caprolactone) scaffold with improved optical transparency and bioactivity for damaged ocular surface reconstruction. Invest Ophthalmol Vis Sci 2014 55(2):899-907 PubMed ID: 24425860 DOI: 10.1167/iovs.13-12727

6359 Mahita Kadmiel, John A Cidlowski Functional Characterization of the Glucocorticoid Receptor in the Cornea Investigative Ophthalmology & Visual Science 2014 55:5504

6360 Anitua E, Muruzabal F, De la Fuente M, Merayo-Lloves J, Orive G. Effects of heat-treatment on plasma rich in growth factors-derived autologous eye drop. Exp Eye Res 2014 119:27-34 PubMed ID: 24345372 DOI: 10.1016/j.exer.2013.12.005

15099 Zorn-Kruppa M, Houdek P, Wladykowski E, Engelke M, Bartok M, Mewes KR, Moll I, Brandner JM. Determining the Depth of Injury in Bioengineered Tissue Models of Cornea and Conjunctiva for the Prediction of All Three Ocular GHS Categories PLoS One 2014 9(12):e114181 PubMed ID: 25494045 DOI: 10.1371/journal.pone.0114181

15833 Ko JA, Mizuno Y, Ohki C, Chikama T, Sonoda KH, Kiuchi Y. Neuropeptides released from trigeminal neurons promote the stratification of human corneal epithelial cells Invest Ophthalmol Vis Sci 2014 55(1):125-33 PubMed ID: 24327615 DOI: 10.1167/iovs.13-12642

15995 Friedrich Erben, Dirk Michalik, Holger Feist, Dennis Kleeblatt, Martin Hein, Abdul Matin, Jamshed Iqbal, Peter Langer Synthesis and antiproliferative activity of (Z)-1-glycosyl-3-(5-oxo-2-thioxoimidazolidin-4-ylidene)indolin-2-ones and (Z)-3-(2-glycosylsulfanyl-4-oxo-4,5-dihydro-thiazol-5-ylidene)indolin-2-ones RSC Advances 2014 4:10879 DOI: 10.1039/c3ra44362k

16002 Wright B, De Bank PA, Luetchford KA, Acosta FR, Connon CJ. Oxidized alginate hydrogels as niche environments for corneal epithelial cells J Biomed Mater Res A 2014 102(10):3393-400 PubMed ID: 24142706 DOI: 10.1002/jbm.a.35011

6364 Wang N, Zimmerman K, Raab RW, McKown RL, Hutnik CM, Talla V, Tyler MF 4th, Lee JK, Laurie GW. Lacritin rescues stressed epithelia via rapid forkhead box O3 (FOXO3)-associated autophagy that restores metabolism. J Biol Chem. 2013. 288(25):18146-61 PubMed ID: 23640897 DOI: 10.1074/jbc.M112.436584

19070 Sasaki H, Karasawa K, Hironaka K, Tahara K, Tozuka Y, Takeuchi H. Retinal drug delivery using eyedrop preparations of poly-L-lysine-modified liposomes Eur J Pharm Biopharm 2013 83(3):364-9. PubMed ID: 23153668 DOI: 10.1016/j.ejpb.2012.10.014

6323 Xu M, Sivak JG, McCanna DJ. Comparison of the effects of ophthalmic solutions on human corneal epithelial cells using fluorescent dyes. J Ocul Pharmacol Ther 2013 29(9):794-802 PubMed ID: 23905770 DOI: 10.1089/jop.2013.0002

6324 Yamaguchi H, Kojima H, Takezawa T. Vitrigel-eye irritancy test method using HCE-T cells. Toxicol Sci 2013 135(2):347-55 PubMed ID: 23872712 DOI: 10.1093/toxsci/kft159

6325 Rahimi M, Youn HY, McCanna DJ, Sivak JG, Mikkelsen SR. Application of cyclic biamperometry to viability and cytotoxicity assessment in human corneal epithelial cells. Anal Bioanal Chem 2013 405(14):4975-9 PubMed ID: 23443523 DOI: 10.1007/s00216-013-6843-z

6327 Tong L, Png E, Aihua H, Yong SS, Yeo HL, Riau A, Mendoz E, Chaurasia SS, Lim CT, Yiu TW, Iismaa SE. Molecular mechanism of transglutaminase-2 in corneal epithelial migration and adhesion. Biochim Biophys Acta. 2013 1833(6):1304-15 PubMed ID: 23466867 DOI: 10.1016/j.bbamcr.2013.02.030

6328 Hiroyoshi Kasai et al Comparison of efficacy and safety evaluation of latanoprost formulations with and without benzalkonium chloride Pharmacology & Pharmacy 2013 4:377-384 DOI: 10.4236/pp.2013.44054

6361 Verstraelen J, Reichl S. Expression analysis of MDR1, BCRP and MRP3 transporter proteins in different in vitro and ex vivo cornea models for drug absorption studies. Int J Pharm 2013 441(1-2):765-75 PubMed ID: 23069916 DOI: 10.1016/j.ijpharm.2012.10.007

6362 Borrelli M, Reichl S, Feng Y, Schargus M, Schrader S, Geerling G. In vitro characterization and ex vivo surgical evaluation of human hair keratin films in ocular surface reconstruction after sterilization processing. J Mater Sci Mater Med 2013 24(1):221-30 PubMed ID: 23015265 DOI: 10.1007/s10856-012-4774-4

6363 Hogerheyde TA, Stephenson SA, Harkin DG, Bray LJ, Madden PW, Woolf MI, Richardson NA. Evaluation of Eph receptor and ephrin expression within the human cornea and limbus. Exp Eye Res 2013 107:110-20 PubMed ID: 23247085 DOI: 10.1016/j.exer.2012.11.016

6365 Raju R, Jian B, Hooks JJ, Nagineni CN. Transforming growth factor-β regulates the expression of anosmin (KAL-1) in human retinal pigment epithelial cells. Cytokine 2013 61(3):724-7 PubMed ID: 23357298 DOI: 10.1016/j.cyto.2012.12.019

6333 George KA, Shadforth AM, Chirila TV, Laurent MJ, Stephenson SA, Edwards GA, Madden PW, Hutmacher DW, Harkin DG. Effect of the sterilization method on the properties of Bombyx mori silk fibroin films. Mater Sci Eng C Mater Biol Appl 2013 33(2):668-74 PubMed ID: 25427472 DOI: 10.1016/j.msec.2012.10.016

6366 Anitua E, Muruzabal F, Alcalde I, Merayo-Lloves J, Orive G. Plasma rich in growth factors (PRGF-Endoret) stimulates corneal wound healing and reduces haze formation after PRK surgery. Exp Eye Res 2013 115:153-61 PubMed ID: 23872360 DOI: 10.1016/j.exer.2013.07.007

6367 Paterson SM, Shadforth AM, Shaw JA, Brown DH, Chirila TV, Baker MV. Improving the cellular invasion into PHEMA sponges by incorporation of the RGD peptide ligand: the use of copolymerization as a means to functionalize PHEMA sponges. Mater Sci Eng C Mater Biol Appl 2013 33(8):4917-22 PubMed ID: 24094205 DOI: 10.1016/j.msec.2013.08.011

6368 Engelke M, Zorn-Kruppa M, Gabel D, Reisinger K, Rusche B, Mewes KR. A human hemi-cornea model for eye irritation testing: quality control of production, reliability and predictive capacity. Toxicol In Vitro 2013 27(1):458-68 PubMed ID: 22902307 DOI: 10.1016/j.tiv.2012.07.011

14321 Dutot M, Vincent J, Martin-Brisac N, Fabre I, Grasmick C, Rat P. Ocular cytotoxicity evaluation of medical devices such as contact lens solutions and benefits of a rinse step in cleaning procedure ALTEX 2013 30(1):41-9. PubMed ID: 23338805 DOI: 10.14573/altex.2013.1.041

15778 Fukuda K, Ishida W, Tanaka H, Harada Y, Matsuda A, Ebihara N, Fukushima A. Alarmins from corneal epithelial cells upregulate CCL11 and VCAM-1 in corneal fibroblasts Invest Ophthalmol Vis Sci 2013 54(8):5817-23 PubMed ID: 23920370 DOI: 10.1167/iovs.13-11969

15787 Guo H, Du G, Wang L, Wang D, Hu L, Huang Y. Integrin alpha v beta 6 contributes to maintaining corneal epithelial barrier function Cell Biol Int 2013 37(6):593-9 PubMed ID: 23412966 DOI: 10.1002/cbin.10076

15934 Hafiz Muhammad Shoaib 1 , Ambreen Gul Muazzam, Asif Mir, Suk-Yul Jung, Abdul Matin Evaluation of inhibitory potential of some selective methanolic plants extracts on biological characteristics of Acanthamoeba castellanii using human corneal epithelial cells in vitro Parasitol Res 2013 112(3):1179-88 PubMed ID: 23306385 DOI: 10.1007/s00436-012-3249-3

16088 Iqbal J, Saeed A, Raza R, Matin A, Hameed A, Furtmann N, Lecka J, Sévigny J, Bajorath J. Identification of sulfonic acids as efficient ecto-5'-nucleotidase inhibitors Eur J Med Chem 2013 70:685-91 PubMed ID: 24215819 DOI: 10.1016/j.ejmech.2013.10.053

6315 Liang H, Baudouin C, Daull P, Garrigue JS, Brignole-Baudouin F. Ocular safety of cationic emulsion of cyclosporine in an in vitro corneal wound-healing model and an acute in vivo rabbit model. Mol Vis 2012 18:2195-204 PubMed ID: 22919267

6369 Hattori M, Shimizu K, Katsumura K, Oku H, Sano Y, Matsumoto K, Yamaguchi Y, Ikeda T. Effects of all-trans retinoic acid nanoparticles on corneal epithelial wound healing. Graefes Arch Clin Exp Ophthalmol 2012 250(4):557-63 PubMed ID: 22048243 DOI: 10.1007/s00417-011-1849-8

6370 Kinoshita S, Kawasaki S, Kitazawa K, Shinomiya K. Establishment of a human conjunctival epithelial cell line lacking the functional TACSTD2 gene (an American Ophthalmological Society thesis). Trans Am Ophthalmol Soc 2012 110:166-77 PubMed ID: 23818740

6371 Hahne M, Zorn-Kruppa M, Guzman G, Brandner JM, Haltner-Ukomado E, Wätzig H, Reichl S. Prevalidation of a human cornea construct as an alternative to animal corneas for in vitro drug absorption studies. J Pharm Sci 2012 101(8):2976-88 PubMed ID: 22581751 DOI: 10.1002/jps.23190

6372 Stefan M.Paterson et al The synthesis and degradation of collagenase-degradable poly(2-hydroxyethyl methacrylate)-based hydrogels and sponges for potential applications as scaffolds in tissue engineering Materials Science and Engineering: C 2012 32:2536-2544 DOI: 10.1016/j.msec.2012.07.037

9093 Bernice Wright, Richard A Cave, Joseph P Cook, Vitaliy V Khutoryanskiy, Shengli Mi, Bo Chen, Martin Leyland, Che J Connon Enhanced Viability of Corneal Epithelial Cells for Efficient Transport/Storage Using a Structurally Modified Calcium Alginate Hydrogel Regen Med2 2012 7 (3), 295-307 PubMed ID: 22594324 DOI: 10.2217/rme.12.7

15761 Zhou T, Zong R, Zhang Z, Zhu C, Pan F, Xiao X, Liu Z, He H, Ma JX, Liu Z, Zhou Y. SERPINA3K protects against oxidative stress via modulating ROS generation/degradation and KEAP1-NRF2 pathway in the corneal epithelium Invest Ophthalmol Vis Sci 2012 53(8):5033-43 PubMed ID: 22736614 DOI: 10.1167/iovs.12-9729

16034 Shinya Hattori, Dohiko Terada, Andreana Bibin Bintang, Takako Honda, Chiaki Yoshikawa, Hidetoshi Teramoto, Tsunenori Kameda, Tamada Yasushi, Hisatoshi Kobayashi Influence of sterilisations on silk protein-based materials Bioinspired, Biomimetic and Nanobiomaterials 2012 1:195-199 DOI: 10.1680/bbn.11.00006

7623 Sharma S, Mohanty S, Gupta D, Jassal M, Agrawal AK, Tandon R. Cellular response of limbal epithelial cells on electrospun poly-ε-caprolactone nanofibrous scaffolds for ocular surface bioengineering: a preliminary in vitro study. Mol. Vis. 2011 17:2898-910 PubMed ID: 22128237

7815 Kato M, Hagiwara Y, Oda T, Imamura-Takai M, Aono H, Nakamura M. Beneficial pharmacological effects of selective glucocorticoid receptor agonist in external eye diseases. J Ocul Pharmacol Ther 2011 27:353-60 PubMed ID: 21574866 DOI: 10.1089/jop.2010.0177

7894 Png E, Lan W, Lazaroo M, Chen S, Zhou L, Tong L. A new method of high-speed cellular protein separation and insight into subcellular compartmentalization of proteins. Anal Bioanal Chem 2011 400:767-75 PubMed ID: 21380751 DOI: 10.1007/s00216-011-4810-0

7974 Youn HY, McCanna DJ, Sivak JG, Jones LW. In vitro ultraviolet-induced damage in human corneal, lens, and retinal pigment epithelial cells. Mol. Vis. 2011 17:237-46 PubMed ID: 21270970

8152 Png E, Samivelu GK, Yeo SH, Chew J, Chaurasia SS, Tong L. Hyperosmolarity-mediated mitochondrial dysfunction requires Transglutaminase-2 in human corneal epithelial cells. J. Cell. Physiol. 2011 226:693-9 PubMed ID: 20717931 DOI: 10.1002/jcp.22389

6311 Takezawa T, Nishikawa K, Wang PC. Development of a human corneal epithelium model utilizing a collagen vitrigel membrane and the changes of its barrier function induced by exposing eye irritant chemicals. Toxicol In Vitro 2011 25(6):1237-41 PubMed ID: 21641988 DOI: 10.1016/j.tiv.2011.05.021

12746 Kimura K, Teranishi S, Kawamoto K, Nishida T. Protective effect of dexamethasone against hypoxia-induced disruption of barrier function in human corneal epithelial cells Exp Eye Res 2011 92(5):388-93 PubMed ID: 21354133 DOI: 10.1016/j.exer.2011.02.013

15712 Liu X, Lin Z, Zhou T, Zong R, He H, Liu Z, Ma JX, Liu Z, Zhou Y. Anti-angiogenic and anti-inflammatory effects of SERPINA3K on corneal injury PLoS One 2011 6(1):e16712 PubMed ID: 21304961 DOI: 10.1371/journal.pone.0016712

16306 Kimura K, Teranishi S, Orita T, Zhou H, Nishida T. Role of β-Pix in corneal epithelial cell migration on fibronectin Invest Ophthalmol Vis Sci 2011 52(6):3181-6 PubMed ID: 21228382 DOI: 10.1167/iovs.10-5684

8041 Shah A, Farooq AV, Tiwari V, Kim MJ, Shukla D. HSV-1 infection of human corneal epithelial cells: receptor-mediated entry and trends of re-infection. Mol. Vis. 2010 16:2476-86 PubMed ID: 21139972

6374 Yamada T, Ueda T, Ugawa S, Ishida Y, Imayasu M, Koyama S, Shimada S. Functional expression of transient receptor potential vanilloid 3 (TRPV3) in corneal epithelial cells: involvement in thermosensation and wound healing. Exp Eye Res 2010 90(1):121-9 PubMed ID: 19793539 DOI: 10.1016/j.exer.2009.09.020

9081 Yuki Terasaka, Dai Miyazaki, Keiko Yakura, Tomoko Haruki, Yoshitsugu Inoue Induction of IL-6 in Transcriptional Networks in Corneal Epithelial Cells After Herpes Simplex Virus Type 1 Infection Invest Ophthalmol Vis Sci 2010 51 (5), 2441-9 PubMed ID: 20019363 DOI: 10.1167/iovs.09-4624

12758 Kimura K, Teranishi S, Kawamoto K, Nishida T. Protection of human corneal epithelial cells from hypoxia-induced disruption of barrier function by hepatocyte growth factor Exp Eye Res 2010 90(2):337-43 PubMed ID: 19944686 DOI: 10.1016/j.exer.2009.11.012

15696 Kimura K, Kawano S, Mori T, Inoue J, Hadachi H, Saito T, Nishida T. Quantitative analysis of the effects of extracellular matrix proteins on membrane dynamics associated with corneal epithelial cell motility Invest Ophthalmol Vis Sci 2010 51(9):4492-9 PubMed ID: 20357207 DOI: 10.1167/iovs.09-4380

16663 Imayasu M, Hori Y, Cavanagh HD. Effects of multipurpose contact lens care solutions and their ingredients on membrane-associated mucins of human corneal epithelial cells Eye Contact Lens 2010 36(6):361-6 PubMed ID: 21060261 DOI: 10.1097/ICL.0b013e3181faa43e

11686 Kimura K, Teranishi S, Nishida T. Establishment of human corneal epithelial cells stably expressing human connexin43 Exp Eye Res 2010 90(1):4-9 PubMed ID: 19799899 DOI: 10.1016/j.exer.2009.09.002

8445 Dutot M, Liang H, Martin C, Rousseau D, Grynberg A, Warnet JM, Rat P. Per os administered refined olive oil and marine PUFA-rich oils reach the cornea: possible role on oxidative stress through caveolin-1 modulation. Nutr Metab (Lond) 2009 6:48 PubMed ID: 19930652 DOI: 10.1186/1743-7075-6-48

8502 Pauloin T, Dutot M, Liang H, Chavinier E, Warnet JM, Rat P. Corneal protection with high-molecular-weight hyaluronan against in vitro and in vivo sodium lauryl sulfate-induced toxic effects. Cornea 2009 28:1032-41 PubMed ID: 19724206 DOI: 10.1097/ICO.0b013e3181a0a3f8

8624 Pauloin T, Dutot M, Joly F, Warnet JM, Rat P. High molecular weight hyaluronan decreases UVB-induced apoptosis and inflammation in human epithelial corneal cells. Mol. Vis. 2009 15:577-83 PubMed ID: 19325714

8697 Liu L, Tiffany J, Dang Z, Dart JK, Watson SL, Daniels JT, Geerling G. Nourish and nurture: development of a nutrient ocular lubricant. Invest. Ophthalmol. Vis. Sci. 2009 50:2932-9 PubMed ID: 19074805 DOI: 10.1167/iovs.08-1991

19071 Hironaka K, Inokuchi Y, Tozuka Y, Shimazawa M, Hara H, Takeuchi H. Design and evaluation of a liposomal delivery system targeting the posterior segment of the eye J Control Release 2009 136(3):247-53 PubMed ID: 19272407 DOI: 10.1016/j.jconrel.2009.02.020

6376 Karla PK, Quinn TL, Herndon BL, Thomas P, Pal D, Mitra A. Expression of multidrug resistance associated protein 5 (MRP5) on cornea and its role in drug efflux. J Ocul Pharmacol Ther 2009 25(2):121-32 PubMed ID: 19323627 DOI: 10.1089/jop.2008.0084

9077 Kozaburo Hayashi, Laura C Hooper, Barbara Detrick, John J Hooks HSV Immune Complex (HSV-IgG: IC) and HSV-DNA Elicit the Production of Angiogenic Factor VEGF and MMP-9 Arch Virol 2009 154 (2), 219-26 PubMed ID: 19115032 DOI: 10.1007/s00705-008-0303-7

12767 Kimura K, Teranishi S, Nishida T. Interleukin-1beta-induced disruption of barrier function in cultured human corneal epithelial cells Invest Ophthalmol Vis Sci 2009 50(2):597-603 PubMed ID: 19171646 DOI: 10.1167/iovs.08-2606

16691 Ko JA, Yanai R, Nishida T. Up-regulation of ZO-1 expression and barrier function in cultured human corneal epithelial cells by substance P FEBS Lett 2009 583(12):2148-53 PubMed ID: 19446555 DOI: 10.1016/j.febslet.2009.05.010

16694 Teranishi S, Kimura K, Nishida T. Role of formation of an ERK-FAK-paxillin complex in migration of human corneal epithelial cells during wound closure in vitro Invest Ophthalmol Vis Sci 2009 50(12):5646-52 PubMed ID: 19494198 DOI: 10.1167/iovs.08-2534

18249 Teranishi S, Kimura K, Kawamoto K, Nishida T. Protection of human corneal epithelial cells from hypoxia-induced disruption of barrier function by keratinocyte growth factor Invest Ophthalmol Vis Sci 2008 49(6):2432-7 PubMed ID: 18362114 DOI: 10.1167/iovs.07-1464

8755 Dutot M, Liang H, Pauloin T, Brignole-Baudouin F, Baudouin C, Warnet JM, Rat P. Effects of toxic cellular stresses and divalent cations on the human P2X7 cell death receptor. Mol. Vis. 2008 14:889-97 PubMed ID: 18490962

8777 Alison C. Dunn A Jessica A. Cobb A Ana N. Kantzios A Sung Jin Lee AMalisa Sarntinoranont A Roger Tran-Son-Tay A W. Gregory Sawyer Friction Coefficient Measurement of Hydrogel Materialson Living Epithelial Cells Tribology Letters 2008 30:13-19 DOI: 10.1007/s11249-008-9306-5

8783 Cobb JA, Dunn AC, Kwon J, Sarntinoranont M, Sawyer WG, Tran-Son-Tay R. A novel method for low load friction testing on living cells. Biotechnol. Lett. 2008 30:801-6 PubMed ID: 18071637 DOI: 10.1007/s10529-007-9623-z

6299 Pauloin T, Dutot M, Warnet JM, Rat P. In vitro modulation of preservative toxicity: high molecular weight hyaluronan decreases apoptosis and oxidative stress induced by benzalkonium chloride. Eur J Pharm Sci. 2008 34(4-5):263-73 PubMed ID: 18534829 DOI: 10.1016/j.ejps.2008.04.006

6377 Becker U, Ehrhardt C, Schneider M, Muys L, Gross D, Eschmann K, Schaefer UF, Lehr CM. A comparative evaluation of corneal epithelial cell cultures for assessing ocular permeability. Altern Lab Anim 2008 36(1):33-44 PubMed ID: 18333713 DOI: 10.1177/026119290803600106

6378 Secker GA, Shortt AJ, Sampson E, Schwarz QP, Schultz GS, Daniels JT. TGFbeta stimulated re-epithelialisation is regulated by CTGF and Ras/MEK/ERK signalling. Exp Cell Res 2008 314(1):131-42 PubMed ID: 17915216 DOI: 10.1016/j.yexcr.2007.09.001

6379 Nishikiori N, Sawada N, Ohguro H. Prevention of murine experimental corneal trauma by epigenetic events regulating claudin 6 and claudin 9. Jpn J Ophthalmol 2008 52(3):195-203 PubMed ID: 18661270 DOI: 10.1007/s10384-008-0524-z

6380 Benko S, Tozser J, Miklossy G, Varga A, Kadas J, Csutak A, Berta A, Rajnavolgyi E. Constitutive and UV-B modulated transcription of Nod-like receptors and their functional partners in human corneal epithelial cells. Mol Vis 2008 14:1575-83 PubMed ID: 18769647

12787 Kimura K, Teranishi S, Fukuda K, Kawamoto K, Nishida T. Delayed disruption of barrier function in cultured human corneal epithelial cells induced by tumor necrosis factor-alpha in a manner dependent on NF-kappaB Invest Ophthalmol Vis Sci 2008 49(2):565-71 PubMed ID: 18235000 DOI: 10.1167/iovs.07-0419

15688 Kimura K, Teranishi S, Yamauchi J, Nishida T. Role of JNK-dependent serine phosphorylation of paxillin in migration of corneal epithelial cells during wound closure Invest Ophthalmol Vis Sci 2008 49(1):125-32 PubMed ID: 18172084 DOI: 10.1167/iovs.07-0725

16693 Yanai R, Liu Y, Ko JA, Nishida T. Effects of ambient oxygen concentration on the proliferation and viability of cultured human corneal epithelial cells Exp Eye Res 2008 86(2):412-8 PubMed ID: 18187131 DOI: 10.1016/j.exer.2007.11.014

6292 Miles DH, Thakur A, Cole N, Willcox MD. The induction and suppression of the apoptotic response of HSV-1 in human corneal epithelial cells. Invest Ophthalmol Vis Sci 2007 48(2):789-96 PubMed ID: 17251479 DOI: 10.1167/iovs.06-0609

6381 Ho JH, Chuang CH, Ho CY, Shih YR, Lee OK, Su Y. Internalization is essential for the antiapoptotic effects of exogenous thymosin beta-4 on human corneal epithelial cells. Invest Ophthalmol Vis Sci 2007 48(1):27-33 PubMed ID: 17197512 DOI: 10.1167/iovs.06-0826

15639 Kimura K, Hattori A, Usui Y, Kitazawa K, Naganuma M, Kawamoto K, Teranishi S, Nomizu M, Nishida T. Stimulation of corneal epithelial migration by a synthetic peptide (PHSRN) corresponding to the second cell-binding site of fibronectin Invest Ophthalmol Vis Sci 2007 48(3):1110-8 PubMed ID: 17325153 DOI: 10.1167/iovs.06-0704

8874 Liu L, Hartwig D, Harloff S, Herminghaus P, Wedel T, Kasper K, Geerling G. Corneal epitheliotrophic capacity of three different blood-derived preparations. Invest. Ophthalmol. Vis. Sci. 2006 47:2438-44 PubMed ID: 16723454 DOI: 10.1167/iovs.05-0876