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22414
Takeuchi K, Tabe S, Yamamoto Y, Takahashi K, Matsuo M, Ueno Y, Ohtsuka M, Morinaga S, Miyagi Y, Yamaguchi T, Tanimizu N, Taniguchi H.
Protocol for generating a pancreatic cancer organoid associated with heterogeneous tumor microenvironment.
STAR Protoc
2025
6(1):103539
PubMed ID: 39772386
DOI: 10.1016/j.xpro.2024.103539
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22511
Tweedie L, Riccetti MR, Cain B, Qin S, Salomone J, Webb JA, Riesenberg A, Ehrman LA, Waclaw RR, Kovall RA, Gebelein B, Campbell K.
Modelling a pathological GSX2 variant that selectively alters DNA binding reveals hypomorphic mouse basal ganglia and hindbrain defects.
Dis Model Mech
2025
PubMed ID: 39882631
DOI: 10.1242/dmm.052110
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22557
Tasaki K, Satoda Y, Chiba S, Shin HW, Katoh Y, Nakayama K.
Mutually independent and cilia-independent assembly of IFT-A and IFT-B complexes at mother centriole.
Mol Biol Cell
2025
36(4):ar48
PubMed ID: 40020180
DOI: 10.1091/mbc.E24-11-0509
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22611
Mutmainah, Murai Y, Fujimoto A, Kawamura R, Kitamura A, Koolath S, Usuki S, Sasaki M, Orba Y, Igarashi Y, Sawa H, Sato A, Monde K.
Malabaricone C isolated from edible plants as a potential inhibitor of SARS-CoV-2 infection.
Sci Rep
2025
15(1):8518
PubMed ID: 40074774
DOI: 10.1038/s41598-024-83633-8
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22725
Men Y, Hirayama S, Ao S, Sakurai Y, Shibata Y, Lo M, Sato Y, Murata S.
ESCRT-I and PTPN23 mediate microautophagy of ubiquitylated tau aggregates.
J Cell Biol
2025
224(6)
PubMed ID: 40197510
DOI: 10.1083/jcb.202406120
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22752
Mutai H, Kuroda Y, Noji S, Ichikawa S, Matsuo K, Tanaka S, Kataoka N, Fujioka M, Matsunaga T.
Complete omission of exon 21 from Slc12a2 transcripts in mice results in hearing loss.
Sci Rep
2025
15(1):14790
PubMed ID: 40295800
DOI: 10.1038/s41598-025-99827-7
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22756
Fujimoto S, Endo M, Tonomura S, Tsuji F, Haraguchi H, Hasegawa K, Numao T, Izumi A, Tourtas T, Schlötzer-Schrehardt U, Kruse F, Oyama Y, Ikawa M, Jun AS, Koizumi N, Okumura N.
Therapeutic Potential of Emricasan, a Pan-Caspase Inhibitor, in Reducing Cell Death and Extracellular Matrix Accumulation in Fuchs Endothelial Corneal Dystrophy.
Cells
2025
14(7)
PubMed ID: 40214452
DOI: 10.3390/cells14070498
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22918
Sekiya M, Nakanishi-Matsui M, Matsumoto N, Takahashi I, Hanasaka T, Ishiyama-Matsuura E, Araki M, Wakayama T, Nata K.
The a subunit isoforms of V-ATPase are involved in glucose-dependent trafficking of insulin granules.
Sci Rep
2025
15(1):18982
PubMed ID: 40447629
DOI: 10.1038/s41598-025-02997-7
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22931
Urata S, Lee M, Tsuruta T, Igarashi R, Takeda K, Unno H.
Mode of antiviral action of the galactose-specific lectin, AJLec, on the Junin virus propagation.
Antiviral Res
2025
240:106189
PubMed ID: 40381661
DOI: 10.1016/j.antiviral.2025.106189
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22980
Matsugo H, Kitamura T, Takahashi N, Chambers J, Ichikawa A, Katayama M, Li K, Sekine W, Ohira K, Ishida H, Takenaka-Uema A, Uchida K, Shimojima M, Horimoto T, Murakami S.
In vitro and in vivo characterization of a bat merbecovirus with ACE2- and DPP4-independent cell entry.
J Virol
2025
e0072725
PubMed ID: 40525828
DOI: 10.1128/jvi.00727-25
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22983
Hashimoto T, Saito S, Ohata M, Okuwaki M.
The oncoprotein DEK controls growth-regulated gene expression by enhancing the DNA-binding activity of basic leucine zipper transcription factors
FEBS J
2025
2025 May 2
PubMed ID: 40318137
DOI: 10.1111/febs.70124
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22987
Hong Q, Takazakura N, Ozawa H, Ichihara S, Yoshioka K, Obara K, Tanaka Y.
Inhibitory effects of schisandrin A on contractions induced by spasmogenic candidates in porcine coronary arteries.
J Pharmacol Sci
2025
158(4):343-352
PubMed ID: 40543997
DOI: 10.1016/j.jphs.2025.05.016
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22991
Takesue H, Okada S, Doi G, Sugiyama Y, Kusumoto E, Ito T.
Strategic targeting of Cas9 nickase expands tandem gene arrays
Cell Genom
2025
5(4):100811
PubMed ID: 40118067
DOI: 10.1016/j.xgen.2025.100811
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22993
Minowa-Nozawa A, Nozawa T, Murase K, Nakagawa I.
RabGAP1L modulates Rab7A and Rab10 to orchestrate cell-autonomous immunity
Cell Rep
2025
44(5):115599
PubMed ID: 40244851
DOI: 10.1016/j.celrep.2025.115599
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23002
Higuchi S, Liu Y, Shimizu J, Ono C, Itoh Y, Nakai W, Jin H, Kishida K, Takayama K, Okamoto T, Murakami Y, Kinoshita T, Matsuura Y, Shioda T, Arase H.
Evolutionary dynamics of heparan sulfate utilization by SARS-CoV-2.
mBio
2025
e0130325
PubMed ID: 40548749
DOI: 10.1128/mbio.01303-25
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23006
Okamoto K, Mihara Y, Ogasawara S, Murakami T, Ohmori S, Mori T, Umata T, Kawasaki Y, Hirano K, Yano H, Tsuneoka M.
Interaction Between PHF8 and a Segment of KDM2A, Which Is Controlled by the Phosphorylation Status at a Specific Serine in an Intrinsically Disordered Region of KDM2A, Regulates rRNA Transcription and Cell Proliferation in a Breast Cancer Cell Line.
Biomolecules
2025
15(5)
DOI: 10.3390/biom15050661
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23009
Ueno Y, Yamaguchi R, Tanaka Y, Miyake Y, Takaki K, Nakao A, Ozaki R, Yokota Y, Fukai I, Kuwada S, Fukuoka N, Okuda N, Nishida A, Shiba T, Kataoka T.
Expression and localization of lysosomal-associated membrane protein 1- and perforin-based hybrid molecules in the murine cytotoxic T cell line CTLL-2.
Cytotechnology
2025
77(4):129
PubMed ID: 40583867
DOI: 10.1007/s10616-025-00794-8
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19760
etta Takahashi, Nahoko Tomonobu, Rie Kinoshita, Ken-ichi Yamamoto, Hitoshi Murata, Ni Luh Gede Yoni Komalasari, Youyi Chen, Fan Jiang, Yuma Gohara, Toshiki Ochi, I Made Winarsa Ruma, I Wayan Sumardika, Jin Zhou, Tomoko Honjo, Yoshihiko Sakaguchi, Akira Yamauchi, Futoshi Kuribayashi, Eisaku Kondo, Yusuke Inoue, Junichiro Futami, Shinichi Toyooka, Yoshito Zamami, Masakiyo Sakaguchi
Lysyl oxidase-like 4 promotes the invasiveness of triple-negative breast cancer cells by orchestrating the invasive machinery formed by annexin A2 and S100A11 on the cell surface
Frontiers in Oncology
2024
14
DOI: 10.3389/fonc.2024.1371342
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19794
Nakanishi-Matsui M, Matsumoto N, Sun-Wada GH, Wada Y.
Role of the Cytosolic Domain of the a3 Subunit of V-ATPase in the Interaction with Rab7 and Secretory Lysosome Trafficking in Osteoclasts
Biol Pharm Bull
2024
47(1):339-344
PubMed ID: 38296463
DOI: 10.1248/bpb.b23-00833
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19818
Gong L, Voon DC, Nakayama J, Takahashi C, Kohno S.
RB1 loss induces quiescent state through downregulation of RAS signaling in mammary epithelial cells
Cancer Sci
2024
Mar 11
PubMed ID: 38468443
DOI: 10.1111/cas.16122
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21591
Katayama M, Murakami S, Ishida H, Matsugo H, Sekine W, Ohira K, Takenaka-Uema A, Horimoto T.
Antigenic commonality and divergence of hemagglutinin-esterase-fusion protein among influenza D virus lineages revealed using epitope mapping.
J Virol
2024
e0190823
PubMed ID: 38345383
DOI: 10.1128/jvi.01908-23
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21592
Ito F, Yanatori I, Kato K, Toyokuni S.
Protocol for the isolation of GFP-expressing ferroptosis-dependent extracellular vesicles in in vitro cell culture models.
STAR Protoc
2024
5(1):102892
PubMed ID: 38363686
DOI: 10.1016/j.xpro.2024.102892
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21618
Kohyanagi N, Kitamura N, Ikeda S, Shibutani S, Sato K, Ohama T.
PP2A inhibitor SET promotes mTORC1 and Bmi1 signaling through Akt activation and maintains the colony-formation ability of cancer cells.
J Biol Chem
2024
300(1):105584
PubMed ID: 38141761
DOI: 10.1016/j.jbc.2023.105584
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21654
Kobayashi H, Shiba T, Yoshida T, Bolidong D, Kato K, Sato Y, Mochizuki M, Seto T, Kawashiri S, Hanayama R.
Precise analysis of single small extracellular vesicles using flow cytometry.
Sci Rep
2024
14(1):7465
PubMed ID: 38553534
DOI: 10.1038/s41598-024-57974-3
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21667
Kim YJ, Tohyama S, Nagashima T, Nagase M, Hida Y, Hamada S, Watabe AM, Ohtsuka T.
A light-controlled phospholipase C for imaging of lipid dynamics and controlling neural plasticity.
Cell Chem Biol
2024
PubMed ID: 38582083
DOI: 10.1016/j.chembiol.2024.03.001
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21674
Kinoshita S, Ishii M, Ando J, Kimura T, Yamaguchi T, Harada S, Takahashi F, Nakashima K, Nakazawa Y, Yamazaki S, Ohshima K, Takahashi K, Nakauchi H, Ando M.
Rejuvenated iPSC-derived GD2-directed CART Cells Harbor Robust Cytotoxicity Against Small Cell Lung Cancer.
Cancer Res Commun
2024
4(3):723-737
PubMed ID: 38380966
DOI: 10.1158/2767-9764.CRC-23-0259
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21699
Suzuki N, Konuma T, Ikegami T, Akashi S.
Biophysical insights into the dimer formation of human Sirtuin 2.
Protein Sci
2024
33(5):e4994
PubMed ID: 38647411
DOI: 10.1002/pro.4994
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21733
Fujii T, Liang L, Nakayama K, Katoh Y.
Defects in diffusion barrier function of ciliary transition zone caused by ciliopathy variations of TMEM218.
Hum Mol Genet
2024
PubMed ID: 38751342
DOI: 10.1093/hmg/ddae083
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21738
Otsuka Y, Imamura K, Oishi A, Asakawa K, Kondo T, Nakai R, Suga M, Inoue I, Sagara Y, Tsukita K, Teranaka K, Nishimura Y, Watanabe A, Umeyama K, Okushima N, Mitani K, Nagashima H, Kawakami K, Muguruma K, Tsujikawa A, Inoue H.
Phototoxicity avoidance is a potential therapeutic approach for retinal dystrophy caused by EYS dysfunction
JCI Insight
2024
9(8):e174179
PubMed ID: 38646933
DOI: 10.1172/jci.insight.174179
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21753
Tachibana K, Nakamura Y, Do TL, Kihara T, Kawada H, Yamamoto N, Ando K.
Mutations in the SARS-cov-2 spike proteins affected the ACE2-binding affinity during the development of omicron pandemic variants.
Biochem Biophys Res Commun
2024
719:150120
PubMed ID: 38759524
DOI: 10.1016/j.bbrc.2024.150120
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21781
Kitano M, Ohnishi H, Makino A, Miyamoto T, Hayashi Y, Mizuno K, Kaba S, Kawai Y, Kojima T, Kishimoto Y, Yamamoto N, Tomonaga K, Omori K.
An infection model for SARS-CoV-2 using rat transplanted with hiPSC-airway epithelial cells.
Tissue Eng Part A
2024
PubMed ID: 38832872
DOI: 10.1089/ten.TEA.2024.0016
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21812
Yu H, Kohno S, Voon DC, Hussein NH, Zhang Y, Nakayama J, Takegami Y, Takahashi C.
RECK/GPR124-driven WNT signaling in pancreatic and gastric cancer cells.
Cancer Sci
2024
PubMed ID: 38923741
DOI: 10.1111/cas.16258
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21871
Sugiyama Y, Okada S, Daigaku Y, Kusumoto E, Ito T.
Strategic targeting of Cas9 nickase induces large segmental duplications.
Cell Genom
2024
PubMed ID: 39053455
DOI: 10.1016/j.xgen.2024.100610
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21913
Ueno K, Kurazumi H, Suzuki R, Yanagihara M, Mizoguchi T, Harada T, Morikage N, Hamano K.
miR-709 exerts an angiogenic effect through a FGF2 upregulation induced by a GSK3B downregulation
Sci Rep
2024
14(1):11372
PubMed ID: 38762650
DOI: 10.1038/s41598-024-62340-4
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21920
Sekine W, Kamiki H, Ishida H, Matsugo H, Ohira K, Li K, Katayama M, Takenaka-Uema A, Murakami S, Horimoto T.
Adaptation potential of H3N8 canine influenza virus in human respiratory cells.
Sci Rep
2024
14(1):18750
PubMed ID: 39138310
DOI: 10.1038/s41598-024-69509-x
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21932
Miyahara S, Ohuchi M, Nomura M, Hashimoto E, Soga T, Saito R, Hayashi K, Sato T, Saito M, Yamashita Y, Shimada M, Yaegashi N, Yamada H, Tanuma N.
FDX2, an iron-sulfur cluster assembly factor, is essential to prevent cellular senescence, apoptosis or ferroptosis of ovarian cancer cells.
J Biol Chem
2024
107678
PubMed ID: 39151727
DOI: 10.1016/j.jbc.2024.107678
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21934
Tabata K, Kobayashi S, Itakura Y, Gonzalez G, Kabamba CF, Saito S, Sasaki M, Hall WW, Sawa H, Orba Y.
Increased production of orthoflavivirus single-round infectious particles produced in mammalian cells at a suboptimal culture temperature of 28°C.
J Virol Methods
2024
115007
PubMed ID: 39154937
DOI: 10.1016/j.jviromet.2024.115007
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21935
Wang Y, Moh-Moh-Aung A, Wang T, Fujisawa M, Ohara T, Yamamoto KI, Sakaguchi M, Yoshimura T, Matsukawa A.
Exosomal delivery of miR-200b-3p suppresses the growth of hepatocellular carcinoma cells by targeting ERG- and VEGF-mediated angiogenesis.
Gene
2024
148874
PubMed ID: 39159792
DOI: 10.1016/j.gene.2024.148874
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21952
Chiu CT, Tsai HH, Chen JY, Hu CJ, Chen HW.
An Immunoreceptor-Targeting Strategy with Minimalistic C3b Peptide Fusion Enhances SARS-CoV-2 RBD mRNA Vaccine Immunogenicity.
Int J Nanomedicine
2024
19:7201-7214
PubMed ID: 39050877
DOI: 10.2147/IJN.S463546
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21956
Ueno M, Sugiyama H, Li F, Nishimura T, Arakawa H, Chen X, Cheng X, Takeuchi S, Takeshita Y, Takamura T, Miyagi S, Toyama T, Soga T, Masuo Y, Kato Y, Nakamura H, Tsujiguchi H, Hara A, Tajima A, Noguchi-Shinohara M, Ono K, Kurayoshi K, Kobayashi M, Tadokoro Y, Kasahara A, Shoulkamy MI, Maeda K, Ogoshi T, Hirao A.
A Supramolecular Biosensor for Rapid and High-Throughput Quantification of a Disease-Associated Niacin Metabolite.
Anal Chem
2024
PubMed ID: 39183562
DOI: 10.1021/acs.analchem.4c02653
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21967
Okada M, Yamasaki S, Nakazato H, Hirahara Y, Ishibashi T, Kawamura M, Shimizu K, Fujii SI.
ARID1A-Deficient Tumors Acquire Immunogenic Neoantigens during the Development of Resistance to Targeted Therapy.
Cancer Res
2024
84(17):2792-2805
PubMed ID: 39228255
DOI: 10.1158/0008-5472.CAN-23-2846
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21975
Koike T, Sato T, Oe S, Hayashi S, Seki-Omura R, Nakano Y, Iwashita H, Sato Y, Hirahara Y, Kitada M.
CD34 distribution in C-fiber low threshold mechanoreceptors in the mouse dorsal root ganglion and spinal cord.
Brain Res
2024
1846:149227
PubMed ID: 39255903
DOI: 10.1016/j.brainres.2024.149227
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21979
Mori S, Kohyama M, Yasumizu Y, Tada A, Tanzawa K, Shishido T, Kishida K, Jin H, Nishide M, Kawada S, Motooka D, Okuzaki D, Naito R, Nakai W, Kanda T, Murata T, Terao C, Ohmura K, Arase N, Kurosaki T, Fujimoto M, Suenaga T, Kumanogoh A, Sakaguchi S, Ogawa Y, Arase H.
Neoself-antigens are the primary target for autoreactive T cells in human lupus.
Cell
2024
PubMed ID: 39276775
DOI: 10.1016/j.cell.2024.08.025
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21993
Kashiwagi M, Beck G, Kanuka M, Arai Y, Tanaka K, Tatsuzawa C, Koga Y, Saito YC, Takagi M, Oishi Y, Sakaguchi M, Baba K, Ikuno M, Yamakado H, Takahashi R, Yanagisawa M, Murayama S, Sakurai T, Sakai K, Nakagawa Y, Watanabe M, Mochizuki H, Hayashi Y.
A pontine-medullary loop crucial for REM sleep and its deficit in Parkinson's disease.
Cell
2024
PubMed ID: 39303715
DOI: 10.1016/j.cell.2024.08.046
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22065
Nagai N, Shioiri T, Hatano S, Sugiura N, Watanabe H.
Regulatory role of Heparan sulfate in leptin signaling.
Cell Signal
2024
124:111456
PubMed ID: 39384005
DOI: 10.1016/j.cellsig.2024.111456
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22066
Saji T, Endo M, Okada Y, Minami Y, Nishita M.
KIF1C facilitates retrograde transport of lysosomes through Hook3 and dynein.
Commun Biol
2024
7(1):1305
PubMed ID: 39394274
DOI: 10.1038/s42003-024-07023-6
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22154
Matsuzaki Y, Fukai Y, Konno A, Hirai H.
Optimal different adeno-associated virus capsid/promoter combinations to target specific cell types in the common marmoset cerebral cortex.
Mol Ther Methods Clin Dev
2024
32(4):101337
PubMed ID: 39391837
DOI: 10.1016/j.omtm.2024.101337
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22165
Kanadome T, Hoshino N, Nagai T, Yagi T, Matsuda T.
Protocol to visualize trans-interaction of clustered protocadherin using cIPAD, a fluorescent indicator, in cultured human cells and mouse neurons.
STAR Protoc
2024
5(1):102844
PubMed ID: 38277267
DOI: 10.1016/j.xpro.2024.102844
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22176
Onishi A, Tsunekawa Y, Mandai M, Ishimaru A, Ohigashi Y, Sho J, Yasuda K, Suzuki K, Izpisua Belmonte JC, Matsuzaki F, Takahashi M.
Optimization of HITI-Mediated Gene Insertion for Rhodopsin and Peripherin-2 in Mouse Rod Photoreceptors: Targeting Dominant Retinitis Pigmentosa.
Invest Ophthalmol Vis Sci
2024
65(13):38
PubMed ID: 39556087
DOI: 10.1167/iovs.65.13.38
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22179
Sakaguchi M, Kinoshita R, Tomonobu N, Sakaguchi Y, Futami J, Yamauchi A, Murata H, Yamamoto KI, Takahashi T, Gohara Y, Ochi T, Jiang F, Komalasari NLGY, Chen Y, Ruma IMW, Sumardika IW, Zhou J, Honjo T, Kuribayashi F, Sagayama K, Toyooka S, Kondo E, Inoue Y.
Enhanced design of pCMViR-TSC plasmid vector for sustainably high cargo gene expression in mammalian cells.
In Vitro Cell Dev Biol Anim
2024
PubMed ID: 39570532
DOI: 10.1007/s11626-024-00992-2
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22201
Yamashita M, Ogawa C, Zhang B, Kobayashi T, Nomura A, Barker C, Zou C, Yamanaka S, Hayashi KI, Shinkai Y, Moro K, Fargarasan S, Imami K, Seita J, Shirai F, Sawasaki T, Kanemaki MT, Taniuchi I.
Cell-type specific, inducible and acute degradation of targeted protein in mice by two degron systems.
Nat Commun
2024
15(1):10129
PubMed ID: 39613744
DOI: 10.1038/s41467-024-54308-9
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22234
Chida-Nagai A, Akagawa H, Sawai S, Ma YJ, Yakuwa S, Muneuchi J, Yasuda K, Yamazawa H, Yamamoto T, Takakuwa E, Tomaru U, Furutani Y, Kato T, Harada G, Inai K, Nakanishi T, Manabe A, Takeda A, Jing ZC.
Identification of Prostaglandin I2 Synthase Rare Variants in Patients With Williams Syndrome and Severe Peripheral Pulmonary Stenosis
J Am Heart Assoc
2024
13(9):e032872
PubMed ID: 38639351
DOI: 10.1161/JAHA.123.032872
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22235
Shinoda S, Sakai Y, Matsui T, Uematsu M, Koyama-Honda I, Sakamaki JI, Yamamoto H, Mizushima N.
Syntaxin 17 recruitment to mature autophagosomes is temporally regulated by PI4P accumulation
Elife
2024
12:RP92189
PubMed ID: 38831696
DOI: 10.7554/eLife.92189
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22236
Lin N, Miyamoto K, Ogawara T, Sakurai S, Kizaka-Kondoh S, Kadonosono T.
Epitope binning for multiple antibodies simultaneously using mammalian cell display and DNA sequencing
Commun Biol
2024
7(1):652
PubMed ID: 38806676
DOI: 10.1038/s42003-024-06363-7
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22237
Mubuchi A, Takechi M, Nishio S, Matsuda T, Itoh Y, Sato C, Kitajima K, Kitagawa H, Miyata S.
Assembly of neuron- and radial glial-cell-derived extracellular matrix molecules promotes radial migration of developing cortical neurons
Elife
2024
12:RP92342
PubMed ID: 38512724
DOI: 10.7554/eLife.92342
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22238
Takeshita M, Suzuki K, Nakazawa M, Kamata H, Ishii M, Oyamada Y, Oshima H, Usuda S, Tsunoda K, Takeuchi T.
Disease-specific autoantibody production in the lungs and salivary glands of anti-synthetase syndrome
Front Immunol
2024
15:1265792
PubMed ID: 38938569
DOI: 10.3389/fimmu.2024.1265792
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22241
Tanaka R, Sugiura K, Osabe K, Hattori M, Nagai T.
Genetically encoded bioluminescent glucose indicator for biological research.
Biochem Biophys Res Commun
2024
742:151092
PubMed ID: 39626367
DOI: 10.1016/j.bbrc.2024.151092
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22251
Hirabayashi Y, Lewis TL Jr, Du Y, Virga DM, Decker AM, Coceano G, Alvelid J, Paul MA, Hamilton S, Kneis P, Takahashi Y, Gaublomme JT, Testa I, Polleux F.
Most axonal mitochondria in cortical pyramidal neurons lack mitochondrial DNA and consume ATP
bioRxiv
2024
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PubMed ID: 38405915
DOI: 10.1101/2024.02.12.579972
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22285
Varner LR, Chaya T, Maeda Y, Tsutsumi R, Zhou S, Tsujii T, Okuzaki D, Furukawa T.
The deubiquitinase Otud7b suppresses cone photoreceptor degeneration in mouse models of retinal degenerative diseases
iScience
2024
27(4):109380
PubMed ID: 38510130
DOI: 10.1016/j.isci.2024.109380
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22311
Takada S, Gallo S, Silva S, Tanaka H, Pincheira O, Zúñiga J, Villarroel M, Hidalgo X, Melo-Tanner J, Suzuki H, Machida S, Takahashi H, Miyake N.
A Novel AGR2 Variant Causing Aberrant Monomer-Dimer Equilibrium Leading to Severe Respiratory and Digestive Symptoms
J Clin Immunol
2024
45(1):55
PubMed ID: 39673647
DOI: 10.1007/s10875-024-01847-x
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22320
Jiang F, Chen Y, Tomonobu N, Kinoshita R, Komalasari NLGY, Kasano-Camones CI, Ninomiya K, Murata H, Yamamoto KI, Gohara Y, Ochi T, Ruma IMW, Sumardika IW, Zhou J, Honjo T, Sakaguchi Y, Yamauchi A, Kuribayashi F, Futami J, Kondo E, Inoue Y, Toyooka S, Sakaguchi M.
Dissection of the signal transduction machinery responsible for the lysyl oxidase-like 4-mediated increase in invasive motility in triple-negative breast cancer cells: mechanistic insight into the integrin-β1-NF-κB-MMP9 axis
Front Oncol
2024
14:1371307.
PubMed ID: 38863623
DOI: 10.3389/fonc.2024.1371307
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22347
Mori K, Suzuki T, Waki U, Hayashi S, Kadono S, Kawahara R, Takeuchi M, Mizuta H, Dohmae N, Katayama R, Simizu S.
Identification of C-mannosylation in a receptor tyrosine kinase AXL
Glycobiology
2024
34(11):cwae096
PubMed ID: 39660536
DOI: 10.1093/glycob/cwae096
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22348
Yamazaki S, Fujii T, Chiba S, Shin HW, Nakayama K, Katoh Y.
TXNDC15, an ER-localized thioredoxin-like transmembrane protein, contributes to ciliary transition zone integrity.
J Cell Sci
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Mol Cell Proteomics
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PLoS Biol
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The Use of Carboxyfluorescein Reveals the Transport Function of MCT6/SLC16A5 Associated with CD147 as a Chloride-Sensitive Organic Anion Transporter in Mammalian Cells
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Development of a novel plate reader-based antibody-dependent enhancement (ADE) assay for orthoflavivirus infections.
J Virol Methods
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Stimulation of interferon-β responses by aberrant SARS-CoV-2 small viral RNAs acting as retinoic acid-inducible gene-I agonists
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Protein quality control machinery supports primary ciliogenesis by eliminating GDP-bound Rab8- family GTPases
iScience
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Cofilin promotes vasculogenic mimicry by regulating the actin cytoskeleton in human breast cancer cells
FEBS Lett
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Novel extracellular role of REIC/Dkk-3 protein in PD-L1 regulation in cancer cells
J Mol Med (Berl)
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Lysyl oxidase-like 4 exerts an atypical role in breast cancer progression that is dependent on the enzymatic activity that targets the cell-surface annexin A2
Front Oncol
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Visualization of trans homophilic interaction of clustered protocadherin in neurons
Proc Natl Acad Sci U S A
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GAS41 promotes H2A.Z deposition through recognition of the N terminus of histone H3 by the YEATS domain
Proc Natl Acad Sci U S A
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iPSC-derived hypoimmunogenic tissue resident memory T cells mediate robust anti-tumor activity against cervical cancer
Cell Rep Med
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2-thiouridine is a broad-spectrum antiviral nucleoside analogue against positive-strand RNA viruses
Proc Natl Acad Sci U S A
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The transcription factor NRF1 (NFE2L1) activates aggrephagy by inducing p62 and GABARAPL1 after proteasome inhibition to maintain proteostasis
Sci Rep
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l-Type amino acid transporter 1 in hypothalamic neurons in mice maintains energy and bone homeostasis
JCI Insight
2023
8(7):e154925
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MEK5-ERK5 Axis Promotes Self-renewal and Tumorigenicity of Glioma Stem Cells
Cancer Res Commun
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Rheumatoid factor recognizes specific domains of the IgG heavy chain complexed with HLA class II molecules
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Disruption of the Mammalian Ccr4-Not Complex Contributes to Transcription-Mediated Genome Instability
Cells
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12(14):1868
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Wuputra K, Tsai MH, Kato K, Ku CC, Pan JB, Yang YH, Saito S, Wu CC, Lin YC, Cheng KH, Kuo KK, Noguchi M, Nakamura Y, Yoshioka T, Wu DC, Lin CS, Yokoyama KK.
Jdp2 is a spatiotemporal transcriptional activator of the AhR via the Nrf2 gene battery
Inflamm Regen
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Hirabayashi D, Yamamoto KI, Maruyama A, Tomonobu N, Kinoshita R, Chen Y, Komalasari NLGY, Murata H, Gohara Y, Jiang F, Zhou J, Ruma IMW, Sumardika IW, Yamauchi A, Kuribayashi F, Toyooka S, Inoue Y, Sakaguchi M.
LOXL1 and LOXL4 are novel target genes of the Zn2+-bound form of ZEB1 and play a crucial role in the acceleration of invasive events in triple-negative breast cancer cells
Front Oncol
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NEAT1_2 and DAZAP1, Paraspeckle Components, Interact with PXR to Negatively Regulate CYP3A4 Induction
Drug Metab Dispos
2023
51(10):1230-1237
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Sasaki M, Tabata K, Kishimoto M, Itakura Y, Kobayashi H, Ariizumi T, Uemura K, Toba S, Kusakabe S, Maruyama Y, Iida S, Nakajima N, Suzuki T, Yoshida S, Nobori H, Sanaki T, Kato T, Shishido T, Hall WW, Orba Y, Sato A, Sawa H.
S-217622, a SARS-CoV-2 main protease inhibitor, decreases viral load and ameliorates COVID-19 severity in hamsters.
Sci Transl Med
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15(679):eabq4064
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Okamoto K, Kamikubo Y, Yamauchi K, Okamoto S, Takahashi M, Ishida Y, Koike M, Ikegaya Y, Sakurai T, Hioki H.
Specific AAV2/PHP.eB-mediated gene transduction of CA2 pyramidal cells via injection into the lateral ventricle.
Sci Rep
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Hiyamizu S, Qiu H, Vuolo L, Stevenson NL, Shak C, Heesom KJ, Hamada Y, Tsurumi Y, Chiba S, Katoh Y, Stephens DJ, Nakayama K.
Multiple interactions of the dynein-2 complex with the IFT-B complex are required for effective IFT.
J Cell Sci
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PubMed ID: 36632779
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Shoji H, Kitao K, Miyazawa T, Nakagawa S.
Potentially reduced fusogenicity of syncytin-2 in New World monkeys.
FEBS Open Bio
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PubMed ID: 36647789
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Morihiro K, Osumi H, Morita S, Hattori T, Baba M, Harada N, Ohashi R, Okamoto A.
Oncolytic Hairpin DNA Pair: Selective Cytotoxic Inducer through MicroRNA-Triggered DNA Self-Assembly.
J Am Chem Soc
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Sato M, Maishi N, Hida Y, Yanagawa-Matsuda A, Alam MT, Sakakibara-Konishi J, Nam JM, Onodera Y, Konno S, Hida K.
Angiogenic inhibitor pre-administration improves the therapeutic effects of immunotherapy.
Cancer Med
2023
PubMed ID: 36808261
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Yoshimoto S, Suzuki T, Otani N, Takahashi D, Toshima K, Dohmae N, Simizu S.
Destabilization of vitelline membrane outer layer protein 1 homolog (VMO1) by C-mannosylation.
FEBS Open Bio
2023
PubMed ID: 36680395
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Ota A, Morita H, Naganuma T, Miyamoto M, Jojima K, Nojiri K, Matsuda J, Kihara A.
Bifunctional DEGS2 has higher hydroxylase activity toward substrates with very-long-chain fatty acids in the production of phytosphingosine-ceramides.
J Biol Chem
2023
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Tanikawa S, Ebisu Y, Sedlačík T, Semba S, Nonoyama T, Kurokawa T, Hirota A, Takahashi T, Yamaguchi K, Imajo M, Kato H, Nishimura T, Tanei ZI, Tsuda M, Nemoto T, Gong JP, Tanaka S.
Engineering of an electrically charged hydrogel implanted into a traumatic brain injury model for stepwise neuronal tissue reconstruction
Sci Rep
2023
13(1):2233
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21104
Kawano T, Kashiwagi M, Kanuka M, Chen CK, Yasugaki S, Hatori S, Miyazaki S, Tanaka K, Fujita H, Nakajima T, Yanagisawa M, Nakagawa Y, Hayashi Y.
ER proteostasis regulators cell-non-autonomously control sleep.
Cell Rep
2023
42(3):112267
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Tao F, Kitamura K, Hanada S, Sugimoto K, Furihata T, Kojima N.
Rapid and Stable Formation Method of Human Astrocyte Spheroid in a High Viscous Methylcellulose Medium and Its Functional Advantages.
Bioengineering (Basel)
2023
10(3)
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21159
Watanabe T, Narahari A, Bhardwaj E, Kuriyama K, Nishimura M, Izumi T, Fujimuro M, Ohno S.
Conserved cysteine residues in Kaposi's sarcoma herpesvirus ORF34 are necessary for viral production and viral pre-initiation complex formation.
bioRxiv
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PubMed ID: 36945456
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Noritsugu K, Suzuki T, Dodo K, Ohgane K, Ichikawa Y, Koike K, Morita S, Umehara T, Ogawa K, Sodeoka M, Dohmae N, Yoshida M, Ito A.
Lysine long-chain fatty acylation regulates the TEAD transcription factor.
Cell Rep
2023
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Jojima K, Kihara A.
Metabolism of sphingadiene and characterization of the sphingadiene-producing enzyme FADS3.
Biochim Biophys Acta Mol Cell Biol Lipids
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1868(8):159335
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21222
Takahashi T, Shirai J, Matsuda M, Nakanaga S, Matsushita S, Wakita K, Hayashishita M, Suzuki R, Noguchi A, Yokota N, Kawahara H.
Protein quality control machinery supports primary ciliogenesis by eliminating GDP-bound Rab8-family GTPases.
iScience
2023
26(5):106652
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Kasuga Y, Ouda R, Watanabe M, Sun X, Kimura M, Hatakeyama S, Kobayashi KS.
FBXO11 constitutes a major negative regulator of MHC class II through ubiquitin-dependent proteasomal degradation of CIITA.
Proc Natl Acad Sci U S A
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120(24):e2218955120
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Nishi K, Yoshii A, Abell L, Zhou B, Frausto R, Ritterhoff J, McMillen TS, Sweet I, Wang Y, Gao C, Tian R.
Branched-chain keto acids inhibit mitochondrial pyruvate carrier and suppress gluconeogenesis in hepatocytes.
Cell Rep
2023
42(6):112641
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Hiyamizu S, Qiu H, Tsurumi Y, Hamada Y, Katoh Y, Nakayama K.
Dynein-2-driven intraciliary retrograde trafficking indirectly requires multiple interactions of IFT54 in the IFT-B complex with the dynein-2 complex.
Biol Open
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PubMed ID: 37309605
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Shimohata A, Rai D, Akagi T, Usui S, Ogiwara I, Kaneda M.
The intracellular C-terminal domain of mGluR6 contains ER retention motifs.
Mol Cell Neurosci
2023
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Yamaguchi S, Kamino M, Hamamura M, Otsuguro KI.
The cytosolic N-terminal region of heterologously-expressed transmembrane channel-like protein 1 (TMC1) can be cleaved in HEK293 cells.
PLoS One
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Okada M, Shimizu K, Nakazato H, Yamasaki S, Fujii SI.
Detection of mutant antigen-specific T cell receptors against multiple myeloma for T cell engineering.
Mol Ther Methods Clin Dev
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Morishita K, Kondo J, Sakon D, Hayashibara A, Tamura I, Shimizu K, Takamatsu S, Murata K, Kamada Y, Miyoshi E.
Prohaptoglobin is a possible prognostic biomarker for colorectal cancer.
Biochem Biophys Res Commun
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Tanaka Y, Morozumi A, Hirokawa N.
Nodal flow transfers polycystin to determine mouse left-right asymmetry.
Dev Cell
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PubMed ID: 37413993
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Isolation and evaluation of erythroid progenitors in the livers of larval, froglet, and adult Xenopus tropicalis.
Biol Open
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PubMed ID: 37421150
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Matsuura-Suzuki E, Toh H, Iwasaki S.
Human-rabbit Hybrid Translation System to Explore the Function of Modified Ribosomes.
Bio Protoc
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Tokuma H, Sakano D, Tanabe K, Tanizawa Y, Shiraki N, Kume S.
Selective proteasome degradation of C-terminally-truncated human WFS1 in pancreatic beta cells.
FEBS Open Bio
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PubMed ID: 37440664
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Takahashi G, Miyaoka Y.
Large-scale single-cell cloning of genome-edited cultured human cells by On-chip SPiS.
STAR Protoc
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4(3):102364
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Goto M, Nishimura G, Sato H, Yamaguchi Y, Morimoto N, Hashimoto H, Takahashi N.
Pharmacological profile of upacicalcet, a novel positive allosteric modulator of calcium-sensing receptor, in vitro and in vivo.
Eur J Pharmacol
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Komuro H, Shinohara S, Fukushima Y, Demachi-Okamura A, Muraoka D, Masago K, Matsui T, Sugita Y, Takahashi Y, Nishida R, Takashima C, Ohki T, Shigematsu Y, Watanabe F, Adachi K, Fukuyama T, Hamana H, Kishi H, Miura D, Tanaka Y, Onoue K, Onoguchi K, Yamashita Y, Stratford R, Clancy T, Yamaguchi R, Kuroda H, Doi K, Iwata H, Matsushita H.
Single-cell sequencing on CD8+ TILs revealed the nature of exhausted T cells recognizing neoantigen and cancer/testis antigen in non-small cell lung cancer.
J Immunother Cancer
2023
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PubMed ID: 37544663
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Kanadome T, Hoshino N, Nagai T, Yagi T, Matsuda T.
Visualization of trans-interactions of a protocadherin-α between processes originating from single neurons.
iScience
2023
26(7):107238
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Tsuji K, Kikuchi E, Takashima Y, Shoji T, Takahashi H, Ito S, Morinaga D, Kashima M, Maeda M, Kitai H, Kikuchi J, Sakakibara-Konishi J, Konno S.
Inhibition of non-homologous end joining mitigates paclitaxel resistance resulting from mitotic slippage in non-small cell lung cancer
Cell Cycle
2023
22(17):1854-1864
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Suzuki MM, Iijima K, Ogami K, Shinjo K, Murofushi Y, Xie J, Wang X, Kitano Y, Mamiya A, Kibe Y, Nishimura T, Ohka F, Saito R, Sato S, Kobayashi J, Yao R, Miyata K, Kataoka K, Suzuki HI, Kondo Y.
TUG1-mediated R-loop resolution at microsatellite loci as a prerequisite for cancer cell proliferation.
Nat Commun
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Xu J, Hashino T, Tanaka R, Kawaguchi K, Yoshida H, Kataoka T.
The BCL-2 family protein BCL-RAMBO interacts and cooperates with GRP75 to promote its apoptosis signaling pathway.
Sci Rep
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Kanao E, Ishida K, Mizuta R, Li Y, Imami K, Tanigawa T, Sasaki Y, Akiyoshi K, Adachi J, Otsuka K, Ishihama Y, Kubo T.
Rapid and Highly Efficient Purification of Extracellular Vesicles Enabled by a TiO2 Hybridized Spongy-like Polymer.
Anal Chem
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PubMed ID: 37703188
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Sogawa A, Komori R, Yanagitani K, Ohfurudono M, Tsuru A, Kadoi K, Kimata Y, Yoshida H, Kohno K.
Signal sequence-triage is activated by translocon obstruction sensed by an ER stress sensor IRE1α.
Cell Struct Funct
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PubMed ID: 37766570
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Takeuchi K, Tabe S, Takahashi K, Aoshima K, Matsuo M, Ueno Y, Furukawa Y, Yamaguchi K, Ohtsuka M, Morinaga S, Miyagi Y, Yamaguchi T, Tanimizu N, Taniguchi H.
Incorporation of human iPSC-derived stromal cells creates a pancreatic cancer organoid with heterogeneous cancer-associated fibroblasts.
Cell Rep
2023
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Anal Chem
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Niacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma.
Nat Commun
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Front Cell Dev Biol
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HOXA10 promotes Gdf5 expression in articular chondrocytes
Sci Rep
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Determining the structure of protein-bound ceramides, essential lipids for skin barrier function
iScience
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26(11):108248
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An interactive deep learning-based approach reveals mitochondrial cristae topologies
PLoS Biol
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Mol Biol Evol
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Cell Rep
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Cold atmospheric nitrogen plasma induces metal-initiated cell death by cell membrane rupture and mitochondrial perturbation
Cell Biochem Funct
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Local anesthetic lidocaine induces growth suppression of HeLa cells by decreasing and changing the cellular localization of the proliferation marker Ki-67
Genes Cells
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Miku Akishino, Yuko Aoki, Hajime Baba, Makio Asakawa, Yoichiro Hama, Susumu Mitsutake
Red algae-derived isofloridoside activates the sweet taste receptor T1R2/T1R3
Food Bioscience
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Brain Commun
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4(6):fcac304
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Influenza A Virus Agnostic Receptor Tropism Revealed Using a Novel Biological System with Terminal Sialic Acid Knockout Cells
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Dihydromaniwamycin E, a Heat-Shock Metabolite from Thermotolerant Streptomyces sp. JA74, Exhibiting Antiviral Activity against Influenza and SARS-CoV-2 Viruses
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Pathological Studies on Hantaan Virus-Infected Mice Simulating Severe Hemorrhagic Fever with Renal Syndrome
Viruses
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Fluorochromized tyramide-glucose oxidase as a multiplex fluorescent tyramide signal amplification system for histochemical analysis
Sci Rep
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Mblk-1/E93, an ecdysone related-transcription factor, targets synaptic plasticity-related genes in the honey bee mushroom bodies
Sci Rep
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NCOA4 drives ferritin phase separation to facilitate macroferritinophagy and microferritinophagy
J Cell Biol
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First direct evidence for direct cell-membrane penetrations of polycationic homopoly(amino acid)s produced by bacteria
Commun Biol
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Regulation of CCR4-NOT complex deadenylase activity and cellular responses by MK2-dependent phosphorylation of CNOT2
RNA Biol
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A distinct mammalian disome collision interface harbors K63-linked polyubiquitination of uS10 to trigger hRQT-mediated subunit dissociation
Nat Commun
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Tsuji H, Ohmura K, Jin H, Naito R, Arase N, Kohyama M, Suenaga T, Sakakibara S, Kochi Y, Okada Y, Yamamoto K, Kikutani H, Morinobu A, Mimori T, Arase H.
Anti-dsDNA antibodies recognize DNA presented on HLA class II molecules of systemic lupus erythematosus risk alleles.
Arthritis Rheumatol
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PubMed ID: 34164946
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Tanaka K, Kandori S, Sakka S, Nitta S, Tanuma K, Shiga M, Nagumo Y, Negoro H, Kojima T, Mathis BJ, Shimazui T, Watanabe M, Sato TA, Miyamoto T, Matsuzaka T, Shimano H, Nishiyama H.
ELOVL2 promotes cancer progression by inhibiting cell apoptosis in renal cell carcinoma.
Oncol Rep
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Cell surface-expressed Ro52/IgG/HLA-DR complex is targeted by autoantibodies in patients with inflammatory myopathies.
J Autoimmun
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Combinations of deletion and missense variations of the dynein-2 DYNC2LI1 subunit found in skeletal ciliopathies cause ciliary defects.
Sci Rep
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Hiraiwa M, Fukasawa K, Iezaki T, Sabit H, Horie T, Tokumura K, Iwahashi S, Murata M, Kobayashi M, Suzuki A, Park G, Kaneda K, Todo T, Hirao A, Nakada M, Hinoi E.
SMURF2 phosphorylation at Thr249 modifies glioma stemness and tumorigenicity by regulating TGF-β receptor stability.
Commun Biol
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Nomura T, Nagao K, Shirai R, Gotoh H, Umeda M, Ono K.
Temperature sensitivity of Notch signaling underlies species-specific developmental plasticity and robustness in amniote brains.
Nat Commun
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Dimethyl sulfoxide stimulates the AhR-Jdp2 axis to control ROS accumulation in mouse embryonic fibroblasts
Cell Biol Toxicol
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Jin H, Kishida K, Arase N, Matsuoka S, Nakai W, Kohyama M, Suenaga T, Yamamoto K, Sasazuki T, Arase H.
Abrogation of self-tolerance by misfolded self-antigens complexed with MHC class II molecules.
Sci Adv
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Spectroscopic second and third harmonic generation microscopy using a femtosecond laser source in the third near-infrared (NIR-III) optical window.
Biomed Opt Express
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Miyajima Y, Noguchi S, Tanaka Y, Li JR, Nishimura H, Kishima M, Lim J, Furuhata E, Suzuki T, Kasukawa T, Suzuki H.
Prediction of transcription factors associated with DNA demethylation during human cellular development.
Chromosome Res
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Chino H, Yamasaki A, Ode KL, Ueda HR, Noda NN, Mizushima N.
Phosphorylation by casein kinase 2 enhances the interaction between ER-phagy receptor TEX264 and ATG8 proteins.
EMBO Rep
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Nashimoto Y, Matsushita F, Dijkstra JM, Nakamura Y, Akiyama H, Hamako J, Morita T, Araki S, Matsui T.
Bitiscetin-3, a Novel C-Type Lectin-like Protein Cloned from the Venom Gland of the Viper Bitis arietans, Induces Platelet Agglutination and Inhibits Binding of Von Willebrand Factor to Collagen.
Toxins (Basel)
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Tyrosinase suppresses vasculogenic mimicry in human melanoma cells.
Oncol Lett
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Satoda Y, Noguchi T, Fujii T, Taniguchi A, Katoh Y, Nakayama K.
BROMI/TBC1D32 together with CCRK/CDK20 and FAM149B1/JBTS36 contributes to IFT turnaround involving ICK/CILK1.
Mol Biol Cell
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DUSP4 Inactivation Leads to Reduced Extracellular Signal‒Regulated Kinase Activity through Upregulation of DUSP6 in Melanoma Cells
J Invest Dermatol
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Yasui R, Matsui A, Sekine K, Okamoto S, Taniguchi H.
Highly Sensitive Detection of Human Pluripotent Stem Cells by Loop-Mediated Isothermal Amplification.
Stem Cell Rev Rep
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20729
Ishida Y, Tasaki K, Katoh Y, Nakayama K.
Molecular basis underlying the ciliary defects caused by IFT52 variations found in skeletal ciliopathies.
Mol Biol Cell
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Hada M, Miura H, Tanigawa A, Matoba S, Inoue K, Ogonuki N, Hirose M, Watanabe N, Nakato R, Fujiki K, Hasegawa A, Sakashita A, Okae H, Miura K, Shikata D, Arima T, Shirahige K, Hiratani I, Ogura A.
Highly rigid H3.1/H3.2-H3K9me3 domains set a barrier for cell fate reprogramming in trophoblast stem cells
Genes Dev
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Sasaki K, Suzuki M, Sonoda T, Schneider-Poetsch T, Ito A, Takagi M, Fujishiro S, Sohtome Y, Dodo K, Umehara T, Aburatani H, Shin-Ya K, Nakao Y, Sodeoka M, Yoshida M.
Visualization of the dynamic interaction between nucleosomal histone H3K9 tri-methylation and HP1α chromodomain in living cells
Cell Chem Biol
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Matsuura-Suzuki E, Shimazu T, Takahashi M, Kotoshiba K, Suzuki T, Kashiwagi K, Sohtome Y, Akakabe M, Sodeoka M, Dohmae N, Ito T, Shinkai Y, Iwasaki S.
METTL18-mediated histidine methylation of RPL3 modulates translation elongation for proteostasis maintenance
Elife
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Yamada T, Fukasawa K, Horie T, Kadota T, Lyu J, Tokumura K, Ochiai S, Iwahashi S, Suzuki A, Park G, Ueda R, Yamamoto M, Kitao T, Shirahase H, Ochi H, Sato S, Iezaki T, Hinoi E.
The role of CDK8 in mesenchymal stem cells in controlling osteoclastogenesis and bone homeostasis.
Stem Cell Reports
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PubMed ID: 35777359
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Zhu Z, Kitano T, Morimatsu M, Tanaka A, Morioka R, Lin X, Orino K, Yoshikawa Y.
BRCA2 C-Terminal RAD51-Binding Domain Confers Resistance to DNA-Damaging Agents
Int J Mol Sci
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16747
Fujii K, Morita S, Mochizuki M, Shibuya-Takahashi R, Fujimori H, Yamaguchi K, Abe J, Yamazaki T, Imai T, Sugamura K, Yasuda J, Satoh K, Sato I, Saito-Koyama R, Fujishima F, Sasano H, Kato Y, Matsuura K, Asada Y, Tamai K.
Establishment of a monoclonal antibody against glycosylated CD271 specific for cancer cells in immunohistochemistry
Cancer Sci . 2022 Mar 28
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Song W, Isaji T, Nakano M, Liang C, Fukuda T, Gu J.
O-GlcNAcylation regulates β1,4-GlcNAc-branched N-glycan biosynthesis via the OGT/SLC35A3/GnT-IV axis
FASEB J
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36(2):e22149
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Kitanishi T, Tashiro M, Kitanishi N, Mizuseki K.
Intersectional, anterograde transsynaptic targeting of neurons receiving monosynaptic inputs from two upstream regions
Commun Biol
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Otsuka K, Sawai-Ogawa M, Kihara A.
Formation of fatty alcohols-components of meibum lipids-by the fatty acyl-CoA reductase FAR2 is essential for dry eye prevention
FASEB J
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36(4):e22216
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Takahashi S, Shibutani S, Iwata H.
Nuclear-targeted 4E-BP1 is dephosphorylated, induces nuclear translocation of eIF4E, and alters mRNA translation
Exp Cell Res
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418(1):113246
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20788
Oishi T, Ito M, Koizumi S, Horikawa M, Yamamoto T, Yamagishi S, Yamasaki T, Sameshima T, Suzuki T, Sugimura H, Namba H, Kurozumi K.
Efficacy of HSV-TK/GCV system suicide gene therapy using SHED expressing modified HSV-TK against lung cancer brain metastases.
Mol Ther Methods Clin Dev
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26:253-265
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20822
Deai M, Oya R, Saso N, Tanaka A, Uchida I, Miyake Y, Tachihara R, Otsugu M, Mine A, Sato K, Tomura H.
Ethylenediaminetetraacetic acid (EDTA) enhances cAMP production in human TDAG8-expressing cells.
Biochem Biophys Res Commun
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626:15-20
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Izumi A, Yamamoto K, Kawaguchi M, Yamashita F, Fukushima T, Kiwaki T, Tanaka H, Yamashita Y, Kataoka H.
Insufficiency of hepatocyte growth factor activator inhibitor-1 confers lymphatic invasion of tongue carcinoma cells
Cancer Sci
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113(6):2179-2193
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Kashio M, Masubuchi S, Tominaga M.
Protein kinase C (PKC)-mediated phosphorylation of TRPM2 Thr738 counteracts the effect of cytosolic Ca2+ and elevates the temperature threshold.
J Physiol
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PubMed ID: 36042566
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Zhou Z, Katoh Y, Nakayama K.
CEP19-RABL2-IFT-B axis controls BBSome-mediated ciliary GPCR export.
Mol Biol Cell
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PubMed ID: 36074075
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Nohara T, Ohno Y, Kihara A.
Impaired production of skin barrier lipid acylceramides and abnormal localization of PNPLA1 due to ichthyosis-causing mutations in PNPLA1.
J Dermatol Sci
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Lyu X, Imai S, Yamano T, Hanayama R.
Preventing SARS-CoV-2 Infection Using Anti-spike Nanobody-IFN-β Conjugated Exosomes.
Pharm Res
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PubMed ID: 36163411
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Yamamura N, Mikkaichi T, Itokawa KI, Hoshi M, Damme K, Geigner S, Baumhauer C.
Mirogabalin, a novel α2δ ligand, is not a substrate of LAT1, but of PEPT1, PEPT2, OAT1, OAT3, OCT2, MATE1 and MATE2-K.
Xenobiotica
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Kanadome T, Hayashi K, Seto Y, Eiraku M, Nakajima K, Nagai T, Matsuda T.
Development of intensiometric indicators for visualizing N-cadherin interaction across cells.
Commun Biol
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Mang D, Mayu K, Toyama T, Yamagishi T, Sato R.
BmGr4 responds to sucrose and glucose and expresses in tachykinin-related peptide-secreting enteroendocrine cells.
Insect Biochem Mol Biol
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Nakazato A, Mochizuki M, Shibuya-Takahashi R, Fujimori H, Fujii K, Saijoh S, Morita S, Yamazaki T, Imai T, Sato I, Satoh K, Yamaguchi K, Sugamura K, Yasuda J, Matsuura K, Shojaku H, Asada Y, Tamai K.
RELA is required for CD271 expression and stem-like characteristics in hypopharyngeal cancer.
Sci Rep
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Kotani N, Nakano T, Kuwahara R.
Host cell membrane proteins located near SARS-CoV-2 spike protein attachment sites are identified using proximity labeling and proteomic analysis.
J Biol Chem
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Wang TW, Johmura Y, Suzuki N, Omori S, Migita T, Yamaguchi K, Hatakeyama S, Yamazaki S, Shimizu E, Imoto S, Furukawa Y, Yoshimura A, Nakanishi M.
Blocking PD-L1-PD-1 improves senescence surveillance and ageing phenotypes.
Nature
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PubMed ID: 36323784
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Akiyama M, Unoki T, Aoki H, Nishimura A, Shinkai Y, Warabi E, Nishiyama K, Furumoto Y, Anzai N, Akaike T, Nishida M, Kumagai Y.
Cystine-dependent antiporters buffer against excess intracellular reactive sulfur species-induced stress.
Redox Biol
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Sekine W, Takenaka-Uema A, Kamiki H, Ishida H, Matsugo H, Murakami S, Horimoto T.
Adaptation of the H7N2 Feline Influenza Virus to Human Respiratory Cell Culture
Viruses
2022
14(5):1091
PubMed ID: 35632832
DOI: 10.3390/v14051091
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20971
Tatsumi A, Hirakochi H, Inoue S, Tanaka Y, Furuno H, Ikeda M, Ishibashi S, Taguchi T, Yamamoto K, Onishi I, Sachs Z, Largaespada DA, Kitagawa M, Kurata M.
Identification of NRAS Downstream Genes with CRISPR Activation Screening.
Biology (Basel)
2022
11(11)
PubMed ID: 36358254
DOI: 10.3390/biology11111551
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20975
Moriyama H, Moriyama M, Ozawa T, Tsuruta D, Hayakawa T.
Differentiation of Human Adipose-Derived Mesenchymal Stromal/Stem Cells into Insulin-Producing Cells with A Single Tet-Off Lentiviral Vector System.
Cell J
2022
24(12):705-714
PubMed ID: 36527342
DOI: 10.22074/cellj.2022.557533.1063
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20998
Ozono T, Kimura Y, Suenaga T, Beck G, Jinno J, Aguirre C, Ikenaka K, Krainc D, Mochizuki H, Arase H.
Extracellular transportation of α-synuclein by HLA class II molecules.
Biochem Biophys Res Commun
2022
644:25-33
PubMed ID: 36621149
DOI: 10.1016/j.bbrc.2022.12.082
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21033
Takahashi TM, Hirano A, Kanda T, Saito VM, Ashitomi H, Tanaka KZ, Yokoshiki Y, Masuda K, Yanagisawa M, Vogt KE, Tokuda T, Sakurai T.
Optogenetic induction of hibernation-like state with modified human Opsin4 in mice.
Cell Rep Methods
2022
2(11):100336
PubMed ID: 36452866
DOI: 10.1016/j.crmeth.2022.100336
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21037
Takahashi M, Kobayashi T, Mizuma H, Yamauchi K, Okamoto S, Okamoto K, Ishida Y, Koike M, Watanabe M, Isa T, Hioki H.
Preferential arborization of dendrites and axons of parvalbumin- and somatostatin-positive GABAergic neurons within subregions of the mouse claustrum.
Neurosci Res
2022
PubMed ID: 36574563
DOI: 10.1016/j.neures.2022.11.008
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17361
Hirose Y, Shindo N, Mori M, Onitsuka S, Isogai H, Hamada R, Hiramoto T, Ochi J, Takahashi D, Ueda T, Caaveiro JMM, Yoshida Y, Ohdo S, Matsunaga N, Toba S, Sasaki M, Orba Y, Sawa H, Sato A, Kawanishi E, Ojida A.
Discovery of Chlorofluoroacetamide-Based Covalent Inhibitors for Severe Acute Respiratory Syndrome Coronavirus 2 3CL Protease
J Med Chem
2022
65(20):13852-13865
PubMed ID: 36229406
DOI: 10.1021/acs.jmedchem.2c01081
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21141
Suenaga T, Mori Y, Suzutani T, Arase H.
Siglec-7 mediates varicella-zoster virus infection by associating with glycoprotein B.
Biochem Biophys Res Commun
2022
607:67-72
PubMed ID: 35367830
DOI: 10.1016/j.bbrc.2022.03.060
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22173
Ishibashi R, Maki R, Kitano S, Miyachi H, Toyoshima F.
Development of an in vivo cleavable donor plasmid for targeted transgene integration by CRISPR-Cas9 and CRISPR-Cas12a
Sci Rep
2022
12(1):17775
PubMed ID: 36272994
DOI: 10.1038/s41598-022-22639-6
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22174
Yim WW, Yamamoto H, Mizushima N.
A pulse-chasable reporter processing assay for mammalian autophagic flux with HaloTag
Elife
2022
11:e78923
PubMed ID: 35938926
DOI: 10.7554/eLife.78923
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22175
Matsumoto N, Sekiya M, Sun-Wada GH, Wada Y, Nakanishi-Matsui M.
The lysosomal V-ATPase a3 subunit is involved in localization of Mon1-Ccz1, the GEF for Rab7, to secretory lysosomes in osteoclasts
Sci Rep
2022
12(1):8455
PubMed ID: 35589873
DOI: 10.1038/s41598-022-12397-w
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22256
Takahashi G, Kondo D, Maeda M, Morishita Y, Miyaoka Y.
Genome editing is induced in a binary manner in single human cells
iScience
2022
25(12):105619
PubMed ID: 36483018
DOI: 10.1016/j.isci.2022.105619
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22257
Ichinose M, Kawabata M, Akaiwa Y, Shimajiri Y, Nakamura I, Tamai T, Nakamura T, Yagi Y, Gutmann B.
U-to-C RNA editing by synthetic PPR-DYW proteins in bacteria and human culture cells
Commun Biol
2022
5(1):968
PubMed ID: 36109586
DOI: 10.1038/s42003-022-03927-3
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22258
Maeda Y, Watanabe T, Izumi T, Kuriyama K, Ohno S, Fujimuro M.
Biomolecular Fluorescence Complementation Profiling and Artificial Intelligence Structure Prediction of the Kaposi's Sarcoma-Associated Herpesvirus ORF18 and ORF30 Interaction
Int J Mol Sci
2022
23(17):9647
PubMed ID: 36077046
DOI: 10.3390/ijms23179647
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22259
Sato M, Sato-Yamamoto N, Wakita A, Haraguchi M, Shimonishi M, Okuno H.
Direct Injection of Recombinant AAV-Containing Solution into the Oviductal Lumen of Pregnant Mice Caused In Situ Infection of Both Preimplantation Embryos and Oviductal Epithelium
Int J Mol Sci
2022
23(9):4897
PubMed ID: 35563284
DOI: 10.3390/ijms23094897
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22293
Maruyama T, Mano A, Ishii T, Kakinuma Y, Kaneda M.
P2X2 receptors supply extracellular choline as a substrate for acetylcholine synthesis
FEBS Open Bio
2022
12(1):250-257.
PubMed ID: 34787962
DOI: 10.1002/2211-5463.13332
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22301
Matsui Y, Mineharu Y, Noguchi Y, Hattori EY, Kubota H, Hirata M, Miyamoto S, Sugiyama H, Arakawa Y, Kamikubo Y.
Chlorambucil-conjugated PI-polyamides (Chb-M'), a transcription inhibitor of RUNX family, has an anti-tumor activity against SHH-type medulloblastoma with p53 mutatio
Biochem Biophys Res Commun
2022
620:150-157
PubMed ID: 35792512
DOI: 10.1016/j.bbrc.2022.06.090
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22321
Hatayama M, Katayama KI, Kawahara Y, Matsunaga H, Takashima N, Iwayama Y, Matsumoto Y, Nishi A, Yoshikawa T, Aruga J.
SLITRK1-mediated noradrenergic projection suppression in the neonatal prefrontal cortex
Commun Biol
2022
5(1):935
PubMed ID: 36085162
DOI: 10.1038/s42003-022-03891-y
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22429
Somiya M, Kuroda S.
Engineering of Extracellular Vesicles for Small Molecule-Regulated Cargo Loading and Cytoplasmic Delivery of Bioactive Proteins
Mol Pharm
2022
19(7):2495-2505
PubMed ID: 35594496
DOI: 10.1021/acs.molpharmaceut.2c00192
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17694
Furuta T, Yamauchi K, Okamoto S, Takahashi M, Kakuta S, Ishida Y, Takenaka A, Yoshida A, Uchiyama Y, Koike M, Isa K, Isa T, Hioki H.
Multi-scale light microscopy/electron microscopy neuronal imaging from brain to synapse with a tissue clearing method, Sca l eSF
iScience
2021
25(1):103601
PubMed ID: 35106459
DOI: 10.1016/j.isci.2021.103601
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19485
Uehara T, Sanuki R, Ogura Y, Yokoyama A, Yoshida T, Futagawa H, Yoshihashi H, Yamada M, Suzuki H, Takenouchi T, Matsubara K, Hirata H, Kosaki K, Takano-Shimizu T.
Recurrent NFIA K125E substitution represents a loss-of-function allele: Sensitive in vitro and in vivo assays for nontruncating alleles
Am J Med Genet A
2021
185(7):2084-2093
PubMed ID: 33973697
DOI: 10.1002/ajmg.a.62226
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12798
Johmura Y, Yamanaka T, Omori S, Wang TW, Sugiura Y, Matsumoto M, Suzuki N, Kumamoto S, Yamaguchi K, Hatakeyama S, Takami T, Yamaguchi R, Shimizu E, Ikeda K, Okahashi N, Mikawa R, Suematsu M, Arita M, Sugimoto M, Nakayama KI, Furukawa Y, Imoto S, Nakanishi M.
Senolysis by glutaminolysis inhibition ameliorates various age-associated disorders
Science
2021
371(6526):265-270
PubMed ID: 33446552
DOI: 10.1126/science.abb5916
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13320
Matsumoto N, Sekiya M, Fujimoto Y, Haga S, Sun-Wada GH, Wada Y, Nakanishi-Matsui M.
Functional complementation of V-ATPase a subunit isoforms in osteoclasts.
J Biochem
2021
169(4):459-466
PubMed ID: 33135054
DOI: 10.1093/jb/mvaa118
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13345
Daifu T, Mikami M, Hiramatsu H, Iwai A, Umeda K, Noura M, Kubota H, Masuda T, Furuichi K, Takasaki S, Noguchi Y, Morita K, Bando T, Hirata M, Kataoka TR, Nakahata T, Kuwahara Y, Iehara T, Hosoi H, Takita J, Sugiyama H, Adachi S, Kamikubo Y.
Suppression of malignant rhabdoid tumors through Chb-M'-mediated RUNX1 inhibition.
Pediatr Blood Cancer
2021
PubMed ID: 33180377
DOI: 10.1002/pbc.28789
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13351
Matsumoto Y, Kishida K, Matsumoto M, Matsuoka S, Kohyama M, Suenaga T, Arase H.
A TCR-like antibody against a proinsulin-containing fusion peptide ameliorates type 1 diabetes in NOD mice.
Biochem Biophys Res Commun
2021
PubMed ID: 33208230
DOI: 10.1016/j.bbrc.2020.11.019
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13463
Shota Someya et al
Tryptophan Metabolism Regulates Proliferative Capacity of Human Pluripotent Stem Cells
iScienc
2021
24
PubMed ID: 33615198
DOI: 10.1016/j.isci.2021.102090
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20008
Umaba R, Kitanishi T, Mizuseki K.
Monosynaptic connection from the subiculum to medial mammillary nucleus neurons projecting to the anterior thalamus and Gudden's ventral tegmental nucleus.
Neurosci Res
2021
PubMed ID: 33476683
DOI: 10.1016/j.neures.2021.01.006
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20053
Takafuji S, Mori T, Nishimura N, Yamamoto N, Uemura S, Nozu K, Terui K, Toki T, Ito E, Muramatsu H, Takahashi Y, Matsuo M, Yamamura T, Iijima K.
Usefulness of functional splicing analysis to confirm precise disease pathogenesis in Diamond-Blackfan anemia caused by intronic variants in RPS19.
Pediatr Hematol Oncol
2021
1-16
PubMed ID: 33622161
DOI: 10.1080/08880018.2021.1887984
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20060
Nishiike Y, Miyazoe D, Togawa R, Yokoyama K, Nakasone K, Miyata M, Kikuchi Y, Kamei Y, Todo T, Ishikawa-Fujiwara T, Ohno K, Usami T, Nagahama Y, Okubo K.
Estrogen receptor 2b is the major determinant of sex-typical mating behavior and sexual preference in medaka.
Curr Biol
2021
PubMed ID: 33639108
DOI: 10.1016/j.cub.2021.01.089
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13513
Takahashi Y, Wake H, Sakaguchi M, Yoshii Y, Teshigawara K, Wang D, Nishibori M.
Histidine-Rich Glycoprotein Stimulates Human Neutrophil Phagocytosis and Prolongs Survival through CLEC1A
J Immunol
2021
206(4):737-750
PubMed ID: 33452125
DOI: 10.4049/jimmunol.2000817
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20067
Aizawa N, Fujimori Y, Nakanishi O, Hayashi T, Goi Y, Kobayashi JI, Fujita T.
Efficacy of the combination of KPR-5714, a novel transient receptor potential melastatin 8 (TRPM8) antagonist, and β3-adrenoceptor agonist or anticholinergic agent on bladder dysfunction in rats with bladder overactivity.
Eur J Pharmacol
2021
173995
PubMed ID: 33675781
DOI: 10.1016/j.ejphar.2021.173995
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20068
Nakamura R, Oyama T, Inokuchi M, Ishikawa S, Hirata M, Kawashima H, Ikeda H, Dobashi Y, Ooi A.
Neural EGFL like 2 expressed in myoepithelial cells and suppressed breast cancer cell migration.
Pathol Int
2021
PubMed ID: 33657249
DOI: 10.1111/pin.13087
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13640
Fujita K, Koide N, Somiya M, Kuroda S, Hinuma S.
A regulatory role of scavenger receptor class B type 1 in endocytosis and lipid droplet formation induced by liposomes containing phosphatidylethanolamine in HEK293T cells
Biochim Biophys Acta Mol Cell Res
2021
1868(1):118859
PubMed ID: 32956759
DOI: 10.1016/j.bbamcr.2020.118859
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20083
Hama K, Fujiwara Y, Hayama T, Ozawa T, Nozawa K, Matsuda K, Hashiguchi Y, Yokoyama K.
Very long-chain fatty acids are accumulated in triacylglycerol and nonesterified forms in colorectal cancer tissues.
Sci Rep
2021
11(1):6163
PubMed ID: 33731797
DOI: 10.1038/s41598-021-85603-w
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20103
McKee HK, Kajiwara C, Yamaguchi T, Ishii Y, Shimizu N, Ohara A, Tateda K.
Clostridioides difficile toxins enhanced the in vitro production of CXC chemokine ligand 2 and tumor necrosis factor-α via Toll-like receptors in macrophages.
J Med Microbiol
2021
70(4)
PubMed ID: 33830910
DOI: 10.1099/jmm.0.001342
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13898
Takuma Kitanishi, Ryoko Umaba, Kenji Mizuseki
Robust information routing by dorsal subiculum neurons
Sci Adv
2021
7(11):eabf1913
PubMed ID: 33692111
DOI: 10.1126/sciadv.abf1913
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13913
Rai D, Akagi T, Shimohata A, Ishii T, Gangi M, Maruyama T, Wada-Kiyama Y, Ogiwara I, Kaneda M.
Involvement of the C-terminal domain in cell surface localization and G-protein coupling of mGluR6
J Neurochem
2021
158(4):837-848
PubMed ID: 33067823
DOI: 10.1111/jnc.15217
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20114
Ojiro I, Nishio H, Yamazaki-Ito T, Nakano S, Ito S, Toyohara Y, Hiramoto T, Terada Y, Ito K.
Trp-Trp acts as a multi-functional blocker for human bitter taste receptors, hTAS2R14, hTAS2R16, hTAS2R43, and hTAS2R46.
Biosci Biotechnol Biochem
2021
PubMed ID: 33844825
DOI: 10.1093/bbb/zbab061
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20138
Nagumo Y, Kandori S, Tanuma K, Nitta S, Chihara I, Shiga M, Hoshi A, Negoro H, Kojima T, Mathis BJ, Funakoshi Y, Nishiyama H.
PLD1 promotes tumor invasion by regulation of MMP-13 expression via NF-κB signaling in bladder cancer.
Cancer Lett
2021
511:15-25
PubMed ID: 33945837
DOI: 10.1016/j.canlet.2021.04.014
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20147
Kariya Y, Oyama M, Suzuki T, Kariya Y.
αvβ3 Integrin induces partial EMT independent of TGF-β signaling.
Commun Biol
2021
4(1):490
PubMed ID: 33883697
DOI: 10.1038/s42003-021-02003-6
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14182
Somiya M, Kuroda S.
Real-Time Luminescence Assay for Cytoplasmic Cargo Delivery of Extracellular Vesicles
Anal Chem
2021
93(13):5612-5620
PubMed ID: 33759512
DOI: 10.1021/acs.analchem.1c00339
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20150
Takeshita M, Suzuki K, Nakazawa M, Kamata H, Ishii M, Oyamada Y, Oshima H, Takeuchi T.
Antigen-driven autoantibody production in lungs of interstitial lung disease with autoimmune disease.
J Autoimmun
2021
121:102661
PubMed ID: 34034155
DOI: 10.1016/j.jaut.2021.102661
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20155
Sahoo PR, Kowada T, Mizukami S.
Long-Term Mg2+ Imaging in Live Cells with a Targetable Fluorescent Probe.
Methods Mol Biol
2021
2274:237-243
PubMed ID: 34050476
DOI: 10.1007/978-1-0716-1258-3_20
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20157
Matsui H, Ito J, Matsui N, Uechi T, Onodera O, Kakita A.
Cytosolic dsDNA of mitochondrial origin induces cytotoxicity and neurodegeneration in cellular and zebrafish models of Parkinson's disease.
Nat Commun
2021
12(1):3101
PubMed ID: 34035300
DOI: 10.1038/s41467-021-23452-x
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20158
Osakabe K, Wada N, Murakami E, Miyashita N, Osakabe Y.
Genome editing in mammalian cells using the CRISPR type I-D nuclease.
Nucleic Acids Res
2021
PubMed ID: 34076237
DOI: 10.1093/nar/gkab348
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20165
Kobayashi JI, Hirasawa H, Fujimori Y, Nakanishi O, Kamada N, Ikeda T, Yamamoto A, Kanbe H.
Identification of N-acyl-N-indanyl-α-phenylglycinamides as selective TRPM8 antagonists designed to mitigate the risk of adverse effects.
Bioorg Med Chem
2021
30:115903
PubMed ID: 33333445
DOI: 10.1016/j.bmc.2020.115903
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14478
Yamanaka D, Shoda M, Matsubara T, Ishibashi KI, Motoi A, Motoi R, Motoi M, Ohno N, Adachi Y.
Open-Label Study of the Influence of Food Containing the Royal Sun Mushroom, Agaricus brasiliensis KA21 (Agaricomycetes), on β-Glucan-Specific Antibody Production in Healthy Human Volunteers
Int J Med Mushrooms
2021
23(2):13-28
PubMed ID: 33639078
DOI: 10.1615/IntJMedMushrooms.2020037471
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20199
Tomita T, Kato M, Mishima T, Matsunaga Y, Sanjo H, Ito KI, Minagawa K, Matsui T, Oikawa H, Takahashi S, Takao T, Iwai N, Mino T, Takeuchi O, Maru Y, Hiratsuka S.
Extracellular mRNA transported to the nucleus exerts translation-independent function.
Nat Commun
2021
12(1):3655
PubMed ID: 34135341
DOI: 10.1038/s41467-021-23969-1
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20200
Kuwabara S, Tanimoto Y, Okutani M, Jie M, Haseda Y, Kinugasa-Katayama Y, Aoshi T.
Microfluidics sorting enables the isolation of an intact cellular pair complex of CD8+ T cells and antigen-presenting cells in a cognate antigen recognition-dependent manner.
PLoS One
2021
16(6):e0252666
PubMed ID: 34125844
DOI: 10.1371/journal.pone.0252666
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20216
Niinae T, Imami K, Sugiyama N, Ishihama Y.
Identification of Endogenous Kinase Substrates by Proximity Labeling Combined with Kinase Perturbation and Phosphorylation Motifs.
Mol Cell Proteomics
2021
100119
PubMed ID: 34186244
DOI: 10.1016/j.mcpro.2021.100119
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14782
Uemura K, Sasaki M, Sanaki T, Toba S, Takahashi Y, Orba Y, Hall WW, Maenaka K, Sawa H, Sato A.
MRC5 cells engineered to express ACE2 serve as a model system for the discovery of antivirals targeting SARS-CoV-2
Sci Rep
2021
11(1):5376
PubMed ID: 33686154
DOI: 10.1038/s41598-021-84882-7
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14827
iu Y, Soh WT, Kishikawa JI, Hirose M, Nakayama EE, Li S, Sasai M, Suzuki T, Tada A, Arakawa A, Matsuoka S, Akamatsu K, Matsuda M, Ono C, Torii S, Kishida K, Jin H, Nakai W, Arase N, Nakagawa A, Matsumoto M, Nakazaki Y, Shindo Y, Kohyama M, Tomii K, Ohmura K, Ohshima S, Okamoto T, Yamamoto M, Nakagami H, Matsuura Y, Nakagawa A, Kato T, Okada M, Standley DM, Shioda T, Arase H.
An infectivity-enhancing site on the SARS-CoV-2 spike protein targeted by antibodies
Cell
2021
184(13):3452-3466.e18
PubMed ID: 34139176
DOI: 10.1016/j.cell.2021.05.032
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20233
Koshizuka T, Kondo H, Kato H, Takahashi K.
Human cytomegalovirus UL42 protein inhibits the degradation of glycoprotein B through inhibition of Nedd4 family ubiquitin E3 ligases.
Microbiol Immunol
2021
PubMed ID: 34260096
DOI: 10.1111/1348-0421.12932
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20240
Kaku T, Sugiura K, Entani T, Osabe K, Nagai T.
Enhanced brightness of bacterial luciferase by bioluminescence resonance energy transfer.
Sci Rep
2021
11(1):14994
PubMed ID: 34294849
DOI: 10.1038/s41598-021-94551-4
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14939
Shuji Hinuma, Kazuyo Fujita, Shun’ichi Kuroda
Binding of Nanoparticles Harboring Recombinant Large Surface Protein of Hepatitis B Virus to Scavenger Receptor Class B Type 1
Viruses
2021
13:1334
PubMed ID: 34372540
DOI: 10.3390/v13071334
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20244
Yoshioka K, Obara K, Oikawa S, Uemura K, Yamaguchi A, Fujisawa K, Hanazawa H, Fujiwara M, Endoh T, Suzuki T, Regadera MD, Ito D, Ou G, Xu K, Tanaka Y.
Docosahexaenoic acid inhibits U46619- and prostaglandin F2α-induced pig coronary and basilar artery contractions by inhibiting prostanoid TP receptors.
Eur J Pharmacol
2021
174371
PubMed ID: 34329614
DOI: 10.1016/j.ejphar.2021.174371
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20272
Ma Y, Yoshida T, Matoba K, Kida K, Shintani R, Piao Y, Jin J, Nishino T, Hanayama R.
Identification of small compounds regulating the secretion of extracellular vesicles via a TIM4-affinity ELISA.
Sci Rep
2021
11(1):13471
PubMed ID: 34188113
DOI: 10.1038/s41598-021-92860-2
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15168
Hangai S, Kawamura T, Kimura Y, Chang CY, Hibino S, Yamamoto D, Nakai Y, Tateishi R, Oshima M, Oshima H, Kodama T, Moriya K, Koike K, Yanai H, Taniguchi T.
Orchestration of myeloid-derived suppressor cells in the tumor microenvironment by ubiquitous cellular protein TCTP released by tumor cells
Nat Immunol
2021
22(8):947-957
PubMed ID: 34239121
DOI: 10.1038/s41590-021-00967-5
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20282
Nakanishi E, Uemura N, Akiyama H, Kinoshita M, Masanori S, Taruno Y, Yamakado H, Matsuzawa SI, Takeda S, Hirabayashi Y, Takahashi R.
Impact of Gba2 on neuronopathic Gaucher's disease and α-synuclein accumulation in medaka (Oryzias latipes).
Mol Brain
2021
14(1):80
PubMed ID: 33971917
DOI: 10.1186/s13041-021-00790-x
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20283
Sakoguchi A, Saito F, Hirayasu K, Shida K, Matsuoka S, Itagaki S, Nakai W, Kohyama M, Suenaga T, Iwanaga S, Horii T, Arase H.
Plasmodium falciparum RIFIN is a novel ligand for inhibitory immune receptor LILRB2.
Biochem Biophys Res Commun
2021
548:167-173
PubMed ID: 33647792
DOI: 10.1016/j.bbrc.2021.02.033
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20298
Nagano C, Takaoka Y, Kamei K, Hamada R, Ichikawa D, Tanaka K, Aoto Y, Ishiko S, Rossanti R, Sakakibara N, Okada E, Horinouchi T, Yamamura T, Tsuji Y, Noguchi Y, Ishimori S, Nagase H, Ninchoji T, Iijima K, Nozu K.
Genotype-Phenotype Correlation in WT1 Exon 8 to 9 Missense Variants.
Kidney Int Rep
2021
6(8):2114-2121
PubMed ID: 34386660
DOI: 10.1016/j.ekir.2021.05.009
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20322
Fujisawa S, Qiu H, Nozaki S, Chiba S, Katoh Y, Nakayama K.
ARL3 and ARL13B GTPases participate in distinct steps of INPP5E targeting to the ciliary membrane.
Biol Open
2021
PubMed ID: 34447983
DOI: 10.1242/bio.058843
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15284
Yoshiko Iizuka, Kinuko Inomata, Risako Nohara, Akimitsu Miyawaki and Yoshifumi Watanabe
Activation of intracellular antioxidant master gene Nrf2 by the extracts of Garcinia subelliptica, Ocimum gratissimum L., and Plectranthus ornatus
International Journal of Herbal Medicine
2021
9(3):54-60
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15524
Fukasawa K, Kadota T, Horie T, Tokumura K, Terada R, Kitaguchi Y, Park G, Ochiai S, Iwahashi S, Okayama Y, Hiraiwa M, Yamada T, Iezaki T, Kaneda K, Yamamoto M, Kitao T, Shirahase H, Hazawa M, Wong RW, Todo T, Hirao A, Hinoi E.
CDK8 maintains stemness and tumorigenicity of glioma stem cells by regulating the c-MYC pathway
Oncogene
2021
40(15):2803-2815
PubMed ID: 33727660
DOI: 10.1038/s41388-021-01745-1
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20354
Noguchi T, Nakamura K, Satoda Y, Katoh Y, Nakayama K.
CCRK/CDK20 regulates ciliary retrograde protein trafficking via interacting with BROMI/TBC1D32.
PLoS One
2021
16(10):e0258497
PubMed ID: 34624068
DOI: 10.1371/journal.pone.0258497
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20356
Yasumura M, Hagiwara A, Hida Y, Ohtsuka T.
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Treatment of Retinoblastoma 1-Intact Hepatocellular Carcinoma With Cyclin-Dependent Kinase 4/6 Inhibitor Combination Therapy
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PACAP-PAC1 Signaling Regulates Serotonin 2A Receptor Internalization
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Front Endocrinol (Lausanne)
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iPSC-Derived Neoantigen-Specific CTL Therapy for Ewing Sarcoma
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Structural Insight into the Interaction of Sendai Virus C Protein with Alix To Stimulate Viral Budding
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Positive feedback regulation between USP15 and ERK2 inhibits osteoarthritis progression through TGF-β/SMAD2 signaling
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Discovery of a transdermally deliverable pentapeptide for activating AdipoR1 to promote hair growth
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Cytotechnology
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V-ATPase a3 Isoform Mutations Identified in Osteopetrosis Patients Abolish Its Expression and Disrupt Osteoclast Function
Exp Cell Res
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17β-Hydroxysteroid Dehydrogenase Type 12a Responsible for Testicular 11-ketotestosterone Synthesis in the Japanese Eel, Anguilla Japonica
J Steroid Biochem Mol Biol
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HTLV-1 Induces T Cell Malignancy and Inflammation by Viral Antisense Factor-Mediated Modulation of the Cytokine Signaling
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An ultra-stable cytoplasmic antibody engineered for in vivo applications.
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Cell Rep
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Novel Nile tilapia Neu1 sialidases: Molecular cloning and biochemical characterization of the sialidases Neu1a and Neu1b.
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Kampo medicines, Rokumigan, Hachimijiogan, and Goshajinkigan, significantly inhibit glucagon-induced CREB activation.
Heliyon
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The enantiomer pair of 24S- and 24R-hydroxycholesterol differentially alter activity of large-conductance Ca 2+ -dependent K + (slo1 BK) channel
Chirality
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Polarization-sensitive optical coherence tomography for estimating relative melanin content of autologous induced stem-cell derived retinal pigment epithelium.
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Homeostatic and pathogenic roles of GM3 ganglioside molecular species in TLR4 signaling in obesity.
EMBO J
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AirID, a novel proximity biotinylation enzyme, for analysis of protein-protein interactions.
Elife
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Neuroplastinβ-mediated upregulation of solute carrier family 22 member 18 antisense (SLC22A18AS) plays a crucial role in the epithelial-mesenchymal transition, leading to lung cancer cells' enhanced motility.
Biochem Biophys Rep
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Park M, Miyoshi C, Fujiyama T, Kakizaki M, Ikkyu A, Honda T, Choi J, Asano F, Mizuno S, Takahashi S, Yanagisawa M, Funato H.
Loss of the conserved PKA sites of SIK1 and SIK2 increases sleep need.
Sci Rep
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Pathogenic evaluation of synonymous COL4A5 variants in X-linked Alport syndrome using a minigene assay.
Mol Genet Genomic Med
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Asbestos conceives Fe(II)-dependent mutagenic stromal milieu through ceaseless macrophage ferroptosis and β-catenin induction in mesothelium.
Redox Biol
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Yamashita J, Takeuchi A, Hosono K, Fleming T, Nagahama Y, Okubo K.
Male-predominant galanin mediates androgen-dependent aggressive chases in medaka.
Elife
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Genome editing with the donor plasmid equipped with synthetic crRNA-target sequence.
Sci Rep
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Huetter J, Gritzan U, Gutcher I, Doecke WD, Luetke-Eversloh MV, Golfier S, Roider HG, Frisk AL, Hunter J, Pow A, Drake A, Levine Z, Levy O, Azulay M, Barbiro I, Cojocaru G, Vaknin I, Kreft B, Roese L.
Characterization of BAY 1905254, an Immune Checkpoint Inhibitor Targeting the Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2).
Cancer Immunol Res
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Kakizawa S, Kishimoto Y, Yamamoto S, Onga K, Yasuda K, Miyamoto Y, Watanabe M, Sakai R, Mori N.
Functional maintenance of calcium store by ShcB adaptor protein in cerebellar Purkinje cells.
Sci Rep
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Ago Y, Otsuka H, Sasai H, Abdelkreem E, Nakama M, Aoyama Y, Matsumoto H, Fujiki R, Ohara O, Akiyama K, Fukui K, Watanabe Y, Nakajima Y, Ohnishi H, Ito T, Fukao T.
Japanese patients with mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase deficiency: In vitro functional analysis of five novel HMGCS2 mutations.
Exp Ther Med
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Kinoshita N, Huang AJY, McHugh TJ, Miyawaki A, Shimogori T.
Diffusible GRAPHIC to visualize morphology of cells after specific cell-cell contact.
Sci Rep
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Kitao T, Taguchi K, Seto S, Arasaki K, Ando H, Nagai H, Kubori T.
Legionella Manipulates Non-canonical SNARE Pairing Using a Bacterial Deubiquitinase.
Cell Rep
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Arai Y, Kawashita N, Elgendy EM, Ibrahim MS, Daidoji T, Ono T, Takagi T, Nakaya T, Matsumoto K, Watanabe Y.
PA Mutations Inherited during Viral Evolution Act Cooperatively To Increase Replication of Contemporary H5N1 Influenza Virus with an Expanded Host Range.
J Virol
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Okamura M, Shizu R, Abe T, Kodama S, Hosaka T, Sasaki T, Yoshinari K.
PXR Functionally Interacts with NF-κB and AP-1 to Downregulate the Inflammation-Induced Expression of Chemokine CXCL2 in Mice.
Cells
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PubMed ID: 33076328
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Kato M, Onoyama I, Kawakami M, Yoshida S, Kawamura K, Kodama K, Hori E, Cui L, Matsumura Y, Yagi H, Asanoma K, Yahata H, Itakura A, Takeda S, Kato K.
Downregulation of 5-hydroxymethylcytosine is associated with the progression of cervical intraepithelial neoplasia.
PLoS One
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Yamazaki T, Takahashi C, Taniguchi Y, Narukawa M, Misaka T, Ano Y.
Bitter taste receptor activation by hop-derived bitter components induces gastrointestinal hormone production in enteroendocrine cells.
Biochem Biophys Res Commun
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Osakabe K, Wada N, Miyaji T, Murakami E, Marui K, Ueta R, Hashimoto R, Abe-Hara C, Kong B, Yano K, Osakabe Y.
Genome editing in plants using CRISPR type I-D nuclease.
Commun Biol
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Shoji S, Hanada K, Takahashi M, Watanabe K, Yonemochi M, Tomabechi Y, Shirouzu M.
The NF-κB regulator IκBβ exhibits different molecular interactivity and phosphorylation status from IκBα in an IKK2-catalysed reaction
FEBS Lett
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Tohama T, Sakari M, Tsukahara T.
Development of a Single Construct System for Site-Directed RNA Editing Using MS2-ADAR
Int J Mol Sci
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Harada M, Nghia VT, Nakao A, Tanigaki R, Fukuoka N, Nishida A, Kataoka T.
Eomesodermin promotes interaction of RelA and NFATc2 with the Ifng promoter and multiple conserved noncoding sequences across the Ifng locus in mouse lymphoma BW5147 cells
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Suzuki T, Morimoto N, Akaike A, Osakada F.
Multiplex Neural Circuit Tracing With G-Deleted Rabies Viral Vectors
Front Neural Circuits
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Overexpression of neural miRNAs miR-9/9* and miR-124 suppresses differentiation to Müller glia and promotes differentiation to neurons in mouse retina in vivo
Genes Cells
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Microbiol Immunol
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Cancer Res
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Effective RNA Knockdown Using CRISPR-Cas13a and Molecular Targeting of the EML4-ALK Transcript in H3122 Lung Cancer Cells
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Cell Struct Funct
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Synthesis of C12-Keto Saxitoxin Derivatives with Unusual Inhibitory Activity Against Voltage-Gated Sodium Channels
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Mol Med Rep
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Glycobiology
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Mol. Cell. Biochem.
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J. Biol. Chem.
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Elife
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Proton pumping V-ATPase inhibitor bafilomycin A1 affects Rab7 lysosomal localization and abolishes anterograde trafficking of osteoclast secretory lysosomes.
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Type I interferon protects neurons from prions in in vivo models.
Brain
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Degradation of p47 by autophagy contributes to CADM1 overexpression in ATLL cells through the activation of NF-κB.
Sci Rep
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Melanoma cell adhesion molecule is the driving force behind the dissemination of melanoma upon S100A8/A9 binding in the original skin lesion.
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Mol Cell
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Neoplasia
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Evolutionary and Functional Diversity of the 5' Untranslated Region of Enterovirus D68: Increased Activity of the Internal Ribosome Entry Site of Viral Strains during the 2010s.
Viruses
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Ishii J, Suzuki A, Kimura T, Tateyama M, Tanaka T, Yazawa T, Arimasu Y, Chen IS, Aoyama K, Kubo Y, Saitoh S, Mizuno H, Kamma H.
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Commun Biol
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Identification of intermediate-sized deletions and inference of their impact on gene expression in a human population.
Genome Med
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Single cell RNA-sequencing identified Dec2 as a suppressive factor for spermatogonial differentiation by inhibiting Sohlh1 expression.
Sci Rep
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Quantitation of the neural silencing activity of anion channelrhodopsins in Caenorhabditis elegans and their applicability for long-term illumination.
Sci Rep
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RNA
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Kamiki H, Matsugo H, Ishida H, Kobayashi-Kitamura T, Sekine W, Takenaka-Uema A, Murakami S, Horimoto T.
Adaptation of H3N2 canine influenza virus to feline cell culture.
PLoS ONE
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Res. Vet. Sci.
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Zoolog Sci
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Exp Parasitol
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Induction of Lipid Droplets in Non-Macrophage Cells as Well as Macrophages by Liposomes and Exosomes
Biochem Biophys Res Commun
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Functional Analysis of an Inducible Promoter Driven by Activation Signals from a Chimeric Antigen Receptor
Mol Ther Oncolytics
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Arisa Mitani, Takeshi Kobayashi, Yasuhito Hayashi, Natsuki Matsushita, Sachi Matsushita, Saori Nakao, Naoko Takahira, Atsushi Shiraishi, Yuichi Ohashi
Characterization of doxycycline-dependent inducible Simian Virus 40 large T antigen immortalized human conjunctival epithelial cell line
PLoS One
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Nobuyoshi Tajima, Liu Xiaoyan, Makoto Taniguchi, Nobuo Kato
24S-hydroxycholesterol alters activity of large-conductance Ca 2+-dependent K + (slo1 BK) channel through intercalation into plasma membrane
Biochim Biophys Acta Mol Cell Biol Lipids
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Granzyme A Stimulates pDCs to Promote Adaptive Immunity via Induction of Type I IFN
Front Immunol
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Expression of Oncofetal Antigen 5T4 in Murine Taste Papillae
Front Cell Neurosci
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The regulation of NDRG2 expression during ATLL development after HTLV-1 infection
Biochim Biophys Acta Mol Basis Dis
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Possible involvement of the competition for the transcriptional coactivator glucocorticoid receptor-interacting protein 1 in the inflammatory signal-dependent suppression of PXR-mediated CYP3A induction in vitro
Drug Metab Pharmacokinet
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Mitsui Y, Tomonobu N, Watanabe M, Kinoshita R, Sumardika IW, Youyi C, Murata H, Yamamoto KI, Sadahira T, Rodrigo AGH, Takamatsu H, Araki K, Yamauchi A, Yamamura M, Fujiwara H, Inoue Y, Futami J, Saito K, Iioka H, Kondo E, Nishibori M, Toyooka S, Yamamoto Y, Nasu Y, Sakaguchi M.
Upregulation of Mobility in Pancreatic Cancer Cells by Secreted S100A11 Through Activation of Surrounding Fibroblasts
Oncol Res
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Quantitative analysis of the effects of nicotinamide phosphoribosyltransferase induction on the rates of NAD+ synthesis and breakdown in mammalian cells using stable isotope-labeling combined with mass spectrometry
PLoS One
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Mechanism underlying the retarded nuclear translocation of androgen receptor splice variants
Sci China Life Sci
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Serum Nardilysin, a Surrogate Marker for Epithelial-Mesenchymal Transition, Predicts Prognosis of Intrahepatic Cholangiocarcinoma after Surgical Resection
Clin Cancer Res
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Development of Immortalized Human Tumor Endothelial Cells from Renal Cancer
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Neuroplastin-β mediates S100A8/A9-induced lung cancer disseminative progression
Mol Carcinog
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JCI Insight
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Sci Rep
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Transl Vis Sci Technol
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Genes Cells
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CNPY2 inhibits MYLIP-mediated AR protein degradation in prostate cancer cells.
Oncotarget
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A Split-Luciferase-Based Trimer Formation Assay as a High-throughput Screening Platform for Therapeutics in Alport Syndrome.
Cell Chem Biol
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Asuka Yoshida, Ryoko Kawabata, Tomoyuki Honda, Kouji Sakai, Yasushi Ami, Takemasa Sakaguchi, Takashi Irie
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J Virol
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Anti-tumor efficacy of a novel CLK inhibitor via targeting RNA splicing and MYC-dependent vulnerability
EMBO Mol Med
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A novel fatty acid-binding protein 5-estrogen-related receptor α signaling pathway promotes cell growth and energy metabolism in prostate cancer cells
Oncotarget
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Structural alteration of DNA induced by viral protein R of HIV-1 triggers the DNA damage response
Retrovirology
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MTSS1 Regulation of Actin-Nucleating Formin DAAM1 in Dendritic Filopodia Determines Final Dendritic Configuration of Purkinje Cells
Cell Rep
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Essential Role of the a3 Isoform of V-ATPase in Secretory Lysosome Trafficking via Rab7 Recruitmen
Sci Rep
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Sci Rep
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Immune evasion of Plasmodium falciparum by RIFIN via inhibitory receptors.
Nature
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Periostin is required for matricellular localization of CCN3 in periodontal ligament of mice.
J Cell Commun Signal
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EPSIN 3, A Novel p53 Target, Regulates the Apoptotic Pathway and Gastric Carcinogenesis.
Neoplasia
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SRSF1-3 contributes to diversification of the immunoglobulin variable region gene by promoting accumulation of AID in the nucleus.
Biochem. Biophys. Res. Commun.
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Discovery of a novel antiviral agent targeting the nonstructural protein 4 (nsP4) of chikungunya virus.
Virology
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Elife
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Identification of biallelic EXTL3 mutations in a novel type of spondylo-epi-metaphyseal dysplasia.
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BMC Mol. Biol.
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Hiwa R, Ohmura K, Arase N, Jin H, Hirayasu K, Kohyama M, Suenaga T, Saito F, Terao C, Atsumi T, Iwatani H, Mimori T, Arase H.
Myeloperoxidase/HLA Class II Complexes Recognized by Autoantibodies in Microscopic Polyangiitis.
Arthritis Rheumatol
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Regulation of tubular recycling endosome biogenesis by the p53-MICALL1 pathway.
Int. J. Oncol.
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Paradoxical enhancement of leukemogenesis in acute myeloid leukemia with moderately attenuated RUNX1 expressions.
Blood Adv
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Structural analysis of the STAT1:STAT2 heterodimer revealed the mechanism of Sendai virus C protein-mediated blockade of type 1 interferon signaling.
J. Biol. Chem.
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FAD influx enhances neuronal differentiation of human neural stem cells by facilitating nuclear localization of LSD1.
FEBS Open Bio
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Yamamura T, Nozu K, Miyoshi Y, Nakanishi K, Fujimura J, Horinouchi T, Minamikawa S, Mori N, Fujimaru R, Nakanishi K, Ninchoji T, Kaito H, Mariko TI, Morioka I, Matsuo M, Iijima K.
An in vitro splicing assay reveals the pathogenicity of a novel intronic variant in ATP6V0A4 for autosomal recessive distal renal tubular acidosis.
BMC Nephrol
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Suzuki T, Maeda S, Furuhata E, Shimizu Y, Nishimura H, Kishima M, Suzuki H.
A screening system to identify transcription factors that induce binding site-directed DNA demethylation.
Epigenetics Chromatin
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Shichita T, Ito M, Morita R, Komai K, Noguchi Y, Ooboshi H, Koshida R, Takahashi S, Kodama T, Yoshimura A.
MAFB prevents excess inflammation after ischemic stroke by accelerating clearance of damage signals through MSR1.
Nat. Med.
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The distribution of vinculin to lipid rafts plays an important role in sensing stiffness of extracellular matrix.
Biosci Biotechnol Biochem
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Jaerin Sohn, Megumu Takahashi, Shinichiro Okamoto, Yoko Ishida, Takahiro Furuta, Hiroyuki Hioki
A Single Vector Platform for High-Level Gene Transduction of Central Neurons: Adeno-Associated Virus Vector Equipped With the Tet-Off System
PLoS One
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Shigenori Inagaki, Hidekazu Tsutsui, Kazushi Suzuki, Masakazu Agetsuma, Yoshiyuki Arai, Yuka Jinno, Guirong Bai, Matthew J Daniels, Yasushi Okamura, Tomoki Matsuda, Takeharu Nagai
Genetically encoded bioluminescent voltage indicator for multi-purpose use in wide range of bioimaging
Sci Rep
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Establishment of highly metastatic KRAS mutant lung cancer cell sublines in long-term three-dimensional low attachment cultures
PLoS Onec
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Fujitani M, Zhang S, Fujiki R, Fujihara Y, Yamashita T.
A chromosome 16p13.11 microduplication causes hyperactivity through dysregulation of miR-484/protocadherin-19 signaling
Mol Psychiatry
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Sustained Activation of the Unfolded Protein Response Induces Cell Death in Fuchs' Endothelial Corneal Dystrophy
Invest Ophthalmol Vis Sci
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58(9):3697-3707
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Senga Y, Imamura H, Miyafusa T, Watanabe H, Honda S.
AlphaScreen-based homogeneous assay using a pair of 25-residue artificial proteins for high-throughput analysis of non-native IgG
Sci Rep
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Endo H, Tanaka S, Imamura K, Adegawa S, Kikuta S, Sato R.
Cry toxin specificities of insect ABCC transporters closely related to lepidopteran ABCC2 transporters
Peptides
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Kano D, Nakagami Y, Kurihara H, Hosokawa S, Zenda S, Kusumoto M, Fujii H, Kaneta T, Saito S, Uesawa Y, Kagaya H.
Development of a double-stranded siRNA labelling method by using 99m Tc and single photon emission computed tomography imaging
J Drug Target
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Tsukamoto T, Chiba Y, Wakamori M, Yamada T, Tsunogae S, Cho Y, Sakakibara R, Imazu T, Tokoro S, Satake Y, Adachi M, Nishikawa T, Yotsu-Yamashita M, Konoki K.
Differential binding of tetrodotoxin and its derivatives to voltage-sensitive sodium channel subtypes (Na v 1.1 to Na v 1.7)
Br J Pharmacol
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Wu DC, Wang SSW, Liu CJ, Wuputra K, Kato K, Lee YL, Lin YC, Tsai MH, Ku CC, Lin WH, Wang SW, Kishikawa S, Noguchi M, Wu CC, Chen YT, Chai CY, Lin CS, Kuo KK, Yang YH, Miyoshi H, Nakamura Y, Saito S, Nagata K, Lin CS, Yokoyama KK.
Reprogramming Antagonizes the Oncogenicity of HOXA13-Long Noncoding RNA HOTTIP Axis in Gastric Cancer Cells
Stem Cells
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35(10):2115-2128
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Kikuta S, Watanabe SJ, Sato R, Gusev O, Nesmelov A, Sogame Y, Cornette R, Kikawada T.
Towards water-free biobanks: long-term dry-preservation at room temperature of desiccation-sensitive enzyme luciferase in air-dried insect cells
Sci Rep
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Cancer Microenviron
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DOI: 10.1158/1078-0432.CCR-06-0449
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6478
Nakatani S, Mano H, Ryanghyok IM, Shimizu J, Wada M.
Excess magnesium inhibits excess calcium-induced matrix-mineralization and production of matrix gla protein (MGP) by ATDC5 cells.
Biochem Biophys Res Commun
2006
348(3):1157-62
PubMed ID: 16904632
DOI: 10.1016/j.bbrc.2006.07.180
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