| 利用者成果(英) |
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17565
Arai Y, Yamanaka I, Okamoto T, Isobe A, Nakai N, Kamimura N, Suzuki T, Daidoji T, Ono T, Nakaya T, Matsumoto K, Okuzaki D, Watanabe Y.
Stimulation of interferon-β responses by aberrant SARS-CoV-2 small viral RNAs acting as retinoic acid-inducible gene-I agonists
iScience
2023
26(1):105742
PubMed ID: 36507221
DOI: 10.1016/j.isci.2022.105742
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17804
Toshiki Takahashi, Jun Shirai, Miyo Matsuda, Sae Nakanaga, Shin Matsushita, Kei Wakita, Mizuki Hayashishita, Rigel Suzuki, Aya Noguchi, Naoto Yokota, and Hiroyuki Kawahara
Protein quality control machinery supports primary ciliogenesis by eliminating GDP-bound Rab8- family GTPases
iScience
2023
DOI: 10.1016/ j.isci.2023.106652
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18094
Nakajima M, Kawahara R, Simizu S.
Cofilin promotes vasculogenic mimicry by regulating the actin cytoskeleton in human breast cancer cells
FEBS Lett
2023
597(8):1114-1124
PubMed ID: 36737242
DOI: 10.1002/1873-3468.14594
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18098
Gohara Y, Tomonobu N, Kinoshita R, Futami J, Audebert L, Chen Y, Komalasari NLGY, Jiang F, Yoshizawa C, Murata H, Yamamoto KI, Watanabe M, Kumon H, Sakaguchi M.
Novel extracellular role of REIC/Dkk-3 protein in PD-L1 regulation in cancer cells
J Mol Med (Berl)
2023
101(4):431-447
PubMed ID: 36869893
DOI: 10.1007/s00109-023-02292-w
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18106
Komalasari NLGY, Tomonobu N, Kinoshita R, Chen Y, Sakaguchi Y, Gohara Y, Jiang F, Yamamoto KI, Murata H, Ruma IMW, Sumardika IW, Zhou J, Yamauchi A, Kuribayashi F, Inoue Y, Toyooka S, Sakaguchi M.
Lysyl oxidase-like 4 exerts an atypical role in breast cancer progression that is dependent on the enzymatic activity that targets the cell-surface annexin A2
Front Oncol
2023
13:1142907
PubMed ID: 37091157
DOI: 10.3389/fonc.2023.1142907
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18139
Hoshino N, Kanadome T, Takasugi T, Itoh M, Kaneko R, Inoue YU, Inoue T, Hirabayashi T, Watanabe M, Matsuda T, Nagai T, Tarusawa E, Yagi T.
Visualization of trans homophilic interaction of clustered protocadherin in neurons
Proc Natl Acad Sci U S A
2023
120(38):e2301003120
PubMed ID: 37695902
DOI: 10.1073/pnas.2301003120
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18171
Kikuchi M, Takase S, Konuma T, Noritsugu K, Sekine S, Ikegami T, Ito A, Umehara T.
GAS41 promotes H2A.Z deposition through recognition of the N terminus of histone H3 by the YEATS domain
Proc Natl Acad Sci U S A
2023
120(43):e2304103120
PubMed ID: 37844223
DOI: 10.1073/pnas.2304103120
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20922
Sasaki M, Tabata K, Kishimoto M, Itakura Y, Kobayashi H, Ariizumi T, Uemura K, Toba S, Kusakabe S, Maruyama Y, Iida S, Nakajima N, Suzuki T, Yoshida S, Nobori H, Sanaki T, Kato T, Shishido T, Hall WW, Orba Y, Sato A, Sawa H.
S-217622, a SARS-CoV-2 main protease inhibitor, decreases viral load and ameliorates COVID-19 severity in hamsters.
Sci Transl Med
2023
15(679):eabq4064
PubMed ID: 36327352
DOI: 10.1126/scitranslmed.abq4064
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20993
Okamoto K, Kamikubo Y, Yamauchi K, Okamoto S, Takahashi M, Ishida Y, Koike M, Ikegaya Y, Sakurai T, Hioki H.
Specific AAV2/PHP.eB-mediated gene transduction of CA2 pyramidal cells via injection into the lateral ventricle.
Sci Rep
2023
13(1):323
PubMed ID: 36609635
DOI: 10.1038/s41598-022-27372-8
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21011
Hiyamizu S, Qiu H, Vuolo L, Stevenson NL, Shak C, Heesom KJ, Hamada Y, Tsurumi Y, Chiba S, Katoh Y, Stephens DJ, Nakayama K.
Multiple interactions of the dynein-2 complex with the IFT-B complex are required for effective IFT.
J Cell Sci
2023
PubMed ID: 36632779
DOI: 10.1242/jcs.260462
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21015
Shoji H, Kitao K, Miyazawa T, Nakagawa S.
Potentially reduced fusogenicity of syncytin-2 in New World monkeys.
FEBS Open Bio
2023
PubMed ID: 36647789
DOI: 10.1002/2211-5463.13555
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21065
Morihiro K, Osumi H, Morita S, Hattori T, Baba M, Harada N, Ohashi R, Okamoto A.
Oncolytic Hairpin DNA Pair: Selective Cytotoxic Inducer through MicroRNA-Triggered DNA Self-Assembly.
J Am Chem Soc
2023
145(1):135-142
PubMed ID: 36538570
DOI: 10.1021/jacs.2c08974
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21076
Sato M, Maishi N, Hida Y, Yanagawa-Matsuda A, Alam MT, Sakakibara-Konishi J, Nam JM, Onodera Y, Konno S, Hida K.
Angiogenic inhibitor pre-administration improves the therapeutic effects of immunotherapy.
Cancer Med
2023
PubMed ID: 36808261
DOI: 10.1002/cam4.5696
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21092
Yoshimoto S, Suzuki T, Otani N, Takahashi D, Toshima K, Dohmae N, Simizu S.
Destabilization of vitelline membrane outer layer protein 1 homolog (VMO1) by C-mannosylation.
FEBS Open Bio
2023
PubMed ID: 36680395
DOI: 10.1002/2211-5463.13561
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21101
Ota A, Morita H, Naganuma T, Miyamoto M, Jojima K, Nojiri K, Matsuda J, Kihara A.
Bifunctional DEGS2 has higher hydroxylase activity toward substrates with very-long-chain fatty acids in the production of phytosphingosine-ceramides.
J Biol Chem
2023
104603
PubMed ID: 36907437
DOI: 10.1016/j.jbc.2023.104603
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17485
Tanikawa S, Ebisu Y, Sedlačík T, Semba S, Nonoyama T, Kurokawa T, Hirota A, Takahashi T, Yamaguchi K, Imajo M, Kato H, Nishimura T, Tanei ZI, Tsuda M, Nemoto T, Gong JP, Tanaka S.
Engineering of an electrically charged hydrogel implanted into a traumatic brain injury model for stepwise neuronal tissue reconstruction
Sci Rep
2023
13(1):2233
PubMed ID: 36788295
DOI: 10.1038/s41598-023-28870-z
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21104
Kawano T, Kashiwagi M, Kanuka M, Chen CK, Yasugaki S, Hatori S, Miyazaki S, Tanaka K, Fujita H, Nakajima T, Yanagisawa M, Nakagawa Y, Hayashi Y.
ER proteostasis regulators cell-non-autonomously control sleep.
Cell Rep
2023
42(3):112267
PubMed ID: 36924492
DOI: 10.1016/j.celrep.2023.112267
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21158
Tao F, Kitamura K, Hanada S, Sugimoto K, Furihata T, Kojima N.
Rapid and Stable Formation Method of Human Astrocyte Spheroid in a High Viscous Methylcellulose Medium and Its Functional Advantages.
Bioengineering (Basel)
2023
10(3)
PubMed ID: 36978740
DOI: 10.3390/bioengineering10030349
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21159
Watanabe T, Narahari A, Bhardwaj E, Kuriyama K, Nishimura M, Izumi T, Fujimuro M, Ohno S.
Conserved cysteine residues in Kaposi's sarcoma herpesvirus ORF34 are necessary for viral production and viral pre-initiation complex formation.
bioRxiv
2023
PubMed ID: 36945456
DOI: 10.1101/2023.03.08.531831
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21179
Noritsugu K, Suzuki T, Dodo K, Ohgane K, Ichikawa Y, Koike K, Morita S, Umehara T, Ogawa K, Sodeoka M, Dohmae N, Yoshida M, Ito A.
Lysine long-chain fatty acylation regulates the TEAD transcription factor.
Cell Rep
2023
112388
PubMed ID: 37060904
DOI: 10.1016/j.celrep.2023.112388
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21219
Jojima K, Kihara A.
Metabolism of sphingadiene and characterization of the sphingadiene-producing enzyme FADS3.
Biochim Biophys Acta Mol Cell Biol Lipids
2023
1868(8):159335
PubMed ID: 37209771
DOI: 10.1016/j.bbalip.2023.159335
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21222
Takahashi T, Shirai J, Matsuda M, Nakanaga S, Matsushita S, Wakita K, Hayashishita M, Suzuki R, Noguchi A, Yokota N, Kawahara H.
Protein quality control machinery supports primary ciliogenesis by eliminating GDP-bound Rab8-family GTPases.
iScience
2023
26(5):106652
PubMed ID: 37182096
DOI: 10.1016/j.isci.2023.106652
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21248
Kasuga Y, Ouda R, Watanabe M, Sun X, Kimura M, Hatakeyama S, Kobayashi KS.
FBXO11 constitutes a major negative regulator of MHC class II through ubiquitin-dependent proteasomal degradation of CIITA.
Proc Natl Acad Sci U S A
2023
120(24):e2218955120
PubMed ID: 37279268
DOI: 10.1073/pnas.2218955120
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21258
Nishi K, Yoshii A, Abell L, Zhou B, Frausto R, Ritterhoff J, McMillen TS, Sweet I, Wang Y, Gao C, Tian R.
Branched-chain keto acids inhibit mitochondrial pyruvate carrier and suppress gluconeogenesis in hepatocytes.
Cell Rep
2023
42(6):112641
PubMed ID: 37310861
DOI: 10.1016/j.celrep.2023.112641
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21261
Hiyamizu S, Qiu H, Tsurumi Y, Hamada Y, Katoh Y, Nakayama K.
Dynein-2-driven intraciliary retrograde trafficking indirectly requires multiple interactions of IFT54 in the IFT-B complex with the dynein-2 complex.
Biol Open
2023
PubMed ID: 37309605
DOI: 10.1242/bio.059976
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21265
Shimohata A, Rai D, Akagi T, Usui S, Ogiwara I, Kaneda M.
The intracellular C-terminal domain of mGluR6 contains ER retention motifs.
Mol Cell Neurosci
2023
103875
PubMed ID: 37352898
DOI: 10.1016/j.mcn.2023.103875
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21270
Yamaguchi S, Kamino M, Hamamura M, Otsuguro KI.
The cytosolic N-terminal region of heterologously-expressed transmembrane channel-like protein 1 (TMC1) can be cleaved in HEK293 cells.
PLoS One
2023
18(6):e0287249
PubMed ID: 37352201
DOI: 10.1371/journal.pone.0287249
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21278
Okada M, Shimizu K, Nakazato H, Yamasaki S, Fujii SI.
Detection of mutant antigen-specific T cell receptors against multiple myeloma for T cell engineering.
Mol Ther Methods Clin Dev
2023
29:541-555
PubMed ID: 37359417
DOI: 10.1016/j.omtm.2023.05.014
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21285
Morishita K, Kondo J, Sakon D, Hayashibara A, Tamura I, Shimizu K, Takamatsu S, Murata K, Kamada Y, Miyoshi E.
Prohaptoglobin is a possible prognostic biomarker for colorectal cancer.
Biochem Biophys Res Commun
2023
672:72-80
PubMed ID: 37343317
DOI: 10.1016/j.bbrc.2023.06.017
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21309
Tanaka Y, Morozumi A, Hirokawa N.
Nodal flow transfers polycystin to determine mouse left-right asymmetry.
Dev Cell
2023
PubMed ID: 37413993
DOI: 10.1016/j.devcel.2023.06.002
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21312
Omata K, Nomura I, Hirata A, Yonezuka Y, Muto H, Kuriki R, Jimbo K, Ogasa K, Kato T.
Isolation and evaluation of erythroid progenitors in the livers of larval, froglet, and adult Xenopus tropicalis.
Biol Open
2023
PubMed ID: 37421150
DOI: 10.1242/bio.059862
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21316
Matsuura-Suzuki E, Toh H, Iwasaki S.
Human-rabbit Hybrid Translation System to Explore the Function of Modified Ribosomes.
Bio Protoc
2023
13(13):e4714
PubMed ID: 37456340
DOI: 10.21769/BioProtoc.4714
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21317
Tokuma H, Sakano D, Tanabe K, Tanizawa Y, Shiraki N, Kume S.
Selective proteasome degradation of C-terminally-truncated human WFS1 in pancreatic beta cells.
FEBS Open Bio
2023
PubMed ID: 37440664
DOI: 10.1002/2211-5463.13674
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21326
Takahashi G, Miyaoka Y.
Large-scale single-cell cloning of genome-edited cultured human cells by On-chip SPiS.
STAR Protoc
2023
4(3):102364
PubMed ID: 37329509
DOI: 10.1016/j.xpro.2023.102364
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21335
Goto M, Nishimura G, Sato H, Yamaguchi Y, Morimoto N, Hashimoto H, Takahashi N.
Pharmacological profile of upacicalcet, a novel positive allosteric modulator of calcium-sensing receptor, in vitro and in vivo.
Eur J Pharmacol
2023
175936
PubMed ID: 37541363
DOI: 10.1016/j.ejphar.2023.175936
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21345
Komuro H, Shinohara S, Fukushima Y, Demachi-Okamura A, Muraoka D, Masago K, Matsui T, Sugita Y, Takahashi Y, Nishida R, Takashima C, Ohki T, Shigematsu Y, Watanabe F, Adachi K, Fukuyama T, Hamana H, Kishi H, Miura D, Tanaka Y, Onoue K, Onoguchi K, Yamashita Y, Stratford R, Clancy T, Yamaguchi R, Kuroda H, Doi K, Iwata H, Matsushita H.
Single-cell sequencing on CD8+ TILs revealed the nature of exhausted T cells recognizing neoantigen and cancer/testis antigen in non-small cell lung cancer.
J Immunother Cancer
2023
11(8)
PubMed ID: 37544663
DOI: 10.1136/jitc-2023-007180
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21353
Kanadome T, Hoshino N, Nagai T, Yagi T, Matsuda T.
Visualization of trans-interactions of a protocadherin-α between processes originating from single neurons.
iScience
2023
26(7):107238
PubMed ID: 37534169
DOI: 10.1016/j.isci.2023.107238
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21367
Lloyd DB, Thompson JF.
Transcriptional modulators affect in vivo protein binding to the low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase promoters.
J Biol Chem
2023
270(43):25812-8
PubMed ID: 7592765
DOI: 10.1074/jbc.270.43.25812
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21373
Suzuki MM, Iijima K, Ogami K, Shinjo K, Murofushi Y, Xie J, Wang X, Kitano Y, Mamiya A, Kibe Y, Nishimura T, Ohka F, Saito R, Sato S, Kobayashi J, Yao R, Miyata K, Kataoka K, Suzuki HI, Kondo Y.
TUG1-mediated R-loop resolution at microsatellite loci as a prerequisite for cancer cell proliferation.
Nat Commun
2023
14(1):4521
PubMed ID: 37607907
DOI: 10.1038/s41467-023-40243-8
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21382
Xu J, Hashino T, Tanaka R, Kawaguchi K, Yoshida H, Kataoka T.
The BCL-2 family protein BCL-RAMBO interacts and cooperates with GRP75 to promote its apoptosis signaling pathway.
Sci Rep
2023
13(1):14041
PubMed ID: 37640805
DOI: 10.1038/s41598-023-41196-0
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21398
Kanao E, Ishida K, Mizuta R, Li Y, Imami K, Tanigawa T, Sasaki Y, Akiyoshi K, Adachi J, Otsuka K, Ishihama Y, Kubo T.
Rapid and Highly Efficient Purification of Extracellular Vesicles Enabled by a TiO2 Hybridized Spongy-like Polymer.
Anal Chem
2023
PubMed ID: 37703188
DOI: 10.1021/acs.analchem.3c03411
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21416
Sogawa A, Komori R, Yanagitani K, Ohfurudono M, Tsuru A, Kadoi K, Kimata Y, Yoshida H, Kohno K.
Signal sequence-triage is activated by translocon obstruction sensed by an ER stress sensor IRE1α.
Cell Struct Funct
2023
PubMed ID: 37766570
DOI: 10.1247/csf.23072
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21472
Takeuchi K, Tabe S, Takahashi K, Aoshima K, Matsuo M, Ueno Y, Furukawa Y, Yamaguchi K, Ohtsuka M, Morinaga S, Miyagi Y, Yamaguchi T, Tanimizu N, Taniguchi H.
Incorporation of human iPSC-derived stromal cells creates a pancreatic cancer organoid with heterogeneous cancer-associated fibroblasts.
Cell Rep
2023
42(11):113420
PubMed ID: 37955987
DOI: 10.1016/j.celrep.2023.113420
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17502
Haraguchi-Suzuki K, Kawabata-Iwakawa R, Suzuki T, Suto T, Takazawa T, Saito S.
Local anesthetic lidocaine induces growth suppression of HeLa cells by decreasing and changing the cellular localization of the proliferation marker Ki-67
Genes Cells
2022
27(11):675-684
PubMed ID: 36074048
DOI: 10.1111/gtc.12983
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17510
Miku Akishino, Yuko Aoki, Hajime Baba, Makio Asakawa, Yoichiro Hama, Susumu Mitsutake
Red algae-derived isofloridoside activates the sweet taste receptor T1R2/T1R3
Food Bioscience
2022
50:102186
DOI: 10.1016/j.fbio.2022.102186
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17529
Tsukida K, Muramatsu SI, Osaka H, Yamagata T, Muramatsu K.
WDR45 variants cause ferrous iron loss due to impaired ferritinophagy associated with nuclear receptor coactivator 4 and WD repeat domain phosphoinositide interacting protein 4 reduction
Brain Commun
2022
4(6):fcac304
PubMed ID: 36751498
DOI: 10.1093/braincomms/fcac304
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17581
Kamiki H, Murakami S, Nishikaze T, Hiono T, Igarashi M, Furuse Y, Matsugo H, Ishida H, Katayama M, Sekine W, Muraki Y, Takahashi M, Takenaka-Uema A, Horimoto T.
Influenza A Virus Agnostic Receptor Tropism Revealed Using a Novel Biological System with Terminal Sialic Acid Knockout Cells
J Virol
2022
96(15):e0041622
PubMed ID: 35862707
DOI: 10.1128/jvi.00416-22
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17616
Yamashita F, Kaieda T, Shimomura T, Kawaguchi M, Lin CY, Johnson MD, Tanaka H, Kiwaki T, Fukushima T, Kataoka H.
Role of the polycystic kidney disease domain in matriptase chaperone activity and localization of hepatocyte growth factor activator inhibitor-1
FEBS J
2022
289(12):3422-3439
PubMed ID: 35020274
DOI: 10.1111/febs.16348
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17620
Saito S, Funayama K, Kato W, Okuda M, Kawamoto M, Matsubara T, Sato T, Sato A, Otsuguro S, Sasaki M, Orba Y, Sawa H, Maenaka K, Shindo K, Imoto M, Arai MA.
Dihydromaniwamycin E, a Heat-Shock Metabolite from Thermotolerant Streptomyces sp. JA74, Exhibiting Antiviral Activity against Influenza and SARS-CoV-2 Viruses
J Nat Prod
2022
85(11):2583-2591
PubMed ID: 36223390
DOI: 10.1021/acs.jnatprod.2c00550
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17651
Wei Z, Shimizu K, Sarii RS, Muthusinghe DS, Lokupathirage SMW, Nio-Kobayashi J, Yoshimatsu K.
Pathological Studies on Hantaan Virus-Infected Mice Simulating Severe Hemorrhagic Fever with Renal Syndrome
Viruses
2022
14(10):2247
PubMed ID: 36298802
DOI: 10.3390/v14102247
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17675
Yamauchi K, Okamoto S, Ishida Y, Konno K, Hoshino K, Furuta T, Takahashi M, Koike M, Isa K, Watanabe M, Isa T, Hioki H.
Fluorochromized tyramide-glucose oxidase as a multiplex fluorescent tyramide signal amplification system for histochemical analysis
Sci Rep
2022
12(1):14807
PubMed ID: 36097273
DOI: 10.1038/s41598-022-19085-9
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17714
Matsumura Y, To TK, Kunieda T, Kohno H, Kakutani T, Kubo T.
Mblk-1/E93, an ecdysone related-transcription factor, targets synaptic plasticity-related genes in the honey bee mushroom bodies
Sci Rep
2022
12(1):21367
PubMed ID: 36494426
DOI: 10.1038/s41598-022-23329-z
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17783
Ohshima T, Yamamoto H, Sakamaki Y, Saito C, Mizushima N.
NCOA4 drives ferritin phase separation to facilitate macroferritinophagy and microferritinophagy
J Cell Biol
2022
221(10):e202203102
PubMed ID: 36066504
DOI: 10.1083/jcb.202203102
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17788
Takeuchi Y, Ushimaru K, Kaneda K, Maruyama C, Ito T, Yamanaka K, Ogasawara Y, Katano H, Kato Y, Dairi T, Hamano Y.
First direct evidence for direct cell-membrane penetrations of polycationic homopoly(amino acid)s produced by bacteria
Commun Biol
2022
5(1):1132
PubMed ID: 36289442
DOI: 10.1038/s42003-022-04110-4
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20207
Tsuji H, Ohmura K, Jin H, Naito R, Arase N, Kohyama M, Suenaga T, Sakakibara S, Kochi Y, Okada Y, Yamamoto K, Kikutani H, Morinobu A, Mimori T, Arase H.
Anti-dsDNA antibodies recognize DNA presented on HLA class II molecules of systemic lupus erythematosus risk alleles.
Arthritis Rheumatol
2022
PubMed ID: 34164946
DOI: 10.1002/art.41897
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20452
Tanaka K, Kandori S, Sakka S, Nitta S, Tanuma K, Shiga M, Nagumo Y, Negoro H, Kojima T, Mathis BJ, Shimazui T, Watanabe M, Sato TA, Miyamoto T, Matsuzaka T, Shimano H, Nishiyama H.
ELOVL2 promotes cancer progression by inhibiting cell apoptosis in renal cell carcinoma.
Oncol Rep
2022
47(2)
PubMed ID: 34841437
DOI: 10.3892/or.2021.8234
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20477
Arase N, Tsuji H, Takamatsu H, Jin H, Konaka H, Hamaguchi Y, Tonomura K, Kotobuki Y, Ueda-Hayakawa I, Matsuoka S, Hirano T, Yorifuji H, Murota H, Ohmura K, Nakashima R, Sato T, Kumanogoh A, Katayama I, Arase H, Fujimoto M.
Cell surface-expressed Ro52/IgG/HLA-DR complex is targeted by autoantibodies in patients with inflammatory myopathies.
J Autoimmun
2022
126:102774
PubMed ID: 34896887
DOI: 10.1016/j.jaut.2021.102774
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20517
Qiu H, Tsurumi Y, Katoh Y, Nakayama K.
Combinations of deletion and missense variations of the dynein-2 DYNC2LI1 subunit found in skeletal ciliopathies cause ciliary defects.
Sci Rep
2022
12(1):31
PubMed ID: 34997029
DOI: 10.1038/s41598-021-03950-0
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20522
Hiraiwa M, Fukasawa K, Iezaki T, Sabit H, Horie T, Tokumura K, Iwahashi S, Murata M, Kobayashi M, Suzuki A, Park G, Kaneda K, Todo T, Hirao A, Nakada M, Hinoi E.
SMURF2 phosphorylation at Thr249 modifies glioma stemness and tumorigenicity by regulating TGF-β receptor stability.
Commun Biol
2022
5(1):22
PubMed ID: 35017630
DOI: 10.1038/s42003-021-02950-0
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20524
Nomura T, Nagao K, Shirai R, Gotoh H, Umeda M, Ono K.
Temperature sensitivity of Notch signaling underlies species-specific developmental plasticity and robustness in amniote brains.
Nat Commun
2022
13(1):96
PubMed ID: 35013223
DOI: 10.1038/s41467-021-27707-5
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16114
Wuputra K, Tsai MH, Kato K, Yang YH, Pan JB, Ku CC, Noguchi M, Kishikawa S, Nakade K, Chen HL, Liu CJ, Nakamura Y, Kuo KK, Lin YC, Chan TF, Wu DC, Hou MF, Huang SK, Lin CS, Yokoyama KK.
Dimethyl sulfoxide stimulates the AhR-Jdp2 axis to control ROS accumulation in mouse embryonic fibroblasts
Cell Biol Toxicol
2022
Mar 15
PubMed ID: 33723743
DOI: 10.1007/s10565-021-09592-2
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20588
Jin H, Kishida K, Arase N, Matsuoka S, Nakai W, Kohyama M, Suenaga T, Yamamoto K, Sasazuki T, Arase H.
Abrogation of self-tolerance by misfolded self-antigens complexed with MHC class II molecules.
Sci Adv
2022
8(9):eabj9867
PubMed ID: 35245125
DOI: 10.1126/sciadv.abj9867
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20597
Murakami Y, Masaki M, Miyazaki S, Oketani R, Hayashi Y, Yanagisawa M, Honjoh S, Kano H.
Spectroscopic second and third harmonic generation microscopy using a femtosecond laser source in the third near-infrared (NIR-III) optical window.
Biomed Opt Express
2022
13(2):694-708
PubMed ID: 35284173
DOI: 10.1364/BOE.446273
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20641
Miyajima Y, Noguchi S, Tanaka Y, Li JR, Nishimura H, Kishima M, Lim J, Furuhata E, Suzuki T, Kasukawa T, Suzuki H.
Prediction of transcription factors associated with DNA demethylation during human cellular development.
Chromosome Res
2022
30(1):109-121
PubMed ID: 35142952
DOI: 10.1007/s10577-022-09685-6
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20659
Chino H, Yamasaki A, Ode KL, Ueda HR, Noda NN, Mizushima N.
Phosphorylation by casein kinase 2 enhances the interaction between ER-phagy receptor TEX264 and ATG8 proteins.
EMBO Rep
2022
e54801
PubMed ID: 35417087
DOI: 10.15252/embr.202254801
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20702
Nashimoto Y, Matsushita F, Dijkstra JM, Nakamura Y, Akiyama H, Hamako J, Morita T, Araki S, Matsui T.
Bitiscetin-3, a Novel C-Type Lectin-like Protein Cloned from the Venom Gland of the Viper Bitis arietans, Induces Platelet Agglutination and Inhibits Binding of Von Willebrand Factor to Collagen.
Toxins (Basel)
2022
14(4)
PubMed ID: 35448845
DOI: 10.3390/toxins14040236
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20704
Kamo H, Kawahara R, Simizu S.
Tyrosinase suppresses vasculogenic mimicry in human melanoma cells.
Oncol Lett
2022
23(5):169
PubMed ID: 35496574
DOI: 10.3892/ol.2022.13289
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20713
Satoda Y, Noguchi T, Fujii T, Taniguchi A, Katoh Y, Nakayama K.
BROMI/TBC1D32 together with CCRK/CDK20 and FAM149B1/JBTS36 contributes to IFT turnaround involving ICK/CILK1.
Mol Biol Cell
2022
mbcE22030089
PubMed ID: 35609210
DOI: 10.1091/mbc.E22-03-0089
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16502
Kamada H, Yasuhira S, Shibazaki M, Amano H, Maesawa C.
DUSP4 Inactivation Leads to Reduced Extracellular Signal‒Regulated Kinase Activity through Upregulation of DUSP6 in Melanoma Cells
J Invest Dermatol
2022
S0022-202X(22)00126-9
PubMed ID: 35189148
DOI: 10.1016/j.jid.2022.02.007
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20729
Ishida Y, Tasaki K, Katoh Y, Nakayama K.
Molecular basis underlying the ciliary defects caused by IFT52 variations found in skeletal ciliopathies.
Mol Biol Cell
2022
mbcE22050188
PubMed ID: 35704471
DOI: 10.1091/mbc.E22-05-0188
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16632
Hada M, Miura H, Tanigawa A, Matoba S, Inoue K, Ogonuki N, Hirose M, Watanabe N, Nakato R, Fujiki K, Hasegawa A, Sakashita A, Okae H, Miura K, Shikata D, Arima T, Shirahige K, Hiratani I, Ogura A.
Highly rigid H3.1/H3.2-H3K9me3 domains set a barrier for cell fate reprogramming in trophoblast stem cells
Genes Dev
2022
36(1-2):84-102
PubMed ID: 34992147
DOI: 10.1101/gad.348782.121
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16658
Sasaki K, Suzuki M, Sonoda T, Schneider-Poetsch T, Ito A, Takagi M, Fujishiro S, Sohtome Y, Dodo K, Umehara T, Aburatani H, Shin-Ya K, Nakao Y, Sodeoka M, Yoshida M.
Visualization of the dynamic interaction between nucleosomal histone H3K9 tri-methylation and HP1α chromodomain in living cells
Cell Chem Biol
2022
S2451-9456(22)00198-2
PubMed ID: 35728598
DOI: 10.1016/j.chembiol.2022.05.006
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16659
Matsuura-Suzuki E, Shimazu T, Takahashi M, Kotoshiba K, Suzuki T, Kashiwagi K, Sohtome Y, Akakabe M, Sodeoka M, Dohmae N, Ito T, Shinkai Y, Iwasaki S.
METTL18-mediated histidine methylation of RPL3 modulates translation elongation for proteostasis maintenance
Elife
2022
11:e72780
PubMed ID: 35674491
DOI: 10.7554/eLife.72780
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20750
Yamada T, Fukasawa K, Horie T, Kadota T, Lyu J, Tokumura K, Ochiai S, Iwahashi S, Suzuki A, Park G, Ueda R, Yamamoto M, Kitao T, Shirahase H, Ochi H, Sato S, Iezaki T, Hinoi E.
The role of CDK8 in mesenchymal stem cells in controlling osteoclastogenesis and bone homeostasis.
Stem Cell Reports
2022
PubMed ID: 35777359
DOI: 10.1016/j.stemcr.2022.06.001
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16732
Zhu Z, Kitano T, Morimatsu M, Tanaka A, Morioka R, Lin X, Orino K, Yoshikawa Y.
BRCA2 C-Terminal RAD51-Binding Domain Confers Resistance to DNA-Damaging Agents
Int J Mol Sci
2022
23(7):4060
PubMed ID: 35409418
DOI: 10.3390/ijms23074060
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16747
Fujii K, Morita S, Mochizuki M, Shibuya-Takahashi R, Fujimori H, Yamaguchi K, Abe J, Yamazaki T, Imai T, Sugamura K, Yasuda J, Satoh K, Sato I, Saito-Koyama R, Fujishima F, Sasano H, Kato Y, Matsuura K, Asada Y, Tamai K.
Establishment of a monoclonal antibody against glycosylated CD271 specific for cancer cells in immunohistochemistry
Cancer Sci . 2022 Mar 28
2022
Mar 28
PubMed ID: 35343032
DOI: 10.1111/cas.15340
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16748
Song W, Isaji T, Nakano M, Liang C, Fukuda T, Gu J.
O-GlcNAcylation regulates β1,4-GlcNAc-branched N-glycan biosynthesis via the OGT/SLC35A3/GnT-IV axis
FASEB J
2022
36(2):e22149
PubMed ID: 34981577
DOI: 10.1096/fj.202101520R
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16749
Kitanishi T, Tashiro M, Kitanishi N, Mizuseki K.
Intersectional, anterograde transsynaptic targeting of neurons receiving monosynaptic inputs from two upstream regions
Commun Biol
2022
5(1):149
PubMed ID: 35190665
DOI: 10.1038/s42003-022-03096-3
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16750
Otsuka K, Sawai-Ogawa M, Kihara A.
Formation of fatty alcohols-components of meibum lipids-by the fatty acyl-CoA reductase FAR2 is essential for dry eye prevention
FASEB J
2022
36(4):e22216
PubMed ID: 35238077
DOI: 10.1096/fj.202101733R
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16765
Takahashi S, Shibutani S, Iwata H.
Nuclear-targeted 4E-BP1 is dephosphorylated, induces nuclear translocation of eIF4E, and alters mRNA translation
Exp Cell Res
2022
418(1):113246
PubMed ID: 35697076
DOI: 10.1016/j.yexcr.2022.113246
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20788
Oishi T, Ito M, Koizumi S, Horikawa M, Yamamoto T, Yamagishi S, Yamasaki T, Sameshima T, Suzuki T, Sugimura H, Namba H, Kurozumi K.
Efficacy of HSV-TK/GCV system suicide gene therapy using SHED expressing modified HSV-TK against lung cancer brain metastases.
Mol Ther Methods Clin Dev
2022
26:253-265
PubMed ID: 35892087
DOI: 10.1016/j.omtm.2022.07.001
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20822
Deai M, Oya R, Saso N, Tanaka A, Uchida I, Miyake Y, Tachihara R, Otsugu M, Mine A, Sato K, Tomura H.
Ethylenediaminetetraacetic acid (EDTA) enhances cAMP production in human TDAG8-expressing cells.
Biochem Biophys Res Commun
2022
626:15-20
PubMed ID: 35964552
DOI: 10.1016/j.bbrc.2022.07.110
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17100
Izumi A, Yamamoto K, Kawaguchi M, Yamashita F, Fukushima T, Kiwaki T, Tanaka H, Yamashita Y, Kataoka H.
Insufficiency of hepatocyte growth factor activator inhibitor-1 confers lymphatic invasion of tongue carcinoma cells
Cancer Sci
2022
113(6):2179-2193
PubMed ID: 35332604
DOI: 10.1111/cas.15346
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20836
Kashio M, Masubuchi S, Tominaga M.
Protein kinase C (PKC)-mediated phosphorylation of TRPM2 Thr738 counteracts the effect of cytosolic Ca2+ and elevates the temperature threshold.
J Physiol
2022
PubMed ID: 36042566
DOI: 10.1113/JP283350
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20845
Zhou Z, Katoh Y, Nakayama K.
CEP19-RABL2-IFT-B axis controls BBSome-mediated ciliary GPCR export.
Mol Biol Cell
2022
PubMed ID: 36074075
DOI: 10.1091/mbc.E22-05-0161
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20857
Nohara T, Ohno Y, Kihara A.
Impaired production of skin barrier lipid acylceramides and abnormal localization of PNPLA1 due to ichthyosis-causing mutations in PNPLA1.
J Dermatol Sci
2022
107(2):89-94
PubMed ID: 35970721
DOI: 10.1016/j.jdermsci.2022.07.008
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20869
Lyu X, Imai S, Yamano T, Hanayama R.
Preventing SARS-CoV-2 Infection Using Anti-spike Nanobody-IFN-β Conjugated Exosomes.
Pharm Res
2022
PubMed ID: 36163411
DOI: 10.1007/s11095-022-03400-0
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20873
Yamamura N, Mikkaichi T, Itokawa KI, Hoshi M, Damme K, Geigner S, Baumhauer C.
Mirogabalin, a novel α2δ ligand, is not a substrate of LAT1, but of PEPT1, PEPT2, OAT1, OAT3, OCT2, MATE1 and MATE2-K.
Xenobiotica
2022
1-42
PubMed ID: 36170033
DOI: 10.1080/00498254.2022.2129517
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20880
Kanadome T, Hayashi K, Seto Y, Eiraku M, Nakajima K, Nagai T, Matsuda T.
Development of intensiometric indicators for visualizing N-cadherin interaction across cells.
Commun Biol
2022
5(1):1065
PubMed ID: 36207396
DOI: 10.1038/s42003-022-04023-2
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20892
Mang D, Mayu K, Toyama T, Yamagishi T, Sato R.
BmGr4 responds to sucrose and glucose and expresses in tachykinin-related peptide-secreting enteroendocrine cells.
Insect Biochem Mol Biol
2022
103858
PubMed ID: 36244651
DOI: 10.1016/j.ibmb.2022.103858
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20906
Nakazato A, Mochizuki M, Shibuya-Takahashi R, Fujimori H, Fujii K, Saijoh S, Morita S, Yamazaki T, Imai T, Sato I, Satoh K, Yamaguchi K, Sugamura K, Yasuda J, Matsuura K, Shojaku H, Asada Y, Tamai K.
RELA is required for CD271 expression and stem-like characteristics in hypopharyngeal cancer.
Sci Rep
2022
12(1):17751
PubMed ID: 36273237
DOI: 10.1038/s41598-022-22736-6
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20912
Kotani N, Nakano T, Kuwahara R.
Host cell membrane proteins located near SARS-CoV-2 spike protein attachment sites are identified using proximity labeling and proteomic analysis.
J Biol Chem
2022
298(11):102500
PubMed ID: 36152751
DOI: 10.1016/j.jbc.2022.102500
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20914
Wang TW, Johmura Y, Suzuki N, Omori S, Migita T, Yamaguchi K, Hatakeyama S, Yamazaki S, Shimizu E, Imoto S, Furukawa Y, Yoshimura A, Nakanishi M.
Blocking PD-L1-PD-1 improves senescence surveillance and ageing phenotypes.
Nature
2022
PubMed ID: 36323784
DOI: 10.1038/s41586-022-05388-4
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20926
Akiyama M, Unoki T, Aoki H, Nishimura A, Shinkai Y, Warabi E, Nishiyama K, Furumoto Y, Anzai N, Akaike T, Nishida M, Kumagai Y.
Cystine-dependent antiporters buffer against excess intracellular reactive sulfur species-induced stress.
Redox Biol
2022
57:102514
PubMed ID: 36279630
DOI: 10.1016/j.redox.2022.102514
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17337
Sekine W, Takenaka-Uema A, Kamiki H, Ishida H, Matsugo H, Murakami S, Horimoto T.
Adaptation of the H7N2 Feline Influenza Virus to Human Respiratory Cell Culture
Viruses
2022
14(5):1091
PubMed ID: 35632832
DOI: 10.3390/v14051091
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20971
Tatsumi A, Hirakochi H, Inoue S, Tanaka Y, Furuno H, Ikeda M, Ishibashi S, Taguchi T, Yamamoto K, Onishi I, Sachs Z, Largaespada DA, Kitagawa M, Kurata M.
Identification of NRAS Downstream Genes with CRISPR Activation Screening.
Biology (Basel)
2022
11(11)
PubMed ID: 36358254
DOI: 10.3390/biology11111551
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20975
Moriyama H, Moriyama M, Ozawa T, Tsuruta D, Hayakawa T.
Differentiation of Human Adipose-Derived Mesenchymal Stromal/Stem Cells into Insulin-Producing Cells with A Single Tet-Off Lentiviral Vector System.
Cell J
2022
24(12):705-714
PubMed ID: 36527342
DOI: 10.22074/cellj.2022.557533.1063
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20998
Ozono T, Kimura Y, Suenaga T, Beck G, Jinno J, Aguirre C, Ikenaka K, Krainc D, Mochizuki H, Arase H.
Extracellular transportation of α-synuclein by HLA class II molecules.
Biochem Biophys Res Commun
2022
644:25-33
PubMed ID: 36621149
DOI: 10.1016/j.bbrc.2022.12.082
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21033
Takahashi TM, Hirano A, Kanda T, Saito VM, Ashitomi H, Tanaka KZ, Yokoshiki Y, Masuda K, Yanagisawa M, Vogt KE, Tokuda T, Sakurai T.
Optogenetic induction of hibernation-like state with modified human Opsin4 in mice.
Cell Rep Methods
2022
2(11):100336
PubMed ID: 36452866
DOI: 10.1016/j.crmeth.2022.100336
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21037
Takahashi M, Kobayashi T, Mizuma H, Yamauchi K, Okamoto S, Okamoto K, Ishida Y, Koike M, Watanabe M, Isa T, Hioki H.
Preferential arborization of dendrites and axons of parvalbumin- and somatostatin-positive GABAergic neurons within subregions of the mouse claustrum.
Neurosci Res
2022
PubMed ID: 36574563
DOI: 10.1016/j.neures.2022.11.008
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17361
Hirose Y, Shindo N, Mori M, Onitsuka S, Isogai H, Hamada R, Hiramoto T, Ochi J, Takahashi D, Ueda T, Caaveiro JMM, Yoshida Y, Ohdo S, Matsunaga N, Toba S, Sasaki M, Orba Y, Sawa H, Sato A, Kawanishi E, Ojida A.
Discovery of Chlorofluoroacetamide-Based Covalent Inhibitors for Severe Acute Respiratory Syndrome Coronavirus 2 3CL Protease
J Med Chem
2022
65(20):13852-13865
PubMed ID: 36229406
DOI: 10.1021/acs.jmedchem.2c01081
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21141
Suenaga T, Mori Y, Suzutani T, Arase H.
Siglec-7 mediates varicella-zoster virus infection by associating with glycoprotein B.
Biochem Biophys Res Commun
2022
607:67-72
PubMed ID: 35367830
DOI: 10.1016/j.bbrc.2022.03.060
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17694
Furuta T, Yamauchi K, Okamoto S, Takahashi M, Kakuta S, Ishida Y, Takenaka A, Yoshida A, Uchiyama Y, Koike M, Isa K, Isa T, Hioki H.
Multi-scale light microscopy/electron microscopy neuronal imaging from brain to synapse with a tissue clearing method, Sca l eSF
iScience
2021
25(1):103601
PubMed ID: 35106459
DOI: 10.1016/j.isci.2021.103601
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12798
Johmura Y, Yamanaka T, Omori S, Wang TW, Sugiura Y, Matsumoto M, Suzuki N, Kumamoto S, Yamaguchi K, Hatakeyama S, Takami T, Yamaguchi R, Shimizu E, Ikeda K, Okahashi N, Mikawa R, Suematsu M, Arita M, Sugimoto M, Nakayama KI, Furukawa Y, Imoto S, Nakanishi M.
Senolysis by glutaminolysis inhibition ameliorates various age-associated disorders
Science
2021
371(6526):265-270
PubMed ID: 33446552
DOI: 10.1126/science.abb5916
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13320
Matsumoto N, Sekiya M, Fujimoto Y, Haga S, Sun-Wada GH, Wada Y, Nakanishi-Matsui M.
Functional complementation of V-ATPase a subunit isoforms in osteoclasts.
J Biochem
2021
169(4):459-466
PubMed ID: 33135054
DOI: 10.1093/jb/mvaa118
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13345
Daifu T, Mikami M, Hiramatsu H, Iwai A, Umeda K, Noura M, Kubota H, Masuda T, Furuichi K, Takasaki S, Noguchi Y, Morita K, Bando T, Hirata M, Kataoka TR, Nakahata T, Kuwahara Y, Iehara T, Hosoi H, Takita J, Sugiyama H, Adachi S, Kamikubo Y.
Suppression of malignant rhabdoid tumors through Chb-M'-mediated RUNX1 inhibition.
Pediatr Blood Cancer
2021
PubMed ID: 33180377
DOI: 10.1002/pbc.28789
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13351
Matsumoto Y, Kishida K, Matsumoto M, Matsuoka S, Kohyama M, Suenaga T, Arase H.
A TCR-like antibody against a proinsulin-containing fusion peptide ameliorates type 1 diabetes in NOD mice.
Biochem Biophys Res Commun
2021
PubMed ID: 33208230
DOI: 10.1016/j.bbrc.2020.11.019
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13463
Shota Someya et al
Tryptophan Metabolism Regulates Proliferative Capacity of Human Pluripotent Stem Cells
iScienc
2021
24
PubMed ID: 33615198
DOI: 10.1016/j.isci.2021.102090
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20008
Umaba R, Kitanishi T, Mizuseki K.
Monosynaptic connection from the subiculum to medial mammillary nucleus neurons projecting to the anterior thalamus and Gudden's ventral tegmental nucleus.
Neurosci Res
2021
PubMed ID: 33476683
DOI: 10.1016/j.neures.2021.01.006
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20053
Takafuji S, Mori T, Nishimura N, Yamamoto N, Uemura S, Nozu K, Terui K, Toki T, Ito E, Muramatsu H, Takahashi Y, Matsuo M, Yamamura T, Iijima K.
Usefulness of functional splicing analysis to confirm precise disease pathogenesis in Diamond-Blackfan anemia caused by intronic variants in RPS19.
Pediatr Hematol Oncol
2021
1-16
PubMed ID: 33622161
DOI: 10.1080/08880018.2021.1887984
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20060
Nishiike Y, Miyazoe D, Togawa R, Yokoyama K, Nakasone K, Miyata M, Kikuchi Y, Kamei Y, Todo T, Ishikawa-Fujiwara T, Ohno K, Usami T, Nagahama Y, Okubo K.
Estrogen receptor 2b is the major determinant of sex-typical mating behavior and sexual preference in medaka.
Curr Biol
2021
PubMed ID: 33639108
DOI: 10.1016/j.cub.2021.01.089
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13513
Takahashi Y, Wake H, Sakaguchi M, Yoshii Y, Teshigawara K, Wang D, Nishibori M.
Histidine-Rich Glycoprotein Stimulates Human Neutrophil Phagocytosis and Prolongs Survival through CLEC1A
J Immunol
2021
206(4):737-750
PubMed ID: 33452125
DOI: 10.4049/jimmunol.2000817
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20067
Aizawa N, Fujimori Y, Nakanishi O, Hayashi T, Goi Y, Kobayashi JI, Fujita T.
Efficacy of the combination of KPR-5714, a novel transient receptor potential melastatin 8 (TRPM8) antagonist, and β3-adrenoceptor agonist or anticholinergic agent on bladder dysfunction in rats with bladder overactivity.
Eur J Pharmacol
2021
173995
PubMed ID: 33675781
DOI: 10.1016/j.ejphar.2021.173995
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20068
Nakamura R, Oyama T, Inokuchi M, Ishikawa S, Hirata M, Kawashima H, Ikeda H, Dobashi Y, Ooi A.
Neural EGFL like 2 expressed in myoepithelial cells and suppressed breast cancer cell migration.
Pathol Int
2021
PubMed ID: 33657249
DOI: 10.1111/pin.13087
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13640
Fujita K, Koide N, Somiya M, Kuroda S, Hinuma S.
A regulatory role of scavenger receptor class B type 1 in endocytosis and lipid droplet formation induced by liposomes containing phosphatidylethanolamine in HEK293T cells
Biochim Biophys Acta Mol Cell Res
2021
1868(1):118859
PubMed ID: 32956759
DOI: 10.1016/j.bbamcr.2020.118859
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20083
Hama K, Fujiwara Y, Hayama T, Ozawa T, Nozawa K, Matsuda K, Hashiguchi Y, Yokoyama K.
Very long-chain fatty acids are accumulated in triacylglycerol and nonesterified forms in colorectal cancer tissues.
Sci Rep
2021
11(1):6163
PubMed ID: 33731797
DOI: 10.1038/s41598-021-85603-w
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20103
McKee HK, Kajiwara C, Yamaguchi T, Ishii Y, Shimizu N, Ohara A, Tateda K.
Clostridioides difficile toxins enhanced the in vitro production of CXC chemokine ligand 2 and tumor necrosis factor-α via Toll-like receptors in macrophages.
J Med Microbiol
2021
70(4)
PubMed ID: 33830910
DOI: 10.1099/jmm.0.001342
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13898
Takuma Kitanishi, Ryoko Umaba, Kenji Mizuseki
Robust information routing by dorsal subiculum neurons
Sci Adv
2021
7(11):eabf1913
PubMed ID: 33692111
DOI: 10.1126/sciadv.abf1913
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13913
Rai D, Akagi T, Shimohata A, Ishii T, Gangi M, Maruyama T, Wada-Kiyama Y, Ogiwara I, Kaneda M.
Involvement of the C-terminal domain in cell surface localization and G-protein coupling of mGluR6
J Neurochem
2021
158(4):837-848
PubMed ID: 33067823
DOI: 10.1111/jnc.15217
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20114
Ojiro I, Nishio H, Yamazaki-Ito T, Nakano S, Ito S, Toyohara Y, Hiramoto T, Terada Y, Ito K.
Trp-Trp acts as a multi-functional blocker for human bitter taste receptors, hTAS2R14, hTAS2R16, hTAS2R43, and hTAS2R46.
Biosci Biotechnol Biochem
2021
PubMed ID: 33844825
DOI: 10.1093/bbb/zbab061
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20138
Nagumo Y, Kandori S, Tanuma K, Nitta S, Chihara I, Shiga M, Hoshi A, Negoro H, Kojima T, Mathis BJ, Funakoshi Y, Nishiyama H.
PLD1 promotes tumor invasion by regulation of MMP-13 expression via NF-κB signaling in bladder cancer.
Cancer Lett
2021
511:15-25
PubMed ID: 33945837
DOI: 10.1016/j.canlet.2021.04.014
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20147
Kariya Y, Oyama M, Suzuki T, Kariya Y.
αvβ3 Integrin induces partial EMT independent of TGF-β signaling.
Commun Biol
2021
4(1):490
PubMed ID: 33883697
DOI: 10.1038/s42003-021-02003-6
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14182
Somiya M, Kuroda S.
Real-Time Luminescence Assay for Cytoplasmic Cargo Delivery of Extracellular Vesicles
Anal Chem
2021
93(13):5612-5620
PubMed ID: 33759512
DOI: 10.1021/acs.analchem.1c00339
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20150
Takeshita M, Suzuki K, Nakazawa M, Kamata H, Ishii M, Oyamada Y, Oshima H, Takeuchi T.
Antigen-driven autoantibody production in lungs of interstitial lung disease with autoimmune disease.
J Autoimmun
2021
121:102661
PubMed ID: 34034155
DOI: 10.1016/j.jaut.2021.102661
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20155
Sahoo PR, Kowada T, Mizukami S.
Long-Term Mg2+ Imaging in Live Cells with a Targetable Fluorescent Probe.
Methods Mol Biol
2021
2274:237-243
PubMed ID: 34050476
DOI: 10.1007/978-1-0716-1258-3_20
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20157
Matsui H, Ito J, Matsui N, Uechi T, Onodera O, Kakita A.
Cytosolic dsDNA of mitochondrial origin induces cytotoxicity and neurodegeneration in cellular and zebrafish models of Parkinson's disease.
Nat Commun
2021
12(1):3101
PubMed ID: 34035300
DOI: 10.1038/s41467-021-23452-x
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20158
Osakabe K, Wada N, Murakami E, Miyashita N, Osakabe Y.
Genome editing in mammalian cells using the CRISPR type I-D nuclease.
Nucleic Acids Res
2021
PubMed ID: 34076237
DOI: 10.1093/nar/gkab348
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20165
Kobayashi JI, Hirasawa H, Fujimori Y, Nakanishi O, Kamada N, Ikeda T, Yamamoto A, Kanbe H.
Identification of N-acyl-N-indanyl-α-phenylglycinamides as selective TRPM8 antagonists designed to mitigate the risk of adverse effects.
Bioorg Med Chem
2021
30:115903
PubMed ID: 33333445
DOI: 10.1016/j.bmc.2020.115903
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14478
Yamanaka D, Shoda M, Matsubara T, Ishibashi KI, Motoi A, Motoi R, Motoi M, Ohno N, Adachi Y.
Open-Label Study of the Influence of Food Containing the Royal Sun Mushroom, Agaricus brasiliensis KA21 (Agaricomycetes), on β-Glucan-Specific Antibody Production in Healthy Human Volunteers
Int J Med Mushrooms
2021
23(2):13-28
PubMed ID: 33639078
DOI: 10.1615/IntJMedMushrooms.2020037471
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20199
Tomita T, Kato M, Mishima T, Matsunaga Y, Sanjo H, Ito KI, Minagawa K, Matsui T, Oikawa H, Takahashi S, Takao T, Iwai N, Mino T, Takeuchi O, Maru Y, Hiratsuka S.
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Nat Commun
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Microfluidics sorting enables the isolation of an intact cellular pair complex of CD8+ T cells and antigen-presenting cells in a cognate antigen recognition-dependent manner.
PLoS One
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Niinae T, Imami K, Sugiyama N, Ishihama Y.
Identification of Endogenous Kinase Substrates by Proximity Labeling Combined with Kinase Perturbation and Phosphorylation Motifs.
Mol Cell Proteomics
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MRC5 cells engineered to express ACE2 serve as a model system for the discovery of antivirals targeting SARS-CoV-2
Sci Rep
2021
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An infectivity-enhancing site on the SARS-CoV-2 spike protein targeted by antibodies
Cell
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Koshizuka T, Kondo H, Kato H, Takahashi K.
Human cytomegalovirus UL42 protein inhibits the degradation of glycoprotein B through inhibition of Nedd4 family ubiquitin E3 ligases.
Microbiol Immunol
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Kaku T, Sugiura K, Entani T, Osabe K, Nagai T.
Enhanced brightness of bacterial luciferase by bioluminescence resonance energy transfer.
Sci Rep
2021
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Shuji Hinuma, Kazuyo Fujita, Shun’ichi Kuroda
Binding of Nanoparticles Harboring Recombinant Large Surface Protein of Hepatitis B Virus to Scavenger Receptor Class B Type 1
Viruses
2021
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Yoshioka K, Obara K, Oikawa S, Uemura K, Yamaguchi A, Fujisawa K, Hanazawa H, Fujiwara M, Endoh T, Suzuki T, Regadera MD, Ito D, Ou G, Xu K, Tanaka Y.
Docosahexaenoic acid inhibits U46619- and prostaglandin F2α-induced pig coronary and basilar artery contractions by inhibiting prostanoid TP receptors.
Eur J Pharmacol
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Identification of small compounds regulating the secretion of extracellular vesicles via a TIM4-affinity ELISA.
Sci Rep
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Orchestration of myeloid-derived suppressor cells in the tumor microenvironment by ubiquitous cellular protein TCTP released by tumor cells
Nat Immunol
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Nakanishi E, Uemura N, Akiyama H, Kinoshita M, Masanori S, Taruno Y, Yamakado H, Matsuzawa SI, Takeda S, Hirabayashi Y, Takahashi R.
Impact of Gba2 on neuronopathic Gaucher's disease and α-synuclein accumulation in medaka (Oryzias latipes).
Mol Brain
2021
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Sakoguchi A, Saito F, Hirayasu K, Shida K, Matsuoka S, Itagaki S, Nakai W, Kohyama M, Suenaga T, Iwanaga S, Horii T, Arase H.
Plasmodium falciparum RIFIN is a novel ligand for inhibitory immune receptor LILRB2.
Biochem Biophys Res Commun
2021
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Nagano C, Takaoka Y, Kamei K, Hamada R, Ichikawa D, Tanaka K, Aoto Y, Ishiko S, Rossanti R, Sakakibara N, Okada E, Horinouchi T, Yamamura T, Tsuji Y, Noguchi Y, Ishimori S, Nagase H, Ninchoji T, Iijima K, Nozu K.
Genotype-Phenotype Correlation in WT1 Exon 8 to 9 Missense Variants.
Kidney Int Rep
2021
6(8):2114-2121
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Fujisawa S, Qiu H, Nozaki S, Chiba S, Katoh Y, Nakayama K.
ARL3 and ARL13B GTPases participate in distinct steps of INPP5E targeting to the ciliary membrane.
Biol Open
2021
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15284
Yoshiko Iizuka, Kinuko Inomata, Risako Nohara, Akimitsu Miyawaki and Yoshifumi Watanabe
Activation of intracellular antioxidant master gene Nrf2 by the extracts of Garcinia subelliptica, Ocimum gratissimum L., and Plectranthus ornatus
International Journal of Herbal Medicine
2021
9(3):54-60
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15524
Fukasawa K, Kadota T, Horie T, Tokumura K, Terada R, Kitaguchi Y, Park G, Ochiai S, Iwahashi S, Okayama Y, Hiraiwa M, Yamada T, Iezaki T, Kaneda K, Yamamoto M, Kitao T, Shirahase H, Hazawa M, Wong RW, Todo T, Hirao A, Hinoi E.
CDK8 maintains stemness and tumorigenicity of glioma stem cells by regulating the c-MYC pathway
Oncogene
2021
40(15):2803-2815
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Noguchi T, Nakamura K, Satoda Y, Katoh Y, Nakayama K.
CCRK/CDK20 regulates ciliary retrograde protein trafficking via interacting with BROMI/TBC1D32.
PLoS One
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Yasumura M, Hagiwara A, Hida Y, Ohtsuka T.
Planar cell polarity protein Vangl2 and its interacting protein Ap2m1 regulate dendritic branching in cortical neurons.
Genes Cells
2021
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Kariya Y, Oyama M, Kariya Y, Hashimoto Y.
Phosphorylated Osteopontin Secreted from Cancer Cells Induces Cancer Cell Motility.
Biomolecules
2021
11(9)
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Yaguchi A, Oshikawa M, Watanabe G, Hiramatsu H, Uchida N, Hara C, Kaneko N, Sawamoto K, Muraoka T, Ajioka I.
Efficient protein incorporation and release by a jigsaw-shaped self-assembling peptide hydrogel for injured brain regeneration.
Nat Commun
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Development of FRET-based indicators for visualizing homophilic trans interaction of a clustered protocadherin.
Sci Rep
2021
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Uemura K, Nobori H, Sato A, Sanaki T, Toba S, Sasaki M, Murai A, Saito-Tarashima N, Minakawa N, Orba Y, Kariwa H, Hall WW, Sawa H, Matsuda A, Maenaka K.
5-Hydroxymethyltubercidin exhibits potent antiviral activity against flaviviruses and coronaviruses, including SARS-CoV-2
iScience
2021
24(10):103120
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Yafei Liu, Noriko Arase, Jun-ichi Kishikawa, Mika Hirose, Songling Li, Asa Tada, Sumiko Matsuoka, Akemi Arakawa, Kanako Akamatsu, Chikako Ono, Hui Jin, Kazuki Kishida, Wataru Nakai, Masako Kohyama, Atsushi Nakagawa, Yoshiaki Yamagishi, Hironori Nakagami, Atsushi Kumanogoh, Yoshiharu Matsuura, Daron M. Standley, Takayuki Kato, Masato Okada, Manabu Fujimoto, Hisashi Arase
The SARS-CoV-2 Delta variant is poised to acquire complete resistance to wild-type spike vaccines
bioRxiv
2021
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Ito F, Kato K, Yanatori I, Murohara T, Toyokuni S.
Ferroptosis-dependent extracellular vesicles from macrophage contribute to asbestos-induced mesothelial carcinogenesis through loading ferritin.
Redox Biol
2021
47:102174
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Ishida H, Murakami S, Kamiki H, Matsugo H, Katayama M, Sekine W, Ohira K, Takenaka-Uema A, Horimoto T.
Construction of an Influenza D Virus with an Eight-Segmented Genome.
Viruses
2021
13(11)
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Masuo K, Chen R, Yogo A, Sugiyama A, Fukuda A, Masui T, Uemoto S, Seno H, Takaishi S.
SNAIL2 contributes to tumorigenicity and chemotherapy resistance in pancreatic cancer by regulating IGFBP2
Cancer Sci
2021
112(12):4987-4999
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Reporter gene assay for membrane fusion of extracellular vesicles
J Extracell Vesicles
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Treatment of Retinoblastoma 1-Intact Hepatocellular Carcinoma With Cyclin-Dependent Kinase 4/6 Inhibitor Combination Therapy
Hepatology
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74(4):1971-1993
PubMed ID: 33931882
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PACAP-PAC1 Signaling Regulates Serotonin 2A Receptor Internalization
PACAP-PAC1 Signaling Regulates Serotonin 2A Receptor Internalization
Front Endocrinol (Lausanne)
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Ishii M, Ando J, Yamazaki S, Toyota T, Ohara K, Furukawa Y, Suehara Y, Nakanishi M, Nakashima K, Ohshima K, Nakauchi H, Ando M.
iPSC-Derived Neoantigen-Specific CTL Therapy for Ewing Sarcoma
Cancer Immunol Res
2021
9(10):1175-1186
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Structural Insight into the Interaction of Sendai Virus C Protein with Alix To Stimulate Viral Budding
J Virol
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Positive feedback regulation between USP15 and ERK2 inhibits osteoarthritis progression through TGF-β/SMAD2 signaling
Arthritis Res Ther
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Pham Tuan Huy Nguyen Pham Quynh Anh Tong Thi Hang Nguyen Hoang Khue Tu Le Minh Thong Nguyen Van Thuan Yen Thi Hai Tran
Home-made in vitro magnetic nanoparticle-based gene delivery system
Science & Technology Development Journal
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Discovery of a transdermally deliverable pentapeptide for activating AdipoR1 to promote hair growth
EMBO Mol Med
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Matsubara D, Yoshimoto T, Soda M, Amano Y, Kihara A, Funaki T, Ito T, Sakuma Y, Shibano T, Endo S, Hagiwara K, Ishikawa S, Fukayama M, Murakami Y, Mano H, Niki T.
Reciprocal expression of trefoil factor-1 and thyroid transcription factor-1 in lung adenocarcinomas
Cancer Sci
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Nature
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Sweet proteins lysozyme and thaumatin are protein-type agonists for the calcium-sensing receptor.
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Different morphologies of human embryonic kidney 293T cells in various types of culture dishes.
Cytotechnology
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Naomi Matsumoto, Reina Matsukawa, Shohei Takahashi, Koshi Kudo, Ge-Hong Sun-Wada, Yoh Wada, Mayumi Nakanishi-Matsui
V-ATPase a3 Isoform Mutations Identified in Osteopetrosis Patients Abolish Its Expression and Disrupt Osteoclast Function
Exp Cell Res
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Hiroshi Suzuki, Yuichi Ozaki, Shigeho Ijiri, Koichiro Gen, Yukinori Kazeto
17β-Hydroxysteroid Dehydrogenase Type 12a Responsible for Testicular 11-ketotestosterone Synthesis in the Japanese Eel, Anguilla Japonica
J Steroid Biochem Mol Biol
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Yusuke Higuchi, Jun-Ichirou Yasunaga, Yu Mitagami, Hirotake Tsukamoto, Kazutaka Nakashima, Koichi Ohshima, Masao Matsuoka
HTLV-1 Induces T Cell Malignancy and Inflammation by Viral Antisense Factor-Mediated Modulation of the Cytokine Signaling
Proc Natl Acad Sci U S A
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Valve Interstitial Cell-Specific Cyclooxygenase-1 Associated With Calcification of Aortic Valves.
Ann. Thorac. Surg
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An ultra-stable cytoplasmic antibody engineered for in vivo applications.
Nat Commun
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Cell Rep
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Upregulation of nuclear factor (erythroid-derived 2)-like 2 protein level in the human colorectal adenocarcinoma cell line DLD-1 by a heterocyclic organobismuth(III) compound: Effect of organobismuth(III) compound on NRF2 signaling.
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Novel Nile tilapia Neu1 sialidases: Molecular cloning and biochemical characterization of the sialidases Neu1a and Neu1b.
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Kampo medicines, Rokumigan, Hachimijiogan, and Goshajinkigan, significantly inhibit glucagon-induced CREB activation.
Heliyon
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The enantiomer pair of 24S- and 24R-hydroxycholesterol differentially alter activity of large-conductance Ca 2+ -dependent K + (slo1 BK) channel
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Polarization-sensitive optical coherence tomography for estimating relative melanin content of autologous induced stem-cell derived retinal pigment epithelium.
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EMBO J
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AirID, a novel proximity biotinylation enzyme, for analysis of protein-protein interactions.
Elife
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Neuroplastinβ-mediated upregulation of solute carrier family 22 member 18 antisense (SLC22A18AS) plays a crucial role in the epithelial-mesenchymal transition, leading to lung cancer cells' enhanced motility.
Biochem Biophys Rep
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Park M, Miyoshi C, Fujiyama T, Kakizaki M, Ikkyu A, Honda T, Choi J, Asano F, Mizuno S, Takahashi S, Yanagisawa M, Funato H.
Loss of the conserved PKA sites of SIK1 and SIK2 increases sleep need.
Sci Rep
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Pathogenic evaluation of synonymous COL4A5 variants in X-linked Alport syndrome using a minigene assay.
Mol Genet Genomic Med
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Asbestos conceives Fe(II)-dependent mutagenic stromal milieu through ceaseless macrophage ferroptosis and β-catenin induction in mesothelium.
Redox Biol
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Male-predominant galanin mediates androgen-dependent aggressive chases in medaka.
Elife
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Glycobiology
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Mol Ther Oncolytics
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Biochim Biophys Acta Mol Cell Biol Lipids
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Quantitative analysis of the effects of nicotinamide phosphoribosyltransferase induction on the rates of NAD+ synthesis and breakdown in mammalian cells using stable isotope-labeling combined with mass spectrometry
PLoS One
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Sci China Life Sci
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Serum Nardilysin, a Surrogate Marker for Epithelial-Mesenchymal Transition, Predicts Prognosis of Intrahepatic Cholangiocarcinoma after Surgical Resection
Clin Cancer Res
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JCI Insight
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Sci Rep
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SPIE BiOS
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Large-scale forward genetics screening identifies Trpa1 as a chemosensor for predator odor-evoked innate fear behaviors.
Nat Commun
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Nat Commun
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Nat Commun
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Biochim Biophys Acta Gene Regul Mech
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Identification of mesothelioma-specific sialylated epitope recognized with monoclonal antibody SKM9-2 in a mucin-like membrane protein HEG1.
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A PB1-K577E Mutation in H9N2 Influenza Virus Increases Polymerase Activity and Pathogenicity in Mice.
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PLoS ONE
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A New in Vitro Model of GDLD by Knocking Out TACSTD2 and Its Paralogous Gene EpCAM in Human Corneal Epithelial Cells.
Transl Vis Sci Technol
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CNPY2 inhibits MYLIP-mediated AR protein degradation in prostate cancer cells.
Oncotarget
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Characterization of H5N1 Influenza Virus Quasispecies with Adaptive Hemagglutinin Mutations from Single-Virus Infections of Human Airway Cells.
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A Split-Luciferase-Based Trimer Formation Assay as a High-throughput Screening Platform for Therapeutics in Alport Syndrome.
Cell Chem Biol
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J Virol
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Anti-tumor efficacy of a novel CLK inhibitor via targeting RNA splicing and MYC-dependent vulnerability
EMBO Mol Med
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A novel fatty acid-binding protein 5-estrogen-related receptor α signaling pathway promotes cell growth and energy metabolism in prostate cancer cells
Oncotarget
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Structural alteration of DNA induced by viral protein R of HIV-1 triggers the DNA damage response
Retrovirology
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MTSS1 Regulation of Actin-Nucleating Formin DAAM1 in Dendritic Filopodia Determines Final Dendritic Configuration of Purkinje Cells
Cell Rep
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Essential Role of the a3 Isoform of V-ATPase in Secretory Lysosome Trafficking via Rab7 Recruitmen
Sci Rep
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Neoplasia
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Virology
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Arthritis Rheumatol
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Blood Adv
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FEBS Open Bio
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An in vitro splicing assay reveals the pathogenicity of a novel intronic variant in ATP6V0A4 for autosomal recessive distal renal tubular acidosis.
BMC Nephrol
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Epigenetics Chromatin
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Critical role of the neural pathway from the intermediate medial mesopallium to the intermediate hyperpallium apicale in filial imprinting of domestic chicks (Gallus gallus domesticus).
Neuroscience
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308:115-24
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Okumura N, Minamiyama R, Ho LT, Kay EP, Kawasaki S, Tourtas T, Schlotzer-Schrehardt U, Kruse FE, Young RD, Quantock AJ, Kinoshita S, Koizumi N.
Involvement of ZEB1 and Snail1 in excessive production of extracellular matrix in Fuchs endothelial corneal dystrophy.
Lab. Invest.
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Ichikawa T, Nakahata S, Fujii M, Iha H, Morishita K.
Loss of NDRG2 enhanced activation of the NF-κB pathway by PTEN and NIK phosphorylation for ATL and other cancer development.
Sci Rep
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5:12841
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The loss of NDRG2 expression improves depressive behavior through increased phosphorylation of GSK3β.
Cell. Signal.
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Tohmonda T, Yoda M, Iwawaki T, Matsumoto M, Nakamura M, Mikoshiba K, Toyama Y, Horiuchi K.
IRE1α/XBP1-mediated branch of the unfolded protein response regulates osteoclastogenesis.
J. Clin. Invest.
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Kimura T, Endo S, Inui M, Saitoh S, Miyake K, Takai T.
Endoplasmic Protein Nogo-B (RTN4-B) Interacts with GRAMD4 and Regulates TLR9-Mediated Innate Immune Responses.
J. Immunol.
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Ito T, Hioki H, Sohn J, Okamoto S, Kaneko T, Iino S, Oliver DL.
Convergence of Lemniscal and Local Excitatory Inputs on Large GABAergic Tectothalamic Neurons.
J. Comp. Neurol.
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Nakazato R, Takarada T, Ikeno S, Nakamura S, Kutsukake T, Hinoi E, Yoneda Y.
Upregulation of Runt-Related Transcription Factor-2 Through CCAAT Enhancer Binding Protein-β Signaling Pathway in Microglial BV-2 Cells Exposed to ATP.
J. Cell. Physiol.
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230:2510-21
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Ebina H, Kanemura Y, Misawa N, Sakuma T, Kobayashi T, Yamamoto T, Koyanagi Y.
A high excision potential of TALENs for integrated DNA of HIV-based lentiviral vector.
PLoS ONE
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10:e0120047
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Masuda K, Chiyoda T, Sugiyama N, Segura-Cabrera A, Kabe Y, Ueki A, Banno K, Suematsu M, Aoki D, Ishihama Y, Saya H, Kuninaka S.
LATS1 and LATS2 phosphorylate CDC26 to modulate assembly of the tetratricopeptide repeat subcomplex of APC/C.
PLoS ONE
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10:e0118662
PubMed ID: 25723520
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Mochimaru Y, Azuma M, Oshima N, Ichijo Y, Satou K, Matsuda K, Asaoka Y, Nishina H, Nakakura T, Mogi C, Sato K, Okajima F, Tomura H.
Extracellular acidification activates ovarian cancer G-protein-coupled receptor 1 and GPR4 homologs of zebra fish.
Biochem. Biophys. Res. Commun.
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457:493-9
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Nakamura R, Oyama T, Tajiri R, Mizokami A, Namiki M, Nakamoto M, Ooi A.
Expression and regulatory effects on cancer cell behavior of NELL1 and NELL2 in human renal cell carcinoma.
Cancer Sci
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106(5):656-64
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9488
Tadahiro Suenaga, Maki Matsumoto, Fuminori Arisawa, Masako Kohyama, Kouyuki Hirayasu, Yasuko Mori, Hisashi Arase
Sialic Acids on Varicella-Zoster Virus Glycoprotein B Are Required for Cell-Cell Fusion
J Biol Chem
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290(32):19833-43
PubMed ID: 26105052
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Bill A, Gutierrez A, Kulkarni S, Kemp C, Bonenfant D, Voshol H, Duvvuri U, Gaither LA.
ANO1/TMEM16A interacts with EGFR and correlates with sensitivity to EGFR-targeting therapy in head and neck cancer
Oncotarget
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6(11):9173-88
PubMed ID: 25823819
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Tanaka S, Tanaka J, Miwa Y, Horikawa DD, Katayama T, Arakawa K, Toyoda A, Kubo T, Kunieda T.
Novel mitochondria-targeted heat-soluble proteins identified in the anhydrobiotic Tardigrade improve osmotic tolerance of human cells
PLoS One
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10(2):e0118272
PubMed ID: 25675104
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Shinmyo Y, Asrafuzzaman Riyadh M, Ahmed G, Bin Naser I, Hossain M, Takebayashi H, Kawasaki H, Ohta K, Tanaka H.
Draxin from neocortical neurons controls the guidance of thalamocortical projections into the neocortex
Nat Commun
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Suzuki Y, Kiyokage E, Sohn J, Hioki H, Toida K.
Structural basis for serotonergic regulation of neural circuits in the mouse olfactory bulb
J Comp Neurol
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523(2):262-80
PubMed ID: 25234191
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Ohishi K, Toume K, Arai MA, Koyano T, Kowithayakorn T, Mizoguchi T, Itoh M, Ishibashi M.
9-Hydroxycanthin-6-one, a β-Carboline Alkaloid from Eurycoma longifolia, Is the First Wnt Signal Inhibitor through Activation of Glycogen Synthase Kinase 3β without Depending on Casein Kinase 1α
J Nat Prod
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DOI: 10.1021/acs.jnatprod.5b00153
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Wakimoto T, Uchida K, Mimura K, Kanagawa T, Mehandjiev TR, Aoshima H, Kokubo K, Mitsuda N, Yoshioka Y, Tsutsumi Y, Kimura T, Yanagihara I.
Hydroxylated fullerene: a potential antiinflammatory and antioxidant agent for preventing mouse preterm birth
Am J Obstet Gynecol
2015
213(5):708.e1-9
PubMed ID: 26196453
DOI: 10.1016/j.ajog.2015.07.017
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Yamanishi M, Narazaki H, Asano T.
Melatonin overcomes resistance to clofarabine in two leukemic cell lines by increased expression of deoxycytidine kinase
Exp Hematol
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43(3):207-14
PubMed ID: 25461250
DOI: 10.1016/j.exphem.2014.11.001
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Konoki K, Suga Y, Fuwa H, Yotsu-Yamashita M, Sasaki M.
Evaluation of gambierol and its analogs for their inhibition of human Kv1.2 and cytotoxicity
Bioorg Med Chem Lett
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PubMed ID: 25556093
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Fujiwara H, Ochi T, Ochi F, Miyazaki Y, Asai H, Narita M, Okamoto S, Mineno J, Kuzushima K, Shiku H, Yasukawa M.
Antileukemia multifunctionality of CD4(+) T cells genetically engineered by HLA class I-restricted and WT1-specific T-cell receptor gene transfer
Leukemia
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29(12):2393-401
PubMed ID: 26104661
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Chiba S, Ikushima H, Ueki H, Yanai H, Kimura Y, Hangai S, Nishio J, Negishi H, Tamura T, Saijo S, Iwakura Y, Taniguchi T.
Recognition of tumor cells by Dectin-1 orchestrates innate immune cells for anti-tumor responses
Elife
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3:e04177
PubMed ID: 25149452
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Suzuki-Nakagawa C, Nishimura M, Tsukamoto T, Aoyama S, Ebihara A, Suzuki F, Nakagawa T.
Participation of the extracellular domain in (pro)renin receptor dimerization.
Biochem. Biophys. Res. Commun.
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Saito K, Sakaguchi M, Iioka H, Matsui M, Nakanishi H, Huh NH, Kondo E.
Coxsackie and adenovirus receptor is a critical regulator for the survival and growth of oral squamous carcinoma cells.
Oncogene
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33(10):1274-86
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Okumura N, Hirano H, Numata R, Nakahara M, Ueno M, Hamuro J, Kinoshita S, Koizumi N.
Cell surface markers of functional phenotypic corneal endothelial cells
Invest Ophthalmol Vis Sci
2014
55(11):7610-8
PubMed ID: 25389199
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Murakami-Tonami Y, Kishida S, Takeuchi I, Katou Y, Maris JM, Ichikawa H, Kondo Y, Sekido Y, Shirahige K, Murakami H, Kadomatsu K.
Inactivation of SMC2 shows a synergistic lethal response in MYCN-amplified neuroblastoma cells
Cell Cycle
2014
13(7):1115-31
PubMed ID: 24553121
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15812
Yamashita H, Ichikawa T, Matsuyama D, Kimura Y, Ueda K, Craig SW, Harada I, Kioka N.
The role of the interaction of the vinculin proline-rich linker region with vinexin α in sensing the stiffness of the extracellular matrix
J Cell Sci
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127(Pt 9):1875-86
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Miyagawa-Yamaguchi A, Kotani N, Honke K.
Expressed glycosylphosphatidylinositol-anchored horseradish peroxidase identifies co-clustering molecules in individual lipid raft domains
PLoS One
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PubMed ID: 24671047
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Lu J, Isaji T, Im S, Fukuda T, Hashii N, Takakura D, Kawasaki N, Gu J.
β-Galactoside α2,6-sialyltranferase 1 promotes transforming growth factor-β-mediated epithelial-mesenchymal transition
J Biol Chem
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289(50):34627-41
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Ishikawa F, Kaneko E, Sugimoto T, Ishijima T, Wakamatsu M, Yuasa A, Sampei R, Mori K, Nose K, Shibanuma M.
A mitochondrial thioredoxin-sensitive mechanism regulates TGF-β-mediated gene expression associated with epithelial-mesenchymal transition
Biochem Biophys Res Commun
2014
443(3):821-7
PubMed ID: 24342608
DOI: 10.1016/j.bbrc.2013.12.050
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Park HY, Toume K, Arai MA, Sadhu SK, Ahmed F, Ishibashi M.
Calotropin: a cardenolide from calotropis gigantea that inhibits Wnt signaling by increasing casein kinase 1α in colon cancer cells
Chembiochem
2014
15(6):872-8.
PubMed ID: 24644251
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Takano M, Kanoh A, Amako K, Otani M, Sano K, Kanazawa-Hamada M, Matsuyama S.
Nuclear localization of bradykinin B(2) receptors reflects binding to the nuclear envelope protein lamin C
Eur J Pharmacol
2014
723:507-14
PubMed ID: 24211782
DOI: 10.1016/j.ejphar.2013.09.054
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Goudarzi H, Hida Y, Takano H, Teramae H, Iizasa H, Hamada J.
Hypoxia affects in vitro growth of newly established cell lines from patients with malignant pleural mesothelioma
Biomed Res
2013
34(1):13-21
PubMed ID: 23428976
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18597
Akimoto AM, Takarada T, Maeda M.
Preparation of cell-culturing glass surfaces that release branched polyethyleneimine triggered by thiol-disulfide exchange
Colloids Surf B Biointerfaces
2013
103:360-5
PubMed ID: 23261556
DOI: 10.1016/j.colsurfb.2012.10.031
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6082
Ohnishi H, Sasaki H, Nakamura Y, Kato S, Ando K, Narimatsu H, Tachibana K.
Regulation of cell shape and adhesion by CD34
Cell Adh Migr
2013
7(5):426-33
PubMed ID: 24036614
DOI: 10.4161/cam.25957
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15792
Kon A, Shih LY, Minamino M, Sanada M, Shiraishi Y, Nagata Y, Yoshida K, Okuno Y, Bando M, Nakato R, Ishikawa S, Sato-Otsubo A, Nagae G, Nishimoto A, Haferlach C, Nowak D, Sato Y, Alpermann T, Nagasaki M, Shimamura T, Tanaka H, Chiba K, Yamamoto R, Yamaguchi T, Otsu M, Obara N, Sakata-Yanagimoto M, Nakamaki T, Ishiyama K, Nolte F, Hofmann WK, Miyawaki S, Chiba S, Mori H, Nakauchi H, Koeffler HP, Aburatani H, Haferlach T, Shirahige K, Miyano S, Ogawa S.
Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms
Nat Genet
2013
45(10):1232-7
PubMed ID: 23955599
DOI: 10.1038/ng.2731
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15925
Takahashi K, Orba Y, Kimura T, Wang L, Kohsaka S, Tsuda M, Tanino M, Nishihara H, Nagashima K, Sawa H, Tanaka S.
Relationship between methyl CpG binding protein 2 and JC viral proteins
Jpn J Infect Dis
2013
66(2):126-32.
PubMed ID: 23514909
DOI: 10.7883/yoken.66.126
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15933
Koyama T, Sun B, Tokunaga K, Tatsumi M, Ishizaka Y.
DNA damage enhances integration of HIV-1 into macrophages by overcoming integrase inhibition
Retrovirology
2013
10:21
PubMed ID: 23432899
DOI: 10.1186/1742-4690-10-21
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16037
Yaguchi M, Ohashi Y, Tsubota T, Sato A, Koyano KW, Wang N, Miyashita Y.
Characterization of the properties of seven promoters in the motor cortex of rats and monkeys after lentiviral vector-mediated gene transfer
Hum Gene Ther Methods
2013
24(6):333-44
PubMed ID: 23964981
DOI: 10.1089/hgtb.2012.238
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16888
Haruta M, Tomita Y, Yuno A, Matsumura K, Ikeda T, Takamatsu K, Haga E, Koba C, Nishimura Y, Senju S.
TAP-deficient human iPS cell-derived myeloid cell lines as unlimited cell source for dendritic cell-like antigen-presenting cells
Gene Ther
2013
504-13
PubMed ID: 22875043
DOI: 10.1038/gt.2012.59
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17160
Matsushita N, Matsushita S, Hirakawa S, Higashiyama S.
Doxycycline-dependent inducible and reversible RNA interference mediated by a single lentivirus vector
Biosci Biotechnol Biochem
2013
77(4):776-81
PubMed ID: 23563548
DOI: 10.1271/bbb.120917
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7627
Ohue Y, Eikawa S, Okazaki N, Mizote Y, Isobe M, Uenaka A, Fukuda M, Old LJ, Oka M, Nakayama E.
Spontaneous antibody, and CD4 and CD8 T-cell responses against XAGE-1b (GAGED2a) in non-small cell lung cancer patients.
Int. J. Cancer
2012
131:E649-58
PubMed ID: 22109656
DOI: 10.1002/ijc.27359
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18593
Watanabe Y, Ibrahim MS, Ellakany HF, Kawashita N, Daidoji T, Takagi T, Yasunaga T, Nakaya T, Ikuta K.
Antigenic analysis of highly pathogenic avian influenza virus H5N1 sublineages co-circulating in Egypt
J Gen Virol
2012
93(Pt 10):2215-2226
PubMed ID: 22791605
DOI: 10.1099/vir.0.044032-0
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10938
Ayami Yamaguchi 1, Sae Tanaka, Shiho Yamaguchi, Hirokazu Kuwahara, Chizuko Takamura, Shinobu Imajoh-Ohmi, Daiki D Horikawa, Atsushi Toyoda, Toshiaki Katayama, Kazuharu Arakawa, Asao Fujiyama, Takeo Kubo, Takekazu Kunieda
Two Novel Heat-Soluble Protein Families Abundantly Expressed in an Anhydrobiotic Tardigrade
PLoS One
2012
7(8):e44209
PubMed ID: 22937162
DOI: 10.1371/journal.pone.0044209
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15731
Nishimura T, Honda H, Takeichi M.
Planar cell polarity links axes of spatial dynamics in neural-tube closure
Cell
2012
149(5):1084-97
PubMed ID: 22632972
DOI: 10.1016/j.cell.2012.04.021
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16569
Ooe H, Chen Q, Kon J, Sasaki K, Miyoshi H, Ichinohe N, Tanimizu N, Mitaka T.
Proliferation of rat small hepatocytes requires follistatin expression
J Cell Physiol
2012
227(6):2363-70
PubMed ID: 21826650
DOI: 10.1002/jcp.22971
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16592
Li Y, Mitsuhashi S, Ikejo M, Miura N, Kawamura T, Hamakubo T, Ubukata M.
Relationship between ATM and ribosomal protein S6 revealed by the chemical inhibition of Ser/Thr protein phosphatase type 1
Biosci Biotechnol Biochem
2012
76(3):486-94
PubMed ID: 22451389
DOI: 10.1271/bbb.110774
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16631
subota T, Ohashi Y, Tamura K, Miyashita Y.
Optogenetic inhibition of Purkinje cell activity reveals cerebellar control of blood pressure during postural alterations in anesthetized rats
Neuroscience .
2012
210:137-44
PubMed ID: 22441034
DOI: 10.1016/j.neuroscience.2012.03.014
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18252
Horibe T, Kohno M, Haramoto M, Ohara K, Kawakami K.
Designed hybrid TPR peptide targeting Hsp90 as a novel anticancer agent
J Transl Med
2011
9:8
PubMed ID: 21235734
DOI: 10.1186/1479-5876-9-8
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7710
Sakaguchi T, Irie T, Kuwayama M, Ueno T, Yoshida A, Kawabata R.
Analysis of interaction of Sendai virus V protein and melanoma differentiation-associated gene 5.
Microbiol. Immunol.
2011
55:760-7
PubMed ID: 21851384
DOI: 10.1111/j.1348-0421.2011.00379.x
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7914
Jin ZB, Okamoto S, Osakada F, Homma K, Assawachananont J, Hirami Y, Iwata T, Takahashi M.
Modeling retinal degeneration using patient-specific induced pluripotent stem cells.
PLoS ONE
2011
6:e17084
PubMed ID: 21347327
DOI: 10.1371/journal.pone.0017084
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7970
Narukawa M, Noga C, Ueno Y, Sato T, Misaka T, Watanabe T.
Evaluation of the bitterness of green tea catechins by a cell-based assay with the human bitter taste receptor hTAS2R39.
Biochem. Biophys. Res. Commun.
2011
405:620-5
PubMed ID: 21272567
DOI: 10.1016/j.bbrc.2011.01.079
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12293
Ayako Kataoka, Yui Koga, Ayumi Uesugi, Hidetoshi Tozaki-Saitoh, Makoto Tsuda, Kazuhide Inoue
Involvement of vasodilator-stimulated phosphoprotein in UDP-induced microglial actin aggregation via PKC- and Rho-dependent pathways
Purinergic Signal
2011
7(4):403-11
PubMed ID: 21567128
DOI: 10.1007/s11302-011-9237-8
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15723
Sasaki M, Kawahara K, Nishio M, Mimori K, Kogo R, Hamada K, Itoh B, Wang J, Komatsu Y, Yang YR, Hikasa H, Horie Y, Yamashita T, Kamijo T, Zhang Y, Zhu Y, Prives C, Nakano T, Mak TW, Sasaki T, Maehama T, Mori M, Suzuki A.
Regulation of the MDM2-P53 pathway and tumor growth by PICT1 via nucleolar RPL11
Nat Med
2011
17(8):944-51
PubMed ID: 21804542
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8223
Mimasu S, Umezawa N, Sato S, Higuchi T, Umehara T, Yokoyama S.
Structurally designed trans-2-phenylcyclopropylamine derivatives potently inhibit histone demethylase LSD1/KDM1 .
Biochemistry
2010
49:6494-503
PubMed ID: 20568732
DOI: 10.1021/bi100299r
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8240
Naoe H, Araki K, Nagano O, Kobayashi Y, Ishizawa J, Chiyoda T, Shimizu T, Yamamura K, Sasaki Y, Saya H, Kuninaka S.
The anaphase-promoting complex/cyclosome activator Cdh1 modulates Rho GTPase by targeting p190 RhoGAP for degradation.
Mol. Cell. Biol.
2010
30:3994-4005
PubMed ID: 20530197
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Shigemura T, Shiohara M, Tanaka M, Takeuchi K, Koike K.
Effect of the mutant microphthalmia-associated transcription factor found in Tietz syndrome on the in vitro development of mast cells.
J. Pediatr. Hematol. Oncol.
2010
32:442-7
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Yamatoya K, Yoshida K, Ito C, Maekawa M, Yanagida M, Takamori K, Ogawa H, Araki Y, Miyado K, Toyama Y, Toshimori K.
Equatorin: identification and characterization of the epitope of the MN9 antibody in the mouse.
Biol. Reprod.
2009
81:889-97
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Seto M, Ohta M, Asaoka Y, Ikenoue T, Tada M, Miyabayashi K, Mohri D, Tanaka Y, Ijichi H, Tateishi K, Kanai F, Kawabe T, Omata M.
Regulation of the hedgehog signaling by the mitogen-activated protein kinase cascade in gastric cancer
Mol Carcinog
2009
48(8):703-12
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11019
Shoudai Furuyama, Yoshinari Uehara, Bo Zhang, Yasuhiko Baba, Satomi Abe, Takahiro Iwamoto, Shin-Ichiro Miura, Keijiro Saku
Genotypic Effect of ABCG1 gene promoter -257T>G polymorphism on coronary artery disease severity in Japanese men
J Atheroscler Thromb
2009
16(3):194-200
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11002
Hiroyuki Oshiumi 1, Yuzuru Suzuki, Misako Matsumoto, Tsukasa Seya
Regulator of complement activation (RCA) gene cluster in Xenopus tropicalis
Immunogenetics
2009
61(5):371-84
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Satoh T, Arii J, Suenaga T, Wang J, Kogure A, Uehori J, Arase N, Shiratori I, Tanaka S, Kawaguchi Y, Spear PG, Lanier LL, Arase H.
PILRalpha is a herpes simplex virus-1 entry coreceptor that associates with glycoprotein B.
Cell
2008
132(6):935-44
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9071
Shiori Haga, Norio Yamamoto, Chikako Nakai-Murakami, Yoshiaki Osawa, Kenzo Tokunaga, Tetsutaro Sata, Naoki Yamamoto, Takehiko Sasazuki, Yukihito Ishizaka
Modulation of TNF-alpha-converting Enzyme by the Spike Protein of SARS-CoV and ACE2 Induces TNF-alpha Production and Facilitates Viral Entry
Proc Natl Acad Sci U S A
2008
105 (22), 7809-14
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Ueno K, Hiura M, Suehiro Y, Hazama S, Hirata H, Oka M, Imai K, Dahiya R, Hinoda Y.
Frizzled-7 as a potential therapeutic target in colorectal cancer
Neoplasia
2008
10(7):697-705
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6478
Nakatani S, Mano H, Ryanghyok IM, Shimizu J, Wada M.
Excess magnesium inhibits excess calcium-induced matrix-mineralization and production of matrix gla protein (MGP) by ATDC5 cells.
Biochem Biophys Res Commun
2006
348(3):1157-62
PubMed ID: 16904632
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