| 利用者成果(英) |
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20207
Tsuji H, Ohmura K, Jin H, Naito R, Arase N, Kohyama M, Suenaga T, Sakakibara S, Kochi Y, Okada Y, Yamamoto K, Kikutani H, Morinobu A, Mimori T, Arase H.
Anti-dsDNA antibodies recognize DNA presented on HLA class II molecules of systemic lupus erythematosus risk alleles.
Arthritis Rheumatol
2022
PubMed ID: 34164946
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20452
Tanaka K, Kandori S, Sakka S, Nitta S, Tanuma K, Shiga M, Nagumo Y, Negoro H, Kojima T, Mathis BJ, Shimazui T, Watanabe M, Sato TA, Miyamoto T, Matsuzaka T, Shimano H, Nishiyama H.
ELOVL2 promotes cancer progression by inhibiting cell apoptosis in renal cell carcinoma.
Oncol Rep
2022
47(2)
PubMed ID: 34841437
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20477
Arase N, Tsuji H, Takamatsu H, Jin H, Konaka H, Hamaguchi Y, Tonomura K, Kotobuki Y, Ueda-Hayakawa I, Matsuoka S, Hirano T, Yorifuji H, Murota H, Ohmura K, Nakashima R, Sato T, Kumanogoh A, Katayama I, Arase H, Fujimoto M.
Cell surface-expressed Ro52/IgG/HLA-DR complex is targeted by autoantibodies in patients with inflammatory myopathies.
J Autoimmun
2022
126:102774
PubMed ID: 34896887
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20517
Qiu H, Tsurumi Y, Katoh Y, Nakayama K.
Combinations of deletion and missense variations of the dynein-2 DYNC2LI1 subunit found in skeletal ciliopathies cause ciliary defects.
Sci Rep
2022
12(1):31
PubMed ID: 34997029
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20522
Hiraiwa M, Fukasawa K, Iezaki T, Sabit H, Horie T, Tokumura K, Iwahashi S, Murata M, Kobayashi M, Suzuki A, Park G, Kaneda K, Todo T, Hirao A, Nakada M, Hinoi E.
SMURF2 phosphorylation at Thr249 modifies glioma stemness and tumorigenicity by regulating TGF-β receptor stability.
Commun Biol
2022
5(1):22
PubMed ID: 35017630
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20524
Nomura T, Nagao K, Shirai R, Gotoh H, Umeda M, Ono K.
Temperature sensitivity of Notch signaling underlies species-specific developmental plasticity and robustness in amniote brains.
Nat Commun
2022
13(1):96
PubMed ID: 35013223
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16114
Wuputra K, Tsai MH, Kato K, Yang YH, Pan JB, Ku CC, Noguchi M, Kishikawa S, Nakade K, Chen HL, Liu CJ, Nakamura Y, Kuo KK, Lin YC, Chan TF, Wu DC, Hou MF, Huang SK, Lin CS, Yokoyama KK.
Dimethyl sulfoxide stimulates the AhR-Jdp2 axis to control ROS accumulation in mouse embryonic fibroblasts
Cell Biol Toxicol
2022
Mar 15
PubMed ID: 33723743
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20588
Jin H, Kishida K, Arase N, Matsuoka S, Nakai W, Kohyama M, Suenaga T, Yamamoto K, Sasazuki T, Arase H.
Abrogation of self-tolerance by misfolded self-antigens complexed with MHC class II molecules.
Sci Adv
2022
8(9):eabj9867
PubMed ID: 35245125
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20597
Murakami Y, Masaki M, Miyazaki S, Oketani R, Hayashi Y, Yanagisawa M, Honjoh S, Kano H.
Spectroscopic second and third harmonic generation microscopy using a femtosecond laser source in the third near-infrared (NIR-III) optical window.
Biomed Opt Express
2022
13(2):694-708
PubMed ID: 35284173
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20641
Miyajima Y, Noguchi S, Tanaka Y, Li JR, Nishimura H, Kishima M, Lim J, Furuhata E, Suzuki T, Kasukawa T, Suzuki H.
Prediction of transcription factors associated with DNA demethylation during human cellular development.
Chromosome Res
2022
30(1):109-121
PubMed ID: 35142952
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20659
Chino H, Yamasaki A, Ode KL, Ueda HR, Noda NN, Mizushima N.
Phosphorylation by casein kinase 2 enhances the interaction between ER-phagy receptor TEX264 and ATG8 proteins.
EMBO Rep
2022
e54801
PubMed ID: 35417087
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20702
Nashimoto Y, Matsushita F, Dijkstra JM, Nakamura Y, Akiyama H, Hamako J, Morita T, Araki S, Matsui T.
Bitiscetin-3, a Novel C-Type Lectin-like Protein Cloned from the Venom Gland of the Viper Bitis arietans, Induces Platelet Agglutination and Inhibits Binding of Von Willebrand Factor to Collagen.
Toxins (Basel)
2022
14(4)
PubMed ID: 35448845
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20713
Satoda Y, Noguchi T, Fujii T, Taniguchi A, Katoh Y, Nakayama K.
BROMI/TBC1D32 together with CCRK/CDK20 and FAM149B1/JBTS36 contributes to IFT turnaround involving ICK/CILK1.
Mol Biol Cell
2022
mbcE22030089
PubMed ID: 35609210
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16502
Kamada H, Yasuhira S, Shibazaki M, Amano H, Maesawa C.
DUSP4 Inactivation Leads to Reduced Extracellular Signal‒Regulated Kinase Activity through Upregulation of DUSP6 in Melanoma Cells
J Invest Dermatol
2022
S0022-202X(22)00126-9
PubMed ID: 35189148
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20729
Ishida Y, Tasaki K, Katoh Y, Nakayama K.
Molecular basis underlying the ciliary defects caused by IFT52 variations found in skeletal ciliopathies.
Mol Biol Cell
2022
mbcE22050188
PubMed ID: 35704471
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16632
Hada M, Miura H, Tanigawa A, Matoba S, Inoue K, Ogonuki N, Hirose M, Watanabe N, Nakato R, Fujiki K, Hasegawa A, Sakashita A, Okae H, Miura K, Shikata D, Arima T, Shirahige K, Hiratani I, Ogura A.
Highly rigid H3.1/H3.2-H3K9me3 domains set a barrier for cell fate reprogramming in trophoblast stem cells
Genes Dev
2022
36(1-2):84-102
PubMed ID: 34992147
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16658
Sasaki K, Suzuki M, Sonoda T, Schneider-Poetsch T, Ito A, Takagi M, Fujishiro S, Sohtome Y, Dodo K, Umehara T, Aburatani H, Shin-Ya K, Nakao Y, Sodeoka M, Yoshida M.
Visualization of the dynamic interaction between nucleosomal histone H3K9 tri-methylation and HP1α chromodomain in living cells
Cell Chem Biol
2022
S2451-9456(22)00198-2
PubMed ID: 35728598
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16659
Matsuura-Suzuki E, Shimazu T, Takahashi M, Kotoshiba K, Suzuki T, Kashiwagi K, Sohtome Y, Akakabe M, Sodeoka M, Dohmae N, Ito T, Shinkai Y, Iwasaki S.
METTL18-mediated histidine methylation of RPL3 modulates translation elongation for proteostasis maintenance
Elife
2022
11:e72780
PubMed ID: 35674491
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20750
Yamada T, Fukasawa K, Horie T, Kadota T, Lyu J, Tokumura K, Ochiai S, Iwahashi S, Suzuki A, Park G, Ueda R, Yamamoto M, Kitao T, Shirahase H, Ochi H, Sato S, Iezaki T, Hinoi E.
The role of CDK8 in mesenchymal stem cells in controlling osteoclastogenesis and bone homeostasis.
Stem Cell Reports
2022
PubMed ID: 35777359
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16732
Zhu Z, Kitano T, Morimatsu M, Tanaka A, Morioka R, Lin X, Orino K, Yoshikawa Y.
BRCA2 C-Terminal RAD51-Binding Domain Confers Resistance to DNA-Damaging Agents
Int J Mol Sci
2022
23(7):4060
PubMed ID: 35409418
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16747
Fujii K, Morita S, Mochizuki M, Shibuya-Takahashi R, Fujimori H, Yamaguchi K, Abe J, Yamazaki T, Imai T, Sugamura K, Yasuda J, Satoh K, Sato I, Saito-Koyama R, Fujishima F, Sasano H, Kato Y, Matsuura K, Asada Y, Tamai K.
Establishment of a monoclonal antibody against glycosylated CD271 specific for cancer cells in immunohistochemistry
Cancer Sci . 2022 Mar 28
2022
Mar 28
PubMed ID: 35343032
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16748
Song W, Isaji T, Nakano M, Liang C, Fukuda T, Gu J.
O-GlcNAcylation regulates β1,4-GlcNAc-branched N-glycan biosynthesis via the OGT/SLC35A3/GnT-IV axis
FASEB J
2022
36(2):e22149
PubMed ID: 34981577
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16749
Kitanishi T, Tashiro M, Kitanishi N, Mizuseki K.
Intersectional, anterograde transsynaptic targeting of neurons receiving monosynaptic inputs from two upstream regions
Commun Biol
2022
5(1):149
PubMed ID: 35190665
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16750
Otsuka K, Sawai-Ogawa M, Kihara A.
Formation of fatty alcohols-components of meibum lipids-by the fatty acyl-CoA reductase FAR2 is essential for dry eye prevention
FASEB J
2022
36(4):e22216
PubMed ID: 35238077
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16751
Tomoya Oishi, Masahiko Ito, Shinichiro Koizumi, Makoto Horikawa, Taisuke Yamamoto, Satoru Yamagishi, Tomohiro Yamasaki, Tetsuro Sameshima, Tetsuro Suzuki, Haruhiko Sugimura, Hiroki Namba, Kazuhiko Kurozumi
Efficacy of HSV-TK/GCV system suicide gene therapy using stem cells from human exfoliated deciduous teeth expressing modified HSV-TK against brain metastasis of non-small-cell lung cancer
Molecular Therapy - Methods & Clinical Development
2022
|
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16765
Takahashi S, Shibutani S, Iwata H.
Nuclear-targeted 4E-BP1 is dephosphorylated, induces nuclear translocation of eIF4E, and alters mRNA translation
Exp Cell Res
2022
418(1):113246
PubMed ID: 35697076
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20788
Oishi T, Ito M, Koizumi S, Horikawa M, Yamamoto T, Yamagishi S, Yamasaki T, Sameshima T, Suzuki T, Sugimura H, Namba H, Kurozumi K.
Efficacy of HSV-TK/GCV system suicide gene therapy using SHED expressing modified HSV-TK against lung cancer brain metastases.
Mol Ther Methods Clin Dev
2022
26:253-265
PubMed ID: 35892087
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20822
Deai M, Oya R, Saso N, Tanaka A, Uchida I, Miyake Y, Tachihara R, Otsugu M, Mine A, Sato K, Tomura H.
Ethylenediaminetetraacetic acid (EDTA) enhances cAMP production in human TDAG8-expressing cells.
Biochem Biophys Res Commun
2022
626:15-20
PubMed ID: 35964552
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17100
Izumi A, Yamamoto K, Kawaguchi M, Yamashita F, Fukushima T, Kiwaki T, Tanaka H, Yamashita Y, Kataoka H.
Insufficiency of hepatocyte growth factor activator inhibitor-1 confers lymphatic invasion of tongue carcinoma cells
Cancer Sci
2022
113(6):2179-2193
PubMed ID: 35332604
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20836
Kashio M, Masubuchi S, Tominaga M.
Protein kinase C (PKC)-mediated phosphorylation of TRPM2 Thr738 counteracts the effect of cytosolic Ca2+ and elevates the temperature threshold.
J Physiol
2022
PubMed ID: 36042566
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20845
Zhou Z, Katoh Y, Nakayama K.
CEP19-RABL2-IFT-B axis controls BBSome-mediated ciliary GPCR export.
Mol Biol Cell
2022
PubMed ID: 36074075
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20857
Nohara T, Ohno Y, Kihara A.
Impaired production of skin barrier lipid acylceramides and abnormal localization of PNPLA1 due to ichthyosis-causing mutations in PNPLA1.
J Dermatol Sci
2022
107(2):89-94
PubMed ID: 35970721
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20869
Lyu X, Imai S, Yamano T, Hanayama R.
Preventing SARS-CoV-2 Infection Using Anti-spike Nanobody-IFN-β Conjugated Exosomes.
Pharm Res
2022
PubMed ID: 36163411
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|
20873
Yamamura N, Mikkaichi T, Itokawa KI, Hoshi M, Damme K, Geigner S, Baumhauer C.
Mirogabalin, a novel α2δ ligand, is not a substrate of LAT1, but of PEPT1, PEPT2, OAT1, OAT3, OCT2, MATE1 and MATE2-K.
Xenobiotica
2022
1-42
PubMed ID: 36170033
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12798
Johmura Y, Yamanaka T, Omori S, Wang TW, Sugiura Y, Matsumoto M, Suzuki N, Kumamoto S, Yamaguchi K, Hatakeyama S, Takami T, Yamaguchi R, Shimizu E, Ikeda K, Okahashi N, Mikawa R, Suematsu M, Arita M, Sugimoto M, Nakayama KI, Furukawa Y, Imoto S, Nakanishi M.
Senolysis by glutaminolysis inhibition ameliorates various age-associated disorders
Science
2021
371(6526):265-270
PubMed ID: 33446552
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13320
Matsumoto N, Sekiya M, Fujimoto Y, Haga S, Sun-Wada GH, Wada Y, Nakanishi-Matsui M.
Functional complementation of V-ATPase a subunit isoforms in osteoclasts.
J Biochem
2021
169(4):459-466
PubMed ID: 33135054
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13345
Daifu T, Mikami M, Hiramatsu H, Iwai A, Umeda K, Noura M, Kubota H, Masuda T, Furuichi K, Takasaki S, Noguchi Y, Morita K, Bando T, Hirata M, Kataoka TR, Nakahata T, Kuwahara Y, Iehara T, Hosoi H, Takita J, Sugiyama H, Adachi S, Kamikubo Y.
Suppression of malignant rhabdoid tumors through Chb-M'-mediated RUNX1 inhibition.
Pediatr Blood Cancer
2021
PubMed ID: 33180377
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13351
Matsumoto Y, Kishida K, Matsumoto M, Matsuoka S, Kohyama M, Suenaga T, Arase H.
A TCR-like antibody against a proinsulin-containing fusion peptide ameliorates type 1 diabetes in NOD mice.
Biochem Biophys Res Commun
2021
PubMed ID: 33208230
|
|
13463
Shota Someya et al
Tryptophan Metabolism Regulates Proliferative Capacity of Human Pluripotent Stem Cells
iScienc
2021
24
PubMed ID: 33615198
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|
20008
Umaba R, Kitanishi T, Mizuseki K.
Monosynaptic connection from the subiculum to medial mammillary nucleus neurons projecting to the anterior thalamus and Gudden's ventral tegmental nucleus.
Neurosci Res
2021
PubMed ID: 33476683
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|
20053
Takafuji S, Mori T, Nishimura N, Yamamoto N, Uemura S, Nozu K, Terui K, Toki T, Ito E, Muramatsu H, Takahashi Y, Matsuo M, Yamamura T, Iijima K.
Usefulness of functional splicing analysis to confirm precise disease pathogenesis in Diamond-Blackfan anemia caused by intronic variants in RPS19.
Pediatr Hematol Oncol
2021
1-16
PubMed ID: 33622161
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20060
Nishiike Y, Miyazoe D, Togawa R, Yokoyama K, Nakasone K, Miyata M, Kikuchi Y, Kamei Y, Todo T, Ishikawa-Fujiwara T, Ohno K, Usami T, Nagahama Y, Okubo K.
Estrogen receptor 2b is the major determinant of sex-typical mating behavior and sexual preference in medaka.
Curr Biol
2021
PubMed ID: 33639108
|
|
13513
Takahashi Y, Wake H, Sakaguchi M, Yoshii Y, Teshigawara K, Wang D, Nishibori M.
Histidine-Rich Glycoprotein Stimulates Human Neutrophil Phagocytosis and Prolongs Survival through CLEC1A
J Immunol
2021
206(4):737-750
PubMed ID: 33452125
|
|
20067
Aizawa N, Fujimori Y, Nakanishi O, Hayashi T, Goi Y, Kobayashi JI, Fujita T.
Efficacy of the combination of KPR-5714, a novel transient receptor potential melastatin 8 (TRPM8) antagonist, and β3-adrenoceptor agonist or anticholinergic agent on bladder dysfunction in rats with bladder overactivity.
Eur J Pharmacol
2021
173995
PubMed ID: 33675781
|
|
20068
Nakamura R, Oyama T, Inokuchi M, Ishikawa S, Hirata M, Kawashima H, Ikeda H, Dobashi Y, Ooi A.
Neural EGFL like 2 expressed in myoepithelial cells and suppressed breast cancer cell migration.
Pathol Int
2021
PubMed ID: 33657249
|
|
13640
Fujita K, Koide N, Somiya M, Kuroda S, Hinuma S.
A regulatory role of scavenger receptor class B type 1 in endocytosis and lipid droplet formation induced by liposomes containing phosphatidylethanolamine in HEK293T cells
Biochim Biophys Acta Mol Cell Res
2021
1868(1):118859
PubMed ID: 32956759
|
|
20083
Hama K, Fujiwara Y, Hayama T, Ozawa T, Nozawa K, Matsuda K, Hashiguchi Y, Yokoyama K.
Very long-chain fatty acids are accumulated in triacylglycerol and nonesterified forms in colorectal cancer tissues.
Sci Rep
2021
11(1):6163
PubMed ID: 33731797
|
|
20103
McKee HK, Kajiwara C, Yamaguchi T, Ishii Y, Shimizu N, Ohara A, Tateda K.
Clostridioides difficile toxins enhanced the in vitro production of CXC chemokine ligand 2 and tumor necrosis factor-α via Toll-like receptors in macrophages.
J Med Microbiol
2021
70(4)
PubMed ID: 33830910
|
|
13898
Takuma Kitanishi, Ryoko Umaba, Kenji Mizuseki
Robust information routing by dorsal subiculum neurons
Sci Adv
2021
7(11):eabf1913
PubMed ID: 33692111
|
|
20114
Ojiro I, Nishio H, Yamazaki-Ito T, Nakano S, Ito S, Toyohara Y, Hiramoto T, Terada Y, Ito K.
Trp-Trp acts as a multi-functional blocker for human bitter taste receptors, hTAS2R14, hTAS2R16, hTAS2R43, and hTAS2R46.
Biosci Biotechnol Biochem
2021
PubMed ID: 33844825
|
|
20138
Nagumo Y, Kandori S, Tanuma K, Nitta S, Chihara I, Shiga M, Hoshi A, Negoro H, Kojima T, Mathis BJ, Funakoshi Y, Nishiyama H.
PLD1 promotes tumor invasion by regulation of MMP-13 expression via NF-κB signaling in bladder cancer.
Cancer Lett
2021
511:15-25
PubMed ID: 33945837
|
|
20147
Kariya Y, Oyama M, Suzuki T, Kariya Y.
αvβ3 Integrin induces partial EMT independent of TGF-β signaling.
Commun Biol
2021
4(1):490
PubMed ID: 33883697
|
|
14182
Somiya M, Kuroda S.
Real-Time Luminescence Assay for Cytoplasmic Cargo Delivery of Extracellular Vesicles
Anal Chem
2021
93(13):5612-5620
PubMed ID: 33759512
|
|
20150
Takeshita M, Suzuki K, Nakazawa M, Kamata H, Ishii M, Oyamada Y, Oshima H, Takeuchi T.
Antigen-driven autoantibody production in lungs of interstitial lung disease with autoimmune disease.
J Autoimmun
2021
121:102661
PubMed ID: 34034155
|
|
20155
Sahoo PR, Kowada T, Mizukami S.
Long-Term Mg2+ Imaging in Live Cells with a Targetable Fluorescent Probe.
Methods Mol Biol
2021
2274:237-243
PubMed ID: 34050476
|
|
20157
Matsui H, Ito J, Matsui N, Uechi T, Onodera O, Kakita A.
Cytosolic dsDNA of mitochondrial origin induces cytotoxicity and neurodegeneration in cellular and zebrafish models of Parkinson's disease.
Nat Commun
2021
12(1):3101
PubMed ID: 34035300
|
|
20158
Osakabe K, Wada N, Murakami E, Miyashita N, Osakabe Y.
Genome editing in mammalian cells using the CRISPR type I-D nuclease.
Nucleic Acids Res
2021
PubMed ID: 34076237
|
|
20165
Kobayashi JI, Hirasawa H, Fujimori Y, Nakanishi O, Kamada N, Ikeda T, Yamamoto A, Kanbe H.
Identification of N-acyl-N-indanyl-α-phenylglycinamides as selective TRPM8 antagonists designed to mitigate the risk of adverse effects.
Bioorg Med Chem
2021
30:115903
PubMed ID: 33333445
|
|
14478
Yamanaka D, Shoda M, Matsubara T, Ishibashi KI, Motoi A, Motoi R, Motoi M, Ohno N, Adachi Y.
Open-Label Study of the Influence of Food Containing the Royal Sun Mushroom, Agaricus brasiliensis KA21 (Agaricomycetes), on β-Glucan-Specific Antibody Production in Healthy Human Volunteers
Int J Med Mushrooms
2021
23(2):13-28
PubMed ID: 33639078
|
|
20199
Tomita T, Kato M, Mishima T, Matsunaga Y, Sanjo H, Ito KI, Minagawa K, Matsui T, Oikawa H, Takahashi S, Takao T, Iwai N, Mino T, Takeuchi O, Maru Y, Hiratsuka S.
Extracellular mRNA transported to the nucleus exerts translation-independent function.
Nat Commun
2021
12(1):3655
PubMed ID: 34135341
|
|
20200
Kuwabara S, Tanimoto Y, Okutani M, Jie M, Haseda Y, Kinugasa-Katayama Y, Aoshi T.
Microfluidics sorting enables the isolation of an intact cellular pair complex of CD8+ T cells and antigen-presenting cells in a cognate antigen recognition-dependent manner.
PLoS One
2021
16(6):e0252666
PubMed ID: 34125844
|
|
20216
Niinae T, Imami K, Sugiyama N, Ishihama Y.
Identification of Endogenous Kinase Substrates by Proximity Labeling Combined with Kinase Perturbation and Phosphorylation Motifs.
Mol Cell Proteomics
2021
100119
PubMed ID: 34186244
|
|
14782
Uemura K, Sasaki M, Sanaki T, Toba S, Takahashi Y, Orba Y, Hall WW, Maenaka K, Sawa H, Sato A.
MRC5 cells engineered to express ACE2 serve as a model system for the discovery of antivirals targeting SARS-CoV-2
Sci Rep
2021
11(1):5376
PubMed ID: 33686154
|
|
14827
iu Y, Soh WT, Kishikawa JI, Hirose M, Nakayama EE, Li S, Sasai M, Suzuki T, Tada A, Arakawa A, Matsuoka S, Akamatsu K, Matsuda M, Ono C, Torii S, Kishida K, Jin H, Nakai W, Arase N, Nakagawa A, Matsumoto M, Nakazaki Y, Shindo Y, Kohyama M, Tomii K, Ohmura K, Ohshima S, Okamoto T, Yamamoto M, Nakagami H, Matsuura Y, Nakagawa A, Kato T, Okada M, Standley DM, Shioda T, Arase H.
An infectivity-enhancing site on the SARS-CoV-2 spike protein targeted by antibodies
Cell
2021
184(13):3452-3466.e18
PubMed ID: 34139176
|
|
20233
Koshizuka T, Kondo H, Kato H, Takahashi K.
Human cytomegalovirus UL42 protein inhibits the degradation of glycoprotein B through inhibition of Nedd4 family ubiquitin E3 ligases.
Microbiol Immunol
2021
PubMed ID: 34260096
|
|
20240
Kaku T, Sugiura K, Entani T, Osabe K, Nagai T.
Enhanced brightness of bacterial luciferase by bioluminescence resonance energy transfer.
Sci Rep
2021
11(1):14994
PubMed ID: 34294849
|
|
14939
Shuji Hinuma, Kazuyo Fujita, Shun’ichi Kuroda
Binding of Nanoparticles Harboring Recombinant Large Surface Protein of Hepatitis B Virus to Scavenger Receptor Class B Type 1
Viruses
2021
13:1334
|
|
20244
Yoshioka K, Obara K, Oikawa S, Uemura K, Yamaguchi A, Fujisawa K, Hanazawa H, Fujiwara M, Endoh T, Suzuki T, Regadera MD, Ito D, Ou G, Xu K, Tanaka Y.
Docosahexaenoic acid inhibits U46619- and prostaglandin F2α-induced pig coronary and basilar artery contractions by inhibiting prostanoid TP receptors.
Eur J Pharmacol
2021
174371
PubMed ID: 34329614
|
|
20272
Ma Y, Yoshida T, Matoba K, Kida K, Shintani R, Piao Y, Jin J, Nishino T, Hanayama R.
Identification of small compounds regulating the secretion of extracellular vesicles via a TIM4-affinity ELISA.
Sci Rep
2021
11(1):13471
PubMed ID: 34188113
|
|
15168
Hangai S, Kawamura T, Kimura Y, Chang CY, Hibino S, Yamamoto D, Nakai Y, Tateishi R, Oshima M, Oshima H, Kodama T, Moriya K, Koike K, Yanai H, Taniguchi T.
Orchestration of myeloid-derived suppressor cells in the tumor microenvironment by ubiquitous cellular protein TCTP released by tumor cells
Nat Immunol
2021
22(8):947-957
PubMed ID: 34239121
|
|
20282
Nakanishi E, Uemura N, Akiyama H, Kinoshita M, Masanori S, Taruno Y, Yamakado H, Matsuzawa SI, Takeda S, Hirabayashi Y, Takahashi R.
Impact of Gba2 on neuronopathic Gaucher's disease and α-synuclein accumulation in medaka (Oryzias latipes).
Mol Brain
2021
14(1):80
PubMed ID: 33971917
|
|
20283
Sakoguchi A, Saito F, Hirayasu K, Shida K, Matsuoka S, Itagaki S, Nakai W, Kohyama M, Suenaga T, Iwanaga S, Horii T, Arase H.
Plasmodium falciparum RIFIN is a novel ligand for inhibitory immune receptor LILRB2.
Biochem Biophys Res Commun
2021
548:167-173
PubMed ID: 33647792
|
|
20298
Nagano C, Takaoka Y, Kamei K, Hamada R, Ichikawa D, Tanaka K, Aoto Y, Ishiko S, Rossanti R, Sakakibara N, Okada E, Horinouchi T, Yamamura T, Tsuji Y, Noguchi Y, Ishimori S, Nagase H, Ninchoji T, Iijima K, Nozu K.
Genotype-Phenotype Correlation in WT1 Exon 8 to 9 Missense Variants.
Kidney Int Rep
2021
6(8):2114-2121
PubMed ID: 34386660
|
|
20322
Fujisawa S, Qiu H, Nozaki S, Chiba S, Katoh Y, Nakayama K.
ARL3 and ARL13B GTPases participate in distinct steps of INPP5E targeting to the ciliary membrane.
Biol Open
2021
PubMed ID: 34447983
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15284
Yoshiko Iizuka, Kinuko Inomata, Risako Nohara, Akimitsu Miyawaki and Yoshifumi Watanabe
Activation of intracellular antioxidant master gene Nrf2 by the extracts of Garcinia subelliptica, Ocimum gratissimum L., and Plectranthus ornatus
International Journal of Herbal Medicine
2021
9(3):54-60
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15524
Fukasawa K, Kadota T, Horie T, Tokumura K, Terada R, Kitaguchi Y, Park G, Ochiai S, Iwahashi S, Okayama Y, Hiraiwa M, Yamada T, Iezaki T, Kaneda K, Yamamoto M, Kitao T, Shirahase H, Hazawa M, Wong RW, Todo T, Hirao A, Hinoi E.
CDK8 maintains stemness and tumorigenicity of glioma stem cells by regulating the c-MYC pathway
Oncogene
2021
40(15):2803-2815
PubMed ID: 33727660
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20354
Noguchi T, Nakamura K, Satoda Y, Katoh Y, Nakayama K.
CCRK/CDK20 regulates ciliary retrograde protein trafficking via interacting with BROMI/TBC1D32.
PLoS One
2021
16(10):e0258497
PubMed ID: 34624068
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20356
Yasumura M, Hagiwara A, Hida Y, Ohtsuka T.
Planar cell polarity protein Vangl2 and its interacting protein Ap2m1 regulate dendritic branching in cortical neurons.
Genes Cells
2021
PubMed ID: 34626136
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20367
Kariya Y, Oyama M, Kariya Y, Hashimoto Y.
Phosphorylated Osteopontin Secreted from Cancer Cells Induces Cancer Cell Motility.
Biomolecules
2021
11(9)
PubMed ID: 34572536
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20403
Yaguchi A, Oshikawa M, Watanabe G, Hiramatsu H, Uchida N, Hara C, Kaneko N, Sawamoto K, Muraoka T, Ajioka I.
Efficient protein incorporation and release by a jigsaw-shaped self-assembling peptide hydrogel for injured brain regeneration.
Nat Commun
2021
12(1):6623
PubMed ID: 34799548
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20440
Kanadome T, Hoshino N, Nagai T, Matsuda T, Yagi T.
Development of FRET-based indicators for visualizing homophilic trans interaction of a clustered protocadherin.
Sci Rep
2021
11(1):22237
PubMed ID: 34782670
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15879
Uemura K, Nobori H, Sato A, Sanaki T, Toba S, Sasaki M, Murai A, Saito-Tarashima N, Minakawa N, Orba Y, Kariwa H, Hall WW, Sawa H, Matsuda A, Maenaka K.
5-Hydroxymethyltubercidin exhibits potent antiviral activity against flaviviruses and coronaviruses, including SARS-CoV-2
iScience
2021
24(10):103120
PubMed ID: 34541466
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15898
Yafei Liu, Noriko Arase, Jun-ichi Kishikawa, Mika Hirose, Songling Li, Asa Tada, Sumiko Matsuoka, Akemi Arakawa, Kanako Akamatsu, Chikako Ono, Hui Jin, Kazuki Kishida, Wataru Nakai, Masako Kohyama, Atsushi Nakagawa, Yoshiaki Yamagishi, Hironori Nakagami, Atsushi Kumanogoh, Yoshiharu Matsuura, Daron M. Standley, Takayuki Kato, Masato Okada, Manabu Fujimoto, Hisashi Arase
The SARS-CoV-2 Delta variant is poised to acquire complete resistance to wild-type spike vaccines
bioRxiv
2021
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20490
Ito F, Kato K, Yanatori I, Murohara T, Toyokuni S.
Ferroptosis-dependent extracellular vesicles from macrophage contribute to asbestos-induced mesothelial carcinogenesis through loading ferritin.
Redox Biol
2021
47:102174
PubMed ID: 34700146
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20493
Ishida H, Murakami S, Kamiki H, Matsugo H, Katayama M, Sekine W, Ohira K, Takenaka-Uema A, Horimoto T.
Construction of an Influenza D Virus with an Eight-Segmented Genome.
Viruses
2021
13(11)
PubMed ID: 34834971
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16115
Masuo K, Chen R, Yogo A, Sugiyama A, Fukuda A, Masui T, Uemoto S, Seno H, Takaishi S.
SNAIL2 contributes to tumorigenicity and chemotherapy resistance in pancreatic cancer by regulating IGFBP2
Cancer Sci
2021
112(12):4987-4999
PubMed ID: 34628696
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16241
Somiya M, Kuroda S.
Reporter gene assay for membrane fusion of extracellular vesicles
J Extracell Vesicles
2021
10(13):e12171
PubMed ID: 34807503
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16324
Sheng J, Kohno S, Okada N, Okahashi N, Teranishi K, Matsuda F, Shimizu H, Linn P, Nagatani N, Yamamura M, Harada K, Horike SI, Inoue H, Yano S, Kumar S, Kitajima S, Ajioka I, Takahashi C.
Treatment of Retinoblastoma 1-Intact Hepatocellular Carcinoma With Cyclin-Dependent Kinase 4/6 Inhibitor Combination Therapy
Hepatology
2021
74(4):1971-1993
PubMed ID: 33931882
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16704
PACAP-PAC1 Signaling Regulates Serotonin 2A Receptor Internalization
PACAP-PAC1 Signaling Regulates Serotonin 2A Receptor Internalization
Front Endocrinol (Lausanne)
2021
12:73245
PubMed ID: 34759890
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16752
Ishii M, Ando J, Yamazaki S, Toyota T, Ohara K, Furukawa Y, Suehara Y, Nakanishi M, Nakashima K, Ohshima K, Nakauchi H, Ando M.
iPSC-Derived Neoantigen-Specific CTL Therapy for Ewing Sarcoma
Cancer Immunol Res
2021
9(10):1175-1186
PubMed ID: 34385178
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16759
Oda K, Matoba Y, Sugiyama M, Sakaguchi T.
Structural Insight into the Interaction of Sendai Virus C Protein with Alix To Stimulate Viral Budding
J Virol
2021
95(19):e0081521
PubMed ID: 34287046
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16762
Wang W, Zhu Y, Sun Z, Jin C, Wang X.
Positive feedback regulation between USP15 and ERK2 inhibits osteoarthritis progression through TGF-β/SMAD2 signaling
Arthritis Res Ther
2021
23(1):84
PubMed ID: 33726807
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16764
Pham Tuan Huy Nguyen Pham Quynh Anh Tong Thi Hang Nguyen Hoang Khue Tu Le Minh Thong Nguyen Van Thuan Yen Thi Hai Tran
Home-made in vitro magnetic nanoparticle-based gene delivery system
Science & Technology Development Journal
2021
24:2058-2065
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16766
Ohn J, Been KW, Kim JY, Kim EJ, Park T, Yoon HJ, Ji JS, Okada-Iwabu M, Iwabu M, Yamauchi T, Kim YK, Seok C, Kwon O, Kim KH, Lee HH, Chung JH.
Discovery of a transdermally deliverable pentapeptide for activating AdipoR1 to promote hair growth
EMBO Mol Med
2021
13(10):e13790
PubMed ID: 34486824
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11854
Yamamoto M, Terada Y, Motoyama T, Saito T, Ito K.
Sweet proteins lysozyme and thaumatin are protein-type agonists for the calcium-sensing receptor.
Biochem. Biophys. Res. Commun.
2020
521(1):227-231
PubMed ID: 31635806
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6889
Iuchi K, Oya K, Hosoya K, Sasaki K, Sakurada Y, Nakano T, Hisatomi H.
Different morphologies of human embryonic kidney 293T cells in various types of culture dishes.
Cytotechnology
2020
72(1):131-140
PubMed ID: 31865498
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9863
Naomi Matsumoto, Reina Matsukawa, Shohei Takahashi, Koshi Kudo, Ge-Hong Sun-Wada, Yoh Wada, Mayumi Nakanishi-Matsui
V-ATPase a3 Isoform Mutations Identified in Osteopetrosis Patients Abolish Its Expression and Disrupt Osteoclast Function
Exp Cell Res
2020
389(2):111901
PubMed ID: 32045577
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9912
Hiroshi Suzuki, Yuichi Ozaki, Shigeho Ijiri, Koichiro Gen, Yukinori Kazeto
17β-Hydroxysteroid Dehydrogenase Type 12a Responsible for Testicular 11-ketotestosterone Synthesis in the Japanese Eel, Anguilla Japonica
J Steroid Biochem Mol Biol
2020
198:105550
PubMed ID: 31778803
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10370
Yusuke Higuchi, Jun-Ichirou Yasunaga, Yu Mitagami, Hirotake Tsukamoto, Kazutaka Nakashima, Koichi Ohshima, Masao Matsuoka
HTLV-1 Induces T Cell Malignancy and Inflammation by Viral Antisense Factor-Mediated Modulation of the Cytokine Signaling
Proc Natl Acad Sci U S A
2020
117(24):13740-13749
PubMed ID: 32471947
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11909
Sakaue T, Hamaguchi M, Aono J, Nakashiro KI, Shikata F, Kawakami N, Oshima Y, Kurata M, Nanba D, Masumoto J, Yamaguchi O, Higashiyama S, Izutani H.
Valve Interstitial Cell-Specific Cyclooxygenase-1 Associated With Calcification of Aortic Valves.
Ann. Thorac. Surg
2020
110(1):40-49
PubMed ID: 31760051
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11927
Yang J, Isaji T, Zhang G, Qi F, Duan C, Fukuda T, Gu J.
EpCAM associates with integrin and regulates cell adhesion in cancer cells.
Biochem. Biophys. Res. Commun.
2020
PubMed ID: 31806375
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11944
Qi F, Isaji T, Duan C, Yang J, Wang Y, Fukuda T, Gu J.
ST3GAL3, ST3GAL4, and ST3GAL6 differ in their regulation of biological functions via the specificities for the α2,3-sialylation of target proteins.
FASEB J.
2020
PubMed ID: 31914669
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11952
Kimura R, Yoshimaru T, Matsushita Y, Matsuo T, Ono M, Park JH, Sasa M, Miyoshi Y, Nakamura Y, Katagiri T.
The GALNT6‑LGALS3BP axis promotes breast cancer cell growth.
Int. J. Oncol.
2020
PubMed ID: 31894262
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11958
Hou S, Hang Q, Isaji T, Fukuda T, Gu J.
Identification of the minimal N-glycosylation on integrin α5β1 required for its inhibitory effect on EGFR signaling and cell proliferation.
Biochem. Biophys. Res. Commun.
2020
PubMed ID: 31858971
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11990
Duan C, Fukuda T, Isaji T, Qi F, Yang J, Wang Y, Takahashi S, Gu J.
Deficiency of core fucosylation activates cellular signaling dependent on FLT3 expression in a Ba/F3 cell system.
FASEB J.
2020
PubMed ID: 31908039
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12005
Kabayama H, Takeuchi M, Tokushige N, Muramatsu SI, Kabayama M, Fukuda M, Yamada Y, Mikoshiba K.
An ultra-stable cytoplasmic antibody engineered for in vivo applications.
Nat Commun
2020
PubMed ID: 31953402
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12015
Yamamoto H, Kon T, Omori Y, Furukawa T.
Functional and Evolutionary Diversification of Otx2 and Crx in Vertebrate Retinal Photoreceptor and Bipolar Cell Development.
Cell Rep
2020
PubMed ID: 31968244
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12027
Momoi Y, Nishikimi A, Du G, Kataoka T, Katagiri K.
Phosphatidic acid regulates subcellular distribution of RA-GEFs critical for chemokine-dependent migration.
Biochem. Biophys. Res. Commun.
2020
PubMed ID: 31996307
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12028
Iuchi K, Tasaki Y, Shirai S, Hisatomi H.
Upregulation of nuclear factor (erythroid-derived 2)-like 2 protein level in the human colorectal adenocarcinoma cell line DLD-1 by a heterocyclic organobismuth(III) compound: Effect of organobismuth(III) compound on NRF2 signaling.
Biomed. Pharmacother.
2020
PubMed ID: 32004978
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12086
Honda A, Chigwechokha PK, Takase R, Hayasaka O, Fujimura K, Kotani T, Komatsu M, Shiozaki K.
Novel Nile tilapia Neu1 sialidases: Molecular cloning and biochemical characterization of the sialidases Neu1a and Neu1b.
Gene
2020
PubMed ID: 32184168
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12096
Funakoshi-Tago M, Yu S, Kushida A, Takeuchi K, Tamura H.
Kampo medicines, Rokumigan, Hachimijiogan, and Goshajinkigan, significantly inhibit glucagon-induced CREB activation.
Heliyon
2020
PubMed ID: 32215330
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12129
Mutai H, Wasano K, Momozawa Y, Kamatani Y, Miya F, Masuda S, Morimoto N, Nara K, Takahashi S, Tsunoda T, Homma K, Kubo M, Matsunaga T.
Variants encoding a restricted carboxy-terminal domain of SLC12A2 cause hereditary hearing loss in humans.
PLoS Genet.
2020
PubMed ID: 32294086
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12364
Liu X, Tajima N, Taniguchi M, Kato N.
The enantiomer pair of 24S- and 24R-hydroxycholesterol differentially alter activity of large-conductance Ca 2+ -dependent K + (slo1 BK) channel
Chirality
2020
32(2):223-230
PubMed ID: 31756018
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12487
Yafei Liu et al
An infectivity-enhancing site on the SARS-CoV-2 spike protein is targeted by COVID-19 patient antibodies
bioRxiv
2020
December 18
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13019
Matsuzaki M, Mandai M, Yamanari M, Totani K, Nishida M, Sugita S, Maeda T, Koide N, Takagi S, Hirami Y, Miyamoto N, Sugiyama S, Takahashi M, Kurimoto Y.
Polarization-sensitive optical coherence tomography for estimating relative melanin content of autologous induced stem-cell derived retinal pigment epithelium.
Sci Rep
2020
PubMed ID: 32376945
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13020
Koshizuka T, Inoue N.
Activation of c-Jun by human cytomegalovirus UL42 through JNK activation.
PLoS One
2020
PubMed ID: 32369499
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13024
Kanoh H, Nitta T, Go S, Inamori KI, Veillon L, Nihei W, Fujii M, Kabayama K, Shimoyama A, Fukase K, Ohto U, Shimizu T, Watanabe T, Shindo H, Aoki S, Sato K, Nagasaki M, Yatomi Y, Komura N, Ando H, Ishida H, Kiso M, Natori Y, Yoshimura Y, Zonca A, Cattaneo A, Letizia M, Ciampa M, Mauri L, Prinetti A, Sonnino S, Suzuki A, Inokuchi JI.
Homeostatic and pathogenic roles of GM3 ganglioside molecular species in TLR4 signaling in obesity.
EMBO J
2020
PubMed ID: 32378734
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13028
Kido K, Yamanaka S, Nakano S, Motani K, Shinohara S, Nozawa A, Kosako H, Ito S, Sawasaki T.
AirID, a novel proximity biotinylation enzyme, for analysis of protein-protein interactions.
Elife
2020
PubMed ID: 32391793
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13034
Bajkowska K, Sumardika IW, Tomonobu N, Chen Y, Yamamoto KI, Kinoshita R, Murata H, Gede Yoni Komalasari NL, Jiang F, Yamauchi A, Winarsa Ruma IM, Kasano-Camones CI, Inoue Y, Sakaguchi M.
Neuroplastinβ-mediated upregulation of solute carrier family 22 member 18 antisense (SLC22A18AS) plays a crucial role in the epithelial-mesenchymal transition, leading to lung cancer cells' enhanced motility.
Biochem Biophys Rep
2020
PubMed ID: 32490214
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13044
Park M, Miyoshi C, Fujiyama T, Kakizaki M, Ikkyu A, Honda T, Choi J, Asano F, Mizuno S, Takahashi S, Yanagisawa M, Funato H.
Loss of the conserved PKA sites of SIK1 and SIK2 increases sleep need.
Sci Rep
2020
PubMed ID: 32457359
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13074
Horinouchi T, Yamamura T, Minamikawa S, Nagano C, Sakakibara N, Nakanishi K, Shima Y, Morisada N, Ishiko S, Aoto Y, Nagase H, Takeda H, Rossanti R, Ishimori S, Kaito H, Matsuo M, Iijima K, Nozu K.
Pathogenic evaluation of synonymous COL4A5 variants in X-linked Alport syndrome using a minigene assay.
Mol Genet Genomic Med
2020
PubMed ID: 32543079
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13080
Ito F, Yanatori I, Maeda Y, Nimura K, Ito S, Hirayama T, Nagasawa H, Kohyama N, Okazaki Y, Akatsuka S, Toyokuni S.
Asbestos conceives Fe(II)-dependent mutagenic stromal milieu through ceaseless macrophage ferroptosis and β-catenin induction in mesothelium.
Redox Biol
2020
PubMed ID: 32863225
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13164
Yamashita J, Takeuchi A, Hosono K, Fleming T, Nagahama Y, Okubo K.
Male-predominant galanin mediates androgen-dependent aggressive chases in medaka.
Elife
2020
PubMed ID: 32783809
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13182
Ishibashi R, Abe K, Ido N, Kitano S, Miyachi H, Toyoshima F.
Genome editing with the donor plasmid equipped with synthetic crRNA-target sequence.
Sci Rep
2020
PubMed ID: 32839482
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13186
Huetter J, Gritzan U, Gutcher I, Doecke WD, Luetke-Eversloh MV, Golfier S, Roider HG, Frisk AL, Hunter J, Pow A, Drake A, Levine Z, Levy O, Azulay M, Barbiro I, Cojocaru G, Vaknin I, Kreft B, Roese L.
Characterization of BAY 1905254, an Immune Checkpoint Inhibitor Targeting the Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2).
Cancer Immunol Res
2020
PubMed ID: 32312711
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13199
Kakizawa S, Kishimoto Y, Yamamoto S, Onga K, Yasuda K, Miyamoto Y, Watanabe M, Sakai R, Mori N.
Functional maintenance of calcium store by ShcB adaptor protein in cerebellar Purkinje cells.
Sci Rep
2020
PubMed ID: 32879382
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13200
Ago Y, Otsuka H, Sasai H, Abdelkreem E, Nakama M, Aoyama Y, Matsumoto H, Fujiki R, Ohara O, Akiyama K, Fukui K, Watanabe Y, Nakajima Y, Ohnishi H, Ito T, Fukao T.
Japanese patients with mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase deficiency: In vitro functional analysis of five novel HMGCS2 mutations.
Exp Ther Med
2020
PubMed ID: 32952630
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13204
Kinoshita N, Huang AJY, McHugh TJ, Miyawaki A, Shimogori T.
Diffusible GRAPHIC to visualize morphology of cells after specific cell-cell contact.
Sci Rep
2020
PubMed ID: 32879377
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13212
Kitao T, Taguchi K, Seto S, Arasaki K, Ando H, Nagai H, Kubori T.
Legionella Manipulates Non-canonical SNARE Pairing Using a Bacterial Deubiquitinase.
Cell Rep
2020
PubMed ID: 32905772
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13276
Arai Y, Kawashita N, Elgendy EM, Ibrahim MS, Daidoji T, Ono T, Takagi T, Nakaya T, Matsumoto K, Watanabe Y.
PA Mutations Inherited during Viral Evolution Act Cooperatively To Increase Replication of Contemporary H5N1 Influenza Virus with an Expanded Host Range.
J Virol
2020
PubMed ID: 33028722
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13293
Okamura M, Shizu R, Abe T, Kodama S, Hosaka T, Sasaki T, Yoshinari K.
PXR Functionally Interacts with NF-κB and AP-1 to Downregulate the Inflammation-Induced Expression of Chemokine CXCL2 in Mice.
Cells
2020
PubMed ID: 33076328
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13321
Kato M, Onoyama I, Kawakami M, Yoshida S, Kawamura K, Kodama K, Hori E, Cui L, Matsumura Y, Yagi H, Asanoma K, Yahata H, Itakura A, Takeda S, Kato K.
Downregulation of 5-hydroxymethylcytosine is associated with the progression of cervical intraepithelial neoplasia.
PLoS One
2020
PubMed ID: 33141854
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13327
Yamazaki T, Takahashi C, Taniguchi Y, Narukawa M, Misaka T, Ano Y.
Bitter taste receptor activation by hop-derived bitter components induces gastrointestinal hormone production in enteroendocrine cells.
Biochem Biophys Res Commun
2020
PubMed ID: 33160623
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13330
Osakabe K, Wada N, Miyaji T, Murakami E, Marui K, Ueta R, Hashimoto R, Abe-Hara C, Kong B, Yano K, Osakabe Y.
Genome editing in plants using CRISPR type I-D nuclease.
Commun Biol
2020
3(1):648
PubMed ID: 33159140
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13490
Shoji S, Hanada K, Takahashi M, Watanabe K, Yonemochi M, Tomabechi Y, Shirouzu M.
The NF-κB regulator IκBβ exhibits different molecular interactivity and phosphorylation status from IκBα in an IKK2-catalysed reaction
FEBS Lett
2020
594(10):1532-1549
PubMed ID: 32017069
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13554
Tohama T, Sakari M, Tsukahara T.
Development of a Single Construct System for Site-Directed RNA Editing Using MS2-ADAR
Int J Mol Sci
2020
;21(14):4943
PubMed ID: 32668759
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13567
Harada M, Nghia VT, Nakao A, Tanigaki R, Fukuoka N, Nishida A, Kataoka T.
Eomesodermin promotes interaction of RelA and NFATc2 with the Ifng promoter and multiple conserved noncoding sequences across the Ifng locus in mouse lymphoma BW5147 cells
Immunol Lett
2020
225:33-43
PubMed ID: 32554052
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13570
Suzuki T, Morimoto N, Akaike A, Osakada F.
Multiplex Neural Circuit Tracing With G-Deleted Rabies Viral Vectors
Front Neural Circuits
2020
13:77
PubMed ID: 31998081
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13575
Suzuki F, Okuno M, Tanaka T, Sanuki R.
Overexpression of neural miRNAs miR-9/9* and miR-124 suppresses differentiation to Müller glia and promotes differentiation to neurons in mouse retina in vivo
Genes Cells
2020
25(11):741-752
PubMed ID: 32979863
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13577
Shimada K, Kobayashi N, Oka N, Takahashi M, Kondo K.
Cooperative activation of the human herpesvirus 6B U79/80 early gene promoter by immediate-early proteins IE1B and IE2B
Microbiol Immunol
2020
64(11):747-761
PubMed ID: 32910457
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13599
Murakami S, Mochimaru Y, Musha S, Kojima R, Deai M, Mogi C, Sato K, Okajima F, Tomura H.
Species-Dependent Enhancement of Ovarian Cancer G Protein-Coupled Receptor 1 Activation by Ogerin
Zoolog Sci
2020
37(2):103-108
PubMed ID: 32282140
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13606
Wardhani BW, Puteri MU, Watanabe Y, Louisa M, Setiabudy R, Kato M.
TGF-β-Induced TMEPAI Attenuates the Response of Triple-Negative Breast Cancer Cells to Doxorubicin and Paclitaxel
J Exp Pharmacol
2020
12:17-26
PubMed ID: 32158279
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13629
Yamamoto M, Terada Y, Motoyama T, Shibata M, Saito T, Ito K.
N-terminal [Glu] 3 moiety of γ-glutamyl peptides contributes largely to the activation of human calcium-sensing receptor, a kokumi receptor
Biosci Biotechnol Biochem
2020
84(7):1497-1500
PubMed ID: 32202205
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13772
Sawada Y, Kikugawa T, Iio H, Sakakibara I, Yoshida S, Ikedo A, Yanagihara Y, Saeki N, Győrffy B, Kishida T, Okubo Y, Nakamura Y, Miyagi Y, Saika T, Imai Y.
GPRC5A facilitates cell proliferation through cell cycle regulation and correlates with bone metastasis in prostate cancer
Int J Cancer
2020
146(5):1369-1382
PubMed ID: 31276604
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13913
Rai D, Akagi T, Shimohata A, Ishii T, Gangi M, Maruyama T, Wada-Kiyama Y, Ogiwara I, Kaneda M.
Involvement of the C-terminal domain in cell surface localization and G-protein coupling of mGluR6
J Neurochem
2020
Oct 17
PubMed ID: 33067823
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13917
Tamai K, Nakamura-Shima M, Shibuya-Takahashi R, Kanno SI, Yasui A, Mochizuki M, Iwai W, Wakui Y, Abue M, Yamamoto K, Miura K, Mizuma M, Unno M, Kawamura S, Sato I, Yasuda J, Yamaguchi K,
BEX2 suppresses mitochondrial activity and is required for dormant cancer stem cell maintenance in intrahepatic cholangiocarcinoma
Sci Rep
2020
10(1):21592
PubMed ID: 33299012
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14525
Ishida H, Murakami S, Kamiki H, Matsugo H, Takenaka-Uema A, Horimoto T.
Establishment of a Reverse Genetics System for Influenza D Virus
J Virol
2020
94(10):e01767-19
PubMed ID: 32102883
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14805
Yokomizo-Nakano T, Kubota S, Bai J, Hamashima A, Morii M, Sun Y, Katagiri S, Iimori M, Kanai A, Tanaka D, Oshima M, Harada Y, Ohyashiki K, Iwama A, Harada H, Osato M, Sashida G.
Overexpression of RUNX3 Represses RUNX1 to Drive Transformation of Myelodysplastic Syndrome
Cancer Res
2020
80(12):2523-2536
PubMed ID: 32341038
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14840
Ueo A, Kubota M, Shirogane Y, Ohno S, Hashiguchi T, Yanagi Y.
Lysosome-Associated Membrane Proteins Support the Furin-Mediated Processing of the Mumps Virus Fusion Protein
J Virol
2020
94(12):e00050-20
PubMed ID: 32295904
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14855
Effective RNA Knockdown Using CRISPR-Cas13a and Molecular Targeting of the EML4-ALK Transcript in H3122 Lung Cancer Cells
Effective RNA Knockdown Using CRISPR-Cas13a and Molecular Targeting of the EML4-ALK Transcript in H3122 Lung Cancer Cells
Int J Mol Sci
2020
21(23):8904
PubMed ID: 33255340
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14862
Mizutani T, Ohba Y, Mizuta S, Yasuda J, Urata S.
An Antiviral Drug Screening Platform with a FRET Biosensor for Measurement of Arenavirus Z Assembly
Cell Struct Funct
2020
45(2):155-163
PubMed ID: 33191384
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14868
Toda K, Tsukayama I, Nagasaki Y, Konoike Y, Tamenobu A, Ganeko N, Ito H, Kawakami Y, Takahashi Y, Miki Y, Yamamoto K, Murakami M, Suzuki-Yamamoto T.
Red-kerneled rice proanthocyanidin inhibits arachidonate 5-lipoxygenase and decreases psoriasis-like skin inflammation
Arch Biochem Biophys
2020
689:108307
PubMed ID: 32112739
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16634
Adachi K, Yamada T, Ishizuka H, Oki M, Tsunogae S, Shimada N, Chiba O, Orihara T, Hidaka M, Hirokawa T, Odagi M, Konoki K, Yotsu-Yamashita M, Nagasawa K.
Synthesis of C12-Keto Saxitoxin Derivatives with Unusual Inhibitory Activity Against Voltage-Gated Sodium Channels
Chemistry
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FASEB J.
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11273
Mizuno M, Miki R, Moriyama Y, Ushida T, Imai K, Niimi K, Nakano T, Tsuda H, Sumigama S, Yamamoto E, Senga T, Iwase A, Kikkawa F, Kotani T.
The role of E2F8 in the human placenta.
Mol Med Rep
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Nitta T, Kanoh H, Inamori KI, Suzuki A, Takahashi T, Inokuchi JI.
Globo-series glycosphingolipids enhance Toll-like receptor 4-mediated inflammation and play a pathophysiological role in diabetic nephropathy.
Glycobiology
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11315
Arai Y, Ibrahim MS, Elgendy EM, Daidoji T, Ono T, Suzuki Y, Nakaya T, Matsumoto K, Watanabe Y.
Genetic Compatibility of Reassortants between Avian H5N1 and H9N2 Influenza Viruses with Higher Pathogenicity in Mammals.
J. Virol.
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Ishikawa K, Hara T, Kato K, Shimomura T, Omori K.
Involvement of natriuretic peptide system in C2C12 myocytes.
Mol. Cell. Biochem.
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Xu Z, Isaji T, Fukuda T, Wang Y, Gu J.
O-GlcNAcylation regulates integrin-mediated cell adhesion and migration via formation of focal adhesion complexes.
J. Biol. Chem.
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Suzuki N, Hirano K, Ogino H, Ochi H.
Arid3a regulates nephric tubule regeneration via evolutionarily conserved regeneration signal-response enhancers.
Elife
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Kataoka K, Miyoshi H, Sakata S, Dobashi A, Couronné L, Kogure Y, Sato Y, Nishida K, Gion Y, Shiraishi Y, Tanaka H, Chiba K, Watatani Y, Kakiuchi N, Shiozawa Y, Yoshizato T, Yoshida K, Makishima H, Sanada M, Onozawa M, Teshima T, Yoshiki Y, Ishida T, Suzuki K, Shimada K, Tomita A, Kato M, Ota Y, Izutsu K, Demachi-Okamura A, Akatsuka Y, Miyano S, Yoshino T, Gaulard P, Hermine O, Takeuchi K, Ohshima K, Ogawa S.
Frequent structural variations involving programmed death ligands in Epstein-Barr virus-associated lymphomas.
Leukemia
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11416
Matsumoto N, Nakanishi-Matsui M.
Proton pumping V-ATPase inhibitor bafilomycin A1 affects Rab7 lysosomal localization and abolishes anterograde trafficking of osteoclast secretory lysosomes.
Biochem. Biophys. Res. Commun.
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Shimizu Y, Kohyama M, Yorifuji H, Jin H, Arase N, Suenaga T, Arase H.
FcγRIIIA-mediated activation of NK cells by IgG heavy chain complexed with MHC class II molecules.
Int. Immunol.
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Ishibashi D, Homma T, Nakagaki T, Fuse T, Sano K, Satoh K, Mori T, Atarashi R, Nishida N.
Type I interferon protects neurons from prions in in vivo models.
Brain
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PubMed ID: 30753318
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11475
Yorifuji H, Arase N, Kohyama M, Hirano T, Suenaga T, Kumanogoh A, Arase H.
Transport of cellular misfolded proteins to the cell surface by HLA-B27 free heavy chain.
Biochem. Biophys. Res. Commun.
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Sarkar B, Nishikata I, Nakahata S, Ichikawa T, Shiraga T, Saha HR, Fujii M, Tanaka Y, Shimoda K, Morishita K.
Degradation of p47 by autophagy contributes to CADM1 overexpression in ATLL cells through the activation of NF-κB.
Sci Rep
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Chen Y, Sumardika IW, Tomonobu N, Winarsa Ruma IM, Kinoshita R, Kondo E, Inoue Y, Sato H, Yamauchi A, Murata H, Yamamoto KI, Tomida S, Shien K, Yamamoto H, Soh J, Liu M, Futami J, Sasai K, Katayama H, Kubo M, Putranto EW, Hibino T, Sun B, Nishibori M, Toyooka S, Sakaguchi M.
Melanoma cell adhesion molecule is the driving force behind the dissemination of melanoma upon S100A8/A9 binding in the original skin lesion.
Cancer Lett.
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Yamaguchi S, Tanimoto A, Iwasa S, Otsuguro KI.
TRPM4 and TRPM5 Channels Share Crucial Amino Acid Residues for Ca2+ Sensitivity but Not Significance of PI(4,5)P2.
Int J Mol Sci
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Yokoyama T, Machida K, Iwasaki W, Shigeta T, Nishimoto M, Takahashi M, Sakamoto A, Yonemochi M, Harada Y, Shigematsu H, Shirouzu M, Tadakuma H, Imataka H, Ito T.
HCV IRES Captures an Actively Translating 80S Ribosome.
Mol Cell
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Mizuta H, Kuga K, Suzuki T, Niwa Y, Dohmae N, Simizu S.
C‑mannosylation of R‑spondin2 activates Wnt/β‑catenin signaling and migration activity in human tumor cells.
Int. J. Oncol.
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Liu YY, Tanikawa C, Ueda K, Matsuda K.
INKA2, a novel p53 target that interacts with the serine/threonine kinase PAK4.
Int. J. Oncol.
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Matsubara H, Tanaka R, Tateishi T, Yoshida H, Yamaguchi M, Kataoka T.
The human Bcl-2 family member Bcl-rambo and voltage-dependent anion channels manifest a genetic interaction in Drosophila and cooperatively promote the activation of effector caspases in human cultured cells.
Exp. Cell Res.
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Chen Y, Sumardika IW, Tomonobu N, Kinoshita R, Inoue Y, Iioka H, Mitsui Y, Saito K, Ruma IMW, Sato H, Yamauchi A, Murata H, Yamamoto KI, Tomida S, Shien K, Yamamoto H, Soh J, Futami J, Kubo M, Putranto EW, Murakami T, Liu M, Hibino T, Nishibori M, Kondo E, Toyooka S, Sakaguchi M.
Critical role of the MCAM-ETV4 axis triggered by extracellular S100A8/A9 in breast cancer aggressiveness.
Neoplasia
2019
PubMed ID: 31100639
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11580
Tanaka J, Mabuchi Y, Hata K, Yasuhara R, Takamatsu K, Kujiraoka S, Yukimori A, Takakura I, Sumimoto H, Fukada T, Azuma M, Akiyama H, Nishimura R, Shimane T, Mishima K.
Sox9 regulates the luminal stem/progenitor cell properties of salivary glands.
Exp. Cell Res.
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11621
Arai Y, Kawashita N, Ibrahim MS, Elgendy EM, Daidoji T, Ono T, Takagi T, Nakaya T, Matsumoto K, Watanabe Y.
PB2 mutations arising during H9N2 influenza evolution in the Middle East confer enhanced replication and growth in mammals.
PLoS Pathog.
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Furuse Y, Chaimongkol N, Okamoto M, Oshitani H.
Evolutionary and Functional Diversity of the 5' Untranslated Region of Enterovirus D68: Increased Activity of the Internal Ribosome Entry Site of Viral Strains during the 2010s.
Viruses
2019
PubMed ID: 31288421
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11643
Ishii J, Suzuki A, Kimura T, Tateyama M, Tanaka T, Yazawa T, Arimasu Y, Chen IS, Aoyama K, Kubo Y, Saitoh S, Mizuno H, Kamma H.
Congenital goitrous hypothyroidism is caused by dysfunction of the iodide transporter SLC26A7.
Commun Biol
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PubMed ID: 31372509
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11647
Wong JH, Shigemizu D, Yoshii Y, Akiyama S, Tanaka A, Nakagawa H, Narumiya S, Fujimoto A.
Identification of intermediate-sized deletions and inference of their impact on gene expression in a human population.
Genome Med
2019
PubMed ID: 31340865
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Makino Y, Jensen NH, Yokota N, Rossner MJ, Akiyama H, Shirahige K, Okada Y.
Single cell RNA-sequencing identified Dec2 as a suppressive factor for spermatogonial differentiation by inhibiting Sohlh1 expression.
Sci Rep
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PubMed ID: 30988352
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11720
Yamanashi T, Maki M, Kojima K, Shibukawa A, Tsukamoto T, Chowdhury S, Yamanaka A, Takagi S, Sudo Y.
Quantitation of the neural silencing activity of anion channelrhodopsins in Caenorhabditis elegans and their applicability for long-term illumination.
Sci Rep
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PubMed ID: 31133660
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Su Y, Nichuguti N, Kuroki-Kami A, Fujiwara H.
Sequence-specific retrotransposition of 28S rDNA-specific LINE R2Ol in human cells.
RNA
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PubMed ID: 31434792
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11845
Kamiki H, Matsugo H, Ishida H, Kobayashi-Kitamura T, Sekine W, Takenaka-Uema A, Murakami S, Horimoto T.
Adaptation of H3N2 canine influenza virus to feline cell culture.
PLoS ONE
2019
PubMed ID: 31600274
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11855
Morita A, Aoshima K, Gulay KCM, Onishi S, Shibata Y, Yasui H, Kobayashi A, Kimura T.
High drug efflux pump capacity and low DNA damage response induce doxorubicin resistance in canine hemangiosarcoma cell lines.
Res. Vet. Sci.
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PubMed ID: 31648115
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6886
Musha S, Nagayama S, Murakami S, Kojima R, Deai M, Sato K, Okajima F, Ueharu H, Tomura H.
Protons Differentially Activate TDAG8 Homologs from Various Species.
Zoolog Sci
2019
36(2):105-111
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6931
Nakanishi M, Hino M, Yoshimura M, Amakura Y, Nomoto H.
Identification of sinensetin and nobiletin as major antitrypanosomal factors in a citrus cultivar.
Exp Parasitol
2019
200:24-29
PubMed ID: 30898543
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9468
Kazuyo Fujita, Masaharu Somiya, Shun'ichi Kuroda, Shuji Hinuma
Induction of Lipid Droplets in Non-Macrophage Cells as Well as Macrophages by Liposomes and Exosomes
Biochem Biophys Res Commun
2019
510(1):184-190
PubMed ID: 30678809
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Uchibori R, Teruya T, Ido H, Ohmine K, Sehara Y, Urabe M, Mizukami H, Mineno J, Ozawa K.
Functional Analysis of an Inducible Promoter Driven by Activation Signals from a Chimeric Antigen Receptor
Mol Ther Oncolytics
2019
2:16-25
PubMed ID: 30662937
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12285
Arisa Mitani, Takeshi Kobayashi, Yasuhito Hayashi, Natsuki Matsushita, Sachi Matsushita, Saori Nakao, Naoko Takahira, Atsushi Shiraishi, Yuichi Ohashi
Characterization of doxycycline-dependent inducible Simian Virus 40 large T antigen immortalized human conjunctival epithelial cell line
PLoS One
2019
14(9):e0222454
PubMed ID: 31509592
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12299
Nobuyoshi Tajima, Liu Xiaoyan, Makoto Taniguchi, Nobuo Kato
24S-hydroxycholesterol alters activity of large-conductance Ca 2+-dependent K + (slo1 BK) channel through intercalation into plasma membrane
Biochim Biophys Acta Mol Cell Biol Lipids
2019
1864(10):1525-1535
PubMed ID: 31136842
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12354
Shimizu K, Yamasaki S, Sakurai M, Yumoto N, Ikeda M, Mishima-Tsumagari C, Kukimoto-Niino M, Watanabe T, Kawamura M, Shirouzu M, Fujii SI.
Granzyme A Stimulates pDCs to Promote Adaptive Immunity via Induction of Type I IFN
Front Immunol
2019
10:1450
PubMed ID: 31293597
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12362
Takahashi Y, Takahashi H, Stern PL, Kirita T, Tsuboi A.
Expression of Oncofetal Antigen 5T4 in Murine Taste Papillae
Front Cell Neurosci
2019
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12363
Ichikawa T, Nakahata S, Fujii M, Iha H, Shimoda K, Morishita K.
The regulation of NDRG2 expression during ATLL development after HTLV-1 infection
Biochim Biophys Acta Mol Basis Dis
2019
1865(10):2633-2646
PubMed ID: 31295529
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12365
Okamura M, Shizu R, Hosaka T, Sasaki T, Yoshinari K.
Possible involvement of the competition for the transcriptional coactivator glucocorticoid receptor-interacting protein 1 in the inflammatory signal-dependent suppression of PXR-mediated CYP3A induction in vitro
Drug Metab Pharmacokinet
2019
34(4):272-279
PubMed ID: 31280915
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12367
Mitsui Y, Tomonobu N, Watanabe M, Kinoshita R, Sumardika IW, Youyi C, Murata H, Yamamoto KI, Sadahira T, Rodrigo AGH, Takamatsu H, Araki K, Yamauchi A, Yamamura M, Fujiwara H, Inoue Y, Futami J, Saito K, Iioka H, Kondo E, Nishibori M, Toyooka S, Yamamoto Y, Nasu Y, Sakaguchi M.
Upregulation of Mobility in Pancreatic Cancer Cells by Secreted S100A11 Through Activation of Surrounding Fibroblasts
Oncol Res
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PubMed ID: 31046874
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12437
Hara N, Osago H, Hiyoshi M, Kobayashi-Miura M, Tsuchiya M.
Quantitative analysis of the effects of nicotinamide phosphoribosyltransferase induction on the rates of NAD+ synthesis and breakdown in mammalian cells using stable isotope-labeling combined with mass spectrometry
PLoS One
2019
14(3):e0214000
PubMed ID: 30875389
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12496
Liu Y, Wang Y, Wang F, Pan J, Xu J, Li J, Zhou C, Ding G, Wu Y, Liu X, Sheng J, Huang H.
Mechanism underlying the retarded nuclear translocation of androgen receptor splice variants
Sci China Life Sci
2019
62(2):257-267
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12588
Yoh T, Hatano E, Kasai Y, Fuji H, Nishi K, Toriguchi K, Sueoka H, Ohno M, Seo S, Iwaisako K, Taura K, Yamaguchi R, Kurokawa M, Fujimoto J, Kimura T, Uemoto S, Nishi E.
Serum Nardilysin, a Surrogate Marker for Epithelial-Mesenchymal Transition, Predicts Prognosis of Intrahepatic Cholangiocarcinoma after Surgical Resection
Clin Cancer Res
2019
25(2):619-628
PubMed ID: 30352908
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14890
Maishi N, Kikuchi H, Sato M, Nagao-Kitamoto H, Annan DA, Baba S, Hojo T, Yanagiya M, Ohba Y, Ishii G, Masutomi K, Shinohara N, Hida Y, Hida K.
Development of Immortalized Human Tumor Endothelial Cells from Renal Cancer
Int J Mol Sci
2019
20(18):4595
PubMed ID: 31533313
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Sumardika IW, Chen Y, Tomonobu N, Kinoshita R, Ruma IMW, Sato H, Kondo E, Inoue Y, Yamauchi A, Murata H, Yamamoto KI, Tomida S, Shien K, Yamamoto H, Soh J, Futami J, Putranto EW, Hibino T, Nishibori M, Toyooka S, Sakaguchi M.
Neuroplastin-β mediates S100A8/A9-induced lung cancer disseminative progression
Mol Carcinog
2019
58(6):980-995
PubMed ID: 30720226
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9500
Kanda K, Sakamoto J, Matsumoto Y, Ikuta K, Goto N, Morita Y, Ohno M, Nishi K, Eto K, Kimura Y, Nakanishi Y, Ikegami K, Yoshikawa T, Fukuda A, Kawada K, Sakai Y, Ito A, Yoshida M, Kimura T, Chiba T, Nishi E, Seno H.
Nardilysin controls intestinal tumorigenesis through HDAC1/p53-dependent transcriptional regulation.
JCI Insight
2018
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10788
Koshizuka T, Kobayashi T, Ishioka K, Suzutani T.
Herpesviruses possess conserved proteins for interaction with Nedd4 family ubiquitin E3 ligases.
Sci Rep
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Mochimaru Y, Negishi J, Murakami S, Musha S, Sato K, Okajima F, Tomura H.
Metals Differentially Activate Ovarian Cancer G Protein-Coupled Receptor 1 in Various Species.
Zool. Sci.
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Yamashita W, Takahashi M, Kikkawa T, Gotoh H, Osumi N, Ono K, Nomura T.
Conserved and divergent functions of Pax6 underlie species-specific neurogenic patterns in the developing amniote brain.
Development
2018
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11042
Shigenori Inagaki; Masakazu Agetsuma; Takeharu Nagai
A novel fiber-free technique for brain activity imaging in multiple freely behaving mice
SPIE BiOS
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11080
Wang Y, Cao L, Lee CY, Matsuo T, Wu K, Asher G, Tang L, Saitoh T, Russell J, Klewe-Nebenius D, Wang L, Soya S, Hasegawa E, Cherasse Y, Zhou J, Li Y, Wang T, Zhan X, Miyoshi C, Irukayama Y, Cao J, Meeks JP, Gautron L, Wang Z, Sakurai K, Funato H, Sakurai T, Yanagisawa M, Nagase H, Kobayakawa R, Kobayakawa K, Beutler B, Liu Q.
Large-scale forward genetics screening identifies Trpa1 as a chemosensor for predator odor-evoked innate fear behaviors.
Nat Commun
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Iuchi K, Morisada Y, Yoshino Y, Himuro T, Saito Y, Murakami T, Hisatomi H.
Cold atmospheric-pressure nitrogen plasma induces the production of reactive nitrogen species and cell death by increasing intracellular calcium in HEK293T cells.
Arch. Biochem. Biophys.
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11144
Funakohi-Tago M, Sakata T, Fujiwara S, Sakakura A, Sugai T, Tago K, Tamura H.
Hydroxytyrosol butyrate inhibits 6-OHDA-induced apoptosis through activation of the Nrf2/HO-1 axis in SH-SY5Y cells.
Eur. J. Pharmacol.
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Kawaguchi M, Tani T, Hombu R, Ieda N, Nakagawa H.
Development and cellular application of visible-light-controllable HNO releasers based on caged Piloty's acid.
Chem. Commun. (Camb.)
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Shiozawa Y, Malcovati L, Galli A, Sato-Otsubo A, Kataoka K, Sato Y, Watatani Y, Suzuki H, Yoshizato T, Yoshida K, Sanada M, Makishima H, Shiraishi Y, Chiba K, Hellstrom-Lindberg E, Miyano S, Ogawa S, Cazzola M.
Aberrant splicing and defective mRNA production induced by somatic spliceosome mutations in myelodysplasia.
Nat Commun
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Ageta H, Ageta-Ishihara N, Hitachi K, Karayel O, Onouchi T, Yamaguchi H, Kahyo T, Hatanaka K, Ikegami K, Yoshioka Y, Nakamura K, Kosaka N, Nakatani M, Uezumi A, Ide T, Tsutsumi Y, Sugimura H, Kinoshita M, Ochiya T, Mann M, Setou M, Tsuchida K.
UBL3 modification influences protein sorting to small extracellular vesicles.
Nat Commun
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PubMed ID: 30258067
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Aoshima K, Fukui Y, Gulay KCM, Erdemsurakh O, Morita A, Kobayashi A, Kimura T.
Notch2 signal is required for the maintenance of canine hemangiosarcoma cancer stem cell-like cells.
BMC Vet. Res.
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Ito S, Kayukawa N, Ueda T, Taniguchi H, Morioka Y, Hongo F, Ukimura O.
MRGBP promotes AR-mediated transactivation of KLK3 and TMPRSS2 via acetylation of histone H2A.Z in prostate cancer cells.
Biochim Biophys Acta Gene Regul Mech
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Niino T, Tago K, Yasuda D, Takahashi K, Mashino T, Tamura H, Funakoshi-Tago M.
A 5-hydroxyoxindole derivative attenuates LPS-induced inflammatory responses by activating the p38-Nrf2 signaling axis.
Biochem. Pharmacol.
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Matsuura R, Kaji H, Tomioka A, Sato T, Narimatsu H, Moriwaki Y, Misawa H, Imai K, Tsuji S.
Identification of mesothelioma-specific sialylated epitope recognized with monoclonal antibody SKM9-2 in a mucin-like membrane protein HEG1.
Sci Rep
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PubMed ID: 30250045
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Kamiki H, Matsugo H, Kobayashi T, Ishida H, Takenaka-Uema A, Murakami S, Horimoto T.
A PB1-K577E Mutation in H9N2 Influenza Virus Increases Polymerase Activity and Pathogenicity in Mice.
Viruses
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PubMed ID: 30463209
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Saeki E, Yasuhira S, Shibazaki M, Tada H, Doita M, Masuda T, Maesawa C.
Involvement of C-terminal truncation mutation of kinesin-5 in resistance to kinesin-5 inhibitor.
PLoS ONE
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Xu P, Kai C, Kawasaki S, Kobayashi Y, Yamamoto K, Tsujikawa M, Hayashi R, Nishida K.
A New in Vitro Model of GDLD by Knocking Out TACSTD2 and Its Paralogous Gene EpCAM in Human Corneal Epithelial Cells.
Transl Vis Sci Technol
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Kandori S, Kojima T, Matsuoka T, Yoshino T, Sugiyama A, Nakamura E, Shimazui T, Funakoshi Y, Kanaho Y, Nishiyama H.
Phospholipase D2 promotes disease progression of renal cell carcinoma through the induction of angiogenin.
Cancer Sci.
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Hirose Y, Onishi T, Miura S, Hatazawa Y, Kamei Y.
Vitamin D Attenuates FOXO1-Target Atrophy Gene Expression in C2C12 Muscle Cells.
J. Nutr. Sci. Vitaminol.
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Miyagawa Y, Matsushita Y, Suzuki H, Komatsu M, Yoshimaru T, Kimura R, Yanai A, Honda J, Tangoku A, Sasa M, Miyoshi Y, Katagiri T.
Frequent downregulation of LRRC26 by epigenetic alterations is involved in the malignant progression of triple-negative breast cancer.
Int. J. Oncol.
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Kumeta M, Panina Y, Yamazaki H, Takeyasu K, Yoshimura SH.
N-terminal dual lipidation-coupled molecular targeting into the primary cilium.
Genes Cells
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Kato Y, Ninomiya K, Ohashi K, Tomida S, Makimoto G, Watanabe H, Kudo K, Matsumoto S, Umemura S, Goto K, Ichihara E, Ninomiya T, Kubo T, Sato A, Hotta K, Tabata M, Toyooka S, Maeda Y, Kiura K.
Combined effect of cabozantinib and gefitinib in crizotinib-resistant lung tumors harboring ROS1 fusions.
Cancer Sci.
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Ito S, Ueno A, Ueda T, Nakagawa H, Taniguchi H, Kayukawa N, Fujihara-Iwata A, Hongo F, Okihara K, Ukimura O.
CNPY2 inhibits MYLIP-mediated AR protein degradation in prostate cancer cells.
Oncotarget
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4465
Watanabe Y, Arai Y, Kawashita N, Ibrahim MS, Elgendy EM, Daidoji T, Kajikawa J, Hiramatsu H, Sriwilaijaroen N, Ono T, Takagi T, Takahashi K, Shioda T, Matsumoto K, Suzuki Y, Nakaya T.
Characterization of H5N1 Influenza Virus Quasispecies with Adaptive Hemagglutinin Mutations from Single-Virus Infections of Human Airway Cells.
J. Virol.
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A Split-Luciferase-Based Trimer Formation Assay as a High-throughput Screening Platform for Therapeutics in Alport Syndrome.
Cell Chem Biol
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Asuka Yoshida, Ryoko Kawabata, Tomoyuki Honda, Kouji Sakai, Yasushi Ami, Takemasa Sakaguchi, Takashi Irie
A Single Amino Acid Substitution Within the Paramyxovirus Sendai Virus Nucleoprotein Is a Critical Determinant for Production of Interferon-Beta-Inducing Copyback-Type Defective Interfering Genomes
J Virol
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Anti-tumor efficacy of a novel CLK inhibitor via targeting RNA splicing and MYC-dependent vulnerability
EMBO Mol Med
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Senga S, Kawaguchi K, Kobayashi N, Ando A, Fujii H.
A novel fatty acid-binding protein 5-estrogen-related receptor α signaling pathway promotes cell growth and energy metabolism in prostate cancer cells
Oncotarget
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9(60):31753-31770
PubMed ID: 30167092
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Iijima K, Kobayashi J, Ishizaka Y.
Structural alteration of DNA induced by viral protein R of HIV-1 triggers the DNA damage response
Retrovirology
2018
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PubMed ID: 29338752
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Kawabata Galbraith K, Fujishima K, Mizuno H, Lee SJ, Uemura T, Sakimura K, Mishina M, Watanabe N, Kengaku M.
MTSS1 Regulation of Actin-Nucleating Formin DAAM1 in Dendritic Filopodia Determines Final Dendritic Configuration of Purkinje Cells
Cell Rep
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Matsumoto N, Sekiya M, Tohyama K, Ishiyama-Matsuura E, Sun-Wada GH, Wada Y, Futai M, Nakanishi-Matsui M.
Essential Role of the a3 Isoform of V-ATPase in Secretory Lysosome Trafficking via Rab7 Recruitmen
Sci Rep
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Saito F, Hirayasu K, Satoh T, Wang CW, Lusingu J, Arimori T, Shida K, Palacpac NMQ, Itagaki S, Iwanaga S, Takashima E, Tsuboi T, Kohyama M, Suenaga T, Colonna M, Takagi J, Lavstsen T, Horii T, Arase H.
Immune evasion of Plasmodium falciparum by RIFIN via inhibitory receptors.
Nature
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Chung J, Aburaya S, Aoki W, Ueda M.
Molecular changes in appearance of a cancer cell among normal HEK293T cells.
J. Biosci. Bioeng.
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Takayama I, Tanabe H, Nishiyama T, Ito H, Amizuka N, Li M, Katsube KI, Kii I, Kudo A.
Periostin is required for matricellular localization of CCN3 in periodontal ligament of mice.
J Cell Commun Signal
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Matsui T, Hori A, Hamako J, Matsushita F, Ozeki Y, Sakurai Y, Hayakawa M, Matsumoto M, Fujimura Y.
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EPSIN 3, A Novel p53 Target, Regulates the Apoptotic Pathway and Gastric Carcinogenesis.
Neoplasia
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A Key Regulator of Cell Adhesion: Identification and Characterization of Important N-Glycosylation Sites on Integrin α5 for Cell Migration.
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Kawaguchi Y, Nariki H, Kawamoto N, Kanehiro Y, Miyazaki S, Suzuki M, Magari M, Tokumitsu H, Kanayama N.
SRSF1-3 contributes to diversification of the immunoglobulin variable region gene by promoting accumulation of AID in the nucleus.
Biochem. Biophys. Res. Commun.
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Wada Y, Orba Y, Sasaki M, Kobayashi S, Carr MJ, Nobori H, Sato A, Hall WW, Sawa H.
Discovery of a novel antiviral agent targeting the nonstructural protein 4 (nsP4) of chikungunya virus.
Virology
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Substrate specificity of TOR complex 2 is determined by a ubiquitin-fold domain of the Sin1 subunit.
Elife
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Guo L, Elcioglu NH, Mizumoto S, Wang Z, Noyan B, Albayrak HM, Yamada S, Matsumoto N, Miyake N, Nishimura G, Ikegawa S.
Identification of biallelic EXTL3 mutations in a novel type of spondylo-epi-metaphyseal dysplasia.
J. Hum. Genet.
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A novel method to generate single-cell-derived cancer-associated fibroblast clones.
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Goyal S, Suzuki T, Li JR, Maeda S, Kishima M, Nishimura H, Shimizu Y, Suzuki H.
RUNX1 induces DNA replication independent active DNA demethylation at SPI1 regulatory regions.
BMC Mol. Biol.
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Hiwa R, Ohmura K, Arase N, Jin H, Hirayasu K, Kohyama M, Suenaga T, Saito F, Terao C, Atsumi T, Iwatani H, Mimori T, Arase H.
Myeloperoxidase/HLA Class II Complexes Recognized by Autoantibodies in Microscopic Polyangiitis.
Arthritis Rheumatol
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Takahashi Y, Tanikawa C, Miyamoto T, Hirata M, Wang G, Ueda K, Komatsu T, Matsuda K.
Regulation of tubular recycling endosome biogenesis by the p53-MICALL1 pathway.
Int. J. Oncol.
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Ishii T, Homma K, Mano A, Akagi T, Shigematsu Y, Shimoda Y, Inoue H, Kakinuma Y, Kaneda M.
Novel channel-mediated choline transport in cholinergic neurons of the mouse retina.
J. Neurophysiol.
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Morita K, Maeda S, Suzuki K, Kiyose H, Taniguchi J, Liu PP, Sugiyama H, Adachi S, Kamikubo Y.
Paradoxical enhancement of leukemogenesis in acute myeloid leukemia with moderately attenuated RUNX1 expressions.
Blood Adv
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Structural analysis of the STAT1:STAT2 heterodimer revealed the mechanism of Sendai virus C protein-mediated blockade of type 1 interferon signaling.
J. Biol. Chem.
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Hirano K, Namihira M.
FAD influx enhances neuronal differentiation of human neural stem cells by facilitating nuclear localization of LSD1.
FEBS Open Bio
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Yamamura T, Nozu K, Miyoshi Y, Nakanishi K, Fujimura J, Horinouchi T, Minamikawa S, Mori N, Fujimaru R, Nakanishi K, Ninchoji T, Kaito H, Mariko TI, Morioka I, Matsuo M, Iijima K.
An in vitro splicing assay reveals the pathogenicity of a novel intronic variant in ATP6V0A4 for autosomal recessive distal renal tubular acidosis.
BMC Nephrol
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Suzuki T, Maeda S, Furuhata E, Shimizu Y, Nishimura H, Kishima M, Suzuki H.
A screening system to identify transcription factors that induce binding site-directed DNA demethylation.
Epigenetics Chromatin
2017
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Shichita T, Ito M, Morita R, Komai K, Noguchi Y, Ooboshi H, Koshida R, Takahashi S, Kodama T, Yoshimura A.
MAFB prevents excess inflammation after ischemic stroke by accelerating clearance of damage signals through MSR1.
Nat. Med.
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Meng H, Yamashita C, Shiba-Fukushima K, Inoshita T, Funayama M, Sato S, Hatta T, Natsume T, Umitsu M, Takagi J, Imai Y, Hattori N.
Loss of Parkinson's disease-associated protein CHCHD2 affects mitochondrial crista structure and destabilizes cytochrome c.
Nat Commun
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Nagasato AI, Yamashita H, Matsuo M, Ueda K, Kioka N.
The distribution of vinculin to lipid rafts plays an important role in sensing stiffness of extracellular matrix.
Biosci Biotechnol Biochem
2017
81(6):1136-1147
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Jaerin Sohn, Megumu Takahashi, Shinichiro Okamoto, Yoko Ishida, Takahiro Furuta, Hiroyuki Hioki
A Single Vector Platform for High-Level Gene Transduction of Central Neurons: Adeno-Associated Virus Vector Equipped With the Tet-Off System
PLoS One
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12(1):e0169611
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Shigenori Inagaki, Hidekazu Tsutsui, Kazushi Suzuki, Masakazu Agetsuma, Yoshiyuki Arai, Yuka Jinno, Guirong Bai, Matthew J Daniels, Yasushi Okamura, Tomoki Matsuda, Takeharu Nagai
Genetically encoded bioluminescent voltage indicator for multi-purpose use in wide range of bioimaging
Sci Rep
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7:42398
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Nakano T, Kanai Y, Amano Y, Yoshimoto T, Matsubara D, Shibano T, Tamura T, Oguni S, Katashiba S, Ito T, Murakami Y, Fukayama M, Murakami T, Endo S, Niki T.
Establishment of highly metastatic KRAS mutant lung cancer cell sublines in long-term three-dimensional low attachment cultures
PLoS Onec
2017
12(8):e0181342
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Fujitani M, Zhang S, Fujiki R, Fujihara Y, Yamashita T.
A chromosome 16p13.11 microduplication causes hyperactivity through dysregulation of miR-484/protocadherin-19 signaling
Mol Psychiatry
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22(3):364-374
PubMed ID: 27378146
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14236
Okumura N, Kitahara M, Okuda H, Hashimoto K, Ueda E, Nakahara M, Kinoshita S, Young RD, Quantock AJ, Tourtas T, Schlötzer-Schrehardt U, Kruse F, Koizumi N.
Sustained Activation of the Unfolded Protein Response Induces Cell Death in Fuchs' Endothelial Corneal Dystrophy
Invest Ophthalmol Vis Sci
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58(9):3697-3707
PubMed ID: 28727885
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Senga Y, Imamura H, Miyafusa T, Watanabe H, Honda S.
AlphaScreen-based homogeneous assay using a pair of 25-residue artificial proteins for high-throughput analysis of non-native IgG
Sci Rep
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7(1):12466
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Endo H, Tanaka S, Imamura K, Adegawa S, Kikuta S, Sato R.
Cry toxin specificities of insect ABCC transporters closely related to lepidopteran ABCC2 transporters
Peptides
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Kano D, Nakagami Y, Kurihara H, Hosokawa S, Zenda S, Kusumoto M, Fujii H, Kaneta T, Saito S, Uesawa Y, Kagaya H.
Development of a double-stranded siRNA labelling method by using 99m Tc and single photon emission computed tomography imaging
J Drug Target
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25(2):172-178
PubMed ID: 27588821
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Tsukamoto T, Chiba Y, Wakamori M, Yamada T, Tsunogae S, Cho Y, Sakakibara R, Imazu T, Tokoro S, Satake Y, Adachi M, Nishikawa T, Yotsu-Yamashita M, Konoki K.
Differential binding of tetrodotoxin and its derivatives to voltage-sensitive sodium channel subtypes (Na v 1.1 to Na v 1.7)
Br J Pharmacol
2017
174(21):3881-3892
PubMed ID: 28832970
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Wu DC, Wang SSW, Liu CJ, Wuputra K, Kato K, Lee YL, Lin YC, Tsai MH, Ku CC, Lin WH, Wang SW, Kishikawa S, Noguchi M, Wu CC, Chen YT, Chai CY, Lin CS, Kuo KK, Yang YH, Miyoshi H, Nakamura Y, Saito S, Nagata K, Lin CS, Yokoyama KK.
Reprogramming Antagonizes the Oncogenicity of HOXA13-Long Noncoding RNA HOTTIP Axis in Gastric Cancer Cells
Stem Cells
2017
35(10):2115-2128
PubMed ID: 28782268
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14749
Kikuta S, Watanabe SJ, Sato R, Gusev O, Nesmelov A, Sogame Y, Cornette R, Kikawada T.
Towards water-free biobanks: long-term dry-preservation at room temperature of desiccation-sensitive enzyme luciferase in air-dried insect cells
Sci Rep
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7(1):6540
PubMed ID: 28747745
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Kobayashi JI, Hirasawa H, Ozawa T, Ozawa T, Takeda H, Fujimori Y, Nakanishi O, Kamada N, Ikeda T.
Synthesis and optimization of novel α-phenylglycinamides as selective TRPM8 antagonists
Bioorg Med Chem
2017
25(2):727-742
PubMed ID: 27964995
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14767
Elgendy EM, Arai Y, Kawashita N, Daidoji T, Takagi T, Ibrahim MS, Nakaya T, Watanabe Y.
Identification of polymerase gene mutations that affect viral replication in H5N1 influenza viruses isolated from pigeons
J Gen Virol
2017
98(1):6-17
PubMed ID: 27926816
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14777
Shigenori Inagaki, Masakazu Agetsuma, Shinya Ohara, Toshio Iijima, Tetsuichi Wazawa, Yoshiyuki Arai, Takeharu Nagai
In vivo brain activity imaging of interactively locomoting mice
bioRxiv
2017
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16633
Khedgikar V, Abbruzzese G, Mathavan K, Szydlo H, Cousin H, Alfandari D.
Dual control of pcdh8l/PCNS expression and function in Xenopus laevis neural crest cells by adam13/33 via the transcription factors tfap2α and arid3a
Elife
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Suzuki K, Kimura T, Shinoda H, Bai G, Daniels MJ, Arai Y, Nakano M, Nagai T.
Five colour variants of bright luminescent protein for real-time multicolour bioimaging.
Nat Commun
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Funato H, Miyoshi C, Fujiyama T, Kanda T, Sato M, Wang Z, Ma J, Nakane S, Tomita J, Ikkyu A, Kakizaki M, Hotta-Hirashima N, Kanno S, Komiya H, Asano F, Honda T, Kim SJ, Harano K, Muramoto H, Yonezawa T, Mizuno S, Miyazaki S, Connor L, Kumar V, Miura I, Suzuki T, Watanabe A, Abe M, Sugiyama F, Takahashi S, Sakimura K, Hayashi Y, Liu Q, Kume K, Wakana S, Takahashi JS, Yanagisawa M.
Forward-genetics analysis of sleep in randomly mutagenized mice.
Nature
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Kanda S, Yanagitani K, Yokota Y, Esaki Y, Kohno K.
Autonomous translational pausing is required for XBP1u mRNA recruitment to the ER via the SRP pathway.
Proc. Natl. Acad. Sci. U.S.A.
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Hashimoto T, Horikawa DD, Saito Y, Kuwahara H, Kozuka-Hata H, Shin-I T, Minakuchi Y, Ohishi K, Motoyama A, Aizu T, Enomoto A, Kondo K, Tanaka S, Hara Y, Koshikawa S, Sagara H, Miura T, Yokobori S, Miyagawa K, Suzuki Y, Kubo T, Oyama M, Kohara Y, Fujiyama A, Arakawa K, Katayama T, Toyoda A, Kunieda T.
Extremotolerant tardigrade genome and improved radiotolerance of human cultured cells by tardigrade-unique protein.
Nat Commun
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Morita S, Noguchi H, Horii T, Nakabayashi K, Kimura M, Okamura K, Sakai A, Nakashima H, Hata K, Nakashima K, Hatada I.
Targeted DNA demethylation in vivo using dCas9-peptide repeat and scFv-TET1 catalytic domain fusions.
Nat. Biotechnol.
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Kataoka K, Shiraishi Y, Takeda Y, Sakata S, Matsumoto M, Nagano S, Maeda T, Nagata Y, Kitanaka A, Mizuno S, Tanaka H, Chiba K, Ito S, Watatani Y, Kakiuchi N, Suzuki H, Yoshizato T, Yoshida K, Sanada M, Itonaga H, Imaizumi Y, Totoki Y, Munakata W, Nakamura H, Hama N, Shide K, Kubuki Y, Hidaka T, Kameda T, Masuda K, Minato N, Kashiwase K, Izutsu K, Takaori-Kondo A, Miyazaki Y, Takahashi S, Shibata T, Kawamoto H, Akatsuka Y, Shimoda K, Takeuchi K, Seya T, Miyano S, Ogawa S.
Aberrant PD-L1 expression through 3'-UTR disruption in multiple cancers.
Nature
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Ichijo Y, Mochimaru Y, Azuma M, Satou K, Negishi J, Nakakura T, Oshima N, Mogi C, Sato K, Matsuda K, Okajima F, Tomura H.
Two zebrafish G2A homologs activate multiple intracellular signaling pathways in acidic environment.
Biochem. Biophys. Res. Commun.
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Kikuta S, Hou BH, Sato R, Frommer WB, Kikawada T.
FRET sensor-based quantification of intracellular trehalose in mammalian cells.
Biosci. Biotechnol. Biochem.
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Hagiwara A, Ogiwara K, Takahashi T.
Expression of Membrane Progestin Receptors (mPRs) in Granulosa Cells of Medaka Preovulatory Follicles.
Zool. Sci.
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Koguchi T, Tanikawa C, Mori J, Kojima Y, Matsuda K.
Regulation of myo-inositol biosynthesis by p53-ISYNA1 pathway.
Int. J. Oncol.
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Tsuchiya M, Niwa Y, Simizu S.
N-glycosylation of R-spondin1 at Asn137 negatively regulates its secretion and Wnt/β-catenin signaling-enhancing activity.
Oncol Lett
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Tanaka H, Fujiwara H, Ochi F, Tanimoto K, Casey N, Okamoto S, Mineno J, Kuzushima K, Shiku H, Sugiyama T, Barrett AJ, Yasukawa M.
Development of Engineered T Cells Expressing a Chimeric CD16-CD3ζ Receptor to Improve the Clinical Efficacy of Mogamulizumab Therapy Against Adult T-Cell Leukemia.
Clin. Cancer Res.
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Hirayasu K, Saito F, Suenaga T, Shida K, Arase N, Oikawa K, Yamaoka T, Murota H, Chibana H, Nakagawa I, Kubori T, Nagai H, Nakamaru Y, Katayama I, Colonna M, Arase H.
Microbially cleaved immunoglobulins are sensed by the innate immune receptor LILRA2.
Nat Microbiol
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Khanom R, Nguyen CT, Kayamori K, Zhao X, Morita K, Miki Y, Katsube K, Yamaguchi A, Sakamoto K.
Keratin 17 Is Induced in Oral Cancer and Facilitates Tumor Growth.
PLoS ONE
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Yamaura K, Kiyonaka S, Numata T, Inoue R, Hamachi I.
Discovery of allosteric modulators for GABAA receptors by ligand-directed chemistry.
Nat. Chem. Biol.
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Development of Genome Engineering Tools from Plant-Specific PPR Proteins Using Animal Cultured Cells.
Methods Mol. Biol.
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Kondoh Y, Honda K, Hiranuma S, Hayashi T, Shimizu T, Watanabe N, Osada H.
Comparative chemical array screening for p38γ/δ MAPK inhibitors using a single gatekeeper residue difference between p38α/β and p38γ/δ.
Sci Rep
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Hazawa M, Yasuda T, Saotome-Nakamura A, Tomiyama K, Obara C, Goto T, Tajima K.
Intra- and extracellular plasminogen activator inhibitor-1 regulate effect of vitronectin against radiation-induced endothelial cell death.
Vascul. Pharmacol.
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Hang Q, Isaji T, Hou S, Zhou Y, Fukuda T, Gu J.
N-Glycosylation of integrin α5 acts as a switch for EGFR-mediated complex formation of integrin α5β1 to α6β4.
Sci Rep
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Kurita K, Maeda M, Mansour MA, Kokuryo T, Uehara K, Yokoyama Y, Nagino M, Hamaguchi M, Senga T.
TRIP13 is expressed in colorectal cancer and promotes cancer cell invasion.
Oncol Lett
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DAAM1 stabilizes epithelial junctions by restraining WAVE complex-dependent lateral membrane motility.
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Interaction of cytokeratin 19 head domain and HER2 in the cytoplasm leads to activation of HER2-Erk pathway.
Sci Rep
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Hirayama S, Hori Y, Benedek Z, Suzuki T, Kikuchi K.
Fluorogenic probes reveal a role of GLUT4 N-glycosylation in intracellular trafficking.
Nat. Chem. Biol.
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Importance of membrane-proximal N-glycosylation on integrin β1 in its activation and complex formation.
FASEB J.
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Kung-Kai Kuo, King-Teh Lee, Ker-Kong Chen, Ya-Han Yang, Ying-Chu Lin, Ming-Ho Tsai, Kenly Wuputra, Yen-Liang Lee, Chia-Chen Ku, Hiroyuki Miyoshi, Yukio Nakamura, Shigeo Saito, Chun-Chieh Wu, Chee-Yin Chai, Richard Eckner, Chen-Lung Steve Lin, Sophie S-W Wang, Deng-Chyang Wu, Chang-Shen Lin, Kazunari K Yokoyama
Positive Feedback Loop of OCT4 and c-JUN Expedites Cancer Stemness in Liver Cancer
Stem Cells
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Elmansuri AZ, Tanino MA, Mahabir R, Wang L, Kimura T, Nishihara H, Kinoshita I, Dosaka-Akita H, Tsuda M, Tanaka S.
Novel signaling collaboration between TGF-β and adaptor protein Crk facilitates EMT in human lung cancer
Oncotarget
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7(19):27094-107
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Mori J, Tanikawa C, Funauchi Y, Lo PH, Nakamura Y, Matsuda K.
Cystatin C as a p53-inducible apoptotic mediator that regulates cathepsin L activity
Cancer Sci
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Lu J, Isaji T, Im S, Fukuda T, Kameyama A, Gu J.
Expression of N-Acetylglucosaminyltransferase III Suppresses α2,3-Sialylation, and Its Distinctive Functions in Cell Migration Are Attributed to α2,6-Sialylation Levels
J Biol Chem
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Sohn J, Okamoto S, Kataoka N, Kaneko T, Nakamura K, Hioki H.
Differential Inputs to the Perisomatic and Distal-Dendritic Compartments of VIP-Positive Neurons in Layer 2/3 of the Mouse Barrel Cortex
Front Neuroanat
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Ryuzono S, Takase R, Oishi K, Ikeda A, Chigwechokha PK, Funahashi A, Komatsu M, Miyagi T, Shiozaki K.
Lysosomal localization of Japanese medaka (Oryzias latipes) Neu1 sialidase and its highly conserved enzymatic profiles with human
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Obayashi M, Yoshida M, Tsunematsu T, Ogawa I, Sasahira T, Kuniyasu H, Imoto I, Abiko Y, Xu D, Fukunaga S, Tahara H, Kudo Y, Nagao T, Takata T.
microRNA-203 suppresses invasion and epithelial-mesenchymal transition induction via targeting NUAK1 in head and neck cancer
Oncotarget
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7(7):8223-39
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12941
Saho S, Satoh H, Kondo E, Inoue Y, Yamauchi A, Murata H, Kinoshita R, Yamamoto KI, Futami J, Putranto EW, Ruma IM, Sumardika IW, Youyi C, Suzawa K, Yamamoto H, Soh J, Tomida S, Sakaguchi Y, Saito K, Iioka H, Huh NH, Toyooka S, Sakaguchi M.
Active Secretion of Dimerized S100A11 Induced by the Peroxisome in Mesothelioma Cells
Cancer Microenviron
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9(2-3):93-105
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Miyake T, Kumasawa K, Sato N, Takiuchi T, Nakamura H, Kimura T.
Soluble VEGF receptor 1 (sFLT1) induces non-apoptotic death in ovarian and colorectal cancer cells
Sci Rep
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6:24853
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Wang SS, Wuputra K, Liu CJ, Lin YC, Chen YT, Chai CY, Lin CS, Kuo KK, Tsai MH, Wang SW, Chen KK, Miyoshi H, Nakamura Y, Saito S, Hanafusa T, Wu DC, Lin CS, Yokoyama KK.
Oncogenic function of the homeobox A13-long noncoding RNA HOTTIP-insulin growth factor-binding protein 3 axis in human gastric cancer
Oncotarget
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7(24):36049-36064
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Yasuhira S, Shibazaki M, Nishiya M, Maesawa C.
Paclitaxel-induced aberrant mitosis and mitotic slippage efficiently lead to proliferative death irrespective of canonical apoptosis and p53
Cell Cycle
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15(23):3268-3277
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Sakamoto Y, Kanatsu J, Toh M, Naka A, Kondo K, Iida K.
The Dietary Isoflavone Daidzein Reduces Expression of Pro-Inflammatory Genes through PPARα/γ and JNK Pathways in Adipocyte and Macrophage Co-Cultures
PLoS One
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Hou S, Isaji T, Hang Q, Im S, Fukuda T, Gu J.
Distinct effects of β1 integrin on cell proliferation and cellular signaling in MDA-MB-231 breast cancer cells
Sci Rep
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Sakuma T, Nakade S, Sakane Y, Suzuki KT, Yamamoto T.
MMEJ-assisted gene knock-in using TALENs and CRISPR-Cas9 with the PITCh systems
Nat Protoc
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Johmura Y, Sun J, Kitagawa K, Nakanishi K, Kuno T, Naiki-Ito A, Sawada Y, Miyamoto T, Okabe A, Aburatani H, Li S, Miyoshi I, Takahashi S, Kitagawa M, Nakanishi M.
SCF(Fbxo22)-KDM4A targets methylated p53 for degradation and regulates senescence
Nat Commun
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Kikuta S, Endo H, Tomita N, Takada T, Morita C, Asaoka K, Sato R.
Characterization of a ligand-gated cation channel based on an inositol receptor in the silkworm, Bombyx mori
Insect Biochem Mol Biol
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74:12-20
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Tetsuo Koshizuka, Keiichiro Tanaka, Tatsuo Suzutani
Degradation of host ubiquitin E3 ligase Itch by human cytomegalovirus UL42
Journal of General Virology
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Mang D, Shu M, Endo H, Yoshizawa Y, Nagata S, Kikuta S, Sato R.
Expression of a sugar clade gustatory receptor, BmGr6, in the oral sensory organs, midgut, and central nervous system of larvae of the silkworm Bombyx mori
Insect Biochem Mol Biol
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Hang Q, Isaji T, Hou S, Im S, Fukuda T, Gu J.
Integrin α5 Suppresses the Phosphorylation of Epidermal Growth Factor Receptor and Its Cellular Signaling of Cell Proliferation via N-Glycosylation.
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Kataoka K, Nagata Y, Kitanaka A, Shiraishi Y, Shimamura T, Yasunaga J, Totoki Y, Chiba K, Sato-Otsubo A, Nagae G, Ishii R, Muto S, Kotani S, Watatani Y, Takeda J, Sanada M, Tanaka H, Suzuki H, Sato Y, Shiozawa Y, Yoshizato T, Yoshida K, Makishima H, Iwanaga M, Ma G, Nosaka K, Hishizawa M, Itonaga H, Imaizumi Y, Munakata W, Ogasawara H, Sato T, Sasai K, Muramoto K, Penova M, Kawaguchi T, Nakamura H, Hama N, Shide K, Kubuki Y, Hidaka T, Kameda T, Nakamaki T, Ishiyama K, Miyawaki S, Yoon SS, Tobinai K, Miyazaki Y, Takaori-Kondo A, Matsuda F, Takeuchi K, Nureki O, Aburatani H, Watanabe T, Shibata T, Matsuoka M, Miyano S, Shimoda K, Ogawa S.
Integrated molecular analysis of adult T cell leukemia/lymphoma.
Nat. Genet.
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Aoki N, Yamaguchi S, Kitajima T, Takehara A, Katagiri-Nakagawa S, Matsui R, Watanabe D, Matsushima T, Homma KJ.
Critical role of the neural pathway from the intermediate medial mesopallium to the intermediate hyperpallium apicale in filial imprinting of domestic chicks (Gallus gallus domesticus).
Neuroscience
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Okumura N, Minamiyama R, Ho LT, Kay EP, Kawasaki S, Tourtas T, Schlotzer-Schrehardt U, Kruse FE, Young RD, Quantock AJ, Kinoshita S, Koizumi N.
Involvement of ZEB1 and Snail1 in excessive production of extracellular matrix in Fuchs endothelial corneal dystrophy.
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Ichikawa T, Nakahata S, Fujii M, Iha H, Morishita K.
Loss of NDRG2 enhanced activation of the NF-κB pathway by PTEN and NIK phosphorylation for ATL and other cancer development.
Sci Rep
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The loss of NDRG2 expression improves depressive behavior through increased phosphorylation of GSK3β.
Cell. Signal.
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Tohmonda T, Yoda M, Iwawaki T, Matsumoto M, Nakamura M, Mikoshiba K, Toyama Y, Horiuchi K.
IRE1α/XBP1-mediated branch of the unfolded protein response regulates osteoclastogenesis.
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Saraiva-Pava K, Navabi N, Skoog EC, Linden SK, Oleastro M, Roxo-Rosa M.
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Kimura T, Endo S, Inui M, Saitoh S, Miyake K, Takai T.
Endoplasmic Protein Nogo-B (RTN4-B) Interacts with GRAMD4 and Regulates TLR9-Mediated Innate Immune Responses.
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Convergence of Lemniscal and Local Excitatory Inputs on Large GABAergic Tectothalamic Neurons.
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Upregulation of Runt-Related Transcription Factor-2 Through CCAAT Enhancer Binding Protein-β Signaling Pathway in Microglial BV-2 Cells Exposed to ATP.
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Ebina H, Kanemura Y, Misawa N, Sakuma T, Kobayashi T, Yamamoto T, Koyanagi Y.
A high excision potential of TALENs for integrated DNA of HIV-based lentiviral vector.
PLoS ONE
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Masuda K, Chiyoda T, Sugiyama N, Segura-Cabrera A, Kabe Y, Ueki A, Banno K, Suematsu M, Aoki D, Ishihama Y, Saya H, Kuninaka S.
LATS1 and LATS2 phosphorylate CDC26 to modulate assembly of the tetratricopeptide repeat subcomplex of APC/C.
PLoS ONE
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Mochimaru Y, Azuma M, Oshima N, Ichijo Y, Satou K, Matsuda K, Asaoka Y, Nishina H, Nakakura T, Mogi C, Sato K, Okajima F, Tomura H.
Extracellular acidification activates ovarian cancer G-protein-coupled receptor 1 and GPR4 homologs of zebra fish.
Biochem. Biophys. Res. Commun.
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Nakamura R, Oyama T, Tajiri R, Mizokami A, Namiki M, Nakamoto M, Ooi A.
Expression and regulatory effects on cancer cell behavior of NELL1 and NELL2 in human renal cell carcinoma.
Cancer Sci
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106(5):656-64
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Tadahiro Suenaga, Maki Matsumoto, Fuminori Arisawa, Masako Kohyama, Kouyuki Hirayasu, Yasuko Mori, Hisashi Arase
Sialic Acids on Varicella-Zoster Virus Glycoprotein B Are Required for Cell-Cell Fusion
J Biol Chem
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290(32):19833-43
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Bill A, Gutierrez A, Kulkarni S, Kemp C, Bonenfant D, Voshol H, Duvvuri U, Gaither LA.
ANO1/TMEM16A interacts with EGFR and correlates with sensitivity to EGFR-targeting therapy in head and neck cancer
Oncotarget
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6(11):9173-88
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Tanaka S, Tanaka J, Miwa Y, Horikawa DD, Katayama T, Arakawa K, Toyoda A, Kubo T, Kunieda T.
Novel mitochondria-targeted heat-soluble proteins identified in the anhydrobiotic Tardigrade improve osmotic tolerance of human cells
PLoS One
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Shinmyo Y, Asrafuzzaman Riyadh M, Ahmed G, Bin Naser I, Hossain M, Takebayashi H, Kawasaki H, Ohta K, Tanaka H.
Draxin from neocortical neurons controls the guidance of thalamocortical projections into the neocortex
Nat Commun
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Suzuki Y, Kiyokage E, Sohn J, Hioki H, Toida K.
Structural basis for serotonergic regulation of neural circuits in the mouse olfactory bulb
J Comp Neurol
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523(2):262-80
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Ohishi K, Toume K, Arai MA, Koyano T, Kowithayakorn T, Mizoguchi T, Itoh M, Ishibashi M.
9-Hydroxycanthin-6-one, a β-Carboline Alkaloid from Eurycoma longifolia, Is the First Wnt Signal Inhibitor through Activation of Glycogen Synthase Kinase 3β without Depending on Casein Kinase 1α
J Nat Prod
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Wakimoto T, Uchida K, Mimura K, Kanagawa T, Mehandjiev TR, Aoshima H, Kokubo K, Mitsuda N, Yoshioka Y, Tsutsumi Y, Kimura T, Yanagihara I.
Hydroxylated fullerene: a potential antiinflammatory and antioxidant agent for preventing mouse preterm birth
Am J Obstet Gynecol
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213(5):708.e1-9
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Yamanishi M, Narazaki H, Asano T.
Melatonin overcomes resistance to clofarabine in two leukemic cell lines by increased expression of deoxycytidine kinase
Exp Hematol
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Konoki K, Suga Y, Fuwa H, Yotsu-Yamashita M, Sasaki M.
Evaluation of gambierol and its analogs for their inhibition of human Kv1.2 and cytotoxicity
Bioorg Med Chem Lett
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7579
Suzuki-Nakagawa C, Nishimura M, Tsukamoto T, Aoyama S, Ebihara A, Suzuki F, Nakagawa T.
Participation of the extracellular domain in (pro)renin receptor dimerization.
Biochem. Biophys. Res. Commun.
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444:461-6
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Saito K, Sakaguchi M, Iioka H, Matsui M, Nakanishi H, Huh NH, Kondo E.
Coxsackie and adenovirus receptor is a critical regulator for the survival and growth of oral squamous carcinoma cells.
Oncogene
2014
33(10):1274-86
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14940
Okumura N, Hirano H, Numata R, Nakahara M, Ueno M, Hamuro J, Kinoshita S, Koizumi N.
Cell surface markers of functional phenotypic corneal endothelial cells
Invest Ophthalmol Vis Sci
2014
55(11):7610-8
PubMed ID: 25389199
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15805
Murakami-Tonami Y, Kishida S, Takeuchi I, Katou Y, Maris JM, Ichikawa H, Kondo Y, Sekido Y, Shirahige K, Murakami H, Kadomatsu K.
Inactivation of SMC2 shows a synergistic lethal response in MYCN-amplified neuroblastoma cells
Cell Cycle
2014
13(7):1115-31
PubMed ID: 24553121
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15812
Yamashita H, Ichikawa T, Matsuyama D, Kimura Y, Ueda K, Craig SW, Harada I, Kioka N.
The role of the interaction of the vinculin proline-rich linker region with vinexin α in sensing the stiffness of the extracellular matrix
J Cell Sci
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127(Pt 9):1875-86
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15829
Miyagawa-Yamaguchi A, Kotani N, Honke K.
Expressed glycosylphosphatidylinositol-anchored horseradish peroxidase identifies co-clustering molecules in individual lipid raft domains
PLoS One
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9(3):e93054
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Lu J, Isaji T, Im S, Fukuda T, Hashii N, Takakura D, Kawasaki N, Gu J.
β-Galactoside α2,6-sialyltranferase 1 promotes transforming growth factor-β-mediated epithelial-mesenchymal transition
J Biol Chem
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289(50):34627-41
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17086
Ishikawa F, Kaneko E, Sugimoto T, Ishijima T, Wakamatsu M, Yuasa A, Sampei R, Mori K, Nose K, Shibanuma M.
A mitochondrial thioredoxin-sensitive mechanism regulates TGF-β-mediated gene expression associated with epithelial-mesenchymal transition
Biochem Biophys Res Commun
2014
443(3):821-7
PubMed ID: 24342608
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17090
Park HY, Toume K, Arai MA, Sadhu SK, Ahmed F, Ishibashi M.
Calotropin: a cardenolide from calotropis gigantea that inhibits Wnt signaling by increasing casein kinase 1α in colon cancer cells
Chembiochem
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Takano M, Kanoh A, Amako K, Otani M, Sano K, Kanazawa-Hamada M, Matsuyama S.
Nuclear localization of bradykinin B(2) receptors reflects binding to the nuclear envelope protein lamin C
Eur J Pharmacol
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723:507-14
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Ohnishi H, Sasaki H, Nakamura Y, Kato S, Ando K, Narimatsu H, Tachibana K.
Regulation of cell shape and adhesion by CD34
Cell Adh Migr
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Kon A, Shih LY, Minamino M, Sanada M, Shiraishi Y, Nagata Y, Yoshida K, Okuno Y, Bando M, Nakato R, Ishikawa S, Sato-Otsubo A, Nagae G, Nishimoto A, Haferlach C, Nowak D, Sato Y, Alpermann T, Nagasaki M, Shimamura T, Tanaka H, Chiba K, Yamamoto R, Yamaguchi T, Otsu M, Obara N, Sakata-Yanagimoto M, Nakamaki T, Ishiyama K, Nolte F, Hofmann WK, Miyawaki S, Chiba S, Mori H, Nakauchi H, Koeffler HP, Aburatani H, Haferlach T, Shirahige K, Miyano S, Ogawa S.
Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms
Nat Genet
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Takahashi K, Orba Y, Kimura T, Wang L, Kohsaka S, Tsuda M, Tanino M, Nishihara H, Nagashima K, Sawa H, Tanaka S.
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Jpn J Infect Dis
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Koyama T, Sun B, Tokunaga K, Tatsumi M, Ishizaka Y.
DNA damage enhances integration of HIV-1 into macrophages by overcoming integrase inhibition
Retrovirology
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Yaguchi M, Ohashi Y, Tsubota T, Sato A, Koyano KW, Wang N, Miyashita Y.
Characterization of the properties of seven promoters in the motor cortex of rats and monkeys after lentiviral vector-mediated gene transfer
Hum Gene Ther Methods
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24(6):333-44
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16888
Haruta M, Tomita Y, Yuno A, Matsumura K, Ikeda T, Takamatsu K, Haga E, Koba C, Nishimura Y, Senju S.
TAP-deficient human iPS cell-derived myeloid cell lines as unlimited cell source for dendritic cell-like antigen-presenting cells
Gene Ther
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Matsushita N, Matsushita S, Hirakawa S, Higashiyama S.
Doxycycline-dependent inducible and reversible RNA interference mediated by a single lentivirus vector
Biosci Biotechnol Biochem
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Ayami Yamaguchi 1, Sae Tanaka, Shiho Yamaguchi, Hirokazu Kuwahara, Chizuko Takamura, Shinobu Imajoh-Ohmi, Daiki D Horikawa, Atsushi Toyoda, Toshiaki Katayama, Kazuharu Arakawa, Asao Fujiyama, Takeo Kubo, Takekazu Kunieda
Two Novel Heat-Soluble Protein Families Abundantly Expressed in an Anhydrobiotic Tardigrade
PLoS One
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Nishimura T, Honda H, Takeichi M.
Planar cell polarity links axes of spatial dynamics in neural-tube closure
Cell
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Proliferation of rat small hepatocytes requires follistatin expression
J Cell Physiol
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Li Y, Mitsuhashi S, Ikejo M, Miura N, Kawamura T, Hamakubo T, Ubukata M.
Relationship between ATM and ribosomal protein S6 revealed by the chemical inhibition of Ser/Thr protein phosphatase type 1
Biosci Biotechnol Biochem
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Optogenetic inhibition of Purkinje cell activity reveals cerebellar control of blood pressure during postural alterations in anesthetized rats
Neuroscience .
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Ohue Y, Eikawa S, Okazaki N, Mizote Y, Isobe M, Uenaka A, Fukuda M, Old LJ, Oka M, Nakayama E.
Spontaneous antibody, and CD4 and CD8 T-cell responses against XAGE-1b (GAGED2a) in non-small cell lung cancer patients.
Int. J. Cancer
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Sakaguchi T, Irie T, Kuwayama M, Ueno T, Yoshida A, Kawabata R.
Analysis of interaction of Sendai virus V protein and melanoma differentiation-associated gene 5.
Microbiol. Immunol.
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Jin ZB, Okamoto S, Osakada F, Homma K, Assawachananont J, Hirami Y, Iwata T, Takahashi M.
Modeling retinal degeneration using patient-specific induced pluripotent stem cells.
PLoS ONE
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Narukawa M, Noga C, Ueno Y, Sato T, Misaka T, Watanabe T.
Evaluation of the bitterness of green tea catechins by a cell-based assay with the human bitter taste receptor hTAS2R39.
Biochem. Biophys. Res. Commun.
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Ayako Kataoka, Yui Koga, Ayumi Uesugi, Hidetoshi Tozaki-Saitoh, Makoto Tsuda, Kazuhide Inoue
Involvement of vasodilator-stimulated phosphoprotein in UDP-induced microglial actin aggregation via PKC- and Rho-dependent pathways
Purinergic Signal
2011
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Sasaki M, Kawahara K, Nishio M, Mimori K, Kogo R, Hamada K, Itoh B, Wang J, Komatsu Y, Yang YR, Hikasa H, Horie Y, Yamashita T, Kamijo T, Zhang Y, Zhu Y, Prives C, Nakano T, Mak TW, Sasaki T, Maehama T, Mori M, Suzuki A.
Regulation of the MDM2-P53 pathway and tumor growth by PICT1 via nucleolar RPL11
Nat Med
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Mimasu S, Umezawa N, Sato S, Higuchi T, Umehara T, Yokoyama S.
Structurally designed trans-2-phenylcyclopropylamine derivatives potently inhibit histone demethylase LSD1/KDM1 .
Biochemistry
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Naoe H, Araki K, Nagano O, Kobayashi Y, Ishizawa J, Chiyoda T, Shimizu T, Yamamura K, Sasaki Y, Saya H, Kuninaka S.
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Mol. Cell. Biol.
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Shoudai Furuyama, Yoshinari Uehara, Bo Zhang, Yasuhiko Baba, Satomi Abe, Takahiro Iwamoto, Shin-Ichiro Miura, Keijiro Saku
Genotypic Effect of ABCG1 gene promoter -257T>G polymorphism on coronary artery disease severity in Japanese men
J Atheroscler Thromb
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Hiroyuki Oshiumi 1, Yuzuru Suzuki, Misako Matsumoto, Tsukasa Seya
Regulator of complement activation (RCA) gene cluster in Xenopus tropicalis
Immunogenetics
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Satoh T, Arii J, Suenaga T, Wang J, Kogure A, Uehori J, Arase N, Shiratori I, Tanaka S, Kawaguchi Y, Spear PG, Lanier LL, Arase H.
PILRalpha is a herpes simplex virus-1 entry coreceptor that associates with glycoprotein B.
Cell
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Shiori Haga, Norio Yamamoto, Chikako Nakai-Murakami, Yoshiaki Osawa, Kenzo Tokunaga, Tetsutaro Sata, Naoki Yamamoto, Takehiko Sasazuki, Yukihito Ishizaka
Modulation of TNF-alpha-converting Enzyme by the Spike Protein of SARS-CoV and ACE2 Induces TNF-alpha Production and Facilitates Viral Entry
Proc Natl Acad Sci U S A
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105 (22), 7809-14
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Ueno K, Hiura M, Suehiro Y, Hazama S, Hirata H, Oka M, Imai K, Dahiya R, Hinoda Y.
Frizzled-7 as a potential therapeutic target in colorectal cancer
Neoplasia
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Excess magnesium inhibits excess calcium-induced matrix-mineralization and production of matrix gla protein (MGP) by ATDC5 cells.
Biochem Biophys Res Commun
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