戻る 戻る
細胞番号 : 細胞名
RCB2202 : 293T  update : 2023/12/11
細胞特性(Comment:英)A subline of 293. Expressing SV40 large T antigen.
細胞特性(日)293細胞株の亜株。SV40 large T 抗原を発現している。
使用条件(英)There is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC.
提供申込書類(英) Order Form(C-0005.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)  
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
提供申込書類(日) 依頼書C-0001.pdf   同意書(非営利学術目的)C-0003.pdf   同意書(営利目的)C-0003p.pdf  
提供同意書は、使用機関の種類や目的に応じて、非営利学術目的 (C-XXXX) と営利目的 (C-XXXXp) の2種類があります。該当する提供同意書をご使用ください(詳細)。特許等の取得及び商業利用等は事前に必ず cellbank.brc@riken.jp までご連絡ください。
提供手数料 手数料とお支払いについてはこちらをご覧ください。
細胞基本情報 寄託者 Miyoshi, Hiroyuki
寄託日 2005
元の細胞 HEK293
動物種 _human < Mammals
属名 Homo
種名 sapiens
採取組織 kidney
細胞分類 transformed
遺伝子改変 recombinant
外来遺伝子 SV40 large T antigen
細胞寿命 infinite
細胞形態 epithelial-like
Cellosaurus(Expasy) CVCL_0063
培地・試薬情報 培地・試薬一覧はこちらをご覧ください。
培養形態 Adherent cells
培地 DMEM (low glucose) + 10% FBS (heat inactivated)
抗生物質 Free
継代方法 0.25% Trypsin
継代密度 1 : 10 split
継代・培地交換頻度 Subculture : 2 times/week
培養最適温度 37 ℃
二酸化炭素濃度 5 %
凍結培地 Medium + 10% DMSO
凍結方法 Slow freezing
マイコプラズマ (-)
個体識別検査 OK
文献情報 Reference(英) 4件
Reference(日) 0件
利用者成果(英) 452件
利用者成果(日) 0件

3489  DuBridge RB, Tang P, Hsia HC, Leong PM, Miller JH, Calos MP.  Analysis of mutation in human cells by using an Epstein-Barr virus shuttle system.  Mol Cell Biol  1987  7(1):379-87  PubMed ID: 3031469   DOI: 10.1128/mcb.7.1.379
4972  Graham FL, Harrison T, Williams J.  Defective transforming capacity of adenovirus type 5 host-range mutants.  Virology  1978  86(1):10-21  PubMed ID: 664220   DOI: 10.1016/0042-6822(78)90003-x
2415  Harrison T, Graham F, Williams J  Host-range mutants of adenovirus type 5 defective for growth in HeLa cells.  Virology  1977  77:319-29  PubMed ID: 841862   DOI: 10.1016/0042-6822(77)90428-7
2414  Graham, F L, Smiley J, Russell, W C, Nairn R  Characteristics of a human cell line transformed by DNA from human adenovirus type 5.  J Gen Virol  1977  36:59-74  PubMed ID: 886304   DOI: 10.1099/0022-1317-36-1-59


17565  Arai Y, Yamanaka I, Okamoto T, Isobe A, Nakai N, Kamimura N, Suzuki T, Daidoji T, Ono T, Nakaya T, Matsumoto K, Okuzaki D, Watanabe Y.  Stimulation of interferon-β responses by aberrant SARS-CoV-2 small viral RNAs acting as retinoic acid-inducible gene-I agonists  iScience  2023  26(1):105742  PubMed ID: 36507221   DOI: 10.1016/j.isci.2022.105742
17804  Toshiki Takahashi, Jun Shirai, Miyo Matsuda, Sae Nakanaga, Shin Matsushita, Kei Wakita, Mizuki Hayashishita, Rigel Suzuki, Aya Noguchi, Naoto Yokota, and Hiroyuki Kawahara  Protein quality control machinery supports primary ciliogenesis by eliminating GDP-bound Rab8- family GTPases  iScience  2023      DOI: 10.1016/ j.isci.2023.106652
18094  Nakajima M, Kawahara R, Simizu S.  Cofilin promotes vasculogenic mimicry by regulating the actin cytoskeleton in human breast cancer cells  FEBS Lett  2023  597(8):1114-1124  PubMed ID: 36737242   DOI: 10.1002/1873-3468.14594
18098  Gohara Y, Tomonobu N, Kinoshita R, Futami J, Audebert L, Chen Y, Komalasari NLGY, Jiang F, Yoshizawa C, Murata H, Yamamoto KI, Watanabe M, Kumon H, Sakaguchi M.  Novel extracellular role of REIC/Dkk-3 protein in PD-L1 regulation in cancer cells  J Mol Med (Berl)   2023  101(4):431-447  PubMed ID: 36869893   DOI: 10.1007/s00109-023-02292-w
18106  Komalasari NLGY, Tomonobu N, Kinoshita R, Chen Y, Sakaguchi Y, Gohara Y, Jiang F, Yamamoto KI, Murata H, Ruma IMW, Sumardika IW, Zhou J, Yamauchi A, Kuribayashi F, Inoue Y, Toyooka S, Sakaguchi M.  Lysyl oxidase-like 4 exerts an atypical role in breast cancer progression that is dependent on the enzymatic activity that targets the cell-surface annexin A2  Front Oncol  2023  13:1142907  PubMed ID: 37091157   DOI: 10.3389/fonc.2023.1142907
18139  Hoshino N, Kanadome T, Takasugi T, Itoh M, Kaneko R, Inoue YU, Inoue T, Hirabayashi T, Watanabe M, Matsuda T, Nagai T, Tarusawa E, Yagi T.  Visualization of trans homophilic interaction of clustered protocadherin in neurons  Proc Natl Acad Sci U S A  2023  120(38):e2301003120  PubMed ID: 37695902   DOI: 10.1073/pnas.2301003120
18171  Kikuchi M, Takase S, Konuma T, Noritsugu K, Sekine S, Ikegami T, Ito A, Umehara T.  GAS41 promotes H2A.Z deposition through recognition of the N terminus of histone H3 by the YEATS domain  Proc Natl Acad Sci U S A  2023  120(43):e2304103120  PubMed ID: 37844223   DOI: 10.1073/pnas.2304103120
20922  Sasaki M, Tabata K, Kishimoto M, Itakura Y, Kobayashi H, Ariizumi T, Uemura K, Toba S, Kusakabe S, Maruyama Y, Iida S, Nakajima N, Suzuki T, Yoshida S, Nobori H, Sanaki T, Kato T, Shishido T, Hall WW, Orba Y, Sato A, Sawa H.  S-217622, a SARS-CoV-2 main protease inhibitor, decreases viral load and ameliorates COVID-19 severity in hamsters.  Sci Transl Med  2023  15(679):eabq4064  PubMed ID: 36327352   DOI: 10.1126/scitranslmed.abq4064
20993  Okamoto K, Kamikubo Y, Yamauchi K, Okamoto S, Takahashi M, Ishida Y, Koike M, Ikegaya Y, Sakurai T, Hioki H.  Specific AAV2/PHP.eB-mediated gene transduction of CA2 pyramidal cells via injection into the lateral ventricle.  Sci Rep  2023  13(1):323  PubMed ID: 36609635   DOI: 10.1038/s41598-022-27372-8
21011  Hiyamizu S, Qiu H, Vuolo L, Stevenson NL, Shak C, Heesom KJ, Hamada Y, Tsurumi Y, Chiba S, Katoh Y, Stephens DJ, Nakayama K.  Multiple interactions of the dynein-2 complex with the IFT-B complex are required for effective IFT.  J Cell Sci  2023    PubMed ID: 36632779   DOI: 10.1242/jcs.260462
21015  Shoji H, Kitao K, Miyazawa T, Nakagawa S.  Potentially reduced fusogenicity of syncytin-2 in New World monkeys.  FEBS Open Bio  2023    PubMed ID: 36647789   DOI: 10.1002/2211-5463.13555
21065  Morihiro K, Osumi H, Morita S, Hattori T, Baba M, Harada N, Ohashi R, Okamoto A.  Oncolytic Hairpin DNA Pair: Selective Cytotoxic Inducer through MicroRNA-Triggered DNA Self-Assembly.  J Am Chem Soc  2023  145(1):135-142  PubMed ID: 36538570   DOI: 10.1021/jacs.2c08974
21076  Sato M, Maishi N, Hida Y, Yanagawa-Matsuda A, Alam MT, Sakakibara-Konishi J, Nam JM, Onodera Y, Konno S, Hida K.  Angiogenic inhibitor pre-administration improves the therapeutic effects of immunotherapy.  Cancer Med  2023    PubMed ID: 36808261   DOI: 10.1002/cam4.5696
21092  Yoshimoto S, Suzuki T, Otani N, Takahashi D, Toshima K, Dohmae N, Simizu S.  Destabilization of vitelline membrane outer layer protein 1 homolog (VMO1) by C-mannosylation.  FEBS Open Bio  2023    PubMed ID: 36680395   DOI: 10.1002/2211-5463.13561
21101  Ota A, Morita H, Naganuma T, Miyamoto M, Jojima K, Nojiri K, Matsuda J, Kihara A.  Bifunctional DEGS2 has higher hydroxylase activity toward substrates with very-long-chain fatty acids in the production of phytosphingosine-ceramides.  J Biol Chem  2023  104603  PubMed ID: 36907437   DOI: 10.1016/j.jbc.2023.104603
17485  Tanikawa S, Ebisu Y, Sedlačík T, Semba S, Nonoyama T, Kurokawa T, Hirota A, Takahashi T, Yamaguchi K, Imajo M, Kato H, Nishimura T, Tanei ZI, Tsuda M, Nemoto T, Gong JP, Tanaka S.  Engineering of an electrically charged hydrogel implanted into a traumatic brain injury model for stepwise neuronal tissue reconstruction  Sci Rep  2023  13(1):2233  PubMed ID: 36788295   DOI: 10.1038/s41598-023-28870-z
21104  Kawano T, Kashiwagi M, Kanuka M, Chen CK, Yasugaki S, Hatori S, Miyazaki S, Tanaka K, Fujita H, Nakajima T, Yanagisawa M, Nakagawa Y, Hayashi Y.  ER proteostasis regulators cell-non-autonomously control sleep.  Cell Rep  2023  42(3):112267  PubMed ID: 36924492   DOI: 10.1016/j.celrep.2023.112267
21158  Tao F, Kitamura K, Hanada S, Sugimoto K, Furihata T, Kojima N.  Rapid and Stable Formation Method of Human Astrocyte Spheroid in a High Viscous Methylcellulose Medium and Its Functional Advantages.  Bioengineering (Basel)  2023  10(3)  PubMed ID: 36978740   DOI: 10.3390/bioengineering10030349
21159  Watanabe T, Narahari A, Bhardwaj E, Kuriyama K, Nishimura M, Izumi T, Fujimuro M, Ohno S.  Conserved cysteine residues in Kaposi's sarcoma herpesvirus ORF34 are necessary for viral production and viral pre-initiation complex formation.  bioRxiv  2023    PubMed ID: 36945456   DOI: 10.1101/2023.03.08.531831
21179  Noritsugu K, Suzuki T, Dodo K, Ohgane K, Ichikawa Y, Koike K, Morita S, Umehara T, Ogawa K, Sodeoka M, Dohmae N, Yoshida M, Ito A.  Lysine long-chain fatty acylation regulates the TEAD transcription factor.  Cell Rep  2023  112388  PubMed ID: 37060904   DOI: 10.1016/j.celrep.2023.112388
21219  Jojima K, Kihara A.  Metabolism of sphingadiene and characterization of the sphingadiene-producing enzyme FADS3.  Biochim Biophys Acta Mol Cell Biol Lipids  2023  1868(8):159335  PubMed ID: 37209771   DOI: 10.1016/j.bbalip.2023.159335
21222  Takahashi T, Shirai J, Matsuda M, Nakanaga S, Matsushita S, Wakita K, Hayashishita M, Suzuki R, Noguchi A, Yokota N, Kawahara H.  Protein quality control machinery supports primary ciliogenesis by eliminating GDP-bound Rab8-family GTPases.  iScience  2023  26(5):106652  PubMed ID: 37182096   DOI: 10.1016/j.isci.2023.106652
21248  Kasuga Y, Ouda R, Watanabe M, Sun X, Kimura M, Hatakeyama S, Kobayashi KS.  FBXO11 constitutes a major negative regulator of MHC class II through ubiquitin-dependent proteasomal degradation of CIITA.  Proc Natl Acad Sci U S A  2023  120(24):e2218955120  PubMed ID: 37279268   DOI: 10.1073/pnas.2218955120
21258  Nishi K, Yoshii A, Abell L, Zhou B, Frausto R, Ritterhoff J, McMillen TS, Sweet I, Wang Y, Gao C, Tian R.  Branched-chain keto acids inhibit mitochondrial pyruvate carrier and suppress gluconeogenesis in hepatocytes.  Cell Rep  2023  42(6):112641  PubMed ID: 37310861   DOI: 10.1016/j.celrep.2023.112641
21261  Hiyamizu S, Qiu H, Tsurumi Y, Hamada Y, Katoh Y, Nakayama K.  Dynein-2-driven intraciliary retrograde trafficking indirectly requires multiple interactions of IFT54 in the IFT-B complex with the dynein-2 complex.  Biol Open  2023    PubMed ID: 37309605   DOI: 10.1242/bio.059976
21265  Shimohata A, Rai D, Akagi T, Usui S, Ogiwara I, Kaneda M.  The intracellular C-terminal domain of mGluR6 contains ER retention motifs.  Mol Cell Neurosci  2023  103875  PubMed ID: 37352898   DOI: 10.1016/j.mcn.2023.103875
21270  Yamaguchi S, Kamino M, Hamamura M, Otsuguro KI.  The cytosolic N-terminal region of heterologously-expressed transmembrane channel-like protein 1 (TMC1) can be cleaved in HEK293 cells.  PLoS One  2023  18(6):e0287249  PubMed ID: 37352201   DOI: 10.1371/journal.pone.0287249
21278  Okada M, Shimizu K, Nakazato H, Yamasaki S, Fujii SI.  Detection of mutant antigen-specific T cell receptors against multiple myeloma for T cell engineering.  Mol Ther Methods Clin Dev  2023  29:541-555  PubMed ID: 37359417   DOI: 10.1016/j.omtm.2023.05.014
21285  Morishita K, Kondo J, Sakon D, Hayashibara A, Tamura I, Shimizu K, Takamatsu S, Murata K, Kamada Y, Miyoshi E.  Prohaptoglobin is a possible prognostic biomarker for colorectal cancer.  Biochem Biophys Res Commun  2023  672:72-80  PubMed ID: 37343317   DOI: 10.1016/j.bbrc.2023.06.017
21309  Tanaka Y, Morozumi A, Hirokawa N.  Nodal flow transfers polycystin to determine mouse left-right asymmetry.  Dev Cell  2023    PubMed ID: 37413993   DOI: 10.1016/j.devcel.2023.06.002
21312  Omata K, Nomura I, Hirata A, Yonezuka Y, Muto H, Kuriki R, Jimbo K, Ogasa K, Kato T.  Isolation and evaluation of erythroid progenitors in the livers of larval, froglet, and adult Xenopus tropicalis.  Biol Open  2023    PubMed ID: 37421150   DOI: 10.1242/bio.059862
21316  Matsuura-Suzuki E, Toh H, Iwasaki S.  Human-rabbit Hybrid Translation System to Explore the Function of Modified Ribosomes.  Bio Protoc  2023  13(13):e4714  PubMed ID: 37456340   DOI: 10.21769/BioProtoc.4714
21317  Tokuma H, Sakano D, Tanabe K, Tanizawa Y, Shiraki N, Kume S.  Selective proteasome degradation of C-terminally-truncated human WFS1 in pancreatic beta cells.  FEBS Open Bio  2023    PubMed ID: 37440664   DOI: 10.1002/2211-5463.13674
21326  Takahashi G, Miyaoka Y.  Large-scale single-cell cloning of genome-edited cultured human cells by On-chip SPiS.  STAR Protoc  2023  4(3):102364  PubMed ID: 37329509   DOI: 10.1016/j.xpro.2023.102364
21335  Goto M, Nishimura G, Sato H, Yamaguchi Y, Morimoto N, Hashimoto H, Takahashi N.  Pharmacological profile of upacicalcet, a novel positive allosteric modulator of calcium-sensing receptor, in vitro and in vivo.  Eur J Pharmacol  2023  175936  PubMed ID: 37541363   DOI: 10.1016/j.ejphar.2023.175936
21345  Komuro H, Shinohara S, Fukushima Y, Demachi-Okamura A, Muraoka D, Masago K, Matsui T, Sugita Y, Takahashi Y, Nishida R, Takashima C, Ohki T, Shigematsu Y, Watanabe F, Adachi K, Fukuyama T, Hamana H, Kishi H, Miura D, Tanaka Y, Onoue K, Onoguchi K, Yamashita Y, Stratford R, Clancy T, Yamaguchi R, Kuroda H, Doi K, Iwata H, Matsushita H.  Single-cell sequencing on CD8+ TILs revealed the nature of exhausted T cells recognizing neoantigen and cancer/testis antigen in non-small cell lung cancer.  J Immunother Cancer  2023  11(8)  PubMed ID: 37544663   DOI: 10.1136/jitc-2023-007180
21353  Kanadome T, Hoshino N, Nagai T, Yagi T, Matsuda T.  Visualization of trans-interactions of a protocadherin-α between processes originating from single neurons.  iScience  2023  26(7):107238  PubMed ID: 37534169   DOI: 10.1016/j.isci.2023.107238
21367  Lloyd DB, Thompson JF.  Transcriptional modulators affect in vivo protein binding to the low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase promoters.  J Biol Chem  2023  270(43):25812-8  PubMed ID: 7592765   DOI: 10.1074/jbc.270.43.25812
21373  Suzuki MM, Iijima K, Ogami K, Shinjo K, Murofushi Y, Xie J, Wang X, Kitano Y, Mamiya A, Kibe Y, Nishimura T, Ohka F, Saito R, Sato S, Kobayashi J, Yao R, Miyata K, Kataoka K, Suzuki HI, Kondo Y.  TUG1-mediated R-loop resolution at microsatellite loci as a prerequisite for cancer cell proliferation.  Nat Commun  2023  14(1):4521  PubMed ID: 37607907   DOI: 10.1038/s41467-023-40243-8
21382  Xu J, Hashino T, Tanaka R, Kawaguchi K, Yoshida H, Kataoka T.  The BCL-2 family protein BCL-RAMBO interacts and cooperates with GRP75 to promote its apoptosis signaling pathway.  Sci Rep  2023  13(1):14041  PubMed ID: 37640805   DOI: 10.1038/s41598-023-41196-0
21398  Kanao E, Ishida K, Mizuta R, Li Y, Imami K, Tanigawa T, Sasaki Y, Akiyoshi K, Adachi J, Otsuka K, Ishihama Y, Kubo T.  Rapid and Highly Efficient Purification of Extracellular Vesicles Enabled by a TiO2 Hybridized Spongy-like Polymer.  Anal Chem  2023    PubMed ID: 37703188   DOI: 10.1021/acs.analchem.3c03411
21416  Sogawa A, Komori R, Yanagitani K, Ohfurudono M, Tsuru A, Kadoi K, Kimata Y, Yoshida H, Kohno K.  Signal sequence-triage is activated by translocon obstruction sensed by an ER stress sensor IRE1α.  Cell Struct Funct  2023    PubMed ID: 37766570   DOI: 10.1247/csf.23072
21472  Takeuchi K, Tabe S, Takahashi K, Aoshima K, Matsuo M, Ueno Y, Furukawa Y, Yamaguchi K, Ohtsuka M, Morinaga S, Miyagi Y, Yamaguchi T, Tanimizu N, Taniguchi H.  Incorporation of human iPSC-derived stromal cells creates a pancreatic cancer organoid with heterogeneous cancer-associated fibroblasts.  Cell Rep  2023  42(11):113420  PubMed ID: 37955987   DOI: 10.1016/j.celrep.2023.113420
17502  Haraguchi-Suzuki K, Kawabata-Iwakawa R, Suzuki T, Suto T, Takazawa T, Saito S.  Local anesthetic lidocaine induces growth suppression of HeLa cells by decreasing and changing the cellular localization of the proliferation marker Ki-67  Genes Cells  2022  27(11):675-684  PubMed ID: 36074048   DOI: 10.1111/gtc.12983
17510  Miku Akishino, Yuko Aoki, Hajime Baba, Makio Asakawa, Yoichiro Hama, Susumu Mitsutake  Red algae-derived isofloridoside activates the sweet taste receptor T1R2/T1R3  Food Bioscience  2022  50:102186    DOI: 10.1016/j.fbio.2022.102186
17529  Tsukida K, Muramatsu SI, Osaka H, Yamagata T, Muramatsu K.  WDR45 variants cause ferrous iron loss due to impaired ferritinophagy associated with nuclear receptor coactivator 4 and WD repeat domain phosphoinositide interacting protein 4 reduction  Brain Commun  2022  4(6):fcac304  PubMed ID: 36751498   DOI: 10.1093/braincomms/fcac304
17581  Kamiki H, Murakami S, Nishikaze T, Hiono T, Igarashi M, Furuse Y, Matsugo H, Ishida H, Katayama M, Sekine W, Muraki Y, Takahashi M, Takenaka-Uema A, Horimoto T.  Influenza A Virus Agnostic Receptor Tropism Revealed Using a Novel Biological System with Terminal Sialic Acid Knockout Cells  J Virol  2022  96(15):e0041622  PubMed ID: 35862707   DOI: 10.1128/jvi.00416-22
17616  Yamashita F, Kaieda T, Shimomura T, Kawaguchi M, Lin CY, Johnson MD, Tanaka H, Kiwaki T, Fukushima T, Kataoka H.  Role of the polycystic kidney disease domain in matriptase chaperone activity and localization of hepatocyte growth factor activator inhibitor-1  FEBS J  2022  289(12):3422-3439  PubMed ID: 35020274   DOI: 10.1111/febs.16348
17620  Saito S, Funayama K, Kato W, Okuda M, Kawamoto M, Matsubara T, Sato T, Sato A, Otsuguro S, Sasaki M, Orba Y, Sawa H, Maenaka K, Shindo K, Imoto M, Arai MA.  Dihydromaniwamycin E, a Heat-Shock Metabolite from Thermotolerant Streptomyces sp. JA74, Exhibiting Antiviral Activity against Influenza and SARS-CoV-2 Viruses  J Nat Prod  2022  85(11):2583-2591  PubMed ID: 36223390   DOI: 10.1021/acs.jnatprod.2c00550
17651  Wei Z, Shimizu K, Sarii RS, Muthusinghe DS, Lokupathirage SMW, Nio-Kobayashi J, Yoshimatsu K.  Pathological Studies on Hantaan Virus-Infected Mice Simulating Severe Hemorrhagic Fever with Renal Syndrome  Viruses  2022  14(10):2247  PubMed ID: 36298802   DOI: 10.3390/v14102247
17675  Yamauchi K, Okamoto S, Ishida Y, Konno K, Hoshino K, Furuta T, Takahashi M, Koike M, Isa K, Watanabe M, Isa T, Hioki H.  Fluorochromized tyramide-glucose oxidase as a multiplex fluorescent tyramide signal amplification system for histochemical analysis  Sci Rep  2022  12(1):14807  PubMed ID: 36097273   DOI: 10.1038/s41598-022-19085-9
17714  Matsumura Y, To TK, Kunieda T, Kohno H, Kakutani T, Kubo T.  Mblk-1/E93, an ecdysone related-transcription factor, targets synaptic plasticity-related genes in the honey bee mushroom bodies  Sci Rep  2022  12(1):21367  PubMed ID: 36494426   DOI: 10.1038/s41598-022-23329-z
17783  Ohshima T, Yamamoto H, Sakamaki Y, Saito C, Mizushima N.  NCOA4 drives ferritin phase separation to facilitate macroferritinophagy and microferritinophagy  J Cell Biol  2022  221(10):e202203102  PubMed ID: 36066504   DOI: 10.1083/jcb.202203102
17788  Takeuchi Y, Ushimaru K, Kaneda K, Maruyama C, Ito T, Yamanaka K, Ogasawara Y, Katano H, Kato Y, Dairi T, Hamano Y.  First direct evidence for direct cell-membrane penetrations of polycationic homopoly(amino acid)s produced by bacteria  Commun Biol  2022  5(1):1132  PubMed ID: 36289442   DOI: 10.1038/s42003-022-04110-4
20207  Tsuji H, Ohmura K, Jin H, Naito R, Arase N, Kohyama M, Suenaga T, Sakakibara S, Kochi Y, Okada Y, Yamamoto K, Kikutani H, Morinobu A, Mimori T, Arase H.  Anti-dsDNA antibodies recognize DNA presented on HLA class II molecules of systemic lupus erythematosus risk alleles.  Arthritis Rheumatol  2022    PubMed ID: 34164946   DOI: 10.1002/art.41897
20452  Tanaka K, Kandori S, Sakka S, Nitta S, Tanuma K, Shiga M, Nagumo Y, Negoro H, Kojima T, Mathis BJ, Shimazui T, Watanabe M, Sato TA, Miyamoto T, Matsuzaka T, Shimano H, Nishiyama H.  ELOVL2 promotes cancer progression by inhibiting cell apoptosis in renal cell carcinoma.  Oncol Rep  2022  47(2)  PubMed ID: 34841437   DOI: 10.3892/or.2021.8234
20477  Arase N, Tsuji H, Takamatsu H, Jin H, Konaka H, Hamaguchi Y, Tonomura K, Kotobuki Y, Ueda-Hayakawa I, Matsuoka S, Hirano T, Yorifuji H, Murota H, Ohmura K, Nakashima R, Sato T, Kumanogoh A, Katayama I, Arase H, Fujimoto M.  Cell surface-expressed Ro52/IgG/HLA-DR complex is targeted by autoantibodies in patients with inflammatory myopathies.  J Autoimmun  2022  126:102774  PubMed ID: 34896887   DOI: 10.1016/j.jaut.2021.102774
20517  Qiu H, Tsurumi Y, Katoh Y, Nakayama K.  Combinations of deletion and missense variations of the dynein-2 DYNC2LI1 subunit found in skeletal ciliopathies cause ciliary defects.  Sci Rep  2022  12(1):31  PubMed ID: 34997029   DOI: 10.1038/s41598-021-03950-0
20522  Hiraiwa M, Fukasawa K, Iezaki T, Sabit H, Horie T, Tokumura K, Iwahashi S, Murata M, Kobayashi M, Suzuki A, Park G, Kaneda K, Todo T, Hirao A, Nakada M, Hinoi E.  SMURF2 phosphorylation at Thr249 modifies glioma stemness and tumorigenicity by regulating TGF-β receptor stability.  Commun Biol  2022  5(1):22  PubMed ID: 35017630   DOI: 10.1038/s42003-021-02950-0
20524  Nomura T, Nagao K, Shirai R, Gotoh H, Umeda M, Ono K.  Temperature sensitivity of Notch signaling underlies species-specific developmental plasticity and robustness in amniote brains.  Nat Commun  2022  13(1):96  PubMed ID: 35013223   DOI: 10.1038/s41467-021-27707-5
16114  Wuputra K, Tsai MH, Kato K, Yang YH, Pan JB, Ku CC, Noguchi M, Kishikawa S, Nakade K, Chen HL, Liu CJ, Nakamura Y, Kuo KK, Lin YC, Chan TF, Wu DC, Hou MF, Huang SK, Lin CS, Yokoyama KK.  Dimethyl sulfoxide stimulates the AhR-Jdp2 axis to control ROS accumulation in mouse embryonic fibroblasts  Cell Biol Toxicol  2022  Mar 15  PubMed ID: 33723743   DOI: 10.1007/s10565-021-09592-2
20588  Jin H, Kishida K, Arase N, Matsuoka S, Nakai W, Kohyama M, Suenaga T, Yamamoto K, Sasazuki T, Arase H.  Abrogation of self-tolerance by misfolded self-antigens complexed with MHC class II molecules.  Sci Adv  2022  8(9):eabj9867  PubMed ID: 35245125   DOI: 10.1126/sciadv.abj9867
20597  Murakami Y, Masaki M, Miyazaki S, Oketani R, Hayashi Y, Yanagisawa M, Honjoh S, Kano H.  Spectroscopic second and third harmonic generation microscopy using a femtosecond laser source in the third near-infrared (NIR-III) optical window.  Biomed Opt Express  2022  13(2):694-708  PubMed ID: 35284173   DOI: 10.1364/BOE.446273
20641  Miyajima Y, Noguchi S, Tanaka Y, Li JR, Nishimura H, Kishima M, Lim J, Furuhata E, Suzuki T, Kasukawa T, Suzuki H.  Prediction of transcription factors associated with DNA demethylation during human cellular development.  Chromosome Res  2022  30(1):109-121  PubMed ID: 35142952   DOI: 10.1007/s10577-022-09685-6
20659  Chino H, Yamasaki A, Ode KL, Ueda HR, Noda NN, Mizushima N.  Phosphorylation by casein kinase 2 enhances the interaction between ER-phagy receptor TEX264 and ATG8 proteins.  EMBO Rep  2022  e54801  PubMed ID: 35417087   DOI: 10.15252/embr.202254801
20702  Nashimoto Y, Matsushita F, Dijkstra JM, Nakamura Y, Akiyama H, Hamako J, Morita T, Araki S, Matsui T.  Bitiscetin-3, a Novel C-Type Lectin-like Protein Cloned from the Venom Gland of the Viper Bitis arietans, Induces Platelet Agglutination and Inhibits Binding of Von Willebrand Factor to Collagen.  Toxins (Basel)  2022  14(4)  PubMed ID: 35448845   DOI: 10.3390/toxins14040236
20704  Kamo H, Kawahara R, Simizu S.  Tyrosinase suppresses vasculogenic mimicry in human melanoma cells.  Oncol Lett  2022  23(5):169  PubMed ID: 35496574   DOI: 10.3892/ol.2022.13289
20713  Satoda Y, Noguchi T, Fujii T, Taniguchi A, Katoh Y, Nakayama K.  BROMI/TBC1D32 together with CCRK/CDK20 and FAM149B1/JBTS36 contributes to IFT turnaround involving ICK/CILK1.  Mol Biol Cell  2022  mbcE22030089  PubMed ID: 35609210   DOI: 10.1091/mbc.E22-03-0089
16502  Kamada H, Yasuhira S, Shibazaki M, Amano H, Maesawa C.  DUSP4 Inactivation Leads to Reduced Extracellular Signal‒Regulated Kinase Activity through Upregulation of DUSP6 in Melanoma Cells  J Invest Dermatol  2022  S0022-202X(22)00126-9  PubMed ID: 35189148   DOI: 10.1016/j.jid.2022.02.007
20729  Ishida Y, Tasaki K, Katoh Y, Nakayama K.  Molecular basis underlying the ciliary defects caused by IFT52 variations found in skeletal ciliopathies.  Mol Biol Cell  2022  mbcE22050188  PubMed ID: 35704471   DOI: 10.1091/mbc.E22-05-0188
16632  Hada M, Miura H, Tanigawa A, Matoba S, Inoue K, Ogonuki N, Hirose M, Watanabe N, Nakato R, Fujiki K, Hasegawa A, Sakashita A, Okae H, Miura K, Shikata D, Arima T, Shirahige K, Hiratani I, Ogura A.  Highly rigid H3.1/H3.2-H3K9me3 domains set a barrier for cell fate reprogramming in trophoblast stem cells  Genes Dev  2022  36(1-2):84-102  PubMed ID: 34992147   DOI: 10.1101/gad.348782.121
16658  Sasaki K, Suzuki M, Sonoda T, Schneider-Poetsch T, Ito A, Takagi M, Fujishiro S, Sohtome Y, Dodo K, Umehara T, Aburatani H, Shin-Ya K, Nakao Y, Sodeoka M, Yoshida M.  Visualization of the dynamic interaction between nucleosomal histone H3K9 tri-methylation and HP1α chromodomain in living cells  Cell Chem Biol  2022  S2451-9456(22)00198-2  PubMed ID: 35728598   DOI: 10.1016/j.chembiol.2022.05.006
16659  Matsuura-Suzuki E, Shimazu T, Takahashi M, Kotoshiba K, Suzuki T, Kashiwagi K, Sohtome Y, Akakabe M, Sodeoka M, Dohmae N, Ito T, Shinkai Y, Iwasaki S.  METTL18-mediated histidine methylation of RPL3 modulates translation elongation for proteostasis maintenance  Elife  2022  11:e72780  PubMed ID: 35674491   DOI: 10.7554/eLife.72780
20750  Yamada T, Fukasawa K, Horie T, Kadota T, Lyu J, Tokumura K, Ochiai S, Iwahashi S, Suzuki A, Park G, Ueda R, Yamamoto M, Kitao T, Shirahase H, Ochi H, Sato S, Iezaki T, Hinoi E.  The role of CDK8 in mesenchymal stem cells in controlling osteoclastogenesis and bone homeostasis.  Stem Cell Reports  2022    PubMed ID: 35777359   DOI: 10.1016/j.stemcr.2022.06.001
16732  Zhu Z, Kitano T, Morimatsu M, Tanaka A, Morioka R, Lin X, Orino K, Yoshikawa Y.  BRCA2 C-Terminal RAD51-Binding Domain Confers Resistance to DNA-Damaging Agents  Int J Mol Sci  2022  23(7):4060  PubMed ID: 35409418   DOI: 10.3390/ijms23074060
16747  Fujii K, Morita S, Mochizuki M, Shibuya-Takahashi R, Fujimori H, Yamaguchi K, Abe J, Yamazaki T, Imai T, Sugamura K, Yasuda J, Satoh K, Sato I, Saito-Koyama R, Fujishima F, Sasano H, Kato Y, Matsuura K, Asada Y, Tamai K.  Establishment of a monoclonal antibody against glycosylated CD271 specific for cancer cells in immunohistochemistry  Cancer Sci . 2022 Mar 28  2022  Mar 28  PubMed ID: 35343032   DOI: 10.1111/cas.15340
16748  Song W, Isaji T, Nakano M, Liang C, Fukuda T, Gu J.  O-GlcNAcylation regulates β1,4-GlcNAc-branched N-glycan biosynthesis via the OGT/SLC35A3/GnT-IV axis  FASEB J  2022  36(2):e22149  PubMed ID: 34981577   DOI: 10.1096/fj.202101520R
16749  Kitanishi T, Tashiro M, Kitanishi N, Mizuseki K.  Intersectional, anterograde transsynaptic targeting of neurons receiving monosynaptic inputs from two upstream regions  Commun Biol  2022  5(1):149  PubMed ID: 35190665   DOI: 10.1038/s42003-022-03096-3
16750  Otsuka K, Sawai-Ogawa M, Kihara A.  Formation of fatty alcohols-components of meibum lipids-by the fatty acyl-CoA reductase FAR2 is essential for dry eye prevention  FASEB J  2022  36(4):e22216  PubMed ID: 35238077   DOI: 10.1096/fj.202101733R
16765  Takahashi S, Shibutani S, Iwata H.  Nuclear-targeted 4E-BP1 is dephosphorylated, induces nuclear translocation of eIF4E, and alters mRNA translation  Exp Cell Res  2022  418(1):113246  PubMed ID: 35697076   DOI: 10.1016/j.yexcr.2022.113246
20788  Oishi T, Ito M, Koizumi S, Horikawa M, Yamamoto T, Yamagishi S, Yamasaki T, Sameshima T, Suzuki T, Sugimura H, Namba H, Kurozumi K.  Efficacy of HSV-TK/GCV system suicide gene therapy using SHED expressing modified HSV-TK against lung cancer brain metastases.  Mol Ther Methods Clin Dev  2022  26:253-265  PubMed ID: 35892087   DOI: 10.1016/j.omtm.2022.07.001
20822  Deai M, Oya R, Saso N, Tanaka A, Uchida I, Miyake Y, Tachihara R, Otsugu M, Mine A, Sato K, Tomura H.  Ethylenediaminetetraacetic acid (EDTA) enhances cAMP production in human TDAG8-expressing cells.  Biochem Biophys Res Commun  2022  626:15-20  PubMed ID: 35964552   DOI: 10.1016/j.bbrc.2022.07.110
17100  Izumi A, Yamamoto K, Kawaguchi M, Yamashita F, Fukushima T, Kiwaki T, Tanaka H, Yamashita Y, Kataoka H.  Insufficiency of hepatocyte growth factor activator inhibitor-1 confers lymphatic invasion of tongue carcinoma cells  Cancer Sci  2022  113(6):2179-2193  PubMed ID: 35332604   DOI: 10.1111/cas.15346
20836  Kashio M, Masubuchi S, Tominaga M.  Protein kinase C (PKC)-mediated phosphorylation of TRPM2 Thr738 counteracts the effect of cytosolic Ca2+ and elevates the temperature threshold.  J Physiol  2022    PubMed ID: 36042566   DOI: 10.1113/JP283350
20845  Zhou Z, Katoh Y, Nakayama K.  CEP19-RABL2-IFT-B axis controls BBSome-mediated ciliary GPCR export.  Mol Biol Cell  2022    PubMed ID: 36074075   DOI: 10.1091/mbc.E22-05-0161
20857  Nohara T, Ohno Y, Kihara A.  Impaired production of skin barrier lipid acylceramides and abnormal localization of PNPLA1 due to ichthyosis-causing mutations in PNPLA1.  J Dermatol Sci  2022  107(2):89-94  PubMed ID: 35970721   DOI: 10.1016/j.jdermsci.2022.07.008
20869  Lyu X, Imai S, Yamano T, Hanayama R.  Preventing SARS-CoV-2 Infection Using Anti-spike Nanobody-IFN-β Conjugated Exosomes.  Pharm Res  2022    PubMed ID: 36163411   DOI: 10.1007/s11095-022-03400-0
20873  Yamamura N, Mikkaichi T, Itokawa KI, Hoshi M, Damme K, Geigner S, Baumhauer C.  Mirogabalin, a novel α2δ ligand, is not a substrate of LAT1, but of PEPT1, PEPT2, OAT1, OAT3, OCT2, MATE1 and MATE2-K.  Xenobiotica  2022  1-42  PubMed ID: 36170033   DOI: 10.1080/00498254.2022.2129517
20880  Kanadome T, Hayashi K, Seto Y, Eiraku M, Nakajima K, Nagai T, Matsuda T.  Development of intensiometric indicators for visualizing N-cadherin interaction across cells.  Commun Biol  2022  5(1):1065  PubMed ID: 36207396   DOI: 10.1038/s42003-022-04023-2
20892  Mang D, Mayu K, Toyama T, Yamagishi T, Sato R.  BmGr4 responds to sucrose and glucose and expresses in tachykinin-related peptide-secreting enteroendocrine cells.  Insect Biochem Mol Biol  2022  103858  PubMed ID: 36244651   DOI: 10.1016/j.ibmb.2022.103858
20906  Nakazato A, Mochizuki M, Shibuya-Takahashi R, Fujimori H, Fujii K, Saijoh S, Morita S, Yamazaki T, Imai T, Sato I, Satoh K, Yamaguchi K, Sugamura K, Yasuda J, Matsuura K, Shojaku H, Asada Y, Tamai K.  RELA is required for CD271 expression and stem-like characteristics in hypopharyngeal cancer.  Sci Rep  2022  12(1):17751  PubMed ID: 36273237   DOI: 10.1038/s41598-022-22736-6
20912  Kotani N, Nakano T, Kuwahara R.  Host cell membrane proteins located near SARS-CoV-2 spike protein attachment sites are identified using proximity labeling and proteomic analysis.  J Biol Chem  2022  298(11):102500  PubMed ID: 36152751   DOI: 10.1016/j.jbc.2022.102500
20914  Wang TW, Johmura Y, Suzuki N, Omori S, Migita T, Yamaguchi K, Hatakeyama S, Yamazaki S, Shimizu E, Imoto S, Furukawa Y, Yoshimura A, Nakanishi M.  Blocking PD-L1-PD-1 improves senescence surveillance and ageing phenotypes.  Nature  2022    PubMed ID: 36323784   DOI: 10.1038/s41586-022-05388-4
20926  Akiyama M, Unoki T, Aoki H, Nishimura A, Shinkai Y, Warabi E, Nishiyama K, Furumoto Y, Anzai N, Akaike T, Nishida M, Kumagai Y.  Cystine-dependent antiporters buffer against excess intracellular reactive sulfur species-induced stress.  Redox Biol  2022  57:102514  PubMed ID: 36279630   DOI: 10.1016/j.redox.2022.102514
17337  Sekine W, Takenaka-Uema A, Kamiki H, Ishida H, Matsugo H, Murakami S, Horimoto T.  Adaptation of the H7N2 Feline Influenza Virus to Human Respiratory Cell Culture  Viruses  2022  14(5):1091  PubMed ID: 35632832   DOI: 10.3390/v14051091
20971  Tatsumi A, Hirakochi H, Inoue S, Tanaka Y, Furuno H, Ikeda M, Ishibashi S, Taguchi T, Yamamoto K, Onishi I, Sachs Z, Largaespada DA, Kitagawa M, Kurata M.  Identification of NRAS Downstream Genes with CRISPR Activation Screening.  Biology (Basel)  2022  11(11)  PubMed ID: 36358254   DOI: 10.3390/biology11111551
20975  Moriyama H, Moriyama M, Ozawa T, Tsuruta D, Hayakawa T.  Differentiation of Human Adipose-Derived Mesenchymal Stromal/Stem Cells into Insulin-Producing Cells with A Single Tet-Off Lentiviral Vector System.  Cell J  2022  24(12):705-714  PubMed ID: 36527342   DOI: 10.22074/cellj.2022.557533.1063
20998  Ozono T, Kimura Y, Suenaga T, Beck G, Jinno J, Aguirre C, Ikenaka K, Krainc D, Mochizuki H, Arase H.  Extracellular transportation of α-synuclein by HLA class II molecules.  Biochem Biophys Res Commun  2022  644:25-33  PubMed ID: 36621149   DOI: 10.1016/j.bbrc.2022.12.082
21033  Takahashi TM, Hirano A, Kanda T, Saito VM, Ashitomi H, Tanaka KZ, Yokoshiki Y, Masuda K, Yanagisawa M, Vogt KE, Tokuda T, Sakurai T.  Optogenetic induction of hibernation-like state with modified human Opsin4 in mice.  Cell Rep Methods  2022  2(11):100336  PubMed ID: 36452866   DOI: 10.1016/j.crmeth.2022.100336
21037  Takahashi M, Kobayashi T, Mizuma H, Yamauchi K, Okamoto S, Okamoto K, Ishida Y, Koike M, Watanabe M, Isa T, Hioki H.  Preferential arborization of dendrites and axons of parvalbumin- and somatostatin-positive GABAergic neurons within subregions of the mouse claustrum.  Neurosci Res  2022    PubMed ID: 36574563   DOI: 10.1016/j.neures.2022.11.008
17361  Hirose Y, Shindo N, Mori M, Onitsuka S, Isogai H, Hamada R, Hiramoto T, Ochi J, Takahashi D, Ueda T, Caaveiro JMM, Yoshida Y, Ohdo S, Matsunaga N, Toba S, Sasaki M, Orba Y, Sawa H, Sato A, Kawanishi E, Ojida A.  Discovery of Chlorofluoroacetamide-Based Covalent Inhibitors for Severe Acute Respiratory Syndrome Coronavirus 2 3CL Protease  J Med Chem  2022  65(20):13852-13865  PubMed ID: 36229406   DOI: 10.1021/acs.jmedchem.2c01081
21141  Suenaga T, Mori Y, Suzutani T, Arase H.  Siglec-7 mediates varicella-zoster virus infection by associating with glycoprotein B.  Biochem Biophys Res Commun  2022  607:67-72  PubMed ID: 35367830   DOI: 10.1016/j.bbrc.2022.03.060
17694  Furuta T, Yamauchi K, Okamoto S, Takahashi M, Kakuta S, Ishida Y, Takenaka A, Yoshida A, Uchiyama Y, Koike M, Isa K, Isa T, Hioki H.  Multi-scale light microscopy/electron microscopy neuronal imaging from brain to synapse with a tissue clearing method, Sca l eSF  iScience  2021  25(1):103601  PubMed ID: 35106459   DOI: 10.1016/j.isci.2021.103601
12798  Johmura Y, Yamanaka T, Omori S, Wang TW, Sugiura Y, Matsumoto M, Suzuki N, Kumamoto S, Yamaguchi K, Hatakeyama S, Takami T, Yamaguchi R, Shimizu E, Ikeda K, Okahashi N, Mikawa R, Suematsu M, Arita M, Sugimoto M, Nakayama KI, Furukawa Y, Imoto S, Nakanishi M.  Senolysis by glutaminolysis inhibition ameliorates various age-associated disorders  Science  2021  371(6526):265-270  PubMed ID: 33446552   DOI: 10.1126/science.abb5916
13320  Matsumoto N, Sekiya M, Fujimoto Y, Haga S, Sun-Wada GH, Wada Y, Nakanishi-Matsui M.  Functional complementation of V-ATPase a subunit isoforms in osteoclasts.  J Biochem  2021  169(4):459-466  PubMed ID: 33135054   DOI: 10.1093/jb/mvaa118
13345  Daifu T, Mikami M, Hiramatsu H, Iwai A, Umeda K, Noura M, Kubota H, Masuda T, Furuichi K, Takasaki S, Noguchi Y, Morita K, Bando T, Hirata M, Kataoka TR, Nakahata T, Kuwahara Y, Iehara T, Hosoi H, Takita J, Sugiyama H, Adachi S, Kamikubo Y.  Suppression of malignant rhabdoid tumors through Chb-M'-mediated RUNX1 inhibition.  Pediatr Blood Cancer  2021    PubMed ID: 33180377   DOI: 10.1002/pbc.28789
13351  Matsumoto Y, Kishida K, Matsumoto M, Matsuoka S, Kohyama M, Suenaga T, Arase H.  A TCR-like antibody against a proinsulin-containing fusion peptide ameliorates type 1 diabetes in NOD mice.  Biochem Biophys Res Commun  2021    PubMed ID: 33208230   DOI: 10.1016/j.bbrc.2020.11.019
13463  Shota Someya et al  Tryptophan Metabolism Regulates Proliferative Capacity of Human Pluripotent Stem Cells  iScienc  2021  24  PubMed ID: 33615198   DOI: 10.1016/j.isci.2021.102090
20008  Umaba R, Kitanishi T, Mizuseki K.  Monosynaptic connection from the subiculum to medial mammillary nucleus neurons projecting to the anterior thalamus and Gudden's ventral tegmental nucleus.  Neurosci Res  2021    PubMed ID: 33476683   DOI: 10.1016/j.neures.2021.01.006
20053  Takafuji S, Mori T, Nishimura N, Yamamoto N, Uemura S, Nozu K, Terui K, Toki T, Ito E, Muramatsu H, Takahashi Y, Matsuo M, Yamamura T, Iijima K.  Usefulness of functional splicing analysis to confirm precise disease pathogenesis in Diamond-Blackfan anemia caused by intronic variants in RPS19.  Pediatr Hematol Oncol  2021  1-16  PubMed ID: 33622161   DOI: 10.1080/08880018.2021.1887984
20060  Nishiike Y, Miyazoe D, Togawa R, Yokoyama K, Nakasone K, Miyata M, Kikuchi Y, Kamei Y, Todo T, Ishikawa-Fujiwara T, Ohno K, Usami T, Nagahama Y, Okubo K.  Estrogen receptor 2b is the major determinant of sex-typical mating behavior and sexual preference in medaka.  Curr Biol  2021    PubMed ID: 33639108   DOI: 10.1016/j.cub.2021.01.089
13513  Takahashi Y, Wake H, Sakaguchi M, Yoshii Y, Teshigawara K, Wang D, Nishibori M.  Histidine-Rich Glycoprotein Stimulates Human Neutrophil Phagocytosis and Prolongs Survival through CLEC1A  J Immunol   2021  206(4):737-750  PubMed ID: 33452125   DOI: 10.4049/jimmunol.2000817
20067  Aizawa N, Fujimori Y, Nakanishi O, Hayashi T, Goi Y, Kobayashi JI, Fujita T.  Efficacy of the combination of KPR-5714, a novel transient receptor potential melastatin 8 (TRPM8) antagonist, and β3-adrenoceptor agonist or anticholinergic agent on bladder dysfunction in rats with bladder overactivity.  Eur J Pharmacol  2021  173995  PubMed ID: 33675781   DOI: 10.1016/j.ejphar.2021.173995
20068  Nakamura R, Oyama T, Inokuchi M, Ishikawa S, Hirata M, Kawashima H, Ikeda H, Dobashi Y, Ooi A.  Neural EGFL like 2 expressed in myoepithelial cells and suppressed breast cancer cell migration.  Pathol Int  2021    PubMed ID: 33657249   DOI: 10.1111/pin.13087
13640  Fujita K, Koide N, Somiya M, Kuroda S, Hinuma S.  A regulatory role of scavenger receptor class B type 1 in endocytosis and lipid droplet formation induced by liposomes containing phosphatidylethanolamine in HEK293T cells  Biochim Biophys Acta Mol Cell Res  2021  1868(1):118859  PubMed ID: 32956759   DOI: 10.1016/j.bbamcr.2020.118859
20083  Hama K, Fujiwara Y, Hayama T, Ozawa T, Nozawa K, Matsuda K, Hashiguchi Y, Yokoyama K.  Very long-chain fatty acids are accumulated in triacylglycerol and nonesterified forms in colorectal cancer tissues.  Sci Rep  2021  11(1):6163  PubMed ID: 33731797   DOI: 10.1038/s41598-021-85603-w
20103  McKee HK, Kajiwara C, Yamaguchi T, Ishii Y, Shimizu N, Ohara A, Tateda K.  Clostridioides difficile toxins enhanced the in vitro production of CXC chemokine ligand 2 and tumor necrosis factor-α via Toll-like receptors in macrophages.  J Med Microbiol  2021  70(4)  PubMed ID: 33830910   DOI: 10.1099/jmm.0.001342
13898  Takuma Kitanishi, Ryoko Umaba, Kenji Mizuseki  Robust information routing by dorsal subiculum neurons  Sci Adv  2021  7(11):eabf1913  PubMed ID: 33692111   DOI: 10.1126/sciadv.abf1913
13913  Rai D, Akagi T, Shimohata A, Ishii T, Gangi M, Maruyama T, Wada-Kiyama Y, Ogiwara I, Kaneda M.  Involvement of the C-terminal domain in cell surface localization and G-protein coupling of mGluR6  J Neurochem  2021  158(4):837-848  PubMed ID: 33067823   DOI: 10.1111/jnc.15217
20114  Ojiro I, Nishio H, Yamazaki-Ito T, Nakano S, Ito S, Toyohara Y, Hiramoto T, Terada Y, Ito K.  Trp-Trp acts as a multi-functional blocker for human bitter taste receptors, hTAS2R14, hTAS2R16, hTAS2R43, and hTAS2R46.  Biosci Biotechnol Biochem  2021    PubMed ID: 33844825   DOI: 10.1093/bbb/zbab061
20138  Nagumo Y, Kandori S, Tanuma K, Nitta S, Chihara I, Shiga M, Hoshi A, Negoro H, Kojima T, Mathis BJ, Funakoshi Y, Nishiyama H.  PLD1 promotes tumor invasion by regulation of MMP-13 expression via NF-κB signaling in bladder cancer.  Cancer Lett  2021  511:15-25  PubMed ID: 33945837   DOI: 10.1016/j.canlet.2021.04.014
20147  Kariya Y, Oyama M, Suzuki T, Kariya Y.  αvβ3 Integrin induces partial EMT independent of TGF-β signaling.  Commun Biol  2021  4(1):490  PubMed ID: 33883697   DOI: 10.1038/s42003-021-02003-6
14182  Somiya M, Kuroda S.  Real-Time Luminescence Assay for Cytoplasmic Cargo Delivery of Extracellular Vesicles  Anal Chem  2021  93(13):5612-5620  PubMed ID: 33759512   DOI: 10.1021/acs.analchem.1c00339
20150  Takeshita M, Suzuki K, Nakazawa M, Kamata H, Ishii M, Oyamada Y, Oshima H, Takeuchi T.  Antigen-driven autoantibody production in lungs of interstitial lung disease with autoimmune disease.  J Autoimmun  2021  121:102661  PubMed ID: 34034155   DOI: 10.1016/j.jaut.2021.102661
20155  Sahoo PR, Kowada T, Mizukami S.  Long-Term Mg2+ Imaging in Live Cells with a Targetable Fluorescent Probe.  Methods Mol Biol  2021  2274:237-243  PubMed ID: 34050476   DOI: 10.1007/978-1-0716-1258-3_20
20157  Matsui H, Ito J, Matsui N, Uechi T, Onodera O, Kakita A.  Cytosolic dsDNA of mitochondrial origin induces cytotoxicity and neurodegeneration in cellular and zebrafish models of Parkinson's disease.  Nat Commun  2021  12(1):3101  PubMed ID: 34035300   DOI: 10.1038/s41467-021-23452-x
20158  Osakabe K, Wada N, Murakami E, Miyashita N, Osakabe Y.  Genome editing in mammalian cells using the CRISPR type I-D nuclease.  Nucleic Acids Res  2021    PubMed ID: 34076237   DOI: 10.1093/nar/gkab348
20165  Kobayashi JI, Hirasawa H, Fujimori Y, Nakanishi O, Kamada N, Ikeda T, Yamamoto A, Kanbe H.  Identification of N-acyl-N-indanyl-α-phenylglycinamides as selective TRPM8 antagonists designed to mitigate the risk of adverse effects.  Bioorg Med Chem  2021  30:115903  PubMed ID: 33333445   DOI: 10.1016/j.bmc.2020.115903
14478  Yamanaka D, Shoda M, Matsubara T, Ishibashi KI, Motoi A, Motoi R, Motoi M, Ohno N, Adachi Y.  Open-Label Study of the Influence of Food Containing the Royal Sun Mushroom, Agaricus brasiliensis KA21 (Agaricomycetes), on β-Glucan-Specific Antibody Production in Healthy Human Volunteers  Int J Med Mushrooms  2021  23(2):13-28  PubMed ID: 33639078   DOI: 10.1615/IntJMedMushrooms.2020037471
20199  Tomita T, Kato M, Mishima T, Matsunaga Y, Sanjo H, Ito KI, Minagawa K, Matsui T, Oikawa H, Takahashi S, Takao T, Iwai N, Mino T, Takeuchi O, Maru Y, Hiratsuka S.  Extracellular mRNA transported to the nucleus exerts translation-independent function.  Nat Commun  2021  12(1):3655  PubMed ID: 34135341   DOI: 10.1038/s41467-021-23969-1
20200  Kuwabara S, Tanimoto Y, Okutani M, Jie M, Haseda Y, Kinugasa-Katayama Y, Aoshi T.  Microfluidics sorting enables the isolation of an intact cellular pair complex of CD8+ T cells and antigen-presenting cells in a cognate antigen recognition-dependent manner.  PLoS One  2021  16(6):e0252666  PubMed ID: 34125844   DOI: 10.1371/journal.pone.0252666
20216  Niinae T, Imami K, Sugiyama N, Ishihama Y.  Identification of Endogenous Kinase Substrates by Proximity Labeling Combined with Kinase Perturbation and Phosphorylation Motifs.  Mol Cell Proteomics  2021  100119  PubMed ID: 34186244   DOI: 10.1016/j.mcpro.2021.100119
14782  Uemura K, Sasaki M, Sanaki T, Toba S, Takahashi Y, Orba Y, Hall WW, Maenaka K, Sawa H, Sato A.  MRC5 cells engineered to express ACE2 serve as a model system for the discovery of antivirals targeting SARS-CoV-2  Sci Rep  2021  11(1):5376  PubMed ID: 33686154   DOI: 10.1038/s41598-021-84882-7
14827  iu Y, Soh WT, Kishikawa JI, Hirose M, Nakayama EE, Li S, Sasai M, Suzuki T, Tada A, Arakawa A, Matsuoka S, Akamatsu K, Matsuda M, Ono C, Torii S, Kishida K, Jin H, Nakai W, Arase N, Nakagawa A, Matsumoto M, Nakazaki Y, Shindo Y, Kohyama M, Tomii K, Ohmura K, Ohshima S, Okamoto T, Yamamoto M, Nakagami H, Matsuura Y, Nakagawa A, Kato T, Okada M, Standley DM, Shioda T, Arase H.  An infectivity-enhancing site on the SARS-CoV-2 spike protein targeted by antibodies  Cell   2021  184(13):3452-3466.e18  PubMed ID: 34139176   DOI: 10.1016/j.cell.2021.05.032
20233  Koshizuka T, Kondo H, Kato H, Takahashi K.  Human cytomegalovirus UL42 protein inhibits the degradation of glycoprotein B through inhibition of Nedd4 family ubiquitin E3 ligases.  Microbiol Immunol  2021    PubMed ID: 34260096   DOI: 10.1111/1348-0421.12932
20240  Kaku T, Sugiura K, Entani T, Osabe K, Nagai T.  Enhanced brightness of bacterial luciferase by bioluminescence resonance energy transfer.  Sci Rep  2021  11(1):14994  PubMed ID: 34294849   DOI: 10.1038/s41598-021-94551-4
14939  Shuji Hinuma, Kazuyo Fujita, Shun’ichi Kuroda  Binding of Nanoparticles Harboring Recombinant Large Surface Protein of Hepatitis B Virus to Scavenger Receptor Class B Type 1  Viruses  2021  13:1334  PubMed ID: 34372540   DOI: 10.3390/v13071334
20244  Yoshioka K, Obara K, Oikawa S, Uemura K, Yamaguchi A, Fujisawa K, Hanazawa H, Fujiwara M, Endoh T, Suzuki T, Regadera MD, Ito D, Ou G, Xu K, Tanaka Y.  Docosahexaenoic acid inhibits U46619- and prostaglandin F2α-induced pig coronary and basilar artery contractions by inhibiting prostanoid TP receptors.  Eur J Pharmacol  2021  174371  PubMed ID: 34329614   DOI: 10.1016/j.ejphar.2021.174371
20272  Ma Y, Yoshida T, Matoba K, Kida K, Shintani R, Piao Y, Jin J, Nishino T, Hanayama R.  Identification of small compounds regulating the secretion of extracellular vesicles via a TIM4-affinity ELISA.  Sci Rep  2021  11(1):13471  PubMed ID: 34188113   DOI: 10.1038/s41598-021-92860-2
15168  Hangai S, Kawamura T, Kimura Y, Chang CY, Hibino S, Yamamoto D, Nakai Y, Tateishi R, Oshima M, Oshima H, Kodama T, Moriya K, Koike K, Yanai H, Taniguchi T.  Orchestration of myeloid-derived suppressor cells in the tumor microenvironment by ubiquitous cellular protein TCTP released by tumor cells  Nat Immunol  2021  22(8):947-957  PubMed ID: 34239121   DOI: 10.1038/s41590-021-00967-5
20282  Nakanishi E, Uemura N, Akiyama H, Kinoshita M, Masanori S, Taruno Y, Yamakado H, Matsuzawa SI, Takeda S, Hirabayashi Y, Takahashi R.  Impact of Gba2 on neuronopathic Gaucher's disease and α-synuclein accumulation in medaka (Oryzias latipes).  Mol Brain  2021  14(1):80  PubMed ID: 33971917   DOI: 10.1186/s13041-021-00790-x
20283  Sakoguchi A, Saito F, Hirayasu K, Shida K, Matsuoka S, Itagaki S, Nakai W, Kohyama M, Suenaga T, Iwanaga S, Horii T, Arase H.  Plasmodium falciparum RIFIN is a novel ligand for inhibitory immune receptor LILRB2.  Biochem Biophys Res Commun  2021  548:167-173  PubMed ID: 33647792   DOI: 10.1016/j.bbrc.2021.02.033
20298  Nagano C, Takaoka Y, Kamei K, Hamada R, Ichikawa D, Tanaka K, Aoto Y, Ishiko S, Rossanti R, Sakakibara N, Okada E, Horinouchi T, Yamamura T, Tsuji Y, Noguchi Y, Ishimori S, Nagase H, Ninchoji T, Iijima K, Nozu K.  Genotype-Phenotype Correlation in WT1 Exon 8 to 9 Missense Variants.  Kidney Int Rep  2021  6(8):2114-2121  PubMed ID: 34386660   DOI: 10.1016/j.ekir.2021.05.009
20322  Fujisawa S, Qiu H, Nozaki S, Chiba S, Katoh Y, Nakayama K.  ARL3 and ARL13B GTPases participate in distinct steps of INPP5E targeting to the ciliary membrane.  Biol Open  2021    PubMed ID: 34447983   DOI: 10.1242/bio.058843
15284  Yoshiko Iizuka, Kinuko Inomata, Risako Nohara, Akimitsu Miyawaki and Yoshifumi Watanabe  Activation of intracellular antioxidant master gene Nrf2 by the extracts of Garcinia subelliptica, Ocimum gratissimum L., and Plectranthus ornatus  International Journal of Herbal Medicine  2021  9(3):54-60   
15524  Fukasawa K, Kadota T, Horie T, Tokumura K, Terada R, Kitaguchi Y, Park G, Ochiai S, Iwahashi S, Okayama Y, Hiraiwa M, Yamada T, Iezaki T, Kaneda K, Yamamoto M, Kitao T, Shirahase H, Hazawa M, Wong RW, Todo T, Hirao A, Hinoi E.  CDK8 maintains stemness and tumorigenicity of glioma stem cells by regulating the c-MYC pathway  Oncogene  2021  40(15):2803-2815  PubMed ID: 33727660   DOI: 10.1038/s41388-021-01745-1
20354  Noguchi T, Nakamura K, Satoda Y, Katoh Y, Nakayama K.  CCRK/CDK20 regulates ciliary retrograde protein trafficking via interacting with BROMI/TBC1D32.  PLoS One  2021  16(10):e0258497  PubMed ID: 34624068   DOI: 10.1371/journal.pone.0258497
20356  Yasumura M, Hagiwara A, Hida Y, Ohtsuka T.  Planar cell polarity protein Vangl2 and its interacting protein Ap2m1 regulate dendritic branching in cortical neurons.  Genes Cells  2021    PubMed ID: 34626136   DOI: 10.1111/gtc.12899
20367  Kariya Y, Oyama M, Kariya Y, Hashimoto Y.  Phosphorylated Osteopontin Secreted from Cancer Cells Induces Cancer Cell Motility.  Biomolecules  2021  11(9)  PubMed ID: 34572536   DOI: 10.3390/biom11091323
20403  Yaguchi A, Oshikawa M, Watanabe G, Hiramatsu H, Uchida N, Hara C, Kaneko N, Sawamoto K, Muraoka T, Ajioka I.  Efficient protein incorporation and release by a jigsaw-shaped self-assembling peptide hydrogel for injured brain regeneration.  Nat Commun  2021  12(1):6623  PubMed ID: 34799548   DOI: 10.1038/s41467-021-26896-3
20440  Kanadome T, Hoshino N, Nagai T, Matsuda T, Yagi T.  Development of FRET-based indicators for visualizing homophilic trans interaction of a clustered protocadherin.  Sci Rep  2021  11(1):22237  PubMed ID: 34782670   DOI: 10.1038/s41598-021-01481-2
15879  Uemura K, Nobori H, Sato A, Sanaki T, Toba S, Sasaki M, Murai A, Saito-Tarashima N, Minakawa N, Orba Y, Kariwa H, Hall WW, Sawa H, Matsuda A, Maenaka K.  5-Hydroxymethyltubercidin exhibits potent antiviral activity against flaviviruses and coronaviruses, including SARS-CoV-2  iScience  2021  24(10):103120  PubMed ID: 34541466   DOI: 10.1016/j.isci.2021.103120
15898  Yafei Liu, Noriko Arase, Jun-ichi Kishikawa, Mika Hirose, Songling Li, Asa Tada, Sumiko Matsuoka, Akemi Arakawa, Kanako Akamatsu, Chikako Ono, Hui Jin, Kazuki Kishida, Wataru Nakai, Masako Kohyama, Atsushi Nakagawa, Yoshiaki Yamagishi, Hironori Nakagami, Atsushi Kumanogoh, Yoshiharu Matsuura, Daron M. Standley, Takayuki Kato, Masato Okada, Manabu Fujimoto, Hisashi Arase  The SARS-CoV-2 Delta variant is poised to acquire complete resistance to wild-type spike vaccines  bioRxiv  2021      DOI: 10.1101/2021.08.22.457114
20490  Ito F, Kato K, Yanatori I, Murohara T, Toyokuni S.  Ferroptosis-dependent extracellular vesicles from macrophage contribute to asbestos-induced mesothelial carcinogenesis through loading ferritin.  Redox Biol  2021  47:102174  PubMed ID: 34700146   DOI: 10.1016/j.redox.2021.102174
20493  Ishida H, Murakami S, Kamiki H, Matsugo H, Katayama M, Sekine W, Ohira K, Takenaka-Uema A, Horimoto T.  Construction of an Influenza D Virus with an Eight-Segmented Genome.  Viruses  2021  13(11)  PubMed ID: 34834971   DOI: 10.3390/v13112166
16115  Masuo K, Chen R, Yogo A, Sugiyama A, Fukuda A, Masui T, Uemoto S, Seno H, Takaishi S.  SNAIL2 contributes to tumorigenicity and chemotherapy resistance in pancreatic cancer by regulating IGFBP2  Cancer Sci  2021  112(12):4987-4999  PubMed ID: 34628696   DOI: 10.1111/cas.15162
16241  Somiya M, Kuroda S.  Reporter gene assay for membrane fusion of extracellular vesicles  J Extracell Vesicles  2021  10(13):e12171  PubMed ID: 34807503   DOI: 10.1002/jev2.12171
16324  Sheng J, Kohno S, Okada N, Okahashi N, Teranishi K, Matsuda F, Shimizu H, Linn P, Nagatani N, Yamamura M, Harada K, Horike SI, Inoue H, Yano S, Kumar S, Kitajima S, Ajioka I, Takahashi C.  Treatment of Retinoblastoma 1-Intact Hepatocellular Carcinoma With Cyclin-Dependent Kinase 4/6 Inhibitor Combination Therapy  Hepatology  2021  74(4):1971-1993  PubMed ID: 33931882   DOI: 10.1002/hep.31872
16704  PACAP-PAC1 Signaling Regulates Serotonin 2A Receptor Internalization  PACAP-PAC1 Signaling Regulates Serotonin 2A Receptor Internalization  Front Endocrinol (Lausanne)  2021  12:73245  PubMed ID: 34759890   DOI: 10.3389/fendo.2021.732456
16752  Ishii M, Ando J, Yamazaki S, Toyota T, Ohara K, Furukawa Y, Suehara Y, Nakanishi M, Nakashima K, Ohshima K, Nakauchi H, Ando M.  iPSC-Derived Neoantigen-Specific CTL Therapy for Ewing Sarcoma  Cancer Immunol Res  2021  9(10):1175-1186  PubMed ID: 34385178   DOI: 10.1158/2326-6066.CIR-21-0193
16759  Oda K, Matoba Y, Sugiyama M, Sakaguchi T.  Structural Insight into the Interaction of Sendai Virus C Protein with Alix To Stimulate Viral Budding  J Virol  2021  95(19):e0081521  PubMed ID: 34287046   DOI: 10.1128/JVI.00815-21
16762  Wang W, Zhu Y, Sun Z, Jin C, Wang X.  Positive feedback regulation between USP15 and ERK2 inhibits osteoarthritis progression through TGF-β/SMAD2 signaling  Arthritis Res Ther  2021  23(1):84  PubMed ID: 33726807   DOI: 10.1186/s13075-021-02456-4
16764   Pham Tuan Huy   Nguyen Pham Quynh Anh   Tong Thi Hang   Nguyen Hoang Khue Tu   Le Minh Thong   Nguyen Van Thuan   Yen Thi Hai Tran    Home-made in vitro magnetic nanoparticle-based gene delivery system  Science & Technology Development Journal  2021  24:2058-2065    DOI: 10.32508/stdj.v24i3.2573
16766  Ohn J, Been KW, Kim JY, Kim EJ, Park T, Yoon HJ, Ji JS, Okada-Iwabu M, Iwabu M, Yamauchi T, Kim YK, Seok C, Kwon O, Kim KH, Lee HH, Chung JH.  Discovery of a transdermally deliverable pentapeptide for activating AdipoR1 to promote hair growth  EMBO Mol Med  2021  13(10):e13790  PubMed ID: 34486824   DOI: 10.15252/emmm.202013790
17826  Matsubara D, Yoshimoto T, Soda M, Amano Y, Kihara A, Funaki T, Ito T, Sakuma Y, Shibano T, Endo S, Hagiwara K, Ishikawa S, Fukayama M, Murakami Y, Mano H, Niki T.  Reciprocal expression of trefoil factor-1 and thyroid transcription factor-1 in lung adenocarcinomas  Cancer Sci  2020  111(6):2183-2195  PubMed ID: 32237253   DOI: 10.1111/cas.14403
17935  Saito Y, Koya J, Araki M, Kogure Y, Shingaki S, Tabata M, McClure MB, Yoshifuji K, Matsumoto S, Isaka Y, Tanaka H, Kanai T, Miyano S, Shiraishi Y, Okuno Y, Kataoka K.  Landscape and function of multiple mutations within individual oncogenes  Nature  2020  582(7810):95-99  PubMed ID: 32494066   DOI: 10.1038/s41586-020-2175-2
11854  Yamamoto M, Terada Y, Motoyama T, Saito T, Ito K.  Sweet proteins lysozyme and thaumatin are protein-type agonists for the calcium-sensing receptor.  Biochem. Biophys. Res. Commun.  2020  521(1):227-231  PubMed ID: 31635806   DOI: 10.1016/j.bbrc.2019.10.111
6889  Iuchi K, Oya K, Hosoya K, Sasaki K, Sakurada Y, Nakano T, Hisatomi H.  Different morphologies of human embryonic kidney 293T cells in various types of culture dishes.  Cytotechnology  2020  72(1):131-140  PubMed ID: 31865498   DOI: 10.1007/s10616-019-00363-w
9863  Naomi Matsumoto, Reina Matsukawa, Shohei Takahashi, Koshi Kudo, Ge-Hong Sun-Wada, Yoh Wada, Mayumi Nakanishi-Matsui  V-ATPase a3 Isoform Mutations Identified in Osteopetrosis Patients Abolish Its Expression and Disrupt Osteoclast Function  Exp Cell Res  2020  389(2):111901  PubMed ID: 32045577   DOI: 10.1016/j.yexcr.2020.111901
9912  Hiroshi Suzuki, Yuichi Ozaki, Shigeho Ijiri, Koichiro Gen, Yukinori Kazeto  17β-Hydroxysteroid Dehydrogenase Type 12a Responsible for Testicular 11-ketotestosterone Synthesis in the Japanese Eel, Anguilla Japonica  J Steroid Biochem Mol Biol  2020  198:105550  PubMed ID: 31778803   DOI: 10.1016/j.jsbmb.2019.105550
10370  Yusuke Higuchi, Jun-Ichirou Yasunaga, Yu Mitagami, Hirotake Tsukamoto, Kazutaka Nakashima, Koichi Ohshima, Masao Matsuoka  HTLV-1 Induces T Cell Malignancy and Inflammation by Viral Antisense Factor-Mediated Modulation of the Cytokine Signaling  Proc Natl Acad Sci U S A  2020  117(24):13740-13749  PubMed ID: 32471947   DOI: 10.1073/pnas.1922884117
11909  Sakaue T, Hamaguchi M, Aono J, Nakashiro KI, Shikata F, Kawakami N, Oshima Y, Kurata M, Nanba D, Masumoto J, Yamaguchi O, Higashiyama S, Izutani H.  Valve Interstitial Cell-Specific Cyclooxygenase-1 Associated With Calcification of Aortic Valves.  Ann. Thorac. Surg  2020  110(1):40-49  PubMed ID: 31760051   DOI: 10.1016/j.athoracsur.2019.09.085
11927  Yang J, Isaji T, Zhang G, Qi F, Duan C, Fukuda T, Gu J.  EpCAM associates with integrin and regulates cell adhesion in cancer cells.  Biochem. Biophys. Res. Commun.  2020    PubMed ID: 31806375   DOI: 10.1016/j.bbrc.2019.11.152
11944  Qi F, Isaji T, Duan C, Yang J, Wang Y, Fukuda T, Gu J.  ST3GAL3, ST3GAL4, and ST3GAL6 differ in their regulation of biological functions via the specificities for the α2,3-sialylation of target proteins.  FASEB J.  2020    PubMed ID: 31914669   DOI: 10.1096/fj.201901793R
11952  Kimura R, Yoshimaru T, Matsushita Y, Matsuo T, Ono M, Park JH, Sasa M, Miyoshi Y, Nakamura Y, Katagiri T.  The GALNT6‑LGALS3BP axis promotes breast cancer cell growth.  Int. J. Oncol.  2020    PubMed ID: 31894262   DOI: 10.3892/ijo.2019.4941
11958  Hou S, Hang Q, Isaji T, Fukuda T, Gu J.  Identification of the minimal N-glycosylation on integrin α5β1 required for its inhibitory effect on EGFR signaling and cell proliferation.  Biochem. Biophys. Res. Commun.  2020    PubMed ID: 31858971   DOI: 10.1016/j.bbrc.2019.11.188
11990  Duan C, Fukuda T, Isaji T, Qi F, Yang J, Wang Y, Takahashi S, Gu J.  Deficiency of core fucosylation activates cellular signaling dependent on FLT3 expression in a Ba/F3 cell system.  FASEB J.  2020    PubMed ID: 31908039   DOI: 10.1096/fj.201902313RR
12005  Kabayama H, Takeuchi M, Tokushige N, Muramatsu SI, Kabayama M, Fukuda M, Yamada Y, Mikoshiba K.  An ultra-stable cytoplasmic antibody engineered for in vivo applications.  Nat Commun  2020    PubMed ID: 31953402   DOI: 10.1038/s41467-019-13654-9
12015  Yamamoto H, Kon T, Omori Y, Furukawa T.  Functional and Evolutionary Diversification of Otx2 and Crx in Vertebrate Retinal Photoreceptor and Bipolar Cell Development.  Cell Rep  2020    PubMed ID: 31968244   DOI: 10.1016/j.celrep.2019.12.072
12027  Momoi Y, Nishikimi A, Du G, Kataoka T, Katagiri K.  Phosphatidic acid regulates subcellular distribution of RA-GEFs critical for chemokine-dependent migration.  Biochem. Biophys. Res. Commun.  2020    PubMed ID: 31996307   DOI: 10.1016/j.bbrc.2020.01.080
12028  Iuchi K, Tasaki Y, Shirai S, Hisatomi H.  Upregulation of nuclear factor (erythroid-derived 2)-like 2 protein level in the human colorectal adenocarcinoma cell line DLD-1 by a heterocyclic organobismuth(III) compound: Effect of organobismuth(III) compound on NRF2 signaling.  Biomed. Pharmacother.  2020    PubMed ID: 32004978   DOI: 10.1016/j.biopha.2020.109928
12086  Honda A, Chigwechokha PK, Takase R, Hayasaka O, Fujimura K, Kotani T, Komatsu M, Shiozaki K.  Novel Nile tilapia Neu1 sialidases: Molecular cloning and biochemical characterization of the sialidases Neu1a and Neu1b.  Gene  2020    PubMed ID: 32184168   DOI: 10.1016/j.gene.2020.144538
12096  Funakoshi-Tago M, Yu S, Kushida A, Takeuchi K, Tamura H.  Kampo medicines, Rokumigan, Hachimijiogan, and Goshajinkigan, significantly inhibit glucagon-induced CREB activation.  Heliyon  2020    PubMed ID: 32215330   DOI: 10.1016/j.heliyon.2020.e03598
12129  Mutai H, Wasano K, Momozawa Y, Kamatani Y, Miya F, Masuda S, Morimoto N, Nara K, Takahashi S, Tsunoda T, Homma K, Kubo M, Matsunaga T.  Variants encoding a restricted carboxy-terminal domain of SLC12A2 cause hereditary hearing loss in humans.  PLoS Genet.  2020    PubMed ID: 32294086   DOI: 10.1371/journal.pgen.1008643
12364  Liu X, Tajima N, Taniguchi M, Kato N.  The enantiomer pair of 24S- and 24R-hydroxycholesterol differentially alter activity of large-conductance Ca 2+ -dependent K + (slo1 BK) channel  Chirality  2020  32(2):223-230  PubMed ID: 31756018   DOI: 10.1002/chir.23157
13019  Matsuzaki M, Mandai M, Yamanari M, Totani K, Nishida M, Sugita S, Maeda T, Koide N, Takagi S, Hirami Y, Miyamoto N, Sugiyama S, Takahashi M, Kurimoto Y.  Polarization-sensitive optical coherence tomography for estimating relative melanin content of autologous induced stem-cell derived retinal pigment epithelium.  Sci Rep  2020    PubMed ID: 32376945   DOI: 10.1038/s41598-020-64601-4
13020  Koshizuka T, Inoue N.  Activation of c-Jun by human cytomegalovirus UL42 through JNK activation.  PLoS One  2020    PubMed ID: 32369499   DOI: 10.1371/journal.pone.0232635
13024  Kanoh H, Nitta T, Go S, Inamori KI, Veillon L, Nihei W, Fujii M, Kabayama K, Shimoyama A, Fukase K, Ohto U, Shimizu T, Watanabe T, Shindo H, Aoki S, Sato K, Nagasaki M, Yatomi Y, Komura N, Ando H, Ishida H, Kiso M, Natori Y, Yoshimura Y, Zonca A, Cattaneo A, Letizia M, Ciampa M, Mauri L, Prinetti A, Sonnino S, Suzuki A, Inokuchi JI.  Homeostatic and pathogenic roles of GM3 ganglioside molecular species in TLR4 signaling in obesity.  EMBO J  2020    PubMed ID: 32378734   DOI: 10.15252/embj.2019101732
13028  Kido K, Yamanaka S, Nakano S, Motani K, Shinohara S, Nozawa A, Kosako H, Ito S, Sawasaki T.  AirID, a novel proximity biotinylation enzyme, for analysis of protein-protein interactions.  Elife  2020    PubMed ID: 32391793   DOI: 10.7554/eLife.54983
13034  Bajkowska K, Sumardika IW, Tomonobu N, Chen Y, Yamamoto KI, Kinoshita R, Murata H, Gede Yoni Komalasari NL, Jiang F, Yamauchi A, Winarsa Ruma IM, Kasano-Camones CI, Inoue Y, Sakaguchi M.  Neuroplastinβ-mediated upregulation of solute carrier family 22 member 18 antisense (SLC22A18AS) plays a crucial role in the epithelial-mesenchymal transition, leading to lung cancer cells' enhanced motility.  Biochem Biophys Rep  2020    PubMed ID: 32490214   DOI: 10.1016/j.bbrep.2020.100768
13044  Park M, Miyoshi C, Fujiyama T, Kakizaki M, Ikkyu A, Honda T, Choi J, Asano F, Mizuno S, Takahashi S, Yanagisawa M, Funato H.  Loss of the conserved PKA sites of SIK1 and SIK2 increases sleep need.  Sci Rep  2020    PubMed ID: 32457359   DOI: 10.1038/s41598-020-65647-0
13074  Horinouchi T, Yamamura T, Minamikawa S, Nagano C, Sakakibara N, Nakanishi K, Shima Y, Morisada N, Ishiko S, Aoto Y, Nagase H, Takeda H, Rossanti R, Ishimori S, Kaito H, Matsuo M, Iijima K, Nozu K.  Pathogenic evaluation of synonymous COL4A5 variants in X-linked Alport syndrome using a minigene assay.  Mol Genet Genomic Med  2020    PubMed ID: 32543079   DOI: 10.1002/mgg3.1342
13080  Ito F, Yanatori I, Maeda Y, Nimura K, Ito S, Hirayama T, Nagasawa H, Kohyama N, Okazaki Y, Akatsuka S, Toyokuni S.  Asbestos conceives Fe(II)-dependent mutagenic stromal milieu through ceaseless macrophage ferroptosis and β-catenin induction in mesothelium.  Redox Biol  2020    PubMed ID: 32863225   DOI: 10.1016/j.redox.2020.101616
13164  Yamashita J, Takeuchi A, Hosono K, Fleming T, Nagahama Y, Okubo K.  Male-predominant galanin mediates androgen-dependent aggressive chases in medaka.  Elife  2020    PubMed ID: 32783809   DOI: 10.7554/eLife.59470
13182  Ishibashi R, Abe K, Ido N, Kitano S, Miyachi H, Toyoshima F.  Genome editing with the donor plasmid equipped with synthetic crRNA-target sequence.  Sci Rep  2020    PubMed ID: 32839482   DOI: 10.1038/s41598-020-70804-6
13186  Huetter J, Gritzan U, Gutcher I, Doecke WD, Luetke-Eversloh MV, Golfier S, Roider HG, Frisk AL, Hunter J, Pow A, Drake A, Levine Z, Levy O, Azulay M, Barbiro I, Cojocaru G, Vaknin I, Kreft B, Roese L.  Characterization of BAY 1905254, an Immune Checkpoint Inhibitor Targeting the Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2).  Cancer Immunol Res  2020    PubMed ID: 32312711   DOI: 10.1158/2326-6066.CIR-19-0321
13199  Kakizawa S, Kishimoto Y, Yamamoto S, Onga K, Yasuda K, Miyamoto Y, Watanabe M, Sakai R, Mori N.  Functional maintenance of calcium store by ShcB adaptor protein in cerebellar Purkinje cells.  Sci Rep  2020    PubMed ID: 32879382   DOI: 10.1038/s41598-020-71414-y
13200  Ago Y, Otsuka H, Sasai H, Abdelkreem E, Nakama M, Aoyama Y, Matsumoto H, Fujiki R, Ohara O, Akiyama K, Fukui K, Watanabe Y, Nakajima Y, Ohnishi H, Ito T, Fukao T.  Japanese patients with mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase deficiency: In vitro functional analysis of five novel HMGCS2 mutations.  Exp Ther Med  2020    PubMed ID: 32952630   DOI: 10.3892/etm.2020.9166
13204  Kinoshita N, Huang AJY, McHugh TJ, Miyawaki A, Shimogori T.  Diffusible GRAPHIC to visualize morphology of cells after specific cell-cell contact.  Sci Rep  2020    PubMed ID: 32879377   DOI: 10.1038/s41598-020-71474-0
13212  Kitao T, Taguchi K, Seto S, Arasaki K, Ando H, Nagai H, Kubori T.  Legionella Manipulates Non-canonical SNARE Pairing Using a Bacterial Deubiquitinase.  Cell Rep  2020    PubMed ID: 32905772   DOI: 10.1016/j.celrep.2020.108107
13276  Arai Y, Kawashita N, Elgendy EM, Ibrahim MS, Daidoji T, Ono T, Takagi T, Nakaya T, Matsumoto K, Watanabe Y.  PA Mutations Inherited during Viral Evolution Act Cooperatively To Increase Replication of Contemporary H5N1 Influenza Virus with an Expanded Host Range.  J Virol  2020    PubMed ID: 33028722   DOI: 10.1128/JVI.01582-20
13293  Okamura M, Shizu R, Abe T, Kodama S, Hosaka T, Sasaki T, Yoshinari K.  PXR Functionally Interacts with NF-κB and AP-1 to Downregulate the Inflammation-Induced Expression of Chemokine CXCL2 in Mice.  Cells  2020    PubMed ID: 33076328   DOI: 10.3390/cells9102296
13321  Kato M, Onoyama I, Kawakami M, Yoshida S, Kawamura K, Kodama K, Hori E, Cui L, Matsumura Y, Yagi H, Asanoma K, Yahata H, Itakura A, Takeda S, Kato K.  Downregulation of 5-hydroxymethylcytosine is associated with the progression of cervical intraepithelial neoplasia.  PLoS One  2020    PubMed ID: 33141854   DOI: 10.1371/journal.pone.0241482
13327  Yamazaki T, Takahashi C, Taniguchi Y, Narukawa M, Misaka T, Ano Y.  Bitter taste receptor activation by hop-derived bitter components induces gastrointestinal hormone production in enteroendocrine cells.  Biochem Biophys Res Commun  2020    PubMed ID: 33160623   DOI: 10.1016/j.bbrc.2020.10.099
13330  Osakabe K, Wada N, Miyaji T, Murakami E, Marui K, Ueta R, Hashimoto R, Abe-Hara C, Kong B, Yano K, Osakabe Y.  Genome editing in plants using CRISPR type I-D nuclease.  Commun Biol  2020  3(1):648  PubMed ID: 33159140   DOI: 10.1038/s42003-020-01366-6
13490  Shoji S, Hanada K, Takahashi M, Watanabe K, Yonemochi M, Tomabechi Y, Shirouzu M.  The NF-κB regulator IκBβ exhibits different molecular interactivity and phosphorylation status from IκBα in an IKK2-catalysed reaction  FEBS Lett  2020  594(10):1532-1549  PubMed ID: 32017069   DOI: 10.1002/1873-3468.13752
13554  Tohama T, Sakari M, Tsukahara T.  Development of a Single Construct System for Site-Directed RNA Editing Using MS2-ADAR  Int J Mol Sci  2020  ;21(14):4943  PubMed ID: 32668759   DOI: 10.3390/ijms21144943
13567  Harada M, Nghia VT, Nakao A, Tanigaki R, Fukuoka N, Nishida A, Kataoka T.  Eomesodermin promotes interaction of RelA and NFATc2 with the Ifng promoter and multiple conserved noncoding sequences across the Ifng locus in mouse lymphoma BW5147 cells  Immunol Lett  2020  225:33-43  PubMed ID: 32554052   DOI: 10.1016/j.imlet.2020.06.008
13570  Suzuki T, Morimoto N, Akaike A, Osakada F.  Multiplex Neural Circuit Tracing With G-Deleted Rabies Viral Vectors  Front Neural Circuits  2020  13:77  PubMed ID: 31998081   DOI: 10.3389/fncir.2019.00077
13575  Suzuki F, Okuno M, Tanaka T, Sanuki R.  Overexpression of neural miRNAs miR-9/9* and miR-124 suppresses differentiation to Müller glia and promotes differentiation to neurons in mouse retina in vivo  Genes Cells  2020  25(11):741-752  PubMed ID: 32979863   DOI: 10.1111/gtc.12809
13577  Shimada K, Kobayashi N, Oka N, Takahashi M, Kondo K.  Cooperative activation of the human herpesvirus 6B U79/80 early gene promoter by immediate-early proteins IE1B and IE2B  Microbiol Immunol  2020  64(11):747-761  PubMed ID: 32910457   DOI: 10.1111/1348-0421.12844
13599  Murakami S, Mochimaru Y, Musha S, Kojima R, Deai M, Mogi C, Sato K, Okajima F, Tomura H.  Species-Dependent Enhancement of Ovarian Cancer G Protein-Coupled Receptor 1 Activation by Ogerin  Zoolog Sci  2020  37(2):103-108  PubMed ID: 32282140   DOI: 10.2108/zs190106
13606  Wardhani BW, Puteri MU, Watanabe Y, Louisa M, Setiabudy R, Kato M.  TGF-β-Induced TMEPAI Attenuates the Response of Triple-Negative Breast Cancer Cells to Doxorubicin and Paclitaxel  J Exp Pharmacol  2020  12:17-26  PubMed ID: 32158279   DOI: 10.2147/JEP.S235233
13629  Yamamoto M, Terada Y, Motoyama T, Shibata M, Saito T, Ito K.  N-terminal [Glu] 3 moiety of γ-glutamyl peptides contributes largely to the activation of human calcium-sensing receptor, a kokumi receptor  Biosci Biotechnol Biochem  2020  84(7):1497-1500  PubMed ID: 32202205   DOI: 10.1080/09168451.2020.1743169
13772  Sawada Y, Kikugawa T, Iio H, Sakakibara I, Yoshida S, Ikedo A, Yanagihara Y, Saeki N, Győrffy B, Kishida T, Okubo Y, Nakamura Y, Miyagi Y, Saika T, Imai Y.  GPRC5A facilitates cell proliferation through cell cycle regulation and correlates with bone metastasis in prostate cancer  Int J Cancer  2020  146(5):1369-1382  PubMed ID: 31276604   DOI: 10.1002/ijc.32554
13917  Tamai K, Nakamura-Shima M, Shibuya-Takahashi R, Kanno SI, Yasui A, Mochizuki M, Iwai W, Wakui Y, Abue M, Yamamoto K, Miura K, Mizuma M, Unno M, Kawamura S, Sato I, Yasuda J, Yamaguchi K,   BEX2 suppresses mitochondrial activity and is required for dormant cancer stem cell maintenance in intrahepatic cholangiocarcinoma  Sci Rep  2020  10(1):21592  PubMed ID: 33299012   DOI: 10.1038/s41598-020-78539-0
14525  Ishida H, Murakami S, Kamiki H, Matsugo H, Takenaka-Uema A, Horimoto T.  Establishment of a Reverse Genetics System for Influenza D Virus  J Virol  2020  94(10):e01767-19  PubMed ID: 32102883   DOI: 10.1128/JVI.01767-19
14805  Yokomizo-Nakano T, Kubota S, Bai J, Hamashima A, Morii M, Sun Y, Katagiri S, Iimori M, Kanai A, Tanaka D, Oshima M, Harada Y, Ohyashiki K, Iwama A, Harada H, Osato M, Sashida G.  Overexpression of RUNX3 Represses RUNX1 to Drive Transformation of Myelodysplastic Syndrome  Cancer Res  2020  80(12):2523-2536  PubMed ID: 32341038   DOI: 10.1158/0008-5472.CAN-19-3167
14840  Ueo A, Kubota M, Shirogane Y, Ohno S, Hashiguchi T, Yanagi Y.  Lysosome-Associated Membrane Proteins Support the Furin-Mediated Processing of the Mumps Virus Fusion Protein  J Virol   2020  94(12):e00050-20  PubMed ID: 32295904   DOI: 10.1128/JVI.00050-20
14855  Effective RNA Knockdown Using CRISPR-Cas13a and Molecular Targeting of the EML4-ALK Transcript in H3122 Lung Cancer Cells  Effective RNA Knockdown Using CRISPR-Cas13a and Molecular Targeting of the EML4-ALK Transcript in H3122 Lung Cancer Cells  Int J Mol Sci   2020  21(23):8904  PubMed ID: 33255340   DOI: 10.3390/ijms21238904
14862  Mizutani T, Ohba Y, Mizuta S, Yasuda J, Urata S.  An Antiviral Drug Screening Platform with a FRET Biosensor for Measurement of Arenavirus Z Assembly  Cell Struct Funct   2020  45(2):155-163  PubMed ID: 33191384   DOI: 10.1247/csf.20030
14868  Toda K, Tsukayama I, Nagasaki Y, Konoike Y, Tamenobu A, Ganeko N, Ito H, Kawakami Y, Takahashi Y, Miki Y, Yamamoto K, Murakami M, Suzuki-Yamamoto T.  Red-kerneled rice proanthocyanidin inhibits arachidonate 5-lipoxygenase and decreases psoriasis-like skin inflammation  Arch Biochem Biophys  2020  689:108307  PubMed ID: 32112739   DOI: 10.1016/j.abb.2020.108307
16634  Adachi K, Yamada T, Ishizuka H, Oki M, Tsunogae S, Shimada N, Chiba O, Orihara T, Hidaka M, Hirokawa T, Odagi M, Konoki K, Yotsu-Yamashita M, Nagasawa K.  Synthesis of C12-Keto Saxitoxin Derivatives with Unusual Inhibitory Activity Against Voltage-Gated Sodium Channels  Chemistry  2020  26(9):2025-2033  PubMed ID: 31769085   DOI: 10.1002/chem.201904184
11244  Zhang G, Isaji T, Xu Z, Lu X, Fukuda T, Gu J.  N-acetylglucosaminyltransferase-I as a novel regulator of epithelial-mesenchymal transition.  FASEB J.  2019    PubMed ID: 30307765   DOI: 10.1096/fj.201801478R
11273  Mizuno M, Miki R, Moriyama Y, Ushida T, Imai K, Niimi K, Nakano T, Tsuda H, Sumigama S, Yamamoto E, Senga T, Iwase A, Kikkawa F, Kotani T.  The role of E2F8 in the human placenta.  Mol Med Rep  2019    PubMed ID: 30387815   DOI: 10.3892/mmr.2018.9617
11319  Nitta T, Kanoh H, Inamori KI, Suzuki A, Takahashi T, Inokuchi JI.  Globo-series glycosphingolipids enhance Toll-like receptor 4-mediated inflammation and play a pathophysiological role in diabetic nephropathy.  Glycobiology  2019    PubMed ID: 30476082   DOI: 10.1093/glycob/cwy105
11315  Arai Y, Ibrahim MS, Elgendy EM, Daidoji T, Ono T, Suzuki Y, Nakaya T, Matsumoto K, Watanabe Y.  Genetic Compatibility of Reassortants between Avian H5N1 and H9N2 Influenza Viruses with Higher Pathogenicity in Mammals.  J. Virol.  2019    PubMed ID: 30463961   DOI: 10.1128/JVI.01969-18
11327  Ishikawa K, Hara T, Kato K, Shimomura T, Omori K.  Involvement of natriuretic peptide system in C2C12 myocytes.  Mol. Cell. Biochem.  2019  56(1-2):15-27  PubMed ID: 30519782   DOI: 10.1007/s11010-018-3486-6
11355  Xu Z, Isaji T, Fukuda T, Wang Y, Gu J.  O-GlcNAcylation regulates integrin-mediated cell adhesion and migration via formation of focal adhesion complexes.  J. Biol. Chem.  2019    PubMed ID: 30587575   DOI: 10.1074/jbc.RA118.005923
11368  Suzuki N, Hirano K, Ogino H, Ochi H.  Arid3a regulates nephric tubule regeneration via evolutionarily conserved regeneration signal-response enhancers.  Elife  2019    PubMed ID: 30616715   DOI: 10.7554/eLife.43186
11404  Kataoka K, Miyoshi H, Sakata S, Dobashi A, Couronné L, Kogure Y, Sato Y, Nishida K, Gion Y, Shiraishi Y, Tanaka H, Chiba K, Watatani Y, Kakiuchi N, Shiozawa Y, Yoshizato T, Yoshida K, Makishima H, Sanada M, Onozawa M, Teshima T, Yoshiki Y, Ishida T, Suzuki K, Shimada K, Tomita A, Kato M, Ota Y, Izutsu K, Demachi-Okamura A, Akatsuka Y, Miyano S, Yoshino T, Gaulard P, Hermine O, Takeuchi K, Ohshima K, Ogawa S.  Frequent structural variations involving programmed death ligands in Epstein-Barr virus-associated lymphomas.  Leukemia  2019    PubMed ID: 30683910   DOI: 10.1038/s41375-019-0380-5
11416  Matsumoto N, Nakanishi-Matsui M.  Proton pumping V-ATPase inhibitor bafilomycin A1 affects Rab7 lysosomal localization and abolishes anterograde trafficking of osteoclast secretory lysosomes.  Biochem. Biophys. Res. Commun.  2019    PubMed ID: 30717974   DOI: 10.1016/j.bbrc.2019.01.118
11418  Shimizu Y, Kohyama M, Yorifuji H, Jin H, Arase N, Suenaga T, Arase H.  FcγRIIIA-mediated activation of NK cells by IgG heavy chain complexed with MHC class II molecules.  Int. Immunol.  2019    PubMed ID: 30721990   DOI: 10.1093/intimm/dxz010
11430  Ishibashi D, Homma T, Nakagaki T, Fuse T, Sano K, Satoh K, Mori T, Atarashi R, Nishida N.  Type I interferon protects neurons from prions in in vivo models.  Brain  2019    PubMed ID: 30753318   DOI: 10.1093/brain/awz016
11475  Yorifuji H, Arase N, Kohyama M, Hirano T, Suenaga T, Kumanogoh A, Arase H.  Transport of cellular misfolded proteins to the cell surface by HLA-B27 free heavy chain.  Biochem. Biophys. Res. Commun.  2019    PubMed ID: 30850159   DOI: 10.1016/j.bbrc.2019.02.120
11465  Sarkar B, Nishikata I, Nakahata S, Ichikawa T, Shiraga T, Saha HR, Fujii M, Tanaka Y, Shimoda K, Morishita K.  Degradation of p47 by autophagy contributes to CADM1 overexpression in ATLL cells through the activation of NF-κB.  Sci Rep  2019    PubMed ID: 30837480   DOI: 10.1038/s41598-019-39424-7
11490  Chen Y, Sumardika IW, Tomonobu N, Winarsa Ruma IM, Kinoshita R, Kondo E, Inoue Y, Sato H, Yamauchi A, Murata H, Yamamoto KI, Tomida S, Shien K, Yamamoto H, Soh J, Liu M, Futami J, Sasai K, Katayama H, Kubo M, Putranto EW, Hibino T, Sun B, Nishibori M, Toyooka S, Sakaguchi M.  Melanoma cell adhesion molecule is the driving force behind the dissemination of melanoma upon S100A8/A9 binding in the original skin lesion.  Cancer Lett.  2019    PubMed ID: 30904617   DOI: 10.1016/j.canlet.2019.03.023
5345  Yamaguchi S, Tanimoto A, Iwasa S, Otsuguro KI.  TRPM4 and TRPM5 Channels Share Crucial Amino Acid Residues for Ca2+ Sensitivity but Not Significance of PI(4,5)P2.  Int J Mol Sci  2019  20(8):2012  PubMed ID: 31022885   DOI: 10.3390/ijms20082012
6833  Yokoyama T, Machida K, Iwasaki W, Shigeta T, Nishimoto M, Takahashi M, Sakamoto A, Yonemochi M, Harada Y, Shigematsu H, Shirouzu M, Tadakuma H, Imataka H, Ito T.  HCV IRES Captures an Actively Translating 80S Ribosome.  Mol Cell  2019  74(6):1205-1214  PubMed ID: 31080011   DOI: 10.1016/j.molcel.2019.04.022
11500  Mizuta H, Kuga K, Suzuki T, Niwa Y, Dohmae N, Simizu S.  C‑mannosylation of R‑spondin2 activates Wnt/β‑catenin signaling and migration activity in human tumor cells.  Int. J. Oncol.  2019    PubMed ID: 30942431   DOI: 10.3892/ijo.2019.4767
11520  Liu YY, Tanikawa C, Ueda K, Matsuda K.  INKA2, a novel p53 target that interacts with the serine/threonine kinase PAK4.  Int. J. Oncol.  2019    PubMed ID: 31081062   DOI: 10.3892/ijo.2019.4786
11554  Matsubara H, Tanaka R, Tateishi T, Yoshida H, Yamaguchi M, Kataoka T.  The human Bcl-2 family member Bcl-rambo and voltage-dependent anion channels manifest a genetic interaction in Drosophila and cooperatively promote the activation of effector caspases in human cultured cells.  Exp. Cell Res.  2019    PubMed ID: 31102594   DOI: 10.1016/j.yexcr.2019.05.015
11555  Chen Y, Sumardika IW, Tomonobu N, Kinoshita R, Inoue Y, Iioka H, Mitsui Y, Saito K, Ruma IMW, Sato H, Yamauchi A, Murata H, Yamamoto KI, Tomida S, Shien K, Yamamoto H, Soh J, Futami J, Kubo M, Putranto EW, Murakami T, Liu M, Hibino T, Nishibori M, Kondo E, Toyooka S, Sakaguchi M.  Critical role of the MCAM-ETV4 axis triggered by extracellular S100A8/A9 in breast cancer aggressiveness.  Neoplasia  2019    PubMed ID: 31100639   DOI: 10.1016/j.neo.2019.04.006
11580  Tanaka J, Mabuchi Y, Hata K, Yasuhara R, Takamatsu K, Kujiraoka S, Yukimori A, Takakura I, Sumimoto H, Fukada T, Azuma M, Akiyama H, Nishimura R, Shimane T, Mishima K.  Sox9 regulates the luminal stem/progenitor cell properties of salivary glands.  Exp. Cell Res.  2019    PubMed ID: 31153924   DOI: 10.1016/j.yexcr.2019.05.030
11621  Arai Y, Kawashita N, Ibrahim MS, Elgendy EM, Daidoji T, Ono T, Takagi T, Nakaya T, Matsumoto K, Watanabe Y.  PB2 mutations arising during H9N2 influenza evolution in the Middle East confer enhanced replication and growth in mammals.  PLoS Pathog.  2019    PubMed ID: 31265471   DOI: 10.1371/journal.ppat.1007919
11624  Furuse Y, Chaimongkol N, Okamoto M, Oshitani H.  Evolutionary and Functional Diversity of the 5' Untranslated Region of Enterovirus D68: Increased Activity of the Internal Ribosome Entry Site of Viral Strains during the 2010s.  Viruses  2019    PubMed ID: 31288421   DOI: 10.3390/v11070626
11643  Ishii J, Suzuki A, Kimura T, Tateyama M, Tanaka T, Yazawa T, Arimasu Y, Chen IS, Aoyama K, Kubo Y, Saitoh S, Mizuno H, Kamma H.  Congenital goitrous hypothyroidism is caused by dysfunction of the iodide transporter SLC26A7.  Commun Biol  2019    PubMed ID: 31372509   DOI: 10.1038/s42003-019-0503-6
11647  Wong JH, Shigemizu D, Yoshii Y, Akiyama S, Tanaka A, Nakagawa H, Narumiya S, Fujimoto A.  Identification of intermediate-sized deletions and inference of their impact on gene expression in a human population.  Genome Med  2019    PubMed ID: 31340865   DOI: 10.1186/s13073-019-0656-4
11716  Makino Y, Jensen NH, Yokota N, Rossner MJ, Akiyama H, Shirahige K, Okada Y.  Single cell RNA-sequencing identified Dec2 as a suppressive factor for spermatogonial differentiation by inhibiting Sohlh1 expression.  Sci Rep  2019    PubMed ID: 30988352   DOI: 10.1038/s41598-019-42578-z
11720  Yamanashi T, Maki M, Kojima K, Shibukawa A, Tsukamoto T, Chowdhury S, Yamanaka A, Takagi S, Sudo Y.  Quantitation of the neural silencing activity of anion channelrhodopsins in Caenorhabditis elegans and their applicability for long-term illumination.  Sci Rep  2019    PubMed ID: 31133660   DOI: 10.1038/s41598-019-44308-x
11766  Su Y, Nichuguti N, Kuroki-Kami A, Fujiwara H.  Sequence-specific retrotransposition of 28S rDNA-specific LINE R2Ol in human cells.  RNA  2019    PubMed ID: 31434792   DOI: 10.1261/rna.072512.119
11845  Kamiki H, Matsugo H, Ishida H, Kobayashi-Kitamura T, Sekine W, Takenaka-Uema A, Murakami S, Horimoto T.  Adaptation of H3N2 canine influenza virus to feline cell culture.  PLoS ONE  2019    PubMed ID: 31600274   DOI: 10.1371/journal.pone.0223507
11855  Morita A, Aoshima K, Gulay KCM, Onishi S, Shibata Y, Yasui H, Kobayashi A, Kimura T.  High drug efflux pump capacity and low DNA damage response induce doxorubicin resistance in canine hemangiosarcoma cell lines.  Res. Vet. Sci.  2019    PubMed ID: 31648115   DOI: 10.1016/j.rvsc.2019.09.011
6886  Musha S, Nagayama S, Murakami S, Kojima R, Deai M, Sato K, Okajima F, Ueharu H, Tomura H.  Protons Differentially Activate TDAG8 Homologs from Various Species.  Zoolog Sci  2019  36(2):105-111  PubMed ID: 31120644   DOI: 10.2108/zs180128
6931  Nakanishi M, Hino M, Yoshimura M, Amakura Y, Nomoto H.  Identification of sinensetin and nobiletin as major antitrypanosomal factors in a citrus cultivar.  Exp Parasitol  2019  200:24-29  PubMed ID: 30898543   DOI: 10.1016/j.exppara.2019.03.008
9468  Kazuyo Fujita, Masaharu Somiya, Shun'ichi Kuroda, Shuji Hinuma  Induction of Lipid Droplets in Non-Macrophage Cells as Well as Macrophages by Liposomes and Exosomes  Biochem Biophys Res Commun  2019  510(1):184-190  PubMed ID: 30678809   DOI: 10.1016/j.bbrc.2019.01.078
11700  Uchibori R, Teruya T, Ido H, Ohmine K, Sehara Y, Urabe M, Mizukami H, Mineno J, Ozawa K.  Functional Analysis of an Inducible Promoter Driven by Activation Signals from a Chimeric Antigen Receptor  Mol Ther Oncolytics  2019  2:16-25  PubMed ID: 30662937   DOI: 10.1016/j.omto.2018.11.003
12285  Arisa Mitani, Takeshi Kobayashi, Yasuhito Hayashi, Natsuki Matsushita, Sachi Matsushita, Saori Nakao, Naoko Takahira, Atsushi Shiraishi, Yuichi Ohashi   Characterization of doxycycline-dependent inducible Simian Virus 40 large T antigen immortalized human conjunctival epithelial cell line  PLoS One  2019  14(9):e0222454  PubMed ID: 31509592   DOI: 10.1371/journal.pone.0222454
12299  Nobuyoshi Tajima, Liu Xiaoyan, Makoto Taniguchi, Nobuo Kato  24S-hydroxycholesterol alters activity of large-conductance Ca 2+-dependent K + (slo1 BK) channel through intercalation into plasma membrane  Biochim Biophys Acta Mol Cell Biol Lipids  2019  1864(10):1525-1535  PubMed ID: 31136842   DOI: 10.1016/j.bbalip.2019.05.010
12354  Shimizu K, Yamasaki S, Sakurai M, Yumoto N, Ikeda M, Mishima-Tsumagari C, Kukimoto-Niino M, Watanabe T, Kawamura M, Shirouzu M, Fujii SI.  Granzyme A Stimulates pDCs to Promote Adaptive Immunity via Induction of Type I IFN  Front Immunol  2019  10:1450  PubMed ID: 31293597   DOI: 10.3389/fimmu.2019.01450
12362  Takahashi Y, Takahashi H, Stern PL, Kirita T, Tsuboi A.  Expression of Oncofetal Antigen 5T4 in Murine Taste Papillae  Front Cell Neurosci  2019  13:343  PubMed ID: 31417363   DOI: 10.3389/fncel.2019.00343
12363  Ichikawa T, Nakahata S, Fujii M, Iha H, Shimoda K, Morishita K.  The regulation of NDRG2 expression during ATLL development after HTLV-1 infection  Biochim Biophys Acta Mol Basis Dis  2019  1865(10):2633-2646  PubMed ID: 31295529   DOI: 10.1016/j.bbadis.2019.07.001
12365  Okamura M, Shizu R, Hosaka T, Sasaki T, Yoshinari K.  Possible involvement of the competition for the transcriptional coactivator glucocorticoid receptor-interacting protein 1 in the inflammatory signal-dependent suppression of PXR-mediated CYP3A induction in vitro  Drug Metab Pharmacokinet  2019  34(4):272-279  PubMed ID: 31280915   DOI: 10.1016/j.dmpk.2019.04.005
12367  Mitsui Y, Tomonobu N, Watanabe M, Kinoshita R, Sumardika IW, Youyi C, Murata H, Yamamoto KI, Sadahira T, Rodrigo AGH, Takamatsu H, Araki K, Yamauchi A, Yamamura M, Fujiwara H, Inoue Y, Futami J, Saito K, Iioka H, Kondo E, Nishibori M, Toyooka S, Yamamoto Y, Nasu Y, Sakaguchi M.  Upregulation of Mobility in Pancreatic Cancer Cells by Secreted S100A11 Through Activation of Surrounding Fibroblasts  Oncol Res  2019  27(8):945-956.  PubMed ID: 31046874   DOI: 10.3727/096504019X15555408784978
12437  Hara N, Osago H, Hiyoshi M, Kobayashi-Miura M, Tsuchiya M.  Quantitative analysis of the effects of nicotinamide phosphoribosyltransferase induction on the rates of NAD+ synthesis and breakdown in mammalian cells using stable isotope-labeling combined with mass spectrometry  PLoS One  2019  14(3):e0214000  PubMed ID: 30875389   DOI: 10.1371/journal.pone.0214000
12496  Liu Y, Wang Y, Wang F, Pan J, Xu J, Li J, Zhou C, Ding G, Wu Y, Liu X, Sheng J, Huang H.  Mechanism underlying the retarded nuclear translocation of androgen receptor splice variants  Sci China Life Sci  2019  62(2):257-267  PubMed ID: 30267260   DOI: 10.1007/s11427-018-9379-x
12588  Yoh T, Hatano E, Kasai Y, Fuji H, Nishi K, Toriguchi K, Sueoka H, Ohno M, Seo S, Iwaisako K, Taura K, Yamaguchi R, Kurokawa M, Fujimoto J, Kimura T, Uemoto S, Nishi E.  Serum Nardilysin, a Surrogate Marker for Epithelial-Mesenchymal Transition, Predicts Prognosis of Intrahepatic Cholangiocarcinoma after Surgical Resection  Clin Cancer Res  2019  25(2):619-628  PubMed ID: 30352908   DOI: 10.1158/1078-0432.CCR-18-0124
14890  Maishi N, Kikuchi H, Sato M, Nagao-Kitamoto H, Annan DA, Baba S, Hojo T, Yanagiya M, Ohba Y, Ishii G, Masutomi K, Shinohara N, Hida Y, Hida K.  Development of Immortalized Human Tumor Endothelial Cells from Renal Cancer  Int J Mol Sci  2019  20(18):4595  PubMed ID: 31533313   DOI: 10.3390/ijms20184595
17181  Sumardika IW, Chen Y, Tomonobu N, Kinoshita R, Ruma IMW, Sato H, Kondo E, Inoue Y, Yamauchi A, Murata H, Yamamoto KI, Tomida S, Shien K, Yamamoto H, Soh J, Futami J, Putranto EW, Hibino T, Nishibori M, Toyooka S, Sakaguchi M.  Neuroplastin-β mediates S100A8/A9-induced lung cancer disseminative progression  Mol Carcinog  2019  58(6):980-995  PubMed ID: 30720226   DOI: 10.1002/mc.22987
18202  Horigome E, Fujieda M, Handa T, Katayama A, Ito M, Ichihara A, Tanaka D, Gombodorj N, Yoshiyama S, Yamane A, Yamada K, Horiguchi J, Shinozuka K, Oyama T, Nishiyama M, Rokudai S.  Mutant TP53 modulates metastasis of triple negative breast cancer through adenosine A2b receptor signaling  Oncotarget  2018  9(77):34554-34566  PubMed ID: 30349649   DOI: 10.18632/oncotarget.26177
9500  Kanda K, Sakamoto J, Matsumoto Y, Ikuta K, Goto N, Morita Y, Ohno M, Nishi K, Eto K, Kimura Y, Nakanishi Y, Ikegami K, Yoshikawa T, Fukuda A, Kawada K, Sakai Y, Ito A, Yoshida M, Kimura T, Chiba T, Nishi E, Seno H.  Nardilysin controls intestinal tumorigenesis through HDAC1/p53-dependent transcriptional regulation.  JCI Insight  2018  3:  PubMed ID: 29669932   DOI: 10.1172/jci.insight.91316
10788  Koshizuka T, Kobayashi T, Ishioka K, Suzutani T.  Herpesviruses possess conserved proteins for interaction with Nedd4 family ubiquitin E3 ligases.  Sci Rep  2018  8:4447  PubMed ID: 29535361   DOI: 10.1038/s41598-018-22682-2
10808  Mochimaru Y, Negishi J, Murakami S, Musha S, Sato K, Okajima F, Tomura H.  Metals Differentially Activate Ovarian Cancer G Protein-Coupled Receptor 1 in Various Species.  Zool. Sci.  2018  35:109-114  PubMed ID: 29623784   DOI: 10.2108/zs170145
10817  Yamashita W, Takahashi M, Kikkawa T, Gotoh H, Osumi N, Ono K, Nomura T.  Conserved and divergent functions of Pax6 underlie species-specific neurogenic patterns in the developing amniote brain.  Development  2018  145:  PubMed ID: 29661783   DOI: 10.1242/dev.159764
11042  Shigenori Inagaki; Masakazu Agetsuma; Takeharu Nagai  A novel fiber-free technique for brain activity imaging in multiple freely behaving mice  SPIE BiOS  2018      DOI: 10.1117/12.2302396
11080  Wang Y, Cao L, Lee CY, Matsuo T, Wu K, Asher G, Tang L, Saitoh T, Russell J, Klewe-Nebenius D, Wang L, Soya S, Hasegawa E, Cherasse Y, Zhou J, Li Y, Wang T, Zhan X, Miyoshi C, Irukayama Y, Cao J, Meeks JP, Gautron L, Wang Z, Sakurai K, Funato H, Sakurai T, Yanagisawa M, Nagase H, Kobayakawa R, Kobayakawa K, Beutler B, Liu Q.  Large-scale forward genetics screening identifies Trpa1 as a chemosensor for predator odor-evoked innate fear behaviors.  Nat Commun  2018  9(1):2041  PubMed ID: 29795268   DOI: 10.1038/s41467-018-04324-3
11137  Iuchi K, Morisada Y, Yoshino Y, Himuro T, Saito Y, Murakami T, Hisatomi H.  Cold atmospheric-pressure nitrogen plasma induces the production of reactive nitrogen species and cell death by increasing intracellular calcium in HEK293T cells.  Arch. Biochem. Biophys.  2018  654:136-145  PubMed ID: 30026027   DOI: 10.1016/j.abb.2018.07.015
11144  Funakohi-Tago M, Sakata T, Fujiwara S, Sakakura A, Sugai T, Tago K, Tamura H.  Hydroxytyrosol butyrate inhibits 6-OHDA-induced apoptosis through activation of the Nrf2/HO-1 axis in SH-SY5Y cells.  Eur. J. Pharmacol.  2018  834:246-256  PubMed ID: 30053409   DOI: 10.1016/j.ejphar.2018.07.043
11189  Kawaguchi M, Tani T, Hombu R, Ieda N, Nakagawa H.  Development and cellular application of visible-light-controllable HNO releasers based on caged Piloty's acid.  Chem. Commun. (Camb.)  2018  54(73):10371-10374  PubMed ID: 30152479   DOI: 10.1039/c8cc04954h
11205  Shiozawa Y, Malcovati L, Galli A, Sato-Otsubo A, Kataoka K, Sato Y, Watatani Y, Suzuki H, Yoshizato T, Yoshida K, Sanada M, Makishima H, Shiraishi Y, Chiba K, Hellstrom-Lindberg E, Miyano S, Ogawa S, Cazzola M.  Aberrant splicing and defective mRNA production induced by somatic spliceosome mutations in myelodysplasia.  Nat Commun  2018    PubMed ID: 30194306   DOI: 10.1038/s41467-018-06063-x
11222  Ageta H, Ageta-Ishihara N, Hitachi K, Karayel O, Onouchi T, Yamaguchi H, Kahyo T, Hatanaka K, Ikegami K, Yoshioka Y, Nakamura K, Kosaka N, Nakatani M, Uezumi A, Ide T, Tsutsumi Y, Sugimura H, Kinoshita M, Ochiya T, Mann M, Setou M, Tsuchida K.  UBL3 modification influences protein sorting to small extracellular vesicles.  Nat Commun  2018    PubMed ID: 30258067   DOI: 10.1038/s41467-018-06197-y
11233  Aoshima K, Fukui Y, Gulay KCM, Erdemsurakh O, Morita A, Kobayashi A, Kimura T.  Notch2 signal is required for the maintenance of canine hemangiosarcoma cancer stem cell-like cells.  BMC Vet. Res.  2018    PubMed ID: 30285832   DOI: 10.1186/s12917-018-1624-8
11156  Ito S, Kayukawa N, Ueda T, Taniguchi H, Morioka Y, Hongo F, Ukimura O.  MRGBP promotes AR-mediated transactivation of KLK3 and TMPRSS2 via acetylation of histone H2A.Z in prostate cancer cells.  Biochim Biophys Acta Gene Regul Mech  2018    PubMed ID: 30076933   DOI: 10.1016/j.bbagrm.2018.07.014
11112  Niino T, Tago K, Yasuda D, Takahashi K, Mashino T, Tamura H, Funakoshi-Tago M.  A 5-hydroxyoxindole derivative attenuates LPS-induced inflammatory responses by activating the p38-Nrf2 signaling axis.  Biochem. Pharmacol.  2018  155:182-197  PubMed ID: 29940171   DOI: 10.1016/j.bcp.2018.06.021
11217  Matsuura R, Kaji H, Tomioka A, Sato T, Narimatsu H, Moriwaki Y, Misawa H, Imai K, Tsuji S.  Identification of mesothelioma-specific sialylated epitope recognized with monoclonal antibody SKM9-2 in a mucin-like membrane protein HEG1.  Sci Rep  2018    PubMed ID: 30250045   DOI: 10.1038/s41598-018-32534-8
11313  Kamiki H, Matsugo H, Kobayashi T, Ishida H, Takenaka-Uema A, Murakami S, Horimoto T.  A PB1-K577E Mutation in H9N2 Influenza Virus Increases Polymerase Activity and Pathogenicity in Mice.  Viruses  2018    PubMed ID: 30463209   DOI: 10.3390/v10110653
11343  Saeki E, Yasuhira S, Shibazaki M, Tada H, Doita M, Masuda T, Maesawa C.  Involvement of C-terminal truncation mutation of kinesin-5 in resistance to kinesin-5 inhibitor.  PLoS ONE  2018    PubMed ID: 30557316   DOI: 10.1371/journal.pone.0209296
11370  Xu P, Kai C, Kawasaki S, Kobayashi Y, Yamamoto K, Tsujikawa M, Hayashi R, Nishida K.  A New in Vitro Model of GDLD by Knocking Out TACSTD2 and Its Paralogous Gene EpCAM in Human Corneal Epithelial Cells.  Transl Vis Sci Technol  2018    PubMed ID: 30619650   DOI: 10.1167/tvst.7.6.30
4118  Kandori S, Kojima T, Matsuoka T, Yoshino T, Sugiyama A, Nakamura E, Shimazui T, Funakoshi Y, Kanaho Y, Nishiyama H.  Phospholipase D2 promotes disease progression of renal cell carcinoma through the induction of angiogenin.  Cancer Sci.  2018    PubMed ID: 29660846   DOI: 10.1111/cas.13609
4119  Hirose Y, Onishi T, Miura S, Hatazawa Y, Kamei Y.  Vitamin D Attenuates FOXO1-Target Atrophy Gene Expression in C2C12 Muscle Cells.  J. Nutr. Sci. Vitaminol.  2018    PubMed ID: 29962435   DOI: 10.3177/jnsv.64.229
4120  Miyagawa Y, Matsushita Y, Suzuki H, Komatsu M, Yoshimaru T, Kimura R, Yanai A, Honda J, Tangoku A, Sasa M, Miyoshi Y, Katagiri T.  Frequent downregulation of LRRC26 by epigenetic alterations is involved in the malignant progression of triple-negative breast cancer.  Int. J. Oncol.  2018    PubMed ID: 29512727   DOI: 10.3892/ijo.2018.4301
4121  Kumeta M, Panina Y, Yamazaki H, Takeyasu K, Yoshimura SH.  N-terminal dual lipidation-coupled molecular targeting into the primary cilium.  Genes Cells  2018    PubMed ID: 29900630   DOI: 10.1111/gtc.12603
4122  Kato Y, Ninomiya K, Ohashi K, Tomida S, Makimoto G, Watanabe H, Kudo K, Matsumoto S, Umemura S, Goto K, Ichihara E, Ninomiya T, Kubo T, Sato A, Hotta K, Tabata M, Toyooka S, Maeda Y, Kiura K.  Combined effect of cabozantinib and gefitinib in crizotinib-resistant lung tumors harboring ROS1 fusions.  Cancer Sci.  2018    PubMed ID: 30053332   DOI: 10.1111/cas.13752
4279  Ito S, Ueno A, Ueda T, Nakagawa H, Taniguchi H, Kayukawa N, Fujihara-Iwata A, Hongo F, Okihara K, Ukimura O.  CNPY2 inhibits MYLIP-mediated AR protein degradation in prostate cancer cells.  Oncotarget  2018    PubMed ID: 29707137   DOI: 10.18632/oncotarget.24824
4465  Watanabe Y, Arai Y, Kawashita N, Ibrahim MS, Elgendy EM, Daidoji T, Kajikawa J, Hiramatsu H, Sriwilaijaroen N, Ono T, Takagi T, Takahashi K, Shioda T, Matsumoto K, Suzuki Y, Nakaya T.  Characterization of H5N1 Influenza Virus Quasispecies with Adaptive Hemagglutinin Mutations from Single-Virus Infections of Human Airway Cells.  J. Virol.  2018  92(11)  PubMed ID: 29563293   DOI: 10.1128/JVI.02004-17
4478  Omachi K, Kamura M, Teramoto K, Kojima H, Yokota T, Kaseda S, Kuwazuru J, Fukuda R, Koyama K, Matsuyama S, Motomura K, Shuto T, Suico MA, Kai H.  A Split-Luciferase-Based Trimer Formation Assay as a High-throughput Screening Platform for Therapeutics in Alport Syndrome.  Cell Chem Biol  2018  25(5):634-643.e4  PubMed ID: 29526710   DOI: 10.1016/j.chembiol.2018.02.003
9128  Asuka Yoshida, Ryoko Kawabata, Tomoyuki Honda, Kouji Sakai, Yasushi Ami, Takemasa Sakaguchi, Takashi Irie  A Single Amino Acid Substitution Within the Paramyxovirus Sendai Virus Nucleoprotein Is a Critical Determinant for Production of Interferon-Beta-Inducing Copyback-Type Defective Interfering Genomes  J Virol  2018  92 (5)   PubMed ID: 29237838   DOI: 10.1128/JVI.02094-17
14555  Iwai K, Yaguchi M, Nishimura K, Yamamoto Y, Tamura T, Nakata D, Dairiki R, Kawakita Y, Mizojiri R, Ito Y, Asano M, Maezaki H, Nakayama Y, Kaishima M, Hayashi K, Teratani M, Miyakawa S, Iwatani M, Miyamoto M, Klein MG, Lane W, Snell G, Tjhen R, He X, Pulukuri S, Nomura T.  Anti-tumor efficacy of a novel CLK inhibitor via targeting RNA splicing and MYC-dependent vulnerability  EMBO Mol Med  2018  10(6):e8289  PubMed ID: 29769258   DOI: 10.15252/emmm.201708289
14599  Senga S, Kawaguchi K, Kobayashi N, Ando A, Fujii H.  A novel fatty acid-binding protein 5-estrogen-related receptor α signaling pathway promotes cell growth and energy metabolism in prostate cancer cells  Oncotarget  2018  9(60):31753-31770  PubMed ID: 30167092   DOI: 10.18632/oncotarget.25878
14909  Iijima K, Kobayashi J, Ishizaka Y.  Structural alteration of DNA induced by viral protein R of HIV-1 triggers the DNA damage response  Retrovirology  2018  15(1):8  PubMed ID: 29338752   DOI: 10.1186/s12977-018-0391-8
15050  Kawabata Galbraith K, Fujishima K, Mizuno H, Lee SJ, Uemura T, Sakimura K, Mishina M, Watanabe N, Kengaku M.  MTSS1 Regulation of Actin-Nucleating Formin DAAM1 in Dendritic Filopodia Determines Final Dendritic Configuration of Purkinje Cells  Cell Rep  2018  24(1):95-106.e9  PubMed ID: 29972794   DOI: 10.1016/j.celrep.2018.06.013
15300  Matsumoto N, Sekiya M, Tohyama K, Ishiyama-Matsuura E, Sun-Wada GH, Wada Y, Futai M, Nakanishi-Matsui M.  Essential Role of the a3 Isoform of V-ATPase in Secretory Lysosome Trafficking via Rab7 Recruitmen  Sci Rep  2018  ;8(1):6701  PubMed ID: 29712939   DOI: 10.1038/s41598-018-24918-7
7011  Saito F, Hirayasu K, Satoh T, Wang CW, Lusingu J, Arimori T, Shida K, Palacpac NMQ, Itagaki S, Iwanaga S, Takashima E, Tsuboi T, Kohyama M, Suenaga T, Colonna M, Takagi J, Lavstsen T, Horii T, Arase H.  Immune evasion of Plasmodium falciparum by RIFIN via inhibitory receptors.  Nature  2017  552:101-105  PubMed ID: 29186116   DOI: 10.1038/nature24994
9875  Chung J, Aburaya S, Aoki W, Ueda M.  Molecular changes in appearance of a cancer cell among normal HEK293T cells.  J. Biosci. Bioeng.  2017  123:281-286  PubMed ID: 27777049   DOI: 10.1016/j.jbiosc.2016.09.012
10003  Takayama I, Tanabe H, Nishiyama T, Ito H, Amizuka N, Li M, Katsube KI, Kii I, Kudo A.  Periostin is required for matricellular localization of CCN3 in periodontal ligament of mice.  J Cell Commun Signal  2017  11:5-13  PubMed ID: 28013443   DOI: 10.1007/s12079-016-0371-5
10065  Matsui T, Hori A, Hamako J, Matsushita F, Ozeki Y, Sakurai Y, Hayakawa M, Matsumoto M, Fujimura Y.  Mutant botrocetin-2 inhibits von Willebrand factor-induced platelet agglutination.  J. Thromb. Haemost.  2017  15:538-548  PubMed ID: 28071872   DOI: 10.1111/jth.13617
10081  Tsukamoto T, Chiba Y, Nakazaki A, Ishikawa Y, Nakane Y, Cho Y, Yotsu-Yamashita M, Nishikawa T, Wakamori M, Konoki K.  Inhibition of veratridine-induced delayed inactivation of the voltage-sensitive sodium channel by synthetic analogs of crambescin B.  Bioorg. Med. Chem. Lett.  2017  27:1247-1251  PubMed ID: 28143690   DOI: 10.1016/j.bmcl.2017.01.054
10100  Mori J, Tanikawa C, Ohnishi N, Funauchi Y, Toyoshima O, Ueda K, Matsuda K.  EPSIN 3, A Novel p53 Target, Regulates the Apoptotic Pathway and Gastric Carcinogenesis.  Neoplasia  2017  19:185-195  PubMed ID: 28152424   DOI: 10.1016/j.neo.2016.12.010
10115  Hang Q, Isaji T, Hou S, Wang Y, Fukuda T, Gu J.  A Key Regulator of Cell Adhesion: Identification and Characterization of Important N-Glycosylation Sites on Integrin α5 for Cell Migration.  Mol. Cell. Biol.  2017  37:  PubMed ID: 28167607   DOI: 10.1128/MCB.00558-16
10136  Kawaguchi Y, Nariki H, Kawamoto N, Kanehiro Y, Miyazaki S, Suzuki M, Magari M, Tokumitsu H, Kanayama N.  SRSF1-3 contributes to diversification of the immunoglobulin variable region gene by promoting accumulation of AID in the nucleus.  Biochem. Biophys. Res. Commun.  2017  485:261-266  PubMed ID: 28235482   DOI: 10.1016/j.bbrc.2017.02.097
10163  Wada Y, Orba Y, Sasaki M, Kobayashi S, Carr MJ, Nobori H, Sato A, Hall WW, Sawa H.  Discovery of a novel antiviral agent targeting the nonstructural protein 4 (nsP4) of chikungunya virus.  Virology  2017  505:102-112  PubMed ID: 28236746   DOI: 10.1016/j.virol.2017.02.014
10164  Yamagata K, Kobayashi A.  The cysteine-rich domain of TET2 binds preferentially to mono- and dimethylated histone H3K36.  J. Biochem.  2017  161:327-330  PubMed ID: 28130413   DOI: 10.1093/jb/mvx004
10175  Tatebe H, Murayama S, Yonekura T, Hatano T, Richter D, Furuya T, Kataoka S, Furuita K, Kojima C, Shiozaki K.  Substrate specificity of TOR complex 2 is determined by a ubiquitin-fold domain of the Sin1 subunit.  Elife  2017  6:  PubMed ID: 28264193   DOI: 10.7554/eLife.19594
10218  Guo L, Elcioglu NH, Mizumoto S, Wang Z, Noyan B, Albayrak HM, Yamada S, Matsumoto N, Miyake N, Nishimura G, Ikegawa S.  Identification of biallelic EXTL3 mutations in a novel type of spondylo-epi-metaphyseal dysplasia.  J. Hum. Genet.  2017  62:797-801  PubMed ID: 28331220   DOI: 10.1038/jhg.2017.38
10232  Hashimoto H, Suda Y, Miyashita T, Ochiai A, Tsuboi M, Masutomi K, Kiyono T, Ishii G.  A novel method to generate single-cell-derived cancer-associated fibroblast clones.  J. Cancer Res. Clin. Oncol.  2017  143:1409-1419  PubMed ID: 28364361   DOI: 10.1007/s00432-017-2409-3
10235  Goyal S, Suzuki T, Li JR, Maeda S, Kishima M, Nishimura H, Shimizu Y, Suzuki H.  RUNX1 induces DNA replication independent active DNA demethylation at SPI1 regulatory regions.  BMC Mol. Biol.  2017  18:9  PubMed ID: 28376714   DOI: 10.1186/s12867-017-0087-y
10341  Hiwa R, Ohmura K, Arase N, Jin H, Hirayasu K, Kohyama M, Suenaga T, Saito F, Terao C, Atsumi T, Iwatani H, Mimori T, Arase H.  Myeloperoxidase/HLA Class II Complexes Recognized by Autoantibodies in Microscopic Polyangiitis.  Arthritis Rheumatol  2017  69:2069-2080  PubMed ID: 28575531   DOI: 10.1002/art.40170
10390  Takahashi Y, Tanikawa C, Miyamoto T, Hirata M, Wang G, Ueda K, Komatsu T, Matsuda K.  Regulation of tubular recycling endosome biogenesis by the p53-MICALL1 pathway.  Int. J. Oncol.  2017  51:724-736  PubMed ID: 28714518   DOI: 10.3892/ijo.2017.4060
10428  Ishii T, Homma K, Mano A, Akagi T, Shigematsu Y, Shimoda Y, Inoue H, Kakinuma Y, Kaneda M.  Novel channel-mediated choline transport in cholinergic neurons of the mouse retina.  J. Neurophysiol.  2017  118:1952-1961  PubMed ID: 28701543   DOI: 10.1152/jn.00506.2016
10456  Morita K, Maeda S, Suzuki K, Kiyose H, Taniguchi J, Liu PP, Sugiyama H, Adachi S, Kamikubo Y.  Paradoxical enhancement of leukemogenesis in acute myeloid leukemia with moderately attenuated RUNX1 expressions.  Blood Adv  2017  1:1440-1451  PubMed ID: 29296785   DOI: 10.1182/bloodadvances.2017007591
10541  Oda K, Oda T, Matoba Y, Sato M, Irie T, Sakaguchi T.  Structural analysis of the STAT1:STAT2 heterodimer revealed the mechanism of Sendai virus C protein-mediated blockade of type 1 interferon signaling.  J. Biol. Chem.  2017  292:19752-19766  PubMed ID: 28978648   DOI: 10.1074/jbc.M117.786285
10548  Hirano K, Namihira M.  FAD influx enhances neuronal differentiation of human neural stem cells by facilitating nuclear localization of LSD1.  FEBS Open Bio  2017  7:1932-1942  PubMed ID: 29226080   DOI: 10.1002/2211-5463.12331
10637  Yamamura T, Nozu K, Miyoshi Y, Nakanishi K, Fujimura J, Horinouchi T, Minamikawa S, Mori N, Fujimaru R, Nakanishi K, Ninchoji T, Kaito H, Mariko TI, Morioka I, Matsuo M, Iijima K.  An in vitro splicing assay reveals the pathogenicity of a novel intronic variant in ATP6V0A4 for autosomal recessive distal renal tubular acidosis.  BMC Nephrol  2017  18:353  PubMed ID: 29202719   DOI: 10.1186/s12882-017-0774-4
10642  Suzuki T, Maeda S, Furuhata E, Shimizu Y, Nishimura H, Kishima M, Suzuki H.  A screening system to identify transcription factors that induce binding site-directed DNA demethylation.  Epigenetics Chromatin  2017  10:60  PubMed ID: 29221486   DOI: 10.1186/s13072-017-0169-6
4545  Shichita T, Ito M, Morita R, Komai K, Noguchi Y, Ooboshi H, Koshida R, Takahashi S, Kodama T, Yoshimura A.  MAFB prevents excess inflammation after ischemic stroke by accelerating clearance of damage signals through MSR1.  Nat. Med.  2017  23(6):723-732  PubMed ID: 28394332   DOI: 10.1038/nm.4312
4548  Meng H, Yamashita C, Shiba-Fukushima K, Inoshita T, Funayama M, Sato S, Hatta T, Natsume T, Umitsu M, Takagi J, Imai Y, Hattori N.  Loss of Parkinson's disease-associated protein CHCHD2 affects mitochondrial crista structure and destabilizes cytochrome c.  Nat Commun  2017  8:15500  PubMed ID: 28589937   DOI: 10.1038/ncomms15500
5434  Nagasato AI, Yamashita H, Matsuo M, Ueda K, Kioka N.  The distribution of vinculin to lipid rafts plays an important role in sensing stiffness of extracellular matrix.  Biosci Biotechnol Biochem  2017  81(6):1136-1147  PubMed ID: 28485208   DOI: 10.1080/09168451.2017.1289074
9498  Jaerin Sohn, Megumu Takahashi, Shinichiro Okamoto, Yoko Ishida, Takahiro Furuta, Hiroyuki Hioki  A Single Vector Platform for High-Level Gene Transduction of Central Neurons: Adeno-Associated Virus Vector Equipped With the Tet-Off System  PLoS One  2017  12(1):e0169611  PubMed ID: 28060929   DOI: 10.1371/journal.pone.0169611
12287  Shigenori Inagaki, Hidekazu Tsutsui, Kazushi Suzuki, Masakazu Agetsuma, Yoshiyuki Arai, Yuka Jinno, Guirong Bai, Matthew J Daniels, Yasushi Okamura, Tomoki Matsuda, Takeharu Nagai   Genetically encoded bioluminescent voltage indicator for multi-purpose use in wide range of bioimaging  Sci Rep  2017  7:42398  PubMed ID: 28205521   DOI: 10.1038/srep42398
13814  Nakano T, Kanai Y, Amano Y, Yoshimoto T, Matsubara D, Shibano T, Tamura T, Oguni S, Katashiba S, Ito T, Murakami Y, Fukayama M, Murakami T, Endo S, Niki T.  Establishment of highly metastatic KRAS mutant lung cancer cell sublines in long-term three-dimensional low attachment cultures  PLoS Onec  2017  12(8):e0181342  PubMed ID: 28786996   DOI: 10.1371/journal.pone.0181342
13978  Fujitani M, Zhang S, Fujiki R, Fujihara Y, Yamashita T.  A chromosome 16p13.11 microduplication causes hyperactivity through dysregulation of miR-484/protocadherin-19 signaling  Mol Psychiatry  2017  22(3):364-374  PubMed ID: 27378146   DOI: 10.1038/mp.2016.106
14236  Okumura N, Kitahara M, Okuda H, Hashimoto K, Ueda E, Nakahara M, Kinoshita S, Young RD, Quantock AJ, Tourtas T, Schlötzer-Schrehardt U, Kruse F, Koizumi N.  Sustained Activation of the Unfolded Protein Response Induces Cell Death in Fuchs' Endothelial Corneal Dystrophy  Invest Ophthalmol Vis Sci  2017  58(9):3697-3707  PubMed ID: 28727885   DOI: 10.1167/iovs.16-21023
14257  Senga Y, Imamura H, Miyafusa T, Watanabe H, Honda S.  AlphaScreen-based homogeneous assay using a pair of 25-residue artificial proteins for high-throughput analysis of non-native IgG  Sci Rep  2017  7(1):12466  PubMed ID: 28963557   DOI: 10.1038/s41598-017-12693-w
14433  Endo H, Tanaka S, Imamura K, Adegawa S, Kikuta S, Sato R.  Cry toxin specificities of insect ABCC transporters closely related to lepidopteran ABCC2 transporters  Peptides  2017  98:86-92  PubMed ID: 28416297   DOI: 10.1016/j.peptides.2017.04.003
14594  Kano D, Nakagami Y, Kurihara H, Hosokawa S, Zenda S, Kusumoto M, Fujii H, Kaneta T, Saito S, Uesawa Y, Kagaya H.  Development of a double-stranded siRNA labelling method by using 99m Tc and single photon emission computed tomography imaging  J Drug Target  2017  25(2):172-178  PubMed ID: 27588821   DOI: 10.1080/1061186X.2016.1223675
14624  Tsukamoto T, Chiba Y, Wakamori M, Yamada T, Tsunogae S, Cho Y, Sakakibara R, Imazu T, Tokoro S, Satake Y, Adachi M, Nishikawa T, Yotsu-Yamashita M, Konoki K.  Differential binding of tetrodotoxin and its derivatives to voltage-sensitive sodium channel subtypes (Na v 1.1 to Na v 1.7)  Br J Pharmacol  2017  174(21):3881-3892  PubMed ID: 28832970   DOI: 10.1111/bph.13985
14704  Wu DC, Wang SSW, Liu CJ, Wuputra K, Kato K, Lee YL, Lin YC, Tsai MH, Ku CC, Lin WH, Wang SW, Kishikawa S, Noguchi M, Wu CC, Chen YT, Chai CY, Lin CS, Kuo KK, Yang YH, Miyoshi H, Nakamura Y, Saito S, Nagata K, Lin CS, Yokoyama KK.  Reprogramming Antagonizes the Oncogenicity of HOXA13-Long Noncoding RNA HOTTIP Axis in Gastric Cancer Cells  Stem Cells  2017  35(10):2115-2128  PubMed ID: 28782268   DOI: 10.1002/stem.2674
14749  Kikuta S, Watanabe SJ, Sato R, Gusev O, Nesmelov A, Sogame Y, Cornette R, Kikawada T.  Towards water-free biobanks: long-term dry-preservation at room temperature of desiccation-sensitive enzyme luciferase in air-dried insect cells  Sci Rep  2017  7(1):6540  PubMed ID: 28747745   DOI: 10.1038/s41598-017-06945-y
14759  Kobayashi JI, Hirasawa H, Ozawa T, Ozawa T, Takeda H, Fujimori Y, Nakanishi O, Kamada N, Ikeda T.  Synthesis and optimization of novel α-phenylglycinamides as selective TRPM8 antagonists  Bioorg Med Chem  2017  25(2):727-742  PubMed ID: 27964995   DOI: 10.1016/j.bmc.2016.11.049
14767  Elgendy EM, Arai Y, Kawashita N, Daidoji T, Takagi T, Ibrahim MS, Nakaya T, Watanabe Y.  Identification of polymerase gene mutations that affect viral replication in H5N1 influenza viruses isolated from pigeons  J Gen Virol   2017  98(1):6-17  PubMed ID: 27926816   DOI: 10.1099/jgv.0.000674
14777  Shigenori Inagaki, Masakazu Agetsuma, Shinya Ohara, Toshio Iijima, Tetsuichi Wazawa, Yoshiyuki Arai, Takeharu Nagai  In vivo brain activity imaging of interactively locomoting mice  bioRxiv   2017  October 15, 2017    DOI: 10.1101/203422
16633  Khedgikar V, Abbruzzese G, Mathavan K, Szydlo H, Cousin H, Alfandari D.  Dual control of pcdh8l/PCNS expression and function in Xenopus laevis neural crest cells by adam13/33 via the transcription factors tfap2α and arid3a  Elife  2017  6:e26898  PubMed ID: 28829038   DOI: 10.7554/eLife.26898
7048  Suzuki K, Kimura T, Shinoda H, Bai G, Daniels MJ, Arai Y, Nakano M, Nagai T.  Five colour variants of bright luminescent protein for real-time multicolour bioimaging.  Nat Commun  2016  7:13718  PubMed ID: 27966527   DOI: 10.1038/ncomms13718
7056  Funato H, Miyoshi C, Fujiyama T, Kanda T, Sato M, Wang Z, Ma J, Nakane S, Tomita J, Ikkyu A, Kakizaki M, Hotta-Hirashima N, Kanno S, Komiya H, Asano F, Honda T, Kim SJ, Harano K, Muramoto H, Yonezawa T, Mizuno S, Miyazaki S, Connor L, Kumar V, Miura I, Suzuki T, Watanabe A, Abe M, Sugiyama F, Takahashi S, Sakimura K, Hayashi Y, Liu Q, Kume K, Wakana S, Takahashi JS, Yanagisawa M.  Forward-genetics analysis of sleep in randomly mutagenized mice.  Nature  2016  539:378-383  PubMed ID: 27806374   DOI: 10.1038/nature20142
7060  Kanda S, Yanagitani K, Yokota Y, Esaki Y, Kohno K.  Autonomous translational pausing is required for XBP1u mRNA recruitment to the ER via the SRP pathway.  Proc. Natl. Acad. Sci. U.S.A.  2016  113:E5886-E5895  PubMed ID: 27651490   DOI: 10.1073/pnas.1604435113
7062  Hashimoto T, Horikawa DD, Saito Y, Kuwahara H, Kozuka-Hata H, Shin-I T, Minakuchi Y, Ohishi K, Motoyama A, Aizu T, Enomoto A, Kondo K, Tanaka S, Hara Y, Koshikawa S, Sagara H, Miura T, Yokobori S, Miyagawa K, Suzuki Y, Kubo T, Oyama M, Kohara Y, Fujiyama A, Arakawa K, Katayama T, Toyoda A, Kunieda T.  Extremotolerant tardigrade genome and improved radiotolerance of human cultured cells by tardigrade-unique protein.  Nat Commun  2016  7:12808  PubMed ID: 27649274   DOI: 10.1038/ncomms12808
7063  Morita S, Noguchi H, Horii T, Nakabayashi K, Kimura M, Okamura K, Sakai A, Nakashima H, Hata K, Nakashima K, Hatada I.  Targeted DNA demethylation in vivo using dCas9-peptide repeat and scFv-TET1 catalytic domain fusions.  Nat. Biotechnol.  2016  34:1060-1065  PubMed ID: 27571369   DOI: 10.1038/nbt.3658
7069  Kataoka K, Shiraishi Y, Takeda Y, Sakata S, Matsumoto M, Nagano S, Maeda T, Nagata Y, Kitanaka A, Mizuno S, Tanaka H, Chiba K, Ito S, Watatani Y, Kakiuchi N, Suzuki H, Yoshizato T, Yoshida K, Sanada M, Itonaga H, Imaizumi Y, Totoki Y, Munakata W, Nakamura H, Hama N, Shide K, Kubuki Y, Hidaka T, Kameda T, Masuda K, Minato N, Kashiwase K, Izutsu K, Takaori-Kondo A, Miyazaki Y, Takahashi S, Shibata T, Kawamoto H, Akatsuka Y, Shimoda K, Takeuchi K, Seya T, Miyano S, Ogawa S.  Aberrant PD-L1 expression through 3'-UTR disruption in multiple cancers.  Nature  2016  534:402-6  PubMed ID: 27281199   DOI: 10.1038/nature18294
7133  Ichijo Y, Mochimaru Y, Azuma M, Satou K, Negishi J, Nakakura T, Oshima N, Mogi C, Sato K, Matsuda K, Okajima F, Tomura H.  Two zebrafish G2A homologs activate multiple intracellular signaling pathways in acidic environment.  Biochem. Biophys. Res. Commun.  2016  469:81-86  PubMed ID: 26614909   DOI: 10.1016/j.bbrc.2015.11.075
7262  Kikuta S, Hou BH, Sato R, Frommer WB, Kikawada T.  FRET sensor-based quantification of intracellular trehalose in mammalian cells.  Biosci. Biotechnol. Biochem.  2016  80:162-5  PubMed ID: 26214383   DOI: 10.1080/09168451.2015.1069699
9560  Hagiwara A, Ogiwara K, Takahashi T.  Expression of Membrane Progestin Receptors (mPRs) in Granulosa Cells of Medaka Preovulatory Follicles.  Zool. Sci.  2016  33:98-105  PubMed ID: 26853875   DOI: 10.2108/zs150093
9627  Koguchi T, Tanikawa C, Mori J, Kojima Y, Matsuda K.  Regulation of myo-inositol biosynthesis by p53-ISYNA1 pathway.  Int. J. Oncol.  2016  48:2415-24  PubMed ID: 27035231   DOI: 10.3892/ijo.2016.3456
9649  Tsuchiya M, Niwa Y, Simizu S.  N-glycosylation of R-spondin1 at Asn137 negatively regulates its secretion and Wnt/β-catenin signaling-enhancing activity.  Oncol Lett  2016  11:3279-3286  PubMed ID: 27123103   DOI: 10.3892/ol.2016.4425
9664  Tanaka H, Fujiwara H, Ochi F, Tanimoto K, Casey N, Okamoto S, Mineno J, Kuzushima K, Shiku H, Sugiyama T, Barrett AJ, Yasukawa M.  Development of Engineered T Cells Expressing a Chimeric CD16-CD3ζ Receptor to Improve the Clinical Efficacy of Mogamulizumab Therapy Against Adult T-Cell Leukemia.  Clin. Cancer Res.  2016  22:4405-16  PubMed ID: 27091408   DOI: 10.1158/1078-0432.CCR-15-2714
9671  Hirayasu K, Saito F, Suenaga T, Shida K, Arase N, Oikawa K, Yamaoka T, Murota H, Chibana H, Nakagawa I, Kubori T, Nagai H, Nakamaru Y, Katayama I, Colonna M, Arase H.  Microbially cleaved immunoglobulins are sensed by the innate immune receptor LILRA2.  Nat Microbiol  2016  1:16054  PubMed ID: 27572839   DOI: 10.1038/nmicrobiol.2016.54
9783  Khanom R, Nguyen CT, Kayamori K, Zhao X, Morita K, Miki Y, Katsube K, Yamaguchi A, Sakamoto K.  Keratin 17 Is Induced in Oral Cancer and Facilitates Tumor Growth.  PLoS ONE  2016  11:e0161163  PubMed ID: 27512993   DOI: 10.1371/journal.pone.0161163
9793  Yamaura K, Kiyonaka S, Numata T, Inoue R, Hamachi I.  Discovery of allosteric modulators for GABAA receptors by ligand-directed chemistry.  Nat. Chem. Biol.  2016  12:822-30  PubMed ID: 27526031   DOI: 10.1038/nchembio.2150
9807  Kobayashi T, Yagi Y, Nakamura T.  Development of Genome Engineering Tools from Plant-Specific PPR Proteins Using Animal Cultured Cells.  Methods Mol. Biol.  2016  1469:147-55  PubMed ID: 27557692   DOI: 10.1007/978-1-4939-4931-1_11
9843  Kondoh Y, Honda K, Hiranuma S, Hayashi T, Shimizu T, Watanabe N, Osada H.  Comparative chemical array screening for p38γ/δ MAPK inhibitors using a single gatekeeper residue difference between p38α/β and p38γ/δ.  Sci Rep  2016  6:29881  PubMed ID: 27431267   DOI: 10.1038/srep29881
9845  Hazawa M, Yasuda T, Saotome-Nakamura A, Tomiyama K, Obara C, Goto T, Tajima K.  Intra- and extracellular plasminogen activator inhibitor-1 regulate effect of vitronectin against radiation-induced endothelial cell death.  Vascul. Pharmacol.  2016  87:150-158  PubMed ID: 27650166   DOI: 10.1016/j.vph.2016.09.006
9846  Hang Q, Isaji T, Hou S, Zhou Y, Fukuda T, Gu J.  N-Glycosylation of integrin α5 acts as a switch for EGFR-mediated complex formation of integrin α5β1 to α6β4.  Sci Rep  2016  6:33507  PubMed ID: 27641064   DOI: 10.1038/srep33507
9908  Kurita K, Maeda M, Mansour MA, Kokuryo T, Uehara K, Yokoyama Y, Nagino M, Hamaguchi M, Senga T.  TRIP13 is expressed in colorectal cancer and promotes cancer cell invasion.  Oncol Lett  2016  12:5240-5246  PubMed ID: 28105232   DOI: 10.3892/ol.2016.5332
9916  Nishimura T, Ito S, Saito H, Hiver S, Shigetomi K, Ikenouchi J, Takeichi M.  DAAM1 stabilizes epithelial junctions by restraining WAVE complex-dependent lateral membrane motility.  J. Cell Biol.  2016  215:559-573  PubMed ID: 27807130   DOI: 10.1083/jcb.201603107
10012  Ohtsuka T, Sakaguchi M, Yamamoto H, Tomida S, Takata K, Shien K, Hashida S, Miyata-Takata T, Watanabe M, Suzawa K, Soh J, Youyi C, Sato H, Namba K, Torigoe H, Tsukuda K, Yoshino T, Miyoshi S, Toyooka S.  Interaction of cytokeratin 19 head domain and HER2 in the cytoplasm leads to activation of HER2-Erk pathway.  Sci Rep  2016  6:39557  PubMed ID: 28008968   DOI: 10.1038/srep39557
10015  Hirayama S, Hori Y, Benedek Z, Suzuki T, Kikuchi K.  Fluorogenic probes reveal a role of GLUT4 N-glycosylation in intracellular trafficking.  Nat. Chem. Biol.  2016  12:853-9  PubMed ID: 27547921   DOI: 10.1038/nchembio.2156
10016  Hou S, Hang Q, Isaji T, Lu J, Fukuda T, Gu J.  Importance of membrane-proximal N-glycosylation on integrin β1 in its activation and complex formation.  FASEB J.  2016  30:4120-4131  PubMed ID: 27565712   DOI: 10.1096/fj.201600665R
12288  Kung-Kai Kuo, King-Teh Lee, Ker-Kong Chen, Ya-Han Yang, Ying-Chu Lin, Ming-Ho Tsai, Kenly Wuputra, Yen-Liang Lee, Chia-Chen Ku, Hiroyuki Miyoshi, Yukio Nakamura, Shigeo Saito, Chun-Chieh Wu, Chee-Yin Chai, Richard Eckner, Chen-Lung Steve Lin, Sophie S-W Wang, Deng-Chyang Wu, Chang-Shen Lin, Kazunari K Yokoyama  Positive Feedback Loop of OCT4 and c-JUN Expedites Cancer Stemness in Liver Cancer  Stem Cells  2016  34(11):2613-2624  PubMed ID: 27341307   DOI: 10.1002/stem.2447
12627  Elmansuri AZ, Tanino MA, Mahabir R, Wang L, Kimura T, Nishihara H, Kinoshita I, Dosaka-Akita H, Tsuda M, Tanaka S.  Novel signaling collaboration between TGF-β and adaptor protein Crk facilitates EMT in human lung cancer  Oncotarget   2016  7(19):27094-107  PubMed ID: 27027347   DOI: 10.18632/oncotarget.8314
12670  Mori J, Tanikawa C, Funauchi Y, Lo PH, Nakamura Y, Matsuda K.  Cystatin C as a p53-inducible apoptotic mediator that regulates cathepsin L activity  Cancer Sci  2016  107(3):298-306  PubMed ID: 26757339   DOI: 10.1111/cas.12881
12671  Lu J, Isaji T, Im S, Fukuda T, Kameyama A, Gu J.  Expression of N-Acetylglucosaminyltransferase III Suppresses α2,3-Sialylation, and Its Distinctive Functions in Cell Migration Are Attributed to α2,6-Sialylation Levels  J Biol Chem  2016  291(11):5708-20  PubMed ID: 26801611   DOI: 10.1074/jbc.M115.712836
12894  Sohn J, Okamoto S, Kataoka N, Kaneko T, Nakamura K, Hioki H.  Differential Inputs to the Perisomatic and Distal-Dendritic Compartments of VIP-Positive Neurons in Layer 2/3 of the Mouse Barrel Cortex  Front Neuroanat  2016  10:124  PubMed ID: 28066195   DOI: 10.3389/fnana.2016.00124
12923  Ryuzono S, Takase R, Oishi K, Ikeda A, Chigwechokha PK, Funahashi A, Komatsu M, Miyagi T, Shiozaki K.  Lysosomal localization of Japanese medaka (Oryzias latipes) Neu1 sialidase and its highly conserved enzymatic profiles with human  Gene  2016  575(2 Pt 2):513-523.  PubMed ID: 26432003   DOI: 10.1016/j.gene.2015.09.028
12933  Obayashi M, Yoshida M, Tsunematsu T, Ogawa I, Sasahira T, Kuniyasu H, Imoto I, Abiko Y, Xu D, Fukunaga S, Tahara H, Kudo Y, Nagao T, Takata T.  microRNA-203 suppresses invasion and epithelial-mesenchymal transition induction via targeting NUAK1 in head and neck cancer  Oncotarget  2016  7(7):8223-39  PubMed ID: 26882562   DOI: 10.18632/oncotarget.6972
12941  Saho S, Satoh H, Kondo E, Inoue Y, Yamauchi A, Murata H, Kinoshita R, Yamamoto KI, Futami J, Putranto EW, Ruma IM, Sumardika IW, Youyi C, Suzawa K, Yamamoto H, Soh J, Tomida S, Sakaguchi Y, Saito K, Iioka H, Huh NH, Toyooka S, Sakaguchi M.  Active Secretion of Dimerized S100A11 Induced by the Peroxisome in Mesothelioma Cells  Cancer Microenviron  2016  9(2-3):93-105  PubMed ID: 27334300   DOI: 10.1007/s12307-016-0185-2
13460  Miyake T, Kumasawa K, Sato N, Takiuchi T, Nakamura H, Kimura T.  Soluble VEGF receptor 1 (sFLT1) induces non-apoptotic death in ovarian and colorectal cancer cells  Sci Rep  2016  6:24853  PubMed ID: 27103202   DOI: 10.1038/srep24853
13471  Wang SS, Wuputra K, Liu CJ, Lin YC, Chen YT, Chai CY, Lin CS, Kuo KK, Tsai MH, Wang SW, Chen KK, Miyoshi H, Nakamura Y, Saito S, Hanafusa T, Wu DC, Lin CS, Yokoyama KK.  Oncogenic function of the homeobox A13-long noncoding RNA HOTTIP-insulin growth factor-binding protein 3 axis in human gastric cancer  Oncotarget  2016  7(24):36049-36064  PubMed ID: 27144338   DOI: 10.18632/oncotarget.9102
14024  Yasuhira S, Shibazaki M, Nishiya M, Maesawa C.  Paclitaxel-induced aberrant mitosis and mitotic slippage efficiently lead to proliferative death irrespective of canonical apoptosis and p53  Cell Cycle  2016  15(23):3268-3277  PubMed ID: 27764550   DOI: 10.1080/15384101.2016.1242537
14114  Sakamoto Y, Kanatsu J, Toh M, Naka A, Kondo K, Iida K.  The Dietary Isoflavone Daidzein Reduces Expression of Pro-Inflammatory Genes through PPARα/γ and JNK Pathways in Adipocyte and Macrophage Co-Cultures  PLoS One  2016  11(2):e0149676  PubMed ID: 26901838   DOI: 10.1371/journal.pone.0149676
14151  Hou S, Isaji T, Hang Q, Im S, Fukuda T, Gu J.  Distinct effects of β1 integrin on cell proliferation and cellular signaling in MDA-MB-231 breast cancer cells  Sci Rep  2016  6:18430  PubMed ID: 26728650   DOI: 10.1038/srep18430
14157  Sakuma T, Nakade S, Sakane Y, Suzuki KT, Yamamoto T.  MMEJ-assisted gene knock-in using TALENs and CRISPR-Cas9 with the PITCh systems  Nat Protoc  2016  11(1):118-33  PubMed ID: 26678082   DOI: 10.1038/nprot.2015.140
14158  Johmura Y, Sun J, Kitagawa K, Nakanishi K, Kuno T, Naiki-Ito A, Sawada Y, Miyamoto T, Okabe A, Aburatani H, Li S, Miyoshi I, Takahashi S, Kitagawa M, Nakanishi M.  SCF(Fbxo22)-KDM4A targets methylated p53 for degradation and regulates senescence  Nat Commun  2016  7:10574  PubMed ID: 26868148   DOI: 10.1038/ncomms10574
14168  Kikuta S, Endo H, Tomita N, Takada T, Morita C, Asaoka K, Sato R.  Characterization of a ligand-gated cation channel based on an inositol receptor in the silkworm, Bombyx mori  Insect Biochem Mol Biol  2016  74:12-20  PubMed ID: 27132146   DOI: 10.1016/j.ibmb.2016.04.010
14176  Tetsuo Koshizuka, Keiichiro Tanaka, Tatsuo Suzutani  Degradation of host ubiquitin E3 ligase Itch by human cytomegalovirus UL42  Journal of General Virology  2016  97:196-208  PubMed ID: 26555021   DOI: 10.1099/jgv.0.000336
14950  Mang D, Shu M, Endo H, Yoshizawa Y, Nagata S, Kikuta S, Sato R.  Expression of a sugar clade gustatory receptor, BmGr6, in the oral sensory organs, midgut, and central nervous system of larvae of the silkworm Bombyx mori  Insect Biochem Mol Biol  2016  70:85-98  PubMed ID: 26721200   DOI: 10.1016/j.ibmb.2015.12.008
7180  Hang Q, Isaji T, Hou S, Im S, Fukuda T, Gu J.  Integrin α5 Suppresses the Phosphorylation of Epidermal Growth Factor Receptor and Its Cellular Signaling of Cell Proliferation via N-Glycosylation.  J. Biol. Chem.  2015  290:29345-60  PubMed ID: 26483551   DOI: 10.1074/jbc.M115.682229
7190  Kataoka K, Nagata Y, Kitanaka A, Shiraishi Y, Shimamura T, Yasunaga J, Totoki Y, Chiba K, Sato-Otsubo A, Nagae G, Ishii R, Muto S, Kotani S, Watatani Y, Takeda J, Sanada M, Tanaka H, Suzuki H, Sato Y, Shiozawa Y, Yoshizato T, Yoshida K, Makishima H, Iwanaga M, Ma G, Nosaka K, Hishizawa M, Itonaga H, Imaizumi Y, Munakata W, Ogasawara H, Sato T, Sasai K, Muramoto K, Penova M, Kawaguchi T, Nakamura H, Hama N, Shide K, Kubuki Y, Hidaka T, Kameda T, Nakamaki T, Ishiyama K, Miyawaki S, Yoon SS, Tobinai K, Miyazaki Y, Takaori-Kondo A, Matsuda F, Takeuchi K, Nureki O, Aburatani H, Watanabe T, Shibata T, Matsuoka M, Miyano S, Shimoda K, Ogawa S.  Integrated molecular analysis of adult T cell leukemia/lymphoma.  Nat. Genet.  2015  47:1304-15  PubMed ID: 26437031   DOI: 10.1038/ng.3415
7216  Aoki N, Yamaguchi S, Kitajima T, Takehara A, Katagiri-Nakagawa S, Matsui R, Watanabe D, Matsushima T, Homma KJ.  Critical role of the neural pathway from the intermediate medial mesopallium to the intermediate hyperpallium apicale in filial imprinting of domestic chicks (Gallus gallus domesticus).  Neuroscience  2015  308:115-24  PubMed ID: 26362886   DOI: 10.1016/j.neuroscience.2015.09.014
7242  Okumura N, Minamiyama R, Ho LT, Kay EP, Kawasaki S, Tourtas T, Schlotzer-Schrehardt U, Kruse FE, Young RD, Quantock AJ, Kinoshita S, Koizumi N.  Involvement of ZEB1 and Snail1 in excessive production of extracellular matrix in Fuchs endothelial corneal dystrophy.  Lab. Invest.  2015  95:1291-304  PubMed ID: 26302187   DOI: 10.1038/labinvest.2015.111
7252  Ichikawa T, Nakahata S, Fujii M, Iha H, Morishita K.  Loss of NDRG2 enhanced activation of the NF-κB pathway by PTEN and NIK phosphorylation for ATL and other cancer development.  Sci Rep  2015  5:12841  PubMed ID: 26269411   DOI: 10.1038/srep12841
7263  Ichikawa T, Nakahata S, Tamura T, Manachai N, Morishita K.  The loss of NDRG2 expression improves depressive behavior through increased phosphorylation of GSK3β.  Cell. Signal.  2015  27:2087-98  PubMed ID: 26208882   DOI: 10.1016/j.cellsig.2015.07.012
7274  Tohmonda T, Yoda M, Iwawaki T, Matsumoto M, Nakamura M, Mikoshiba K, Toyama Y, Horiuchi K.  IRE1α/XBP1-mediated branch of the unfolded protein response regulates osteoclastogenesis.  J. Clin. Invest.  2015  125:3269-79  PubMed ID: 26193638   DOI: 10.1172/JCI76765
7371  Kimura T, Endo S, Inui M, Saitoh S, Miyake K, Takai T.  Endoplasmic Protein Nogo-B (RTN4-B) Interacts with GRAMD4 and Regulates TLR9-Mediated Innate Immune Responses.  J. Immunol.  2015  194:5426-36  PubMed ID: 25917084   DOI: 10.4049/jimmunol.1402006
7393  Ito T, Hioki H, Sohn J, Okamoto S, Kaneko T, Iino S, Oliver DL.  Convergence of Lemniscal and Local Excitatory Inputs on Large GABAergic Tectothalamic Neurons.  J. Comp. Neurol.  2015  523:2277-96  PubMed ID: 25879870   DOI: 10.1002/cne.23789
7426  Nakazato R, Takarada T, Ikeno S, Nakamura S, Kutsukake T, Hinoi E, Yoneda Y.  Upregulation of Runt-Related Transcription Factor-2 Through CCAAT Enhancer Binding Protein-β Signaling Pathway in Microglial BV-2 Cells Exposed to ATP.  J. Cell. Physiol.  2015  230:2510-21  PubMed ID: 25802132   DOI: 10.1002/jcp.24988
7435  Ebina H, Kanemura Y, Misawa N, Sakuma T, Kobayashi T, Yamamoto T, Koyanagi Y.  A high excision potential of TALENs for integrated DNA of HIV-based lentiviral vector.  PLoS ONE  2015  10:e0120047  PubMed ID: 25781496   DOI: 10.1371/journal.pone.0120047
7468  Masuda K, Chiyoda T, Sugiyama N, Segura-Cabrera A, Kabe Y, Ueki A, Banno K, Suematsu M, Aoki D, Ishihama Y, Saya H, Kuninaka S.  LATS1 and LATS2 phosphorylate CDC26 to modulate assembly of the tetratricopeptide repeat subcomplex of APC/C.  PLoS ONE  2015  10:e0118662  PubMed ID: 25723520   DOI: 10.1371/journal.pone.0118662
7514  Mochimaru Y, Azuma M, Oshima N, Ichijo Y, Satou K, Matsuda K, Asaoka Y, Nishina H, Nakakura T, Mogi C, Sato K, Okajima F, Tomura H.  Extracellular acidification activates ovarian cancer G-protein-coupled receptor 1 and GPR4 homologs of zebra fish.  Biochem. Biophys. Res. Commun.  2015  457:493-9  PubMed ID: 25576873   DOI: 10.1016/j.bbrc.2014.12.105
3744  Nakamura R, Oyama T, Tajiri R, Mizokami A, Namiki M, Nakamoto M, Ooi A.  Expression and regulatory effects on cancer cell behavior of NELL1 and NELL2 in human renal cell carcinoma.  Cancer Sci  2015  106(5):656-64  PubMed ID: 25726761   DOI: 10.1111/cas.12649
9488  Tadahiro Suenaga, Maki Matsumoto, Fuminori Arisawa, Masako Kohyama, Kouyuki Hirayasu, Yasuko Mori, Hisashi Arase  Sialic Acids on Varicella-Zoster Virus Glycoprotein B Are Required for Cell-Cell Fusion  J Biol Chem  2015  290(32):19833-43  PubMed ID: 26105052   DOI: 10.1074/jbc.M114.635508
14284  Bill A, Gutierrez A, Kulkarni S, Kemp C, Bonenfant D, Voshol H, Duvvuri U, Gaither LA.  ANO1/TMEM16A interacts with EGFR and correlates with sensitivity to EGFR-targeting therapy in head and neck cancer  Oncotarget  2015  6(11):9173-88  PubMed ID: 25823819   DOI: 10.18632/oncotarget.3277
15063  Tanaka S, Tanaka J, Miwa Y, Horikawa DD, Katayama T, Arakawa K, Toyoda A, Kubo T, Kunieda T.  Novel mitochondria-targeted heat-soluble proteins identified in the anhydrobiotic Tardigrade improve osmotic tolerance of human cells  PLoS One  2015  10(2):e0118272  PubMed ID: 25675104   DOI: 10.1371/journal.pone.0118272
15189  Shinmyo Y, Asrafuzzaman Riyadh M, Ahmed G, Bin Naser I, Hossain M, Takebayashi H, Kawasaki H, Ohta K, Tanaka H.  Draxin from neocortical neurons controls the guidance of thalamocortical projections into the neocortex  Nat Commun  2015  6:10232  PubMed ID: 26659141   DOI: 10.1038/ncomms10232
15213  Suzuki Y, Kiyokage E, Sohn J, Hioki H, Toida K.  Structural basis for serotonergic regulation of neural circuits in the mouse olfactory bulb  J Comp Neurol   2015  523(2):262-80  PubMed ID: 25234191   DOI: 10.1002/cne.23680
15222  Ohishi K, Toume K, Arai MA, Koyano T, Kowithayakorn T, Mizoguchi T, Itoh M, Ishibashi M.  9-Hydroxycanthin-6-one, a β-Carboline Alkaloid from Eurycoma longifolia, Is the First Wnt Signal Inhibitor through Activation of Glycogen Synthase Kinase 3β without Depending on Casein Kinase 1α  J Nat Prod  2015  78(5):1139-46  PubMed ID: 25905468   DOI: 10.1021/acs.jnatprod.5b00153
15239  Wakimoto T, Uchida K, Mimura K, Kanagawa T, Mehandjiev TR, Aoshima H, Kokubo K, Mitsuda N, Yoshioka Y, Tsutsumi Y, Kimura T, Yanagihara I.  Hydroxylated fullerene: a potential antiinflammatory and antioxidant agent for preventing mouse preterm birth  Am J Obstet Gynecol  2015  213(5):708.e1-9  PubMed ID: 26196453   DOI: 10.1016/j.ajog.2015.07.017
15258  Yamanishi M, Narazaki H, Asano T.  Melatonin overcomes resistance to clofarabine in two leukemic cell lines by increased expression of deoxycytidine kinase  Exp Hematol  2015  43(3):207-14  PubMed ID: 25461250   DOI: 10.1016/j.exphem.2014.11.001
15452  Konoki K, Suga Y, Fuwa H, Yotsu-Yamashita M, Sasaki M.  Evaluation of gambierol and its analogs for their inhibition of human Kv1.2 and cytotoxicity  Bioorg Med Chem Lett  2015  ;25(3):514-8  PubMed ID: 25556093   DOI: 10.1016/j.bmcl.2014.12.022
10171  Fujiwara H, Ochi T, Ochi F, Miyazaki Y, Asai H, Narita M, Okamoto S, Mineno J, Kuzushima K, Shiku H, Yasukawa M.  Antileukemia multifunctionality of CD4(+) T cells genetically engineered by HLA class I-restricted and WT1-specific T-cell receptor gene transfer  Leukemia  2015  29(12):2393-401  PubMed ID: 26104661   DOI: 10.1038/leu.2015.155
18179  Chiba S, Ikushima H, Ueki H, Yanai H, Kimura Y, Hangai S, Nishio J, Negishi H, Tamura T, Saijo S, Iwakura Y, Taniguchi T.  Recognition of tumor cells by Dectin-1 orchestrates innate immune cells for anti-tumor responses  Elife  2014  3:e04177  PubMed ID: 25149452   DOI: 10.7554/eLife.04177
7579  Suzuki-Nakagawa C, Nishimura M, Tsukamoto T, Aoyama S, Ebihara A, Suzuki F, Nakagawa T.  Participation of the extracellular domain in (pro)renin receptor dimerization.  Biochem. Biophys. Res. Commun.  2014  444:461-6  PubMed ID: 24472541   DOI: 10.1016/j.bbrc.2014.01.073
5836  Saito K, Sakaguchi M, Iioka H, Matsui M, Nakanishi H, Huh NH, Kondo E.  Coxsackie and adenovirus receptor is a critical regulator for the survival and growth of oral squamous carcinoma cells.  Oncogene  2014  33(10):1274-86  PubMed ID: 23503462   DOI: 10.1038/onc.2013.66
14940  Okumura N, Hirano H, Numata R, Nakahara M, Ueno M, Hamuro J, Kinoshita S, Koizumi N.  Cell surface markers of functional phenotypic corneal endothelial cells  Invest Ophthalmol Vis Sci  2014  55(11):7610-8  PubMed ID: 25389199   DOI: 10.1167/iovs.14-14980
15805  Murakami-Tonami Y, Kishida S, Takeuchi I, Katou Y, Maris JM, Ichikawa H, Kondo Y, Sekido Y, Shirahige K, Murakami H, Kadomatsu K.  Inactivation of SMC2 shows a synergistic lethal response in MYCN-amplified neuroblastoma cells  Cell Cycle  2014  13(7):1115-31  PubMed ID: 24553121   DOI: 10.4161/cc.27983
15812  Yamashita H, Ichikawa T, Matsuyama D, Kimura Y, Ueda K, Craig SW, Harada I, Kioka N.  The role of the interaction of the vinculin proline-rich linker region with vinexin α in sensing the stiffness of the extracellular matrix  J Cell Sci   2014  127(Pt 9):1875-86  PubMed ID: 24554436   DOI: 10.1242/jcs.133645
15829  Miyagawa-Yamaguchi A, Kotani N, Honke K.  Expressed glycosylphosphatidylinositol-anchored horseradish peroxidase identifies co-clustering molecules in individual lipid raft domains  PLoS One  2014  9(3):e93054  PubMed ID: 24671047   DOI: 10.1371/journal.pone.0093054
16652  Lu J, Isaji T, Im S, Fukuda T, Hashii N, Takakura D, Kawasaki N, Gu J.  β-Galactoside α2,6-sialyltranferase 1 promotes transforming growth factor-β-mediated epithelial-mesenchymal transition  J Biol Chem  2014  289(50):34627-41  PubMed ID: 25344606   DOI: 10.1074/jbc.M114.593392
17086  Ishikawa F, Kaneko E, Sugimoto T, Ishijima T, Wakamatsu M, Yuasa A, Sampei R, Mori K, Nose K, Shibanuma M.  A mitochondrial thioredoxin-sensitive mechanism regulates TGF-β-mediated gene expression associated with epithelial-mesenchymal transition  Biochem Biophys Res Commun  2014  443(3):821-7  PubMed ID: 24342608   DOI: 10.1016/j.bbrc.2013.12.050
17090  Park HY, Toume K, Arai MA, Sadhu SK, Ahmed F, Ishibashi M.  Calotropin: a cardenolide from calotropis gigantea that inhibits Wnt signaling by increasing casein kinase 1α in colon cancer cells  Chembiochem  2014  15(6):872-8.  PubMed ID: 24644251   DOI: 10.1002/cbic.201300786
17143  Takano M, Kanoh A, Amako K, Otani M, Sano K, Kanazawa-Hamada M, Matsuyama S.  Nuclear localization of bradykinin B(2) receptors reflects binding to the nuclear envelope protein lamin C  Eur J Pharmacol  2014  723:507-14  PubMed ID: 24211782   DOI: 10.1016/j.ejphar.2013.09.054
18274  Goudarzi H, Hida Y, Takano H, Teramae H, Iizasa H, Hamada J.  Hypoxia affects in vitro growth of newly established cell lines from patients with malignant pleural mesothelioma  Biomed Res  2013  34(1):13-21  PubMed ID: 23428976   DOI: 10.2220/biomedres.34.13
18597  Akimoto AM, Takarada T, Maeda M.  Preparation of cell-culturing glass surfaces that release branched polyethyleneimine triggered by thiol-disulfide exchange  Colloids Surf B Biointerfaces  2013  103:360-5  PubMed ID: 23261556   DOI: 10.1016/j.colsurfb.2012.10.031
6082  Ohnishi H, Sasaki H, Nakamura Y, Kato S, Ando K, Narimatsu H, Tachibana K.  Regulation of cell shape and adhesion by CD34  Cell Adh Migr  2013  7(5):426-33  PubMed ID: 24036614   DOI: 10.4161/cam.25957
15792  Kon A, Shih LY, Minamino M, Sanada M, Shiraishi Y, Nagata Y, Yoshida K, Okuno Y, Bando M, Nakato R, Ishikawa S, Sato-Otsubo A, Nagae G, Nishimoto A, Haferlach C, Nowak D, Sato Y, Alpermann T, Nagasaki M, Shimamura T, Tanaka H, Chiba K, Yamamoto R, Yamaguchi T, Otsu M, Obara N, Sakata-Yanagimoto M, Nakamaki T, Ishiyama K, Nolte F, Hofmann WK, Miyawaki S, Chiba S, Mori H, Nakauchi H, Koeffler HP, Aburatani H, Haferlach T, Shirahige K, Miyano S, Ogawa S.  Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms  Nat Genet  2013  45(10):1232-7  PubMed ID: 23955599   DOI: 10.1038/ng.2731
15925  Takahashi K, Orba Y, Kimura T, Wang L, Kohsaka S, Tsuda M, Tanino M, Nishihara H, Nagashima K, Sawa H, Tanaka S.  Relationship between methyl CpG binding protein 2 and JC viral proteins  Jpn J Infect Dis  2013  66(2):126-32.  PubMed ID: 23514909   DOI: 10.7883/yoken.66.126
15933  Koyama T, Sun B, Tokunaga K, Tatsumi M, Ishizaka Y.  DNA damage enhances integration of HIV-1 into macrophages by overcoming integrase inhibition  Retrovirology  2013  10:21  PubMed ID: 23432899   DOI: 10.1186/1742-4690-10-21
16037  Yaguchi M, Ohashi Y, Tsubota T, Sato A, Koyano KW, Wang N, Miyashita Y.  Characterization of the properties of seven promoters in the motor cortex of rats and monkeys after lentiviral vector-mediated gene transfer  Hum Gene Ther Methods   2013  24(6):333-44  PubMed ID: 23964981   DOI: 10.1089/hgtb.2012.238
16888  Haruta M, Tomita Y, Yuno A, Matsumura K, Ikeda T, Takamatsu K, Haga E, Koba C, Nishimura Y, Senju S.  TAP-deficient human iPS cell-derived myeloid cell lines as unlimited cell source for dendritic cell-like antigen-presenting cells  Gene Ther  2013  504-13  PubMed ID: 22875043   DOI: 10.1038/gt.2012.59
17160  Matsushita N, Matsushita S, Hirakawa S, Higashiyama S.  Doxycycline-dependent inducible and reversible RNA interference mediated by a single lentivirus vector  Biosci Biotechnol Biochem  2013  77(4):776-81  PubMed ID: 23563548   DOI: 10.1271/bbb.120917
7627  Ohue Y, Eikawa S, Okazaki N, Mizote Y, Isobe M, Uenaka A, Fukuda M, Old LJ, Oka M, Nakayama E.  Spontaneous antibody, and CD4 and CD8 T-cell responses against XAGE-1b (GAGED2a) in non-small cell lung cancer patients.  Int. J. Cancer  2012  131:E649-58  PubMed ID: 22109656   DOI: 10.1002/ijc.27359
18593  Watanabe Y, Ibrahim MS, Ellakany HF, Kawashita N, Daidoji T, Takagi T, Yasunaga T, Nakaya T, Ikuta K.  Antigenic analysis of highly pathogenic avian influenza virus H5N1 sublineages co-circulating in Egypt  J Gen Virol  2012  93(Pt 10):2215-2226  PubMed ID: 22791605   DOI: 10.1099/vir.0.044032-0
10938  Ayami Yamaguchi 1, Sae Tanaka, Shiho Yamaguchi, Hirokazu Kuwahara, Chizuko Takamura, Shinobu Imajoh-Ohmi, Daiki D Horikawa, Atsushi Toyoda, Toshiaki Katayama, Kazuharu Arakawa, Asao Fujiyama, Takeo Kubo, Takekazu Kunieda  Two Novel Heat-Soluble Protein Families Abundantly Expressed in an Anhydrobiotic Tardigrade  PLoS One  2012  7(8):e44209  PubMed ID: 22937162   DOI: 10.1371/journal.pone.0044209
15731  Nishimura T, Honda H, Takeichi M.  Planar cell polarity links axes of spatial dynamics in neural-tube closure  Cell  2012  149(5):1084-97  PubMed ID: 22632972   DOI: 10.1016/j.cell.2012.04.021
16569  Ooe H, Chen Q, Kon J, Sasaki K, Miyoshi H, Ichinohe N, Tanimizu N, Mitaka T.  Proliferation of rat small hepatocytes requires follistatin expression  J Cell Physiol  2012  227(6):2363-70  PubMed ID: 21826650   DOI: 10.1002/jcp.22971
16592  Li Y, Mitsuhashi S, Ikejo M, Miura N, Kawamura T, Hamakubo T, Ubukata M.  Relationship between ATM and ribosomal protein S6 revealed by the chemical inhibition of Ser/Thr protein phosphatase type 1  Biosci Biotechnol Biochem  2012  76(3):486-94  PubMed ID: 22451389   DOI: 10.1271/bbb.110774
16631  subota T, Ohashi Y, Tamura K, Miyashita Y.  Optogenetic inhibition of Purkinje cell activity reveals cerebellar control of blood pressure during postural alterations in anesthetized rats  Neuroscience .  2012  210:137-44  PubMed ID: 22441034   DOI: 10.1016/j.neuroscience.2012.03.014
18252  Horibe T, Kohno M, Haramoto M, Ohara K, Kawakami K.  Designed hybrid TPR peptide targeting Hsp90 as a novel anticancer agent  J Transl Med  2011  9:8  PubMed ID: 21235734   DOI: 10.1186/1479-5876-9-8
7710  Sakaguchi T, Irie T, Kuwayama M, Ueno T, Yoshida A, Kawabata R.  Analysis of interaction of Sendai virus V protein and melanoma differentiation-associated gene 5.  Microbiol. Immunol.  2011  55:760-7  PubMed ID: 21851384   DOI: 10.1111/j.1348-0421.2011.00379.x
7914  Jin ZB, Okamoto S, Osakada F, Homma K, Assawachananont J, Hirami Y, Iwata T, Takahashi M.  Modeling retinal degeneration using patient-specific induced pluripotent stem cells.  PLoS ONE  2011  6:e17084  PubMed ID: 21347327   DOI: 10.1371/journal.pone.0017084
7970  Narukawa M, Noga C, Ueno Y, Sato T, Misaka T, Watanabe T.  Evaluation of the bitterness of green tea catechins by a cell-based assay with the human bitter taste receptor hTAS2R39.  Biochem. Biophys. Res. Commun.  2011  405:620-5  PubMed ID: 21272567   DOI: 10.1016/j.bbrc.2011.01.079
12293  Ayako Kataoka, Yui Koga, Ayumi Uesugi, Hidetoshi Tozaki-Saitoh, Makoto Tsuda, Kazuhide Inoue  Involvement of vasodilator-stimulated phosphoprotein in UDP-induced microglial actin aggregation via PKC- and Rho-dependent pathways  Purinergic Signal  2011  7(4):403-11  PubMed ID: 21567128   DOI: 10.1007/s11302-011-9237-8
15723  Sasaki M, Kawahara K, Nishio M, Mimori K, Kogo R, Hamada K, Itoh B, Wang J, Komatsu Y, Yang YR, Hikasa H, Horie Y, Yamashita T, Kamijo T, Zhang Y, Zhu Y, Prives C, Nakano T, Mak TW, Sasaki T, Maehama T, Mori M, Suzuki A.  Regulation of the MDM2-P53 pathway and tumor growth by PICT1 via nucleolar RPL11  Nat Med  2011  17(8):944-51  PubMed ID: 21804542   DOI: 10.1038/nm.2392
8223  Mimasu S, Umezawa N, Sato S, Higuchi T, Umehara T, Yokoyama S.  Structurally designed trans-2-phenylcyclopropylamine derivatives potently inhibit histone demethylase LSD1/KDM1 .  Biochemistry  2010  49:6494-503  PubMed ID: 20568732   DOI: 10.1021/bi100299r
8240  Naoe H, Araki K, Nagano O, Kobayashi Y, Ishizawa J, Chiyoda T, Shimizu T, Yamamura K, Sasaki Y, Saya H, Kuninaka S.  The anaphase-promoting complex/cyclosome activator Cdh1 modulates Rho GTPase by targeting p190 RhoGAP for degradation.  Mol. Cell. Biol.  2010  30:3994-4005  PubMed ID: 20530197   DOI: 10.1128/MCB.01358-09
8251  Shigemura T, Shiohara M, Tanaka M, Takeuchi K, Koike K.  Effect of the mutant microphthalmia-associated transcription factor found in Tietz syndrome on the in vitro development of mast cells.  J. Pediatr. Hematol. Oncol.  2010  32:442-7  PubMed ID: 20485200   DOI: 10.1097/MPH.0b013e3181d9da5d
8531  Yamatoya K, Yoshida K, Ito C, Maekawa M, Yanagida M, Takamori K, Ogawa H, Araki Y, Miyado K, Toyama Y, Toshimori K.  Equatorin: identification and characterization of the epitope of the MN9 antibody in the mouse.  Biol. Reprod.  2009  81:889-97  PubMed ID: 19605790   DOI: 10.1095/biolreprod.109.077438
18454  Seto M, Ohta M, Asaoka Y, Ikenoue T, Tada M, Miyabayashi K, Mohri D, Tanaka Y, Ijichi H, Tateishi K, Kanai F, Kawabe T, Omata M.  Regulation of the hedgehog signaling by the mitogen-activated protein kinase cascade in gastric cancer  Mol Carcinog  2009  48(8):703-12  PubMed ID: 19142899   DOI: 10.1002/mc.20516
11019  Shoudai Furuyama, Yoshinari Uehara, Bo Zhang, Yasuhiko Baba, Satomi Abe, Takahiro Iwamoto, Shin-Ichiro Miura, Keijiro Saku  Genotypic Effect of ABCG1 gene promoter -257T>G polymorphism on coronary artery disease severity in Japanese men  J Atheroscler Thromb  2009  16(3):194-200  PubMed ID: 19556716   DOI: 10.5551/jat.e380
11002  Hiroyuki Oshiumi 1, Yuzuru Suzuki, Misako Matsumoto, Tsukasa Seya  Regulator of complement activation (RCA) gene cluster in Xenopus tropicalis  Immunogenetics  2009  61(5):371-84  PubMed ID: 19319518   DOI: 10.1007/s00251-009-0368-9
4887  Satoh T, Arii J, Suenaga T, Wang J, Kogure A, Uehori J, Arase N, Shiratori I, Tanaka S, Kawaguchi Y, Spear PG, Lanier LL, Arase H.  PILRalpha is a herpes simplex virus-1 entry coreceptor that associates with glycoprotein B.  Cell  2008  132(6):935-44  PubMed ID: 18358807   DOI: 10.1016/j.cell.2008.01.043
9071  Shiori Haga, Norio Yamamoto, Chikako Nakai-Murakami, Yoshiaki Osawa, Kenzo Tokunaga, Tetsutaro Sata, Naoki Yamamoto, Takehiko Sasazuki, Yukihito Ishizaka  Modulation of TNF-alpha-converting Enzyme by the Spike Protein of SARS-CoV and ACE2 Induces TNF-alpha Production and Facilitates Viral Entry  Proc Natl Acad Sci U S A  2008  105 (22), 7809-14  PubMed ID: 18490652   DOI: 10.1073/pnas.0711241105
12783  Ueno K, Hiura M, Suehiro Y, Hazama S, Hirata H, Oka M, Imai K, Dahiya R, Hinoda Y.  Frizzled-7 as a potential therapeutic target in colorectal cancer  Neoplasia  2008  10(7):697-705  PubMed ID: 18592008   DOI: 10.1593/neo.08320
6478  Nakatani S, Mano H, Ryanghyok IM, Shimizu J, Wada M.  Excess magnesium inhibits excess calcium-induced matrix-mineralization and production of matrix gla protein (MGP) by ATDC5 cells.  Biochem Biophys Res Commun  2006  348(3):1157-62  PubMed ID: 16904632   DOI: 10.1016/j.bbrc.2006.07.180


戻る 戻る 理研トップページへ