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12798
Johmura Y, Yamanaka T, Omori S, Wang TW, Sugiura Y, Matsumoto M, Suzuki N, Kumamoto S, Yamaguchi K, Hatakeyama S, Takami T, Yamaguchi R, Shimizu E, Ikeda K, Okahashi N, Mikawa R, Suematsu M, Arita M, Sugimoto M, Nakayama KI, Furukawa Y, Imoto S, Nakanishi M.
Senolysis by glutaminolysis inhibition ameliorates various age-associated disorders
Science
2021
371(6526):265-270
PubMed ID: 33446552
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13345
Daifu T, Mikami M, Hiramatsu H, Iwai A, Umeda K, Noura M, Kubota H, Masuda T, Furuichi K, Takasaki S, Noguchi Y, Morita K, Bando T, Hirata M, Kataoka TR, Nakahata T, Kuwahara Y, Iehara T, Hosoi H, Takita J, Sugiyama H, Adachi S, Kamikubo Y.
Suppression of malignant rhabdoid tumors through Chb-M'-mediated RUNX1 inhibition.
Pediatr Blood Cancer
2021
PubMed ID: 33180377
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13463
Shota Someya et al
Tryptophan Metabolism Regulates Proliferative Capacity of Human Pluripotent Stem Cells
iScienc
2021
24
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20008
Umaba R, Kitanishi T, Mizuseki K.
Monosynaptic connection from the subiculum to medial mammillary nucleus neurons projecting to the anterior thalamus and Gudden's ventral tegmental nucleus.
Neurosci Res
2021
PubMed ID: 33476683
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6889
Iuchi K, Oya K, Hosoya K, Sasaki K, Sakurada Y, Nakano T, Hisatomi H.
Different morphologies of human embryonic kidney 293T cells in various types of culture dishes.
Cytotechnology
2020
72(1):131-140
PubMed ID: 31865498
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9912
Hiroshi Suzuki, Yuichi Ozaki, Shigeho Ijiri, Koichiro Gen, Yukinori Kazeto
17β-Hydroxysteroid Dehydrogenase Type 12a Responsible for Testicular 11-ketotestosterone Synthesis in the Japanese Eel, Anguilla Japonica
J Steroid Biochem Mol Biol
2020
198:105550
PubMed ID: 31778803
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10370
Yusuke Higuchi, Jun-Ichirou Yasunaga, Yu Mitagami, Hirotake Tsukamoto, Kazutaka Nakashima, Koichi Ohshima, Masao Matsuoka
HTLV-1 Induces T Cell Malignancy and Inflammation by Viral Antisense Factor-Mediated Modulation of the Cytokine Signaling
Proc Natl Acad Sci U S A
2020
117(24):13740-13749
PubMed ID: 32471947
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11927
Yang J, Isaji T, Zhang G, Qi F, Duan C, Fukuda T, Gu J.
EpCAM associates with integrin and regulates cell adhesion in cancer cells.
Biochem. Biophys. Res. Commun.
2020
PubMed ID: 31806375
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11944
Qi F, Isaji T, Duan C, Yang J, Wang Y, Fukuda T, Gu J.
ST3GAL3, ST3GAL4, and ST3GAL6 differ in their regulation of biological functions via the specificities for the α2,3-sialylation of target proteins.
FASEB J.
2020
PubMed ID: 31914669
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11952
Kimura R, Yoshimaru T, Matsushita Y, Matsuo T, Ono M, Park JH, Sasa M, Miyoshi Y, Nakamura Y, Katagiri T.
The GALNT6‑LGALS3BP axis promotes breast cancer cell growth.
Int. J. Oncol.
2020
PubMed ID: 31894262
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11958
Hou S, Hang Q, Isaji T, Fukuda T, Gu J.
Identification of the minimal N-glycosylation on integrin α5β1 required for its inhibitory effect on EGFR signaling and cell proliferation.
Biochem. Biophys. Res. Commun.
2020
PubMed ID: 31858971
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11990
Duan C, Fukuda T, Isaji T, Qi F, Yang J, Wang Y, Takahashi S, Gu J.
Deficiency of core fucosylation activates cellular signaling dependent on FLT3 expression in a Ba/F3 cell system.
FASEB J.
2020
PubMed ID: 31908039
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12005
Kabayama H, Takeuchi M, Tokushige N, Muramatsu SI, Kabayama M, Fukuda M, Yamada Y, Mikoshiba K.
An ultra-stable cytoplasmic antibody engineered for in vivo applications.
Nat Commun
2020
PubMed ID: 31953402
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12015
Yamamoto H, Kon T, Omori Y, Furukawa T.
Functional and Evolutionary Diversification of Otx2 and Crx in Vertebrate Retinal Photoreceptor and Bipolar Cell Development.
Cell Rep
2020
PubMed ID: 31968244
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12027
Momoi Y, Nishikimi A, Du G, Kataoka T, Katagiri K.
Phosphatidic acid regulates subcellular distribution of RA-GEFs critical for chemokine-dependent migration.
Biochem. Biophys. Res. Commun.
2020
PubMed ID: 31996307
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12028
Iuchi K, Tasaki Y, Shirai S, Hisatomi H.
Upregulation of nuclear factor (erythroid-derived 2)-like 2 protein level in the human colorectal adenocarcinoma cell line DLD-1 by a heterocyclic organobismuth(III) compound: Effect of organobismuth(III) compound on NRF2 signaling.
Biomed. Pharmacother.
2020
PubMed ID: 32004978
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12086
Honda A, Chigwechokha PK, Takase R, Hayasaka O, Fujimura K, Kotani T, Komatsu M, Shiozaki K.
Novel Nile tilapia Neu1 sialidases: Molecular cloning and biochemical characterization of the sialidases Neu1a and Neu1b.
Gene
2020
PubMed ID: 32184168
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12096
Funakoshi-Tago M, Yu S, Kushida A, Takeuchi K, Tamura H.
Kampo medicines, Rokumigan, Hachimijiogan, and Goshajinkigan, significantly inhibit glucagon-induced CREB activation.
Heliyon
2020
PubMed ID: 32215330
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12129
Mutai H, Wasano K, Momozawa Y, Kamatani Y, Miya F, Masuda S, Morimoto N, Nara K, Takahashi S, Tsunoda T, Homma K, Kubo M, Matsunaga T.
Variants encoding a restricted carboxy-terminal domain of SLC12A2 cause hereditary hearing loss in humans.
PLoS Genet.
2020
PubMed ID: 32294086
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12364
Liu X, Tajima N, Taniguchi M, Kato N.
The enantiomer pair of 24S- and 24R-hydroxycholesterol differentially alter activity of large-conductance Ca 2+ -dependent K + (slo1 BK) channel
Chirality
2020
32(2):223-230
PubMed ID: 31756018
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12487
Yafei Liu et al
An infectivity-enhancing site on the SARS-CoV-2 spike protein is targeted by COVID-19 patient antibodies
bioRxiv
2020
December 18
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13019
Matsuzaki M, Mandai M, Yamanari M, Totani K, Nishida M, Sugita S, Maeda T, Koide N, Takagi S, Hirami Y, Miyamoto N, Sugiyama S, Takahashi M, Kurimoto Y.
Polarization-sensitive optical coherence tomography for estimating relative melanin content of autologous induced stem-cell derived retinal pigment epithelium.
Sci Rep
2020
PubMed ID: 32376945
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13020
Koshizuka T, Inoue N.
Activation of c-Jun by human cytomegalovirus UL42 through JNK activation.
PLoS One
2020
PubMed ID: 32369499
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13024
Kanoh H, Nitta T, Go S, Inamori KI, Veillon L, Nihei W, Fujii M, Kabayama K, Shimoyama A, Fukase K, Ohto U, Shimizu T, Watanabe T, Shindo H, Aoki S, Sato K, Nagasaki M, Yatomi Y, Komura N, Ando H, Ishida H, Kiso M, Natori Y, Yoshimura Y, Zonca A, Cattaneo A, Letizia M, Ciampa M, Mauri L, Prinetti A, Sonnino S, Suzuki A, Inokuchi JI.
Homeostatic and pathogenic roles of GM3 ganglioside molecular species in TLR4 signaling in obesity.
EMBO J
2020
PubMed ID: 32378734
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13028
Kido K, Yamanaka S, Nakano S, Motani K, Shinohara S, Nozawa A, Kosako H, Ito S, Sawasaki T.
AirID, a novel proximity biotinylation enzyme, for analysis of protein-protein interactions.
Elife
2020
PubMed ID: 32391793
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13034
Bajkowska K, Sumardika IW, Tomonobu N, Chen Y, Yamamoto KI, Kinoshita R, Murata H, Gede Yoni Komalasari NL, Jiang F, Yamauchi A, Winarsa Ruma IM, Kasano-Camones CI, Inoue Y, Sakaguchi M.
Neuroplastinβ-mediated upregulation of solute carrier family 22 member 18 antisense (SLC22A18AS) plays a crucial role in the epithelial-mesenchymal transition, leading to lung cancer cells' enhanced motility.
Biochem Biophys Rep
2020
PubMed ID: 32490214
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13044
Park M, Miyoshi C, Fujiyama T, Kakizaki M, Ikkyu A, Honda T, Choi J, Asano F, Mizuno S, Takahashi S, Yanagisawa M, Funato H.
Loss of the conserved PKA sites of SIK1 and SIK2 increases sleep need.
Sci Rep
2020
PubMed ID: 32457359
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13074
Horinouchi T, Yamamura T, Minamikawa S, Nagano C, Sakakibara N, Nakanishi K, Shima Y, Morisada N, Ishiko S, Aoto Y, Nagase H, Takeda H, Rossanti R, Ishimori S, Kaito H, Matsuo M, Iijima K, Nozu K.
Pathogenic evaluation of synonymous COL4A5 variants in X-linked Alport syndrome using a minigene assay.
Mol Genet Genomic Med
2020
PubMed ID: 32543079
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13080
Ito F, Yanatori I, Maeda Y, Nimura K, Ito S, Hirayama T, Nagasawa H, Kohyama N, Okazaki Y, Akatsuka S, Toyokuni S.
Asbestos conceives Fe(II)-dependent mutagenic stromal milieu through ceaseless macrophage ferroptosis and β-catenin induction in mesothelium.
Redox Biol
2020
PubMed ID: 32863225
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13164
Yamashita J, Takeuchi A, Hosono K, Fleming T, Nagahama Y, Okubo K.
Male-predominant galanin mediates androgen-dependent aggressive chases in medaka.
Elife
2020
PubMed ID: 32783809
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13182
Ishibashi R, Abe K, Ido N, Kitano S, Miyachi H, Toyoshima F.
Genome editing with the donor plasmid equipped with synthetic crRNA-target sequence.
Sci Rep
2020
PubMed ID: 32839482
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13186
Huetter J, Gritzan U, Gutcher I, Doecke WD, Luetke-Eversloh MV, Golfier S, Roider HG, Frisk AL, Hunter J, Pow A, Drake A, Levine Z, Levy O, Azulay M, Barbiro I, Cojocaru G, Vaknin I, Kreft B, Roese L.
Characterization of BAY 1905254, an Immune Checkpoint Inhibitor Targeting the Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2).
Cancer Immunol Res
2020
PubMed ID: 32312711
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13199
Kakizawa S, Kishimoto Y, Yamamoto S, Onga K, Yasuda K, Miyamoto Y, Watanabe M, Sakai R, Mori N.
Functional maintenance of calcium store by ShcB adaptor protein in cerebellar Purkinje cells.
Sci Rep
2020
PubMed ID: 32879382
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13200
Ago Y, Otsuka H, Sasai H, Abdelkreem E, Nakama M, Aoyama Y, Matsumoto H, Fujiki R, Ohara O, Akiyama K, Fukui K, Watanabe Y, Nakajima Y, Ohnishi H, Ito T, Fukao T.
Japanese patients with mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase deficiency: In vitro functional analysis of five novel HMGCS2 mutations.
Exp Ther Med
2020
PubMed ID: 32952630
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13204
Kinoshita N, Huang AJY, McHugh TJ, Miyawaki A, Shimogori T.
Diffusible GRAPHIC to visualize morphology of cells after specific cell-cell contact.
Sci Rep
2020
PubMed ID: 32879377
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13212
Kitao T, Taguchi K, Seto S, Arasaki K, Ando H, Nagai H, Kubori T.
Legionella Manipulates Non-canonical SNARE Pairing Using a Bacterial Deubiquitinase.
Cell Rep
2020
PubMed ID: 32905772
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13276
Arai Y, Kawashita N, Elgendy EM, Ibrahim MS, Daidoji T, Ono T, Takagi T, Nakaya T, Matsumoto K, Watanabe Y.
PA Mutations Inherited during Viral Evolution Act Cooperatively To Increase Replication of Contemporary H5N1 Influenza Virus with an Expanded Host Range.
J Virol
2020
PubMed ID: 33028722
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13293
Okamura M, Shizu R, Abe T, Kodama S, Hosaka T, Sasaki T, Yoshinari K.
PXR Functionally Interacts with NF-κB and AP-1 to Downregulate the Inflammation-Induced Expression of Chemokine CXCL2 in Mice.
Cells
2020
PubMed ID: 33076328
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13320
Matsumoto N, Sekiya M, Fujimoto Y, Haga S, Sun-Wada GH, Wada Y, Nakanishi-Matsui M.
Functional complementation of V-ATPase a subunit isoforms in osteoclasts.
J Biochem
2020
PubMed ID: 33135054
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13321
Kato M, Onoyama I, Kawakami M, Yoshida S, Kawamura K, Kodama K, Hori E, Cui L, Matsumura Y, Yagi H, Asanoma K, Yahata H, Itakura A, Takeda S, Kato K.
Downregulation of 5-hydroxymethylcytosine is associated with the progression of cervical intraepithelial neoplasia.
PLoS One
2020
PubMed ID: 33141854
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13327
Yamazaki T, Takahashi C, Taniguchi Y, Narukawa M, Misaka T, Ano Y.
Bitter taste receptor activation by hop-derived bitter components induces gastrointestinal hormone production in enteroendocrine cells.
Biochem Biophys Res Commun
2020
PubMed ID: 33160623
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13330
Osakabe K, Wada N, Miyaji T, Murakami E, Marui K, Ueta R, Hashimoto R, Abe-Hara C, Kong B, Yano K, Osakabe Y.
Genome editing in plants using CRISPR type I-D nuclease.
Commun Biol
2020
3(1):648
PubMed ID: 33159140
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11179
Ali F, Hossain MS, Sejimo S, Akashi K.
Plasmalogens Inhibit Endocytosis of Toll-like Receptor 4 to Attenuate the Inflammatory Signal in Microglial Cells.
Mol. Neurobiol.
2019
56(5):3404-3419
PubMed ID: 30128650
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11244
Zhang G, Isaji T, Xu Z, Lu X, Fukuda T, Gu J.
N-acetylglucosaminyltransferase-I as a novel regulator of epithelial-mesenchymal transition.
FASEB J.
2019
PubMed ID: 30307765
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11273
Mizuno M, Miki R, Moriyama Y, Ushida T, Imai K, Niimi K, Nakano T, Tsuda H, Sumigama S, Yamamoto E, Senga T, Iwase A, Kikkawa F, Kotani T.
The role of E2F8 in the human placenta.
Mol Med Rep
2019
PubMed ID: 30387815
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11319
Nitta T, Kanoh H, Inamori KI, Suzuki A, Takahashi T, Inokuchi JI.
Globo-series glycosphingolipids enhance Toll-like receptor 4-mediated inflammation and play a pathophysiological role in diabetic nephropathy.
Glycobiology
2019
PubMed ID: 30476082
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11315
Arai Y, Ibrahim MS, Elgendy EM, Daidoji T, Ono T, Suzuki Y, Nakaya T, Matsumoto K, Watanabe Y.
Genetic Compatibility of Reassortants between Avian H5N1 and H9N2 Influenza Viruses with Higher Pathogenicity in Mammals.
J. Virol.
2019
PubMed ID: 30463961
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11355
Xu Z, Isaji T, Fukuda T, Wang Y, Gu J.
O-GlcNAcylation regulates integrin-mediated cell adhesion and migration via formation of focal adhesion complexes.
J. Biol. Chem.
2019
PubMed ID: 30587575
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11368
Suzuki N, Hirano K, Ogino H, Ochi H.
Arid3a regulates nephric tubule regeneration via evolutionarily conserved regeneration signal-response enhancers.
Elife
2019
PubMed ID: 30616715
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11404
Kataoka K, Miyoshi H, Sakata S, Dobashi A, Couronné L, Kogure Y, Sato Y, Nishida K, Gion Y, Shiraishi Y, Tanaka H, Chiba K, Watatani Y, Kakiuchi N, Shiozawa Y, Yoshizato T, Yoshida K, Makishima H, Sanada M, Onozawa M, Teshima T, Yoshiki Y, Ishida T, Suzuki K, Shimada K, Tomita A, Kato M, Ota Y, Izutsu K, Demachi-Okamura A, Akatsuka Y, Miyano S, Yoshino T, Gaulard P, Hermine O, Takeuchi K, Ohshima K, Ogawa S.
Frequent structural variations involving programmed death ligands in Epstein-Barr virus-associated lymphomas.
Leukemia
2019
PubMed ID: 30683910
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11416
Matsumoto N, Nakanishi-Matsui M.
Proton pumping V-ATPase inhibitor bafilomycin A1 affects Rab7 lysosomal localization and abolishes anterograde trafficking of osteoclast secretory lysosomes.
Biochem. Biophys. Res. Commun.
2019
PubMed ID: 30717974
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11418
Shimizu Y, Kohyama M, Yorifuji H, Jin H, Arase N, Suenaga T, Arase H.
FcγRIIIA-mediated activation of NK cells by IgG heavy chain complexed with MHC class II molecules.
Int. Immunol.
2019
PubMed ID: 30721990
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11430
Ishibashi D, Homma T, Nakagaki T, Fuse T, Sano K, Satoh K, Mori T, Atarashi R, Nishida N.
Type I interferon protects neurons from prions in in vivo models.
Brain
2019
PubMed ID: 30753318
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11475
Yorifuji H, Arase N, Kohyama M, Hirano T, Suenaga T, Kumanogoh A, Arase H.
Transport of cellular misfolded proteins to the cell surface by HLA-B27 free heavy chain.
Biochem. Biophys. Res. Commun.
2019
PubMed ID: 30850159
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11465
Sarkar B, Nishikata I, Nakahata S, Ichikawa T, Shiraga T, Saha HR, Fujii M, Tanaka Y, Shimoda K, Morishita K.
Degradation of p47 by autophagy contributes to CADM1 overexpression in ATLL cells through the activation of NF-κB.
Sci Rep
2019
PubMed ID: 30837480
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11490
Chen Y, Sumardika IW, Tomonobu N, Winarsa Ruma IM, Kinoshita R, Kondo E, Inoue Y, Sato H, Yamauchi A, Murata H, Yamamoto KI, Tomida S, Shien K, Yamamoto H, Soh J, Liu M, Futami J, Sasai K, Katayama H, Kubo M, Putranto EW, Hibino T, Sun B, Nishibori M, Toyooka S, Sakaguchi M.
Melanoma cell adhesion molecule is the driving force behind the dissemination of melanoma upon S100A8/A9 binding in the original skin lesion.
Cancer Lett.
2019
PubMed ID: 30904617
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5345
Yamaguchi S, Tanimoto A, Iwasa S, Otsuguro KI.
TRPM4 and TRPM5 Channels Share Crucial Amino Acid Residues for Ca2+ Sensitivity but Not Significance of PI(4,5)P2.
Int J Mol Sci
2019
20(8):2012
PubMed ID: 31022885
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6833
Yokoyama T, Machida K, Iwasaki W, Shigeta T, Nishimoto M, Takahashi M, Sakamoto A, Yonemochi M, Harada Y, Shigematsu H, Shirouzu M, Tadakuma H, Imataka H, Ito T.
HCV IRES Captures an Actively Translating 80S Ribosome.
Mol Cell
2019
74(6):1205-1214
PubMed ID: 31080011
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11500
Mizuta H, Kuga K, Suzuki T, Niwa Y, Dohmae N, Simizu S.
C‑mannosylation of R‑spondin2 activates Wnt/β‑catenin signaling and migration activity in human tumor cells.
Int. J. Oncol.
2019
PubMed ID: 30942431
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11520
Liu YY, Tanikawa C, Ueda K, Matsuda K.
INKA2, a novel p53 target that interacts with the serine/threonine kinase PAK4.
Int. J. Oncol.
2019
PubMed ID: 31081062
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11554
Matsubara H, Tanaka R, Tateishi T, Yoshida H, Yamaguchi M, Kataoka T.
The human Bcl-2 family member Bcl-rambo and voltage-dependent anion channels manifest a genetic interaction in Drosophila and cooperatively promote the activation of effector caspases in human cultured cells.
Exp. Cell Res.
2019
PubMed ID: 31102594
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11555
Chen Y, Sumardika IW, Tomonobu N, Kinoshita R, Inoue Y, Iioka H, Mitsui Y, Saito K, Ruma IMW, Sato H, Yamauchi A, Murata H, Yamamoto KI, Tomida S, Shien K, Yamamoto H, Soh J, Futami J, Kubo M, Putranto EW, Murakami T, Liu M, Hibino T, Nishibori M, Kondo E, Toyooka S, Sakaguchi M.
Critical role of the MCAM-ETV4 axis triggered by extracellular S100A8/A9 in breast cancer aggressiveness.
Neoplasia
2019
PubMed ID: 31100639
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11580
Tanaka J, Mabuchi Y, Hata K, Yasuhara R, Takamatsu K, Kujiraoka S, Yukimori A, Takakura I, Sumimoto H, Fukada T, Azuma M, Akiyama H, Nishimura R, Shimane T, Mishima K.
Sox9 regulates the luminal stem/progenitor cell properties of salivary glands.
Exp. Cell Res.
2019
PubMed ID: 31153924
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11621
Arai Y, Kawashita N, Ibrahim MS, Elgendy EM, Daidoji T, Ono T, Takagi T, Nakaya T, Matsumoto K, Watanabe Y.
PB2 mutations arising during H9N2 influenza evolution in the Middle East confer enhanced replication and growth in mammals.
PLoS Pathog.
2019
PubMed ID: 31265471
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11624
Furuse Y, Chaimongkol N, Okamoto M, Oshitani H.
Evolutionary and Functional Diversity of the 5' Untranslated Region of Enterovirus D68: Increased Activity of the Internal Ribosome Entry Site of Viral Strains during the 2010s.
Viruses
2019
PubMed ID: 31288421
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11643
Ishii J, Suzuki A, Kimura T, Tateyama M, Tanaka T, Yazawa T, Arimasu Y, Chen IS, Aoyama K, Kubo Y, Saitoh S, Mizuno H, Kamma H.
Congenital goitrous hypothyroidism is caused by dysfunction of the iodide transporter SLC26A7.
Commun Biol
2019
PubMed ID: 31372509
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11647
Wong JH, Shigemizu D, Yoshii Y, Akiyama S, Tanaka A, Nakagawa H, Narumiya S, Fujimoto A.
Identification of intermediate-sized deletions and inference of their impact on gene expression in a human population.
Genome Med
2019
PubMed ID: 31340865
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11716
Makino Y, Jensen NH, Yokota N, Rossner MJ, Akiyama H, Shirahige K, Okada Y.
Single cell RNA-sequencing identified Dec2 as a suppressive factor for spermatogonial differentiation by inhibiting Sohlh1 expression.
Sci Rep
2019
PubMed ID: 30988352
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11720
Yamanashi T, Maki M, Kojima K, Shibukawa A, Tsukamoto T, Chowdhury S, Yamanaka A, Takagi S, Sudo Y.
Quantitation of the neural silencing activity of anion channelrhodopsins in Caenorhabditis elegans and their applicability for long-term illumination.
Sci Rep
2019
PubMed ID: 31133660
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11766
Su Y, Nichuguti N, Kuroki-Kami A, Fujiwara H.
Sequence-specific retrotransposition of 28S rDNA-specific LINE R2Ol in human cells.
RNA
2019
PubMed ID: 31434792
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11845
Kamiki H, Matsugo H, Ishida H, Kobayashi-Kitamura T, Sekine W, Takenaka-Uema A, Murakami S, Horimoto T.
Adaptation of H3N2 canine influenza virus to feline cell culture.
PLoS ONE
2019
PubMed ID: 31600274
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11854
Yamamoto M, Terada Y, Motoyama T, Saito T, Ito K.
Sweet proteins lysozyme and thaumatin are protein-type agonists for the calcium-sensing receptor.
Biochem. Biophys. Res. Commun.
2019
PubMed ID: 31635806
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11855
Morita A, Aoshima K, Gulay KCM, Onishi S, Shibata Y, Yasui H, Kobayashi A, Kimura T.
High drug efflux pump capacity and low DNA damage response induce doxorubicin resistance in canine hemangiosarcoma cell lines.
Res. Vet. Sci.
2019
PubMed ID: 31648115
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6886
Musha S, Nagayama S, Murakami S, Kojima R, Deai M, Sato K, Okajima F, Ueharu H, Tomura H.
Protons Differentially Activate TDAG8 Homologs from Various Species.
Zoolog Sci
2019
36(2):105-111
PubMed ID: 31120644
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6931
Nakanishi M, Hino M, Yoshimura M, Amakura Y, Nomoto H.
Identification of sinensetin and nobiletin as major antitrypanosomal factors in a citrus cultivar.
Exp Parasitol
2019
200:24-29
PubMed ID: 30898543
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9468
Kazuyo Fujita, Masaharu Somiya, Shun'ichi Kuroda, Shuji Hinuma
Induction of Lipid Droplets in Non-Macrophage Cells as Well as Macrophages by Liposomes and Exosomes
Biochem Biophys Res Commun
2019
510(1):184-190
PubMed ID: 30678809
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11909
Sakaue T, Hamaguchi M, Aono J, Nakashiro KI, Shikata F, Kawakami N, Oshima Y, Kurata M, Nanba D, Masumoto J, Yamaguchi O, Higashiyama S, Izutani H.
Valve Interstitial Cell-Specific Cyclooxygenase-1 Associated With Calcification of Aortic Valves.
Ann. Thorac. Surg.
2019
PubMed ID: 31760051
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11700
Uchibori R, Teruya T, Ido H, Ohmine K, Sehara Y, Urabe M, Mizukami H, Mineno J, Ozawa K.
Functional Analysis of an Inducible Promoter Driven by Activation Signals from a Chimeric Antigen Receptor
Mol Ther Oncolytics
2019
2:16-25
PubMed ID: 30662937
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12285
Arisa Mitani, Takeshi Kobayashi, Yasuhito Hayashi, Natsuki Matsushita, Sachi Matsushita, Saori Nakao, Naoko Takahira, Atsushi Shiraishi, Yuichi Ohashi
Characterization of doxycycline-dependent inducible Simian Virus 40 large T antigen immortalized human conjunctival epithelial cell line
PLoS One
2019
14(9):e0222454
PubMed ID: 31509592
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12299
Nobuyoshi Tajima, Liu Xiaoyan, Makoto Taniguchi, Nobuo Kato
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FEBS Open Bio
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BMC Nephrol
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Biosci Biotechnol Biochem
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PLoS One
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Nature
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Hagiwara A, Ogiwara K, Takahashi T.
Expression of Membrane Progestin Receptors (mPRs) in Granulosa Cells of Medaka Preovulatory Follicles.
Zool. Sci.
2016
33:98-105
PubMed ID: 26853875
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9627
Koguchi T, Tanikawa C, Mori J, Kojima Y, Matsuda K.
Regulation of myo-inositol biosynthesis by p53-ISYNA1 pathway.
Int. J. Oncol.
2016
48:2415-24
PubMed ID: 27035231
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9649
Tsuchiya M, Niwa Y, Simizu S.
N-glycosylation of R-spondin1 at Asn137 negatively regulates its secretion and Wnt/β-catenin signaling-enhancing activity.
Oncol Lett
2016
11:3279-3286
PubMed ID: 27123103
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9664
Tanaka H, Fujiwara H, Ochi F, Tanimoto K, Casey N, Okamoto S, Mineno J, Kuzushima K, Shiku H, Sugiyama T, Barrett AJ, Yasukawa M.
Development of Engineered T Cells Expressing a Chimeric CD16-CD3ζ Receptor to Improve the Clinical Efficacy of Mogamulizumab Therapy Against Adult T-Cell Leukemia.
Clin. Cancer Res.
2016
22:4405-16
PubMed ID: 27091408
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9671
Hirayasu K, Saito F, Suenaga T, Shida K, Arase N, Oikawa K, Yamaoka T, Murota H, Chibana H, Nakagawa I, Kubori T, Nagai H, Nakamaru Y, Katayama I, Colonna M, Arase H.
Microbially cleaved immunoglobulins are sensed by the innate immune receptor LILRA2.
Nat Microbiol
2016
1:16054
PubMed ID: 27572839
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9783
Khanom R, Nguyen CT, Kayamori K, Zhao X, Morita K, Miki Y, Katsube K, Yamaguchi A, Sakamoto K.
Keratin 17 Is Induced in Oral Cancer and Facilitates Tumor Growth.
PLoS ONE
2016
11:e0161163
PubMed ID: 27512993
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9793
Yamaura K, Kiyonaka S, Numata T, Inoue R, Hamachi I.
Discovery of allosteric modulators for GABAA receptors by ligand-directed chemistry.
Nat. Chem. Biol.
2016
12:822-30
PubMed ID: 27526031
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9807
Kobayashi T, Yagi Y, Nakamura T.
Development of Genome Engineering Tools from Plant-Specific PPR Proteins Using Animal Cultured Cells.
Methods Mol. Biol.
2016
1469:147-55
PubMed ID: 27557692
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9843
Kondoh Y, Honda K, Hiranuma S, Hayashi T, Shimizu T, Watanabe N, Osada H.
Comparative chemical array screening for p38γ/δ MAPK inhibitors using a single gatekeeper residue difference between p38α/β and p38γ/δ.
Sci Rep
2016
6:29881
PubMed ID: 27431267
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9845
Hazawa M, Yasuda T, Saotome-Nakamura A, Tomiyama K, Obara C, Goto T, Tajima K.
Intra- and extracellular plasminogen activator inhibitor-1 regulate effect of vitronectin against radiation-induced endothelial cell death.
Vascul. Pharmacol.
2016
87:150-158
PubMed ID: 27650166
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9846
Hang Q, Isaji T, Hou S, Zhou Y, Fukuda T, Gu J.
N-Glycosylation of integrin α5 acts as a switch for EGFR-mediated complex formation of integrin α5β1 to α6β4.
Sci Rep
2016
6:33507
PubMed ID: 27641064
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9908
Kurita K, Maeda M, Mansour MA, Kokuryo T, Uehara K, Yokoyama Y, Nagino M, Hamaguchi M, Senga T.
TRIP13 is expressed in colorectal cancer and promotes cancer cell invasion.
Oncol Lett
2016
12:5240-5246
PubMed ID: 28105232
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9916
Nishimura T, Ito S, Saito H, Hiver S, Shigetomi K, Ikenouchi J, Takeichi M.
DAAM1 stabilizes epithelial junctions by restraining WAVE complex-dependent lateral membrane motility.
J. Cell Biol.
2016
215:559-573
PubMed ID: 27807130
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10012
Ohtsuka T, Sakaguchi M, Yamamoto H, Tomida S, Takata K, Shien K, Hashida S, Miyata-Takata T, Watanabe M, Suzawa K, Soh J, Youyi C, Sato H, Namba K, Torigoe H, Tsukuda K, Yoshino T, Miyoshi S, Toyooka S.
Interaction of cytokeratin 19 head domain and HER2 in the cytoplasm leads to activation of HER2-Erk pathway.
Sci Rep
2016
6:39557
PubMed ID: 28008968
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10015
Hirayama S, Hori Y, Benedek Z, Suzuki T, Kikuchi K.
Fluorogenic probes reveal a role of GLUT4 N-glycosylation in intracellular trafficking.
Nat. Chem. Biol.
2016
12:853-9
PubMed ID: 27547921
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10016
Hou S, Hang Q, Isaji T, Lu J, Fukuda T, Gu J.
Importance of membrane-proximal N-glycosylation on integrin β1 in its activation and complex formation.
FASEB J.
2016
30:4120-4131
PubMed ID: 27565712
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12288
Kung-Kai Kuo, King-Teh Lee, Ker-Kong Chen, Ya-Han Yang, Ying-Chu Lin, Ming-Ho Tsai, Kenly Wuputra, Yen-Liang Lee, Chia-Chen Ku, Hiroyuki Miyoshi, Yukio Nakamura, Shigeo Saito, Chun-Chieh Wu, Chee-Yin Chai, Richard Eckner, Chen-Lung Steve Lin, Sophie S-W Wang, Deng-Chyang Wu, Chang-Shen Lin, Kazunari K Yokoyama
Positive Feedback Loop of OCT4 and c-JUN Expedites Cancer Stemness in Liver Cancer
Stem Cells
2016
34(11):2613-2624
PubMed ID: 27341307
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12627
Elmansuri AZ, Tanino MA, Mahabir R, Wang L, Kimura T, Nishihara H, Kinoshita I, Dosaka-Akita H, Tsuda M, Tanaka S.
Novel signaling collaboration between TGF-β and adaptor protein Crk facilitates EMT in human lung cancer
Oncotarget
2016
7(19):27094-107
PubMed ID: 27027347
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12670
Mori J, Tanikawa C, Funauchi Y, Lo PH, Nakamura Y, Matsuda K.
Cystatin C as a p53-inducible apoptotic mediator that regulates cathepsin L activity
Cancer Sci
2016
107(3):298-306
PubMed ID: 26757339
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12671
Lu J, Isaji T, Im S, Fukuda T, Kameyama A, Gu J.
Expression of N-Acetylglucosaminyltransferase III Suppresses α2,3-Sialylation, and Its Distinctive Functions in Cell Migration Are Attributed to α2,6-Sialylation Levels
J Biol Chem
2016
291(11):5708-20
PubMed ID: 26801611
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12894
Sohn J, Okamoto S, Kataoka N, Kaneko T, Nakamura K, Hioki H.
Differential Inputs to the Perisomatic and Distal-Dendritic Compartments of VIP-Positive Neurons in Layer 2/3 of the Mouse Barrel Cortex
Front Neuroanat
2016
10:124
PubMed ID: 28066195
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12923
Ryuzono S, Takase R, Oishi K, Ikeda A, Chigwechokha PK, Funahashi A, Komatsu M, Miyagi T, Shiozaki K.
Lysosomal localization of Japanese medaka (Oryzias latipes) Neu1 sialidase and its highly conserved enzymatic profiles with human
Gene
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575(2 Pt 2):513-523.
PubMed ID: 26432003
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12933
Obayashi M, Yoshida M, Tsunematsu T, Ogawa I, Sasahira T, Kuniyasu H, Imoto I, Abiko Y, Xu D, Fukunaga S, Tahara H, Kudo Y, Nagao T, Takata T.
microRNA-203 suppresses invasion and epithelial-mesenchymal transition induction via targeting NUAK1 in head and neck cancer
Oncotarget
2016
7(7):8223-39
PubMed ID: 26882562
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13460
Miyake T, Kumasawa K, Sato N, Takiuchi T, Nakamura H, Kimura T.
Soluble VEGF receptor 1 (sFLT1) induces non-apoptotic death in ovarian and colorectal cancer cells
Sci Rep
2016
6:24853
PubMed ID: 27103202
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13471
Wang SS, Wuputra K, Liu CJ, Lin YC, Chen YT, Chai CY, Lin CS, Kuo KK, Tsai MH, Wang SW, Chen KK, Miyoshi H, Nakamura Y, Saito S, Hanafusa T, Wu DC, Lin CS, Yokoyama KK.
Oncogenic function of the homeobox A13-long noncoding RNA HOTTIP-insulin growth factor-binding protein 3 axis in human gastric cancer
Oncotarget
2016
7(24):36049-36064
PubMed ID: 27144338
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7180
Hang Q, Isaji T, Hou S, Im S, Fukuda T, Gu J.
Integrin α5 Suppresses the Phosphorylation of Epidermal Growth Factor Receptor and Its Cellular Signaling of Cell Proliferation via N-Glycosylation.
J. Biol. Chem.
2015
290:29345-60
PubMed ID: 26483551
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7190
Kataoka K, Nagata Y, Kitanaka A, Shiraishi Y, Shimamura T, Yasunaga J, Totoki Y, Chiba K, Sato-Otsubo A, Nagae G, Ishii R, Muto S, Kotani S, Watatani Y, Takeda J, Sanada M, Tanaka H, Suzuki H, Sato Y, Shiozawa Y, Yoshizato T, Yoshida K, Makishima H, Iwanaga M, Ma G, Nosaka K, Hishizawa M, Itonaga H, Imaizumi Y, Munakata W, Ogasawara H, Sato T, Sasai K, Muramoto K, Penova M, Kawaguchi T, Nakamura H, Hama N, Shide K, Kubuki Y, Hidaka T, Kameda T, Nakamaki T, Ishiyama K, Miyawaki S, Yoon SS, Tobinai K, Miyazaki Y, Takaori-Kondo A, Matsuda F, Takeuchi K, Nureki O, Aburatani H, Watanabe T, Shibata T, Matsuoka M, Miyano S, Shimoda K, Ogawa S.
Integrated molecular analysis of adult T cell leukemia/lymphoma.
Nat. Genet.
2015
47:1304-15
PubMed ID: 26437031
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7216
Aoki N, Yamaguchi S, Kitajima T, Takehara A, Katagiri-Nakagawa S, Matsui R, Watanabe D, Matsushima T, Homma KJ.
Critical role of the neural pathway from the intermediate medial mesopallium to the intermediate hyperpallium apicale in filial imprinting of domestic chicks (Gallus gallus domesticus).
Neuroscience
2015
308:115-24
PubMed ID: 26362886
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7242
Okumura N, Minamiyama R, Ho LT, Kay EP, Kawasaki S, Tourtas T, Schlotzer-Schrehardt U, Kruse FE, Young RD, Quantock AJ, Kinoshita S, Koizumi N.
Involvement of ZEB1 and Snail1 in excessive production of extracellular matrix in Fuchs endothelial corneal dystrophy.
Lab. Invest.
2015
95:1291-304
PubMed ID: 26302187
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7252
Ichikawa T, Nakahata S, Fujii M, Iha H, Morishita K.
Loss of NDRG2 enhanced activation of the NF-κB pathway by PTEN and NIK phosphorylation for ATL and other cancer development.
Sci Rep
2015
5:12841
PubMed ID: 26269411
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7263
Ichikawa T, Nakahata S, Tamura T, Manachai N, Morishita K.
The loss of NDRG2 expression improves depressive behavior through increased phosphorylation of GSK3β.
Cell. Signal.
2015
27:2087-98
PubMed ID: 26208882
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7274
Tohmonda T, Yoda M, Iwawaki T, Matsumoto M, Nakamura M, Mikoshiba K, Toyama Y, Horiuchi K.
IRE1α/XBP1-mediated branch of the unfolded protein response regulates osteoclastogenesis.
J. Clin. Invest.
2015
125:3269-79
PubMed ID: 26193638
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7371
Kimura T, Endo S, Inui M, Saitoh S, Miyake K, Takai T.
Endoplasmic Protein Nogo-B (RTN4-B) Interacts with GRAMD4 and Regulates TLR9-Mediated Innate Immune Responses.
J. Immunol.
2015
194:5426-36
PubMed ID: 25917084
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7393
Ito T, Hioki H, Sohn J, Okamoto S, Kaneko T, Iino S, Oliver DL.
Convergence of Lemniscal and Local Excitatory Inputs on Large GABAergic Tectothalamic Neurons.
J. Comp. Neurol.
2015
523:2277-96
PubMed ID: 25879870
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7426
Nakazato R, Takarada T, Ikeno S, Nakamura S, Kutsukake T, Hinoi E, Yoneda Y.
Upregulation of Runt-Related Transcription Factor-2 Through CCAAT Enhancer Binding Protein-β Signaling Pathway in Microglial BV-2 Cells Exposed to ATP.
J. Cell. Physiol.
2015
230:2510-21
PubMed ID: 25802132
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7435
Ebina H, Kanemura Y, Misawa N, Sakuma T, Kobayashi T, Yamamoto T, Koyanagi Y.
A high excision potential of TALENs for integrated DNA of HIV-based lentiviral vector.
PLoS ONE
2015
10:e0120047
PubMed ID: 25781496
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7468
Masuda K, Chiyoda T, Sugiyama N, Segura-Cabrera A, Kabe Y, Ueki A, Banno K, Suematsu M, Aoki D, Ishihama Y, Saya H, Kuninaka S.
LATS1 and LATS2 phosphorylate CDC26 to modulate assembly of the tetratricopeptide repeat subcomplex of APC/C.
PLoS ONE
2015
10:e0118662
PubMed ID: 25723520
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7514
Mochimaru Y, Azuma M, Oshima N, Ichijo Y, Satou K, Matsuda K, Asaoka Y, Nishina H, Nakakura T, Mogi C, Sato K, Okajima F, Tomura H.
Extracellular acidification activates ovarian cancer G-protein-coupled receptor 1 and GPR4 homologs of zebra fish.
Biochem. Biophys. Res. Commun.
2015
457:493-9
PubMed ID: 25576873
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3744
Nakamura R, Oyama T, Tajiri R, Mizokami A, Namiki M, Nakamoto M, Ooi A.
Expression and regulatory effects on cancer cell behavior of NELL1 and NELL2 in human renal cell carcinoma.
Cancer Sci
2015
106(5):656-64
PubMed ID: 25726761
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9407
Michiko Yoshida, Kenji Hata, Rikako Takashima, Koichiro Ono, Eriko Nakamura, Yoshifumi Takahata, Tomohiko Murakami, Sachiko Iseki, Teruko Takano-Yamamoto, Riko Nishimura, Toshiyuki Yoneda
The Transcription Factor Foxc1 Is Necessary for Ihh-Gli2-regulated Endochondral Ossification
Nat Commun
2015
6:6653
PubMed ID: 25808752
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9488
Tadahiro Suenaga, Maki Matsumoto, Fuminori Arisawa, Masako Kohyama, Kouyuki Hirayasu, Yasuko Mori, Hisashi Arase
Sialic Acids on Varicella-Zoster Virus Glycoprotein B Are Required for Cell-Cell Fusion
J Biol Chem
2015
290(32):19833-43
PubMed ID: 26105052
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7579
Suzuki-Nakagawa C, Nishimura M, Tsukamoto T, Aoyama S, Ebihara A, Suzuki F, Nakagawa T.
Participation of the extracellular domain in (pro)renin receptor dimerization.
Biochem. Biophys. Res. Commun.
2014
444:461-6
PubMed ID: 24472541
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5836
Saito K, Sakaguchi M, Iioka H, Matsui M, Nakanishi H, Huh NH, Kondo E.
Coxsackie and adenovirus receptor is a critical regulator for the survival and growth of oral squamous carcinoma cells.
Oncogene
2014
33(10):1274-86
PubMed ID: 23503462
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6082
Ohnishi H, Sasaki H, Nakamura Y, Kato S, Ando K, Narimatsu H, Tachibana K.
Regulation of cell shape and adhesion by CD34
Cell Adh Migr
2013
7(5):426-33
PubMed ID: 24036614
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10938
Ayami Yamaguchi 1, Sae Tanaka, Shiho Yamaguchi, Hirokazu Kuwahara, Chizuko Takamura, Shinobu Imajoh-Ohmi, Daiki D Horikawa, Atsushi Toyoda, Toshiaki Katayama, Kazuharu Arakawa, Asao Fujiyama, Takeo Kubo, Takekazu Kunieda
Two Novel Heat-Soluble Protein Families Abundantly Expressed in an Anhydrobiotic Tardigrade
PLoS One
2012
7(8):e44209
PubMed ID: 22937162
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7627
Ohue Y, Eikawa S, Okazaki N, Mizote Y, Isobe M, Uenaka A, Fukuda M, Old LJ, Oka M, Nakayama E.
Spontaneous antibody, and CD4 and CD8 T-cell responses against XAGE-1b (GAGED2a) in non-small cell lung cancer patients.
Int. J. Cancer
2011
131:E649-58
PubMed ID: 22109656
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7710
Sakaguchi T, Irie T, Kuwayama M, Ueno T, Yoshida A, Kawabata R.
Analysis of interaction of Sendai virus V protein and melanoma differentiation-associated gene 5.
Microbiol. Immunol.
2011
55:760-7
PubMed ID: 21851384
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7970
Narukawa M, Noga C, Ueno Y, Sato T, Misaka T, Watanabe T.
Evaluation of the bitterness of green tea catechins by a cell-based assay with the human bitter taste receptor hTAS2R39.
Biochem. Biophys. Res. Commun.
2011
405:620-5
PubMed ID: 21272567
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12293
Ayako Kataoka, Yui Koga, Ayumi Uesugi, Hidetoshi Tozaki-Saitoh, Makoto Tsuda, Kazuhide Inoue
Involvement of vasodilator-stimulated phosphoprotein in UDP-induced microglial actin aggregation via PKC- and Rho-dependent pathways
Purinergic Signal
2011
7(4):403-11
PubMed ID: 21567128
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8223
Mimasu S, Umezawa N, Sato S, Higuchi T, Umehara T, Yokoyama S.
Structurally designed trans-2-phenylcyclopropylamine derivatives potently inhibit histone demethylase LSD1/KDM1 .
Biochemistry
2010
49:6494-503
PubMed ID: 20568732
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8240
Naoe H, Araki K, Nagano O, Kobayashi Y, Ishizawa J, Chiyoda T, Shimizu T, Yamamura K, Sasaki Y, Saya H, Kuninaka S.
The anaphase-promoting complex/cyclosome activator Cdh1 modulates Rho GTPase by targeting p190 RhoGAP for degradation.
Mol. Cell. Biol.
2010
30:3994-4005
PubMed ID: 20530197
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8251
Shigemura T, Shiohara M, Tanaka M, Takeuchi K, Koike K.
Effect of the mutant microphthalmia-associated transcription factor found in Tietz syndrome on the in vitro development of mast cells.
J. Pediatr. Hematol. Oncol.
2010
32:442-7
PubMed ID: 20485200
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11019
Shoudai Furuyama, Yoshinari Uehara, Bo Zhang, Yasuhiko Baba, Satomi Abe, Takahiro Iwamoto, Shin-Ichiro Miura, Keijiro Saku
Genotypic Effect of ABCG1 gene promoter -257T>G polymorphism on coronary artery disease severity in Japanese men
J Atheroscler Thromb
2009
16(3):194-200
PubMed ID: 19556716
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11002
Hiroyuki Oshiumi 1, Yuzuru Suzuki, Misako Matsumoto, Tsukasa Seya
Regulator of complement activation (RCA) gene cluster in Xenopus tropicalis
Immunogenetics
2009
61(5):371-84
PubMed ID: 19319518
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4887
Satoh T, Arii J, Suenaga T, Wang J, Kogure A, Uehori J, Arase N, Shiratori I, Tanaka S, Kawaguchi Y, Spear PG, Lanier LL, Arase H.
PILRalpha is a herpes simplex virus-1 entry coreceptor that associates with glycoprotein B.
Cell
2008
132(6):935-44
PubMed ID: 18358807
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9071
Shiori Haga, Norio Yamamoto, Chikako Nakai-Murakami, Yoshiaki Osawa, Kenzo Tokunaga, Tetsutaro Sata, Naoki Yamamoto, Takehiko Sasazuki, Yukihito Ishizaka
Modulation of TNF-alpha-converting Enzyme by the Spike Protein of SARS-CoV and ACE2 Induces TNF-alpha Production and Facilitates Viral Entry
Proc Natl Acad Sci U S A
2008
105 (22), 7809-14
PubMed ID: 18490652
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12783
Ueno K, Hiura M, Suehiro Y, Hazama S, Hirata H, Oka M, Imai K, Dahiya R, Hinoda Y.
Frizzled-7 as a potential therapeutic target in colorectal cancer
Neoplasia
2008
10(7):697-705
PubMed ID: 18592008
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6478
Nakatani S, Mano H, Ryanghyok IM, Shimizu J, Wada M.
Excess magnesium inhibits excess calcium-induced matrix-mineralization and production of matrix gla protein (MGP) by ATDC5 cells.
Biochem Biophys Res Commun
2006
348(3):1157-62
PubMed ID: 16904632
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