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Cell No. : Cell Name
RCB2202 : 293T  update : 2024/09/25
CommentA subline of 293. Expressing SV40 large T antigen.
Comment from the depositor
Terms and conditionsThere is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC.
Remarks
Order Form Order Form(C-0005.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)  
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
Basic information Depositor Miyoshi, Hiroyuki
Year of deposit 2005
Original cell HEK293
Animal _human < Mammals
Genus Homo
Species sapiens
Age at sampling embryo
Tissue kidney
Classification transformed
Recombinant recombinant
Exogene SV40 large T antigen
Lifespan infinite
Morphology epithelial-like
Cellosaurus(Expasy) CVCL_0063
deposit info
lot info
Medium Medium List
Culture type Adherent cells
Culture medium DMEM (low glucose) + 10% FBS (heat inactivated)
Antibiotics Free
Passage method 0.25% Trypsin
Culture information Passage ratio 1 : 10 split
SC frequency Subculture : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
Animal PCR OK
STR(human) OK
Images
deposit info
lot info
Reference information Reference 4
User's Publication 505


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Reference
3489  DuBridge RB, Tang P, Hsia HC, Leong PM, Miller JH, Calos MP.  Analysis of mutation in human cells by using an Epstein-Barr virus shuttle system.  Mol Cell Biol  1987  7(1):379-87  PubMed ID: 3031469   DOI: 10.1128/mcb.7.1.379
4972  Graham FL, Harrison T, Williams J.  Defective transforming capacity of adenovirus type 5 host-range mutants.  Virology  1978  86(1):10-21  PubMed ID: 664220   DOI: 10.1016/0042-6822(78)90003-x
2415  Harrison T, Graham F, Williams J  Host-range mutants of adenovirus type 5 defective for growth in HeLa cells.  Virology  1977  77:319-29  PubMed ID: 841862   DOI: 10.1016/0042-6822(77)90428-7
2414  Graham, F L, Smiley J, Russell, W C, Nairn R  Characteristics of a human cell line transformed by DNA from human adenovirus type 5.  J Gen Virol  1977  36:59-74  PubMed ID: 886304   DOI: 10.1099/0022-1317-36-1-59

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User's Publication
19760  etta Takahashi, Nahoko Tomonobu, Rie Kinoshita, Ken-ichi Yamamoto, Hitoshi Murata, Ni Luh Gede Yoni Komalasari, Youyi Chen, Fan Jiang, Yuma Gohara, Toshiki Ochi, I Made Winarsa Ruma, I Wayan Sumardika, Jin Zhou, Tomoko Honjo, Yoshihiko Sakaguchi, Akira Yamauchi, Futoshi Kuribayashi, Eisaku Kondo, Yusuke Inoue, Junichiro Futami, Shinichi Toyooka, Yoshito Zamami, Masakiyo Sakaguchi  Lysyl oxidase-like 4 promotes the invasiveness of triple-negative breast cancer cells by orchestrating the invasive machinery formed by annexin A2 and S100A11 on the cell surface  Frontiers in Oncology  2024  14    DOI: 10.3389/fonc.2024.1371342
19794  Nakanishi-Matsui M, Matsumoto N, Sun-Wada GH, Wada Y.  Role of the Cytosolic Domain of the a3 Subunit of V-ATPase in the Interaction with Rab7 and Secretory Lysosome Trafficking in Osteoclasts  Biol Pharm Bull  2024  47(1):339-344  PubMed ID: 38296463   DOI: 10.1248/bpb.b23-00833
19818  Gong L, Voon DC, Nakayama J, Takahashi C, Kohno S.  RB1 loss induces quiescent state through downregulation of RAS signaling in mammary epithelial cells  Cancer Sci  2024  Mar 11  PubMed ID: 38468443   DOI: 10.1111/cas.16122
21591  Katayama M, Murakami S, Ishida H, Matsugo H, Sekine W, Ohira K, Takenaka-Uema A, Horimoto T.  Antigenic commonality and divergence of hemagglutinin-esterase-fusion protein among influenza D virus lineages revealed using epitope mapping.  J Virol  2024  e0190823  PubMed ID: 38345383   DOI: 10.1128/jvi.01908-23
21592  Ito F, Yanatori I, Kato K, Toyokuni S.  Protocol for the isolation of GFP-expressing ferroptosis-dependent extracellular vesicles in in vitro cell culture models.  STAR Protoc  2024  5(1):102892  PubMed ID: 38363686   DOI: 10.1016/j.xpro.2024.102892
21618  Kohyanagi N, Kitamura N, Ikeda S, Shibutani S, Sato K, Ohama T.  PP2A inhibitor SET promotes mTORC1 and Bmi1 signaling through Akt activation and maintains the colony-formation ability of cancer cells.  J Biol Chem  2024  300(1):105584  PubMed ID: 38141761   DOI: 10.1016/j.jbc.2023.105584
21654  Kobayashi H, Shiba T, Yoshida T, Bolidong D, Kato K, Sato Y, Mochizuki M, Seto T, Kawashiri S, Hanayama R.  Precise analysis of single small extracellular vesicles using flow cytometry.  Sci Rep  2024  14(1):7465  PubMed ID: 38553534   DOI: 10.1038/s41598-024-57974-3
21667  Kim YJ, Tohyama S, Nagashima T, Nagase M, Hida Y, Hamada S, Watabe AM, Ohtsuka T.  A light-controlled phospholipase C for imaging of lipid dynamics and controlling neural plasticity.  Cell Chem Biol  2024    PubMed ID: 38582083   DOI: 10.1016/j.chembiol.2024.03.001
21699  Suzuki N, Konuma T, Ikegami T, Akashi S.  Biophysical insights into the dimer formation of human Sirtuin 2.  Protein Sci  2024  33(5):e4994  PubMed ID: 38647411   DOI: 10.1002/pro.4994
21733  Fujii T, Liang L, Nakayama K, Katoh Y.  Defects in diffusion barrier function of ciliary transition zone caused by ciliopathy variations of TMEM218.  Hum Mol Genet  2024    PubMed ID: 38751342   DOI: 10.1093/hmg/ddae083
21738  Otsuka Y, Imamura K, Oishi A, Asakawa K, Kondo T, Nakai R, Suga M, Inoue I, Sagara Y, Tsukita K, Teranaka K, Nishimura Y, Watanabe A, Umeyama K, Okushima N, Mitani K, Nagashima H, Kawakami K, Muguruma K, Tsujikawa A, Inoue H.  Phototoxicity avoidance is a potential therapeutic approach for retinal dystrophy caused by EYS dysfunction  JCI Insight  2024  9(8):e174179  PubMed ID: 38646933   DOI: 10.1172/jci.insight.174179
21753  Tachibana K, Nakamura Y, Do TL, Kihara T, Kawada H, Yamamoto N, Ando K.  Mutations in the SARS-cov-2 spike proteins affected the ACE2-binding affinity during the development of omicron pandemic variants.  Biochem Biophys Res Commun  2024  719:150120  PubMed ID: 38759524   DOI: 10.1016/j.bbrc.2024.150120
21781  Kitano M, Ohnishi H, Makino A, Miyamoto T, Hayashi Y, Mizuno K, Kaba S, Kawai Y, Kojima T, Kishimoto Y, Yamamoto N, Tomonaga K, Omori K.  An infection model for SARS-CoV-2 using rat transplanted with hiPSC-airway epithelial cells.  Tissue Eng Part A  2024    PubMed ID: 38832872   DOI: 10.1089/ten.TEA.2024.0016
21812  Yu H, Kohno S, Voon DC, Hussein NH, Zhang Y, Nakayama J, Takegami Y, Takahashi C.  RECK/GPR124-driven WNT signaling in pancreatic and gastric cancer cells.  Cancer Sci  2024    PubMed ID: 38923741   DOI: 10.1111/cas.16258
21871  Sugiyama Y, Okada S, Daigaku Y, Kusumoto E, Ito T.  Strategic targeting of Cas9 nickase induces large segmental duplications.  Cell Genom  2024    PubMed ID: 39053455   DOI: 10.1016/j.xgen.2024.100610
21913  Ueno K, Kurazumi H, Suzuki R, Yanagihara M, Mizoguchi T, Harada T, Morikage N, Hamano K.  miR-709 exerts an angiogenic effect through a FGF2 upregulation induced by a GSK3B downregulation  Sci Rep  2024  14(1):11372  PubMed ID: 38762650   DOI: 10.1038/s41598-024-62340-4
21920  Sekine W, Kamiki H, Ishida H, Matsugo H, Ohira K, Li K, Katayama M, Takenaka-Uema A, Murakami S, Horimoto T.  Adaptation potential of H3N8 canine influenza virus in human respiratory cells.  Sci Rep  2024  14(1):18750  PubMed ID: 39138310   DOI: 10.1038/s41598-024-69509-x
21932  Miyahara S, Ohuchi M, Nomura M, Hashimoto E, Soga T, Saito R, Hayashi K, Sato T, Saito M, Yamashita Y, Shimada M, Yaegashi N, Yamada H, Tanuma N.  FDX2, an iron-sulfur cluster assembly factor, is essential to prevent cellular senescence, apoptosis or ferroptosis of ovarian cancer cells.  J Biol Chem  2024  107678  PubMed ID: 39151727   DOI: 10.1016/j.jbc.2024.107678
21934  Tabata K, Kobayashi S, Itakura Y, Gonzalez G, Kabamba CF, Saito S, Sasaki M, Hall WW, Sawa H, Orba Y.  Increased production of orthoflavivirus single-round infectious particles produced in mammalian cells at a suboptimal culture temperature of 28°C.  J Virol Methods  2024  115007  PubMed ID: 39154937   DOI: 10.1016/j.jviromet.2024.115007
21935  Wang Y, Moh-Moh-Aung A, Wang T, Fujisawa M, Ohara T, Yamamoto KI, Sakaguchi M, Yoshimura T, Matsukawa A.  Exosomal delivery of miR-200b-3p suppresses the growth of hepatocellular carcinoma cells by targeting ERG- and VEGF-mediated angiogenesis.  Gene  2024  148874  PubMed ID: 39159792   DOI: 10.1016/j.gene.2024.148874
21952  Chiu CT, Tsai HH, Chen JY, Hu CJ, Chen HW.  An Immunoreceptor-Targeting Strategy with Minimalistic C3b Peptide Fusion Enhances SARS-CoV-2 RBD mRNA Vaccine Immunogenicity.  Int J Nanomedicine  2024  19:7201-7214  PubMed ID: 39050877   DOI: 10.2147/IJN.S463546
21956  Ueno M, Sugiyama H, Li F, Nishimura T, Arakawa H, Chen X, Cheng X, Takeuchi S, Takeshita Y, Takamura T, Miyagi S, Toyama T, Soga T, Masuo Y, Kato Y, Nakamura H, Tsujiguchi H, Hara A, Tajima A, Noguchi-Shinohara M, Ono K, Kurayoshi K, Kobayashi M, Tadokoro Y, Kasahara A, Shoulkamy MI, Maeda K, Ogoshi T, Hirao A.  A Supramolecular Biosensor for Rapid and High-Throughput Quantification of a Disease-Associated Niacin Metabolite.  Anal Chem  2024    PubMed ID: 39183562   DOI: 10.1021/acs.analchem.4c02653
21967  Okada M, Yamasaki S, Nakazato H, Hirahara Y, Ishibashi T, Kawamura M, Shimizu K, Fujii SI.  ARID1A-Deficient Tumors Acquire Immunogenic Neoantigens during the Development of Resistance to Targeted Therapy.  Cancer Res  2024  84(17):2792-2805  PubMed ID: 39228255   DOI: 10.1158/0008-5472.CAN-23-2846
21975  Koike T, Sato T, Oe S, Hayashi S, Seki-Omura R, Nakano Y, Iwashita H, Sato Y, Hirahara Y, Kitada M.  CD34 distribution in C-fiber low threshold mechanoreceptors in the mouse dorsal root ganglion and spinal cord.  Brain Res  2024  1846:149227  PubMed ID: 39255903   DOI: 10.1016/j.brainres.2024.149227
21979  Mori S, Kohyama M, Yasumizu Y, Tada A, Tanzawa K, Shishido T, Kishida K, Jin H, Nishide M, Kawada S, Motooka D, Okuzaki D, Naito R, Nakai W, Kanda T, Murata T, Terao C, Ohmura K, Arase N, Kurosaki T, Fujimoto M, Suenaga T, Kumanogoh A, Sakaguchi S, Ogawa Y, Arase H.  Neoself-antigens are the primary target for autoreactive T cells in human lupus.  Cell  2024    PubMed ID: 39276775   DOI: 10.1016/j.cell.2024.08.025
21993  Kashiwagi M, Beck G, Kanuka M, Arai Y, Tanaka K, Tatsuzawa C, Koga Y, Saito YC, Takagi M, Oishi Y, Sakaguchi M, Baba K, Ikuno M, Yamakado H, Takahashi R, Yanagisawa M, Murayama S, Sakurai T, Sakai K, Nakagawa Y, Watanabe M, Mochizuki H, Hayashi Y.  A pontine-medullary loop crucial for REM sleep and its deficit in Parkinson's disease.  Cell  2024    PubMed ID: 39303715   DOI: 10.1016/j.cell.2024.08.046
17565  Arai Y, Yamanaka I, Okamoto T, Isobe A, Nakai N, Kamimura N, Suzuki T, Daidoji T, Ono T, Nakaya T, Matsumoto K, Okuzaki D, Watanabe Y.  Stimulation of interferon-β responses by aberrant SARS-CoV-2 small viral RNAs acting as retinoic acid-inducible gene-I agonists  iScience  2023  26(1):105742  PubMed ID: 36507221   DOI: 10.1016/j.isci.2022.105742
17804  Toshiki Takahashi, Jun Shirai, Miyo Matsuda, Sae Nakanaga, Shin Matsushita, Kei Wakita, Mizuki Hayashishita, Rigel Suzuki, Aya Noguchi, Naoto Yokota, and Hiroyuki Kawahara  Protein quality control machinery supports primary ciliogenesis by eliminating GDP-bound Rab8- family GTPases  iScience  2023      DOI: 10.1016/ j.isci.2023.106652
18094  Nakajima M, Kawahara R, Simizu S.  Cofilin promotes vasculogenic mimicry by regulating the actin cytoskeleton in human breast cancer cells  FEBS Lett  2023  597(8):1114-1124  PubMed ID: 36737242   DOI: 10.1002/1873-3468.14594
18098  Gohara Y, Tomonobu N, Kinoshita R, Futami J, Audebert L, Chen Y, Komalasari NLGY, Jiang F, Yoshizawa C, Murata H, Yamamoto KI, Watanabe M, Kumon H, Sakaguchi M.  Novel extracellular role of REIC/Dkk-3 protein in PD-L1 regulation in cancer cells  J Mol Med (Berl)   2023  101(4):431-447  PubMed ID: 36869893   DOI: 10.1007/s00109-023-02292-w
18106  Komalasari NLGY, Tomonobu N, Kinoshita R, Chen Y, Sakaguchi Y, Gohara Y, Jiang F, Yamamoto KI, Murata H, Ruma IMW, Sumardika IW, Zhou J, Yamauchi A, Kuribayashi F, Inoue Y, Toyooka S, Sakaguchi M.  Lysyl oxidase-like 4 exerts an atypical role in breast cancer progression that is dependent on the enzymatic activity that targets the cell-surface annexin A2  Front Oncol  2023  13:1142907  PubMed ID: 37091157   DOI: 10.3389/fonc.2023.1142907
18139  Hoshino N, Kanadome T, Takasugi T, Itoh M, Kaneko R, Inoue YU, Inoue T, Hirabayashi T, Watanabe M, Matsuda T, Nagai T, Tarusawa E, Yagi T.  Visualization of trans homophilic interaction of clustered protocadherin in neurons  Proc Natl Acad Sci U S A  2023  120(38):e2301003120  PubMed ID: 37695902   DOI: 10.1073/pnas.2301003120
18171  Kikuchi M, Takase S, Konuma T, Noritsugu K, Sekine S, Ikegami T, Ito A, Umehara T.  GAS41 promotes H2A.Z deposition through recognition of the N terminus of histone H3 by the YEATS domain  Proc Natl Acad Sci U S A  2023  120(43):e2304103120  PubMed ID: 37844223   DOI: 10.1073/pnas.2304103120
19540  Furukawa Y, Ishii M, Ando J, Ikeda K, Igarashi KJ, Kinoshita S, Azusawa Y, Toyota T, Honda T, Nakanishi M, Ohshima K, Masuda A, Yoshida E, Kitade M, Porteus M, Terao Y, Nakauchi H, Ando M.  iPSC-derived hypoimmunogenic tissue resident memory T cells mediate robust anti-tumor activity against cervical cancer  Cell Rep Med  2023  4(12):101327  PubMed ID: 38091985   DOI: 10.1016/j.xcrm.2023.101327
19549  Uemura K, Nobori H, Sato A, Toba S, Kusakabe S, Sasaki M, Tabata K, Matsuno K, Maeda N, Ito S, Tanaka M, Anraku Y, Kita S, Ishii M, Kanamitsu K, Orba Y, Matsuura Y, Hall WW, Sawa H, Kida H, Matsuda A, Maenaka K.  2-thiouridine is a broad-spectrum antiviral nucleoside analogue against positive-strand RNA viruses  Proc Natl Acad Sci U S A  2023  120(42):e2304139120  PubMed ID: 37831739   DOI: 10.1073/pnas.2304139120
19597  Hatanaka A, Nakada S, Matsumoto G, Satoh K, Aketa I, Watanabe A, Hirakawa T, Tsujita T, Waku T, Kobayashi A.  The transcription factor NRF1 (NFE2L1) activates aggrephagy by inducing p62 and GABARAPL1 after proteasome inhibition to maintain proteostasis  Sci Rep  2023  13(1):14405  PubMed ID: 37658135   DOI: 10.1038/s41598-023-41492-9
19624  Park G, Fukasawa K, Horie T, Masuo Y, Inaba Y, Tatsuno T, Yamada T, Tokumura K, Iwahashi S, Iezaki T, Kaneda K, Kato Y, Ishigaki Y, Mieda M, Tanaka T, Ogawa K, Ochi H, Sato S, Shi YB, Inoue H, Lee H, Hinoi E.  l-Type amino acid transporter 1 in hypothalamic neurons in mice maintains energy and bone homeostasis  JCI Insight  2023  8(7):e154925  PubMed ID: 36862514   DOI: 10.1172/jci.insight.154925
19632  ukasawa K, Lyu J, Kubo T, Tanaka Y, Suzuki A, Horie T, Tomizawa A, Osumi R, Iwahashi S, Tokumura K, Murata M, Kobayashi M, Todo T, Hirao A, Hinoi E.  MEK5-ERK5 Axis Promotes Self-renewal and Tumorigenicity of Glioma Stem Cells  Cancer Res Commun  2023  3(1):148-159  PubMed ID: 36968222   DOI: 10.1158/2767-9764.CRC-22-0243
19650  Zhang S, Tsuji H, Jin H, Kitagori K, Akizuki S, Nakashima R, Yoshifuji H, Tanaka M, Arase H, Ohmura K, Morinobu A.  Rheumatoid factor recognizes specific domains of the IgG heavy chain complexed with HLA class II molecules  Rheumatology (Oxford)  2023  62(9):3151-3155.  PubMed ID: 36645239   DOI: 10.1093/rheumatology/kead024
19789  Hagkarim NC, Hajkarim MC, Suzuki T, Fujiwara T, Winkler GS, Stewart GS, Grand RJ.  Disruption of the Mammalian Ccr4-Not Complex Contributes to Transcription-Mediated Genome Instability  Cells  2023  12(14):1868  PubMed ID: 37508532   DOI: 10.3390/cells12141868
19919  Wuputra K, Tsai MH, Kato K, Ku CC, Pan JB, Yang YH, Saito S, Wu CC, Lin YC, Cheng KH, Kuo KK, Noguchi M, Nakamura Y, Yoshioka T, Wu DC, Lin CS, Yokoyama KK.  Jdp2 is a spatiotemporal transcriptional activator of the AhR via the Nrf2 gene battery  Inflamm Regen  2023  43(1):42  PubMed ID: 37596694   DOI: 10.1186/s41232-023-00290-6
19958  Hirabayashi D, Yamamoto KI, Maruyama A, Tomonobu N, Kinoshita R, Chen Y, Komalasari NLGY, Murata H, Gohara Y, Jiang F, Zhou J, Ruma IMW, Sumardika IW, Yamauchi A, Kuribayashi F, Toyooka S, Inoue Y, Sakaguchi M.  LOXL1 and LOXL4 are novel target genes of the Zn2+-bound form of ZEB1 and play a crucial role in the acceleration of invasive events in triple-negative breast cancer cells  Front Oncol  2023  13:1142886  PubMed ID: 36910659   DOI: 10.3389/fonc.2023.1142886
19991  Mitamura R, Nakano M, Isono M, Kurosawa K, Fukami T, Nakajima M.  NEAT1_2 and DAZAP1, Paraspeckle Components, Interact with PXR to Negatively Regulate CYP3A4 Induction  Drug Metab Dispos  2023  51(10):1230-1237  PubMed ID: 37349114   DOI: 10.1124/dmd.122.001065
20922  Sasaki M, Tabata K, Kishimoto M, Itakura Y, Kobayashi H, Ariizumi T, Uemura K, Toba S, Kusakabe S, Maruyama Y, Iida S, Nakajima N, Suzuki T, Yoshida S, Nobori H, Sanaki T, Kato T, Shishido T, Hall WW, Orba Y, Sato A, Sawa H.  S-217622, a SARS-CoV-2 main protease inhibitor, decreases viral load and ameliorates COVID-19 severity in hamsters.  Sci Transl Med  2023  15(679):eabq4064  PubMed ID: 36327352   DOI: 10.1126/scitranslmed.abq4064
20993  Okamoto K, Kamikubo Y, Yamauchi K, Okamoto S, Takahashi M, Ishida Y, Koike M, Ikegaya Y, Sakurai T, Hioki H.  Specific AAV2/PHP.eB-mediated gene transduction of CA2 pyramidal cells via injection into the lateral ventricle.  Sci Rep  2023  13(1):323  PubMed ID: 36609635   DOI: 10.1038/s41598-022-27372-8
21011  Hiyamizu S, Qiu H, Vuolo L, Stevenson NL, Shak C, Heesom KJ, Hamada Y, Tsurumi Y, Chiba S, Katoh Y, Stephens DJ, Nakayama K.  Multiple interactions of the dynein-2 complex with the IFT-B complex are required for effective IFT.  J Cell Sci  2023    PubMed ID: 36632779   DOI: 10.1242/jcs.260462
21015  Shoji H, Kitao K, Miyazawa T, Nakagawa S.  Potentially reduced fusogenicity of syncytin-2 in New World monkeys.  FEBS Open Bio  2023    PubMed ID: 36647789   DOI: 10.1002/2211-5463.13555
21065  Morihiro K, Osumi H, Morita S, Hattori T, Baba M, Harada N, Ohashi R, Okamoto A.  Oncolytic Hairpin DNA Pair: Selective Cytotoxic Inducer through MicroRNA-Triggered DNA Self-Assembly.  J Am Chem Soc  2023  145(1):135-142  PubMed ID: 36538570   DOI: 10.1021/jacs.2c08974
21076  Sato M, Maishi N, Hida Y, Yanagawa-Matsuda A, Alam MT, Sakakibara-Konishi J, Nam JM, Onodera Y, Konno S, Hida K.  Angiogenic inhibitor pre-administration improves the therapeutic effects of immunotherapy.  Cancer Med  2023    PubMed ID: 36808261   DOI: 10.1002/cam4.5696
21092  Yoshimoto S, Suzuki T, Otani N, Takahashi D, Toshima K, Dohmae N, Simizu S.  Destabilization of vitelline membrane outer layer protein 1 homolog (VMO1) by C-mannosylation.  FEBS Open Bio  2023    PubMed ID: 36680395   DOI: 10.1002/2211-5463.13561
21101  Ota A, Morita H, Naganuma T, Miyamoto M, Jojima K, Nojiri K, Matsuda J, Kihara A.  Bifunctional DEGS2 has higher hydroxylase activity toward substrates with very-long-chain fatty acids in the production of phytosphingosine-ceramides.  J Biol Chem  2023  104603  PubMed ID: 36907437   DOI: 10.1016/j.jbc.2023.104603
17485  Tanikawa S, Ebisu Y, Sedlačík T, Semba S, Nonoyama T, Kurokawa T, Hirota A, Takahashi T, Yamaguchi K, Imajo M, Kato H, Nishimura T, Tanei ZI, Tsuda M, Nemoto T, Gong JP, Tanaka S.  Engineering of an electrically charged hydrogel implanted into a traumatic brain injury model for stepwise neuronal tissue reconstruction  Sci Rep  2023  13(1):2233  PubMed ID: 36788295   DOI: 10.1038/s41598-023-28870-z
21104  Kawano T, Kashiwagi M, Kanuka M, Chen CK, Yasugaki S, Hatori S, Miyazaki S, Tanaka K, Fujita H, Nakajima T, Yanagisawa M, Nakagawa Y, Hayashi Y.  ER proteostasis regulators cell-non-autonomously control sleep.  Cell Rep  2023  42(3):112267  PubMed ID: 36924492   DOI: 10.1016/j.celrep.2023.112267
21158  Tao F, Kitamura K, Hanada S, Sugimoto K, Furihata T, Kojima N.  Rapid and Stable Formation Method of Human Astrocyte Spheroid in a High Viscous Methylcellulose Medium and Its Functional Advantages.  Bioengineering (Basel)  2023  10(3)  PubMed ID: 36978740   DOI: 10.3390/bioengineering10030349
21159  Watanabe T, Narahari A, Bhardwaj E, Kuriyama K, Nishimura M, Izumi T, Fujimuro M, Ohno S.  Conserved cysteine residues in Kaposi's sarcoma herpesvirus ORF34 are necessary for viral production and viral pre-initiation complex formation.  bioRxiv  2023    PubMed ID: 36945456   DOI: 10.1101/2023.03.08.531831
21179  Noritsugu K, Suzuki T, Dodo K, Ohgane K, Ichikawa Y, Koike K, Morita S, Umehara T, Ogawa K, Sodeoka M, Dohmae N, Yoshida M, Ito A.  Lysine long-chain fatty acylation regulates the TEAD transcription factor.  Cell Rep  2023  112388  PubMed ID: 37060904   DOI: 10.1016/j.celrep.2023.112388
21219  Jojima K, Kihara A.  Metabolism of sphingadiene and characterization of the sphingadiene-producing enzyme FADS3.  Biochim Biophys Acta Mol Cell Biol Lipids  2023  1868(8):159335  PubMed ID: 37209771   DOI: 10.1016/j.bbalip.2023.159335
21222  Takahashi T, Shirai J, Matsuda M, Nakanaga S, Matsushita S, Wakita K, Hayashishita M, Suzuki R, Noguchi A, Yokota N, Kawahara H.  Protein quality control machinery supports primary ciliogenesis by eliminating GDP-bound Rab8-family GTPases.  iScience  2023  26(5):106652  PubMed ID: 37182096   DOI: 10.1016/j.isci.2023.106652
21248  Kasuga Y, Ouda R, Watanabe M, Sun X, Kimura M, Hatakeyama S, Kobayashi KS.  FBXO11 constitutes a major negative regulator of MHC class II through ubiquitin-dependent proteasomal degradation of CIITA.  Proc Natl Acad Sci U S A  2023  120(24):e2218955120  PubMed ID: 37279268   DOI: 10.1073/pnas.2218955120
21258  Nishi K, Yoshii A, Abell L, Zhou B, Frausto R, Ritterhoff J, McMillen TS, Sweet I, Wang Y, Gao C, Tian R.  Branched-chain keto acids inhibit mitochondrial pyruvate carrier and suppress gluconeogenesis in hepatocytes.  Cell Rep  2023  42(6):112641  PubMed ID: 37310861   DOI: 10.1016/j.celrep.2023.112641
21261  Hiyamizu S, Qiu H, Tsurumi Y, Hamada Y, Katoh Y, Nakayama K.  Dynein-2-driven intraciliary retrograde trafficking indirectly requires multiple interactions of IFT54 in the IFT-B complex with the dynein-2 complex.  Biol Open  2023    PubMed ID: 37309605   DOI: 10.1242/bio.059976
21265  Shimohata A, Rai D, Akagi T, Usui S, Ogiwara I, Kaneda M.  The intracellular C-terminal domain of mGluR6 contains ER retention motifs.  Mol Cell Neurosci  2023  103875  PubMed ID: 37352898   DOI: 10.1016/j.mcn.2023.103875
21270  Yamaguchi S, Kamino M, Hamamura M, Otsuguro KI.  The cytosolic N-terminal region of heterologously-expressed transmembrane channel-like protein 1 (TMC1) can be cleaved in HEK293 cells.  PLoS One  2023  18(6):e0287249  PubMed ID: 37352201   DOI: 10.1371/journal.pone.0287249
21278  Okada M, Shimizu K, Nakazato H, Yamasaki S, Fujii SI.  Detection of mutant antigen-specific T cell receptors against multiple myeloma for T cell engineering.  Mol Ther Methods Clin Dev  2023  29:541-555  PubMed ID: 37359417   DOI: 10.1016/j.omtm.2023.05.014
21285  Morishita K, Kondo J, Sakon D, Hayashibara A, Tamura I, Shimizu K, Takamatsu S, Murata K, Kamada Y, Miyoshi E.  Prohaptoglobin is a possible prognostic biomarker for colorectal cancer.  Biochem Biophys Res Commun  2023  672:72-80  PubMed ID: 37343317   DOI: 10.1016/j.bbrc.2023.06.017
21309  Tanaka Y, Morozumi A, Hirokawa N.  Nodal flow transfers polycystin to determine mouse left-right asymmetry.  Dev Cell  2023    PubMed ID: 37413993   DOI: 10.1016/j.devcel.2023.06.002
21312  Omata K, Nomura I, Hirata A, Yonezuka Y, Muto H, Kuriki R, Jimbo K, Ogasa K, Kato T.  Isolation and evaluation of erythroid progenitors in the livers of larval, froglet, and adult Xenopus tropicalis.  Biol Open  2023    PubMed ID: 37421150   DOI: 10.1242/bio.059862
21316  Matsuura-Suzuki E, Toh H, Iwasaki S.  Human-rabbit Hybrid Translation System to Explore the Function of Modified Ribosomes.  Bio Protoc  2023  13(13):e4714  PubMed ID: 37456340   DOI: 10.21769/BioProtoc.4714
21317  Tokuma H, Sakano D, Tanabe K, Tanizawa Y, Shiraki N, Kume S.  Selective proteasome degradation of C-terminally-truncated human WFS1 in pancreatic beta cells.  FEBS Open Bio  2023    PubMed ID: 37440664   DOI: 10.1002/2211-5463.13674
21326  Takahashi G, Miyaoka Y.  Large-scale single-cell cloning of genome-edited cultured human cells by On-chip SPiS.  STAR Protoc  2023  4(3):102364  PubMed ID: 37329509   DOI: 10.1016/j.xpro.2023.102364
21335  Goto M, Nishimura G, Sato H, Yamaguchi Y, Morimoto N, Hashimoto H, Takahashi N.  Pharmacological profile of upacicalcet, a novel positive allosteric modulator of calcium-sensing receptor, in vitro and in vivo.  Eur J Pharmacol  2023  175936  PubMed ID: 37541363   DOI: 10.1016/j.ejphar.2023.175936
21345  Komuro H, Shinohara S, Fukushima Y, Demachi-Okamura A, Muraoka D, Masago K, Matsui T, Sugita Y, Takahashi Y, Nishida R, Takashima C, Ohki T, Shigematsu Y, Watanabe F, Adachi K, Fukuyama T, Hamana H, Kishi H, Miura D, Tanaka Y, Onoue K, Onoguchi K, Yamashita Y, Stratford R, Clancy T, Yamaguchi R, Kuroda H, Doi K, Iwata H, Matsushita H.  Single-cell sequencing on CD8+ TILs revealed the nature of exhausted T cells recognizing neoantigen and cancer/testis antigen in non-small cell lung cancer.  J Immunother Cancer  2023  11(8)  PubMed ID: 37544663   DOI: 10.1136/jitc-2023-007180
21353  Kanadome T, Hoshino N, Nagai T, Yagi T, Matsuda T.  Visualization of trans-interactions of a protocadherin-α between processes originating from single neurons.  iScience  2023  26(7):107238  PubMed ID: 37534169   DOI: 10.1016/j.isci.2023.107238
21367  Tsuji K, Kikuchi E, Takashima Y, Shoji T, Takahashi H, Ito S, Morinaga D, Kashima M, Maeda M, Kitai H, Kikuchi J, Sakakibara-Konishi J, Konno S.  Inhibition of non-homologous end joining mitigates paclitaxel resistance resulting from mitotic slippage in non-small cell lung cancer  Cell Cycle  2023  22(17):1854-1864  PubMed ID: 37592765   DOI: 10.1080/15384101.2023.2243761
21373  Suzuki MM, Iijima K, Ogami K, Shinjo K, Murofushi Y, Xie J, Wang X, Kitano Y, Mamiya A, Kibe Y, Nishimura T, Ohka F, Saito R, Sato S, Kobayashi J, Yao R, Miyata K, Kataoka K, Suzuki HI, Kondo Y.  TUG1-mediated R-loop resolution at microsatellite loci as a prerequisite for cancer cell proliferation.  Nat Commun  2023  14(1):4521  PubMed ID: 37607907   DOI: 10.1038/s41467-023-40243-8
21382  Xu J, Hashino T, Tanaka R, Kawaguchi K, Yoshida H, Kataoka T.  The BCL-2 family protein BCL-RAMBO interacts and cooperates with GRP75 to promote its apoptosis signaling pathway.  Sci Rep  2023  13(1):14041  PubMed ID: 37640805   DOI: 10.1038/s41598-023-41196-0
21398  Kanao E, Ishida K, Mizuta R, Li Y, Imami K, Tanigawa T, Sasaki Y, Akiyoshi K, Adachi J, Otsuka K, Ishihama Y, Kubo T.  Rapid and Highly Efficient Purification of Extracellular Vesicles Enabled by a TiO2 Hybridized Spongy-like Polymer.  Anal Chem  2023    PubMed ID: 37703188   DOI: 10.1021/acs.analchem.3c03411
21416  Sogawa A, Komori R, Yanagitani K, Ohfurudono M, Tsuru A, Kadoi K, Kimata Y, Yoshida H, Kohno K.  Signal sequence-triage is activated by translocon obstruction sensed by an ER stress sensor IRE1α.  Cell Struct Funct  2023    PubMed ID: 37766570   DOI: 10.1247/csf.23072
21472  Takeuchi K, Tabe S, Takahashi K, Aoshima K, Matsuo M, Ueno Y, Furukawa Y, Yamaguchi K, Ohtsuka M, Morinaga S, Miyagi Y, Yamaguchi T, Tanimizu N, Taniguchi H.  Incorporation of human iPSC-derived stromal cells creates a pancreatic cancer organoid with heterogeneous cancer-associated fibroblasts.  Cell Rep  2023  42(11):113420  PubMed ID: 37955987   DOI: 10.1016/j.celrep.2023.113420
21501  Nishida H, Kanao E, Ishihama Y.  Centrifugal Gel Crushing Tips for Gel-Based Proteome Analysis.  Anal Chem  2023    PubMed ID: 38055789   DOI: 10.1021/acs.analchem.3c02527
21514  Nomura M, Ohuchi M, Sakamoto Y, Kudo K, Yaku K, Soga T, Sugiura Y, Morita M, Hayashi K, Miyahara S, Sato T, Yamashita Y, Ito S, Kikuchi N, Sato I, Saito R, Yaegashi N, Fukuhara T, Yamada H, Shima H, Nakayama KI, Hirao A, Kawasaki K, Arai Y, Akamatsu S, Tanuma SI, Sato T, Nakagawa T, Tanuma N.  Niacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma.  Nat Commun  2023  14(1):8095  PubMed ID: 38092728   DOI: 10.1038/s41467-023-43630-3
21660  Agata A, Ohtsuka S, Noji R, Gotoh H, Ono K, Nomura T.  A Neanderthal/Denisovan GLI3 variant contributes to anatomical variations in mice.  Front Cell Dev Biol  2023  2:11:1247361.  PubMed ID: 38020913   DOI: 10.3389/fcell.2023.1247361
21852  Mizuta H, Takakusaki A, Suzuki T, Otake K, Dohmae N, Simizu S.  C-mannosylation regulates stabilization of RAMP1 protein and RAMP1-mediated cell migration  FEBS J  2023  290(1):196-208  PubMed ID: 35942636   DOI: 10.1111/febs.16592
17502  Haraguchi-Suzuki K, Kawabata-Iwakawa R, Suzuki T, Suto T, Takazawa T, Saito S.  Local anesthetic lidocaine induces growth suppression of HeLa cells by decreasing and changing the cellular localization of the proliferation marker Ki-67  Genes Cells  2022  27(11):675-684  PubMed ID: 36074048   DOI: 10.1111/gtc.12983
17510  Miku Akishino, Yuko Aoki, Hajime Baba, Makio Asakawa, Yoichiro Hama, Susumu Mitsutake  Red algae-derived isofloridoside activates the sweet taste receptor T1R2/T1R3  Food Bioscience  2022  50:102186    DOI: 10.1016/j.fbio.2022.102186
17529  Tsukida K, Muramatsu SI, Osaka H, Yamagata T, Muramatsu K.  WDR45 variants cause ferrous iron loss due to impaired ferritinophagy associated with nuclear receptor coactivator 4 and WD repeat domain phosphoinositide interacting protein 4 reduction  Brain Commun  2022  4(6):fcac304  PubMed ID: 36751498   DOI: 10.1093/braincomms/fcac304
17581  Kamiki H, Murakami S, Nishikaze T, Hiono T, Igarashi M, Furuse Y, Matsugo H, Ishida H, Katayama M, Sekine W, Muraki Y, Takahashi M, Takenaka-Uema A, Horimoto T.  Influenza A Virus Agnostic Receptor Tropism Revealed Using a Novel Biological System with Terminal Sialic Acid Knockout Cells  J Virol  2022  96(15):e0041622  PubMed ID: 35862707   DOI: 10.1128/jvi.00416-22
17616  Yamashita F, Kaieda T, Shimomura T, Kawaguchi M, Lin CY, Johnson MD, Tanaka H, Kiwaki T, Fukushima T, Kataoka H.  Role of the polycystic kidney disease domain in matriptase chaperone activity and localization of hepatocyte growth factor activator inhibitor-1  FEBS J  2022  289(12):3422-3439  PubMed ID: 35020274   DOI: 10.1111/febs.16348
17620  Saito S, Funayama K, Kato W, Okuda M, Kawamoto M, Matsubara T, Sato T, Sato A, Otsuguro S, Sasaki M, Orba Y, Sawa H, Maenaka K, Shindo K, Imoto M, Arai MA.  Dihydromaniwamycin E, a Heat-Shock Metabolite from Thermotolerant Streptomyces sp. JA74, Exhibiting Antiviral Activity against Influenza and SARS-CoV-2 Viruses  J Nat Prod  2022  85(11):2583-2591  PubMed ID: 36223390   DOI: 10.1021/acs.jnatprod.2c00550
17651  Wei Z, Shimizu K, Sarii RS, Muthusinghe DS, Lokupathirage SMW, Nio-Kobayashi J, Yoshimatsu K.  Pathological Studies on Hantaan Virus-Infected Mice Simulating Severe Hemorrhagic Fever with Renal Syndrome  Viruses  2022  14(10):2247  PubMed ID: 36298802   DOI: 10.3390/v14102247
17675  Yamauchi K, Okamoto S, Ishida Y, Konno K, Hoshino K, Furuta T, Takahashi M, Koike M, Isa K, Watanabe M, Isa T, Hioki H.  Fluorochromized tyramide-glucose oxidase as a multiplex fluorescent tyramide signal amplification system for histochemical analysis  Sci Rep  2022  12(1):14807  PubMed ID: 36097273   DOI: 10.1038/s41598-022-19085-9
17714  Matsumura Y, To TK, Kunieda T, Kohno H, Kakutani T, Kubo T.  Mblk-1/E93, an ecdysone related-transcription factor, targets synaptic plasticity-related genes in the honey bee mushroom bodies  Sci Rep  2022  12(1):21367  PubMed ID: 36494426   DOI: 10.1038/s41598-022-23329-z
17783  Ohshima T, Yamamoto H, Sakamaki Y, Saito C, Mizushima N.  NCOA4 drives ferritin phase separation to facilitate macroferritinophagy and microferritinophagy  J Cell Biol  2022  221(10):e202203102  PubMed ID: 36066504   DOI: 10.1083/jcb.202203102
17788  Takeuchi Y, Ushimaru K, Kaneda K, Maruyama C, Ito T, Yamanaka K, Ogasawara Y, Katano H, Kato Y, Dairi T, Hamano Y.  First direct evidence for direct cell-membrane penetrations of polycationic homopoly(amino acid)s produced by bacteria  Commun Biol  2022  5(1):1132  PubMed ID: 36289442   DOI: 10.1038/s42003-022-04110-4
19238  Suzuki T, Hoshina M, Nishijima S, Hoshina N, Kikuguchi C, Tomohiro T, Fukao A, Fujiwara T, Yamamoto T.  Regulation of CCR4-NOT complex deadenylase activity and cellular responses by MK2-dependent phosphorylation of CNOT2  RNA Biol  2022  19(1):234-246  PubMed ID: 35129087   DOI: 10.1080/15476286.2021.2021676
19240  Narita M, Denk T, Matsuo Y, Sugiyama T, Kikuguchi C, Ito S, Sato N, Suzuki T, Hashimoto S, Machová I, Tesina P, Beckmann R, Inada T.  A distinct mammalian disome collision interface harbors K63-linked polyubiquitination of uS10 to trigger hRQT-mediated subunit dissociation  Nat Commun  2022  13(1):6411  PubMed ID: 36302773   DOI: 10.1038/s41467-022-34097-9
20207  Tsuji H, Ohmura K, Jin H, Naito R, Arase N, Kohyama M, Suenaga T, Sakakibara S, Kochi Y, Okada Y, Yamamoto K, Kikutani H, Morinobu A, Mimori T, Arase H.  Anti-dsDNA antibodies recognize DNA presented on HLA class II molecules of systemic lupus erythematosus risk alleles.  Arthritis Rheumatol  2022    PubMed ID: 34164946   DOI: 10.1002/art.41897
20452  Tanaka K, Kandori S, Sakka S, Nitta S, Tanuma K, Shiga M, Nagumo Y, Negoro H, Kojima T, Mathis BJ, Shimazui T, Watanabe M, Sato TA, Miyamoto T, Matsuzaka T, Shimano H, Nishiyama H.  ELOVL2 promotes cancer progression by inhibiting cell apoptosis in renal cell carcinoma.  Oncol Rep  2022  47(2)  PubMed ID: 34841437   DOI: 10.3892/or.2021.8234
20477  Arase N, Tsuji H, Takamatsu H, Jin H, Konaka H, Hamaguchi Y, Tonomura K, Kotobuki Y, Ueda-Hayakawa I, Matsuoka S, Hirano T, Yorifuji H, Murota H, Ohmura K, Nakashima R, Sato T, Kumanogoh A, Katayama I, Arase H, Fujimoto M.  Cell surface-expressed Ro52/IgG/HLA-DR complex is targeted by autoantibodies in patients with inflammatory myopathies.  J Autoimmun  2022  126:102774  PubMed ID: 34896887   DOI: 10.1016/j.jaut.2021.102774
20517  Qiu H, Tsurumi Y, Katoh Y, Nakayama K.  Combinations of deletion and missense variations of the dynein-2 DYNC2LI1 subunit found in skeletal ciliopathies cause ciliary defects.  Sci Rep  2022  12(1):31  PubMed ID: 34997029   DOI: 10.1038/s41598-021-03950-0
20522  Hiraiwa M, Fukasawa K, Iezaki T, Sabit H, Horie T, Tokumura K, Iwahashi S, Murata M, Kobayashi M, Suzuki A, Park G, Kaneda K, Todo T, Hirao A, Nakada M, Hinoi E.  SMURF2 phosphorylation at Thr249 modifies glioma stemness and tumorigenicity by regulating TGF-β receptor stability.  Commun Biol  2022  5(1):22  PubMed ID: 35017630   DOI: 10.1038/s42003-021-02950-0
20524  Nomura T, Nagao K, Shirai R, Gotoh H, Umeda M, Ono K.  Temperature sensitivity of Notch signaling underlies species-specific developmental plasticity and robustness in amniote brains.  Nat Commun  2022  13(1):96  PubMed ID: 35013223   DOI: 10.1038/s41467-021-27707-5
16114  Wuputra K, Tsai MH, Kato K, Yang YH, Pan JB, Ku CC, Noguchi M, Kishikawa S, Nakade K, Chen HL, Liu CJ, Nakamura Y, Kuo KK, Lin YC, Chan TF, Wu DC, Hou MF, Huang SK, Lin CS, Yokoyama KK.  Dimethyl sulfoxide stimulates the AhR-Jdp2 axis to control ROS accumulation in mouse embryonic fibroblasts  Cell Biol Toxicol  2022  Mar 15  PubMed ID: 33723743   DOI: 10.1007/s10565-021-09592-2
20588  Jin H, Kishida K, Arase N, Matsuoka S, Nakai W, Kohyama M, Suenaga T, Yamamoto K, Sasazuki T, Arase H.  Abrogation of self-tolerance by misfolded self-antigens complexed with MHC class II molecules.  Sci Adv  2022  8(9):eabj9867  PubMed ID: 35245125   DOI: 10.1126/sciadv.abj9867
20597  Murakami Y, Masaki M, Miyazaki S, Oketani R, Hayashi Y, Yanagisawa M, Honjoh S, Kano H.  Spectroscopic second and third harmonic generation microscopy using a femtosecond laser source in the third near-infrared (NIR-III) optical window.  Biomed Opt Express  2022  13(2):694-708  PubMed ID: 35284173   DOI: 10.1364/BOE.446273
20641  Miyajima Y, Noguchi S, Tanaka Y, Li JR, Nishimura H, Kishima M, Lim J, Furuhata E, Suzuki T, Kasukawa T, Suzuki H.  Prediction of transcription factors associated with DNA demethylation during human cellular development.  Chromosome Res  2022  30(1):109-121  PubMed ID: 35142952   DOI: 10.1007/s10577-022-09685-6
20659  Chino H, Yamasaki A, Ode KL, Ueda HR, Noda NN, Mizushima N.  Phosphorylation by casein kinase 2 enhances the interaction between ER-phagy receptor TEX264 and ATG8 proteins.  EMBO Rep  2022  e54801  PubMed ID: 35417087   DOI: 10.15252/embr.202254801
20702  Nashimoto Y, Matsushita F, Dijkstra JM, Nakamura Y, Akiyama H, Hamako J, Morita T, Araki S, Matsui T.  Bitiscetin-3, a Novel C-Type Lectin-like Protein Cloned from the Venom Gland of the Viper Bitis arietans, Induces Platelet Agglutination and Inhibits Binding of Von Willebrand Factor to Collagen.  Toxins (Basel)  2022  14(4)  PubMed ID: 35448845   DOI: 10.3390/toxins14040236
20704  Kamo H, Kawahara R, Simizu S.  Tyrosinase suppresses vasculogenic mimicry in human melanoma cells.  Oncol Lett  2022  23(5):169  PubMed ID: 35496574   DOI: 10.3892/ol.2022.13289
20713  Satoda Y, Noguchi T, Fujii T, Taniguchi A, Katoh Y, Nakayama K.  BROMI/TBC1D32 together with CCRK/CDK20 and FAM149B1/JBTS36 contributes to IFT turnaround involving ICK/CILK1.  Mol Biol Cell  2022  mbcE22030089  PubMed ID: 35609210   DOI: 10.1091/mbc.E22-03-0089
16502  Kamada H, Yasuhira S, Shibazaki M, Amano H, Maesawa C.  DUSP4 Inactivation Leads to Reduced Extracellular Signal‒Regulated Kinase Activity through Upregulation of DUSP6 in Melanoma Cells  J Invest Dermatol  2022  S0022-202X(22)00126-9  PubMed ID: 35189148   DOI: 10.1016/j.jid.2022.02.007
20729  Ishida Y, Tasaki K, Katoh Y, Nakayama K.  Molecular basis underlying the ciliary defects caused by IFT52 variations found in skeletal ciliopathies.  Mol Biol Cell  2022  mbcE22050188  PubMed ID: 35704471   DOI: 10.1091/mbc.E22-05-0188
16632  Hada M, Miura H, Tanigawa A, Matoba S, Inoue K, Ogonuki N, Hirose M, Watanabe N, Nakato R, Fujiki K, Hasegawa A, Sakashita A, Okae H, Miura K, Shikata D, Arima T, Shirahige K, Hiratani I, Ogura A.  Highly rigid H3.1/H3.2-H3K9me3 domains set a barrier for cell fate reprogramming in trophoblast stem cells  Genes Dev  2022  36(1-2):84-102  PubMed ID: 34992147   DOI: 10.1101/gad.348782.121
16658  Sasaki K, Suzuki M, Sonoda T, Schneider-Poetsch T, Ito A, Takagi M, Fujishiro S, Sohtome Y, Dodo K, Umehara T, Aburatani H, Shin-Ya K, Nakao Y, Sodeoka M, Yoshida M.  Visualization of the dynamic interaction between nucleosomal histone H3K9 tri-methylation and HP1α chromodomain in living cells  Cell Chem Biol  2022  S2451-9456(22)00198-2  PubMed ID: 35728598   DOI: 10.1016/j.chembiol.2022.05.006
16659  Matsuura-Suzuki E, Shimazu T, Takahashi M, Kotoshiba K, Suzuki T, Kashiwagi K, Sohtome Y, Akakabe M, Sodeoka M, Dohmae N, Ito T, Shinkai Y, Iwasaki S.  METTL18-mediated histidine methylation of RPL3 modulates translation elongation for proteostasis maintenance  Elife  2022  11:e72780  PubMed ID: 35674491   DOI: 10.7554/eLife.72780
20750  Yamada T, Fukasawa K, Horie T, Kadota T, Lyu J, Tokumura K, Ochiai S, Iwahashi S, Suzuki A, Park G, Ueda R, Yamamoto M, Kitao T, Shirahase H, Ochi H, Sato S, Iezaki T, Hinoi E.  The role of CDK8 in mesenchymal stem cells in controlling osteoclastogenesis and bone homeostasis.  Stem Cell Reports  2022    PubMed ID: 35777359   DOI: 10.1016/j.stemcr.2022.06.001
16732  Zhu Z, Kitano T, Morimatsu M, Tanaka A, Morioka R, Lin X, Orino K, Yoshikawa Y.  BRCA2 C-Terminal RAD51-Binding Domain Confers Resistance to DNA-Damaging Agents  Int J Mol Sci  2022  23(7):4060  PubMed ID: 35409418   DOI: 10.3390/ijms23074060
16747  Fujii K, Morita S, Mochizuki M, Shibuya-Takahashi R, Fujimori H, Yamaguchi K, Abe J, Yamazaki T, Imai T, Sugamura K, Yasuda J, Satoh K, Sato I, Saito-Koyama R, Fujishima F, Sasano H, Kato Y, Matsuura K, Asada Y, Tamai K.  Establishment of a monoclonal antibody against glycosylated CD271 specific for cancer cells in immunohistochemistry  Cancer Sci . 2022 Mar 28  2022  Mar 28  PubMed ID: 35343032   DOI: 10.1111/cas.15340
16748  Song W, Isaji T, Nakano M, Liang C, Fukuda T, Gu J.  O-GlcNAcylation regulates β1,4-GlcNAc-branched N-glycan biosynthesis via the OGT/SLC35A3/GnT-IV axis  FASEB J  2022  36(2):e22149  PubMed ID: 34981577   DOI: 10.1096/fj.202101520R
16749  Kitanishi T, Tashiro M, Kitanishi N, Mizuseki K.  Intersectional, anterograde transsynaptic targeting of neurons receiving monosynaptic inputs from two upstream regions  Commun Biol  2022  5(1):149  PubMed ID: 35190665   DOI: 10.1038/s42003-022-03096-3
16750  Otsuka K, Sawai-Ogawa M, Kihara A.  Formation of fatty alcohols-components of meibum lipids-by the fatty acyl-CoA reductase FAR2 is essential for dry eye prevention  FASEB J  2022  36(4):e22216  PubMed ID: 35238077   DOI: 10.1096/fj.202101733R
16765  Takahashi S, Shibutani S, Iwata H.  Nuclear-targeted 4E-BP1 is dephosphorylated, induces nuclear translocation of eIF4E, and alters mRNA translation  Exp Cell Res  2022  418(1):113246  PubMed ID: 35697076   DOI: 10.1016/j.yexcr.2022.113246
20788  Oishi T, Ito M, Koizumi S, Horikawa M, Yamamoto T, Yamagishi S, Yamasaki T, Sameshima T, Suzuki T, Sugimura H, Namba H, Kurozumi K.  Efficacy of HSV-TK/GCV system suicide gene therapy using SHED expressing modified HSV-TK against lung cancer brain metastases.  Mol Ther Methods Clin Dev  2022  26:253-265  PubMed ID: 35892087   DOI: 10.1016/j.omtm.2022.07.001
20822  Deai M, Oya R, Saso N, Tanaka A, Uchida I, Miyake Y, Tachihara R, Otsugu M, Mine A, Sato K, Tomura H.  Ethylenediaminetetraacetic acid (EDTA) enhances cAMP production in human TDAG8-expressing cells.  Biochem Biophys Res Commun  2022  626:15-20  PubMed ID: 35964552   DOI: 10.1016/j.bbrc.2022.07.110
17100  Izumi A, Yamamoto K, Kawaguchi M, Yamashita F, Fukushima T, Kiwaki T, Tanaka H, Yamashita Y, Kataoka H.  Insufficiency of hepatocyte growth factor activator inhibitor-1 confers lymphatic invasion of tongue carcinoma cells  Cancer Sci  2022  113(6):2179-2193  PubMed ID: 35332604   DOI: 10.1111/cas.15346
20836  Kashio M, Masubuchi S, Tominaga M.  Protein kinase C (PKC)-mediated phosphorylation of TRPM2 Thr738 counteracts the effect of cytosolic Ca2+ and elevates the temperature threshold.  J Physiol  2022    PubMed ID: 36042566   DOI: 10.1113/JP283350
20845  Zhou Z, Katoh Y, Nakayama K.  CEP19-RABL2-IFT-B axis controls BBSome-mediated ciliary GPCR export.  Mol Biol Cell  2022    PubMed ID: 36074075   DOI: 10.1091/mbc.E22-05-0161
20857  Nohara T, Ohno Y, Kihara A.  Impaired production of skin barrier lipid acylceramides and abnormal localization of PNPLA1 due to ichthyosis-causing mutations in PNPLA1.  J Dermatol Sci  2022  107(2):89-94  PubMed ID: 35970721   DOI: 10.1016/j.jdermsci.2022.07.008
20869  Lyu X, Imai S, Yamano T, Hanayama R.  Preventing SARS-CoV-2 Infection Using Anti-spike Nanobody-IFN-β Conjugated Exosomes.  Pharm Res  2022    PubMed ID: 36163411   DOI: 10.1007/s11095-022-03400-0
20873  Yamamura N, Mikkaichi T, Itokawa KI, Hoshi M, Damme K, Geigner S, Baumhauer C.  Mirogabalin, a novel α2δ ligand, is not a substrate of LAT1, but of PEPT1, PEPT2, OAT1, OAT3, OCT2, MATE1 and MATE2-K.  Xenobiotica  2022  1-42  PubMed ID: 36170033   DOI: 10.1080/00498254.2022.2129517
20880  Kanadome T, Hayashi K, Seto Y, Eiraku M, Nakajima K, Nagai T, Matsuda T.  Development of intensiometric indicators for visualizing N-cadherin interaction across cells.  Commun Biol  2022  5(1):1065  PubMed ID: 36207396   DOI: 10.1038/s42003-022-04023-2
20892  Mang D, Mayu K, Toyama T, Yamagishi T, Sato R.  BmGr4 responds to sucrose and glucose and expresses in tachykinin-related peptide-secreting enteroendocrine cells.  Insect Biochem Mol Biol  2022  103858  PubMed ID: 36244651   DOI: 10.1016/j.ibmb.2022.103858
20906  Nakazato A, Mochizuki M, Shibuya-Takahashi R, Fujimori H, Fujii K, Saijoh S, Morita S, Yamazaki T, Imai T, Sato I, Satoh K, Yamaguchi K, Sugamura K, Yasuda J, Matsuura K, Shojaku H, Asada Y, Tamai K.  RELA is required for CD271 expression and stem-like characteristics in hypopharyngeal cancer.  Sci Rep  2022  12(1):17751  PubMed ID: 36273237   DOI: 10.1038/s41598-022-22736-6
20912  Kotani N, Nakano T, Kuwahara R.  Host cell membrane proteins located near SARS-CoV-2 spike protein attachment sites are identified using proximity labeling and proteomic analysis.  J Biol Chem  2022  298(11):102500  PubMed ID: 36152751   DOI: 10.1016/j.jbc.2022.102500
20914  Wang TW, Johmura Y, Suzuki N, Omori S, Migita T, Yamaguchi K, Hatakeyama S, Yamazaki S, Shimizu E, Imoto S, Furukawa Y, Yoshimura A, Nakanishi M.  Blocking PD-L1-PD-1 improves senescence surveillance and ageing phenotypes.  Nature  2022    PubMed ID: 36323784   DOI: 10.1038/s41586-022-05388-4
20926  Akiyama M, Unoki T, Aoki H, Nishimura A, Shinkai Y, Warabi E, Nishiyama K, Furumoto Y, Anzai N, Akaike T, Nishida M, Kumagai Y.  Cystine-dependent antiporters buffer against excess intracellular reactive sulfur species-induced stress.  Redox Biol  2022  57:102514  PubMed ID: 36279630   DOI: 10.1016/j.redox.2022.102514
17337  Sekine W, Takenaka-Uema A, Kamiki H, Ishida H, Matsugo H, Murakami S, Horimoto T.  Adaptation of the H7N2 Feline Influenza Virus to Human Respiratory Cell Culture  Viruses  2022  14(5):1091  PubMed ID: 35632832   DOI: 10.3390/v14051091
20971  Tatsumi A, Hirakochi H, Inoue S, Tanaka Y, Furuno H, Ikeda M, Ishibashi S, Taguchi T, Yamamoto K, Onishi I, Sachs Z, Largaespada DA, Kitagawa M, Kurata M.  Identification of NRAS Downstream Genes with CRISPR Activation Screening.  Biology (Basel)  2022  11(11)  PubMed ID: 36358254   DOI: 10.3390/biology11111551
20975  Moriyama H, Moriyama M, Ozawa T, Tsuruta D, Hayakawa T.  Differentiation of Human Adipose-Derived Mesenchymal Stromal/Stem Cells into Insulin-Producing Cells with A Single Tet-Off Lentiviral Vector System.  Cell J  2022  24(12):705-714  PubMed ID: 36527342   DOI: 10.22074/cellj.2022.557533.1063
20998  Ozono T, Kimura Y, Suenaga T, Beck G, Jinno J, Aguirre C, Ikenaka K, Krainc D, Mochizuki H, Arase H.  Extracellular transportation of α-synuclein by HLA class II molecules.  Biochem Biophys Res Commun  2022  644:25-33  PubMed ID: 36621149   DOI: 10.1016/j.bbrc.2022.12.082
21033  Takahashi TM, Hirano A, Kanda T, Saito VM, Ashitomi H, Tanaka KZ, Yokoshiki Y, Masuda K, Yanagisawa M, Vogt KE, Tokuda T, Sakurai T.  Optogenetic induction of hibernation-like state with modified human Opsin4 in mice.  Cell Rep Methods  2022  2(11):100336  PubMed ID: 36452866   DOI: 10.1016/j.crmeth.2022.100336
21037  Takahashi M, Kobayashi T, Mizuma H, Yamauchi K, Okamoto S, Okamoto K, Ishida Y, Koike M, Watanabe M, Isa T, Hioki H.  Preferential arborization of dendrites and axons of parvalbumin- and somatostatin-positive GABAergic neurons within subregions of the mouse claustrum.  Neurosci Res  2022    PubMed ID: 36574563   DOI: 10.1016/j.neures.2022.11.008
17361  Hirose Y, Shindo N, Mori M, Onitsuka S, Isogai H, Hamada R, Hiramoto T, Ochi J, Takahashi D, Ueda T, Caaveiro JMM, Yoshida Y, Ohdo S, Matsunaga N, Toba S, Sasaki M, Orba Y, Sawa H, Sato A, Kawanishi E, Ojida A.  Discovery of Chlorofluoroacetamide-Based Covalent Inhibitors for Severe Acute Respiratory Syndrome Coronavirus 2 3CL Protease  J Med Chem  2022  65(20):13852-13865  PubMed ID: 36229406   DOI: 10.1021/acs.jmedchem.2c01081
21141  Suenaga T, Mori Y, Suzutani T, Arase H.  Siglec-7 mediates varicella-zoster virus infection by associating with glycoprotein B.  Biochem Biophys Res Commun  2022  607:67-72  PubMed ID: 35367830   DOI: 10.1016/j.bbrc.2022.03.060
17694  Furuta T, Yamauchi K, Okamoto S, Takahashi M, Kakuta S, Ishida Y, Takenaka A, Yoshida A, Uchiyama Y, Koike M, Isa K, Isa T, Hioki H.  Multi-scale light microscopy/electron microscopy neuronal imaging from brain to synapse with a tissue clearing method, Sca l eSF  iScience  2021  25(1):103601  PubMed ID: 35106459   DOI: 10.1016/j.isci.2021.103601
12798  Johmura Y, Yamanaka T, Omori S, Wang TW, Sugiura Y, Matsumoto M, Suzuki N, Kumamoto S, Yamaguchi K, Hatakeyama S, Takami T, Yamaguchi R, Shimizu E, Ikeda K, Okahashi N, Mikawa R, Suematsu M, Arita M, Sugimoto M, Nakayama KI, Furukawa Y, Imoto S, Nakanishi M.  Senolysis by glutaminolysis inhibition ameliorates various age-associated disorders  Science  2021  371(6526):265-270  PubMed ID: 33446552   DOI: 10.1126/science.abb5916
13320  Matsumoto N, Sekiya M, Fujimoto Y, Haga S, Sun-Wada GH, Wada Y, Nakanishi-Matsui M.  Functional complementation of V-ATPase a subunit isoforms in osteoclasts.  J Biochem  2021  169(4):459-466  PubMed ID: 33135054   DOI: 10.1093/jb/mvaa118
13345  Daifu T, Mikami M, Hiramatsu H, Iwai A, Umeda K, Noura M, Kubota H, Masuda T, Furuichi K, Takasaki S, Noguchi Y, Morita K, Bando T, Hirata M, Kataoka TR, Nakahata T, Kuwahara Y, Iehara T, Hosoi H, Takita J, Sugiyama H, Adachi S, Kamikubo Y.  Suppression of malignant rhabdoid tumors through Chb-M'-mediated RUNX1 inhibition.  Pediatr Blood Cancer  2021    PubMed ID: 33180377   DOI: 10.1002/pbc.28789
13351  Matsumoto Y, Kishida K, Matsumoto M, Matsuoka S, Kohyama M, Suenaga T, Arase H.  A TCR-like antibody against a proinsulin-containing fusion peptide ameliorates type 1 diabetes in NOD mice.  Biochem Biophys Res Commun  2021    PubMed ID: 33208230   DOI: 10.1016/j.bbrc.2020.11.019
13463  Shota Someya et al  Tryptophan Metabolism Regulates Proliferative Capacity of Human Pluripotent Stem Cells  iScienc  2021  24  PubMed ID: 33615198   DOI: 10.1016/j.isci.2021.102090
20008  Umaba R, Kitanishi T, Mizuseki K.  Monosynaptic connection from the subiculum to medial mammillary nucleus neurons projecting to the anterior thalamus and Gudden's ventral tegmental nucleus.  Neurosci Res  2021    PubMed ID: 33476683   DOI: 10.1016/j.neures.2021.01.006
20053  Takafuji S, Mori T, Nishimura N, Yamamoto N, Uemura S, Nozu K, Terui K, Toki T, Ito E, Muramatsu H, Takahashi Y, Matsuo M, Yamamura T, Iijima K.  Usefulness of functional splicing analysis to confirm precise disease pathogenesis in Diamond-Blackfan anemia caused by intronic variants in RPS19.  Pediatr Hematol Oncol  2021  1-16  PubMed ID: 33622161   DOI: 10.1080/08880018.2021.1887984
20060  Nishiike Y, Miyazoe D, Togawa R, Yokoyama K, Nakasone K, Miyata M, Kikuchi Y, Kamei Y, Todo T, Ishikawa-Fujiwara T, Ohno K, Usami T, Nagahama Y, Okubo K.  Estrogen receptor 2b is the major determinant of sex-typical mating behavior and sexual preference in medaka.  Curr Biol  2021    PubMed ID: 33639108   DOI: 10.1016/j.cub.2021.01.089
13513  Takahashi Y, Wake H, Sakaguchi M, Yoshii Y, Teshigawara K, Wang D, Nishibori M.  Histidine-Rich Glycoprotein Stimulates Human Neutrophil Phagocytosis and Prolongs Survival through CLEC1A  J Immunol   2021  206(4):737-750  PubMed ID: 33452125   DOI: 10.4049/jimmunol.2000817
20067  Aizawa N, Fujimori Y, Nakanishi O, Hayashi T, Goi Y, Kobayashi JI, Fujita T.  Efficacy of the combination of KPR-5714, a novel transient receptor potential melastatin 8 (TRPM8) antagonist, and β3-adrenoceptor agonist or anticholinergic agent on bladder dysfunction in rats with bladder overactivity.  Eur J Pharmacol  2021  173995  PubMed ID: 33675781   DOI: 10.1016/j.ejphar.2021.173995
20068  Nakamura R, Oyama T, Inokuchi M, Ishikawa S, Hirata M, Kawashima H, Ikeda H, Dobashi Y, Ooi A.  Neural EGFL like 2 expressed in myoepithelial cells and suppressed breast cancer cell migration.  Pathol Int  2021    PubMed ID: 33657249   DOI: 10.1111/pin.13087
13640  Fujita K, Koide N, Somiya M, Kuroda S, Hinuma S.  A regulatory role of scavenger receptor class B type 1 in endocytosis and lipid droplet formation induced by liposomes containing phosphatidylethanolamine in HEK293T cells  Biochim Biophys Acta Mol Cell Res  2021  1868(1):118859  PubMed ID: 32956759   DOI: 10.1016/j.bbamcr.2020.118859
20083  Hama K, Fujiwara Y, Hayama T, Ozawa T, Nozawa K, Matsuda K, Hashiguchi Y, Yokoyama K.  Very long-chain fatty acids are accumulated in triacylglycerol and nonesterified forms in colorectal cancer tissues.  Sci Rep  2021  11(1):6163  PubMed ID: 33731797   DOI: 10.1038/s41598-021-85603-w
20103  McKee HK, Kajiwara C, Yamaguchi T, Ishii Y, Shimizu N, Ohara A, Tateda K.  Clostridioides difficile toxins enhanced the in vitro production of CXC chemokine ligand 2 and tumor necrosis factor-α via Toll-like receptors in macrophages.  J Med Microbiol  2021  70(4)  PubMed ID: 33830910   DOI: 10.1099/jmm.0.001342
13898  Takuma Kitanishi, Ryoko Umaba, Kenji Mizuseki  Robust information routing by dorsal subiculum neurons  Sci Adv  2021  7(11):eabf1913  PubMed ID: 33692111   DOI: 10.1126/sciadv.abf1913
13913  Rai D, Akagi T, Shimohata A, Ishii T, Gangi M, Maruyama T, Wada-Kiyama Y, Ogiwara I, Kaneda M.  Involvement of the C-terminal domain in cell surface localization and G-protein coupling of mGluR6  J Neurochem  2021  158(4):837-848  PubMed ID: 33067823   DOI: 10.1111/jnc.15217
20114  Ojiro I, Nishio H, Yamazaki-Ito T, Nakano S, Ito S, Toyohara Y, Hiramoto T, Terada Y, Ito K.  Trp-Trp acts as a multi-functional blocker for human bitter taste receptors, hTAS2R14, hTAS2R16, hTAS2R43, and hTAS2R46.  Biosci Biotechnol Biochem  2021    PubMed ID: 33844825   DOI: 10.1093/bbb/zbab061
20138  Nagumo Y, Kandori S, Tanuma K, Nitta S, Chihara I, Shiga M, Hoshi A, Negoro H, Kojima T, Mathis BJ, Funakoshi Y, Nishiyama H.  PLD1 promotes tumor invasion by regulation of MMP-13 expression via NF-κB signaling in bladder cancer.  Cancer Lett  2021  511:15-25  PubMed ID: 33945837   DOI: 10.1016/j.canlet.2021.04.014
20147  Kariya Y, Oyama M, Suzuki T, Kariya Y.  αvβ3 Integrin induces partial EMT independent of TGF-β signaling.  Commun Biol  2021  4(1):490  PubMed ID: 33883697   DOI: 10.1038/s42003-021-02003-6
14182  Somiya M, Kuroda S.  Real-Time Luminescence Assay for Cytoplasmic Cargo Delivery of Extracellular Vesicles  Anal Chem  2021  93(13):5612-5620  PubMed ID: 33759512   DOI: 10.1021/acs.analchem.1c00339
20150  Takeshita M, Suzuki K, Nakazawa M, Kamata H, Ishii M, Oyamada Y, Oshima H, Takeuchi T.  Antigen-driven autoantibody production in lungs of interstitial lung disease with autoimmune disease.  J Autoimmun  2021  121:102661  PubMed ID: 34034155   DOI: 10.1016/j.jaut.2021.102661
20155  Sahoo PR, Kowada T, Mizukami S.  Long-Term Mg2+ Imaging in Live Cells with a Targetable Fluorescent Probe.  Methods Mol Biol  2021  2274:237-243  PubMed ID: 34050476   DOI: 10.1007/978-1-0716-1258-3_20
20157  Matsui H, Ito J, Matsui N, Uechi T, Onodera O, Kakita A.  Cytosolic dsDNA of mitochondrial origin induces cytotoxicity and neurodegeneration in cellular and zebrafish models of Parkinson's disease.  Nat Commun  2021  12(1):3101  PubMed ID: 34035300   DOI: 10.1038/s41467-021-23452-x
20158  Osakabe K, Wada N, Murakami E, Miyashita N, Osakabe Y.  Genome editing in mammalian cells using the CRISPR type I-D nuclease.  Nucleic Acids Res  2021    PubMed ID: 34076237   DOI: 10.1093/nar/gkab348
20165  Kobayashi JI, Hirasawa H, Fujimori Y, Nakanishi O, Kamada N, Ikeda T, Yamamoto A, Kanbe H.  Identification of N-acyl-N-indanyl-α-phenylglycinamides as selective TRPM8 antagonists designed to mitigate the risk of adverse effects.  Bioorg Med Chem  2021  30:115903  PubMed ID: 33333445   DOI: 10.1016/j.bmc.2020.115903
14478  Yamanaka D, Shoda M, Matsubara T, Ishibashi KI, Motoi A, Motoi R, Motoi M, Ohno N, Adachi Y.  Open-Label Study of the Influence of Food Containing the Royal Sun Mushroom, Agaricus brasiliensis KA21 (Agaricomycetes), on β-Glucan-Specific Antibody Production in Healthy Human Volunteers  Int J Med Mushrooms  2021  23(2):13-28  PubMed ID: 33639078   DOI: 10.1615/IntJMedMushrooms.2020037471
20199  Tomita T, Kato M, Mishima T, Matsunaga Y, Sanjo H, Ito KI, Minagawa K, Matsui T, Oikawa H, Takahashi S, Takao T, Iwai N, Mino T, Takeuchi O, Maru Y, Hiratsuka S.  Extracellular mRNA transported to the nucleus exerts translation-independent function.  Nat Commun  2021  12(1):3655  PubMed ID: 34135341   DOI: 10.1038/s41467-021-23969-1
20200  Kuwabara S, Tanimoto Y, Okutani M, Jie M, Haseda Y, Kinugasa-Katayama Y, Aoshi T.  Microfluidics sorting enables the isolation of an intact cellular pair complex of CD8+ T cells and antigen-presenting cells in a cognate antigen recognition-dependent manner.  PLoS One  2021  16(6):e0252666  PubMed ID: 34125844   DOI: 10.1371/journal.pone.0252666
20216  Niinae T, Imami K, Sugiyama N, Ishihama Y.  Identification of Endogenous Kinase Substrates by Proximity Labeling Combined with Kinase Perturbation and Phosphorylation Motifs.  Mol Cell Proteomics  2021  100119  PubMed ID: 34186244   DOI: 10.1016/j.mcpro.2021.100119
14782  Uemura K, Sasaki M, Sanaki T, Toba S, Takahashi Y, Orba Y, Hall WW, Maenaka K, Sawa H, Sato A.  MRC5 cells engineered to express ACE2 serve as a model system for the discovery of antivirals targeting SARS-CoV-2  Sci Rep  2021  11(1):5376  PubMed ID: 33686154   DOI: 10.1038/s41598-021-84882-7
14827  iu Y, Soh WT, Kishikawa JI, Hirose M, Nakayama EE, Li S, Sasai M, Suzuki T, Tada A, Arakawa A, Matsuoka S, Akamatsu K, Matsuda M, Ono C, Torii S, Kishida K, Jin H, Nakai W, Arase N, Nakagawa A, Matsumoto M, Nakazaki Y, Shindo Y, Kohyama M, Tomii K, Ohmura K, Ohshima S, Okamoto T, Yamamoto M, Nakagami H, Matsuura Y, Nakagawa A, Kato T, Okada M, Standley DM, Shioda T, Arase H.  An infectivity-enhancing site on the SARS-CoV-2 spike protein targeted by antibodies  Cell   2021  184(13):3452-3466.e18  PubMed ID: 34139176   DOI: 10.1016/j.cell.2021.05.032
20233  Koshizuka T, Kondo H, Kato H, Takahashi K.  Human cytomegalovirus UL42 protein inhibits the degradation of glycoprotein B through inhibition of Nedd4 family ubiquitin E3 ligases.  Microbiol Immunol  2021    PubMed ID: 34260096   DOI: 10.1111/1348-0421.12932
20240  Kaku T, Sugiura K, Entani T, Osabe K, Nagai T.  Enhanced brightness of bacterial luciferase by bioluminescence resonance energy transfer.  Sci Rep  2021  11(1):14994  PubMed ID: 34294849   DOI: 10.1038/s41598-021-94551-4
14939  Shuji Hinuma, Kazuyo Fujita, Shun’ichi Kuroda  Binding of Nanoparticles Harboring Recombinant Large Surface Protein of Hepatitis B Virus to Scavenger Receptor Class B Type 1  Viruses  2021  13:1334  PubMed ID: 34372540   DOI: 10.3390/v13071334
20244  Yoshioka K, Obara K, Oikawa S, Uemura K, Yamaguchi A, Fujisawa K, Hanazawa H, Fujiwara M, Endoh T, Suzuki T, Regadera MD, Ito D, Ou G, Xu K, Tanaka Y.  Docosahexaenoic acid inhibits U46619- and prostaglandin F2α-induced pig coronary and basilar artery contractions by inhibiting prostanoid TP receptors.  Eur J Pharmacol  2021  174371  PubMed ID: 34329614   DOI: 10.1016/j.ejphar.2021.174371
20272  Ma Y, Yoshida T, Matoba K, Kida K, Shintani R, Piao Y, Jin J, Nishino T, Hanayama R.  Identification of small compounds regulating the secretion of extracellular vesicles via a TIM4-affinity ELISA.  Sci Rep  2021  11(1):13471  PubMed ID: 34188113   DOI: 10.1038/s41598-021-92860-2
15168  Hangai S, Kawamura T, Kimura Y, Chang CY, Hibino S, Yamamoto D, Nakai Y, Tateishi R, Oshima M, Oshima H, Kodama T, Moriya K, Koike K, Yanai H, Taniguchi T.  Orchestration of myeloid-derived suppressor cells in the tumor microenvironment by ubiquitous cellular protein TCTP released by tumor cells  Nat Immunol  2021  22(8):947-957  PubMed ID: 34239121   DOI: 10.1038/s41590-021-00967-5
20282  Nakanishi E, Uemura N, Akiyama H, Kinoshita M, Masanori S, Taruno Y, Yamakado H, Matsuzawa SI, Takeda S, Hirabayashi Y, Takahashi R.  Impact of Gba2 on neuronopathic Gaucher's disease and α-synuclein accumulation in medaka (Oryzias latipes).  Mol Brain  2021  14(1):80  PubMed ID: 33971917   DOI: 10.1186/s13041-021-00790-x
20283  Sakoguchi A, Saito F, Hirayasu K, Shida K, Matsuoka S, Itagaki S, Nakai W, Kohyama M, Suenaga T, Iwanaga S, Horii T, Arase H.  Plasmodium falciparum RIFIN is a novel ligand for inhibitory immune receptor LILRB2.  Biochem Biophys Res Commun  2021  548:167-173  PubMed ID: 33647792   DOI: 10.1016/j.bbrc.2021.02.033
20298  Nagano C, Takaoka Y, Kamei K, Hamada R, Ichikawa D, Tanaka K, Aoto Y, Ishiko S, Rossanti R, Sakakibara N, Okada E, Horinouchi T, Yamamura T, Tsuji Y, Noguchi Y, Ishimori S, Nagase H, Ninchoji T, Iijima K, Nozu K.  Genotype-Phenotype Correlation in WT1 Exon 8 to 9 Missense Variants.  Kidney Int Rep  2021  6(8):2114-2121  PubMed ID: 34386660   DOI: 10.1016/j.ekir.2021.05.009
20322  Fujisawa S, Qiu H, Nozaki S, Chiba S, Katoh Y, Nakayama K.  ARL3 and ARL13B GTPases participate in distinct steps of INPP5E targeting to the ciliary membrane.  Biol Open  2021    PubMed ID: 34447983   DOI: 10.1242/bio.058843
15284  Yoshiko Iizuka, Kinuko Inomata, Risako Nohara, Akimitsu Miyawaki and Yoshifumi Watanabe  Activation of intracellular antioxidant master gene Nrf2 by the extracts of Garcinia subelliptica, Ocimum gratissimum L., and Plectranthus ornatus  International Journal of Herbal Medicine  2021  9(3):54-60   
15524  Fukasawa K, Kadota T, Horie T, Tokumura K, Terada R, Kitaguchi Y, Park G, Ochiai S, Iwahashi S, Okayama Y, Hiraiwa M, Yamada T, Iezaki T, Kaneda K, Yamamoto M, Kitao T, Shirahase H, Hazawa M, Wong RW, Todo T, Hirao A, Hinoi E.  CDK8 maintains stemness and tumorigenicity of glioma stem cells by regulating the c-MYC pathway  Oncogene  2021  40(15):2803-2815  PubMed ID: 33727660   DOI: 10.1038/s41388-021-01745-1
20354  Noguchi T, Nakamura K, Satoda Y, Katoh Y, Nakayama K.  CCRK/CDK20 regulates ciliary retrograde protein trafficking via interacting with BROMI/TBC1D32.  PLoS One  2021  16(10):e0258497  PubMed ID: 34624068   DOI: 10.1371/journal.pone.0258497
20356  Yasumura M, Hagiwara A, Hida Y, Ohtsuka T.  Planar cell polarity protein Vangl2 and its interacting protein Ap2m1 regulate dendritic branching in cortical neurons.  Genes Cells  2021    PubMed ID: 34626136   DOI: 10.1111/gtc.12899
20367  Kariya Y, Oyama M, Kariya Y, Hashimoto Y.  Phosphorylated Osteopontin Secreted from Cancer Cells Induces Cancer Cell Motility.  Biomolecules  2021  11(9)  PubMed ID: 34572536   DOI: 10.3390/biom11091323
20403  Yaguchi A, Oshikawa M, Watanabe G, Hiramatsu H, Uchida N, Hara C, Kaneko N, Sawamoto K, Muraoka T, Ajioka I.  Efficient protein incorporation and release by a jigsaw-shaped self-assembling peptide hydrogel for injured brain regeneration.  Nat Commun  2021  12(1):6623  PubMed ID: 34799548   DOI: 10.1038/s41467-021-26896-3
20440  Kanadome T, Hoshino N, Nagai T, Matsuda T, Yagi T.  Development of FRET-based indicators for visualizing homophilic trans interaction of a clustered protocadherin.  Sci Rep  2021  11(1):22237  PubMed ID: 34782670   DOI: 10.1038/s41598-021-01481-2
15879  Uemura K, Nobori H, Sato A, Sanaki T, Toba S, Sasaki M, Murai A, Saito-Tarashima N, Minakawa N, Orba Y, Kariwa H, Hall WW, Sawa H, Matsuda A, Maenaka K.  5-Hydroxymethyltubercidin exhibits potent antiviral activity against flaviviruses and coronaviruses, including SARS-CoV-2  iScience  2021  24(10):103120  PubMed ID: 34541466   DOI: 10.1016/j.isci.2021.103120
15898  Yafei Liu, Noriko Arase, Jun-ichi Kishikawa, Mika Hirose, Songling Li, Asa Tada, Sumiko Matsuoka, Akemi Arakawa, Kanako Akamatsu, Chikako Ono, Hui Jin, Kazuki Kishida, Wataru Nakai, Masako Kohyama, Atsushi Nakagawa, Yoshiaki Yamagishi, Hironori Nakagami, Atsushi Kumanogoh, Yoshiharu Matsuura, Daron M. Standley, Takayuki Kato, Masato Okada, Manabu Fujimoto, Hisashi Arase  The SARS-CoV-2 Delta variant is poised to acquire complete resistance to wild-type spike vaccines  bioRxiv  2021      DOI: 10.1101/2021.08.22.457114
20490  Ito F, Kato K, Yanatori I, Murohara T, Toyokuni S.  Ferroptosis-dependent extracellular vesicles from macrophage contribute to asbestos-induced mesothelial carcinogenesis through loading ferritin.  Redox Biol  2021  47:102174  PubMed ID: 34700146   DOI: 10.1016/j.redox.2021.102174
20493  Ishida H, Murakami S, Kamiki H, Matsugo H, Katayama M, Sekine W, Ohira K, Takenaka-Uema A, Horimoto T.  Construction of an Influenza D Virus with an Eight-Segmented Genome.  Viruses  2021  13(11)  PubMed ID: 34834971   DOI: 10.3390/v13112166
16115  Masuo K, Chen R, Yogo A, Sugiyama A, Fukuda A, Masui T, Uemoto S, Seno H, Takaishi S.  SNAIL2 contributes to tumorigenicity and chemotherapy resistance in pancreatic cancer by regulating IGFBP2  Cancer Sci  2021  112(12):4987-4999  PubMed ID: 34628696   DOI: 10.1111/cas.15162
16241  Somiya M, Kuroda S.  Reporter gene assay for membrane fusion of extracellular vesicles  J Extracell Vesicles  2021  10(13):e12171  PubMed ID: 34807503   DOI: 10.1002/jev2.12171
16324  Sheng J, Kohno S, Okada N, Okahashi N, Teranishi K, Matsuda F, Shimizu H, Linn P, Nagatani N, Yamamura M, Harada K, Horike SI, Inoue H, Yano S, Kumar S, Kitajima S, Ajioka I, Takahashi C.  Treatment of Retinoblastoma 1-Intact Hepatocellular Carcinoma With Cyclin-Dependent Kinase 4/6 Inhibitor Combination Therapy  Hepatology  2021  74(4):1971-1993  PubMed ID: 33931882   DOI: 10.1002/hep.31872
16704  PACAP-PAC1 Signaling Regulates Serotonin 2A Receptor Internalization  PACAP-PAC1 Signaling Regulates Serotonin 2A Receptor Internalization  Front Endocrinol (Lausanne)  2021  12:73245  PubMed ID: 34759890   DOI: 10.3389/fendo.2021.732456
16752  Ishii M, Ando J, Yamazaki S, Toyota T, Ohara K, Furukawa Y, Suehara Y, Nakanishi M, Nakashima K, Ohshima K, Nakauchi H, Ando M.  iPSC-Derived Neoantigen-Specific CTL Therapy for Ewing Sarcoma  Cancer Immunol Res  2021  9(10):1175-1186  PubMed ID: 34385178   DOI: 10.1158/2326-6066.CIR-21-0193
16759  Oda K, Matoba Y, Sugiyama M, Sakaguchi T.  Structural Insight into the Interaction of Sendai Virus C Protein with Alix To Stimulate Viral Budding  J Virol  2021  95(19):e0081521  PubMed ID: 34287046   DOI: 10.1128/JVI.00815-21
16762  Wang W, Zhu Y, Sun Z, Jin C, Wang X.  Positive feedback regulation between USP15 and ERK2 inhibits osteoarthritis progression through TGF-β/SMAD2 signaling  Arthritis Res Ther  2021  23(1):84  PubMed ID: 33726807   DOI: 10.1186/s13075-021-02456-4
16764  Pham Tuan Huy   Nguyen Pham Quynh Anh   Tong Thi Hang   Nguyen Hoang Khue Tu   Le Minh Thong   Nguyen Van Thuan   Yen Thi Hai Tran    Home-made in vitro magnetic nanoparticle-based gene delivery system  Science & Technology Development Journal  2021  24:2058-2065    DOI: 10.32508/stdj.v24i3.2573
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17826  Matsubara D, Yoshimoto T, Soda M, Amano Y, Kihara A, Funaki T, Ito T, Sakuma Y, Shibano T, Endo S, Hagiwara K, Ishikawa S, Fukayama M, Murakami Y, Mano H, Niki T.  Reciprocal expression of trefoil factor-1 and thyroid transcription factor-1 in lung adenocarcinomas  Cancer Sci  2020  111(6):2183-2195  PubMed ID: 32237253   DOI: 10.1111/cas.14403
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13020  Koshizuka T, Inoue N.  Activation of c-Jun by human cytomegalovirus UL42 through JNK activation.  PLoS One  2020    PubMed ID: 32369499   DOI: 10.1371/journal.pone.0232635
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13028  Kido K, Yamanaka S, Nakano S, Motani K, Shinohara S, Nozawa A, Kosako H, Ito S, Sawasaki T.  AirID, a novel proximity biotinylation enzyme, for analysis of protein-protein interactions.  Elife  2020    PubMed ID: 32391793   DOI: 10.7554/eLife.54983
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13044  Park M, Miyoshi C, Fujiyama T, Kakizaki M, Ikkyu A, Honda T, Choi J, Asano F, Mizuno S, Takahashi S, Yanagisawa M, Funato H.  Loss of the conserved PKA sites of SIK1 and SIK2 increases sleep need.  Sci Rep  2020    PubMed ID: 32457359   DOI: 10.1038/s41598-020-65647-0
13074  Horinouchi T, Yamamura T, Minamikawa S, Nagano C, Sakakibara N, Nakanishi K, Shima Y, Morisada N, Ishiko S, Aoto Y, Nagase H, Takeda H, Rossanti R, Ishimori S, Kaito H, Matsuo M, Iijima K, Nozu K.  Pathogenic evaluation of synonymous COL4A5 variants in X-linked Alport syndrome using a minigene assay.  Mol Genet Genomic Med  2020    PubMed ID: 32543079   DOI: 10.1002/mgg3.1342
13080  Ito F, Yanatori I, Maeda Y, Nimura K, Ito S, Hirayama T, Nagasawa H, Kohyama N, Okazaki Y, Akatsuka S, Toyokuni S.  Asbestos conceives Fe(II)-dependent mutagenic stromal milieu through ceaseless macrophage ferroptosis and β-catenin induction in mesothelium.  Redox Biol  2020    PubMed ID: 32863225   DOI: 10.1016/j.redox.2020.101616
13164  Yamashita J, Takeuchi A, Hosono K, Fleming T, Nagahama Y, Okubo K.  Male-predominant galanin mediates androgen-dependent aggressive chases in medaka.  Elife  2020    PubMed ID: 32783809   DOI: 10.7554/eLife.59470
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13200  Ago Y, Otsuka H, Sasai H, Abdelkreem E, Nakama M, Aoyama Y, Matsumoto H, Fujiki R, Ohara O, Akiyama K, Fukui K, Watanabe Y, Nakajima Y, Ohnishi H, Ito T, Fukao T.  Japanese patients with mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase deficiency: In vitro functional analysis of five novel HMGCS2 mutations.  Exp Ther Med  2020    PubMed ID: 32952630   DOI: 10.3892/etm.2020.9166
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13212  Kitao T, Taguchi K, Seto S, Arasaki K, Ando H, Nagai H, Kubori T.  Legionella Manipulates Non-canonical SNARE Pairing Using a Bacterial Deubiquitinase.  Cell Rep  2020    PubMed ID: 32905772   DOI: 10.1016/j.celrep.2020.108107
13276  Arai Y, Kawashita N, Elgendy EM, Ibrahim MS, Daidoji T, Ono T, Takagi T, Nakaya T, Matsumoto K, Watanabe Y.  PA Mutations Inherited during Viral Evolution Act Cooperatively To Increase Replication of Contemporary H5N1 Influenza Virus with an Expanded Host Range.  J Virol  2020    PubMed ID: 33028722   DOI: 10.1128/JVI.01582-20
13293  Okamura M, Shizu R, Abe T, Kodama S, Hosaka T, Sasaki T, Yoshinari K.  PXR Functionally Interacts with NF-κB and AP-1 to Downregulate the Inflammation-Induced Expression of Chemokine CXCL2 in Mice.  Cells  2020    PubMed ID: 33076328   DOI: 10.3390/cells9102296
13321  Kato M, Onoyama I, Kawakami M, Yoshida S, Kawamura K, Kodama K, Hori E, Cui L, Matsumura Y, Yagi H, Asanoma K, Yahata H, Itakura A, Takeda S, Kato K.  Downregulation of 5-hydroxymethylcytosine is associated with the progression of cervical intraepithelial neoplasia.  PLoS One  2020    PubMed ID: 33141854   DOI: 10.1371/journal.pone.0241482
13327  Yamazaki T, Takahashi C, Taniguchi Y, Narukawa M, Misaka T, Ano Y.  Bitter taste receptor activation by hop-derived bitter components induces gastrointestinal hormone production in enteroendocrine cells.  Biochem Biophys Res Commun  2020    PubMed ID: 33160623   DOI: 10.1016/j.bbrc.2020.10.099
13330  Osakabe K, Wada N, Miyaji T, Murakami E, Marui K, Ueta R, Hashimoto R, Abe-Hara C, Kong B, Yano K, Osakabe Y.  Genome editing in plants using CRISPR type I-D nuclease.  Commun Biol  2020  3(1):648  PubMed ID: 33159140   DOI: 10.1038/s42003-020-01366-6
13490  Shoji S, Hanada K, Takahashi M, Watanabe K, Yonemochi M, Tomabechi Y, Shirouzu M.  The NF-κB regulator IκBβ exhibits different molecular interactivity and phosphorylation status from IκBα in an IKK2-catalysed reaction  FEBS Lett  2020  594(10):1532-1549  PubMed ID: 32017069   DOI: 10.1002/1873-3468.13752
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13567  Harada M, Nghia VT, Nakao A, Tanigaki R, Fukuoka N, Nishida A, Kataoka T.  Eomesodermin promotes interaction of RelA and NFATc2 with the Ifng promoter and multiple conserved noncoding sequences across the Ifng locus in mouse lymphoma BW5147 cells  Immunol Lett  2020  225:33-43  PubMed ID: 32554052   DOI: 10.1016/j.imlet.2020.06.008
13570  Suzuki T, Morimoto N, Akaike A, Osakada F.  Multiplex Neural Circuit Tracing With G-Deleted Rabies Viral Vectors  Front Neural Circuits  2020  13:77  PubMed ID: 31998081   DOI: 10.3389/fncir.2019.00077
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13577  Shimada K, Kobayashi N, Oka N, Takahashi M, Kondo K.  Cooperative activation of the human herpesvirus 6B U79/80 early gene promoter by immediate-early proteins IE1B and IE2B  Microbiol Immunol  2020  64(11):747-761  PubMed ID: 32910457   DOI: 10.1111/1348-0421.12844
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11490  Chen Y, Sumardika IW, Tomonobu N, Winarsa Ruma IM, Kinoshita R, Kondo E, Inoue Y, Sato H, Yamauchi A, Murata H, Yamamoto KI, Tomida S, Shien K, Yamamoto H, Soh J, Liu M, Futami J, Sasai K, Katayama H, Kubo M, Putranto EW, Hibino T, Sun B, Nishibori M, Toyooka S, Sakaguchi M.  Melanoma cell adhesion molecule is the driving force behind the dissemination of melanoma upon S100A8/A9 binding in the original skin lesion.  Cancer Lett.  2019    PubMed ID: 30904617   DOI: 10.1016/j.canlet.2019.03.023
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11500  Mizuta H, Kuga K, Suzuki T, Niwa Y, Dohmae N, Simizu S.  C‑mannosylation of R‑spondin2 activates Wnt/β‑catenin signaling and migration activity in human tumor cells.  Int. J. Oncol.  2019    PubMed ID: 30942431   DOI: 10.3892/ijo.2019.4767
11520  Liu YY, Tanikawa C, Ueda K, Matsuda K.  INKA2, a novel p53 target that interacts with the serine/threonine kinase PAK4.  Int. J. Oncol.  2019    PubMed ID: 31081062   DOI: 10.3892/ijo.2019.4786
11554  Matsubara H, Tanaka R, Tateishi T, Yoshida H, Yamaguchi M, Kataoka T.  The human Bcl-2 family member Bcl-rambo and voltage-dependent anion channels manifest a genetic interaction in Drosophila and cooperatively promote the activation of effector caspases in human cultured cells.  Exp. Cell Res.  2019    PubMed ID: 31102594   DOI: 10.1016/j.yexcr.2019.05.015
11555  Chen Y, Sumardika IW, Tomonobu N, Kinoshita R, Inoue Y, Iioka H, Mitsui Y, Saito K, Ruma IMW, Sato H, Yamauchi A, Murata H, Yamamoto KI, Tomida S, Shien K, Yamamoto H, Soh J, Futami J, Kubo M, Putranto EW, Murakami T, Liu M, Hibino T, Nishibori M, Kondo E, Toyooka S, Sakaguchi M.  Critical role of the MCAM-ETV4 axis triggered by extracellular S100A8/A9 in breast cancer aggressiveness.  Neoplasia  2019    PubMed ID: 31100639   DOI: 10.1016/j.neo.2019.04.006
11580  Tanaka J, Mabuchi Y, Hata K, Yasuhara R, Takamatsu K, Kujiraoka S, Yukimori A, Takakura I, Sumimoto H, Fukada T, Azuma M, Akiyama H, Nishimura R, Shimane T, Mishima K.  Sox9 regulates the luminal stem/progenitor cell properties of salivary glands.  Exp. Cell Res.  2019    PubMed ID: 31153924   DOI: 10.1016/j.yexcr.2019.05.030
11621  Arai Y, Kawashita N, Ibrahim MS, Elgendy EM, Daidoji T, Ono T, Takagi T, Nakaya T, Matsumoto K, Watanabe Y.  PB2 mutations arising during H9N2 influenza evolution in the Middle East confer enhanced replication and growth in mammals.  PLoS Pathog.  2019    PubMed ID: 31265471   DOI: 10.1371/journal.ppat.1007919
11624  Furuse Y, Chaimongkol N, Okamoto M, Oshitani H.  Evolutionary and Functional Diversity of the 5' Untranslated Region of Enterovirus D68: Increased Activity of the Internal Ribosome Entry Site of Viral Strains during the 2010s.  Viruses  2019    PubMed ID: 31288421   DOI: 10.3390/v11070626
11643  Ishii J, Suzuki A, Kimura T, Tateyama M, Tanaka T, Yazawa T, Arimasu Y, Chen IS, Aoyama K, Kubo Y, Saitoh S, Mizuno H, Kamma H.  Congenital goitrous hypothyroidism is caused by dysfunction of the iodide transporter SLC26A7.  Commun Biol  2019    PubMed ID: 31372509   DOI: 10.1038/s42003-019-0503-6
11647  Wong JH, Shigemizu D, Yoshii Y, Akiyama S, Tanaka A, Nakagawa H, Narumiya S, Fujimoto A.  Identification of intermediate-sized deletions and inference of their impact on gene expression in a human population.  Genome Med  2019    PubMed ID: 31340865   DOI: 10.1186/s13073-019-0656-4
11716  Makino Y, Jensen NH, Yokota N, Rossner MJ, Akiyama H, Shirahige K, Okada Y.  Single cell RNA-sequencing identified Dec2 as a suppressive factor for spermatogonial differentiation by inhibiting Sohlh1 expression.  Sci Rep  2019    PubMed ID: 30988352   DOI: 10.1038/s41598-019-42578-z
11720  Yamanashi T, Maki M, Kojima K, Shibukawa A, Tsukamoto T, Chowdhury S, Yamanaka A, Takagi S, Sudo Y.  Quantitation of the neural silencing activity of anion channelrhodopsins in Caenorhabditis elegans and their applicability for long-term illumination.  Sci Rep  2019    PubMed ID: 31133660   DOI: 10.1038/s41598-019-44308-x
11766  Su Y, Nichuguti N, Kuroki-Kami A, Fujiwara H.  Sequence-specific retrotransposition of 28S rDNA-specific LINE R2Ol in human cells.  RNA  2019    PubMed ID: 31434792   DOI: 10.1261/rna.072512.119
11845  Kamiki H, Matsugo H, Ishida H, Kobayashi-Kitamura T, Sekine W, Takenaka-Uema A, Murakami S, Horimoto T.  Adaptation of H3N2 canine influenza virus to feline cell culture.  PLoS ONE  2019    PubMed ID: 31600274   DOI: 10.1371/journal.pone.0223507
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12354  Shimizu K, Yamasaki S, Sakurai M, Yumoto N, Ikeda M, Mishima-Tsumagari C, Kukimoto-Niino M, Watanabe T, Kawamura M, Shirouzu M, Fujii SI.  Granzyme A Stimulates pDCs to Promote Adaptive Immunity via Induction of Type I IFN  Front Immunol  2019  10:1450  PubMed ID: 31293597   DOI: 10.3389/fimmu.2019.01450
12362  Takahashi Y, Takahashi H, Stern PL, Kirita T, Tsuboi A.  Expression of Oncofetal Antigen 5T4 in Murine Taste Papillae  Front Cell Neurosci  2019  13:343  PubMed ID: 31417363   DOI: 10.3389/fncel.2019.00343
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11042  Shigenori Inagaki; Masakazu Agetsuma; Takeharu Nagai  A novel fiber-free technique for brain activity imaging in multiple freely behaving mice  SPIE BiOS  2018      DOI: 10.1117/12.2302396
11080  Wang Y, Cao L, Lee CY, Matsuo T, Wu K, Asher G, Tang L, Saitoh T, Russell J, Klewe-Nebenius D, Wang L, Soya S, Hasegawa E, Cherasse Y, Zhou J, Li Y, Wang T, Zhan X, Miyoshi C, Irukayama Y, Cao J, Meeks JP, Gautron L, Wang Z, Sakurai K, Funato H, Sakurai T, Yanagisawa M, Nagase H, Kobayakawa R, Kobayakawa K, Beutler B, Liu Q.  Large-scale forward genetics screening identifies Trpa1 as a chemosensor for predator odor-evoked innate fear behaviors.  Nat Commun  2018  9(1):2041  PubMed ID: 29795268   DOI: 10.1038/s41467-018-04324-3
11137  Iuchi K, Morisada Y, Yoshino Y, Himuro T, Saito Y, Murakami T, Hisatomi H.  Cold atmospheric-pressure nitrogen plasma induces the production of reactive nitrogen species and cell death by increasing intracellular calcium in HEK293T cells.  Arch. Biochem. Biophys.  2018  654:136-145  PubMed ID: 30026027   DOI: 10.1016/j.abb.2018.07.015
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