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細胞番号 : 細胞名
RCB2202 : 293T  update : 2021/08/13
細胞特性(Comment:英)A subline of 293. Expressing SV40 large T antigen.
細胞特性(日)293細胞株の亜株。SV40 large T 抗原を発現している。
細胞特性(寄託者記述:英)
細胞特性(寄託者記述:日)
使用条件(英)Can be used only by not-for-profit entities and only for not-for-profit academic purposes.
使用条件(日)非営利機関における非営利目的の研究にのみ使用が可能です。
備考(英)
備考(日)
提供申込書類(英) Order Form(C-0005.pdf)   MTA(C-0007.pdf)  
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
提供申込書類(日) 依頼書C-0001.pdf   同意書(非営利学術目的)C-0003.pdf  
提供同意書は、使用機関の種類や目的に応じて、非営利学術目的 (C-XXXX) と営利目的 (C-XXXXp) の2種類があります。該当する提供同意書をご使用ください(詳細)。特許等の取得及び商業利用等は事前に必ず(cellbank.brc@riken.jp)までご連絡ください。
提供手数料 手数料とお支払いについてはこちらをご覧ください。
細胞基本情報 寄託者 Miyoshi, Hiroyuki
寄託日 2005
元の細胞 HEK293
動物種 _human < Mammals
属名 Homo
種名 sapiens
embryo
採取組織 kidney
細胞分類 transformed
細胞寿命 infinite
細胞形態 epithelial-like
Cellosaurus(Expasy) CVCL_0063
細胞培養・検査情報
寄託時情報
ロット情報
培地・試薬情報 培地・試薬一覧はこちらをご覧ください。
培養形態 Adherent cells
培地 DMEM (low glucose) + 10% FBS (heat inactivated)
抗生物質 Free
継代方法 0.25% trypsin
継代密度 1 : 10 split
継代・培地交換頻度 Subculture : 2 times/week
培養最適温度 37 ℃
二酸化炭素濃度 5 %
凍結培地 Medium + 10% DMSO
凍結方法 Slow freezing
マイコプラズマ (-)
動物種PCR OK
個体識別検査 OK
画像情報
寄託時情報
ロット情報
文献情報 Reference(英) 4件
Reference(日) 0件
利用者成果(英) 296件
利用者成果(日) 0件

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Reference(英)
3489  DuBridge RB, Tang P, Hsia HC, Leong PM, Miller JH, Calos MP.  Analysis of mutation in human cells by using an Epstein-Barr virus shuttle system.  Mol Cell Biol  1987  7(1):379-87  PubMed ID: 3031469
4972  Graham FL, Harrison T, Williams J.  Defective transforming capacity of adenovirus type 5 host-range mutants.  Virology  1978  86(1):10-21  PubMed ID: 664220
2415  Harrison T, Graham F, Williams J  Host-range mutants of adenovirus type 5 defective for growth in HeLa cells.  Virology  1977  77:319-29  PubMed ID: 841862
2414  Graham, F L, Smiley J, Russell, W C, Nairn R  Characteristics of a human cell line transformed by DNA from human adenovirus type 5.  J Gen Virol  1977  36:59-74  PubMed ID: 886304

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Reference(日)

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利用者成果(英)
12798  Johmura Y, Yamanaka T, Omori S, Wang TW, Sugiura Y, Matsumoto M, Suzuki N, Kumamoto S, Yamaguchi K, Hatakeyama S, Takami T, Yamaguchi R, Shimizu E, Ikeda K, Okahashi N, Mikawa R, Suematsu M, Arita M, Sugimoto M, Nakayama KI, Furukawa Y, Imoto S, Nakanishi M.  Senolysis by glutaminolysis inhibition ameliorates various age-associated disorders  Science  2021  371(6526):265-270  PubMed ID: 33446552
13320  Matsumoto N, Sekiya M, Fujimoto Y, Haga S, Sun-Wada GH, Wada Y, Nakanishi-Matsui M.  Functional complementation of V-ATPase a subunit isoforms in osteoclasts.  J Biochem  2021  169(4):459-466  PubMed ID: 33135054
13345  Daifu T, Mikami M, Hiramatsu H, Iwai A, Umeda K, Noura M, Kubota H, Masuda T, Furuichi K, Takasaki S, Noguchi Y, Morita K, Bando T, Hirata M, Kataoka TR, Nakahata T, Kuwahara Y, Iehara T, Hosoi H, Takita J, Sugiyama H, Adachi S, Kamikubo Y.  Suppression of malignant rhabdoid tumors through Chb-M'-mediated RUNX1 inhibition.  Pediatr Blood Cancer  2021    PubMed ID: 33180377
13463  Shota Someya et al  Tryptophan Metabolism Regulates Proliferative Capacity of Human Pluripotent Stem Cells  iScienc  2021  24  PubMed ID: 33615198
20008  Umaba R, Kitanishi T, Mizuseki K.  Monosynaptic connection from the subiculum to medial mammillary nucleus neurons projecting to the anterior thalamus and Gudden's ventral tegmental nucleus.  Neurosci Res  2021    PubMed ID: 33476683
20053  Takafuji S, Mori T, Nishimura N, Yamamoto N, Uemura S, Nozu K, Terui K, Toki T, Ito E, Muramatsu H, Takahashi Y, Matsuo M, Yamamura T, Iijima K.  Usefulness of functional splicing analysis to confirm precise disease pathogenesis in Diamond-Blackfan anemia caused by intronic variants in RPS19.  Pediatr Hematol Oncol  2021  1-16  PubMed ID: 33622161
20060  Nishiike Y, Miyazoe D, Togawa R, Yokoyama K, Nakasone K, Miyata M, Kikuchi Y, Kamei Y, Todo T, Ishikawa-Fujiwara T, Ohno K, Usami T, Nagahama Y, Okubo K.  Estrogen receptor 2b is the major determinant of sex-typical mating behavior and sexual preference in medaka.  Curr Biol  2021    PubMed ID: 33639108
13513  Takahashi Y, Wake H, Sakaguchi M, Yoshii Y, Teshigawara K, Wang D, Nishibori M.  Histidine-Rich Glycoprotein Stimulates Human Neutrophil Phagocytosis and Prolongs Survival through CLEC1A  J Immunol   2021  206(4):737-750  PubMed ID: 33452125
20067  Aizawa N, Fujimori Y, Nakanishi O, Hayashi T, Goi Y, Kobayashi JI, Fujita T.  Efficacy of the combination of KPR-5714, a novel transient receptor potential melastatin 8 (TRPM8) antagonist, and β3-adrenoceptor agonist or anticholinergic agent on bladder dysfunction in rats with bladder overactivity.  Eur J Pharmacol  2021  173995  PubMed ID: 33675781
20068  Nakamura R, Oyama T, Inokuchi M, Ishikawa S, Hirata M, Kawashima H, Ikeda H, Dobashi Y, Ooi A.  Neural EGFL like 2 expressed in myoepithelial cells and suppressed breast cancer cell migration.  Pathol Int  2021    PubMed ID: 33657249
13640  Fujita K, Koide N, Somiya M, Kuroda S, Hinuma S.  A regulatory role of scavenger receptor class B type 1 in endocytosis and lipid droplet formation induced by liposomes containing phosphatidylethanolamine in HEK293T cells  Biochim Biophys Acta Mol Cell Res  2021  1868(1):118859  PubMed ID: 32956759
20083  Hama K, Fujiwara Y, Hayama T, Ozawa T, Nozawa K, Matsuda K, Hashiguchi Y, Yokoyama K.  Very long-chain fatty acids are accumulated in triacylglycerol and nonesterified forms in colorectal cancer tissues.  Sci Rep  2021  11(1):6163  PubMed ID: 33731797
20103  McKee HK, Kajiwara C, Yamaguchi T, Ishii Y, Shimizu N, Ohara A, Tateda K.  Clostridioides difficile toxins enhanced the in vitro production of CXC chemokine ligand 2 and tumor necrosis factor-α via Toll-like receptors in macrophages.  J Med Microbiol  2021  70(4)  PubMed ID: 33830910
13898  Takuma Kitanishi, Ryoko Umaba, Kenji Mizuseki  Robust information routing by dorsal subiculum neurons  Sci Adv  2021  7(11):eabf1913  PubMed ID: 33692111
20114  Ojiro I, Nishio H, Yamazaki-Ito T, Nakano S, Ito S, Toyohara Y, Hiramoto T, Terada Y, Ito K.  Trp-Trp acts as a multi-functional blocker for human bitter taste receptors, hTAS2R14, hTAS2R16, hTAS2R43, and hTAS2R46.  Biosci Biotechnol Biochem  2021    PubMed ID: 33844825
20138  Nagumo Y, Kandori S, Tanuma K, Nitta S, Chihara I, Shiga M, Hoshi A, Negoro H, Kojima T, Mathis BJ, Funakoshi Y, Nishiyama H.  PLD1 promotes tumor invasion by regulation of MMP-13 expression via NF-κB signaling in bladder cancer.  Cancer Lett  2021  511:15-25  PubMed ID: 33945837
20147  Kariya Y, Oyama M, Suzuki T, Kariya Y.  αvβ3 Integrin induces partial EMT independent of TGF-β signaling.  Commun Biol  2021  4(1):490  PubMed ID: 33883697
14182  Somiya M, Kuroda S.  Real-Time Luminescence Assay for Cytoplasmic Cargo Delivery of Extracellular Vesicles  Anal Chem  2021  93(13):5612-5620  PubMed ID: 33759512
20150  Takeshita M, Suzuki K, Nakazawa M, Kamata H, Ishii M, Oyamada Y, Oshima H, Takeuchi T.  Antigen-driven autoantibody production in lungs of interstitial lung disease with autoimmune disease.  J Autoimmun  2021  121:102661  PubMed ID: 34034155
20155  Sahoo PR, Kowada T, Mizukami S.  Long-Term Mg2+ Imaging in Live Cells with a Targetable Fluorescent Probe.  Methods Mol Biol  2021  2274:237-243  PubMed ID: 34050476
20157  Matsui H, Ito J, Matsui N, Uechi T, Onodera O, Kakita A.  Cytosolic dsDNA of mitochondrial origin induces cytotoxicity and neurodegeneration in cellular and zebrafish models of Parkinson's disease.  Nat Commun  2021  12(1):3101  PubMed ID: 34035300
20158  Osakabe K, Wada N, Murakami E, Miyashita N, Osakabe Y.  Genome editing in mammalian cells using the CRISPR type I-D nuclease.  Nucleic Acids Res  2021    PubMed ID: 34076237
20165  Kobayashi JI, Hirasawa H, Fujimori Y, Nakanishi O, Kamada N, Ikeda T, Yamamoto A, Kanbe H.  Identification of N-acyl-N-indanyl-α-phenylglycinamides as selective TRPM8 antagonists designed to mitigate the risk of adverse effects.  Bioorg Med Chem  2021  30:115903  PubMed ID: 33333445
14478  Yamanaka D, Shoda M, Matsubara T, Ishibashi KI, Motoi A, Motoi R, Motoi M, Ohno N, Adachi Y.  Open-Label Study of the Influence of Food Containing the Royal Sun Mushroom, Agaricus brasiliensis KA21 (Agaricomycetes), on β-Glucan-Specific Antibody Production in Healthy Human Volunteers  Int J Med Mushrooms  2021  23(2):13-28  PubMed ID: 33639078
20199  Tomita T, Kato M, Mishima T, Matsunaga Y, Sanjo H, Ito KI, Minagawa K, Matsui T, Oikawa H, Takahashi S, Takao T, Iwai N, Mino T, Takeuchi O, Maru Y, Hiratsuka S.  Extracellular mRNA transported to the nucleus exerts translation-independent function.  Nat Commun  2021  12(1):3655  PubMed ID: 34135341
20200  Kuwabara S, Tanimoto Y, Okutani M, Jie M, Haseda Y, Kinugasa-Katayama Y, Aoshi T.  Microfluidics sorting enables the isolation of an intact cellular pair complex of CD8+ T cells and antigen-presenting cells in a cognate antigen recognition-dependent manner.  PLoS One  2021  16(6):e0252666  PubMed ID: 34125844
20207  Tsuji H, Ohmura K, Jin H, Naito R, Arase N, Kohyama M, Suenaga T, Sakakibara S, Kochi Y, Okada Y, Yamamoto K, Kikutani H, Morinobu A, Mimori T, Arase H.  Anti-dsDNA antibodies recognize DNA presented on HLA class II molecules of systemic lupus erythematosus risk alleles.  Arthritis Rheumatol  2021    PubMed ID: 34164946
20216  Niinae T, Imami K, Sugiyama N, Ishihama Y.  Identification of Endogenous Kinase Substrates by Proximity Labeling Combined with Kinase Perturbation and Phosphorylation Motifs.  Mol Cell Proteomics  2021  100119  PubMed ID: 34186244
14782  Uemura K, Sasaki M, Sanaki T, Toba S, Takahashi Y, Orba Y, Hall WW, Maenaka K, Sawa H, Sato A.  MRC5 cells engineered to express ACE2 serve as a model system for the discovery of antivirals targeting SARS-CoV-2  Sci Rep  2021  11(1):5376  PubMed ID: 33686154
14827  iu Y, Soh WT, Kishikawa JI, Hirose M, Nakayama EE, Li S, Sasai M, Suzuki T, Tada A, Arakawa A, Matsuoka S, Akamatsu K, Matsuda M, Ono C, Torii S, Kishida K, Jin H, Nakai W, Arase N, Nakagawa A, Matsumoto M, Nakazaki Y, Shindo Y, Kohyama M, Tomii K, Ohmura K, Ohshima S, Okamoto T, Yamamoto M, Nakagami H, Matsuura Y, Nakagawa A, Kato T, Okada M, Standley DM, Shioda T, Arase H.  An infectivity-enhancing site on the SARS-CoV-2 spike protein targeted by antibodies  Cell   2021  184(13):3452-3466.e18  PubMed ID: 34139176
20233  Koshizuka T, Kondo H, Kato H, Takahashi K.  Human cytomegalovirus UL42 protein inhibits the degradation of glycoprotein B through inhibition of Nedd4 family ubiquitin E3 ligases.  Microbiol Immunol  2021    PubMed ID: 34260096
20240  Kaku T, Sugiura K, Entani T, Osabe K, Nagai T.  Enhanced brightness of bacterial luciferase by bioluminescence resonance energy transfer.  Sci Rep  2021  11(1):14994  PubMed ID: 34294849
14939  Shuji Hinuma, Kazuyo Fujita, Shun’ichi Kuroda  Binding of Nanoparticles Harboring Recombinant Large Surface Protein of Hepatitis B Virus to Scavenger Receptor Class B Type 1  Viruses  2021  13:1334 
20244  Yoshioka K, Obara K, Oikawa S, Uemura K, Yamaguchi A, Fujisawa K, Hanazawa H, Fujiwara M, Endoh T, Suzuki T, Regadera MD, Ito D, Ou G, Xu K, Tanaka Y.  Docosahexaenoic acid inhibits U46619- and prostaglandin F2α-induced pig coronary and basilar artery contractions by inhibiting prostanoid TP receptors.  Eur J Pharmacol  2021  174371  PubMed ID: 34329614
15168  Hangai S, Kawamura T, Kimura Y, Chang CY, Hibino S, Yamamoto D, Nakai Y, Tateishi R, Oshima M, Oshima H, Kodama T, Moriya K, Koike K, Yanai H, Taniguchi T.  Orchestration of myeloid-derived suppressor cells in the tumor microenvironment by ubiquitous cellular protein TCTP released by tumor cells  Nat Immunol  2021  22(8):947-957  PubMed ID: 34239121
20282  Nakanishi E, Uemura N, Akiyama H, Kinoshita M, Masanori S, Taruno Y, Yamakado H, Matsuzawa SI, Takeda S, Hirabayashi Y, Takahashi R.  Impact of Gba2 on neuronopathic Gaucher's disease and α-synuclein accumulation in medaka (Oryzias latipes).  Mol Brain  2021  14(1):80  PubMed ID: 33971917
20283  Sakoguchi A, Saito F, Hirayasu K, Shida K, Matsuoka S, Itagaki S, Nakai W, Kohyama M, Suenaga T, Iwanaga S, Horii T, Arase H.  Plasmodium falciparum RIFIN is a novel ligand for inhibitory immune receptor LILRB2.  Biochem Biophys Res Commun  2021  548:167-173  PubMed ID: 33647792
20298  Nagano C, Takaoka Y, Kamei K, Hamada R, Ichikawa D, Tanaka K, Aoto Y, Ishiko S, Rossanti R, Sakakibara N, Okada E, Horinouchi T, Yamamura T, Tsuji Y, Noguchi Y, Ishimori S, Nagase H, Ninchoji T, Iijima K, Nozu K.  Genotype-Phenotype Correlation in WT1 Exon 8 to 9 Missense Variants.  Kidney Int Rep  2021  6(8):2114-2121  PubMed ID: 34386660
20322  Fujisawa S, Qiu H, Nozaki S, Chiba S, Katoh Y, Nakayama K.  ARL3 and ARL13B GTPases participate in distinct steps of INPP5E targeting to the ciliary membrane.  Biol Open  2021    PubMed ID: 34447983
15284  Yoshiko Iizuka, Kinuko Inomata, Risako Nohara, Akimitsu Miyawaki and Yoshifumi Watanabe  Activation of intracellular antioxidant master gene Nrf2 by the extracts of Garcinia subelliptica, Ocimum gratissimum L., and Plectranthus ornatus  International Journal of Herbal Medicine  2021  9(3):54-60 
11854  Yamamoto M, Terada Y, Motoyama T, Saito T, Ito K.  Sweet proteins lysozyme and thaumatin are protein-type agonists for the calcium-sensing receptor.  Biochem. Biophys. Res. Commun.  2020  521(1):227-231  PubMed ID: 31635806
6889  Iuchi K, Oya K, Hosoya K, Sasaki K, Sakurada Y, Nakano T, Hisatomi H.  Different morphologies of human embryonic kidney 293T cells in various types of culture dishes.  Cytotechnology  2020  72(1):131-140  PubMed ID: 31865498
9863  Naomi Matsumoto, Reina Matsukawa, Shohei Takahashi, Koshi Kudo, Ge-Hong Sun-Wada, Yoh Wada, Mayumi Nakanishi-Matsui  V-ATPase a3 Isoform Mutations Identified in Osteopetrosis Patients Abolish Its Expression and Disrupt Osteoclast Function  Exp Cell Res  2020  389(2):111901  PubMed ID: 32045577
9912  Hiroshi Suzuki, Yuichi Ozaki, Shigeho Ijiri, Koichiro Gen, Yukinori Kazeto  17β-Hydroxysteroid Dehydrogenase Type 12a Responsible for Testicular 11-ketotestosterone Synthesis in the Japanese Eel, Anguilla Japonica  J Steroid Biochem Mol Biol  2020  198:105550  PubMed ID: 31778803
10370  Yusuke Higuchi, Jun-Ichirou Yasunaga, Yu Mitagami, Hirotake Tsukamoto, Kazutaka Nakashima, Koichi Ohshima, Masao Matsuoka  HTLV-1 Induces T Cell Malignancy and Inflammation by Viral Antisense Factor-Mediated Modulation of the Cytokine Signaling  Proc Natl Acad Sci U S A  2020  117(24):13740-13749  PubMed ID: 32471947
11909  Sakaue T, Hamaguchi M, Aono J, Nakashiro KI, Shikata F, Kawakami N, Oshima Y, Kurata M, Nanba D, Masumoto J, Yamaguchi O, Higashiyama S, Izutani H.  Valve Interstitial Cell-Specific Cyclooxygenase-1 Associated With Calcification of Aortic Valves.  Ann. Thorac. Surg  2020  110(1):40-49  PubMed ID: 31760051
11927  Yang J, Isaji T, Zhang G, Qi F, Duan C, Fukuda T, Gu J.  EpCAM associates with integrin and regulates cell adhesion in cancer cells.  Biochem. Biophys. Res. Commun.  2020    PubMed ID: 31806375
11944  Qi F, Isaji T, Duan C, Yang J, Wang Y, Fukuda T, Gu J.  ST3GAL3, ST3GAL4, and ST3GAL6 differ in their regulation of biological functions via the specificities for the α2,3-sialylation of target proteins.  FASEB J.  2020    PubMed ID: 31914669
11952  Kimura R, Yoshimaru T, Matsushita Y, Matsuo T, Ono M, Park JH, Sasa M, Miyoshi Y, Nakamura Y, Katagiri T.  The GALNT6‑LGALS3BP axis promotes breast cancer cell growth.  Int. J. Oncol.  2020    PubMed ID: 31894262
11958  Hou S, Hang Q, Isaji T, Fukuda T, Gu J.  Identification of the minimal N-glycosylation on integrin α5β1 required for its inhibitory effect on EGFR signaling and cell proliferation.  Biochem. Biophys. Res. Commun.  2020    PubMed ID: 31858971
11990  Duan C, Fukuda T, Isaji T, Qi F, Yang J, Wang Y, Takahashi S, Gu J.  Deficiency of core fucosylation activates cellular signaling dependent on FLT3 expression in a Ba/F3 cell system.  FASEB J.  2020    PubMed ID: 31908039
12005  Kabayama H, Takeuchi M, Tokushige N, Muramatsu SI, Kabayama M, Fukuda M, Yamada Y, Mikoshiba K.  An ultra-stable cytoplasmic antibody engineered for in vivo applications.  Nat Commun  2020    PubMed ID: 31953402
12015  Yamamoto H, Kon T, Omori Y, Furukawa T.  Functional and Evolutionary Diversification of Otx2 and Crx in Vertebrate Retinal Photoreceptor and Bipolar Cell Development.  Cell Rep  2020    PubMed ID: 31968244
12027  Momoi Y, Nishikimi A, Du G, Kataoka T, Katagiri K.  Phosphatidic acid regulates subcellular distribution of RA-GEFs critical for chemokine-dependent migration.  Biochem. Biophys. Res. Commun.  2020    PubMed ID: 31996307
12028  Iuchi K, Tasaki Y, Shirai S, Hisatomi H.  Upregulation of nuclear factor (erythroid-derived 2)-like 2 protein level in the human colorectal adenocarcinoma cell line DLD-1 by a heterocyclic organobismuth(III) compound: Effect of organobismuth(III) compound on NRF2 signaling.  Biomed. Pharmacother.  2020    PubMed ID: 32004978
12086  Honda A, Chigwechokha PK, Takase R, Hayasaka O, Fujimura K, Kotani T, Komatsu M, Shiozaki K.  Novel Nile tilapia Neu1 sialidases: Molecular cloning and biochemical characterization of the sialidases Neu1a and Neu1b.  Gene  2020    PubMed ID: 32184168
12096  Funakoshi-Tago M, Yu S, Kushida A, Takeuchi K, Tamura H.  Kampo medicines, Rokumigan, Hachimijiogan, and Goshajinkigan, significantly inhibit glucagon-induced CREB activation.  Heliyon  2020    PubMed ID: 32215330
12129  Mutai H, Wasano K, Momozawa Y, Kamatani Y, Miya F, Masuda S, Morimoto N, Nara K, Takahashi S, Tsunoda T, Homma K, Kubo M, Matsunaga T.  Variants encoding a restricted carboxy-terminal domain of SLC12A2 cause hereditary hearing loss in humans.  PLoS Genet.  2020    PubMed ID: 32294086
12364  Liu X, Tajima N, Taniguchi M, Kato N.  The enantiomer pair of 24S- and 24R-hydroxycholesterol differentially alter activity of large-conductance Ca 2+ -dependent K + (slo1 BK) channel  Chirality  2020  32(2):223-230  PubMed ID: 31756018
12487  Yafei Liu et al  An infectivity-enhancing site on the SARS-CoV-2 spike protein is targeted by COVID-19 patient antibodies  bioRxiv  2020  December 18 
13019  Matsuzaki M, Mandai M, Yamanari M, Totani K, Nishida M, Sugita S, Maeda T, Koide N, Takagi S, Hirami Y, Miyamoto N, Sugiyama S, Takahashi M, Kurimoto Y.  Polarization-sensitive optical coherence tomography for estimating relative melanin content of autologous induced stem-cell derived retinal pigment epithelium.  Sci Rep  2020    PubMed ID: 32376945
13020  Koshizuka T, Inoue N.  Activation of c-Jun by human cytomegalovirus UL42 through JNK activation.  PLoS One  2020    PubMed ID: 32369499
13024  Kanoh H, Nitta T, Go S, Inamori KI, Veillon L, Nihei W, Fujii M, Kabayama K, Shimoyama A, Fukase K, Ohto U, Shimizu T, Watanabe T, Shindo H, Aoki S, Sato K, Nagasaki M, Yatomi Y, Komura N, Ando H, Ishida H, Kiso M, Natori Y, Yoshimura Y, Zonca A, Cattaneo A, Letizia M, Ciampa M, Mauri L, Prinetti A, Sonnino S, Suzuki A, Inokuchi JI.  Homeostatic and pathogenic roles of GM3 ganglioside molecular species in TLR4 signaling in obesity.  EMBO J  2020    PubMed ID: 32378734
13028  Kido K, Yamanaka S, Nakano S, Motani K, Shinohara S, Nozawa A, Kosako H, Ito S, Sawasaki T.  AirID, a novel proximity biotinylation enzyme, for analysis of protein-protein interactions.  Elife  2020    PubMed ID: 32391793
13034  Bajkowska K, Sumardika IW, Tomonobu N, Chen Y, Yamamoto KI, Kinoshita R, Murata H, Gede Yoni Komalasari NL, Jiang F, Yamauchi A, Winarsa Ruma IM, Kasano-Camones CI, Inoue Y, Sakaguchi M.  Neuroplastinβ-mediated upregulation of solute carrier family 22 member 18 antisense (SLC22A18AS) plays a crucial role in the epithelial-mesenchymal transition, leading to lung cancer cells' enhanced motility.  Biochem Biophys Rep  2020    PubMed ID: 32490214
13044  Park M, Miyoshi C, Fujiyama T, Kakizaki M, Ikkyu A, Honda T, Choi J, Asano F, Mizuno S, Takahashi S, Yanagisawa M, Funato H.  Loss of the conserved PKA sites of SIK1 and SIK2 increases sleep need.  Sci Rep  2020    PubMed ID: 32457359
13074  Horinouchi T, Yamamura T, Minamikawa S, Nagano C, Sakakibara N, Nakanishi K, Shima Y, Morisada N, Ishiko S, Aoto Y, Nagase H, Takeda H, Rossanti R, Ishimori S, Kaito H, Matsuo M, Iijima K, Nozu K.  Pathogenic evaluation of synonymous COL4A5 variants in X-linked Alport syndrome using a minigene assay.  Mol Genet Genomic Med  2020    PubMed ID: 32543079
13080  Ito F, Yanatori I, Maeda Y, Nimura K, Ito S, Hirayama T, Nagasawa H, Kohyama N, Okazaki Y, Akatsuka S, Toyokuni S.  Asbestos conceives Fe(II)-dependent mutagenic stromal milieu through ceaseless macrophage ferroptosis and β-catenin induction in mesothelium.  Redox Biol  2020    PubMed ID: 32863225
13164  Yamashita J, Takeuchi A, Hosono K, Fleming T, Nagahama Y, Okubo K.  Male-predominant galanin mediates androgen-dependent aggressive chases in medaka.  Elife  2020    PubMed ID: 32783809
13182  Ishibashi R, Abe K, Ido N, Kitano S, Miyachi H, Toyoshima F.  Genome editing with the donor plasmid equipped with synthetic crRNA-target sequence.  Sci Rep  2020    PubMed ID: 32839482
13186  Huetter J, Gritzan U, Gutcher I, Doecke WD, Luetke-Eversloh MV, Golfier S, Roider HG, Frisk AL, Hunter J, Pow A, Drake A, Levine Z, Levy O, Azulay M, Barbiro I, Cojocaru G, Vaknin I, Kreft B, Roese L.  Characterization of BAY 1905254, an Immune Checkpoint Inhibitor Targeting the Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2).  Cancer Immunol Res  2020    PubMed ID: 32312711
13199  Kakizawa S, Kishimoto Y, Yamamoto S, Onga K, Yasuda K, Miyamoto Y, Watanabe M, Sakai R, Mori N.  Functional maintenance of calcium store by ShcB adaptor protein in cerebellar Purkinje cells.  Sci Rep  2020    PubMed ID: 32879382
13200  Ago Y, Otsuka H, Sasai H, Abdelkreem E, Nakama M, Aoyama Y, Matsumoto H, Fujiki R, Ohara O, Akiyama K, Fukui K, Watanabe Y, Nakajima Y, Ohnishi H, Ito T, Fukao T.  Japanese patients with mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase deficiency: In vitro functional analysis of five novel HMGCS2 mutations.  Exp Ther Med  2020    PubMed ID: 32952630
13204  Kinoshita N, Huang AJY, McHugh TJ, Miyawaki A, Shimogori T.  Diffusible GRAPHIC to visualize morphology of cells after specific cell-cell contact.  Sci Rep  2020    PubMed ID: 32879377
13212  Kitao T, Taguchi K, Seto S, Arasaki K, Ando H, Nagai H, Kubori T.  Legionella Manipulates Non-canonical SNARE Pairing Using a Bacterial Deubiquitinase.  Cell Rep  2020    PubMed ID: 32905772
13276  Arai Y, Kawashita N, Elgendy EM, Ibrahim MS, Daidoji T, Ono T, Takagi T, Nakaya T, Matsumoto K, Watanabe Y.  PA Mutations Inherited during Viral Evolution Act Cooperatively To Increase Replication of Contemporary H5N1 Influenza Virus with an Expanded Host Range.  J Virol  2020    PubMed ID: 33028722
13293  Okamura M, Shizu R, Abe T, Kodama S, Hosaka T, Sasaki T, Yoshinari K.  PXR Functionally Interacts with NF-κB and AP-1 to Downregulate the Inflammation-Induced Expression of Chemokine CXCL2 in Mice.  Cells  2020    PubMed ID: 33076328
13321  Kato M, Onoyama I, Kawakami M, Yoshida S, Kawamura K, Kodama K, Hori E, Cui L, Matsumura Y, Yagi H, Asanoma K, Yahata H, Itakura A, Takeda S, Kato K.  Downregulation of 5-hydroxymethylcytosine is associated with the progression of cervical intraepithelial neoplasia.  PLoS One  2020    PubMed ID: 33141854
13327  Yamazaki T, Takahashi C, Taniguchi Y, Narukawa M, Misaka T, Ano Y.  Bitter taste receptor activation by hop-derived bitter components induces gastrointestinal hormone production in enteroendocrine cells.  Biochem Biophys Res Commun  2020    PubMed ID: 33160623
13330  Osakabe K, Wada N, Miyaji T, Murakami E, Marui K, Ueta R, Hashimoto R, Abe-Hara C, Kong B, Yano K, Osakabe Y.  Genome editing in plants using CRISPR type I-D nuclease.  Commun Biol  2020  3(1):648  PubMed ID: 33159140
13490  Shoji S, Hanada K, Takahashi M, Watanabe K, Yonemochi M, Tomabechi Y, Shirouzu M.  The NF-κB regulator IκBβ exhibits different molecular interactivity and phosphorylation status from IκBα in an IKK2-catalysed reaction  FEBS Lett  2020  594(10):1532-1549  PubMed ID: 32017069
13554  Tohama T, Sakari M, Tsukahara T.  Development of a Single Construct System for Site-Directed RNA Editing Using MS2-ADAR  Int J Mol Sci  2020  ;21(14):4943  PubMed ID: 32668759
13567  Harada M, Nghia VT, Nakao A, Tanigaki R, Fukuoka N, Nishida A, Kataoka T.  Eomesodermin promotes interaction of RelA and NFATc2 with the Ifng promoter and multiple conserved noncoding sequences across the Ifng locus in mouse lymphoma BW5147 cells  Immunol Lett  2020  225:33-43  PubMed ID: 32554052
13570  Suzuki T, Morimoto N, Akaike A, Osakada F.  Multiplex Neural Circuit Tracing With G-Deleted Rabies Viral Vectors  Front Neural Circuits  2020  13:77  PubMed ID: 31998081
13575  Suzuki F, Okuno M, Tanaka T, Sanuki R.  Overexpression of neural miRNAs miR-9/9* and miR-124 suppresses differentiation to Müller glia and promotes differentiation to neurons in mouse retina in vivo  Genes Cells  2020  25(11):741-752  PubMed ID: 32979863
13577  Shimada K, Kobayashi N, Oka N, Takahashi M, Kondo K.  Cooperative activation of the human herpesvirus 6B U79/80 early gene promoter by immediate-early proteins IE1B and IE2B  Microbiol Immunol  2020  64(11):747-761  PubMed ID: 32910457
13599  Murakami S, Mochimaru Y, Musha S, Kojima R, Deai M, Mogi C, Sato K, Okajima F, Tomura H.  Species-Dependent Enhancement of Ovarian Cancer G Protein-Coupled Receptor 1 Activation by Ogerin  Zoolog Sci  2020  37(2):103-108  PubMed ID: 32282140
13606  Wardhani BW, Puteri MU, Watanabe Y, Louisa M, Setiabudy R, Kato M.  TGF-β-Induced TMEPAI Attenuates the Response of Triple-Negative Breast Cancer Cells to Doxorubicin and Paclitaxel  J Exp Pharmacol  2020  12:17-26  PubMed ID: 32158279
13629  Yamamoto M, Terada Y, Motoyama T, Shibata M, Saito T, Ito K.  N-terminal [Glu] 3 moiety of γ-glutamyl peptides contributes largely to the activation of human calcium-sensing receptor, a kokumi receptor  Biosci Biotechnol Biochem  2020  84(7):1497-1500  PubMed ID: 32202205
13772  Sawada Y, Kikugawa T, Iio H, Sakakibara I, Yoshida S, Ikedo A, Yanagihara Y, Saeki N, Győrffy B, Kishida T, Okubo Y, Nakamura Y, Miyagi Y, Saika T, Imai Y.  GPRC5A facilitates cell proliferation through cell cycle regulation and correlates with bone metastasis in prostate cancer  Int J Cancer  2020  146(5):1369-1382  PubMed ID: 31276604
13913  Rai D, Akagi T, Shimohata A, Ishii T, Gangi M, Maruyama T, Wada-Kiyama Y, Ogiwara I, Kaneda M.  Involvement of the C-terminal domain in cell surface localization and G-protein coupling of mGluR6  J Neurochem  2020  Oct 17  PubMed ID: 33067823
14525  Ishida H, Murakami S, Kamiki H, Matsugo H, Takenaka-Uema A, Horimoto T.  Establishment of a Reverse Genetics System for Influenza D Virus  J Virol  2020  94(10):e01767-19  PubMed ID: 32102883
14805  Yokomizo-Nakano T, Kubota S, Bai J, Hamashima A, Morii M, Sun Y, Katagiri S, Iimori M, Kanai A, Tanaka D, Oshima M, Harada Y, Ohyashiki K, Iwama A, Harada H, Osato M, Sashida G.  Overexpression of RUNX3 Represses RUNX1 to Drive Transformation of Myelodysplastic Syndrome  Cancer Res  2020  80(12):2523-2536  PubMed ID: 32341038
14840  Ueo A, Kubota M, Shirogane Y, Ohno S, Hashiguchi T, Yanagi Y.  Lysosome-Associated Membrane Proteins Support the Furin-Mediated Processing of the Mumps Virus Fusion Protein  J Virol   2020  94(12):e00050-20  PubMed ID: 32295904
14855  Effective RNA Knockdown Using CRISPR-Cas13a and Molecular Targeting of the EML4-ALK Transcript in H3122 Lung Cancer Cells  Effective RNA Knockdown Using CRISPR-Cas13a and Molecular Targeting of the EML4-ALK Transcript in H3122 Lung Cancer Cells  Int J Mol Sci   2020  21(23):8904  PubMed ID: 33255340
14862  Mizutani T, Ohba Y, Mizuta S, Yasuda J, Urata S.  An Antiviral Drug Screening Platform with a FRET Biosensor for Measurement of Arenavirus Z Assembly  Cell Struct Funct   2020  45(2):155-163  PubMed ID: 33191384
14868  Toda K, Tsukayama I, Nagasaki Y, Konoike Y, Tamenobu A, Ganeko N, Ito H, Kawakami Y, Takahashi Y, Miki Y, Yamamoto K, Murakami M, Suzuki-Yamamoto T.  Red-kerneled rice proanthocyanidin inhibits arachidonate 5-lipoxygenase and decreases psoriasis-like skin inflammation  Arch Biochem Biophys  2020  689:108307  PubMed ID: 32112739
20272  Ma Y, Yoshida T, Matoba K, Kida K, Shintani R, Piao Y, Jin J, Nishino T, Hanayama R.  Identification of small compounds regulating the secretion of extracellular vesicles via a TIM4-affinity ELISA.  Sci Rep  2020  11(1):13471  PubMed ID: 34188113
11244  Zhang G, Isaji T, Xu Z, Lu X, Fukuda T, Gu J.  N-acetylglucosaminyltransferase-I as a novel regulator of epithelial-mesenchymal transition.  FASEB J.  2019    PubMed ID: 30307765
11273  Mizuno M, Miki R, Moriyama Y, Ushida T, Imai K, Niimi K, Nakano T, Tsuda H, Sumigama S, Yamamoto E, Senga T, Iwase A, Kikkawa F, Kotani T.  The role of E2F8 in the human placenta.  Mol Med Rep  2019    PubMed ID: 30387815
11319  Nitta T, Kanoh H, Inamori KI, Suzuki A, Takahashi T, Inokuchi JI.  Globo-series glycosphingolipids enhance Toll-like receptor 4-mediated inflammation and play a pathophysiological role in diabetic nephropathy.  Glycobiology  2019    PubMed ID: 30476082
11315  Arai Y, Ibrahim MS, Elgendy EM, Daidoji T, Ono T, Suzuki Y, Nakaya T, Matsumoto K, Watanabe Y.  Genetic Compatibility of Reassortants between Avian H5N1 and H9N2 Influenza Viruses with Higher Pathogenicity in Mammals.  J. Virol.  2019    PubMed ID: 30463961
11327  Ishikawa K, Hara T, Kato K, Shimomura T, Omori K.  Involvement of natriuretic peptide system in C2C12 myocytes.  Mol. Cell. Biochem.  2019  56(1-2):15-27  PubMed ID: 30519782
11355  Xu Z, Isaji T, Fukuda T, Wang Y, Gu J.  O-GlcNAcylation regulates integrin-mediated cell adhesion and migration via formation of focal adhesion complexes.  J. Biol. Chem.  2019    PubMed ID: 30587575
11368  Suzuki N, Hirano K, Ogino H, Ochi H.  Arid3a regulates nephric tubule regeneration via evolutionarily conserved regeneration signal-response enhancers.  Elife  2019    PubMed ID: 30616715
11404  Kataoka K, Miyoshi H, Sakata S, Dobashi A, Couronné L, Kogure Y, Sato Y, Nishida K, Gion Y, Shiraishi Y, Tanaka H, Chiba K, Watatani Y, Kakiuchi N, Shiozawa Y, Yoshizato T, Yoshida K, Makishima H, Sanada M, Onozawa M, Teshima T, Yoshiki Y, Ishida T, Suzuki K, Shimada K, Tomita A, Kato M, Ota Y, Izutsu K, Demachi-Okamura A, Akatsuka Y, Miyano S, Yoshino T, Gaulard P, Hermine O, Takeuchi K, Ohshima K, Ogawa S.  Frequent structural variations involving programmed death ligands in Epstein-Barr virus-associated lymphomas.  Leukemia  2019    PubMed ID: 30683910
11416  Matsumoto N, Nakanishi-Matsui M.  Proton pumping V-ATPase inhibitor bafilomycin A1 affects Rab7 lysosomal localization and abolishes anterograde trafficking of osteoclast secretory lysosomes.  Biochem. Biophys. Res. Commun.  2019    PubMed ID: 30717974
11418  Shimizu Y, Kohyama M, Yorifuji H, Jin H, Arase N, Suenaga T, Arase H.  FcγRIIIA-mediated activation of NK cells by IgG heavy chain complexed with MHC class II molecules.  Int. Immunol.  2019    PubMed ID: 30721990
11430  Ishibashi D, Homma T, Nakagaki T, Fuse T, Sano K, Satoh K, Mori T, Atarashi R, Nishida N.  Type I interferon protects neurons from prions in in vivo models.  Brain  2019    PubMed ID: 30753318
11475  Yorifuji H, Arase N, Kohyama M, Hirano T, Suenaga T, Kumanogoh A, Arase H.  Transport of cellular misfolded proteins to the cell surface by HLA-B27 free heavy chain.  Biochem. Biophys. Res. Commun.  2019    PubMed ID: 30850159
11465  Sarkar B, Nishikata I, Nakahata S, Ichikawa T, Shiraga T, Saha HR, Fujii M, Tanaka Y, Shimoda K, Morishita K.  Degradation of p47 by autophagy contributes to CADM1 overexpression in ATLL cells through the activation of NF-κB.  Sci Rep  2019    PubMed ID: 30837480
11490  Chen Y, Sumardika IW, Tomonobu N, Winarsa Ruma IM, Kinoshita R, Kondo E, Inoue Y, Sato H, Yamauchi A, Murata H, Yamamoto KI, Tomida S, Shien K, Yamamoto H, Soh J, Liu M, Futami J, Sasai K, Katayama H, Kubo M, Putranto EW, Hibino T, Sun B, Nishibori M, Toyooka S, Sakaguchi M.  Melanoma cell adhesion molecule is the driving force behind the dissemination of melanoma upon S100A8/A9 binding in the original skin lesion.  Cancer Lett.  2019    PubMed ID: 30904617
5345  Yamaguchi S, Tanimoto A, Iwasa S, Otsuguro KI.  TRPM4 and TRPM5 Channels Share Crucial Amino Acid Residues for Ca2+ Sensitivity but Not Significance of PI(4,5)P2.  Int J Mol Sci  2019  20(8):2012  PubMed ID: 31022885
6833  Yokoyama T, Machida K, Iwasaki W, Shigeta T, Nishimoto M, Takahashi M, Sakamoto A, Yonemochi M, Harada Y, Shigematsu H, Shirouzu M, Tadakuma H, Imataka H, Ito T.  HCV IRES Captures an Actively Translating 80S Ribosome.  Mol Cell  2019  74(6):1205-1214  PubMed ID: 31080011
11500  Mizuta H, Kuga K, Suzuki T, Niwa Y, Dohmae N, Simizu S.  C‑mannosylation of R‑spondin2 activates Wnt/β‑catenin signaling and migration activity in human tumor cells.  Int. J. Oncol.  2019    PubMed ID: 30942431
11520  Liu YY, Tanikawa C, Ueda K, Matsuda K.  INKA2, a novel p53 target that interacts with the serine/threonine kinase PAK4.  Int. J. Oncol.  2019    PubMed ID: 31081062
11554  Matsubara H, Tanaka R, Tateishi T, Yoshida H, Yamaguchi M, Kataoka T.  The human Bcl-2 family member Bcl-rambo and voltage-dependent anion channels manifest a genetic interaction in Drosophila and cooperatively promote the activation of effector caspases in human cultured cells.  Exp. Cell Res.  2019    PubMed ID: 31102594
11555  Chen Y, Sumardika IW, Tomonobu N, Kinoshita R, Inoue Y, Iioka H, Mitsui Y, Saito K, Ruma IMW, Sato H, Yamauchi A, Murata H, Yamamoto KI, Tomida S, Shien K, Yamamoto H, Soh J, Futami J, Kubo M, Putranto EW, Murakami T, Liu M, Hibino T, Nishibori M, Kondo E, Toyooka S, Sakaguchi M.  Critical role of the MCAM-ETV4 axis triggered by extracellular S100A8/A9 in breast cancer aggressiveness.  Neoplasia  2019    PubMed ID: 31100639
11580  Tanaka J, Mabuchi Y, Hata K, Yasuhara R, Takamatsu K, Kujiraoka S, Yukimori A, Takakura I, Sumimoto H, Fukada T, Azuma M, Akiyama H, Nishimura R, Shimane T, Mishima K.  Sox9 regulates the luminal stem/progenitor cell properties of salivary glands.  Exp. Cell Res.  2019    PubMed ID: 31153924
11621  Arai Y, Kawashita N, Ibrahim MS, Elgendy EM, Daidoji T, Ono T, Takagi T, Nakaya T, Matsumoto K, Watanabe Y.  PB2 mutations arising during H9N2 influenza evolution in the Middle East confer enhanced replication and growth in mammals.  PLoS Pathog.  2019    PubMed ID: 31265471
11624  Furuse Y, Chaimongkol N, Okamoto M, Oshitani H.  Evolutionary and Functional Diversity of the 5' Untranslated Region of Enterovirus D68: Increased Activity of the Internal Ribosome Entry Site of Viral Strains during the 2010s.  Viruses  2019    PubMed ID: 31288421
11643  Ishii J, Suzuki A, Kimura T, Tateyama M, Tanaka T, Yazawa T, Arimasu Y, Chen IS, Aoyama K, Kubo Y, Saitoh S, Mizuno H, Kamma H.  Congenital goitrous hypothyroidism is caused by dysfunction of the iodide transporter SLC26A7.  Commun Biol  2019    PubMed ID: 31372509
11647  Wong JH, Shigemizu D, Yoshii Y, Akiyama S, Tanaka A, Nakagawa H, Narumiya S, Fujimoto A.  Identification of intermediate-sized deletions and inference of their impact on gene expression in a human population.  Genome Med  2019    PubMed ID: 31340865
11716  Makino Y, Jensen NH, Yokota N, Rossner MJ, Akiyama H, Shirahige K, Okada Y.  Single cell RNA-sequencing identified Dec2 as a suppressive factor for spermatogonial differentiation by inhibiting Sohlh1 expression.  Sci Rep  2019    PubMed ID: 30988352
11720  Yamanashi T, Maki M, Kojima K, Shibukawa A, Tsukamoto T, Chowdhury S, Yamanaka A, Takagi S, Sudo Y.  Quantitation of the neural silencing activity of anion channelrhodopsins in Caenorhabditis elegans and their applicability for long-term illumination.  Sci Rep  2019    PubMed ID: 31133660
11766  Su Y, Nichuguti N, Kuroki-Kami A, Fujiwara H.  Sequence-specific retrotransposition of 28S rDNA-specific LINE R2Ol in human cells.  RNA  2019    PubMed ID: 31434792
11845  Kamiki H, Matsugo H, Ishida H, Kobayashi-Kitamura T, Sekine W, Takenaka-Uema A, Murakami S, Horimoto T.  Adaptation of H3N2 canine influenza virus to feline cell culture.  PLoS ONE  2019    PubMed ID: 31600274
11855  Morita A, Aoshima K, Gulay KCM, Onishi S, Shibata Y, Yasui H, Kobayashi A, Kimura T.  High drug efflux pump capacity and low DNA damage response induce doxorubicin resistance in canine hemangiosarcoma cell lines.  Res. Vet. Sci.  2019    PubMed ID: 31648115
6886  Musha S, Nagayama S, Murakami S, Kojima R, Deai M, Sato K, Okajima F, Ueharu H, Tomura H.  Protons Differentially Activate TDAG8 Homologs from Various Species.  Zoolog Sci  2019  36(2):105-111  PubMed ID: 31120644
6931  Nakanishi M, Hino M, Yoshimura M, Amakura Y, Nomoto H.  Identification of sinensetin and nobiletin as major antitrypanosomal factors in a citrus cultivar.  Exp Parasitol  2019  200:24-29  PubMed ID: 30898543
9468  Kazuyo Fujita, Masaharu Somiya, Shun'ichi Kuroda, Shuji Hinuma  Induction of Lipid Droplets in Non-Macrophage Cells as Well as Macrophages by Liposomes and Exosomes  Biochem Biophys Res Commun  2019  510(1):184-190  PubMed ID: 30678809
11700  Uchibori R, Teruya T, Ido H, Ohmine K, Sehara Y, Urabe M, Mizukami H, Mineno J, Ozawa K.  Functional Analysis of an Inducible Promoter Driven by Activation Signals from a Chimeric Antigen Receptor  Mol Ther Oncolytics  2019  2:16-25  PubMed ID: 30662937
12285  Arisa Mitani, Takeshi Kobayashi, Yasuhito Hayashi, Natsuki Matsushita, Sachi Matsushita, Saori Nakao, Naoko Takahira, Atsushi Shiraishi, Yuichi Ohashi   Characterization of doxycycline-dependent inducible Simian Virus 40 large T antigen immortalized human conjunctival epithelial cell line  PLoS One  2019  14(9):e0222454  PubMed ID: 31509592
12299  Nobuyoshi Tajima, Liu Xiaoyan, Makoto Taniguchi, Nobuo Kato  24S-hydroxycholesterol alters activity of large-conductance Ca 2+-dependent K + (slo1 BK) channel through intercalation into plasma membrane  Biochim Biophys Acta Mol Cell Biol Lipids  2019  1864(10):1525-1535  PubMed ID: 31136842
12354  Shimizu K, Yamasaki S, Sakurai M, Yumoto N, Ikeda M, Mishima-Tsumagari C, Kukimoto-Niino M, Watanabe T, Kawamura M, Shirouzu M, Fujii SI.  Granzyme A Stimulates pDCs to Promote Adaptive Immunity via Induction of Type I IFN  Front Immunol  2019  10:1450  PubMed ID: 31293597
12362  Takahashi Y, Takahashi H, Stern PL, Kirita T, Tsuboi A.  Expression of Oncofetal Antigen 5T4 in Murine Taste Papillae  Front Cell Neurosci  2019  13:343  PubMed ID: 31417363
12363  Ichikawa T, Nakahata S, Fujii M, Iha H, Shimoda K, Morishita K.  The regulation of NDRG2 expression during ATLL development after HTLV-1 infection  Biochim Biophys Acta Mol Basis Dis  2019  1865(10):2633-2646  PubMed ID: 31295529
12365  Okamura M, Shizu R, Hosaka T, Sasaki T, Yoshinari K.  Possible involvement of the competition for the transcriptional coactivator glucocorticoid receptor-interacting protein 1 in the inflammatory signal-dependent suppression of PXR-mediated CYP3A induction in vitro  Drug Metab Pharmacokinet  2019  34(4):272-279  PubMed ID: 31280915
12367  Mitsui Y, Tomonobu N, Watanabe M, Kinoshita R, Sumardika IW, Youyi C, Murata H, Yamamoto KI, Sadahira T, Rodrigo AGH, Takamatsu H, Araki K, Yamauchi A, Yamamura M, Fujiwara H, Inoue Y, Futami J, Saito K, Iioka H, Kondo E, Nishibori M, Toyooka S, Yamamoto Y, Nasu Y, Sakaguchi M.  Upregulation of Mobility in Pancreatic Cancer Cells by Secreted S100A11 Through Activation of Surrounding Fibroblasts  Oncol Res  2019  27(8):945-956.  PubMed ID: 31046874
12437  Hara N, Osago H, Hiyoshi M, Kobayashi-Miura M, Tsuchiya M.  Quantitative analysis of the effects of nicotinamide phosphoribosyltransferase induction on the rates of NAD+ synthesis and breakdown in mammalian cells using stable isotope-labeling combined with mass spectrometry  PLoS One  2019  14(3):e0214000  PubMed ID: 30875389
12496  Liu Y, Wang Y, Wang F, Pan J, Xu J, Li J, Zhou C, Ding G, Wu Y, Liu X, Sheng J, Huang H.  Mechanism underlying the retarded nuclear translocation of androgen receptor splice variants  Sci China Life Sci  2019  62(2):257-267  PubMed ID: 30267260
12588  Yoh T, Hatano E, Kasai Y, Fuji H, Nishi K, Toriguchi K, Sueoka H, Ohno M, Seo S, Iwaisako K, Taura K, Yamaguchi R, Kurokawa M, Fujimoto J, Kimura T, Uemoto S, Nishi E.  Serum Nardilysin, a Surrogate Marker for Epithelial-Mesenchymal Transition, Predicts Prognosis of Intrahepatic Cholangiocarcinoma after Surgical Resection  Clin Cancer Res  2019  25(2):619-628  PubMed ID: 30352908
14890  Maishi N, Kikuchi H, Sato M, Nagao-Kitamoto H, Annan DA, Baba S, Hojo T, Yanagiya M, Ohba Y, Ishii G, Masutomi K, Shinohara N, Hida Y, Hida K.  Development of Immortalized Human Tumor Endothelial Cells from Renal Cancer  Int J Mol Sci  2019  20(18):4595  PubMed ID: 31533313
9500  Kanda K, Sakamoto J, Matsumoto Y, Ikuta K, Goto N, Morita Y, Ohno M, Nishi K, Eto K, Kimura Y, Nakanishi Y, Ikegami K, Yoshikawa T, Fukuda A, Kawada K, Sakai Y, Ito A, Yoshida M, Kimura T, Chiba T, Nishi E, Seno H.  Nardilysin controls intestinal tumorigenesis through HDAC1/p53-dependent transcriptional regulation.  JCI Insight  2018  3:  PubMed ID: 29669932
10788  Koshizuka T, Kobayashi T, Ishioka K, Suzutani T.  Herpesviruses possess conserved proteins for interaction with Nedd4 family ubiquitin E3 ligases.  Sci Rep  2018  8:4447  PubMed ID: 29535361
10808  Mochimaru Y, Negishi J, Murakami S, Musha S, Sato K, Okajima F, Tomura H.  Metals Differentially Activate Ovarian Cancer G Protein-Coupled Receptor 1 in Various Species.  Zool. Sci.  2018  35:109-114  PubMed ID: 29623784
10817  Yamashita W, Takahashi M, Kikkawa T, Gotoh H, Osumi N, Ono K, Nomura T.  Conserved and divergent functions of Pax6 underlie species-specific neurogenic patterns in the developing amniote brain.  Development  2018  145:  PubMed ID: 29661783
11042  Shigenori Inagaki; Masakazu Agetsuma; Takeharu Nagai  A novel fiber-free technique for brain activity imaging in multiple freely behaving mice  SPIE BiOS  2018   
11080  Wang Y, Cao L, Lee CY, Matsuo T, Wu K, Asher G, Tang L, Saitoh T, Russell J, Klewe-Nebenius D, Wang L, Soya S, Hasegawa E, Cherasse Y, Zhou J, Li Y, Wang T, Zhan X, Miyoshi C, Irukayama Y, Cao J, Meeks JP, Gautron L, Wang Z, Sakurai K, Funato H, Sakurai T, Yanagisawa M, Nagase H, Kobayakawa R, Kobayakawa K, Beutler B, Liu Q.  Large-scale forward genetics screening identifies Trpa1 as a chemosensor for predator odor-evoked innate fear behaviors.  Nat Commun  2018  9(1):2041  PubMed ID: 29795268
11137  Iuchi K, Morisada Y, Yoshino Y, Himuro T, Saito Y, Murakami T, Hisatomi H.  Cold atmospheric-pressure nitrogen plasma induces the production of reactive nitrogen species and cell death by increasing intracellular calcium in HEK293T cells.  Arch. Biochem. Biophys.  2018  654:136-145  PubMed ID: 30026027
11144  Funakohi-Tago M, Sakata T, Fujiwara S, Sakakura A, Sugai T, Tago K, Tamura H.  Hydroxytyrosol butyrate inhibits 6-OHDA-induced apoptosis through activation of the Nrf2/HO-1 axis in SH-SY5Y cells.  Eur. J. Pharmacol.  2018  834:246-256  PubMed ID: 30053409
11189  Kawaguchi M, Tani T, Hombu R, Ieda N, Nakagawa H.  Development and cellular application of visible-light-controllable HNO releasers based on caged Piloty's acid.  Chem. Commun. (Camb.)  2018  54(73):10371-10374  PubMed ID: 30152479
11205  Shiozawa Y, Malcovati L, Galli A, Sato-Otsubo A, Kataoka K, Sato Y, Watatani Y, Suzuki H, Yoshizato T, Yoshida K, Sanada M, Makishima H, Shiraishi Y, Chiba K, Hellstrom-Lindberg E, Miyano S, Ogawa S, Cazzola M.  Aberrant splicing and defective mRNA production induced by somatic spliceosome mutations in myelodysplasia.  Nat Commun  2018    PubMed ID: 30194306
11222  Ageta H, Ageta-Ishihara N, Hitachi K, Karayel O, Onouchi T, Yamaguchi H, Kahyo T, Hatanaka K, Ikegami K, Yoshioka Y, Nakamura K, Kosaka N, Nakatani M, Uezumi A, Ide T, Tsutsumi Y, Sugimura H, Kinoshita M, Ochiya T, Mann M, Setou M, Tsuchida K.  UBL3 modification influences protein sorting to small extracellular vesicles.  Nat Commun  2018    PubMed ID: 30258067
11233  Aoshima K, Fukui Y, Gulay KCM, Erdemsurakh O, Morita A, Kobayashi A, Kimura T.  Notch2 signal is required for the maintenance of canine hemangiosarcoma cancer stem cell-like cells.  BMC Vet. Res.  2018    PubMed ID: 30285832
11156  Ito S, Kayukawa N, Ueda T, Taniguchi H, Morioka Y, Hongo F, Ukimura O.  MRGBP promotes AR-mediated transactivation of KLK3 and TMPRSS2 via acetylation of histone H2A.Z in prostate cancer cells.  Biochim Biophys Acta Gene Regul Mech  2018    PubMed ID: 30076933
11112  Niino T, Tago K, Yasuda D, Takahashi K, Mashino T, Tamura H, Funakoshi-Tago M.  A 5-hydroxyoxindole derivative attenuates LPS-induced inflammatory responses by activating the p38-Nrf2 signaling axis.  Biochem. Pharmacol.  2018  155:182-197  PubMed ID: 29940171
11217  Matsuura R, Kaji H, Tomioka A, Sato T, Narimatsu H, Moriwaki Y, Misawa H, Imai K, Tsuji S.  Identification of mesothelioma-specific sialylated epitope recognized with monoclonal antibody SKM9-2 in a mucin-like membrane protein HEG1.  Sci Rep  2018    PubMed ID: 30250045
11313  Kamiki H, Matsugo H, Kobayashi T, Ishida H, Takenaka-Uema A, Murakami S, Horimoto T.  A PB1-K577E Mutation in H9N2 Influenza Virus Increases Polymerase Activity and Pathogenicity in Mice.  Viruses  2018    PubMed ID: 30463209
11343  Saeki E, Yasuhira S, Shibazaki M, Tada H, Doita M, Masuda T, Maesawa C.  Involvement of C-terminal truncation mutation of kinesin-5 in resistance to kinesin-5 inhibitor.  PLoS ONE  2018    PubMed ID: 30557316
11370  Xu P, Kai C, Kawasaki S, Kobayashi Y, Yamamoto K, Tsujikawa M, Hayashi R, Nishida K.  A New in Vitro Model of GDLD by Knocking Out TACSTD2 and Its Paralogous Gene EpCAM in Human Corneal Epithelial Cells.  Transl Vis Sci Technol  2018    PubMed ID: 30619650
4118  Kandori S, Kojima T, Matsuoka T, Yoshino T, Sugiyama A, Nakamura E, Shimazui T, Funakoshi Y, Kanaho Y, Nishiyama H.  Phospholipase D2 promotes disease progression of renal cell carcinoma through the induction of angiogenin.  Cancer Sci.  2018    PubMed ID: 29660846
4119  Hirose Y, Onishi T, Miura S, Hatazawa Y, Kamei Y.  Vitamin D Attenuates FOXO1-Target Atrophy Gene Expression in C2C12 Muscle Cells.  J. Nutr. Sci. Vitaminol.  2018    PubMed ID: 29962435
4120  Miyagawa Y, Matsushita Y, Suzuki H, Komatsu M, Yoshimaru T, Kimura R, Yanai A, Honda J, Tangoku A, Sasa M, Miyoshi Y, Katagiri T.  Frequent downregulation of LRRC26 by epigenetic alterations is involved in the malignant progression of triple-negative breast cancer.  Int. J. Oncol.  2018    PubMed ID: 29512727
4121  Kumeta M, Panina Y, Yamazaki H, Takeyasu K, Yoshimura SH.  N-terminal dual lipidation-coupled molecular targeting into the primary cilium.  Genes Cells  2018    PubMed ID: 29900630
4122  Kato Y, Ninomiya K, Ohashi K, Tomida S, Makimoto G, Watanabe H, Kudo K, Matsumoto S, Umemura S, Goto K, Ichihara E, Ninomiya T, Kubo T, Sato A, Hotta K, Tabata M, Toyooka S, Maeda Y, Kiura K.  Combined effect of cabozantinib and gefitinib in crizotinib-resistant lung tumors harboring ROS1 fusions.  Cancer Sci.  2018    PubMed ID: 30053332
4279  Ito S, Ueno A, Ueda T, Nakagawa H, Taniguchi H, Kayukawa N, Fujihara-Iwata A, Hongo F, Okihara K, Ukimura O.  CNPY2 inhibits MYLIP-mediated AR protein degradation in prostate cancer cells.  Oncotarget  2018    PubMed ID: 29707137
4465  Watanabe Y, Arai Y, Kawashita N, Ibrahim MS, Elgendy EM, Daidoji T, Kajikawa J, Hiramatsu H, Sriwilaijaroen N, Ono T, Takagi T, Takahashi K, Shioda T, Matsumoto K, Suzuki Y, Nakaya T.  Characterization of H5N1 Influenza Virus Quasispecies with Adaptive Hemagglutinin Mutations from Single-Virus Infections of Human Airway Cells.  J. Virol.  2018  92(11)  PubMed ID: 29563293
4478  Omachi K, Kamura M, Teramoto K, Kojima H, Yokota T, Kaseda S, Kuwazuru J, Fukuda R, Koyama K, Matsuyama S, Motomura K, Shuto T, Suico MA, Kai H.  A Split-Luciferase-Based Trimer Formation Assay as a High-throughput Screening Platform for Therapeutics in Alport Syndrome.  Cell Chem Biol  2018  25(5):634-643.e4  PubMed ID: 29526710
9128  Asuka Yoshida, Ryoko Kawabata, Tomoyuki Honda, Kouji Sakai, Yasushi Ami, Takemasa Sakaguchi, Takashi Irie  A Single Amino Acid Substitution Within the Paramyxovirus Sendai Virus Nucleoprotein Is a Critical Determinant for Production of Interferon-Beta-Inducing Copyback-Type Defective Interfering Genomes  J Virol  2018  92 (5)   PubMed ID: 29237838
14555  Iwai K, Yaguchi M, Nishimura K, Yamamoto Y, Tamura T, Nakata D, Dairiki R, Kawakita Y, Mizojiri R, Ito Y, Asano M, Maezaki H, Nakayama Y, Kaishima M, Hayashi K, Teratani M, Miyakawa S, Iwatani M, Miyamoto M, Klein MG, Lane W, Snell G, Tjhen R, He X, Pulukuri S, Nomura T.  Anti-tumor efficacy of a novel CLK inhibitor via targeting RNA splicing and MYC-dependent vulnerability  EMBO Mol Med  2018  10(6):e8289  PubMed ID: 29769258
14599  Senga S, Kawaguchi K, Kobayashi N, Ando A, Fujii H.  A novel fatty acid-binding protein 5-estrogen-related receptor α signaling pathway promotes cell growth and energy metabolism in prostate cancer cells  Oncotarget  2018  9(60):31753-31770  PubMed ID: 30167092
14909  Iijima K, Kobayashi J, Ishizaka Y.  Structural alteration of DNA induced by viral protein R of HIV-1 triggers the DNA damage response  Retrovirology  2018  15(1):8  PubMed ID: 29338752
15050  Kawabata Galbraith K, Fujishima K, Mizuno H, Lee SJ, Uemura T, Sakimura K, Mishina M, Watanabe N, Kengaku M.  MTSS1 Regulation of Actin-Nucleating Formin DAAM1 in Dendritic Filopodia Determines Final Dendritic Configuration of Purkinje Cells  Cell Rep  2018  24(1):95-106.e9  PubMed ID: 29972794
15300  Matsumoto N, Sekiya M, Tohyama K, Ishiyama-Matsuura E, Sun-Wada GH, Wada Y, Futai M, Nakanishi-Matsui M.  Essential Role of the a3 Isoform of V-ATPase in Secretory Lysosome Trafficking via Rab7 Recruitmen  Sci Rep  2018  ;8(1):6701  PubMed ID: 29712939
7011  Saito F, Hirayasu K, Satoh T, Wang CW, Lusingu J, Arimori T, Shida K, Palacpac NMQ, Itagaki S, Iwanaga S, Takashima E, Tsuboi T, Kohyama M, Suenaga T, Colonna M, Takagi J, Lavstsen T, Horii T, Arase H.  Immune evasion of Plasmodium falciparum by RIFIN via inhibitory receptors.  Nature  2017  552:101-105  PubMed ID: 29186116
9875  Chung J, Aburaya S, Aoki W, Ueda M.  Molecular changes in appearance of a cancer cell among normal HEK293T cells.  J. Biosci. Bioeng.  2017  123:281-286  PubMed ID: 27777049
10003  Takayama I, Tanabe H, Nishiyama T, Ito H, Amizuka N, Li M, Katsube KI, Kii I, Kudo A.  Periostin is required for matricellular localization of CCN3 in periodontal ligament of mice.  J Cell Commun Signal  2017  11:5-13  PubMed ID: 28013443
10065  Matsui T, Hori A, Hamako J, Matsushita F, Ozeki Y, Sakurai Y, Hayakawa M, Matsumoto M, Fujimura Y.  Mutant botrocetin-2 inhibits von Willebrand factor-induced platelet agglutination.  J. Thromb. Haemost.  2017  15:538-548  PubMed ID: 28071872
10081  Tsukamoto T, Chiba Y, Nakazaki A, Ishikawa Y, Nakane Y, Cho Y, Yotsu-Yamashita M, Nishikawa T, Wakamori M, Konoki K.  Inhibition of veratridine-induced delayed inactivation of the voltage-sensitive sodium channel by synthetic analogs of crambescin B.  Bioorg. Med. Chem. Lett.  2017  27:1247-1251  PubMed ID: 28143690
10100  Mori J, Tanikawa C, Ohnishi N, Funauchi Y, Toyoshima O, Ueda K, Matsuda K.  EPSIN 3, A Novel p53 Target, Regulates the Apoptotic Pathway and Gastric Carcinogenesis.  Neoplasia  2017  19:185-195  PubMed ID: 28152424
10115  Hang Q, Isaji T, Hou S, Wang Y, Fukuda T, Gu J.  A Key Regulator of Cell Adhesion: Identification and Characterization of Important N-Glycosylation Sites on Integrin α5 for Cell Migration.  Mol. Cell. Biol.  2017  37:  PubMed ID: 28167607
10136  Kawaguchi Y, Nariki H, Kawamoto N, Kanehiro Y, Miyazaki S, Suzuki M, Magari M, Tokumitsu H, Kanayama N.  SRSF1-3 contributes to diversification of the immunoglobulin variable region gene by promoting accumulation of AID in the nucleus.  Biochem. Biophys. Res. Commun.  2017  485:261-266  PubMed ID: 28235482
10163  Wada Y, Orba Y, Sasaki M, Kobayashi S, Carr MJ, Nobori H, Sato A, Hall WW, Sawa H.  Discovery of a novel antiviral agent targeting the nonstructural protein 4 (nsP4) of chikungunya virus.  Virology  2017  505:102-112  PubMed ID: 28236746
10164  Yamagata K, Kobayashi A.  The cysteine-rich domain of TET2 binds preferentially to mono- and dimethylated histone H3K36.  J. Biochem.  2017  161:327-330  PubMed ID: 28130413
10175  Tatebe H, Murayama S, Yonekura T, Hatano T, Richter D, Furuya T, Kataoka S, Furuita K, Kojima C, Shiozaki K.  Substrate specificity of TOR complex 2 is determined by a ubiquitin-fold domain of the Sin1 subunit.  Elife  2017  6:  PubMed ID: 28264193
10218  Guo L, Elcioglu NH, Mizumoto S, Wang Z, Noyan B, Albayrak HM, Yamada S, Matsumoto N, Miyake N, Nishimura G, Ikegawa S.  Identification of biallelic EXTL3 mutations in a novel type of spondylo-epi-metaphyseal dysplasia.  J. Hum. Genet.  2017  62:797-801  PubMed ID: 28331220
10232  Hashimoto H, Suda Y, Miyashita T, Ochiai A, Tsuboi M, Masutomi K, Kiyono T, Ishii G.  A novel method to generate single-cell-derived cancer-associated fibroblast clones.  J. Cancer Res. Clin. Oncol.  2017  143:1409-1419  PubMed ID: 28364361
10235  Goyal S, Suzuki T, Li JR, Maeda S, Kishima M, Nishimura H, Shimizu Y, Suzuki H.  RUNX1 induces DNA replication independent active DNA demethylation at SPI1 regulatory regions.  BMC Mol. Biol.  2017  18:9  PubMed ID: 28376714
10341  Hiwa R, Ohmura K, Arase N, Jin H, Hirayasu K, Kohyama M, Suenaga T, Saito F, Terao C, Atsumi T, Iwatani H, Mimori T, Arase H.  Myeloperoxidase/HLA Class II Complexes Recognized by Autoantibodies in Microscopic Polyangiitis.  Arthritis Rheumatol  2017  69:2069-2080  PubMed ID: 28575531
10390  Takahashi Y, Tanikawa C, Miyamoto T, Hirata M, Wang G, Ueda K, Komatsu T, Matsuda K.  Regulation of tubular recycling endosome biogenesis by the p53-MICALL1 pathway.  Int. J. Oncol.  2017  51:724-736  PubMed ID: 28714518
10428  Ishii T, Homma K, Mano A, Akagi T, Shigematsu Y, Shimoda Y, Inoue H, Kakinuma Y, Kaneda M.  Novel channel-mediated choline transport in cholinergic neurons of the mouse retina.  J. Neurophysiol.  2017  118:1952-1961  PubMed ID: 28701543
10456  Morita K, Maeda S, Suzuki K, Kiyose H, Taniguchi J, Liu PP, Sugiyama H, Adachi S, Kamikubo Y.  Paradoxical enhancement of leukemogenesis in acute myeloid leukemia with moderately attenuated RUNX1 expressions.  Blood Adv  2017  1:1440-1451  PubMed ID: 29296785
10541  Oda K, Oda T, Matoba Y, Sato M, Irie T, Sakaguchi T.  Structural analysis of the STAT1:STAT2 heterodimer revealed the mechanism of Sendai virus C protein-mediated blockade of type 1 interferon signaling.  J. Biol. Chem.  2017  292:19752-19766  PubMed ID: 28978648
10548  Hirano K, Namihira M.  FAD influx enhances neuronal differentiation of human neural stem cells by facilitating nuclear localization of LSD1.  FEBS Open Bio  2017  7:1932-1942  PubMed ID: 29226080
10637  Yamamura T, Nozu K, Miyoshi Y, Nakanishi K, Fujimura J, Horinouchi T, Minamikawa S, Mori N, Fujimaru R, Nakanishi K, Ninchoji T, Kaito H, Mariko TI, Morioka I, Matsuo M, Iijima K.  An in vitro splicing assay reveals the pathogenicity of a novel intronic variant in ATP6V0A4 for autosomal recessive distal renal tubular acidosis.  BMC Nephrol  2017  18:353  PubMed ID: 29202719
10642  Suzuki T, Maeda S, Furuhata E, Shimizu Y, Nishimura H, Kishima M, Suzuki H.  A screening system to identify transcription factors that induce binding site-directed DNA demethylation.  Epigenetics Chromatin  2017  10:60  PubMed ID: 29221486
4545  Shichita T, Ito M, Morita R, Komai K, Noguchi Y, Ooboshi H, Koshida R, Takahashi S, Kodama T, Yoshimura A.  MAFB prevents excess inflammation after ischemic stroke by accelerating clearance of damage signals through MSR1.  Nat. Med.  2017  23(6):723-732  PubMed ID: 28394332
4548  Meng H, Yamashita C, Shiba-Fukushima K, Inoshita T, Funayama M, Sato S, Hatta T, Natsume T, Umitsu M, Takagi J, Imai Y, Hattori N.  Loss of Parkinson's disease-associated protein CHCHD2 affects mitochondrial crista structure and destabilizes cytochrome c.  Nat Commun  2017  8:15500  PubMed ID: 28589937
5434  Nagasato AI, Yamashita H, Matsuo M, Ueda K, Kioka N.  The distribution of vinculin to lipid rafts plays an important role in sensing stiffness of extracellular matrix.  Biosci Biotechnol Biochem  2017  81(6):1136-1147  PubMed ID: 28485208
9498  Jaerin Sohn, Megumu Takahashi, Shinichiro Okamoto, Yoko Ishida, Takahiro Furuta, Hiroyuki Hioki  A Single Vector Platform for High-Level Gene Transduction of Central Neurons: Adeno-Associated Virus Vector Equipped With the Tet-Off System  PLoS One  2017  12(1):e0169611  PubMed ID: 28060929
12287  Shigenori Inagaki, Hidekazu Tsutsui, Kazushi Suzuki, Masakazu Agetsuma, Yoshiyuki Arai, Yuka Jinno, Guirong Bai, Matthew J Daniels, Yasushi Okamura, Tomoki Matsuda, Takeharu Nagai   Genetically encoded bioluminescent voltage indicator for multi-purpose use in wide range of bioimaging  Sci Rep  2017  7:42398  PubMed ID: 28205521
13814  Nakano T, Kanai Y, Amano Y, Yoshimoto T, Matsubara D, Shibano T, Tamura T, Oguni S, Katashiba S, Ito T, Murakami Y, Fukayama M, Murakami T, Endo S, Niki T.  Establishment of highly metastatic KRAS mutant lung cancer cell sublines in long-term three-dimensional low attachment cultures  PLoS Onec  2017  12(8):e0181342  PubMed ID: 28786996
13978  Fujitani M, Zhang S, Fujiki R, Fujihara Y, Yamashita T.  A chromosome 16p13.11 microduplication causes hyperactivity through dysregulation of miR-484/protocadherin-19 signaling  Mol Psychiatry  2017  22(3):364-374  PubMed ID: 27378146
14236  Okumura N, Kitahara M, Okuda H, Hashimoto K, Ueda E, Nakahara M, Kinoshita S, Young RD, Quantock AJ, Tourtas T, Schlötzer-Schrehardt U, Kruse F, Koizumi N.  Sustained Activation of the Unfolded Protein Response Induces Cell Death in Fuchs' Endothelial Corneal Dystrophy  Invest Ophthalmol Vis Sci  2017  58(9):3697-3707  PubMed ID: 28727885
14257  Senga Y, Imamura H, Miyafusa T, Watanabe H, Honda S.  AlphaScreen-based homogeneous assay using a pair of 25-residue artificial proteins for high-throughput analysis of non-native IgG  Sci Rep  2017  7(1):12466  PubMed ID: 28963557
14433  Endo H, Tanaka S, Imamura K, Adegawa S, Kikuta S, Sato R.  Cry toxin specificities of insect ABCC transporters closely related to lepidopteran ABCC2 transporters  Peptides  2017  98:86-92  PubMed ID: 28416297
14594  Kano D, Nakagami Y, Kurihara H, Hosokawa S, Zenda S, Kusumoto M, Fujii H, Kaneta T, Saito S, Uesawa Y, Kagaya H.  Development of a double-stranded siRNA labelling method by using 99m Tc and single photon emission computed tomography imaging  J Drug Target  2017  25(2):172-178  PubMed ID: 27588821
14624  Tsukamoto T, Chiba Y, Wakamori M, Yamada T, Tsunogae S, Cho Y, Sakakibara R, Imazu T, Tokoro S, Satake Y, Adachi M, Nishikawa T, Yotsu-Yamashita M, Konoki K.  Differential binding of tetrodotoxin and its derivatives to voltage-sensitive sodium channel subtypes (Na v 1.1 to Na v 1.7)  Br J Pharmacol  2017  174(21):3881-3892  PubMed ID: 28832970
14704  Wu DC, Wang SSW, Liu CJ, Wuputra K, Kato K, Lee YL, Lin YC, Tsai MH, Ku CC, Lin WH, Wang SW, Kishikawa S, Noguchi M, Wu CC, Chen YT, Chai CY, Lin CS, Kuo KK, Yang YH, Miyoshi H, Nakamura Y, Saito S, Nagata K, Lin CS, Yokoyama KK.  Reprogramming Antagonizes the Oncogenicity of HOXA13-Long Noncoding RNA HOTTIP Axis in Gastric Cancer Cells  Stem Cells  2017  35(10):2115-2128  PubMed ID: 28782268
14749  Kikuta S, Watanabe SJ, Sato R, Gusev O, Nesmelov A, Sogame Y, Cornette R, Kikawada T.  Towards water-free biobanks: long-term dry-preservation at room temperature of desiccation-sensitive enzyme luciferase in air-dried insect cells  Sci Rep  2017  7(1):6540  PubMed ID: 28747745
14759  Kobayashi JI, Hirasawa H, Ozawa T, Ozawa T, Takeda H, Fujimori Y, Nakanishi O, Kamada N, Ikeda T.  Synthesis and optimization of novel α-phenylglycinamides as selective TRPM8 antagonists  Bioorg Med Chem  2017  25(2):727-742  PubMed ID: 27964995
14767  Elgendy EM, Arai Y, Kawashita N, Daidoji T, Takagi T, Ibrahim MS, Nakaya T, Watanabe Y.  Identification of polymerase gene mutations that affect viral replication in H5N1 influenza viruses isolated from pigeons  J Gen Virol   2017  98(1):6-17  PubMed ID: 27926816
14777  Shigenori Inagaki, Masakazu Agetsuma, Shinya Ohara, Toshio Iijima, Tetsuichi Wazawa, Yoshiyuki Arai, Takeharu Nagai  In vivo brain activity imaging of interactively locomoting mice  bioRxiv   2017  October 15, 2017 
7048  Suzuki K, Kimura T, Shinoda H, Bai G, Daniels MJ, Arai Y, Nakano M, Nagai T.  Five colour variants of bright luminescent protein for real-time multicolour bioimaging.  Nat Commun  2016  7:13718  PubMed ID: 27966527
7056  Funato H, Miyoshi C, Fujiyama T, Kanda T, Sato M, Wang Z, Ma J, Nakane S, Tomita J, Ikkyu A, Kakizaki M, Hotta-Hirashima N, Kanno S, Komiya H, Asano F, Honda T, Kim SJ, Harano K, Muramoto H, Yonezawa T, Mizuno S, Miyazaki S, Connor L, Kumar V, Miura I, Suzuki T, Watanabe A, Abe M, Sugiyama F, Takahashi S, Sakimura K, Hayashi Y, Liu Q, Kume K, Wakana S, Takahashi JS, Yanagisawa M.  Forward-genetics analysis of sleep in randomly mutagenized mice.  Nature  2016  539:378-383  PubMed ID: 27806374
7060  Kanda S, Yanagitani K, Yokota Y, Esaki Y, Kohno K.  Autonomous translational pausing is required for XBP1u mRNA recruitment to the ER via the SRP pathway.  Proc. Natl. Acad. Sci. U.S.A.  2016  113:E5886-E5895  PubMed ID: 27651490
7062  Hashimoto T, Horikawa DD, Saito Y, Kuwahara H, Kozuka-Hata H, Shin-I T, Minakuchi Y, Ohishi K, Motoyama A, Aizu T, Enomoto A, Kondo K, Tanaka S, Hara Y, Koshikawa S, Sagara H, Miura T, Yokobori S, Miyagawa K, Suzuki Y, Kubo T, Oyama M, Kohara Y, Fujiyama A, Arakawa K, Katayama T, Toyoda A, Kunieda T.  Extremotolerant tardigrade genome and improved radiotolerance of human cultured cells by tardigrade-unique protein.  Nat Commun  2016  7:12808  PubMed ID: 27649274
7063  Morita S, Noguchi H, Horii T, Nakabayashi K, Kimura M, Okamura K, Sakai A, Nakashima H, Hata K, Nakashima K, Hatada I.  Targeted DNA demethylation in vivo using dCas9-peptide repeat and scFv-TET1 catalytic domain fusions.  Nat. Biotechnol.  2016  34:1060-1065  PubMed ID: 27571369
7069  Kataoka K, Shiraishi Y, Takeda Y, Sakata S, Matsumoto M, Nagano S, Maeda T, Nagata Y, Kitanaka A, Mizuno S, Tanaka H, Chiba K, Ito S, Watatani Y, Kakiuchi N, Suzuki H, Yoshizato T, Yoshida K, Sanada M, Itonaga H, Imaizumi Y, Totoki Y, Munakata W, Nakamura H, Hama N, Shide K, Kubuki Y, Hidaka T, Kameda T, Masuda K, Minato N, Kashiwase K, Izutsu K, Takaori-Kondo A, Miyazaki Y, Takahashi S, Shibata T, Kawamoto H, Akatsuka Y, Shimoda K, Takeuchi K, Seya T, Miyano S, Ogawa S.  Aberrant PD-L1 expression through 3'-UTR disruption in multiple cancers.  Nature  2016  534:402-6  PubMed ID: 27281199
7133  Ichijo Y, Mochimaru Y, Azuma M, Satou K, Negishi J, Nakakura T, Oshima N, Mogi C, Sato K, Matsuda K, Okajima F, Tomura H.  Two zebrafish G2A homologs activate multiple intracellular signaling pathways in acidic environment.  Biochem. Biophys. Res. Commun.  2016  469:81-86  PubMed ID: 26614909
7262  Kikuta S, Hou BH, Sato R, Frommer WB, Kikawada T.  FRET sensor-based quantification of intracellular trehalose in mammalian cells.  Biosci. Biotechnol. Biochem.  2016  80:162-5  PubMed ID: 26214383
9560  Hagiwara A, Ogiwara K, Takahashi T.  Expression of Membrane Progestin Receptors (mPRs) in Granulosa Cells of Medaka Preovulatory Follicles.  Zool. Sci.  2016  33:98-105  PubMed ID: 26853875
9627  Koguchi T, Tanikawa C, Mori J, Kojima Y, Matsuda K.  Regulation of myo-inositol biosynthesis by p53-ISYNA1 pathway.  Int. J. Oncol.  2016  48:2415-24  PubMed ID: 27035231
9649  Tsuchiya M, Niwa Y, Simizu S.  N-glycosylation of R-spondin1 at Asn137 negatively regulates its secretion and Wnt/β-catenin signaling-enhancing activity.  Oncol Lett  2016  11:3279-3286  PubMed ID: 27123103
9664  Tanaka H, Fujiwara H, Ochi F, Tanimoto K, Casey N, Okamoto S, Mineno J, Kuzushima K, Shiku H, Sugiyama T, Barrett AJ, Yasukawa M.  Development of Engineered T Cells Expressing a Chimeric CD16-CD3ζ Receptor to Improve the Clinical Efficacy of Mogamulizumab Therapy Against Adult T-Cell Leukemia.  Clin. Cancer Res.  2016  22:4405-16  PubMed ID: 27091408
9671  Hirayasu K, Saito F, Suenaga T, Shida K, Arase N, Oikawa K, Yamaoka T, Murota H, Chibana H, Nakagawa I, Kubori T, Nagai H, Nakamaru Y, Katayama I, Colonna M, Arase H.  Microbially cleaved immunoglobulins are sensed by the innate immune receptor LILRA2.  Nat Microbiol  2016  1:16054  PubMed ID: 27572839
9783  Khanom R, Nguyen CT, Kayamori K, Zhao X, Morita K, Miki Y, Katsube K, Yamaguchi A, Sakamoto K.  Keratin 17 Is Induced in Oral Cancer and Facilitates Tumor Growth.  PLoS ONE  2016  11:e0161163  PubMed ID: 27512993
9793  Yamaura K, Kiyonaka S, Numata T, Inoue R, Hamachi I.  Discovery of allosteric modulators for GABAA receptors by ligand-directed chemistry.  Nat. Chem. Biol.  2016  12:822-30  PubMed ID: 27526031
9807  Kobayashi T, Yagi Y, Nakamura T.  Development of Genome Engineering Tools from Plant-Specific PPR Proteins Using Animal Cultured Cells.  Methods Mol. Biol.  2016  1469:147-55  PubMed ID: 27557692
9843  Kondoh Y, Honda K, Hiranuma S, Hayashi T, Shimizu T, Watanabe N, Osada H.  Comparative chemical array screening for p38γ/δ MAPK inhibitors using a single gatekeeper residue difference between p38α/β and p38γ/δ.  Sci Rep  2016  6:29881  PubMed ID: 27431267
9845  Hazawa M, Yasuda T, Saotome-Nakamura A, Tomiyama K, Obara C, Goto T, Tajima K.  Intra- and extracellular plasminogen activator inhibitor-1 regulate effect of vitronectin against radiation-induced endothelial cell death.  Vascul. Pharmacol.  2016  87:150-158  PubMed ID: 27650166
9846  Hang Q, Isaji T, Hou S, Zhou Y, Fukuda T, Gu J.  N-Glycosylation of integrin α5 acts as a switch for EGFR-mediated complex formation of integrin α5β1 to α6β4.  Sci Rep  2016  6:33507  PubMed ID: 27641064
9908  Kurita K, Maeda M, Mansour MA, Kokuryo T, Uehara K, Yokoyama Y, Nagino M, Hamaguchi M, Senga T.  TRIP13 is expressed in colorectal cancer and promotes cancer cell invasion.  Oncol Lett  2016  12:5240-5246  PubMed ID: 28105232
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10012  Ohtsuka T, Sakaguchi M, Yamamoto H, Tomida S, Takata K, Shien K, Hashida S, Miyata-Takata T, Watanabe M, Suzawa K, Soh J, Youyi C, Sato H, Namba K, Torigoe H, Tsukuda K, Yoshino T, Miyoshi S, Toyooka S.  Interaction of cytokeratin 19 head domain and HER2 in the cytoplasm leads to activation of HER2-Erk pathway.  Sci Rep  2016  6:39557  PubMed ID: 28008968
10015  Hirayama S, Hori Y, Benedek Z, Suzuki T, Kikuchi K.  Fluorogenic probes reveal a role of GLUT4 N-glycosylation in intracellular trafficking.  Nat. Chem. Biol.  2016  12:853-9  PubMed ID: 27547921
10016  Hou S, Hang Q, Isaji T, Lu J, Fukuda T, Gu J.  Importance of membrane-proximal N-glycosylation on integrin β1 in its activation and complex formation.  FASEB J.  2016  30:4120-4131  PubMed ID: 27565712
12288  Kung-Kai Kuo, King-Teh Lee, Ker-Kong Chen, Ya-Han Yang, Ying-Chu Lin, Ming-Ho Tsai, Kenly Wuputra, Yen-Liang Lee, Chia-Chen Ku, Hiroyuki Miyoshi, Yukio Nakamura, Shigeo Saito, Chun-Chieh Wu, Chee-Yin Chai, Richard Eckner, Chen-Lung Steve Lin, Sophie S-W Wang, Deng-Chyang Wu, Chang-Shen Lin, Kazunari K Yokoyama  Positive Feedback Loop of OCT4 and c-JUN Expedites Cancer Stemness in Liver Cancer  Stem Cells  2016  34(11):2613-2624  PubMed ID: 27341307
12627  Elmansuri AZ, Tanino MA, Mahabir R, Wang L, Kimura T, Nishihara H, Kinoshita I, Dosaka-Akita H, Tsuda M, Tanaka S.  Novel signaling collaboration between TGF-β and adaptor protein Crk facilitates EMT in human lung cancer  Oncotarget   2016  7(19):27094-107  PubMed ID: 27027347
12670  Mori J, Tanikawa C, Funauchi Y, Lo PH, Nakamura Y, Matsuda K.  Cystatin C as a p53-inducible apoptotic mediator that regulates cathepsin L activity  Cancer Sci  2016  107(3):298-306  PubMed ID: 26757339
12671  Lu J, Isaji T, Im S, Fukuda T, Kameyama A, Gu J.  Expression of N-Acetylglucosaminyltransferase III Suppresses α2,3-Sialylation, and Its Distinctive Functions in Cell Migration Are Attributed to α2,6-Sialylation Levels  J Biol Chem  2016  291(11):5708-20  PubMed ID: 26801611
12894  Sohn J, Okamoto S, Kataoka N, Kaneko T, Nakamura K, Hioki H.  Differential Inputs to the Perisomatic and Distal-Dendritic Compartments of VIP-Positive Neurons in Layer 2/3 of the Mouse Barrel Cortex  Front Neuroanat  2016  10:124  PubMed ID: 28066195
12923  Ryuzono S, Takase R, Oishi K, Ikeda A, Chigwechokha PK, Funahashi A, Komatsu M, Miyagi T, Shiozaki K.  Lysosomal localization of Japanese medaka (Oryzias latipes) Neu1 sialidase and its highly conserved enzymatic profiles with human  Gene  2016  575(2 Pt 2):513-523.  PubMed ID: 26432003
12933  Obayashi M, Yoshida M, Tsunematsu T, Ogawa I, Sasahira T, Kuniyasu H, Imoto I, Abiko Y, Xu D, Fukunaga S, Tahara H, Kudo Y, Nagao T, Takata T.  microRNA-203 suppresses invasion and epithelial-mesenchymal transition induction via targeting NUAK1 in head and neck cancer  Oncotarget  2016  7(7):8223-39  PubMed ID: 26882562
13460  Miyake T, Kumasawa K, Sato N, Takiuchi T, Nakamura H, Kimura T.  Soluble VEGF receptor 1 (sFLT1) induces non-apoptotic death in ovarian and colorectal cancer cells  Sci Rep  2016  6:24853  PubMed ID: 27103202
13471  Wang SS, Wuputra K, Liu CJ, Lin YC, Chen YT, Chai CY, Lin CS, Kuo KK, Tsai MH, Wang SW, Chen KK, Miyoshi H, Nakamura Y, Saito S, Hanafusa T, Wu DC, Lin CS, Yokoyama KK.  Oncogenic function of the homeobox A13-long noncoding RNA HOTTIP-insulin growth factor-binding protein 3 axis in human gastric cancer  Oncotarget  2016  7(24):36049-36064  PubMed ID: 27144338
14024  Yasuhira S, Shibazaki M, Nishiya M, Maesawa C.  Paclitaxel-induced aberrant mitosis and mitotic slippage efficiently lead to proliferative death irrespective of canonical apoptosis and p53  Cell Cycle  2016  15(23):3268-3277  PubMed ID: 27764550
14114  Sakamoto Y, Kanatsu J, Toh M, Naka A, Kondo K, Iida K.  The Dietary Isoflavone Daidzein Reduces Expression of Pro-Inflammatory Genes through PPARα/γ and JNK Pathways in Adipocyte and Macrophage Co-Cultures  PLoS One  2016  11(2):e0149676  PubMed ID: 26901838
14151  Hou S, Isaji T, Hang Q, Im S, Fukuda T, Gu J.  Distinct effects of β1 integrin on cell proliferation and cellular signaling in MDA-MB-231 breast cancer cells  Sci Rep  2016  6:18430  PubMed ID: 26728650
14157  Sakuma T, Nakade S, Sakane Y, Suzuki KT, Yamamoto T.  MMEJ-assisted gene knock-in using TALENs and CRISPR-Cas9 with the PITCh systems  Nat Protoc  2016  11(1):118-33  PubMed ID: 26678082
14158  Johmura Y, Sun J, Kitagawa K, Nakanishi K, Kuno T, Naiki-Ito A, Sawada Y, Miyamoto T, Okabe A, Aburatani H, Li S, Miyoshi I, Takahashi S, Kitagawa M, Nakanishi M.  SCF(Fbxo22)-KDM4A targets methylated p53 for degradation and regulates senescence  Nat Commun  2016  7:10574  PubMed ID: 26868148
14168  Kikuta S, Endo H, Tomita N, Takada T, Morita C, Asaoka K, Sato R.  Characterization of a ligand-gated cation channel based on an inositol receptor in the silkworm, Bombyx mori  Insect Biochem Mol Biol  2016  74:12-20  PubMed ID: 27132146
14176  Tetsuo Koshizuka, Keiichiro Tanaka, Tatsuo Suzutani  Degradation of host ubiquitin E3 ligase Itch by human cytomegalovirus UL42  Journal of General Virology  2016  97:196-208 
14950  Mang D, Shu M, Endo H, Yoshizawa Y, Nagata S, Kikuta S, Sato R.  Expression of a sugar clade gustatory receptor, BmGr6, in the oral sensory organs, midgut, and central nervous system of larvae of the silkworm Bombyx mori  Insect Biochem Mol Biol  2016  70:85-98  PubMed ID: 26721200
7180  Hang Q, Isaji T, Hou S, Im S, Fukuda T, Gu J.  Integrin α5 Suppresses the Phosphorylation of Epidermal Growth Factor Receptor and Its Cellular Signaling of Cell Proliferation via N-Glycosylation.  J. Biol. Chem.  2015  290:29345-60  PubMed ID: 26483551
7190  Kataoka K, Nagata Y, Kitanaka A, Shiraishi Y, Shimamura T, Yasunaga J, Totoki Y, Chiba K, Sato-Otsubo A, Nagae G, Ishii R, Muto S, Kotani S, Watatani Y, Takeda J, Sanada M, Tanaka H, Suzuki H, Sato Y, Shiozawa Y, Yoshizato T, Yoshida K, Makishima H, Iwanaga M, Ma G, Nosaka K, Hishizawa M, Itonaga H, Imaizumi Y, Munakata W, Ogasawara H, Sato T, Sasai K, Muramoto K, Penova M, Kawaguchi T, Nakamura H, Hama N, Shide K, Kubuki Y, Hidaka T, Kameda T, Nakamaki T, Ishiyama K, Miyawaki S, Yoon SS, Tobinai K, Miyazaki Y, Takaori-Kondo A, Matsuda F, Takeuchi K, Nureki O, Aburatani H, Watanabe T, Shibata T, Matsuoka M, Miyano S, Shimoda K, Ogawa S.  Integrated molecular analysis of adult T cell leukemia/lymphoma.  Nat. Genet.  2015  47:1304-15  PubMed ID: 26437031
7216  Aoki N, Yamaguchi S, Kitajima T, Takehara A, Katagiri-Nakagawa S, Matsui R, Watanabe D, Matsushima T, Homma KJ.  Critical role of the neural pathway from the intermediate medial mesopallium to the intermediate hyperpallium apicale in filial imprinting of domestic chicks (Gallus gallus domesticus).  Neuroscience  2015  308:115-24  PubMed ID: 26362886
7242  Okumura N, Minamiyama R, Ho LT, Kay EP, Kawasaki S, Tourtas T, Schlotzer-Schrehardt U, Kruse FE, Young RD, Quantock AJ, Kinoshita S, Koizumi N.  Involvement of ZEB1 and Snail1 in excessive production of extracellular matrix in Fuchs endothelial corneal dystrophy.  Lab. Invest.  2015  95:1291-304  PubMed ID: 26302187
7252  Ichikawa T, Nakahata S, Fujii M, Iha H, Morishita K.  Loss of NDRG2 enhanced activation of the NF-κB pathway by PTEN and NIK phosphorylation for ATL and other cancer development.  Sci Rep  2015  5:12841  PubMed ID: 26269411
7263  Ichikawa T, Nakahata S, Tamura T, Manachai N, Morishita K.  The loss of NDRG2 expression improves depressive behavior through increased phosphorylation of GSK3β.  Cell. Signal.  2015  27:2087-98  PubMed ID: 26208882
7274  Tohmonda T, Yoda M, Iwawaki T, Matsumoto M, Nakamura M, Mikoshiba K, Toyama Y, Horiuchi K.  IRE1α/XBP1-mediated branch of the unfolded protein response regulates osteoclastogenesis.  J. Clin. Invest.  2015  125:3269-79  PubMed ID: 26193638
7371  Kimura T, Endo S, Inui M, Saitoh S, Miyake K, Takai T.  Endoplasmic Protein Nogo-B (RTN4-B) Interacts with GRAMD4 and Regulates TLR9-Mediated Innate Immune Responses.  J. Immunol.  2015  194:5426-36  PubMed ID: 25917084
7393  Ito T, Hioki H, Sohn J, Okamoto S, Kaneko T, Iino S, Oliver DL.  Convergence of Lemniscal and Local Excitatory Inputs on Large GABAergic Tectothalamic Neurons.  J. Comp. Neurol.  2015  523:2277-96  PubMed ID: 25879870
7426  Nakazato R, Takarada T, Ikeno S, Nakamura S, Kutsukake T, Hinoi E, Yoneda Y.  Upregulation of Runt-Related Transcription Factor-2 Through CCAAT Enhancer Binding Protein-β Signaling Pathway in Microglial BV-2 Cells Exposed to ATP.  J. Cell. Physiol.  2015  230:2510-21  PubMed ID: 25802132
7435  Ebina H, Kanemura Y, Misawa N, Sakuma T, Kobayashi T, Yamamoto T, Koyanagi Y.  A high excision potential of TALENs for integrated DNA of HIV-based lentiviral vector.  PLoS ONE  2015  10:e0120047  PubMed ID: 25781496
7468  Masuda K, Chiyoda T, Sugiyama N, Segura-Cabrera A, Kabe Y, Ueki A, Banno K, Suematsu M, Aoki D, Ishihama Y, Saya H, Kuninaka S.  LATS1 and LATS2 phosphorylate CDC26 to modulate assembly of the tetratricopeptide repeat subcomplex of APC/C.  PLoS ONE  2015  10:e0118662  PubMed ID: 25723520
7514  Mochimaru Y, Azuma M, Oshima N, Ichijo Y, Satou K, Matsuda K, Asaoka Y, Nishina H, Nakakura T, Mogi C, Sato K, Okajima F, Tomura H.  Extracellular acidification activates ovarian cancer G-protein-coupled receptor 1 and GPR4 homologs of zebra fish.  Biochem. Biophys. Res. Commun.  2015  457:493-9  PubMed ID: 25576873
3744  Nakamura R, Oyama T, Tajiri R, Mizokami A, Namiki M, Nakamoto M, Ooi A.  Expression and regulatory effects on cancer cell behavior of NELL1 and NELL2 in human renal cell carcinoma.  Cancer Sci  2015  106(5):656-64  PubMed ID: 25726761
9488  Tadahiro Suenaga, Maki Matsumoto, Fuminori Arisawa, Masako Kohyama, Kouyuki Hirayasu, Yasuko Mori, Hisashi Arase  Sialic Acids on Varicella-Zoster Virus Glycoprotein B Are Required for Cell-Cell Fusion  J Biol Chem  2015  290(32):19833-43  PubMed ID: 26105052
14284  Bill A, Gutierrez A, Kulkarni S, Kemp C, Bonenfant D, Voshol H, Duvvuri U, Gaither LA.  ANO1/TMEM16A interacts with EGFR and correlates with sensitivity to EGFR-targeting therapy in head and neck cancer  Oncotarget  2015  6(11):9173-88  PubMed ID: 25823819
15063  Tanaka S, Tanaka J, Miwa Y, Horikawa DD, Katayama T, Arakawa K, Toyoda A, Kubo T, Kunieda T.  Novel mitochondria-targeted heat-soluble proteins identified in the anhydrobiotic Tardigrade improve osmotic tolerance of human cells  PLoS One  2015  10(2):e0118272  PubMed ID: 25675104
15189  Shinmyo Y, Asrafuzzaman Riyadh M, Ahmed G, Bin Naser I, Hossain M, Takebayashi H, Kawasaki H, Ohta K, Tanaka H.  Draxin from neocortical neurons controls the guidance of thalamocortical projections into the neocortex  Nat Commun  2015  6:10232  PubMed ID: 26659141
15213  Suzuki Y, Kiyokage E, Sohn J, Hioki H, Toida K.  Structural basis for serotonergic regulation of neural circuits in the mouse olfactory bulb  J Comp Neurol   2015  523(2):262-80  PubMed ID: 25234191
15222  Ohishi K, Toume K, Arai MA, Koyano T, Kowithayakorn T, Mizoguchi T, Itoh M, Ishibashi M.  9-Hydroxycanthin-6-one, a β-Carboline Alkaloid from Eurycoma longifolia, Is the First Wnt Signal Inhibitor through Activation of Glycogen Synthase Kinase 3β without Depending on Casein Kinase 1α  J Nat Prod  2015  78(5):1139-46  PubMed ID: 25905468
15239  Wakimoto T, Uchida K, Mimura K, Kanagawa T, Mehandjiev TR, Aoshima H, Kokubo K, Mitsuda N, Yoshioka Y, Tsutsumi Y, Kimura T, Yanagihara I.  Hydroxylated fullerene: a potential antiinflammatory and antioxidant agent for preventing mouse preterm birth  Am J Obstet Gynecol  2015  213(5):708.e1-9  PubMed ID: 26196453
15258  Yamanishi M, Narazaki H, Asano T.  Melatonin overcomes resistance to clofarabine in two leukemic cell lines by increased expression of deoxycytidine kinase  Exp Hematol  2015  43(3):207-14  PubMed ID: 25461250
15452  Konoki K, Suga Y, Fuwa H, Yotsu-Yamashita M, Sasaki M.  Evaluation of gambierol and its analogs for their inhibition of human Kv1.2 and cytotoxicity  Bioorg Med Chem Lett  2015  ;25(3):514-8  PubMed ID: 25556093
7579  Suzuki-Nakagawa C, Nishimura M, Tsukamoto T, Aoyama S, Ebihara A, Suzuki F, Nakagawa T.  Participation of the extracellular domain in (pro)renin receptor dimerization.  Biochem. Biophys. Res. Commun.  2014  444:461-6  PubMed ID: 24472541
5836  Saito K, Sakaguchi M, Iioka H, Matsui M, Nakanishi H, Huh NH, Kondo E.  Coxsackie and adenovirus receptor is a critical regulator for the survival and growth of oral squamous carcinoma cells.  Oncogene  2014  33(10):1274-86  PubMed ID: 23503462
14940  Okumura N, Hirano H, Numata R, Nakahara M, Ueno M, Hamuro J, Kinoshita S, Koizumi N.  Cell surface markers of functional phenotypic corneal endothelial cells  Invest Ophthalmol Vis Sci  2014  55(11):7610-8  PubMed ID: 25389199
6082  Ohnishi H, Sasaki H, Nakamura Y, Kato S, Ando K, Narimatsu H, Tachibana K.  Regulation of cell shape and adhesion by CD34  Cell Adh Migr  2013  7(5):426-33  PubMed ID: 24036614
10938  Ayami Yamaguchi 1, Sae Tanaka, Shiho Yamaguchi, Hirokazu Kuwahara, Chizuko Takamura, Shinobu Imajoh-Ohmi, Daiki D Horikawa, Atsushi Toyoda, Toshiaki Katayama, Kazuharu Arakawa, Asao Fujiyama, Takeo Kubo, Takekazu Kunieda  Two Novel Heat-Soluble Protein Families Abundantly Expressed in an Anhydrobiotic Tardigrade  PLoS One  2012  7(8):e44209  PubMed ID: 22937162
7627  Ohue Y, Eikawa S, Okazaki N, Mizote Y, Isobe M, Uenaka A, Fukuda M, Old LJ, Oka M, Nakayama E.  Spontaneous antibody, and CD4 and CD8 T-cell responses against XAGE-1b (GAGED2a) in non-small cell lung cancer patients.  Int. J. Cancer  2011  131:E649-58  PubMed ID: 22109656
7710  Sakaguchi T, Irie T, Kuwayama M, Ueno T, Yoshida A, Kawabata R.  Analysis of interaction of Sendai virus V protein and melanoma differentiation-associated gene 5.  Microbiol. Immunol.  2011  55:760-7  PubMed ID: 21851384
7970  Narukawa M, Noga C, Ueno Y, Sato T, Misaka T, Watanabe T.  Evaluation of the bitterness of green tea catechins by a cell-based assay with the human bitter taste receptor hTAS2R39.  Biochem. Biophys. Res. Commun.  2011  405:620-5  PubMed ID: 21272567
12293  Ayako Kataoka, Yui Koga, Ayumi Uesugi, Hidetoshi Tozaki-Saitoh, Makoto Tsuda, Kazuhide Inoue  Involvement of vasodilator-stimulated phosphoprotein in UDP-induced microglial actin aggregation via PKC- and Rho-dependent pathways  Purinergic Signal  2011  7(4):403-11  PubMed ID: 21567128
8223  Mimasu S, Umezawa N, Sato S, Higuchi T, Umehara T, Yokoyama S.  Structurally designed trans-2-phenylcyclopropylamine derivatives potently inhibit histone demethylase LSD1/KDM1 .  Biochemistry  2010  49:6494-503  PubMed ID: 20568732
8240  Naoe H, Araki K, Nagano O, Kobayashi Y, Ishizawa J, Chiyoda T, Shimizu T, Yamamura K, Sasaki Y, Saya H, Kuninaka S.  The anaphase-promoting complex/cyclosome activator Cdh1 modulates Rho GTPase by targeting p190 RhoGAP for degradation.  Mol. Cell. Biol.  2010  30:3994-4005  PubMed ID: 20530197
8251  Shigemura T, Shiohara M, Tanaka M, Takeuchi K, Koike K.  Effect of the mutant microphthalmia-associated transcription factor found in Tietz syndrome on the in vitro development of mast cells.  J. Pediatr. Hematol. Oncol.  2010  32:442-7  PubMed ID: 20485200
11019  Shoudai Furuyama, Yoshinari Uehara, Bo Zhang, Yasuhiko Baba, Satomi Abe, Takahiro Iwamoto, Shin-Ichiro Miura, Keijiro Saku  Genotypic Effect of ABCG1 gene promoter -257T>G polymorphism on coronary artery disease severity in Japanese men  J Atheroscler Thromb  2009  16(3):194-200  PubMed ID: 19556716
11002  Hiroyuki Oshiumi 1, Yuzuru Suzuki, Misako Matsumoto, Tsukasa Seya  Regulator of complement activation (RCA) gene cluster in Xenopus tropicalis  Immunogenetics  2009  61(5):371-84  PubMed ID: 19319518
4887  Satoh T, Arii J, Suenaga T, Wang J, Kogure A, Uehori J, Arase N, Shiratori I, Tanaka S, Kawaguchi Y, Spear PG, Lanier LL, Arase H.  PILRalpha is a herpes simplex virus-1 entry coreceptor that associates with glycoprotein B.  Cell  2008  132(6):935-44  PubMed ID: 18358807
9071  Shiori Haga, Norio Yamamoto, Chikako Nakai-Murakami, Yoshiaki Osawa, Kenzo Tokunaga, Tetsutaro Sata, Naoki Yamamoto, Takehiko Sasazuki, Yukihito Ishizaka  Modulation of TNF-alpha-converting Enzyme by the Spike Protein of SARS-CoV and ACE2 Induces TNF-alpha Production and Facilitates Viral Entry  Proc Natl Acad Sci U S A  2008  105 (22), 7809-14  PubMed ID: 18490652
12783  Ueno K, Hiura M, Suehiro Y, Hazama S, Hirata H, Oka M, Imai K, Dahiya R, Hinoda Y.  Frizzled-7 as a potential therapeutic target in colorectal cancer  Neoplasia  2008  10(7):697-705  PubMed ID: 18592008
6478  Nakatani S, Mano H, Ryanghyok IM, Shimizu J, Wada M.  Excess magnesium inhibits excess calcium-induced matrix-mineralization and production of matrix gla protein (MGP) by ATDC5 cells.  Biochem Biophys Res Commun  2006  348(3):1157-62  PubMed ID: 16904632

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