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22414
Takeuchi K, Tabe S, Yamamoto Y, Takahashi K, Matsuo M, Ueno Y, Ohtsuka M, Morinaga S, Miyagi Y, Yamaguchi T, Tanimizu N, Taniguchi H.
Protocol for generating a pancreatic cancer organoid associated with heterogeneous tumor microenvironment.
STAR Protoc
2025
6(1):103539
PubMed ID: 39772386
DOI: 10.1016/j.xpro.2024.103539
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22511
Tweedie L, Riccetti MR, Cain B, Qin S, Salomone J, Webb JA, Riesenberg A, Ehrman LA, Waclaw RR, Kovall RA, Gebelein B, Campbell K.
Modelling a pathological GSX2 variant that selectively alters DNA binding reveals hypomorphic mouse basal ganglia and hindbrain defects.
Dis Model Mech
2025
PubMed ID: 39882631
DOI: 10.1242/dmm.052110
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22557
Tasaki K, Satoda Y, Chiba S, Shin HW, Katoh Y, Nakayama K.
Mutually independent and cilia-independent assembly of IFT-A and IFT-B complexes at mother centriole.
Mol Biol Cell
2025
36(4):ar48
PubMed ID: 40020180
DOI: 10.1091/mbc.E24-11-0509
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22611
Mutmainah, Murai Y, Fujimoto A, Kawamura R, Kitamura A, Koolath S, Usuki S, Sasaki M, Orba Y, Igarashi Y, Sawa H, Sato A, Monde K.
Malabaricone C isolated from edible plants as a potential inhibitor of SARS-CoV-2 infection.
Sci Rep
2025
15(1):8518
PubMed ID: 40074774
DOI: 10.1038/s41598-024-83633-8
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22725
Men Y, Hirayama S, Ao S, Sakurai Y, Shibata Y, Lo M, Sato Y, Murata S.
ESCRT-I and PTPN23 mediate microautophagy of ubiquitylated tau aggregates.
J Cell Biol
2025
224(6)
PubMed ID: 40197510
DOI: 10.1083/jcb.202406120
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22752
Mutai H, Kuroda Y, Noji S, Ichikawa S, Matsuo K, Tanaka S, Kataoka N, Fujioka M, Matsunaga T.
Complete omission of exon 21 from Slc12a2 transcripts in mice results in hearing loss.
Sci Rep
2025
15(1):14790
PubMed ID: 40295800
DOI: 10.1038/s41598-025-99827-7
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22756
Fujimoto S, Endo M, Tonomura S, Tsuji F, Haraguchi H, Hasegawa K, Numao T, Izumi A, Tourtas T, Schlötzer-Schrehardt U, Kruse F, Oyama Y, Ikawa M, Jun AS, Koizumi N, Okumura N.
Therapeutic Potential of Emricasan, a Pan-Caspase Inhibitor, in Reducing Cell Death and Extracellular Matrix Accumulation in Fuchs Endothelial Corneal Dystrophy.
Cells
2025
14(7)
PubMed ID: 40214452
DOI: 10.3390/cells14070498
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22918
Sekiya M, Nakanishi-Matsui M, Matsumoto N, Takahashi I, Hanasaka T, Ishiyama-Matsuura E, Araki M, Wakayama T, Nata K.
The a subunit isoforms of V-ATPase are involved in glucose-dependent trafficking of insulin granules.
Sci Rep
2025
15(1):18982
PubMed ID: 40447629
DOI: 10.1038/s41598-025-02997-7
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22931
Urata S, Lee M, Tsuruta T, Igarashi R, Takeda K, Unno H.
Mode of antiviral action of the galactose-specific lectin, AJLec, on the Junin virus propagation.
Antiviral Res
2025
240:106189
PubMed ID: 40381661
DOI: 10.1016/j.antiviral.2025.106189
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22980
Matsugo H, Kitamura T, Takahashi N, Chambers J, Ichikawa A, Katayama M, Li K, Sekine W, Ohira K, Ishida H, Takenaka-Uema A, Uchida K, Shimojima M, Horimoto T, Murakami S.
In vitro and in vivo characterization of a bat merbecovirus with ACE2- and DPP4-independent cell entry.
J Virol
2025
e0072725
PubMed ID: 40525828
DOI: 10.1128/jvi.00727-25
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22983
Hashimoto T, Saito S, Ohata M, Okuwaki M.
The oncoprotein DEK controls growth-regulated gene expression by enhancing the DNA-binding activity of basic leucine zipper transcription factors
FEBS J
2025
2025 May 2
PubMed ID: 40318137
DOI: 10.1111/febs.70124
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19760
etta Takahashi, Nahoko Tomonobu, Rie Kinoshita, Ken-ichi Yamamoto, Hitoshi Murata, Ni Luh Gede Yoni Komalasari, Youyi Chen, Fan Jiang, Yuma Gohara, Toshiki Ochi, I Made Winarsa Ruma, I Wayan Sumardika, Jin Zhou, Tomoko Honjo, Yoshihiko Sakaguchi, Akira Yamauchi, Futoshi Kuribayashi, Eisaku Kondo, Yusuke Inoue, Junichiro Futami, Shinichi Toyooka, Yoshito Zamami, Masakiyo Sakaguchi
Lysyl oxidase-like 4 promotes the invasiveness of triple-negative breast cancer cells by orchestrating the invasive machinery formed by annexin A2 and S100A11 on the cell surface
Frontiers in Oncology
2024
14
DOI: 10.3389/fonc.2024.1371342
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19794
Nakanishi-Matsui M, Matsumoto N, Sun-Wada GH, Wada Y.
Role of the Cytosolic Domain of the a3 Subunit of V-ATPase in the Interaction with Rab7 and Secretory Lysosome Trafficking in Osteoclasts
Biol Pharm Bull
2024
47(1):339-344
PubMed ID: 38296463
DOI: 10.1248/bpb.b23-00833
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19818
Gong L, Voon DC, Nakayama J, Takahashi C, Kohno S.
RB1 loss induces quiescent state through downregulation of RAS signaling in mammary epithelial cells
Cancer Sci
2024
Mar 11
PubMed ID: 38468443
DOI: 10.1111/cas.16122
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21591
Katayama M, Murakami S, Ishida H, Matsugo H, Sekine W, Ohira K, Takenaka-Uema A, Horimoto T.
Antigenic commonality and divergence of hemagglutinin-esterase-fusion protein among influenza D virus lineages revealed using epitope mapping.
J Virol
2024
e0190823
PubMed ID: 38345383
DOI: 10.1128/jvi.01908-23
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21592
Ito F, Yanatori I, Kato K, Toyokuni S.
Protocol for the isolation of GFP-expressing ferroptosis-dependent extracellular vesicles in in vitro cell culture models.
STAR Protoc
2024
5(1):102892
PubMed ID: 38363686
DOI: 10.1016/j.xpro.2024.102892
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21618
Kohyanagi N, Kitamura N, Ikeda S, Shibutani S, Sato K, Ohama T.
PP2A inhibitor SET promotes mTORC1 and Bmi1 signaling through Akt activation and maintains the colony-formation ability of cancer cells.
J Biol Chem
2024
300(1):105584
PubMed ID: 38141761
DOI: 10.1016/j.jbc.2023.105584
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21654
Kobayashi H, Shiba T, Yoshida T, Bolidong D, Kato K, Sato Y, Mochizuki M, Seto T, Kawashiri S, Hanayama R.
Precise analysis of single small extracellular vesicles using flow cytometry.
Sci Rep
2024
14(1):7465
PubMed ID: 38553534
DOI: 10.1038/s41598-024-57974-3
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21667
Kim YJ, Tohyama S, Nagashima T, Nagase M, Hida Y, Hamada S, Watabe AM, Ohtsuka T.
A light-controlled phospholipase C for imaging of lipid dynamics and controlling neural plasticity.
Cell Chem Biol
2024
PubMed ID: 38582083
DOI: 10.1016/j.chembiol.2024.03.001
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21674
Kinoshita S, Ishii M, Ando J, Kimura T, Yamaguchi T, Harada S, Takahashi F, Nakashima K, Nakazawa Y, Yamazaki S, Ohshima K, Takahashi K, Nakauchi H, Ando M.
Rejuvenated iPSC-derived GD2-directed CART Cells Harbor Robust Cytotoxicity Against Small Cell Lung Cancer.
Cancer Res Commun
2024
4(3):723-737
PubMed ID: 38380966
DOI: 10.1158/2767-9764.CRC-23-0259
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21699
Suzuki N, Konuma T, Ikegami T, Akashi S.
Biophysical insights into the dimer formation of human Sirtuin 2.
Protein Sci
2024
33(5):e4994
PubMed ID: 38647411
DOI: 10.1002/pro.4994
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21733
Fujii T, Liang L, Nakayama K, Katoh Y.
Defects in diffusion barrier function of ciliary transition zone caused by ciliopathy variations of TMEM218.
Hum Mol Genet
2024
PubMed ID: 38751342
DOI: 10.1093/hmg/ddae083
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21738
Otsuka Y, Imamura K, Oishi A, Asakawa K, Kondo T, Nakai R, Suga M, Inoue I, Sagara Y, Tsukita K, Teranaka K, Nishimura Y, Watanabe A, Umeyama K, Okushima N, Mitani K, Nagashima H, Kawakami K, Muguruma K, Tsujikawa A, Inoue H.
Phototoxicity avoidance is a potential therapeutic approach for retinal dystrophy caused by EYS dysfunction
JCI Insight
2024
9(8):e174179
PubMed ID: 38646933
DOI: 10.1172/jci.insight.174179
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21753
Tachibana K, Nakamura Y, Do TL, Kihara T, Kawada H, Yamamoto N, Ando K.
Mutations in the SARS-cov-2 spike proteins affected the ACE2-binding affinity during the development of omicron pandemic variants.
Biochem Biophys Res Commun
2024
719:150120
PubMed ID: 38759524
DOI: 10.1016/j.bbrc.2024.150120
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21781
Kitano M, Ohnishi H, Makino A, Miyamoto T, Hayashi Y, Mizuno K, Kaba S, Kawai Y, Kojima T, Kishimoto Y, Yamamoto N, Tomonaga K, Omori K.
An infection model for SARS-CoV-2 using rat transplanted with hiPSC-airway epithelial cells.
Tissue Eng Part A
2024
PubMed ID: 38832872
DOI: 10.1089/ten.TEA.2024.0016
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21812
Yu H, Kohno S, Voon DC, Hussein NH, Zhang Y, Nakayama J, Takegami Y, Takahashi C.
RECK/GPR124-driven WNT signaling in pancreatic and gastric cancer cells.
Cancer Sci
2024
PubMed ID: 38923741
DOI: 10.1111/cas.16258
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21871
Sugiyama Y, Okada S, Daigaku Y, Kusumoto E, Ito T.
Strategic targeting of Cas9 nickase induces large segmental duplications.
Cell Genom
2024
PubMed ID: 39053455
DOI: 10.1016/j.xgen.2024.100610
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21913
Ueno K, Kurazumi H, Suzuki R, Yanagihara M, Mizoguchi T, Harada T, Morikage N, Hamano K.
miR-709 exerts an angiogenic effect through a FGF2 upregulation induced by a GSK3B downregulation
Sci Rep
2024
14(1):11372
PubMed ID: 38762650
DOI: 10.1038/s41598-024-62340-4
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21920
Sekine W, Kamiki H, Ishida H, Matsugo H, Ohira K, Li K, Katayama M, Takenaka-Uema A, Murakami S, Horimoto T.
Adaptation potential of H3N8 canine influenza virus in human respiratory cells.
Sci Rep
2024
14(1):18750
PubMed ID: 39138310
DOI: 10.1038/s41598-024-69509-x
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21932
Miyahara S, Ohuchi M, Nomura M, Hashimoto E, Soga T, Saito R, Hayashi K, Sato T, Saito M, Yamashita Y, Shimada M, Yaegashi N, Yamada H, Tanuma N.
FDX2, an iron-sulfur cluster assembly factor, is essential to prevent cellular senescence, apoptosis or ferroptosis of ovarian cancer cells.
J Biol Chem
2024
107678
PubMed ID: 39151727
DOI: 10.1016/j.jbc.2024.107678
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21934
Tabata K, Kobayashi S, Itakura Y, Gonzalez G, Kabamba CF, Saito S, Sasaki M, Hall WW, Sawa H, Orba Y.
Increased production of orthoflavivirus single-round infectious particles produced in mammalian cells at a suboptimal culture temperature of 28°C.
J Virol Methods
2024
115007
PubMed ID: 39154937
DOI: 10.1016/j.jviromet.2024.115007
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21935
Wang Y, Moh-Moh-Aung A, Wang T, Fujisawa M, Ohara T, Yamamoto KI, Sakaguchi M, Yoshimura T, Matsukawa A.
Exosomal delivery of miR-200b-3p suppresses the growth of hepatocellular carcinoma cells by targeting ERG- and VEGF-mediated angiogenesis.
Gene
2024
148874
PubMed ID: 39159792
DOI: 10.1016/j.gene.2024.148874
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21952
Chiu CT, Tsai HH, Chen JY, Hu CJ, Chen HW.
An Immunoreceptor-Targeting Strategy with Minimalistic C3b Peptide Fusion Enhances SARS-CoV-2 RBD mRNA Vaccine Immunogenicity.
Int J Nanomedicine
2024
19:7201-7214
PubMed ID: 39050877
DOI: 10.2147/IJN.S463546
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21956
Ueno M, Sugiyama H, Li F, Nishimura T, Arakawa H, Chen X, Cheng X, Takeuchi S, Takeshita Y, Takamura T, Miyagi S, Toyama T, Soga T, Masuo Y, Kato Y, Nakamura H, Tsujiguchi H, Hara A, Tajima A, Noguchi-Shinohara M, Ono K, Kurayoshi K, Kobayashi M, Tadokoro Y, Kasahara A, Shoulkamy MI, Maeda K, Ogoshi T, Hirao A.
A Supramolecular Biosensor for Rapid and High-Throughput Quantification of a Disease-Associated Niacin Metabolite.
Anal Chem
2024
PubMed ID: 39183562
DOI: 10.1021/acs.analchem.4c02653
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21967
Okada M, Yamasaki S, Nakazato H, Hirahara Y, Ishibashi T, Kawamura M, Shimizu K, Fujii SI.
ARID1A-Deficient Tumors Acquire Immunogenic Neoantigens during the Development of Resistance to Targeted Therapy.
Cancer Res
2024
84(17):2792-2805
PubMed ID: 39228255
DOI: 10.1158/0008-5472.CAN-23-2846
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21975
Koike T, Sato T, Oe S, Hayashi S, Seki-Omura R, Nakano Y, Iwashita H, Sato Y, Hirahara Y, Kitada M.
CD34 distribution in C-fiber low threshold mechanoreceptors in the mouse dorsal root ganglion and spinal cord.
Brain Res
2024
1846:149227
PubMed ID: 39255903
DOI: 10.1016/j.brainres.2024.149227
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21979
Mori S, Kohyama M, Yasumizu Y, Tada A, Tanzawa K, Shishido T, Kishida K, Jin H, Nishide M, Kawada S, Motooka D, Okuzaki D, Naito R, Nakai W, Kanda T, Murata T, Terao C, Ohmura K, Arase N, Kurosaki T, Fujimoto M, Suenaga T, Kumanogoh A, Sakaguchi S, Ogawa Y, Arase H.
Neoself-antigens are the primary target for autoreactive T cells in human lupus.
Cell
2024
PubMed ID: 39276775
DOI: 10.1016/j.cell.2024.08.025
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21993
Kashiwagi M, Beck G, Kanuka M, Arai Y, Tanaka K, Tatsuzawa C, Koga Y, Saito YC, Takagi M, Oishi Y, Sakaguchi M, Baba K, Ikuno M, Yamakado H, Takahashi R, Yanagisawa M, Murayama S, Sakurai T, Sakai K, Nakagawa Y, Watanabe M, Mochizuki H, Hayashi Y.
A pontine-medullary loop crucial for REM sleep and its deficit in Parkinson's disease.
Cell
2024
PubMed ID: 39303715
DOI: 10.1016/j.cell.2024.08.046
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22065
Nagai N, Shioiri T, Hatano S, Sugiura N, Watanabe H.
Regulatory role of Heparan sulfate in leptin signaling.
Cell Signal
2024
124:111456
PubMed ID: 39384005
DOI: 10.1016/j.cellsig.2024.111456
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22066
Saji T, Endo M, Okada Y, Minami Y, Nishita M.
KIF1C facilitates retrograde transport of lysosomes through Hook3 and dynein.
Commun Biol
2024
7(1):1305
PubMed ID: 39394274
DOI: 10.1038/s42003-024-07023-6
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22154
Matsuzaki Y, Fukai Y, Konno A, Hirai H.
Optimal different adeno-associated virus capsid/promoter combinations to target specific cell types in the common marmoset cerebral cortex.
Mol Ther Methods Clin Dev
2024
32(4):101337
PubMed ID: 39391837
DOI: 10.1016/j.omtm.2024.101337
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22165
Kanadome T, Hoshino N, Nagai T, Yagi T, Matsuda T.
Protocol to visualize trans-interaction of clustered protocadherin using cIPAD, a fluorescent indicator, in cultured human cells and mouse neurons.
STAR Protoc
2024
5(1):102844
PubMed ID: 38277267
DOI: 10.1016/j.xpro.2024.102844
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22176
Onishi A, Tsunekawa Y, Mandai M, Ishimaru A, Ohigashi Y, Sho J, Yasuda K, Suzuki K, Izpisua Belmonte JC, Matsuzaki F, Takahashi M.
Optimization of HITI-Mediated Gene Insertion for Rhodopsin and Peripherin-2 in Mouse Rod Photoreceptors: Targeting Dominant Retinitis Pigmentosa.
Invest Ophthalmol Vis Sci
2024
65(13):38
PubMed ID: 39556087
DOI: 10.1167/iovs.65.13.38
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22179
Sakaguchi M, Kinoshita R, Tomonobu N, Sakaguchi Y, Futami J, Yamauchi A, Murata H, Yamamoto KI, Takahashi T, Gohara Y, Ochi T, Jiang F, Komalasari NLGY, Chen Y, Ruma IMW, Sumardika IW, Zhou J, Honjo T, Kuribayashi F, Sagayama K, Toyooka S, Kondo E, Inoue Y.
Enhanced design of pCMViR-TSC plasmid vector for sustainably high cargo gene expression in mammalian cells.
In Vitro Cell Dev Biol Anim
2024
PubMed ID: 39570532
DOI: 10.1007/s11626-024-00992-2
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22201
Yamashita M, Ogawa C, Zhang B, Kobayashi T, Nomura A, Barker C, Zou C, Yamanaka S, Hayashi KI, Shinkai Y, Moro K, Fargarasan S, Imami K, Seita J, Shirai F, Sawasaki T, Kanemaki MT, Taniuchi I.
Cell-type specific, inducible and acute degradation of targeted protein in mice by two degron systems.
Nat Commun
2024
15(1):10129
PubMed ID: 39613744
DOI: 10.1038/s41467-024-54308-9
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22234
Chida-Nagai A, Akagawa H, Sawai S, Ma YJ, Yakuwa S, Muneuchi J, Yasuda K, Yamazawa H, Yamamoto T, Takakuwa E, Tomaru U, Furutani Y, Kato T, Harada G, Inai K, Nakanishi T, Manabe A, Takeda A, Jing ZC.
Identification of Prostaglandin I2 Synthase Rare Variants in Patients With Williams Syndrome and Severe Peripheral Pulmonary Stenosis
J Am Heart Assoc
2024
13(9):e032872
PubMed ID: 38639351
DOI: 10.1161/JAHA.123.032872
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22235
Shinoda S, Sakai Y, Matsui T, Uematsu M, Koyama-Honda I, Sakamaki JI, Yamamoto H, Mizushima N.
Syntaxin 17 recruitment to mature autophagosomes is temporally regulated by PI4P accumulation
Elife
2024
12:RP92189
PubMed ID: 38831696
DOI: 10.7554/eLife.92189
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22236
Lin N, Miyamoto K, Ogawara T, Sakurai S, Kizaka-Kondoh S, Kadonosono T.
Epitope binning for multiple antibodies simultaneously using mammalian cell display and DNA sequencing
Commun Biol
2024
7(1):652
PubMed ID: 38806676
DOI: 10.1038/s42003-024-06363-7
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22237
Mubuchi A, Takechi M, Nishio S, Matsuda T, Itoh Y, Sato C, Kitajima K, Kitagawa H, Miyata S.
Assembly of neuron- and radial glial-cell-derived extracellular matrix molecules promotes radial migration of developing cortical neurons
Elife
2024
12:RP92342
PubMed ID: 38512724
DOI: 10.7554/eLife.92342
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22238
Takeshita M, Suzuki K, Nakazawa M, Kamata H, Ishii M, Oyamada Y, Oshima H, Usuda S, Tsunoda K, Takeuchi T.
Disease-specific autoantibody production in the lungs and salivary glands of anti-synthetase syndrome
Front Immunol
2024
15:1265792
PubMed ID: 38938569
DOI: 10.3389/fimmu.2024.1265792
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22241
Tanaka R, Sugiura K, Osabe K, Hattori M, Nagai T.
Genetically encoded bioluminescent glucose indicator for biological research.
Biochem Biophys Res Commun
2024
742:151092
PubMed ID: 39626367
DOI: 10.1016/j.bbrc.2024.151092
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22251
Hirabayashi Y, Lewis TL Jr, Du Y, Virga DM, Decker AM, Coceano G, Alvelid J, Paul MA, Hamilton S, Kneis P, Takahashi Y, Gaublomme JT, Testa I, Polleux F.
Most axonal mitochondria in cortical pyramidal neurons lack mitochondrial DNA and consume ATP
bioRxiv
2024
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PubMed ID: 38405915
DOI: 10.1101/2024.02.12.579972
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22285
Varner LR, Chaya T, Maeda Y, Tsutsumi R, Zhou S, Tsujii T, Okuzaki D, Furukawa T.
The deubiquitinase Otud7b suppresses cone photoreceptor degeneration in mouse models of retinal degenerative diseases
iScience
2024
27(4):109380
PubMed ID: 38510130
DOI: 10.1016/j.isci.2024.109380
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22311
Takada S, Gallo S, Silva S, Tanaka H, Pincheira O, Zúñiga J, Villarroel M, Hidalgo X, Melo-Tanner J, Suzuki H, Machida S, Takahashi H, Miyake N.
A Novel AGR2 Variant Causing Aberrant Monomer-Dimer Equilibrium Leading to Severe Respiratory and Digestive Symptoms
J Clin Immunol
2024
45(1):55
PubMed ID: 39673647
DOI: 10.1007/s10875-024-01847-x
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22320
Jiang F, Chen Y, Tomonobu N, Kinoshita R, Komalasari NLGY, Kasano-Camones CI, Ninomiya K, Murata H, Yamamoto KI, Gohara Y, Ochi T, Ruma IMW, Sumardika IW, Zhou J, Honjo T, Sakaguchi Y, Yamauchi A, Kuribayashi F, Futami J, Kondo E, Inoue Y, Toyooka S, Sakaguchi M.
Dissection of the signal transduction machinery responsible for the lysyl oxidase-like 4-mediated increase in invasive motility in triple-negative breast cancer cells: mechanistic insight into the integrin-β1-NF-κB-MMP9 axis
Front Oncol
2024
14:1371307.
PubMed ID: 38863623
DOI: 10.3389/fonc.2024.1371307
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22347
Mori K, Suzuki T, Waki U, Hayashi S, Kadono S, Kawahara R, Takeuchi M, Mizuta H, Dohmae N, Katayama R, Simizu S.
Identification of C-mannosylation in a receptor tyrosine kinase AXL
Glycobiology
2024
34(11):cwae096
PubMed ID: 39660536
DOI: 10.1093/glycob/cwae096
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22348
Yamazaki S, Fujii T, Chiba S, Shin HW, Nakayama K, Katoh Y.
TXNDC15, an ER-localized thioredoxin-like transmembrane protein, contributes to ciliary transition zone integrity.
J Cell Sci
2024
PubMed ID: 39679447
DOI: 10.1242/jcs.262123
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22378
Moe Iwata, Ryoko Kawabata, Nao Morimoto, Ryosuke F. Takeuchi, Takemasa Sakaguchi, Takashi Irie, Fumitaka Osakada
Evolutionary engineering and characterization of Sendai virus mutants capable of persistent infection and autonomous production
Frontiers in Virology
2024
4
DOI: 10.3389/fviro.2024.1363092
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22465
Sadhu S, Goswami S, Khatri R, Lohiya B, Singh V, Yadav R, Das V, Tripathy MR, Dwivedi P, Srivastava M, Mani S, Asthana S, Samal S, Awasthi A.
Berbamine prevents SARS-CoV-2 entry and transmission.
iScience
2024
27(12):111347
PubMed ID: 39640591
DOI: 10.1016/j.isci.2024.111347
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22602
Zhang Z, Isaji T, Oyama Y, Liu J, Xu Z, Sun Y, Fukuda T, Lu H, Gu J.
O-GlcNAcylation of Focal Adhesion Kinase Regulates Cell Adhesion, Migration, and Proliferation via the FAK/AKT Pathway
Biomolecules
2024
14(12):1577.
PubMed ID: 39766284
DOI: 10.3390/biom14121577
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22603
Yang Z, Yoshii SR, Sakai Y, Zhang J, Chino H, Knorr RL, Mizushima N.
Autophagy adaptors mediate Parkin-dependent mitophagy by forming sheet-like liquid condensates
EMBO J
2024
43(22):5613-5634
PubMed ID: 39420095
DOI: 10.1038/s44318-024-00272-5
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22684
Osumi R, Sugihara K, Yoshimoto M, Tokumura K, Tanaka Y, Hinoi E.
Role of proteoglycan synthesis genes in osteosarcoma stem cells
Front Oncol
2024
14:1325794
PubMed ID: 38690160
DOI: 10.3389/fonc.2024.1325794
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22694
Morikawa K, Nishida H, Imami K, Ishihama Y.
One-step N-Terminomics Based on Isolation of Protein N-Terminal Peptides From LysargiNase Digests by Tip-Based Strong Cation Exchange Chromatography
Mol Cell Proteomics
2024
23(9):100820
PubMed ID: 39069075
DOI: 10.1016/j.mcpro.2024.100820
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22719
Kunitake K, Mizuno T, Hattori K, Oneyama C, Kamiya M, Ota S, Urano Y, Kojima R.
Barcoding of small extracellular vesicles with CRISPR-gRNA enables comprehensive, subpopulation-specific analysis of their biogenesis and release regulators
Nat Commun
2024
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Organelle landscape analysis using a multiparametric particle-based method
PLoS Biol
2024
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Sugiyama K, Shimano H, Takahashi M, Shimura Y, Shimura A, Furuya T, Tomabechi R, Shirasaka Y, Higuchi K, Kishimoto H, Inoue K.
The Use of Carboxyfluorescein Reveals the Transport Function of MCT6/SLC16A5 Associated with CD147 as a Chloride-Sensitive Organic Anion Transporter in Mammalian Cells
J Pharm Sci
2024
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Arai Y, Yamanaka I, Okamoto T, Isobe A, Nakai N, Kamimura N, Suzuki T, Daidoji T, Ono T, Nakaya T, Matsumoto K, Okuzaki D, Watanabe Y.
Stimulation of interferon-β responses by aberrant SARS-CoV-2 small viral RNAs acting as retinoic acid-inducible gene-I agonists
iScience
2023
26(1):105742
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17804
Toshiki Takahashi, Jun Shirai, Miyo Matsuda, Sae Nakanaga, Shin Matsushita, Kei Wakita, Mizuki Hayashishita, Rigel Suzuki, Aya Noguchi, Naoto Yokota, and Hiroyuki Kawahara
Protein quality control machinery supports primary ciliogenesis by eliminating GDP-bound Rab8- family GTPases
iScience
2023
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Nakajima M, Kawahara R, Simizu S.
Cofilin promotes vasculogenic mimicry by regulating the actin cytoskeleton in human breast cancer cells
FEBS Lett
2023
597(8):1114-1124
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Gohara Y, Tomonobu N, Kinoshita R, Futami J, Audebert L, Chen Y, Komalasari NLGY, Jiang F, Yoshizawa C, Murata H, Yamamoto KI, Watanabe M, Kumon H, Sakaguchi M.
Novel extracellular role of REIC/Dkk-3 protein in PD-L1 regulation in cancer cells
J Mol Med (Berl)
2023
101(4):431-447
PubMed ID: 36869893
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18106
Komalasari NLGY, Tomonobu N, Kinoshita R, Chen Y, Sakaguchi Y, Gohara Y, Jiang F, Yamamoto KI, Murata H, Ruma IMW, Sumardika IW, Zhou J, Yamauchi A, Kuribayashi F, Inoue Y, Toyooka S, Sakaguchi M.
Lysyl oxidase-like 4 exerts an atypical role in breast cancer progression that is dependent on the enzymatic activity that targets the cell-surface annexin A2
Front Oncol
2023
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18139
Hoshino N, Kanadome T, Takasugi T, Itoh M, Kaneko R, Inoue YU, Inoue T, Hirabayashi T, Watanabe M, Matsuda T, Nagai T, Tarusawa E, Yagi T.
Visualization of trans homophilic interaction of clustered protocadherin in neurons
Proc Natl Acad Sci U S A
2023
120(38):e2301003120
PubMed ID: 37695902
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Kikuchi M, Takase S, Konuma T, Noritsugu K, Sekine S, Ikegami T, Ito A, Umehara T.
GAS41 promotes H2A.Z deposition through recognition of the N terminus of histone H3 by the YEATS domain
Proc Natl Acad Sci U S A
2023
120(43):e2304103120
PubMed ID: 37844223
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19540
Furukawa Y, Ishii M, Ando J, Ikeda K, Igarashi KJ, Kinoshita S, Azusawa Y, Toyota T, Honda T, Nakanishi M, Ohshima K, Masuda A, Yoshida E, Kitade M, Porteus M, Terao Y, Nakauchi H, Ando M.
iPSC-derived hypoimmunogenic tissue resident memory T cells mediate robust anti-tumor activity against cervical cancer
Cell Rep Med
2023
4(12):101327
PubMed ID: 38091985
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19549
Uemura K, Nobori H, Sato A, Toba S, Kusakabe S, Sasaki M, Tabata K, Matsuno K, Maeda N, Ito S, Tanaka M, Anraku Y, Kita S, Ishii M, Kanamitsu K, Orba Y, Matsuura Y, Hall WW, Sawa H, Kida H, Matsuda A, Maenaka K.
2-thiouridine is a broad-spectrum antiviral nucleoside analogue against positive-strand RNA viruses
Proc Natl Acad Sci U S A
2023
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Hatanaka A, Nakada S, Matsumoto G, Satoh K, Aketa I, Watanabe A, Hirakawa T, Tsujita T, Waku T, Kobayashi A.
The transcription factor NRF1 (NFE2L1) activates aggrephagy by inducing p62 and GABARAPL1 after proteasome inhibition to maintain proteostasis
Sci Rep
2023
13(1):14405
PubMed ID: 37658135
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19624
Park G, Fukasawa K, Horie T, Masuo Y, Inaba Y, Tatsuno T, Yamada T, Tokumura K, Iwahashi S, Iezaki T, Kaneda K, Kato Y, Ishigaki Y, Mieda M, Tanaka T, Ogawa K, Ochi H, Sato S, Shi YB, Inoue H, Lee H, Hinoi E.
l-Type amino acid transporter 1 in hypothalamic neurons in mice maintains energy and bone homeostasis
JCI Insight
2023
8(7):e154925
PubMed ID: 36862514
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19632
ukasawa K, Lyu J, Kubo T, Tanaka Y, Suzuki A, Horie T, Tomizawa A, Osumi R, Iwahashi S, Tokumura K, Murata M, Kobayashi M, Todo T, Hirao A, Hinoi E.
MEK5-ERK5 Axis Promotes Self-renewal and Tumorigenicity of Glioma Stem Cells
Cancer Res Commun
2023
3(1):148-159
PubMed ID: 36968222
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19650
Zhang S, Tsuji H, Jin H, Kitagori K, Akizuki S, Nakashima R, Yoshifuji H, Tanaka M, Arase H, Ohmura K, Morinobu A.
Rheumatoid factor recognizes specific domains of the IgG heavy chain complexed with HLA class II molecules
Rheumatology (Oxford)
2023
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PubMed ID: 36645239
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19789
Hagkarim NC, Hajkarim MC, Suzuki T, Fujiwara T, Winkler GS, Stewart GS, Grand RJ.
Disruption of the Mammalian Ccr4-Not Complex Contributes to Transcription-Mediated Genome Instability
Cells
2023
12(14):1868
PubMed ID: 37508532
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19919
Wuputra K, Tsai MH, Kato K, Ku CC, Pan JB, Yang YH, Saito S, Wu CC, Lin YC, Cheng KH, Kuo KK, Noguchi M, Nakamura Y, Yoshioka T, Wu DC, Lin CS, Yokoyama KK.
Jdp2 is a spatiotemporal transcriptional activator of the AhR via the Nrf2 gene battery
Inflamm Regen
2023
43(1):42
PubMed ID: 37596694
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Hirabayashi D, Yamamoto KI, Maruyama A, Tomonobu N, Kinoshita R, Chen Y, Komalasari NLGY, Murata H, Gohara Y, Jiang F, Zhou J, Ruma IMW, Sumardika IW, Yamauchi A, Kuribayashi F, Toyooka S, Inoue Y, Sakaguchi M.
LOXL1 and LOXL4 are novel target genes of the Zn2+-bound form of ZEB1 and play a crucial role in the acceleration of invasive events in triple-negative breast cancer cells
Front Oncol
2023
13:1142886
PubMed ID: 36910659
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Mitamura R, Nakano M, Isono M, Kurosawa K, Fukami T, Nakajima M.
NEAT1_2 and DAZAP1, Paraspeckle Components, Interact with PXR to Negatively Regulate CYP3A4 Induction
Drug Metab Dispos
2023
51(10):1230-1237
PubMed ID: 37349114
DOI: 10.1124/dmd.122.001065
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20922
Sasaki M, Tabata K, Kishimoto M, Itakura Y, Kobayashi H, Ariizumi T, Uemura K, Toba S, Kusakabe S, Maruyama Y, Iida S, Nakajima N, Suzuki T, Yoshida S, Nobori H, Sanaki T, Kato T, Shishido T, Hall WW, Orba Y, Sato A, Sawa H.
S-217622, a SARS-CoV-2 main protease inhibitor, decreases viral load and ameliorates COVID-19 severity in hamsters.
Sci Transl Med
2023
15(679):eabq4064
PubMed ID: 36327352
DOI: 10.1126/scitranslmed.abq4064
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20993
Okamoto K, Kamikubo Y, Yamauchi K, Okamoto S, Takahashi M, Ishida Y, Koike M, Ikegaya Y, Sakurai T, Hioki H.
Specific AAV2/PHP.eB-mediated gene transduction of CA2 pyramidal cells via injection into the lateral ventricle.
Sci Rep
2023
13(1):323
PubMed ID: 36609635
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21011
Hiyamizu S, Qiu H, Vuolo L, Stevenson NL, Shak C, Heesom KJ, Hamada Y, Tsurumi Y, Chiba S, Katoh Y, Stephens DJ, Nakayama K.
Multiple interactions of the dynein-2 complex with the IFT-B complex are required for effective IFT.
J Cell Sci
2023
PubMed ID: 36632779
DOI: 10.1242/jcs.260462
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21015
Shoji H, Kitao K, Miyazawa T, Nakagawa S.
Potentially reduced fusogenicity of syncytin-2 in New World monkeys.
FEBS Open Bio
2023
PubMed ID: 36647789
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21065
Morihiro K, Osumi H, Morita S, Hattori T, Baba M, Harada N, Ohashi R, Okamoto A.
Oncolytic Hairpin DNA Pair: Selective Cytotoxic Inducer through MicroRNA-Triggered DNA Self-Assembly.
J Am Chem Soc
2023
145(1):135-142
PubMed ID: 36538570
DOI: 10.1021/jacs.2c08974
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21076
Sato M, Maishi N, Hida Y, Yanagawa-Matsuda A, Alam MT, Sakakibara-Konishi J, Nam JM, Onodera Y, Konno S, Hida K.
Angiogenic inhibitor pre-administration improves the therapeutic effects of immunotherapy.
Cancer Med
2023
PubMed ID: 36808261
DOI: 10.1002/cam4.5696
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21092
Yoshimoto S, Suzuki T, Otani N, Takahashi D, Toshima K, Dohmae N, Simizu S.
Destabilization of vitelline membrane outer layer protein 1 homolog (VMO1) by C-mannosylation.
FEBS Open Bio
2023
PubMed ID: 36680395
DOI: 10.1002/2211-5463.13561
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21101
Ota A, Morita H, Naganuma T, Miyamoto M, Jojima K, Nojiri K, Matsuda J, Kihara A.
Bifunctional DEGS2 has higher hydroxylase activity toward substrates with very-long-chain fatty acids in the production of phytosphingosine-ceramides.
J Biol Chem
2023
104603
PubMed ID: 36907437
DOI: 10.1016/j.jbc.2023.104603
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17485
Tanikawa S, Ebisu Y, Sedlačík T, Semba S, Nonoyama T, Kurokawa T, Hirota A, Takahashi T, Yamaguchi K, Imajo M, Kato H, Nishimura T, Tanei ZI, Tsuda M, Nemoto T, Gong JP, Tanaka S.
Engineering of an electrically charged hydrogel implanted into a traumatic brain injury model for stepwise neuronal tissue reconstruction
Sci Rep
2023
13(1):2233
PubMed ID: 36788295
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21104
Kawano T, Kashiwagi M, Kanuka M, Chen CK, Yasugaki S, Hatori S, Miyazaki S, Tanaka K, Fujita H, Nakajima T, Yanagisawa M, Nakagawa Y, Hayashi Y.
ER proteostasis regulators cell-non-autonomously control sleep.
Cell Rep
2023
42(3):112267
PubMed ID: 36924492
DOI: 10.1016/j.celrep.2023.112267
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21158
Tao F, Kitamura K, Hanada S, Sugimoto K, Furihata T, Kojima N.
Rapid and Stable Formation Method of Human Astrocyte Spheroid in a High Viscous Methylcellulose Medium and Its Functional Advantages.
Bioengineering (Basel)
2023
10(3)
PubMed ID: 36978740
DOI: 10.3390/bioengineering10030349
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21159
Watanabe T, Narahari A, Bhardwaj E, Kuriyama K, Nishimura M, Izumi T, Fujimuro M, Ohno S.
Conserved cysteine residues in Kaposi's sarcoma herpesvirus ORF34 are necessary for viral production and viral pre-initiation complex formation.
bioRxiv
2023
PubMed ID: 36945456
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21179
Noritsugu K, Suzuki T, Dodo K, Ohgane K, Ichikawa Y, Koike K, Morita S, Umehara T, Ogawa K, Sodeoka M, Dohmae N, Yoshida M, Ito A.
Lysine long-chain fatty acylation regulates the TEAD transcription factor.
Cell Rep
2023
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PubMed ID: 37060904
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21219
Jojima K, Kihara A.
Metabolism of sphingadiene and characterization of the sphingadiene-producing enzyme FADS3.
Biochim Biophys Acta Mol Cell Biol Lipids
2023
1868(8):159335
PubMed ID: 37209771
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21222
Takahashi T, Shirai J, Matsuda M, Nakanaga S, Matsushita S, Wakita K, Hayashishita M, Suzuki R, Noguchi A, Yokota N, Kawahara H.
Protein quality control machinery supports primary ciliogenesis by eliminating GDP-bound Rab8-family GTPases.
iScience
2023
26(5):106652
PubMed ID: 37182096
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21248
Kasuga Y, Ouda R, Watanabe M, Sun X, Kimura M, Hatakeyama S, Kobayashi KS.
FBXO11 constitutes a major negative regulator of MHC class II through ubiquitin-dependent proteasomal degradation of CIITA.
Proc Natl Acad Sci U S A
2023
120(24):e2218955120
PubMed ID: 37279268
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21258
Nishi K, Yoshii A, Abell L, Zhou B, Frausto R, Ritterhoff J, McMillen TS, Sweet I, Wang Y, Gao C, Tian R.
Branched-chain keto acids inhibit mitochondrial pyruvate carrier and suppress gluconeogenesis in hepatocytes.
Cell Rep
2023
42(6):112641
PubMed ID: 37310861
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21261
Hiyamizu S, Qiu H, Tsurumi Y, Hamada Y, Katoh Y, Nakayama K.
Dynein-2-driven intraciliary retrograde trafficking indirectly requires multiple interactions of IFT54 in the IFT-B complex with the dynein-2 complex.
Biol Open
2023
PubMed ID: 37309605
DOI: 10.1242/bio.059976
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21265
Shimohata A, Rai D, Akagi T, Usui S, Ogiwara I, Kaneda M.
The intracellular C-terminal domain of mGluR6 contains ER retention motifs.
Mol Cell Neurosci
2023
103875
PubMed ID: 37352898
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21270
Yamaguchi S, Kamino M, Hamamura M, Otsuguro KI.
The cytosolic N-terminal region of heterologously-expressed transmembrane channel-like protein 1 (TMC1) can be cleaved in HEK293 cells.
PLoS One
2023
18(6):e0287249
PubMed ID: 37352201
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21278
Okada M, Shimizu K, Nakazato H, Yamasaki S, Fujii SI.
Detection of mutant antigen-specific T cell receptors against multiple myeloma for T cell engineering.
Mol Ther Methods Clin Dev
2023
29:541-555
PubMed ID: 37359417
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21285
Morishita K, Kondo J, Sakon D, Hayashibara A, Tamura I, Shimizu K, Takamatsu S, Murata K, Kamada Y, Miyoshi E.
Prohaptoglobin is a possible prognostic biomarker for colorectal cancer.
Biochem Biophys Res Commun
2023
672:72-80
PubMed ID: 37343317
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21309
Tanaka Y, Morozumi A, Hirokawa N.
Nodal flow transfers polycystin to determine mouse left-right asymmetry.
Dev Cell
2023
PubMed ID: 37413993
DOI: 10.1016/j.devcel.2023.06.002
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21312
Omata K, Nomura I, Hirata A, Yonezuka Y, Muto H, Kuriki R, Jimbo K, Ogasa K, Kato T.
Isolation and evaluation of erythroid progenitors in the livers of larval, froglet, and adult Xenopus tropicalis.
Biol Open
2023
PubMed ID: 37421150
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21316
Matsuura-Suzuki E, Toh H, Iwasaki S.
Human-rabbit Hybrid Translation System to Explore the Function of Modified Ribosomes.
Bio Protoc
2023
13(13):e4714
PubMed ID: 37456340
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21317
Tokuma H, Sakano D, Tanabe K, Tanizawa Y, Shiraki N, Kume S.
Selective proteasome degradation of C-terminally-truncated human WFS1 in pancreatic beta cells.
FEBS Open Bio
2023
PubMed ID: 37440664
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21326
Takahashi G, Miyaoka Y.
Large-scale single-cell cloning of genome-edited cultured human cells by On-chip SPiS.
STAR Protoc
2023
4(3):102364
PubMed ID: 37329509
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21335
Goto M, Nishimura G, Sato H, Yamaguchi Y, Morimoto N, Hashimoto H, Takahashi N.
Pharmacological profile of upacicalcet, a novel positive allosteric modulator of calcium-sensing receptor, in vitro and in vivo.
Eur J Pharmacol
2023
175936
PubMed ID: 37541363
DOI: 10.1016/j.ejphar.2023.175936
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21345
Komuro H, Shinohara S, Fukushima Y, Demachi-Okamura A, Muraoka D, Masago K, Matsui T, Sugita Y, Takahashi Y, Nishida R, Takashima C, Ohki T, Shigematsu Y, Watanabe F, Adachi K, Fukuyama T, Hamana H, Kishi H, Miura D, Tanaka Y, Onoue K, Onoguchi K, Yamashita Y, Stratford R, Clancy T, Yamaguchi R, Kuroda H, Doi K, Iwata H, Matsushita H.
Single-cell sequencing on CD8+ TILs revealed the nature of exhausted T cells recognizing neoantigen and cancer/testis antigen in non-small cell lung cancer.
J Immunother Cancer
2023
11(8)
PubMed ID: 37544663
DOI: 10.1136/jitc-2023-007180
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21353
Kanadome T, Hoshino N, Nagai T, Yagi T, Matsuda T.
Visualization of trans-interactions of a protocadherin-α between processes originating from single neurons.
iScience
2023
26(7):107238
PubMed ID: 37534169
DOI: 10.1016/j.isci.2023.107238
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21367
Tsuji K, Kikuchi E, Takashima Y, Shoji T, Takahashi H, Ito S, Morinaga D, Kashima M, Maeda M, Kitai H, Kikuchi J, Sakakibara-Konishi J, Konno S.
Inhibition of non-homologous end joining mitigates paclitaxel resistance resulting from mitotic slippage in non-small cell lung cancer
Cell Cycle
2023
22(17):1854-1864
PubMed ID: 37592765
DOI: 10.1080/15384101.2023.2243761
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21373
Suzuki MM, Iijima K, Ogami K, Shinjo K, Murofushi Y, Xie J, Wang X, Kitano Y, Mamiya A, Kibe Y, Nishimura T, Ohka F, Saito R, Sato S, Kobayashi J, Yao R, Miyata K, Kataoka K, Suzuki HI, Kondo Y.
TUG1-mediated R-loop resolution at microsatellite loci as a prerequisite for cancer cell proliferation.
Nat Commun
2023
14(1):4521
PubMed ID: 37607907
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21382
Xu J, Hashino T, Tanaka R, Kawaguchi K, Yoshida H, Kataoka T.
The BCL-2 family protein BCL-RAMBO interacts and cooperates with GRP75 to promote its apoptosis signaling pathway.
Sci Rep
2023
13(1):14041
PubMed ID: 37640805
DOI: 10.1038/s41598-023-41196-0
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21398
Kanao E, Ishida K, Mizuta R, Li Y, Imami K, Tanigawa T, Sasaki Y, Akiyoshi K, Adachi J, Otsuka K, Ishihama Y, Kubo T.
Rapid and Highly Efficient Purification of Extracellular Vesicles Enabled by a TiO2 Hybridized Spongy-like Polymer.
Anal Chem
2023
PubMed ID: 37703188
DOI: 10.1021/acs.analchem.3c03411
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21416
Sogawa A, Komori R, Yanagitani K, Ohfurudono M, Tsuru A, Kadoi K, Kimata Y, Yoshida H, Kohno K.
Signal sequence-triage is activated by translocon obstruction sensed by an ER stress sensor IRE1α.
Cell Struct Funct
2023
PubMed ID: 37766570
DOI: 10.1247/csf.23072
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21472
Takeuchi K, Tabe S, Takahashi K, Aoshima K, Matsuo M, Ueno Y, Furukawa Y, Yamaguchi K, Ohtsuka M, Morinaga S, Miyagi Y, Yamaguchi T, Tanimizu N, Taniguchi H.
Incorporation of human iPSC-derived stromal cells creates a pancreatic cancer organoid with heterogeneous cancer-associated fibroblasts.
Cell Rep
2023
42(11):113420
PubMed ID: 37955987
DOI: 10.1016/j.celrep.2023.113420
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21501
Nishida H, Kanao E, Ishihama Y.
Centrifugal Gel Crushing Tips for Gel-Based Proteome Analysis.
Anal Chem
2023
PubMed ID: 38055789
DOI: 10.1021/acs.analchem.3c02527
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21514
Nomura M, Ohuchi M, Sakamoto Y, Kudo K, Yaku K, Soga T, Sugiura Y, Morita M, Hayashi K, Miyahara S, Sato T, Yamashita Y, Ito S, Kikuchi N, Sato I, Saito R, Yaegashi N, Fukuhara T, Yamada H, Shima H, Nakayama KI, Hirao A, Kawasaki K, Arai Y, Akamatsu S, Tanuma SI, Sato T, Nakagawa T, Tanuma N.
Niacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma.
Nat Commun
2023
14(1):8095
PubMed ID: 38092728
DOI: 10.1038/s41467-023-43630-3
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21660
Agata A, Ohtsuka S, Noji R, Gotoh H, Ono K, Nomura T.
A Neanderthal/Denisovan GLI3 variant contributes to anatomical variations in mice.
Front Cell Dev Biol
2023
2:11:1247361.
PubMed ID: 38020913
DOI: 10.3389/fcell.2023.1247361
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21852
Mizuta H, Takakusaki A, Suzuki T, Otake K, Dohmae N, Simizu S.
C-mannosylation regulates stabilization of RAMP1 protein and RAMP1-mediated cell migration
FEBS J
2023
290(1):196-208
PubMed ID: 35942636
DOI: 10.1111/febs.16592
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22252
Murakami T, Ruengsinpinya L, Takahata Y, Nakaminami Y, Hata K, Nishimura R.
HOXA10 promotes Gdf5 expression in articular chondrocytes
Sci Rep
2023
13(1):22778
PubMed ID: 38123662
DOI: 10.1038/s41598-023-50318-7
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22253
Ohno Y, Nakamura T, Iwasaki T, Katsuyama A, Ichikawa S, Kihara A.
Determining the structure of protein-bound ceramides, essential lipids for skin barrier function
iScience
2023
26(11):108248
PubMed ID: 37965138
DOI: 10.1016/j.isci.2023.108248
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22254
Suga S, Nakamura K, Nakanishi Y, Humbel BM, Kawai H, Hirabayashi Y.
An interactive deep learning-based approach reveals mitochondrial cristae topologies
PLoS Biol
2023
21(8):e3002246
PubMed ID: 37651352
DOI: 10.1371/journal.pbio.3002246
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22255
Kitao K, Shoji H, Miyazawa T, Nakagawa S.
Dynamic Evolution of Retroviral Envelope Genes in Egg-Laying Mammalian Genomes
Mol Biol Evol
2023
40(5):msad090
PubMed ID: 37062963
DOI: 10.1093/molbev/msad090
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22588
Shima Y, Skibbe H, Sasagawa Y, Fujimori N, Iwayama Y, Isomura-Matoba A, Yano M, Ichikawa T, Nikaido I, Hattori N, Kato T.
Distinctiveness and continuity in transcriptome and connectivity in the anterior-posterior axis of the paraventricular nucleus of the thalamus
Cell Rep
2023
42(10):113309
PubMed ID: 37862168
DOI: 10.1016/j.celrep.2023.113309
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17502
Haraguchi-Suzuki K, Kawabata-Iwakawa R, Suzuki T, Suto T, Takazawa T, Saito S.
Local anesthetic lidocaine induces growth suppression of HeLa cells by decreasing and changing the cellular localization of the proliferation marker Ki-67
Genes Cells
2022
27(11):675-684
PubMed ID: 36074048
DOI: 10.1111/gtc.12983
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17510
Miku Akishino, Yuko Aoki, Hajime Baba, Makio Asakawa, Yoichiro Hama, Susumu Mitsutake
Red algae-derived isofloridoside activates the sweet taste receptor T1R2/T1R3
Food Bioscience
2022
50:102186
DOI: 10.1016/j.fbio.2022.102186
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17529
Tsukida K, Muramatsu SI, Osaka H, Yamagata T, Muramatsu K.
WDR45 variants cause ferrous iron loss due to impaired ferritinophagy associated with nuclear receptor coactivator 4 and WD repeat domain phosphoinositide interacting protein 4 reduction
Brain Commun
2022
4(6):fcac304
PubMed ID: 36751498
DOI: 10.1093/braincomms/fcac304
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17581
Kamiki H, Murakami S, Nishikaze T, Hiono T, Igarashi M, Furuse Y, Matsugo H, Ishida H, Katayama M, Sekine W, Muraki Y, Takahashi M, Takenaka-Uema A, Horimoto T.
Influenza A Virus Agnostic Receptor Tropism Revealed Using a Novel Biological System with Terminal Sialic Acid Knockout Cells
J Virol
2022
96(15):e0041622
PubMed ID: 35862707
DOI: 10.1128/jvi.00416-22
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17616
Yamashita F, Kaieda T, Shimomura T, Kawaguchi M, Lin CY, Johnson MD, Tanaka H, Kiwaki T, Fukushima T, Kataoka H.
Role of the polycystic kidney disease domain in matriptase chaperone activity and localization of hepatocyte growth factor activator inhibitor-1
FEBS J
2022
289(12):3422-3439
PubMed ID: 35020274
DOI: 10.1111/febs.16348
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17620
Saito S, Funayama K, Kato W, Okuda M, Kawamoto M, Matsubara T, Sato T, Sato A, Otsuguro S, Sasaki M, Orba Y, Sawa H, Maenaka K, Shindo K, Imoto M, Arai MA.
Dihydromaniwamycin E, a Heat-Shock Metabolite from Thermotolerant Streptomyces sp. JA74, Exhibiting Antiviral Activity against Influenza and SARS-CoV-2 Viruses
J Nat Prod
2022
85(11):2583-2591
PubMed ID: 36223390
DOI: 10.1021/acs.jnatprod.2c00550
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17651
Wei Z, Shimizu K, Sarii RS, Muthusinghe DS, Lokupathirage SMW, Nio-Kobayashi J, Yoshimatsu K.
Pathological Studies on Hantaan Virus-Infected Mice Simulating Severe Hemorrhagic Fever with Renal Syndrome
Viruses
2022
14(10):2247
PubMed ID: 36298802
DOI: 10.3390/v14102247
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17675
Yamauchi K, Okamoto S, Ishida Y, Konno K, Hoshino K, Furuta T, Takahashi M, Koike M, Isa K, Watanabe M, Isa T, Hioki H.
Fluorochromized tyramide-glucose oxidase as a multiplex fluorescent tyramide signal amplification system for histochemical analysis
Sci Rep
2022
12(1):14807
PubMed ID: 36097273
DOI: 10.1038/s41598-022-19085-9
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17714
Matsumura Y, To TK, Kunieda T, Kohno H, Kakutani T, Kubo T.
Mblk-1/E93, an ecdysone related-transcription factor, targets synaptic plasticity-related genes in the honey bee mushroom bodies
Sci Rep
2022
12(1):21367
PubMed ID: 36494426
DOI: 10.1038/s41598-022-23329-z
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17783
Ohshima T, Yamamoto H, Sakamaki Y, Saito C, Mizushima N.
NCOA4 drives ferritin phase separation to facilitate macroferritinophagy and microferritinophagy
J Cell Biol
2022
221(10):e202203102
PubMed ID: 36066504
DOI: 10.1083/jcb.202203102
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17788
Takeuchi Y, Ushimaru K, Kaneda K, Maruyama C, Ito T, Yamanaka K, Ogasawara Y, Katano H, Kato Y, Dairi T, Hamano Y.
First direct evidence for direct cell-membrane penetrations of polycationic homopoly(amino acid)s produced by bacteria
Commun Biol
2022
5(1):1132
PubMed ID: 36289442
DOI: 10.1038/s42003-022-04110-4
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19238
Suzuki T, Hoshina M, Nishijima S, Hoshina N, Kikuguchi C, Tomohiro T, Fukao A, Fujiwara T, Yamamoto T.
Regulation of CCR4-NOT complex deadenylase activity and cellular responses by MK2-dependent phosphorylation of CNOT2
RNA Biol
2022
19(1):234-246
PubMed ID: 35129087
DOI: 10.1080/15476286.2021.2021676
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19240
Narita M, Denk T, Matsuo Y, Sugiyama T, Kikuguchi C, Ito S, Sato N, Suzuki T, Hashimoto S, Machová I, Tesina P, Beckmann R, Inada T.
A distinct mammalian disome collision interface harbors K63-linked polyubiquitination of uS10 to trigger hRQT-mediated subunit dissociation
Nat Commun
2022
13(1):6411
PubMed ID: 36302773
DOI: 10.1038/s41467-022-34097-9
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20207
Tsuji H, Ohmura K, Jin H, Naito R, Arase N, Kohyama M, Suenaga T, Sakakibara S, Kochi Y, Okada Y, Yamamoto K, Kikutani H, Morinobu A, Mimori T, Arase H.
Anti-dsDNA antibodies recognize DNA presented on HLA class II molecules of systemic lupus erythematosus risk alleles.
Arthritis Rheumatol
2022
PubMed ID: 34164946
DOI: 10.1002/art.41897
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20452
Tanaka K, Kandori S, Sakka S, Nitta S, Tanuma K, Shiga M, Nagumo Y, Negoro H, Kojima T, Mathis BJ, Shimazui T, Watanabe M, Sato TA, Miyamoto T, Matsuzaka T, Shimano H, Nishiyama H.
ELOVL2 promotes cancer progression by inhibiting cell apoptosis in renal cell carcinoma.
Oncol Rep
2022
47(2)
PubMed ID: 34841437
DOI: 10.3892/or.2021.8234
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20477
Arase N, Tsuji H, Takamatsu H, Jin H, Konaka H, Hamaguchi Y, Tonomura K, Kotobuki Y, Ueda-Hayakawa I, Matsuoka S, Hirano T, Yorifuji H, Murota H, Ohmura K, Nakashima R, Sato T, Kumanogoh A, Katayama I, Arase H, Fujimoto M.
Cell surface-expressed Ro52/IgG/HLA-DR complex is targeted by autoantibodies in patients with inflammatory myopathies.
J Autoimmun
2022
126:102774
PubMed ID: 34896887
DOI: 10.1016/j.jaut.2021.102774
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20517
Qiu H, Tsurumi Y, Katoh Y, Nakayama K.
Combinations of deletion and missense variations of the dynein-2 DYNC2LI1 subunit found in skeletal ciliopathies cause ciliary defects.
Sci Rep
2022
12(1):31
PubMed ID: 34997029
DOI: 10.1038/s41598-021-03950-0
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20522
Hiraiwa M, Fukasawa K, Iezaki T, Sabit H, Horie T, Tokumura K, Iwahashi S, Murata M, Kobayashi M, Suzuki A, Park G, Kaneda K, Todo T, Hirao A, Nakada M, Hinoi E.
SMURF2 phosphorylation at Thr249 modifies glioma stemness and tumorigenicity by regulating TGF-β receptor stability.
Commun Biol
2022
5(1):22
PubMed ID: 35017630
DOI: 10.1038/s42003-021-02950-0
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20524
Nomura T, Nagao K, Shirai R, Gotoh H, Umeda M, Ono K.
Temperature sensitivity of Notch signaling underlies species-specific developmental plasticity and robustness in amniote brains.
Nat Commun
2022
13(1):96
PubMed ID: 35013223
DOI: 10.1038/s41467-021-27707-5
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16114
Wuputra K, Tsai MH, Kato K, Yang YH, Pan JB, Ku CC, Noguchi M, Kishikawa S, Nakade K, Chen HL, Liu CJ, Nakamura Y, Kuo KK, Lin YC, Chan TF, Wu DC, Hou MF, Huang SK, Lin CS, Yokoyama KK.
Dimethyl sulfoxide stimulates the AhR-Jdp2 axis to control ROS accumulation in mouse embryonic fibroblasts
Cell Biol Toxicol
2022
Mar 15
PubMed ID: 33723743
DOI: 10.1007/s10565-021-09592-2
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20588
Jin H, Kishida K, Arase N, Matsuoka S, Nakai W, Kohyama M, Suenaga T, Yamamoto K, Sasazuki T, Arase H.
Abrogation of self-tolerance by misfolded self-antigens complexed with MHC class II molecules.
Sci Adv
2022
8(9):eabj9867
PubMed ID: 35245125
DOI: 10.1126/sciadv.abj9867
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20597
Murakami Y, Masaki M, Miyazaki S, Oketani R, Hayashi Y, Yanagisawa M, Honjoh S, Kano H.
Spectroscopic second and third harmonic generation microscopy using a femtosecond laser source in the third near-infrared (NIR-III) optical window.
Biomed Opt Express
2022
13(2):694-708
PubMed ID: 35284173
DOI: 10.1364/BOE.446273
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20641
Miyajima Y, Noguchi S, Tanaka Y, Li JR, Nishimura H, Kishima M, Lim J, Furuhata E, Suzuki T, Kasukawa T, Suzuki H.
Prediction of transcription factors associated with DNA demethylation during human cellular development.
Chromosome Res
2022
30(1):109-121
PubMed ID: 35142952
DOI: 10.1007/s10577-022-09685-6
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20659
Chino H, Yamasaki A, Ode KL, Ueda HR, Noda NN, Mizushima N.
Phosphorylation by casein kinase 2 enhances the interaction between ER-phagy receptor TEX264 and ATG8 proteins.
EMBO Rep
2022
e54801
PubMed ID: 35417087
DOI: 10.15252/embr.202254801
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20702
Nashimoto Y, Matsushita F, Dijkstra JM, Nakamura Y, Akiyama H, Hamako J, Morita T, Araki S, Matsui T.
Bitiscetin-3, a Novel C-Type Lectin-like Protein Cloned from the Venom Gland of the Viper Bitis arietans, Induces Platelet Agglutination and Inhibits Binding of Von Willebrand Factor to Collagen.
Toxins (Basel)
2022
14(4)
PubMed ID: 35448845
DOI: 10.3390/toxins14040236
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20704
Kamo H, Kawahara R, Simizu S.
Tyrosinase suppresses vasculogenic mimicry in human melanoma cells.
Oncol Lett
2022
23(5):169
PubMed ID: 35496574
DOI: 10.3892/ol.2022.13289
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20713
Satoda Y, Noguchi T, Fujii T, Taniguchi A, Katoh Y, Nakayama K.
BROMI/TBC1D32 together with CCRK/CDK20 and FAM149B1/JBTS36 contributes to IFT turnaround involving ICK/CILK1.
Mol Biol Cell
2022
mbcE22030089
PubMed ID: 35609210
DOI: 10.1091/mbc.E22-03-0089
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16502
Kamada H, Yasuhira S, Shibazaki M, Amano H, Maesawa C.
DUSP4 Inactivation Leads to Reduced Extracellular Signal‒Regulated Kinase Activity through Upregulation of DUSP6 in Melanoma Cells
J Invest Dermatol
2022
S0022-202X(22)00126-9
PubMed ID: 35189148
DOI: 10.1016/j.jid.2022.02.007
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20724
Yasui R, Matsui A, Sekine K, Okamoto S, Taniguchi H.
Highly Sensitive Detection of Human Pluripotent Stem Cells by Loop-Mediated Isothermal Amplification.
Stem Cell Rev Rep
2022
PubMed ID: 35661077
DOI: 10.1007/s12015-022-10402-3
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20729
Ishida Y, Tasaki K, Katoh Y, Nakayama K.
Molecular basis underlying the ciliary defects caused by IFT52 variations found in skeletal ciliopathies.
Mol Biol Cell
2022
mbcE22050188
PubMed ID: 35704471
DOI: 10.1091/mbc.E22-05-0188
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16632
Hada M, Miura H, Tanigawa A, Matoba S, Inoue K, Ogonuki N, Hirose M, Watanabe N, Nakato R, Fujiki K, Hasegawa A, Sakashita A, Okae H, Miura K, Shikata D, Arima T, Shirahige K, Hiratani I, Ogura A.
Highly rigid H3.1/H3.2-H3K9me3 domains set a barrier for cell fate reprogramming in trophoblast stem cells
Genes Dev
2022
36(1-2):84-102
PubMed ID: 34992147
DOI: 10.1101/gad.348782.121
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16658
Sasaki K, Suzuki M, Sonoda T, Schneider-Poetsch T, Ito A, Takagi M, Fujishiro S, Sohtome Y, Dodo K, Umehara T, Aburatani H, Shin-Ya K, Nakao Y, Sodeoka M, Yoshida M.
Visualization of the dynamic interaction between nucleosomal histone H3K9 tri-methylation and HP1α chromodomain in living cells
Cell Chem Biol
2022
S2451-9456(22)00198-2
PubMed ID: 35728598
DOI: 10.1016/j.chembiol.2022.05.006
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16659
Matsuura-Suzuki E, Shimazu T, Takahashi M, Kotoshiba K, Suzuki T, Kashiwagi K, Sohtome Y, Akakabe M, Sodeoka M, Dohmae N, Ito T, Shinkai Y, Iwasaki S.
METTL18-mediated histidine methylation of RPL3 modulates translation elongation for proteostasis maintenance
Elife
2022
11:e72780
PubMed ID: 35674491
DOI: 10.7554/eLife.72780
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20750
Yamada T, Fukasawa K, Horie T, Kadota T, Lyu J, Tokumura K, Ochiai S, Iwahashi S, Suzuki A, Park G, Ueda R, Yamamoto M, Kitao T, Shirahase H, Ochi H, Sato S, Iezaki T, Hinoi E.
The role of CDK8 in mesenchymal stem cells in controlling osteoclastogenesis and bone homeostasis.
Stem Cell Reports
2022
PubMed ID: 35777359
DOI: 10.1016/j.stemcr.2022.06.001
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16732
Zhu Z, Kitano T, Morimatsu M, Tanaka A, Morioka R, Lin X, Orino K, Yoshikawa Y.
BRCA2 C-Terminal RAD51-Binding Domain Confers Resistance to DNA-Damaging Agents
Int J Mol Sci
2022
23(7):4060
PubMed ID: 35409418
DOI: 10.3390/ijms23074060
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16747
Fujii K, Morita S, Mochizuki M, Shibuya-Takahashi R, Fujimori H, Yamaguchi K, Abe J, Yamazaki T, Imai T, Sugamura K, Yasuda J, Satoh K, Sato I, Saito-Koyama R, Fujishima F, Sasano H, Kato Y, Matsuura K, Asada Y, Tamai K.
Establishment of a monoclonal antibody against glycosylated CD271 specific for cancer cells in immunohistochemistry
Cancer Sci . 2022 Mar 28
2022
Mar 28
PubMed ID: 35343032
DOI: 10.1111/cas.15340
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16748
Song W, Isaji T, Nakano M, Liang C, Fukuda T, Gu J.
O-GlcNAcylation regulates β1,4-GlcNAc-branched N-glycan biosynthesis via the OGT/SLC35A3/GnT-IV axis
FASEB J
2022
36(2):e22149
PubMed ID: 34981577
DOI: 10.1096/fj.202101520R
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16749
Kitanishi T, Tashiro M, Kitanishi N, Mizuseki K.
Intersectional, anterograde transsynaptic targeting of neurons receiving monosynaptic inputs from two upstream regions
Commun Biol
2022
5(1):149
PubMed ID: 35190665
DOI: 10.1038/s42003-022-03096-3
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16750
Otsuka K, Sawai-Ogawa M, Kihara A.
Formation of fatty alcohols-components of meibum lipids-by the fatty acyl-CoA reductase FAR2 is essential for dry eye prevention
FASEB J
2022
36(4):e22216
PubMed ID: 35238077
DOI: 10.1096/fj.202101733R
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16765
Takahashi S, Shibutani S, Iwata H.
Nuclear-targeted 4E-BP1 is dephosphorylated, induces nuclear translocation of eIF4E, and alters mRNA translation
Exp Cell Res
2022
418(1):113246
PubMed ID: 35697076
DOI: 10.1016/j.yexcr.2022.113246
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20788
Oishi T, Ito M, Koizumi S, Horikawa M, Yamamoto T, Yamagishi S, Yamasaki T, Sameshima T, Suzuki T, Sugimura H, Namba H, Kurozumi K.
Efficacy of HSV-TK/GCV system suicide gene therapy using SHED expressing modified HSV-TK against lung cancer brain metastases.
Mol Ther Methods Clin Dev
2022
26:253-265
PubMed ID: 35892087
DOI: 10.1016/j.omtm.2022.07.001
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20822
Deai M, Oya R, Saso N, Tanaka A, Uchida I, Miyake Y, Tachihara R, Otsugu M, Mine A, Sato K, Tomura H.
Ethylenediaminetetraacetic acid (EDTA) enhances cAMP production in human TDAG8-expressing cells.
Biochem Biophys Res Commun
2022
626:15-20
PubMed ID: 35964552
DOI: 10.1016/j.bbrc.2022.07.110
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17100
Izumi A, Yamamoto K, Kawaguchi M, Yamashita F, Fukushima T, Kiwaki T, Tanaka H, Yamashita Y, Kataoka H.
Insufficiency of hepatocyte growth factor activator inhibitor-1 confers lymphatic invasion of tongue carcinoma cells
Cancer Sci
2022
113(6):2179-2193
PubMed ID: 35332604
DOI: 10.1111/cas.15346
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20836
Kashio M, Masubuchi S, Tominaga M.
Protein kinase C (PKC)-mediated phosphorylation of TRPM2 Thr738 counteracts the effect of cytosolic Ca2+ and elevates the temperature threshold.
J Physiol
2022
PubMed ID: 36042566
DOI: 10.1113/JP283350
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20845
Zhou Z, Katoh Y, Nakayama K.
CEP19-RABL2-IFT-B axis controls BBSome-mediated ciliary GPCR export.
Mol Biol Cell
2022
PubMed ID: 36074075
DOI: 10.1091/mbc.E22-05-0161
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20857
Nohara T, Ohno Y, Kihara A.
Impaired production of skin barrier lipid acylceramides and abnormal localization of PNPLA1 due to ichthyosis-causing mutations in PNPLA1.
J Dermatol Sci
2022
107(2):89-94
PubMed ID: 35970721
DOI: 10.1016/j.jdermsci.2022.07.008
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20869
Lyu X, Imai S, Yamano T, Hanayama R.
Preventing SARS-CoV-2 Infection Using Anti-spike Nanobody-IFN-β Conjugated Exosomes.
Pharm Res
2022
PubMed ID: 36163411
DOI: 10.1007/s11095-022-03400-0
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20873
Yamamura N, Mikkaichi T, Itokawa KI, Hoshi M, Damme K, Geigner S, Baumhauer C.
Mirogabalin, a novel α2δ ligand, is not a substrate of LAT1, but of PEPT1, PEPT2, OAT1, OAT3, OCT2, MATE1 and MATE2-K.
Xenobiotica
2022
1-42
PubMed ID: 36170033
DOI: 10.1080/00498254.2022.2129517
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20880
Kanadome T, Hayashi K, Seto Y, Eiraku M, Nakajima K, Nagai T, Matsuda T.
Development of intensiometric indicators for visualizing N-cadherin interaction across cells.
Commun Biol
2022
5(1):1065
PubMed ID: 36207396
DOI: 10.1038/s42003-022-04023-2
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20892
Mang D, Mayu K, Toyama T, Yamagishi T, Sato R.
BmGr4 responds to sucrose and glucose and expresses in tachykinin-related peptide-secreting enteroendocrine cells.
Insect Biochem Mol Biol
2022
103858
PubMed ID: 36244651
DOI: 10.1016/j.ibmb.2022.103858
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20906
Nakazato A, Mochizuki M, Shibuya-Takahashi R, Fujimori H, Fujii K, Saijoh S, Morita S, Yamazaki T, Imai T, Sato I, Satoh K, Yamaguchi K, Sugamura K, Yasuda J, Matsuura K, Shojaku H, Asada Y, Tamai K.
RELA is required for CD271 expression and stem-like characteristics in hypopharyngeal cancer.
Sci Rep
2022
12(1):17751
PubMed ID: 36273237
DOI: 10.1038/s41598-022-22736-6
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20912
Kotani N, Nakano T, Kuwahara R.
Host cell membrane proteins located near SARS-CoV-2 spike protein attachment sites are identified using proximity labeling and proteomic analysis.
J Biol Chem
2022
298(11):102500
PubMed ID: 36152751
DOI: 10.1016/j.jbc.2022.102500
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20914
Wang TW, Johmura Y, Suzuki N, Omori S, Migita T, Yamaguchi K, Hatakeyama S, Yamazaki S, Shimizu E, Imoto S, Furukawa Y, Yoshimura A, Nakanishi M.
Blocking PD-L1-PD-1 improves senescence surveillance and ageing phenotypes.
Nature
2022
PubMed ID: 36323784
DOI: 10.1038/s41586-022-05388-4
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20926
Akiyama M, Unoki T, Aoki H, Nishimura A, Shinkai Y, Warabi E, Nishiyama K, Furumoto Y, Anzai N, Akaike T, Nishida M, Kumagai Y.
Cystine-dependent antiporters buffer against excess intracellular reactive sulfur species-induced stress.
Redox Biol
2022
57:102514
PubMed ID: 36279630
DOI: 10.1016/j.redox.2022.102514
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17337
Sekine W, Takenaka-Uema A, Kamiki H, Ishida H, Matsugo H, Murakami S, Horimoto T.
Adaptation of the H7N2 Feline Influenza Virus to Human Respiratory Cell Culture
Viruses
2022
14(5):1091
PubMed ID: 35632832
DOI: 10.3390/v14051091
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20971
Tatsumi A, Hirakochi H, Inoue S, Tanaka Y, Furuno H, Ikeda M, Ishibashi S, Taguchi T, Yamamoto K, Onishi I, Sachs Z, Largaespada DA, Kitagawa M, Kurata M.
Identification of NRAS Downstream Genes with CRISPR Activation Screening.
Biology (Basel)
2022
11(11)
PubMed ID: 36358254
DOI: 10.3390/biology11111551
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20975
Moriyama H, Moriyama M, Ozawa T, Tsuruta D, Hayakawa T.
Differentiation of Human Adipose-Derived Mesenchymal Stromal/Stem Cells into Insulin-Producing Cells with A Single Tet-Off Lentiviral Vector System.
Cell J
2022
24(12):705-714
PubMed ID: 36527342
DOI: 10.22074/cellj.2022.557533.1063
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20998
Ozono T, Kimura Y, Suenaga T, Beck G, Jinno J, Aguirre C, Ikenaka K, Krainc D, Mochizuki H, Arase H.
Extracellular transportation of α-synuclein by HLA class II molecules.
Biochem Biophys Res Commun
2022
644:25-33
PubMed ID: 36621149
DOI: 10.1016/j.bbrc.2022.12.082
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21033
Takahashi TM, Hirano A, Kanda T, Saito VM, Ashitomi H, Tanaka KZ, Yokoshiki Y, Masuda K, Yanagisawa M, Vogt KE, Tokuda T, Sakurai T.
Optogenetic induction of hibernation-like state with modified human Opsin4 in mice.
Cell Rep Methods
2022
2(11):100336
PubMed ID: 36452866
DOI: 10.1016/j.crmeth.2022.100336
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21037
Takahashi M, Kobayashi T, Mizuma H, Yamauchi K, Okamoto S, Okamoto K, Ishida Y, Koike M, Watanabe M, Isa T, Hioki H.
Preferential arborization of dendrites and axons of parvalbumin- and somatostatin-positive GABAergic neurons within subregions of the mouse claustrum.
Neurosci Res
2022
PubMed ID: 36574563
DOI: 10.1016/j.neures.2022.11.008
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17361
Hirose Y, Shindo N, Mori M, Onitsuka S, Isogai H, Hamada R, Hiramoto T, Ochi J, Takahashi D, Ueda T, Caaveiro JMM, Yoshida Y, Ohdo S, Matsunaga N, Toba S, Sasaki M, Orba Y, Sawa H, Sato A, Kawanishi E, Ojida A.
Discovery of Chlorofluoroacetamide-Based Covalent Inhibitors for Severe Acute Respiratory Syndrome Coronavirus 2 3CL Protease
J Med Chem
2022
65(20):13852-13865
PubMed ID: 36229406
DOI: 10.1021/acs.jmedchem.2c01081
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21141
Suenaga T, Mori Y, Suzutani T, Arase H.
Siglec-7 mediates varicella-zoster virus infection by associating with glycoprotein B.
Biochem Biophys Res Commun
2022
607:67-72
PubMed ID: 35367830
DOI: 10.1016/j.bbrc.2022.03.060
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22173
Ishibashi R, Maki R, Kitano S, Miyachi H, Toyoshima F.
Development of an in vivo cleavable donor plasmid for targeted transgene integration by CRISPR-Cas9 and CRISPR-Cas12a
Sci Rep
2022
12(1):17775
PubMed ID: 36272994
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Yim WW, Yamamoto H, Mizushima N.
A pulse-chasable reporter processing assay for mammalian autophagic flux with HaloTag
Elife
2022
11:e78923
PubMed ID: 35938926
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22175
Matsumoto N, Sekiya M, Sun-Wada GH, Wada Y, Nakanishi-Matsui M.
The lysosomal V-ATPase a3 subunit is involved in localization of Mon1-Ccz1, the GEF for Rab7, to secretory lysosomes in osteoclasts
Sci Rep
2022
12(1):8455
PubMed ID: 35589873
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Takahashi G, Kondo D, Maeda M, Morishita Y, Miyaoka Y.
Genome editing is induced in a binary manner in single human cells
iScience
2022
25(12):105619
PubMed ID: 36483018
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22257
Ichinose M, Kawabata M, Akaiwa Y, Shimajiri Y, Nakamura I, Tamai T, Nakamura T, Yagi Y, Gutmann B.
U-to-C RNA editing by synthetic PPR-DYW proteins in bacteria and human culture cells
Commun Biol
2022
5(1):968
PubMed ID: 36109586
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22258
Maeda Y, Watanabe T, Izumi T, Kuriyama K, Ohno S, Fujimuro M.
Biomolecular Fluorescence Complementation Profiling and Artificial Intelligence Structure Prediction of the Kaposi's Sarcoma-Associated Herpesvirus ORF18 and ORF30 Interaction
Int J Mol Sci
2022
23(17):9647
PubMed ID: 36077046
DOI: 10.3390/ijms23179647
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22259
Sato M, Sato-Yamamoto N, Wakita A, Haraguchi M, Shimonishi M, Okuno H.
Direct Injection of Recombinant AAV-Containing Solution into the Oviductal Lumen of Pregnant Mice Caused In Situ Infection of Both Preimplantation Embryos and Oviductal Epithelium
Int J Mol Sci
2022
23(9):4897
PubMed ID: 35563284
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22293
Maruyama T, Mano A, Ishii T, Kakinuma Y, Kaneda M.
P2X2 receptors supply extracellular choline as a substrate for acetylcholine synthesis
FEBS Open Bio
2022
12(1):250-257.
PubMed ID: 34787962
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Matsui Y, Mineharu Y, Noguchi Y, Hattori EY, Kubota H, Hirata M, Miyamoto S, Sugiyama H, Arakawa Y, Kamikubo Y.
Chlorambucil-conjugated PI-polyamides (Chb-M'), a transcription inhibitor of RUNX family, has an anti-tumor activity against SHH-type medulloblastoma with p53 mutatio
Biochem Biophys Res Commun
2022
620:150-157
PubMed ID: 35792512
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22321
Hatayama M, Katayama KI, Kawahara Y, Matsunaga H, Takashima N, Iwayama Y, Matsumoto Y, Nishi A, Yoshikawa T, Aruga J.
SLITRK1-mediated noradrenergic projection suppression in the neonatal prefrontal cortex
Commun Biol
2022
5(1):935
PubMed ID: 36085162
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22429
Somiya M, Kuroda S.
Engineering of Extracellular Vesicles for Small Molecule-Regulated Cargo Loading and Cytoplasmic Delivery of Bioactive Proteins
Mol Pharm
2022
19(7):2495-2505
PubMed ID: 35594496
DOI: 10.1021/acs.molpharmaceut.2c00192
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17694
Furuta T, Yamauchi K, Okamoto S, Takahashi M, Kakuta S, Ishida Y, Takenaka A, Yoshida A, Uchiyama Y, Koike M, Isa K, Isa T, Hioki H.
Multi-scale light microscopy/electron microscopy neuronal imaging from brain to synapse with a tissue clearing method, Sca l eSF
iScience
2021
25(1):103601
PubMed ID: 35106459
DOI: 10.1016/j.isci.2021.103601
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19485
Uehara T, Sanuki R, Ogura Y, Yokoyama A, Yoshida T, Futagawa H, Yoshihashi H, Yamada M, Suzuki H, Takenouchi T, Matsubara K, Hirata H, Kosaki K, Takano-Shimizu T.
Recurrent NFIA K125E substitution represents a loss-of-function allele: Sensitive in vitro and in vivo assays for nontruncating alleles
Am J Med Genet A
2021
185(7):2084-2093
PubMed ID: 33973697
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12798
Johmura Y, Yamanaka T, Omori S, Wang TW, Sugiura Y, Matsumoto M, Suzuki N, Kumamoto S, Yamaguchi K, Hatakeyama S, Takami T, Yamaguchi R, Shimizu E, Ikeda K, Okahashi N, Mikawa R, Suematsu M, Arita M, Sugimoto M, Nakayama KI, Furukawa Y, Imoto S, Nakanishi M.
Senolysis by glutaminolysis inhibition ameliorates various age-associated disorders
Science
2021
371(6526):265-270
PubMed ID: 33446552
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13320
Matsumoto N, Sekiya M, Fujimoto Y, Haga S, Sun-Wada GH, Wada Y, Nakanishi-Matsui M.
Functional complementation of V-ATPase a subunit isoforms in osteoclasts.
J Biochem
2021
169(4):459-466
PubMed ID: 33135054
DOI: 10.1093/jb/mvaa118
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13345
Daifu T, Mikami M, Hiramatsu H, Iwai A, Umeda K, Noura M, Kubota H, Masuda T, Furuichi K, Takasaki S, Noguchi Y, Morita K, Bando T, Hirata M, Kataoka TR, Nakahata T, Kuwahara Y, Iehara T, Hosoi H, Takita J, Sugiyama H, Adachi S, Kamikubo Y.
Suppression of malignant rhabdoid tumors through Chb-M'-mediated RUNX1 inhibition.
Pediatr Blood Cancer
2021
PubMed ID: 33180377
DOI: 10.1002/pbc.28789
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13351
Matsumoto Y, Kishida K, Matsumoto M, Matsuoka S, Kohyama M, Suenaga T, Arase H.
A TCR-like antibody against a proinsulin-containing fusion peptide ameliorates type 1 diabetes in NOD mice.
Biochem Biophys Res Commun
2021
PubMed ID: 33208230
DOI: 10.1016/j.bbrc.2020.11.019
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13463
Shota Someya et al
Tryptophan Metabolism Regulates Proliferative Capacity of Human Pluripotent Stem Cells
iScienc
2021
24
PubMed ID: 33615198
DOI: 10.1016/j.isci.2021.102090
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20008
Umaba R, Kitanishi T, Mizuseki K.
Monosynaptic connection from the subiculum to medial mammillary nucleus neurons projecting to the anterior thalamus and Gudden's ventral tegmental nucleus.
Neurosci Res
2021
PubMed ID: 33476683
DOI: 10.1016/j.neures.2021.01.006
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20053
Takafuji S, Mori T, Nishimura N, Yamamoto N, Uemura S, Nozu K, Terui K, Toki T, Ito E, Muramatsu H, Takahashi Y, Matsuo M, Yamamura T, Iijima K.
Usefulness of functional splicing analysis to confirm precise disease pathogenesis in Diamond-Blackfan anemia caused by intronic variants in RPS19.
Pediatr Hematol Oncol
2021
1-16
PubMed ID: 33622161
DOI: 10.1080/08880018.2021.1887984
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20060
Nishiike Y, Miyazoe D, Togawa R, Yokoyama K, Nakasone K, Miyata M, Kikuchi Y, Kamei Y, Todo T, Ishikawa-Fujiwara T, Ohno K, Usami T, Nagahama Y, Okubo K.
Estrogen receptor 2b is the major determinant of sex-typical mating behavior and sexual preference in medaka.
Curr Biol
2021
PubMed ID: 33639108
DOI: 10.1016/j.cub.2021.01.089
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13513
Takahashi Y, Wake H, Sakaguchi M, Yoshii Y, Teshigawara K, Wang D, Nishibori M.
Histidine-Rich Glycoprotein Stimulates Human Neutrophil Phagocytosis and Prolongs Survival through CLEC1A
J Immunol
2021
206(4):737-750
PubMed ID: 33452125
DOI: 10.4049/jimmunol.2000817
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20067
Aizawa N, Fujimori Y, Nakanishi O, Hayashi T, Goi Y, Kobayashi JI, Fujita T.
Efficacy of the combination of KPR-5714, a novel transient receptor potential melastatin 8 (TRPM8) antagonist, and β3-adrenoceptor agonist or anticholinergic agent on bladder dysfunction in rats with bladder overactivity.
Eur J Pharmacol
2021
173995
PubMed ID: 33675781
DOI: 10.1016/j.ejphar.2021.173995
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20068
Nakamura R, Oyama T, Inokuchi M, Ishikawa S, Hirata M, Kawashima H, Ikeda H, Dobashi Y, Ooi A.
Neural EGFL like 2 expressed in myoepithelial cells and suppressed breast cancer cell migration.
Pathol Int
2021
PubMed ID: 33657249
DOI: 10.1111/pin.13087
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13640
Fujita K, Koide N, Somiya M, Kuroda S, Hinuma S.
A regulatory role of scavenger receptor class B type 1 in endocytosis and lipid droplet formation induced by liposomes containing phosphatidylethanolamine in HEK293T cells
Biochim Biophys Acta Mol Cell Res
2021
1868(1):118859
PubMed ID: 32956759
DOI: 10.1016/j.bbamcr.2020.118859
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20083
Hama K, Fujiwara Y, Hayama T, Ozawa T, Nozawa K, Matsuda K, Hashiguchi Y, Yokoyama K.
Very long-chain fatty acids are accumulated in triacylglycerol and nonesterified forms in colorectal cancer tissues.
Sci Rep
2021
11(1):6163
PubMed ID: 33731797
DOI: 10.1038/s41598-021-85603-w
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20103
McKee HK, Kajiwara C, Yamaguchi T, Ishii Y, Shimizu N, Ohara A, Tateda K.
Clostridioides difficile toxins enhanced the in vitro production of CXC chemokine ligand 2 and tumor necrosis factor-α via Toll-like receptors in macrophages.
J Med Microbiol
2021
70(4)
PubMed ID: 33830910
DOI: 10.1099/jmm.0.001342
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13898
Takuma Kitanishi, Ryoko Umaba, Kenji Mizuseki
Robust information routing by dorsal subiculum neurons
Sci Adv
2021
7(11):eabf1913
PubMed ID: 33692111
DOI: 10.1126/sciadv.abf1913
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13913
Rai D, Akagi T, Shimohata A, Ishii T, Gangi M, Maruyama T, Wada-Kiyama Y, Ogiwara I, Kaneda M.
Involvement of the C-terminal domain in cell surface localization and G-protein coupling of mGluR6
J Neurochem
2021
158(4):837-848
PubMed ID: 33067823
DOI: 10.1111/jnc.15217
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20114
Ojiro I, Nishio H, Yamazaki-Ito T, Nakano S, Ito S, Toyohara Y, Hiramoto T, Terada Y, Ito K.
Trp-Trp acts as a multi-functional blocker for human bitter taste receptors, hTAS2R14, hTAS2R16, hTAS2R43, and hTAS2R46.
Biosci Biotechnol Biochem
2021
PubMed ID: 33844825
DOI: 10.1093/bbb/zbab061
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20138
Nagumo Y, Kandori S, Tanuma K, Nitta S, Chihara I, Shiga M, Hoshi A, Negoro H, Kojima T, Mathis BJ, Funakoshi Y, Nishiyama H.
PLD1 promotes tumor invasion by regulation of MMP-13 expression via NF-κB signaling in bladder cancer.
Cancer Lett
2021
511:15-25
PubMed ID: 33945837
DOI: 10.1016/j.canlet.2021.04.014
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20147
Kariya Y, Oyama M, Suzuki T, Kariya Y.
αvβ3 Integrin induces partial EMT independent of TGF-β signaling.
Commun Biol
2021
4(1):490
PubMed ID: 33883697
DOI: 10.1038/s42003-021-02003-6
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14182
Somiya M, Kuroda S.
Real-Time Luminescence Assay for Cytoplasmic Cargo Delivery of Extracellular Vesicles
Anal Chem
2021
93(13):5612-5620
PubMed ID: 33759512
DOI: 10.1021/acs.analchem.1c00339
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20150
Takeshita M, Suzuki K, Nakazawa M, Kamata H, Ishii M, Oyamada Y, Oshima H, Takeuchi T.
Antigen-driven autoantibody production in lungs of interstitial lung disease with autoimmune disease.
J Autoimmun
2021
121:102661
PubMed ID: 34034155
DOI: 10.1016/j.jaut.2021.102661
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20155
Sahoo PR, Kowada T, Mizukami S.
Long-Term Mg2+ Imaging in Live Cells with a Targetable Fluorescent Probe.
Methods Mol Biol
2021
2274:237-243
PubMed ID: 34050476
DOI: 10.1007/978-1-0716-1258-3_20
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20157
Matsui H, Ito J, Matsui N, Uechi T, Onodera O, Kakita A.
Cytosolic dsDNA of mitochondrial origin induces cytotoxicity and neurodegeneration in cellular and zebrafish models of Parkinson's disease.
Nat Commun
2021
12(1):3101
PubMed ID: 34035300
DOI: 10.1038/s41467-021-23452-x
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20158
Osakabe K, Wada N, Murakami E, Miyashita N, Osakabe Y.
Genome editing in mammalian cells using the CRISPR type I-D nuclease.
Nucleic Acids Res
2021
PubMed ID: 34076237
DOI: 10.1093/nar/gkab348
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20165
Kobayashi JI, Hirasawa H, Fujimori Y, Nakanishi O, Kamada N, Ikeda T, Yamamoto A, Kanbe H.
Identification of N-acyl-N-indanyl-α-phenylglycinamides as selective TRPM8 antagonists designed to mitigate the risk of adverse effects.
Bioorg Med Chem
2021
30:115903
PubMed ID: 33333445
DOI: 10.1016/j.bmc.2020.115903
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14478
Yamanaka D, Shoda M, Matsubara T, Ishibashi KI, Motoi A, Motoi R, Motoi M, Ohno N, Adachi Y.
Open-Label Study of the Influence of Food Containing the Royal Sun Mushroom, Agaricus brasiliensis KA21 (Agaricomycetes), on β-Glucan-Specific Antibody Production in Healthy Human Volunteers
Int J Med Mushrooms
2021
23(2):13-28
PubMed ID: 33639078
DOI: 10.1615/IntJMedMushrooms.2020037471
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20199
Tomita T, Kato M, Mishima T, Matsunaga Y, Sanjo H, Ito KI, Minagawa K, Matsui T, Oikawa H, Takahashi S, Takao T, Iwai N, Mino T, Takeuchi O, Maru Y, Hiratsuka S.
Extracellular mRNA transported to the nucleus exerts translation-independent function.
Nat Commun
2021
12(1):3655
PubMed ID: 34135341
DOI: 10.1038/s41467-021-23969-1
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20200
Kuwabara S, Tanimoto Y, Okutani M, Jie M, Haseda Y, Kinugasa-Katayama Y, Aoshi T.
Microfluidics sorting enables the isolation of an intact cellular pair complex of CD8+ T cells and antigen-presenting cells in a cognate antigen recognition-dependent manner.
PLoS One
2021
16(6):e0252666
PubMed ID: 34125844
DOI: 10.1371/journal.pone.0252666
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20216
Niinae T, Imami K, Sugiyama N, Ishihama Y.
Identification of Endogenous Kinase Substrates by Proximity Labeling Combined with Kinase Perturbation and Phosphorylation Motifs.
Mol Cell Proteomics
2021
100119
PubMed ID: 34186244
DOI: 10.1016/j.mcpro.2021.100119
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14782
Uemura K, Sasaki M, Sanaki T, Toba S, Takahashi Y, Orba Y, Hall WW, Maenaka K, Sawa H, Sato A.
MRC5 cells engineered to express ACE2 serve as a model system for the discovery of antivirals targeting SARS-CoV-2
Sci Rep
2021
11(1):5376
PubMed ID: 33686154
DOI: 10.1038/s41598-021-84882-7
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14827
iu Y, Soh WT, Kishikawa JI, Hirose M, Nakayama EE, Li S, Sasai M, Suzuki T, Tada A, Arakawa A, Matsuoka S, Akamatsu K, Matsuda M, Ono C, Torii S, Kishida K, Jin H, Nakai W, Arase N, Nakagawa A, Matsumoto M, Nakazaki Y, Shindo Y, Kohyama M, Tomii K, Ohmura K, Ohshima S, Okamoto T, Yamamoto M, Nakagami H, Matsuura Y, Nakagawa A, Kato T, Okada M, Standley DM, Shioda T, Arase H.
An infectivity-enhancing site on the SARS-CoV-2 spike protein targeted by antibodies
Cell
2021
184(13):3452-3466.e18
PubMed ID: 34139176
DOI: 10.1016/j.cell.2021.05.032
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20233
Koshizuka T, Kondo H, Kato H, Takahashi K.
Human cytomegalovirus UL42 protein inhibits the degradation of glycoprotein B through inhibition of Nedd4 family ubiquitin E3 ligases.
Microbiol Immunol
2021
PubMed ID: 34260096
DOI: 10.1111/1348-0421.12932
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20240
Kaku T, Sugiura K, Entani T, Osabe K, Nagai T.
Enhanced brightness of bacterial luciferase by bioluminescence resonance energy transfer.
Sci Rep
2021
11(1):14994
PubMed ID: 34294849
DOI: 10.1038/s41598-021-94551-4
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14939
Shuji Hinuma, Kazuyo Fujita, Shun’ichi Kuroda
Binding of Nanoparticles Harboring Recombinant Large Surface Protein of Hepatitis B Virus to Scavenger Receptor Class B Type 1
Viruses
2021
13:1334
PubMed ID: 34372540
DOI: 10.3390/v13071334
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20244
Yoshioka K, Obara K, Oikawa S, Uemura K, Yamaguchi A, Fujisawa K, Hanazawa H, Fujiwara M, Endoh T, Suzuki T, Regadera MD, Ito D, Ou G, Xu K, Tanaka Y.
Docosahexaenoic acid inhibits U46619- and prostaglandin F2α-induced pig coronary and basilar artery contractions by inhibiting prostanoid TP receptors.
Eur J Pharmacol
2021
174371
PubMed ID: 34329614
DOI: 10.1016/j.ejphar.2021.174371
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20272
Ma Y, Yoshida T, Matoba K, Kida K, Shintani R, Piao Y, Jin J, Nishino T, Hanayama R.
Identification of small compounds regulating the secretion of extracellular vesicles via a TIM4-affinity ELISA.
Sci Rep
2021
11(1):13471
PubMed ID: 34188113
DOI: 10.1038/s41598-021-92860-2
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15168
Hangai S, Kawamura T, Kimura Y, Chang CY, Hibino S, Yamamoto D, Nakai Y, Tateishi R, Oshima M, Oshima H, Kodama T, Moriya K, Koike K, Yanai H, Taniguchi T.
Orchestration of myeloid-derived suppressor cells in the tumor microenvironment by ubiquitous cellular protein TCTP released by tumor cells
Nat Immunol
2021
22(8):947-957
PubMed ID: 34239121
DOI: 10.1038/s41590-021-00967-5
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20282
Nakanishi E, Uemura N, Akiyama H, Kinoshita M, Masanori S, Taruno Y, Yamakado H, Matsuzawa SI, Takeda S, Hirabayashi Y, Takahashi R.
Impact of Gba2 on neuronopathic Gaucher's disease and α-synuclein accumulation in medaka (Oryzias latipes).
Mol Brain
2021
14(1):80
PubMed ID: 33971917
DOI: 10.1186/s13041-021-00790-x
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20283
Sakoguchi A, Saito F, Hirayasu K, Shida K, Matsuoka S, Itagaki S, Nakai W, Kohyama M, Suenaga T, Iwanaga S, Horii T, Arase H.
Plasmodium falciparum RIFIN is a novel ligand for inhibitory immune receptor LILRB2.
Biochem Biophys Res Commun
2021
548:167-173
PubMed ID: 33647792
DOI: 10.1016/j.bbrc.2021.02.033
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20298
Nagano C, Takaoka Y, Kamei K, Hamada R, Ichikawa D, Tanaka K, Aoto Y, Ishiko S, Rossanti R, Sakakibara N, Okada E, Horinouchi T, Yamamura T, Tsuji Y, Noguchi Y, Ishimori S, Nagase H, Ninchoji T, Iijima K, Nozu K.
Genotype-Phenotype Correlation in WT1 Exon 8 to 9 Missense Variants.
Kidney Int Rep
2021
6(8):2114-2121
PubMed ID: 34386660
DOI: 10.1016/j.ekir.2021.05.009
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20322
Fujisawa S, Qiu H, Nozaki S, Chiba S, Katoh Y, Nakayama K.
ARL3 and ARL13B GTPases participate in distinct steps of INPP5E targeting to the ciliary membrane.
Biol Open
2021
PubMed ID: 34447983
DOI: 10.1242/bio.058843
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15284
Yoshiko Iizuka, Kinuko Inomata, Risako Nohara, Akimitsu Miyawaki and Yoshifumi Watanabe
Activation of intracellular antioxidant master gene Nrf2 by the extracts of Garcinia subelliptica, Ocimum gratissimum L., and Plectranthus ornatus
International Journal of Herbal Medicine
2021
9(3):54-60
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15524
Fukasawa K, Kadota T, Horie T, Tokumura K, Terada R, Kitaguchi Y, Park G, Ochiai S, Iwahashi S, Okayama Y, Hiraiwa M, Yamada T, Iezaki T, Kaneda K, Yamamoto M, Kitao T, Shirahase H, Hazawa M, Wong RW, Todo T, Hirao A, Hinoi E.
CDK8 maintains stemness and tumorigenicity of glioma stem cells by regulating the c-MYC pathway
Oncogene
2021
40(15):2803-2815
PubMed ID: 33727660
DOI: 10.1038/s41388-021-01745-1
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20354
Noguchi T, Nakamura K, Satoda Y, Katoh Y, Nakayama K.
CCRK/CDK20 regulates ciliary retrograde protein trafficking via interacting with BROMI/TBC1D32.
PLoS One
2021
16(10):e0258497
PubMed ID: 34624068
DOI: 10.1371/journal.pone.0258497
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20356
Yasumura M, Hagiwara A, Hida Y, Ohtsuka T.
Planar cell polarity protein Vangl2 and its interacting protein Ap2m1 regulate dendritic branching in cortical neurons.
Genes Cells
2021
PubMed ID: 34626136
DOI: 10.1111/gtc.12899
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20367
Kariya Y, Oyama M, Kariya Y, Hashimoto Y.
Phosphorylated Osteopontin Secreted from Cancer Cells Induces Cancer Cell Motility.
Biomolecules
2021
11(9)
PubMed ID: 34572536
DOI: 10.3390/biom11091323
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20403
Yaguchi A, Oshikawa M, Watanabe G, Hiramatsu H, Uchida N, Hara C, Kaneko N, Sawamoto K, Muraoka T, Ajioka I.
Efficient protein incorporation and release by a jigsaw-shaped self-assembling peptide hydrogel for injured brain regeneration.
Nat Commun
2021
12(1):6623
PubMed ID: 34799548
DOI: 10.1038/s41467-021-26896-3
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20440
Kanadome T, Hoshino N, Nagai T, Matsuda T, Yagi T.
Development of FRET-based indicators for visualizing homophilic trans interaction of a clustered protocadherin.
Sci Rep
2021
11(1):22237
PubMed ID: 34782670
DOI: 10.1038/s41598-021-01481-2
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15879
Uemura K, Nobori H, Sato A, Sanaki T, Toba S, Sasaki M, Murai A, Saito-Tarashima N, Minakawa N, Orba Y, Kariwa H, Hall WW, Sawa H, Matsuda A, Maenaka K.
5-Hydroxymethyltubercidin exhibits potent antiviral activity against flaviviruses and coronaviruses, including SARS-CoV-2
iScience
2021
24(10):103120
PubMed ID: 34541466
DOI: 10.1016/j.isci.2021.103120
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15898
Yafei Liu, Noriko Arase, Jun-ichi Kishikawa, Mika Hirose, Songling Li, Asa Tada, Sumiko Matsuoka, Akemi Arakawa, Kanako Akamatsu, Chikako Ono, Hui Jin, Kazuki Kishida, Wataru Nakai, Masako Kohyama, Atsushi Nakagawa, Yoshiaki Yamagishi, Hironori Nakagami, Atsushi Kumanogoh, Yoshiharu Matsuura, Daron M. Standley, Takayuki Kato, Masato Okada, Manabu Fujimoto, Hisashi Arase
The SARS-CoV-2 Delta variant is poised to acquire complete resistance to wild-type spike vaccines
bioRxiv
2021
DOI: 10.1101/2021.08.22.457114
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20490
Ito F, Kato K, Yanatori I, Murohara T, Toyokuni S.
Ferroptosis-dependent extracellular vesicles from macrophage contribute to asbestos-induced mesothelial carcinogenesis through loading ferritin.
Redox Biol
2021
47:102174
PubMed ID: 34700146
DOI: 10.1016/j.redox.2021.102174
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20493
Ishida H, Murakami S, Kamiki H, Matsugo H, Katayama M, Sekine W, Ohira K, Takenaka-Uema A, Horimoto T.
Construction of an Influenza D Virus with an Eight-Segmented Genome.
Viruses
2021
13(11)
PubMed ID: 34834971
DOI: 10.3390/v13112166
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J Virol
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Effective RNA Knockdown Using CRISPR-Cas13a and Molecular Targeting of the EML4-ALK Transcript in H3122 Lung Cancer Cells
Effective RNA Knockdown Using CRISPR-Cas13a and Molecular Targeting of the EML4-ALK Transcript in H3122 Lung Cancer Cells
Int J Mol Sci
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An Antiviral Drug Screening Platform with a FRET Biosensor for Measurement of Arenavirus Z Assembly
Cell Struct Funct
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Toda K, Tsukayama I, Nagasaki Y, Konoike Y, Tamenobu A, Ganeko N, Ito H, Kawakami Y, Takahashi Y, Miki Y, Yamamoto K, Murakami M, Suzuki-Yamamoto T.
Red-kerneled rice proanthocyanidin inhibits arachidonate 5-lipoxygenase and decreases psoriasis-like skin inflammation
Arch Biochem Biophys
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Synthesis of C12-Keto Saxitoxin Derivatives with Unusual Inhibitory Activity Against Voltage-Gated Sodium Channels
Chemistry
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J Reprod Dev
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Inhibition of the glutamine transporter SNAT1 confers neuroprotection in mice by modulating the mTOR-autophagy system
Commun Biol
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FASEB J.
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Mizuno M, Miki R, Moriyama Y, Ushida T, Imai K, Niimi K, Nakano T, Tsuda H, Sumigama S, Yamamoto E, Senga T, Iwase A, Kikkawa F, Kotani T.
The role of E2F8 in the human placenta.
Mol Med Rep
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Globo-series glycosphingolipids enhance Toll-like receptor 4-mediated inflammation and play a pathophysiological role in diabetic nephropathy.
Glycobiology
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Arai Y, Ibrahim MS, Elgendy EM, Daidoji T, Ono T, Suzuki Y, Nakaya T, Matsumoto K, Watanabe Y.
Genetic Compatibility of Reassortants between Avian H5N1 and H9N2 Influenza Viruses with Higher Pathogenicity in Mammals.
J. Virol.
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Mol. Cell. Biochem.
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J. Biol. Chem.
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Elife
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Kataoka K, Miyoshi H, Sakata S, Dobashi A, Couronné L, Kogure Y, Sato Y, Nishida K, Gion Y, Shiraishi Y, Tanaka H, Chiba K, Watatani Y, Kakiuchi N, Shiozawa Y, Yoshizato T, Yoshida K, Makishima H, Sanada M, Onozawa M, Teshima T, Yoshiki Y, Ishida T, Suzuki K, Shimada K, Tomita A, Kato M, Ota Y, Izutsu K, Demachi-Okamura A, Akatsuka Y, Miyano S, Yoshino T, Gaulard P, Hermine O, Takeuchi K, Ohshima K, Ogawa S.
Frequent structural variations involving programmed death ligands in Epstein-Barr virus-associated lymphomas.
Leukemia
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Proton pumping V-ATPase inhibitor bafilomycin A1 affects Rab7 lysosomal localization and abolishes anterograde trafficking of osteoclast secretory lysosomes.
Biochem. Biophys. Res. Commun.
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Int. Immunol.
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Type I interferon protects neurons from prions in in vivo models.
Brain
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Biochem. Biophys. Res. Commun.
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Degradation of p47 by autophagy contributes to CADM1 overexpression in ATLL cells through the activation of NF-κB.
Sci Rep
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Melanoma cell adhesion molecule is the driving force behind the dissemination of melanoma upon S100A8/A9 binding in the original skin lesion.
Cancer Lett.
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TRPM4 and TRPM5 Channels Share Crucial Amino Acid Residues for Ca2+ Sensitivity but Not Significance of PI(4,5)P2.
Int J Mol Sci
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HCV IRES Captures an Actively Translating 80S Ribosome.
Mol Cell
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Int. J. Oncol.
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Int. J. Oncol.
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Exp. Cell Res.
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Critical role of the MCAM-ETV4 axis triggered by extracellular S100A8/A9 in breast cancer aggressiveness.
Neoplasia
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Tanaka J, Mabuchi Y, Hata K, Yasuhara R, Takamatsu K, Kujiraoka S, Yukimori A, Takakura I, Sumimoto H, Fukada T, Azuma M, Akiyama H, Nishimura R, Shimane T, Mishima K.
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Exp. Cell Res.
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PB2 mutations arising during H9N2 influenza evolution in the Middle East confer enhanced replication and growth in mammals.
PLoS Pathog.
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Evolutionary and Functional Diversity of the 5' Untranslated Region of Enterovirus D68: Increased Activity of the Internal Ribosome Entry Site of Viral Strains during the 2010s.
Viruses
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Ishii J, Suzuki A, Kimura T, Tateyama M, Tanaka T, Yazawa T, Arimasu Y, Chen IS, Aoyama K, Kubo Y, Saitoh S, Mizuno H, Kamma H.
Congenital goitrous hypothyroidism is caused by dysfunction of the iodide transporter SLC26A7.
Commun Biol
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Identification of intermediate-sized deletions and inference of their impact on gene expression in a human population.
Genome Med
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Single cell RNA-sequencing identified Dec2 as a suppressive factor for spermatogonial differentiation by inhibiting Sohlh1 expression.
Sci Rep
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Yamanashi T, Maki M, Kojima K, Shibukawa A, Tsukamoto T, Chowdhury S, Yamanaka A, Takagi S, Sudo Y.
Quantitation of the neural silencing activity of anion channelrhodopsins in Caenorhabditis elegans and their applicability for long-term illumination.
Sci Rep
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Sequence-specific retrotransposition of 28S rDNA-specific LINE R2Ol in human cells.
RNA
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Kamiki H, Matsugo H, Ishida H, Kobayashi-Kitamura T, Sekine W, Takenaka-Uema A, Murakami S, Horimoto T.
Adaptation of H3N2 canine influenza virus to feline cell culture.
PLoS ONE
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Morita A, Aoshima K, Gulay KCM, Onishi S, Shibata Y, Yasui H, Kobayashi A, Kimura T.
High drug efflux pump capacity and low DNA damage response induce doxorubicin resistance in canine hemangiosarcoma cell lines.
Res. Vet. Sci.
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Musha S, Nagayama S, Murakami S, Kojima R, Deai M, Sato K, Okajima F, Ueharu H, Tomura H.
Protons Differentially Activate TDAG8 Homologs from Various Species.
Zoolog Sci
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Nakanishi M, Hino M, Yoshimura M, Amakura Y, Nomoto H.
Identification of sinensetin and nobiletin as major antitrypanosomal factors in a citrus cultivar.
Exp Parasitol
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Kazuyo Fujita, Masaharu Somiya, Shun'ichi Kuroda, Shuji Hinuma
Induction of Lipid Droplets in Non-Macrophage Cells as Well as Macrophages by Liposomes and Exosomes
Biochem Biophys Res Commun
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Uchibori R, Teruya T, Ido H, Ohmine K, Sehara Y, Urabe M, Mizukami H, Mineno J, Ozawa K.
Functional Analysis of an Inducible Promoter Driven by Activation Signals from a Chimeric Antigen Receptor
Mol Ther Oncolytics
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Arisa Mitani, Takeshi Kobayashi, Yasuhito Hayashi, Natsuki Matsushita, Sachi Matsushita, Saori Nakao, Naoko Takahira, Atsushi Shiraishi, Yuichi Ohashi
Characterization of doxycycline-dependent inducible Simian Virus 40 large T antigen immortalized human conjunctival epithelial cell line
PLoS One
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Nobuyoshi Tajima, Liu Xiaoyan, Makoto Taniguchi, Nobuo Kato
24S-hydroxycholesterol alters activity of large-conductance Ca 2+-dependent K + (slo1 BK) channel through intercalation into plasma membrane
Biochim Biophys Acta Mol Cell Biol Lipids
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1864(10):1525-1535
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Shimizu K, Yamasaki S, Sakurai M, Yumoto N, Ikeda M, Mishima-Tsumagari C, Kukimoto-Niino M, Watanabe T, Kawamura M, Shirouzu M, Fujii SI.
Granzyme A Stimulates pDCs to Promote Adaptive Immunity via Induction of Type I IFN
Front Immunol
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Takahashi Y, Takahashi H, Stern PL, Kirita T, Tsuboi A.
Expression of Oncofetal Antigen 5T4 in Murine Taste Papillae
Front Cell Neurosci
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Ichikawa T, Nakahata S, Fujii M, Iha H, Shimoda K, Morishita K.
The regulation of NDRG2 expression during ATLL development after HTLV-1 infection
Biochim Biophys Acta Mol Basis Dis
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Okamura M, Shizu R, Hosaka T, Sasaki T, Yoshinari K.
Possible involvement of the competition for the transcriptional coactivator glucocorticoid receptor-interacting protein 1 in the inflammatory signal-dependent suppression of PXR-mediated CYP3A induction in vitro
Drug Metab Pharmacokinet
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Mitsui Y, Tomonobu N, Watanabe M, Kinoshita R, Sumardika IW, Youyi C, Murata H, Yamamoto KI, Sadahira T, Rodrigo AGH, Takamatsu H, Araki K, Yamauchi A, Yamamura M, Fujiwara H, Inoue Y, Futami J, Saito K, Iioka H, Kondo E, Nishibori M, Toyooka S, Yamamoto Y, Nasu Y, Sakaguchi M.
Upregulation of Mobility in Pancreatic Cancer Cells by Secreted S100A11 Through Activation of Surrounding Fibroblasts
Oncol Res
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Quantitative analysis of the effects of nicotinamide phosphoribosyltransferase induction on the rates of NAD+ synthesis and breakdown in mammalian cells using stable isotope-labeling combined with mass spectrometry
PLoS One
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Mechanism underlying the retarded nuclear translocation of androgen receptor splice variants
Sci China Life Sci
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Yoh T, Hatano E, Kasai Y, Fuji H, Nishi K, Toriguchi K, Sueoka H, Ohno M, Seo S, Iwaisako K, Taura K, Yamaguchi R, Kurokawa M, Fujimoto J, Kimura T, Uemoto S, Nishi E.
Serum Nardilysin, a Surrogate Marker for Epithelial-Mesenchymal Transition, Predicts Prognosis of Intrahepatic Cholangiocarcinoma after Surgical Resection
Clin Cancer Res
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Maishi N, Kikuchi H, Sato M, Nagao-Kitamoto H, Annan DA, Baba S, Hojo T, Yanagiya M, Ohba Y, Ishii G, Masutomi K, Shinohara N, Hida Y, Hida K.
Development of Immortalized Human Tumor Endothelial Cells from Renal Cancer
Int J Mol Sci
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Neuroplastin-β mediates S100A8/A9-induced lung cancer disseminative progression
Mol Carcinog
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Horigome E, Fujieda M, Handa T, Katayama A, Ito M, Ichihara A, Tanaka D, Gombodorj N, Yoshiyama S, Yamane A, Yamada K, Horiguchi J, Shinozuka K, Oyama T, Nishiyama M, Rokudai S.
Mutant TP53 modulates metastasis of triple negative breast cancer through adenosine A2b receptor signaling
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JCI Insight
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Sci Rep
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Zool. Sci.
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Development
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SPIE BiOS
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Large-scale forward genetics screening identifies Trpa1 as a chemosensor for predator odor-evoked innate fear behaviors.
Nat Commun
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Arch. Biochem. Biophys.
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Nat Commun
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Cell Chem Biol
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EMBO Mol Med
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Retrovirology
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Cell Rep
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Sci Rep
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Immune evasion of Plasmodium falciparum by RIFIN via inhibitory receptors.
Nature
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Discovery of a novel antiviral agent targeting the nonstructural protein 4 (nsP4) of chikungunya virus.
Virology
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Myeloperoxidase/HLA Class II Complexes Recognized by Autoantibodies in Microscopic Polyangiitis.
Arthritis Rheumatol
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Blood Adv
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Structural analysis of the STAT1:STAT2 heterodimer revealed the mechanism of Sendai virus C protein-mediated blockade of type 1 interferon signaling.
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FAD influx enhances neuronal differentiation of human neural stem cells by facilitating nuclear localization of LSD1.
FEBS Open Bio
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An in vitro splicing assay reveals the pathogenicity of a novel intronic variant in ATP6V0A4 for autosomal recessive distal renal tubular acidosis.
BMC Nephrol
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A screening system to identify transcription factors that induce binding site-directed DNA demethylation.
Epigenetics Chromatin
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Biosci Biotechnol Biochem
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Jaerin Sohn, Megumu Takahashi, Shinichiro Okamoto, Yoko Ishida, Takahiro Furuta, Hiroyuki Hioki
A Single Vector Platform for High-Level Gene Transduction of Central Neurons: Adeno-Associated Virus Vector Equipped With the Tet-Off System
PLoS One
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Genetically encoded bioluminescent voltage indicator for multi-purpose use in wide range of bioimaging
Sci Rep
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Establishment of highly metastatic KRAS mutant lung cancer cell sublines in long-term three-dimensional low attachment cultures
PLoS Onec
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A chromosome 16p13.11 microduplication causes hyperactivity through dysregulation of miR-484/protocadherin-19 signaling
Mol Psychiatry
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Sustained Activation of the Unfolded Protein Response Induces Cell Death in Fuchs' Endothelial Corneal Dystrophy
Invest Ophthalmol Vis Sci
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Senga Y, Imamura H, Miyafusa T, Watanabe H, Honda S.
AlphaScreen-based homogeneous assay using a pair of 25-residue artificial proteins for high-throughput analysis of non-native IgG
Sci Rep
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Endo H, Tanaka S, Imamura K, Adegawa S, Kikuta S, Sato R.
Cry toxin specificities of insect ABCC transporters closely related to lepidopteran ABCC2 transporters
Peptides
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Development of a double-stranded siRNA labelling method by using 99m Tc and single photon emission computed tomography imaging
J Drug Target
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Differential binding of tetrodotoxin and its derivatives to voltage-sensitive sodium channel subtypes (Na v 1.1 to Na v 1.7)
Br J Pharmacol
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Wu DC, Wang SSW, Liu CJ, Wuputra K, Kato K, Lee YL, Lin YC, Tsai MH, Ku CC, Lin WH, Wang SW, Kishikawa S, Noguchi M, Wu CC, Chen YT, Chai CY, Lin CS, Kuo KK, Yang YH, Miyoshi H, Nakamura Y, Saito S, Nagata K, Lin CS, Yokoyama KK.
Reprogramming Antagonizes the Oncogenicity of HOXA13-Long Noncoding RNA HOTTIP Axis in Gastric Cancer Cells
Stem Cells
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Towards water-free biobanks: long-term dry-preservation at room temperature of desiccation-sensitive enzyme luciferase in air-dried insect cells
Sci Rep
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Synthesis and optimization of novel α-phenylglycinamides as selective TRPM8 antagonists
Bioorg Med Chem
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Identification of polymerase gene mutations that affect viral replication in H5N1 influenza viruses isolated from pigeons
J Gen Virol
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In vivo brain activity imaging of interactively locomoting mice
bioRxiv
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Dual control of pcdh8l/PCNS expression and function in Xenopus laevis neural crest cells by adam13/33 via the transcription factors tfap2α and arid3a
Elife
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Five colour variants of bright luminescent protein for real-time multicolour bioimaging.
Nat Commun
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Forward-genetics analysis of sleep in randomly mutagenized mice.
Nature
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Autonomous translational pausing is required for XBP1u mRNA recruitment to the ER via the SRP pathway.
Proc. Natl. Acad. Sci. U.S.A.
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Cell Cycle
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Insect Biochem Mol Biol
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Sialic Acids on Varicella-Zoster Virus Glycoprotein B Are Required for Cell-Cell Fusion
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Nat Commun
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Yamanishi M, Narazaki H, Asano T.
Melatonin overcomes resistance to clofarabine in two leukemic cell lines by increased expression of deoxycytidine kinase
Exp Hematol
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43(3):207-14
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Konoki K, Suga Y, Fuwa H, Yotsu-Yamashita M, Sasaki M.
Evaluation of gambierol and its analogs for their inhibition of human Kv1.2 and cytotoxicity
Bioorg Med Chem Lett
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10171
Fujiwara H, Ochi T, Ochi F, Miyazaki Y, Asai H, Narita M, Okamoto S, Mineno J, Kuzushima K, Shiku H, Yasukawa M.
Antileukemia multifunctionality of CD4(+) T cells genetically engineered by HLA class I-restricted and WT1-specific T-cell receptor gene transfer
Leukemia
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29(12):2393-401
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18179
Chiba S, Ikushima H, Ueki H, Yanai H, Kimura Y, Hangai S, Nishio J, Negishi H, Tamura T, Saijo S, Iwakura Y, Taniguchi T.
Recognition of tumor cells by Dectin-1 orchestrates innate immune cells for anti-tumor responses
Elife
2014
3:e04177
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7579
Suzuki-Nakagawa C, Nishimura M, Tsukamoto T, Aoyama S, Ebihara A, Suzuki F, Nakagawa T.
Participation of the extracellular domain in (pro)renin receptor dimerization.
Biochem. Biophys. Res. Commun.
2014
444:461-6
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19249
Ito S, Ueda T, Ueno A, Nakagawa H, Taniguchi H, Hongo F, Kamoi K, Okihara K, Kawauchi A, Miki T.
Paired box 2 upregulates androgen receptor gene expression in androgen-independent prostate cancer
FEBS J
2014
281(19):4506-18
PubMed ID: 25132193
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19338
Shoji S, Muto Y, Ikeda M, He F, Tsuda K, Ohsawa N, Akasaka R, Terada T, Wakiyama M, Shirouzu M, Yokoyama S.
The zinc-binding region (ZBR) fragment of Emi2 can inhibit APC/C by targeting its association with the coactivator Cdc20 and UBE2C-mediated ubiquitylation
FEBS Open Bio
2014
4:689-703
PubMed ID: 25161877
DOI: 10.1016/j.fob.2014.06.010
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19375
Sakaguchi M, Murata H, Aoyama Y, Hibino T, Putranto EW, Ruma IM, Inoue Y, Sakaguchi Y, Yamamoto K, Kinoshita R, Futami J, Kataoka K, Iwatsuki K, Huh NH.
DNAX-activating protein 10 (DAP10) membrane adaptor associates with receptor for advanced glycation end products (RAGE) and modulates the RAGE-triggered signaling pathway in human keratinocytes
J Biol Chem
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289(34):23389-402
PubMed ID: 25002577
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5836
Saito K, Sakaguchi M, Iioka H, Matsui M, Nakanishi H, Huh NH, Kondo E.
Coxsackie and adenovirus receptor is a critical regulator for the survival and growth of oral squamous carcinoma cells.
Oncogene
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33(10):1274-86
PubMed ID: 23503462
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14940
Okumura N, Hirano H, Numata R, Nakahara M, Ueno M, Hamuro J, Kinoshita S, Koizumi N.
Cell surface markers of functional phenotypic corneal endothelial cells
Invest Ophthalmol Vis Sci
2014
55(11):7610-8
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15805
Murakami-Tonami Y, Kishida S, Takeuchi I, Katou Y, Maris JM, Ichikawa H, Kondo Y, Sekido Y, Shirahige K, Murakami H, Kadomatsu K.
Inactivation of SMC2 shows a synergistic lethal response in MYCN-amplified neuroblastoma cells
Cell Cycle
2014
13(7):1115-31
PubMed ID: 24553121
DOI: 10.4161/cc.27983
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15812
Yamashita H, Ichikawa T, Matsuyama D, Kimura Y, Ueda K, Craig SW, Harada I, Kioka N.
The role of the interaction of the vinculin proline-rich linker region with vinexin α in sensing the stiffness of the extracellular matrix
J Cell Sci
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127(Pt 9):1875-86
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15829
Miyagawa-Yamaguchi A, Kotani N, Honke K.
Expressed glycosylphosphatidylinositol-anchored horseradish peroxidase identifies co-clustering molecules in individual lipid raft domains
PLoS One
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9(3):e93054
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Lu J, Isaji T, Im S, Fukuda T, Hashii N, Takakura D, Kawasaki N, Gu J.
β-Galactoside α2,6-sialyltranferase 1 promotes transforming growth factor-β-mediated epithelial-mesenchymal transition
J Biol Chem
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289(50):34627-41
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Ishikawa F, Kaneko E, Sugimoto T, Ishijima T, Wakamatsu M, Yuasa A, Sampei R, Mori K, Nose K, Shibanuma M.
A mitochondrial thioredoxin-sensitive mechanism regulates TGF-β-mediated gene expression associated with epithelial-mesenchymal transition
Biochem Biophys Res Commun
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443(3):821-7
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17090
Park HY, Toume K, Arai MA, Sadhu SK, Ahmed F, Ishibashi M.
Calotropin: a cardenolide from calotropis gigantea that inhibits Wnt signaling by increasing casein kinase 1α in colon cancer cells
Chembiochem
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Takano M, Kanoh A, Amako K, Otani M, Sano K, Kanazawa-Hamada M, Matsuyama S.
Nuclear localization of bradykinin B(2) receptors reflects binding to the nuclear envelope protein lamin C
Eur J Pharmacol
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723:507-14
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Goudarzi H, Hida Y, Takano H, Teramae H, Iizasa H, Hamada J.
Hypoxia affects in vitro growth of newly established cell lines from patients with malignant pleural mesothelioma
Biomed Res
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34(1):13-21
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Akimoto AM, Takarada T, Maeda M.
Preparation of cell-culturing glass surfaces that release branched polyethyleneimine triggered by thiol-disulfide exchange
Colloids Surf B Biointerfaces
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103:360-5
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19315
Tada T, Kadoki M, Liu Y, Tokunaga K, Iwakura Y.
Transgenic expression of the human LEDGF/p75 gene relieves the species barrier against HIV-1 infection in mouse cells
Front Microbiol
2013
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Ohnishi H, Sasaki H, Nakamura Y, Kato S, Ando K, Narimatsu H, Tachibana K.
Regulation of cell shape and adhesion by CD34
Cell Adh Migr
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7(5):426-33
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Kon A, Shih LY, Minamino M, Sanada M, Shiraishi Y, Nagata Y, Yoshida K, Okuno Y, Bando M, Nakato R, Ishikawa S, Sato-Otsubo A, Nagae G, Nishimoto A, Haferlach C, Nowak D, Sato Y, Alpermann T, Nagasaki M, Shimamura T, Tanaka H, Chiba K, Yamamoto R, Yamaguchi T, Otsu M, Obara N, Sakata-Yanagimoto M, Nakamaki T, Ishiyama K, Nolte F, Hofmann WK, Miyawaki S, Chiba S, Mori H, Nakauchi H, Koeffler HP, Aburatani H, Haferlach T, Shirahige K, Miyano S, Ogawa S.
Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms
Nat Genet
2013
45(10):1232-7
PubMed ID: 23955599
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15925
Takahashi K, Orba Y, Kimura T, Wang L, Kohsaka S, Tsuda M, Tanino M, Nishihara H, Nagashima K, Sawa H, Tanaka S.
Relationship between methyl CpG binding protein 2 and JC viral proteins
Jpn J Infect Dis
2013
66(2):126-32.
PubMed ID: 23514909
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15933
Koyama T, Sun B, Tokunaga K, Tatsumi M, Ishizaka Y.
DNA damage enhances integration of HIV-1 into macrophages by overcoming integrase inhibition
Retrovirology
2013
10:21
PubMed ID: 23432899
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16037
Yaguchi M, Ohashi Y, Tsubota T, Sato A, Koyano KW, Wang N, Miyashita Y.
Characterization of the properties of seven promoters in the motor cortex of rats and monkeys after lentiviral vector-mediated gene transfer
Hum Gene Ther Methods
2013
24(6):333-44
PubMed ID: 23964981
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16888
Haruta M, Tomita Y, Yuno A, Matsumura K, Ikeda T, Takamatsu K, Haga E, Koba C, Nishimura Y, Senju S.
TAP-deficient human iPS cell-derived myeloid cell lines as unlimited cell source for dendritic cell-like antigen-presenting cells
Gene Ther
2013
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PubMed ID: 22875043
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17160
Matsushita N, Matsushita S, Hirakawa S, Higashiyama S.
Doxycycline-dependent inducible and reversible RNA interference mediated by a single lentivirus vector
Biosci Biotechnol Biochem
2013
77(4):776-81
PubMed ID: 23563548
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21985
Okudaira N, Okamura T, Tamura M, Iijma K, Goto M, Matsunaga A, Ochiai M, Nakagama H, Kano S, Fujii-Kuriyama Y, Ishizaka Y.
Long interspersed element-1 is differentially regulated by food-borne carcinogens via the aryl hydrocarbon receptor.
Oncogene
2013
32(41):4903-12
PubMed ID: 23208499
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7627
Ohue Y, Eikawa S, Okazaki N, Mizote Y, Isobe M, Uenaka A, Fukuda M, Old LJ, Oka M, Nakayama E.
Spontaneous antibody, and CD4 and CD8 T-cell responses against XAGE-1b (GAGED2a) in non-small cell lung cancer patients.
Int. J. Cancer
2012
131:E649-58
PubMed ID: 22109656
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18593
Watanabe Y, Ibrahim MS, Ellakany HF, Kawashita N, Daidoji T, Takagi T, Yasunaga T, Nakaya T, Ikuta K.
Antigenic analysis of highly pathogenic avian influenza virus H5N1 sublineages co-circulating in Egypt
J Gen Virol
2012
93(Pt 10):2215-2226
PubMed ID: 22791605
DOI: 10.1099/vir.0.044032-0
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18740
Yamamoto-Suzuki Y, Sakurai Y, Fujimura Y, Matsumoto M, Hamako J, Kokubo T, Kitagawa H, Kawsar SM, Fujii Y, Ozeki Y, Matsushita F, Matsui T.
Identification and recombinant analysis of botrocetin-2, a snake venom cofactor for von Willebrand factor-induced platelet agglutination
Biochemistry
2012
51(26):5329-38
PubMed ID: 22647083
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19252
Okada M, Nakajima K, Yaoita Y.
Translational regulation by the 5'-UTR of thyroid hormone receptor α mRNA
J Biochem
2012
151(5):519-31
PubMed ID: 22406405
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5626
Suzuki T, Nakano-Ikegaya M, Yabukami-Okuda H, de Hoon M, Severin J, Saga-Hatano S, Shin JW, Kubosaki A, Simon C, Hasegawa Y, Hayashizaki Y, Suzuki H.
Reconstruction of monocyte transcriptional regulatory network accompanies monocytic functions in human fibroblasts.
PLoS One
2012
7(3):e33474
PubMed ID: 22428058
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10938
Ayami Yamaguchi 1, Sae Tanaka, Shiho Yamaguchi, Hirokazu Kuwahara, Chizuko Takamura, Shinobu Imajoh-Ohmi, Daiki D Horikawa, Atsushi Toyoda, Toshiaki Katayama, Kazuharu Arakawa, Asao Fujiyama, Takeo Kubo, Takekazu Kunieda
Two Novel Heat-Soluble Protein Families Abundantly Expressed in an Anhydrobiotic Tardigrade
PLoS One
2012
7(8):e44209
PubMed ID: 22937162
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15731
Nishimura T, Honda H, Takeichi M.
Planar cell polarity links axes of spatial dynamics in neural-tube closure
Cell
2012
149(5):1084-97
PubMed ID: 22632972
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16569
Ooe H, Chen Q, Kon J, Sasaki K, Miyoshi H, Ichinohe N, Tanimizu N, Mitaka T.
Proliferation of rat small hepatocytes requires follistatin expression
J Cell Physiol
2012
227(6):2363-70
PubMed ID: 21826650
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16592
Li Y, Mitsuhashi S, Ikejo M, Miura N, Kawamura T, Hamakubo T, Ubukata M.
Relationship between ATM and ribosomal protein S6 revealed by the chemical inhibition of Ser/Thr protein phosphatase type 1
Biosci Biotechnol Biochem
2012
76(3):486-94
PubMed ID: 22451389
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16631
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Optogenetic inhibition of Purkinje cell activity reveals cerebellar control of blood pressure during postural alterations in anesthetized rats
Neuroscience .
2012
210:137-44
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18252
Horibe T, Kohno M, Haramoto M, Ohara K, Kawakami K.
Designed hybrid TPR peptide targeting Hsp90 as a novel anticancer agent
J Transl Med
2011
9:8
PubMed ID: 21235734
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7710
Sakaguchi T, Irie T, Kuwayama M, Ueno T, Yoshida A, Kawabata R.
Analysis of interaction of Sendai virus V protein and melanoma differentiation-associated gene 5.
Microbiol. Immunol.
2011
55:760-7
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7914
Jin ZB, Okamoto S, Osakada F, Homma K, Assawachananont J, Hirami Y, Iwata T, Takahashi M.
Modeling retinal degeneration using patient-specific induced pluripotent stem cells.
PLoS ONE
2011
6:e17084
PubMed ID: 21347327
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7970
Narukawa M, Noga C, Ueno Y, Sato T, Misaka T, Watanabe T.
Evaluation of the bitterness of green tea catechins by a cell-based assay with the human bitter taste receptor hTAS2R39.
Biochem. Biophys. Res. Commun.
2011
405:620-5
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12293
Ayako Kataoka, Yui Koga, Ayumi Uesugi, Hidetoshi Tozaki-Saitoh, Makoto Tsuda, Kazuhide Inoue
Involvement of vasodilator-stimulated phosphoprotein in UDP-induced microglial actin aggregation via PKC- and Rho-dependent pathways
Purinergic Signal
2011
7(4):403-11
PubMed ID: 21567128
DOI: 10.1007/s11302-011-9237-8
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15723
Sasaki M, Kawahara K, Nishio M, Mimori K, Kogo R, Hamada K, Itoh B, Wang J, Komatsu Y, Yang YR, Hikasa H, Horie Y, Yamashita T, Kamijo T, Zhang Y, Zhu Y, Prives C, Nakano T, Mak TW, Sasaki T, Maehama T, Mori M, Suzuki A.
Regulation of the MDM2-P53 pathway and tumor growth by PICT1 via nucleolar RPL11
Nat Med
2011
17(8):944-51
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8223
Mimasu S, Umezawa N, Sato S, Higuchi T, Umehara T, Yokoyama S.
Structurally designed trans-2-phenylcyclopropylamine derivatives potently inhibit histone demethylase LSD1/KDM1 .
Biochemistry
2010
49:6494-503
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8240
Naoe H, Araki K, Nagano O, Kobayashi Y, Ishizawa J, Chiyoda T, Shimizu T, Yamamura K, Sasaki Y, Saya H, Kuninaka S.
The anaphase-promoting complex/cyclosome activator Cdh1 modulates Rho GTPase by targeting p190 RhoGAP for degradation.
Mol. Cell. Biol.
2010
30:3994-4005
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Shigemura T, Shiohara M, Tanaka M, Takeuchi K, Koike K.
Effect of the mutant microphthalmia-associated transcription factor found in Tietz syndrome on the in vitro development of mast cells.
J. Pediatr. Hematol. Oncol.
2010
32:442-7
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19084
Oba M, Vachutinsky Y, Miyata K, Kano MR, Ikeda S, Nishiyama N, Itaka K, Miyazono K, Koyama H, Kataoka K.
Antiangiogenic gene therapy of solid tumor by systemic injection of polyplex micelles loading plasmid DNA encoding soluble flt-1
Mol Pharm
2010
7(2):501-9.
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3732
Niino Y, Hotta K, Oka K.
Blue fluorescent cGMP sensor for multiparameter fluorescence imaging
PLoS One
2010
5(2):e9164
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8531
Yamatoya K, Yoshida K, Ito C, Maekawa M, Yanagida M, Takamori K, Ogawa H, Araki Y, Miyado K, Toyama Y, Toshimori K.
Equatorin: identification and characterization of the epitope of the MN9 antibody in the mouse.
Biol. Reprod.
2009
81:889-97
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18454
Seto M, Ohta M, Asaoka Y, Ikenoue T, Tada M, Miyabayashi K, Mohri D, Tanaka Y, Ijichi H, Tateishi K, Kanai F, Kawabe T, Omata M.
Regulation of the hedgehog signaling by the mitogen-activated protein kinase cascade in gastric cancer
Mol Carcinog
2009
48(8):703-12
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11019
Shoudai Furuyama, Yoshinari Uehara, Bo Zhang, Yasuhiko Baba, Satomi Abe, Takahiro Iwamoto, Shin-Ichiro Miura, Keijiro Saku
Genotypic Effect of ABCG1 gene promoter -257T>G polymorphism on coronary artery disease severity in Japanese men
J Atheroscler Thromb
2009
16(3):194-200
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11002
Hiroyuki Oshiumi 1, Yuzuru Suzuki, Misako Matsumoto, Tsukasa Seya
Regulator of complement activation (RCA) gene cluster in Xenopus tropicalis
Immunogenetics
2009
61(5):371-84
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18690
Hata K, Koseki K, Yamaguchi K, Moriya S, Suzuki Y, Yingsakmongkon S, Hirai G, Sodeoka M, von Itzstein M, Miyagi T.
Limited inhibitory effects of oseltamivir and zanamivir on human sialidases
Antimicrob Agents Chemother
2008
52(10):3484-91
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19201
Suzuki T, Tsutsumi A, Suzuki H, Suzuki E, Sugihara M, Muraki Y, Hayashi T, Chino Y, Goto D, Matsumoto I, Ito S, Miyazawa K, Sumida T.
Tristetraprolin (TTP) gene polymorphisms in patients with rheumatoid arthritis and healthy individuals
Mod Rheumatol
2008
18(5):472-9
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4887
Satoh T, Arii J, Suenaga T, Wang J, Kogure A, Uehori J, Arase N, Shiratori I, Tanaka S, Kawaguchi Y, Spear PG, Lanier LL, Arase H.
PILRalpha is a herpes simplex virus-1 entry coreceptor that associates with glycoprotein B.
Cell
2008
132(6):935-44
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9071
Shiori Haga, Norio Yamamoto, Chikako Nakai-Murakami, Yoshiaki Osawa, Kenzo Tokunaga, Tetsutaro Sata, Naoki Yamamoto, Takehiko Sasazuki, Yukihito Ishizaka
Modulation of TNF-alpha-converting Enzyme by the Spike Protein of SARS-CoV and ACE2 Induces TNF-alpha Production and Facilitates Viral Entry
Proc Natl Acad Sci U S A
2008
105 (22), 7809-14
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12783
Ueno K, Hiura M, Suehiro Y, Hazama S, Hirata H, Oka M, Imai K, Dahiya R, Hinoda Y.
Frizzled-7 as a potential therapeutic target in colorectal cancer
Neoplasia
2008
10(7):697-705
PubMed ID: 18592008
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18701
Tateishi K, Ohta M, Kanai F, Guleng B, Tanaka Y, Asaoka Y, Tada M, Seto M, Jazag A, Lianjie L, Okamoto M, Isayama H, Tada M, Yoshida H, Kawabe T, Omata M.
Dysregulated expression of stem cell factor Bmi1 in precancerous lesions of the gastrointestinal tract
Clin Cancer Res
2006
12(23):6960-6
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6478
Nakatani S, Mano H, Ryanghyok IM, Shimizu J, Wada M.
Excess magnesium inhibits excess calcium-induced matrix-mineralization and production of matrix gla protein (MGP) by ATDC5 cells.
Biochem Biophys Res Commun
2006
348(3):1157-62
PubMed ID: 16904632
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