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19760
etta Takahashi, Nahoko Tomonobu, Rie Kinoshita, Ken-ichi Yamamoto, Hitoshi Murata, Ni Luh Gede Yoni Komalasari, Youyi Chen, Fan Jiang, Yuma Gohara, Toshiki Ochi, I Made Winarsa Ruma, I Wayan Sumardika, Jin Zhou, Tomoko Honjo, Yoshihiko Sakaguchi, Akira Yamauchi, Futoshi Kuribayashi, Eisaku Kondo, Yusuke Inoue, Junichiro Futami, Shinichi Toyooka, Yoshito Zamami, Masakiyo Sakaguchi
Lysyl oxidase-like 4 promotes the invasiveness of triple-negative breast cancer cells by orchestrating the invasive machinery formed by annexin A2 and S100A11 on the cell surface
Frontiers in Oncology
2024
14
DOI: 10.3389/fonc.2024.1371342
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19794
Nakanishi-Matsui M, Matsumoto N, Sun-Wada GH, Wada Y.
Role of the Cytosolic Domain of the a3 Subunit of V-ATPase in the Interaction with Rab7 and Secretory Lysosome Trafficking in Osteoclasts
Biol Pharm Bull
2024
47(1):339-344
PubMed ID: 38296463
DOI: 10.1248/bpb.b23-00833
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19818
Gong L, Voon DC, Nakayama J, Takahashi C, Kohno S.
RB1 loss induces quiescent state through downregulation of RAS signaling in mammary epithelial cells
Cancer Sci
2024
Mar 11
PubMed ID: 38468443
DOI: 10.1111/cas.16122
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21591
Katayama M, Murakami S, Ishida H, Matsugo H, Sekine W, Ohira K, Takenaka-Uema A, Horimoto T.
Antigenic commonality and divergence of hemagglutinin-esterase-fusion protein among influenza D virus lineages revealed using epitope mapping.
J Virol
2024
e0190823
PubMed ID: 38345383
DOI: 10.1128/jvi.01908-23
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21592
Ito F, Yanatori I, Kato K, Toyokuni S.
Protocol for the isolation of GFP-expressing ferroptosis-dependent extracellular vesicles in in vitro cell culture models.
STAR Protoc
2024
5(1):102892
PubMed ID: 38363686
DOI: 10.1016/j.xpro.2024.102892
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21618
Kohyanagi N, Kitamura N, Ikeda S, Shibutani S, Sato K, Ohama T.
PP2A inhibitor SET promotes mTORC1 and Bmi1 signaling through Akt activation and maintains the colony-formation ability of cancer cells.
J Biol Chem
2024
300(1):105584
PubMed ID: 38141761
DOI: 10.1016/j.jbc.2023.105584
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21654
Kobayashi H, Shiba T, Yoshida T, Bolidong D, Kato K, Sato Y, Mochizuki M, Seto T, Kawashiri S, Hanayama R.
Precise analysis of single small extracellular vesicles using flow cytometry.
Sci Rep
2024
14(1):7465
PubMed ID: 38553534
DOI: 10.1038/s41598-024-57974-3
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21667
Kim YJ, Tohyama S, Nagashima T, Nagase M, Hida Y, Hamada S, Watabe AM, Ohtsuka T.
A light-controlled phospholipase C for imaging of lipid dynamics and controlling neural plasticity.
Cell Chem Biol
2024
PubMed ID: 38582083
DOI: 10.1016/j.chembiol.2024.03.001
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21699
Suzuki N, Konuma T, Ikegami T, Akashi S.
Biophysical insights into the dimer formation of human Sirtuin 2.
Protein Sci
2024
33(5):e4994
PubMed ID: 38647411
DOI: 10.1002/pro.4994
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21733
Fujii T, Liang L, Nakayama K, Katoh Y.
Defects in diffusion barrier function of ciliary transition zone caused by ciliopathy variations of TMEM218.
Hum Mol Genet
2024
PubMed ID: 38751342
DOI: 10.1093/hmg/ddae083
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21738
Otsuka Y, Imamura K, Oishi A, Asakawa K, Kondo T, Nakai R, Suga M, Inoue I, Sagara Y, Tsukita K, Teranaka K, Nishimura Y, Watanabe A, Umeyama K, Okushima N, Mitani K, Nagashima H, Kawakami K, Muguruma K, Tsujikawa A, Inoue H.
Phototoxicity avoidance is a potential therapeutic approach for retinal dystrophy caused by EYS dysfunction
JCI Insight
2024
9(8):e174179
PubMed ID: 38646933
DOI: 10.1172/jci.insight.174179
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21753
Tachibana K, Nakamura Y, Do TL, Kihara T, Kawada H, Yamamoto N, Ando K.
Mutations in the SARS-cov-2 spike proteins affected the ACE2-binding affinity during the development of omicron pandemic variants.
Biochem Biophys Res Commun
2024
719:150120
PubMed ID: 38759524
DOI: 10.1016/j.bbrc.2024.150120
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21781
Kitano M, Ohnishi H, Makino A, Miyamoto T, Hayashi Y, Mizuno K, Kaba S, Kawai Y, Kojima T, Kishimoto Y, Yamamoto N, Tomonaga K, Omori K.
An infection model for SARS-CoV-2 using rat transplanted with hiPSC-airway epithelial cells.
Tissue Eng Part A
2024
PubMed ID: 38832872
DOI: 10.1089/ten.TEA.2024.0016
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21812
Yu H, Kohno S, Voon DC, Hussein NH, Zhang Y, Nakayama J, Takegami Y, Takahashi C.
RECK/GPR124-driven WNT signaling in pancreatic and gastric cancer cells.
Cancer Sci
2024
PubMed ID: 38923741
DOI: 10.1111/cas.16258
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21871
Sugiyama Y, Okada S, Daigaku Y, Kusumoto E, Ito T.
Strategic targeting of Cas9 nickase induces large segmental duplications.
Cell Genom
2024
PubMed ID: 39053455
DOI: 10.1016/j.xgen.2024.100610
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21913
Ueno K, Kurazumi H, Suzuki R, Yanagihara M, Mizoguchi T, Harada T, Morikage N, Hamano K.
miR-709 exerts an angiogenic effect through a FGF2 upregulation induced by a GSK3B downregulation
Sci Rep
2024
14(1):11372
PubMed ID: 38762650
DOI: 10.1038/s41598-024-62340-4
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21920
Sekine W, Kamiki H, Ishida H, Matsugo H, Ohira K, Li K, Katayama M, Takenaka-Uema A, Murakami S, Horimoto T.
Adaptation potential of H3N8 canine influenza virus in human respiratory cells.
Sci Rep
2024
14(1):18750
PubMed ID: 39138310
DOI: 10.1038/s41598-024-69509-x
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21932
Miyahara S, Ohuchi M, Nomura M, Hashimoto E, Soga T, Saito R, Hayashi K, Sato T, Saito M, Yamashita Y, Shimada M, Yaegashi N, Yamada H, Tanuma N.
FDX2, an iron-sulfur cluster assembly factor, is essential to prevent cellular senescence, apoptosis or ferroptosis of ovarian cancer cells.
J Biol Chem
2024
107678
PubMed ID: 39151727
DOI: 10.1016/j.jbc.2024.107678
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21934
Tabata K, Kobayashi S, Itakura Y, Gonzalez G, Kabamba CF, Saito S, Sasaki M, Hall WW, Sawa H, Orba Y.
Increased production of orthoflavivirus single-round infectious particles produced in mammalian cells at a suboptimal culture temperature of 28°C.
J Virol Methods
2024
115007
PubMed ID: 39154937
DOI: 10.1016/j.jviromet.2024.115007
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21935
Wang Y, Moh-Moh-Aung A, Wang T, Fujisawa M, Ohara T, Yamamoto KI, Sakaguchi M, Yoshimura T, Matsukawa A.
Exosomal delivery of miR-200b-3p suppresses the growth of hepatocellular carcinoma cells by targeting ERG- and VEGF-mediated angiogenesis.
Gene
2024
148874
PubMed ID: 39159792
DOI: 10.1016/j.gene.2024.148874
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21952
Chiu CT, Tsai HH, Chen JY, Hu CJ, Chen HW.
An Immunoreceptor-Targeting Strategy with Minimalistic C3b Peptide Fusion Enhances SARS-CoV-2 RBD mRNA Vaccine Immunogenicity.
Int J Nanomedicine
2024
19:7201-7214
PubMed ID: 39050877
DOI: 10.2147/IJN.S463546
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21956
Ueno M, Sugiyama H, Li F, Nishimura T, Arakawa H, Chen X, Cheng X, Takeuchi S, Takeshita Y, Takamura T, Miyagi S, Toyama T, Soga T, Masuo Y, Kato Y, Nakamura H, Tsujiguchi H, Hara A, Tajima A, Noguchi-Shinohara M, Ono K, Kurayoshi K, Kobayashi M, Tadokoro Y, Kasahara A, Shoulkamy MI, Maeda K, Ogoshi T, Hirao A.
A Supramolecular Biosensor for Rapid and High-Throughput Quantification of a Disease-Associated Niacin Metabolite.
Anal Chem
2024
PubMed ID: 39183562
DOI: 10.1021/acs.analchem.4c02653
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21967
Okada M, Yamasaki S, Nakazato H, Hirahara Y, Ishibashi T, Kawamura M, Shimizu K, Fujii SI.
ARID1A-Deficient Tumors Acquire Immunogenic Neoantigens during the Development of Resistance to Targeted Therapy.
Cancer Res
2024
84(17):2792-2805
PubMed ID: 39228255
DOI: 10.1158/0008-5472.CAN-23-2846
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21975
Koike T, Sato T, Oe S, Hayashi S, Seki-Omura R, Nakano Y, Iwashita H, Sato Y, Hirahara Y, Kitada M.
CD34 distribution in C-fiber low threshold mechanoreceptors in the mouse dorsal root ganglion and spinal cord.
Brain Res
2024
1846:149227
PubMed ID: 39255903
DOI: 10.1016/j.brainres.2024.149227
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21979
Mori S, Kohyama M, Yasumizu Y, Tada A, Tanzawa K, Shishido T, Kishida K, Jin H, Nishide M, Kawada S, Motooka D, Okuzaki D, Naito R, Nakai W, Kanda T, Murata T, Terao C, Ohmura K, Arase N, Kurosaki T, Fujimoto M, Suenaga T, Kumanogoh A, Sakaguchi S, Ogawa Y, Arase H.
Neoself-antigens are the primary target for autoreactive T cells in human lupus.
Cell
2024
PubMed ID: 39276775
DOI: 10.1016/j.cell.2024.08.025
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21993
Kashiwagi M, Beck G, Kanuka M, Arai Y, Tanaka K, Tatsuzawa C, Koga Y, Saito YC, Takagi M, Oishi Y, Sakaguchi M, Baba K, Ikuno M, Yamakado H, Takahashi R, Yanagisawa M, Murayama S, Sakurai T, Sakai K, Nakagawa Y, Watanabe M, Mochizuki H, Hayashi Y.
A pontine-medullary loop crucial for REM sleep and its deficit in Parkinson's disease.
Cell
2024
PubMed ID: 39303715
DOI: 10.1016/j.cell.2024.08.046
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17565
Arai Y, Yamanaka I, Okamoto T, Isobe A, Nakai N, Kamimura N, Suzuki T, Daidoji T, Ono T, Nakaya T, Matsumoto K, Okuzaki D, Watanabe Y.
Stimulation of interferon-β responses by aberrant SARS-CoV-2 small viral RNAs acting as retinoic acid-inducible gene-I agonists
iScience
2023
26(1):105742
PubMed ID: 36507221
DOI: 10.1016/j.isci.2022.105742
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17804
Toshiki Takahashi, Jun Shirai, Miyo Matsuda, Sae Nakanaga, Shin Matsushita, Kei Wakita, Mizuki Hayashishita, Rigel Suzuki, Aya Noguchi, Naoto Yokota, and Hiroyuki Kawahara
Protein quality control machinery supports primary ciliogenesis by eliminating GDP-bound Rab8- family GTPases
iScience
2023
DOI: 10.1016/ j.isci.2023.106652
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18094
Nakajima M, Kawahara R, Simizu S.
Cofilin promotes vasculogenic mimicry by regulating the actin cytoskeleton in human breast cancer cells
FEBS Lett
2023
597(8):1114-1124
PubMed ID: 36737242
DOI: 10.1002/1873-3468.14594
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18098
Gohara Y, Tomonobu N, Kinoshita R, Futami J, Audebert L, Chen Y, Komalasari NLGY, Jiang F, Yoshizawa C, Murata H, Yamamoto KI, Watanabe M, Kumon H, Sakaguchi M.
Novel extracellular role of REIC/Dkk-3 protein in PD-L1 regulation in cancer cells
J Mol Med (Berl)
2023
101(4):431-447
PubMed ID: 36869893
DOI: 10.1007/s00109-023-02292-w
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18106
Komalasari NLGY, Tomonobu N, Kinoshita R, Chen Y, Sakaguchi Y, Gohara Y, Jiang F, Yamamoto KI, Murata H, Ruma IMW, Sumardika IW, Zhou J, Yamauchi A, Kuribayashi F, Inoue Y, Toyooka S, Sakaguchi M.
Lysyl oxidase-like 4 exerts an atypical role in breast cancer progression that is dependent on the enzymatic activity that targets the cell-surface annexin A2
Front Oncol
2023
13:1142907
PubMed ID: 37091157
DOI: 10.3389/fonc.2023.1142907
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18139
Hoshino N, Kanadome T, Takasugi T, Itoh M, Kaneko R, Inoue YU, Inoue T, Hirabayashi T, Watanabe M, Matsuda T, Nagai T, Tarusawa E, Yagi T.
Visualization of trans homophilic interaction of clustered protocadherin in neurons
Proc Natl Acad Sci U S A
2023
120(38):e2301003120
PubMed ID: 37695902
DOI: 10.1073/pnas.2301003120
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18171
Kikuchi M, Takase S, Konuma T, Noritsugu K, Sekine S, Ikegami T, Ito A, Umehara T.
GAS41 promotes H2A.Z deposition through recognition of the N terminus of histone H3 by the YEATS domain
Proc Natl Acad Sci U S A
2023
120(43):e2304103120
PubMed ID: 37844223
DOI: 10.1073/pnas.2304103120
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19540
Furukawa Y, Ishii M, Ando J, Ikeda K, Igarashi KJ, Kinoshita S, Azusawa Y, Toyota T, Honda T, Nakanishi M, Ohshima K, Masuda A, Yoshida E, Kitade M, Porteus M, Terao Y, Nakauchi H, Ando M.
iPSC-derived hypoimmunogenic tissue resident memory T cells mediate robust anti-tumor activity against cervical cancer
Cell Rep Med
2023
4(12):101327
PubMed ID: 38091985
DOI: 10.1016/j.xcrm.2023.101327
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19549
Uemura K, Nobori H, Sato A, Toba S, Kusakabe S, Sasaki M, Tabata K, Matsuno K, Maeda N, Ito S, Tanaka M, Anraku Y, Kita S, Ishii M, Kanamitsu K, Orba Y, Matsuura Y, Hall WW, Sawa H, Kida H, Matsuda A, Maenaka K.
2-thiouridine is a broad-spectrum antiviral nucleoside analogue against positive-strand RNA viruses
Proc Natl Acad Sci U S A
2023
120(42):e2304139120
PubMed ID: 37831739
DOI: 10.1073/pnas.2304139120
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19597
Hatanaka A, Nakada S, Matsumoto G, Satoh K, Aketa I, Watanabe A, Hirakawa T, Tsujita T, Waku T, Kobayashi A.
The transcription factor NRF1 (NFE2L1) activates aggrephagy by inducing p62 and GABARAPL1 after proteasome inhibition to maintain proteostasis
Sci Rep
2023
13(1):14405
PubMed ID: 37658135
DOI: 10.1038/s41598-023-41492-9
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19624
Park G, Fukasawa K, Horie T, Masuo Y, Inaba Y, Tatsuno T, Yamada T, Tokumura K, Iwahashi S, Iezaki T, Kaneda K, Kato Y, Ishigaki Y, Mieda M, Tanaka T, Ogawa K, Ochi H, Sato S, Shi YB, Inoue H, Lee H, Hinoi E.
l-Type amino acid transporter 1 in hypothalamic neurons in mice maintains energy and bone homeostasis
JCI Insight
2023
8(7):e154925
PubMed ID: 36862514
DOI: 10.1172/jci.insight.154925
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19632
ukasawa K, Lyu J, Kubo T, Tanaka Y, Suzuki A, Horie T, Tomizawa A, Osumi R, Iwahashi S, Tokumura K, Murata M, Kobayashi M, Todo T, Hirao A, Hinoi E.
MEK5-ERK5 Axis Promotes Self-renewal and Tumorigenicity of Glioma Stem Cells
Cancer Res Commun
2023
3(1):148-159
PubMed ID: 36968222
DOI: 10.1158/2767-9764.CRC-22-0243
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19650
Zhang S, Tsuji H, Jin H, Kitagori K, Akizuki S, Nakashima R, Yoshifuji H, Tanaka M, Arase H, Ohmura K, Morinobu A.
Rheumatoid factor recognizes specific domains of the IgG heavy chain complexed with HLA class II molecules
Rheumatology (Oxford)
2023
62(9):3151-3155.
PubMed ID: 36645239
DOI: 10.1093/rheumatology/kead024
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19789
Hagkarim NC, Hajkarim MC, Suzuki T, Fujiwara T, Winkler GS, Stewart GS, Grand RJ.
Disruption of the Mammalian Ccr4-Not Complex Contributes to Transcription-Mediated Genome Instability
Cells
2023
12(14):1868
PubMed ID: 37508532
DOI: 10.3390/cells12141868
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19919
Wuputra K, Tsai MH, Kato K, Ku CC, Pan JB, Yang YH, Saito S, Wu CC, Lin YC, Cheng KH, Kuo KK, Noguchi M, Nakamura Y, Yoshioka T, Wu DC, Lin CS, Yokoyama KK.
Jdp2 is a spatiotemporal transcriptional activator of the AhR via the Nrf2 gene battery
Inflamm Regen
2023
43(1):42
PubMed ID: 37596694
DOI: 10.1186/s41232-023-00290-6
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19958
Hirabayashi D, Yamamoto KI, Maruyama A, Tomonobu N, Kinoshita R, Chen Y, Komalasari NLGY, Murata H, Gohara Y, Jiang F, Zhou J, Ruma IMW, Sumardika IW, Yamauchi A, Kuribayashi F, Toyooka S, Inoue Y, Sakaguchi M.
LOXL1 and LOXL4 are novel target genes of the Zn2+-bound form of ZEB1 and play a crucial role in the acceleration of invasive events in triple-negative breast cancer cells
Front Oncol
2023
13:1142886
PubMed ID: 36910659
DOI: 10.3389/fonc.2023.1142886
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19991
Mitamura R, Nakano M, Isono M, Kurosawa K, Fukami T, Nakajima M.
NEAT1_2 and DAZAP1, Paraspeckle Components, Interact with PXR to Negatively Regulate CYP3A4 Induction
Drug Metab Dispos
2023
51(10):1230-1237
PubMed ID: 37349114
DOI: 10.1124/dmd.122.001065
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20922
Sasaki M, Tabata K, Kishimoto M, Itakura Y, Kobayashi H, Ariizumi T, Uemura K, Toba S, Kusakabe S, Maruyama Y, Iida S, Nakajima N, Suzuki T, Yoshida S, Nobori H, Sanaki T, Kato T, Shishido T, Hall WW, Orba Y, Sato A, Sawa H.
S-217622, a SARS-CoV-2 main protease inhibitor, decreases viral load and ameliorates COVID-19 severity in hamsters.
Sci Transl Med
2023
15(679):eabq4064
PubMed ID: 36327352
DOI: 10.1126/scitranslmed.abq4064
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20993
Okamoto K, Kamikubo Y, Yamauchi K, Okamoto S, Takahashi M, Ishida Y, Koike M, Ikegaya Y, Sakurai T, Hioki H.
Specific AAV2/PHP.eB-mediated gene transduction of CA2 pyramidal cells via injection into the lateral ventricle.
Sci Rep
2023
13(1):323
PubMed ID: 36609635
DOI: 10.1038/s41598-022-27372-8
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21011
Hiyamizu S, Qiu H, Vuolo L, Stevenson NL, Shak C, Heesom KJ, Hamada Y, Tsurumi Y, Chiba S, Katoh Y, Stephens DJ, Nakayama K.
Multiple interactions of the dynein-2 complex with the IFT-B complex are required for effective IFT.
J Cell Sci
2023
PubMed ID: 36632779
DOI: 10.1242/jcs.260462
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21015
Shoji H, Kitao K, Miyazawa T, Nakagawa S.
Potentially reduced fusogenicity of syncytin-2 in New World monkeys.
FEBS Open Bio
2023
PubMed ID: 36647789
DOI: 10.1002/2211-5463.13555
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21065
Morihiro K, Osumi H, Morita S, Hattori T, Baba M, Harada N, Ohashi R, Okamoto A.
Oncolytic Hairpin DNA Pair: Selective Cytotoxic Inducer through MicroRNA-Triggered DNA Self-Assembly.
J Am Chem Soc
2023
145(1):135-142
PubMed ID: 36538570
DOI: 10.1021/jacs.2c08974
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21076
Sato M, Maishi N, Hida Y, Yanagawa-Matsuda A, Alam MT, Sakakibara-Konishi J, Nam JM, Onodera Y, Konno S, Hida K.
Angiogenic inhibitor pre-administration improves the therapeutic effects of immunotherapy.
Cancer Med
2023
PubMed ID: 36808261
DOI: 10.1002/cam4.5696
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21092
Yoshimoto S, Suzuki T, Otani N, Takahashi D, Toshima K, Dohmae N, Simizu S.
Destabilization of vitelline membrane outer layer protein 1 homolog (VMO1) by C-mannosylation.
FEBS Open Bio
2023
PubMed ID: 36680395
DOI: 10.1002/2211-5463.13561
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21101
Ota A, Morita H, Naganuma T, Miyamoto M, Jojima K, Nojiri K, Matsuda J, Kihara A.
Bifunctional DEGS2 has higher hydroxylase activity toward substrates with very-long-chain fatty acids in the production of phytosphingosine-ceramides.
J Biol Chem
2023
104603
PubMed ID: 36907437
DOI: 10.1016/j.jbc.2023.104603
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17485
Tanikawa S, Ebisu Y, Sedlačík T, Semba S, Nonoyama T, Kurokawa T, Hirota A, Takahashi T, Yamaguchi K, Imajo M, Kato H, Nishimura T, Tanei ZI, Tsuda M, Nemoto T, Gong JP, Tanaka S.
Engineering of an electrically charged hydrogel implanted into a traumatic brain injury model for stepwise neuronal tissue reconstruction
Sci Rep
2023
13(1):2233
PubMed ID: 36788295
DOI: 10.1038/s41598-023-28870-z
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21104
Kawano T, Kashiwagi M, Kanuka M, Chen CK, Yasugaki S, Hatori S, Miyazaki S, Tanaka K, Fujita H, Nakajima T, Yanagisawa M, Nakagawa Y, Hayashi Y.
ER proteostasis regulators cell-non-autonomously control sleep.
Cell Rep
2023
42(3):112267
PubMed ID: 36924492
DOI: 10.1016/j.celrep.2023.112267
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21158
Tao F, Kitamura K, Hanada S, Sugimoto K, Furihata T, Kojima N.
Rapid and Stable Formation Method of Human Astrocyte Spheroid in a High Viscous Methylcellulose Medium and Its Functional Advantages.
Bioengineering (Basel)
2023
10(3)
PubMed ID: 36978740
DOI: 10.3390/bioengineering10030349
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21159
Watanabe T, Narahari A, Bhardwaj E, Kuriyama K, Nishimura M, Izumi T, Fujimuro M, Ohno S.
Conserved cysteine residues in Kaposi's sarcoma herpesvirus ORF34 are necessary for viral production and viral pre-initiation complex formation.
bioRxiv
2023
PubMed ID: 36945456
DOI: 10.1101/2023.03.08.531831
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21179
Noritsugu K, Suzuki T, Dodo K, Ohgane K, Ichikawa Y, Koike K, Morita S, Umehara T, Ogawa K, Sodeoka M, Dohmae N, Yoshida M, Ito A.
Lysine long-chain fatty acylation regulates the TEAD transcription factor.
Cell Rep
2023
112388
PubMed ID: 37060904
DOI: 10.1016/j.celrep.2023.112388
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21219
Jojima K, Kihara A.
Metabolism of sphingadiene and characterization of the sphingadiene-producing enzyme FADS3.
Biochim Biophys Acta Mol Cell Biol Lipids
2023
1868(8):159335
PubMed ID: 37209771
DOI: 10.1016/j.bbalip.2023.159335
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21222
Takahashi T, Shirai J, Matsuda M, Nakanaga S, Matsushita S, Wakita K, Hayashishita M, Suzuki R, Noguchi A, Yokota N, Kawahara H.
Protein quality control machinery supports primary ciliogenesis by eliminating GDP-bound Rab8-family GTPases.
iScience
2023
26(5):106652
PubMed ID: 37182096
DOI: 10.1016/j.isci.2023.106652
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21248
Kasuga Y, Ouda R, Watanabe M, Sun X, Kimura M, Hatakeyama S, Kobayashi KS.
FBXO11 constitutes a major negative regulator of MHC class II through ubiquitin-dependent proteasomal degradation of CIITA.
Proc Natl Acad Sci U S A
2023
120(24):e2218955120
PubMed ID: 37279268
DOI: 10.1073/pnas.2218955120
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21258
Nishi K, Yoshii A, Abell L, Zhou B, Frausto R, Ritterhoff J, McMillen TS, Sweet I, Wang Y, Gao C, Tian R.
Branched-chain keto acids inhibit mitochondrial pyruvate carrier and suppress gluconeogenesis in hepatocytes.
Cell Rep
2023
42(6):112641
PubMed ID: 37310861
DOI: 10.1016/j.celrep.2023.112641
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21261
Hiyamizu S, Qiu H, Tsurumi Y, Hamada Y, Katoh Y, Nakayama K.
Dynein-2-driven intraciliary retrograde trafficking indirectly requires multiple interactions of IFT54 in the IFT-B complex with the dynein-2 complex.
Biol Open
2023
PubMed ID: 37309605
DOI: 10.1242/bio.059976
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21265
Shimohata A, Rai D, Akagi T, Usui S, Ogiwara I, Kaneda M.
The intracellular C-terminal domain of mGluR6 contains ER retention motifs.
Mol Cell Neurosci
2023
103875
PubMed ID: 37352898
DOI: 10.1016/j.mcn.2023.103875
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21270
Yamaguchi S, Kamino M, Hamamura M, Otsuguro KI.
The cytosolic N-terminal region of heterologously-expressed transmembrane channel-like protein 1 (TMC1) can be cleaved in HEK293 cells.
PLoS One
2023
18(6):e0287249
PubMed ID: 37352201
DOI: 10.1371/journal.pone.0287249
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21278
Okada M, Shimizu K, Nakazato H, Yamasaki S, Fujii SI.
Detection of mutant antigen-specific T cell receptors against multiple myeloma for T cell engineering.
Mol Ther Methods Clin Dev
2023
29:541-555
PubMed ID: 37359417
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Morishita K, Kondo J, Sakon D, Hayashibara A, Tamura I, Shimizu K, Takamatsu S, Murata K, Kamada Y, Miyoshi E.
Prohaptoglobin is a possible prognostic biomarker for colorectal cancer.
Biochem Biophys Res Commun
2023
672:72-80
PubMed ID: 37343317
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Tanaka Y, Morozumi A, Hirokawa N.
Nodal flow transfers polycystin to determine mouse left-right asymmetry.
Dev Cell
2023
PubMed ID: 37413993
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21312
Omata K, Nomura I, Hirata A, Yonezuka Y, Muto H, Kuriki R, Jimbo K, Ogasa K, Kato T.
Isolation and evaluation of erythroid progenitors in the livers of larval, froglet, and adult Xenopus tropicalis.
Biol Open
2023
PubMed ID: 37421150
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Matsuura-Suzuki E, Toh H, Iwasaki S.
Human-rabbit Hybrid Translation System to Explore the Function of Modified Ribosomes.
Bio Protoc
2023
13(13):e4714
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Tokuma H, Sakano D, Tanabe K, Tanizawa Y, Shiraki N, Kume S.
Selective proteasome degradation of C-terminally-truncated human WFS1 in pancreatic beta cells.
FEBS Open Bio
2023
PubMed ID: 37440664
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Takahashi G, Miyaoka Y.
Large-scale single-cell cloning of genome-edited cultured human cells by On-chip SPiS.
STAR Protoc
2023
4(3):102364
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Goto M, Nishimura G, Sato H, Yamaguchi Y, Morimoto N, Hashimoto H, Takahashi N.
Pharmacological profile of upacicalcet, a novel positive allosteric modulator of calcium-sensing receptor, in vitro and in vivo.
Eur J Pharmacol
2023
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Komuro H, Shinohara S, Fukushima Y, Demachi-Okamura A, Muraoka D, Masago K, Matsui T, Sugita Y, Takahashi Y, Nishida R, Takashima C, Ohki T, Shigematsu Y, Watanabe F, Adachi K, Fukuyama T, Hamana H, Kishi H, Miura D, Tanaka Y, Onoue K, Onoguchi K, Yamashita Y, Stratford R, Clancy T, Yamaguchi R, Kuroda H, Doi K, Iwata H, Matsushita H.
Single-cell sequencing on CD8+ TILs revealed the nature of exhausted T cells recognizing neoantigen and cancer/testis antigen in non-small cell lung cancer.
J Immunother Cancer
2023
11(8)
PubMed ID: 37544663
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Kanadome T, Hoshino N, Nagai T, Yagi T, Matsuda T.
Visualization of trans-interactions of a protocadherin-α between processes originating from single neurons.
iScience
2023
26(7):107238
PubMed ID: 37534169
DOI: 10.1016/j.isci.2023.107238
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21367
Tsuji K, Kikuchi E, Takashima Y, Shoji T, Takahashi H, Ito S, Morinaga D, Kashima M, Maeda M, Kitai H, Kikuchi J, Sakakibara-Konishi J, Konno S.
Inhibition of non-homologous end joining mitigates paclitaxel resistance resulting from mitotic slippage in non-small cell lung cancer
Cell Cycle
2023
22(17):1854-1864
PubMed ID: 37592765
DOI: 10.1080/15384101.2023.2243761
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21373
Suzuki MM, Iijima K, Ogami K, Shinjo K, Murofushi Y, Xie J, Wang X, Kitano Y, Mamiya A, Kibe Y, Nishimura T, Ohka F, Saito R, Sato S, Kobayashi J, Yao R, Miyata K, Kataoka K, Suzuki HI, Kondo Y.
TUG1-mediated R-loop resolution at microsatellite loci as a prerequisite for cancer cell proliferation.
Nat Commun
2023
14(1):4521
PubMed ID: 37607907
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Xu J, Hashino T, Tanaka R, Kawaguchi K, Yoshida H, Kataoka T.
The BCL-2 family protein BCL-RAMBO interacts and cooperates with GRP75 to promote its apoptosis signaling pathway.
Sci Rep
2023
13(1):14041
PubMed ID: 37640805
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21398
Kanao E, Ishida K, Mizuta R, Li Y, Imami K, Tanigawa T, Sasaki Y, Akiyoshi K, Adachi J, Otsuka K, Ishihama Y, Kubo T.
Rapid and Highly Efficient Purification of Extracellular Vesicles Enabled by a TiO2 Hybridized Spongy-like Polymer.
Anal Chem
2023
PubMed ID: 37703188
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21416
Sogawa A, Komori R, Yanagitani K, Ohfurudono M, Tsuru A, Kadoi K, Kimata Y, Yoshida H, Kohno K.
Signal sequence-triage is activated by translocon obstruction sensed by an ER stress sensor IRE1α.
Cell Struct Funct
2023
PubMed ID: 37766570
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Takeuchi K, Tabe S, Takahashi K, Aoshima K, Matsuo M, Ueno Y, Furukawa Y, Yamaguchi K, Ohtsuka M, Morinaga S, Miyagi Y, Yamaguchi T, Tanimizu N, Taniguchi H.
Incorporation of human iPSC-derived stromal cells creates a pancreatic cancer organoid with heterogeneous cancer-associated fibroblasts.
Cell Rep
2023
42(11):113420
PubMed ID: 37955987
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Nishida H, Kanao E, Ishihama Y.
Centrifugal Gel Crushing Tips for Gel-Based Proteome Analysis.
Anal Chem
2023
PubMed ID: 38055789
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21514
Nomura M, Ohuchi M, Sakamoto Y, Kudo K, Yaku K, Soga T, Sugiura Y, Morita M, Hayashi K, Miyahara S, Sato T, Yamashita Y, Ito S, Kikuchi N, Sato I, Saito R, Yaegashi N, Fukuhara T, Yamada H, Shima H, Nakayama KI, Hirao A, Kawasaki K, Arai Y, Akamatsu S, Tanuma SI, Sato T, Nakagawa T, Tanuma N.
Niacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma.
Nat Commun
2023
14(1):8095
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21660
Agata A, Ohtsuka S, Noji R, Gotoh H, Ono K, Nomura T.
A Neanderthal/Denisovan GLI3 variant contributes to anatomical variations in mice.
Front Cell Dev Biol
2023
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Mizuta H, Takakusaki A, Suzuki T, Otake K, Dohmae N, Simizu S.
C-mannosylation regulates stabilization of RAMP1 protein and RAMP1-mediated cell migration
FEBS J
2023
290(1):196-208
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Haraguchi-Suzuki K, Kawabata-Iwakawa R, Suzuki T, Suto T, Takazawa T, Saito S.
Local anesthetic lidocaine induces growth suppression of HeLa cells by decreasing and changing the cellular localization of the proliferation marker Ki-67
Genes Cells
2022
27(11):675-684
PubMed ID: 36074048
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Miku Akishino, Yuko Aoki, Hajime Baba, Makio Asakawa, Yoichiro Hama, Susumu Mitsutake
Red algae-derived isofloridoside activates the sweet taste receptor T1R2/T1R3
Food Bioscience
2022
50:102186
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17529
Tsukida K, Muramatsu SI, Osaka H, Yamagata T, Muramatsu K.
WDR45 variants cause ferrous iron loss due to impaired ferritinophagy associated with nuclear receptor coactivator 4 and WD repeat domain phosphoinositide interacting protein 4 reduction
Brain Commun
2022
4(6):fcac304
PubMed ID: 36751498
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Kamiki H, Murakami S, Nishikaze T, Hiono T, Igarashi M, Furuse Y, Matsugo H, Ishida H, Katayama M, Sekine W, Muraki Y, Takahashi M, Takenaka-Uema A, Horimoto T.
Influenza A Virus Agnostic Receptor Tropism Revealed Using a Novel Biological System with Terminal Sialic Acid Knockout Cells
J Virol
2022
96(15):e0041622
PubMed ID: 35862707
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Yamashita F, Kaieda T, Shimomura T, Kawaguchi M, Lin CY, Johnson MD, Tanaka H, Kiwaki T, Fukushima T, Kataoka H.
Role of the polycystic kidney disease domain in matriptase chaperone activity and localization of hepatocyte growth factor activator inhibitor-1
FEBS J
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289(12):3422-3439
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Saito S, Funayama K, Kato W, Okuda M, Kawamoto M, Matsubara T, Sato T, Sato A, Otsuguro S, Sasaki M, Orba Y, Sawa H, Maenaka K, Shindo K, Imoto M, Arai MA.
Dihydromaniwamycin E, a Heat-Shock Metabolite from Thermotolerant Streptomyces sp. JA74, Exhibiting Antiviral Activity against Influenza and SARS-CoV-2 Viruses
J Nat Prod
2022
85(11):2583-2591
PubMed ID: 36223390
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Wei Z, Shimizu K, Sarii RS, Muthusinghe DS, Lokupathirage SMW, Nio-Kobayashi J, Yoshimatsu K.
Pathological Studies on Hantaan Virus-Infected Mice Simulating Severe Hemorrhagic Fever with Renal Syndrome
Viruses
2022
14(10):2247
PubMed ID: 36298802
DOI: 10.3390/v14102247
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Yamauchi K, Okamoto S, Ishida Y, Konno K, Hoshino K, Furuta T, Takahashi M, Koike M, Isa K, Watanabe M, Isa T, Hioki H.
Fluorochromized tyramide-glucose oxidase as a multiplex fluorescent tyramide signal amplification system for histochemical analysis
Sci Rep
2022
12(1):14807
PubMed ID: 36097273
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Matsumura Y, To TK, Kunieda T, Kohno H, Kakutani T, Kubo T.
Mblk-1/E93, an ecdysone related-transcription factor, targets synaptic plasticity-related genes in the honey bee mushroom bodies
Sci Rep
2022
12(1):21367
PubMed ID: 36494426
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Ohshima T, Yamamoto H, Sakamaki Y, Saito C, Mizushima N.
NCOA4 drives ferritin phase separation to facilitate macroferritinophagy and microferritinophagy
J Cell Biol
2022
221(10):e202203102
PubMed ID: 36066504
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Takeuchi Y, Ushimaru K, Kaneda K, Maruyama C, Ito T, Yamanaka K, Ogasawara Y, Katano H, Kato Y, Dairi T, Hamano Y.
First direct evidence for direct cell-membrane penetrations of polycationic homopoly(amino acid)s produced by bacteria
Commun Biol
2022
5(1):1132
PubMed ID: 36289442
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Suzuki T, Hoshina M, Nishijima S, Hoshina N, Kikuguchi C, Tomohiro T, Fukao A, Fujiwara T, Yamamoto T.
Regulation of CCR4-NOT complex deadenylase activity and cellular responses by MK2-dependent phosphorylation of CNOT2
RNA Biol
2022
19(1):234-246
PubMed ID: 35129087
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Narita M, Denk T, Matsuo Y, Sugiyama T, Kikuguchi C, Ito S, Sato N, Suzuki T, Hashimoto S, Machová I, Tesina P, Beckmann R, Inada T.
A distinct mammalian disome collision interface harbors K63-linked polyubiquitination of uS10 to trigger hRQT-mediated subunit dissociation
Nat Commun
2022
13(1):6411
PubMed ID: 36302773
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Tsuji H, Ohmura K, Jin H, Naito R, Arase N, Kohyama M, Suenaga T, Sakakibara S, Kochi Y, Okada Y, Yamamoto K, Kikutani H, Morinobu A, Mimori T, Arase H.
Anti-dsDNA antibodies recognize DNA presented on HLA class II molecules of systemic lupus erythematosus risk alleles.
Arthritis Rheumatol
2022
PubMed ID: 34164946
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Tanaka K, Kandori S, Sakka S, Nitta S, Tanuma K, Shiga M, Nagumo Y, Negoro H, Kojima T, Mathis BJ, Shimazui T, Watanabe M, Sato TA, Miyamoto T, Matsuzaka T, Shimano H, Nishiyama H.
ELOVL2 promotes cancer progression by inhibiting cell apoptosis in renal cell carcinoma.
Oncol Rep
2022
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PubMed ID: 34841437
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Arase N, Tsuji H, Takamatsu H, Jin H, Konaka H, Hamaguchi Y, Tonomura K, Kotobuki Y, Ueda-Hayakawa I, Matsuoka S, Hirano T, Yorifuji H, Murota H, Ohmura K, Nakashima R, Sato T, Kumanogoh A, Katayama I, Arase H, Fujimoto M.
Cell surface-expressed Ro52/IgG/HLA-DR complex is targeted by autoantibodies in patients with inflammatory myopathies.
J Autoimmun
2022
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PubMed ID: 34896887
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Qiu H, Tsurumi Y, Katoh Y, Nakayama K.
Combinations of deletion and missense variations of the dynein-2 DYNC2LI1 subunit found in skeletal ciliopathies cause ciliary defects.
Sci Rep
2022
12(1):31
PubMed ID: 34997029
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20522
Hiraiwa M, Fukasawa K, Iezaki T, Sabit H, Horie T, Tokumura K, Iwahashi S, Murata M, Kobayashi M, Suzuki A, Park G, Kaneda K, Todo T, Hirao A, Nakada M, Hinoi E.
SMURF2 phosphorylation at Thr249 modifies glioma stemness and tumorigenicity by regulating TGF-β receptor stability.
Commun Biol
2022
5(1):22
PubMed ID: 35017630
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Nomura T, Nagao K, Shirai R, Gotoh H, Umeda M, Ono K.
Temperature sensitivity of Notch signaling underlies species-specific developmental plasticity and robustness in amniote brains.
Nat Commun
2022
13(1):96
PubMed ID: 35013223
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Wuputra K, Tsai MH, Kato K, Yang YH, Pan JB, Ku CC, Noguchi M, Kishikawa S, Nakade K, Chen HL, Liu CJ, Nakamura Y, Kuo KK, Lin YC, Chan TF, Wu DC, Hou MF, Huang SK, Lin CS, Yokoyama KK.
Dimethyl sulfoxide stimulates the AhR-Jdp2 axis to control ROS accumulation in mouse embryonic fibroblasts
Cell Biol Toxicol
2022
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PubMed ID: 33723743
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Jin H, Kishida K, Arase N, Matsuoka S, Nakai W, Kohyama M, Suenaga T, Yamamoto K, Sasazuki T, Arase H.
Abrogation of self-tolerance by misfolded self-antigens complexed with MHC class II molecules.
Sci Adv
2022
8(9):eabj9867
PubMed ID: 35245125
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Murakami Y, Masaki M, Miyazaki S, Oketani R, Hayashi Y, Yanagisawa M, Honjoh S, Kano H.
Spectroscopic second and third harmonic generation microscopy using a femtosecond laser source in the third near-infrared (NIR-III) optical window.
Biomed Opt Express
2022
13(2):694-708
PubMed ID: 35284173
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Miyajima Y, Noguchi S, Tanaka Y, Li JR, Nishimura H, Kishima M, Lim J, Furuhata E, Suzuki T, Kasukawa T, Suzuki H.
Prediction of transcription factors associated with DNA demethylation during human cellular development.
Chromosome Res
2022
30(1):109-121
PubMed ID: 35142952
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Chino H, Yamasaki A, Ode KL, Ueda HR, Noda NN, Mizushima N.
Phosphorylation by casein kinase 2 enhances the interaction between ER-phagy receptor TEX264 and ATG8 proteins.
EMBO Rep
2022
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PubMed ID: 35417087
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Nashimoto Y, Matsushita F, Dijkstra JM, Nakamura Y, Akiyama H, Hamako J, Morita T, Araki S, Matsui T.
Bitiscetin-3, a Novel C-Type Lectin-like Protein Cloned from the Venom Gland of the Viper Bitis arietans, Induces Platelet Agglutination and Inhibits Binding of Von Willebrand Factor to Collagen.
Toxins (Basel)
2022
14(4)
PubMed ID: 35448845
DOI: 10.3390/toxins14040236
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Kamo H, Kawahara R, Simizu S.
Tyrosinase suppresses vasculogenic mimicry in human melanoma cells.
Oncol Lett
2022
23(5):169
PubMed ID: 35496574
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Satoda Y, Noguchi T, Fujii T, Taniguchi A, Katoh Y, Nakayama K.
BROMI/TBC1D32 together with CCRK/CDK20 and FAM149B1/JBTS36 contributes to IFT turnaround involving ICK/CILK1.
Mol Biol Cell
2022
mbcE22030089
PubMed ID: 35609210
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Kamada H, Yasuhira S, Shibazaki M, Amano H, Maesawa C.
DUSP4 Inactivation Leads to Reduced Extracellular Signal‒Regulated Kinase Activity through Upregulation of DUSP6 in Melanoma Cells
J Invest Dermatol
2022
S0022-202X(22)00126-9
PubMed ID: 35189148
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Ishida Y, Tasaki K, Katoh Y, Nakayama K.
Molecular basis underlying the ciliary defects caused by IFT52 variations found in skeletal ciliopathies.
Mol Biol Cell
2022
mbcE22050188
PubMed ID: 35704471
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Hada M, Miura H, Tanigawa A, Matoba S, Inoue K, Ogonuki N, Hirose M, Watanabe N, Nakato R, Fujiki K, Hasegawa A, Sakashita A, Okae H, Miura K, Shikata D, Arima T, Shirahige K, Hiratani I, Ogura A.
Highly rigid H3.1/H3.2-H3K9me3 domains set a barrier for cell fate reprogramming in trophoblast stem cells
Genes Dev
2022
36(1-2):84-102
PubMed ID: 34992147
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Sasaki K, Suzuki M, Sonoda T, Schneider-Poetsch T, Ito A, Takagi M, Fujishiro S, Sohtome Y, Dodo K, Umehara T, Aburatani H, Shin-Ya K, Nakao Y, Sodeoka M, Yoshida M.
Visualization of the dynamic interaction between nucleosomal histone H3K9 tri-methylation and HP1α chromodomain in living cells
Cell Chem Biol
2022
S2451-9456(22)00198-2
PubMed ID: 35728598
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Matsuura-Suzuki E, Shimazu T, Takahashi M, Kotoshiba K, Suzuki T, Kashiwagi K, Sohtome Y, Akakabe M, Sodeoka M, Dohmae N, Ito T, Shinkai Y, Iwasaki S.
METTL18-mediated histidine methylation of RPL3 modulates translation elongation for proteostasis maintenance
Elife
2022
11:e72780
PubMed ID: 35674491
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Yamada T, Fukasawa K, Horie T, Kadota T, Lyu J, Tokumura K, Ochiai S, Iwahashi S, Suzuki A, Park G, Ueda R, Yamamoto M, Kitao T, Shirahase H, Ochi H, Sato S, Iezaki T, Hinoi E.
The role of CDK8 in mesenchymal stem cells in controlling osteoclastogenesis and bone homeostasis.
Stem Cell Reports
2022
PubMed ID: 35777359
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16732
Zhu Z, Kitano T, Morimatsu M, Tanaka A, Morioka R, Lin X, Orino K, Yoshikawa Y.
BRCA2 C-Terminal RAD51-Binding Domain Confers Resistance to DNA-Damaging Agents
Int J Mol Sci
2022
23(7):4060
PubMed ID: 35409418
DOI: 10.3390/ijms23074060
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16747
Fujii K, Morita S, Mochizuki M, Shibuya-Takahashi R, Fujimori H, Yamaguchi K, Abe J, Yamazaki T, Imai T, Sugamura K, Yasuda J, Satoh K, Sato I, Saito-Koyama R, Fujishima F, Sasano H, Kato Y, Matsuura K, Asada Y, Tamai K.
Establishment of a monoclonal antibody against glycosylated CD271 specific for cancer cells in immunohistochemistry
Cancer Sci . 2022 Mar 28
2022
Mar 28
PubMed ID: 35343032
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Song W, Isaji T, Nakano M, Liang C, Fukuda T, Gu J.
O-GlcNAcylation regulates β1,4-GlcNAc-branched N-glycan biosynthesis via the OGT/SLC35A3/GnT-IV axis
FASEB J
2022
36(2):e22149
PubMed ID: 34981577
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Kitanishi T, Tashiro M, Kitanishi N, Mizuseki K.
Intersectional, anterograde transsynaptic targeting of neurons receiving monosynaptic inputs from two upstream regions
Commun Biol
2022
5(1):149
PubMed ID: 35190665
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Otsuka K, Sawai-Ogawa M, Kihara A.
Formation of fatty alcohols-components of meibum lipids-by the fatty acyl-CoA reductase FAR2 is essential for dry eye prevention
FASEB J
2022
36(4):e22216
PubMed ID: 35238077
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Takahashi S, Shibutani S, Iwata H.
Nuclear-targeted 4E-BP1 is dephosphorylated, induces nuclear translocation of eIF4E, and alters mRNA translation
Exp Cell Res
2022
418(1):113246
PubMed ID: 35697076
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Oishi T, Ito M, Koizumi S, Horikawa M, Yamamoto T, Yamagishi S, Yamasaki T, Sameshima T, Suzuki T, Sugimura H, Namba H, Kurozumi K.
Efficacy of HSV-TK/GCV system suicide gene therapy using SHED expressing modified HSV-TK against lung cancer brain metastases.
Mol Ther Methods Clin Dev
2022
26:253-265
PubMed ID: 35892087
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20822
Deai M, Oya R, Saso N, Tanaka A, Uchida I, Miyake Y, Tachihara R, Otsugu M, Mine A, Sato K, Tomura H.
Ethylenediaminetetraacetic acid (EDTA) enhances cAMP production in human TDAG8-expressing cells.
Biochem Biophys Res Commun
2022
626:15-20
PubMed ID: 35964552
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Izumi A, Yamamoto K, Kawaguchi M, Yamashita F, Fukushima T, Kiwaki T, Tanaka H, Yamashita Y, Kataoka H.
Insufficiency of hepatocyte growth factor activator inhibitor-1 confers lymphatic invasion of tongue carcinoma cells
Cancer Sci
2022
113(6):2179-2193
PubMed ID: 35332604
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Kashio M, Masubuchi S, Tominaga M.
Protein kinase C (PKC)-mediated phosphorylation of TRPM2 Thr738 counteracts the effect of cytosolic Ca2+ and elevates the temperature threshold.
J Physiol
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PubMed ID: 36042566
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Zhou Z, Katoh Y, Nakayama K.
CEP19-RABL2-IFT-B axis controls BBSome-mediated ciliary GPCR export.
Mol Biol Cell
2022
PubMed ID: 36074075
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Nohara T, Ohno Y, Kihara A.
Impaired production of skin barrier lipid acylceramides and abnormal localization of PNPLA1 due to ichthyosis-causing mutations in PNPLA1.
J Dermatol Sci
2022
107(2):89-94
PubMed ID: 35970721
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Lyu X, Imai S, Yamano T, Hanayama R.
Preventing SARS-CoV-2 Infection Using Anti-spike Nanobody-IFN-β Conjugated Exosomes.
Pharm Res
2022
PubMed ID: 36163411
DOI: 10.1007/s11095-022-03400-0
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20873
Yamamura N, Mikkaichi T, Itokawa KI, Hoshi M, Damme K, Geigner S, Baumhauer C.
Mirogabalin, a novel α2δ ligand, is not a substrate of LAT1, but of PEPT1, PEPT2, OAT1, OAT3, OCT2, MATE1 and MATE2-K.
Xenobiotica
2022
1-42
PubMed ID: 36170033
DOI: 10.1080/00498254.2022.2129517
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20880
Kanadome T, Hayashi K, Seto Y, Eiraku M, Nakajima K, Nagai T, Matsuda T.
Development of intensiometric indicators for visualizing N-cadherin interaction across cells.
Commun Biol
2022
5(1):1065
PubMed ID: 36207396
DOI: 10.1038/s42003-022-04023-2
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20892
Mang D, Mayu K, Toyama T, Yamagishi T, Sato R.
BmGr4 responds to sucrose and glucose and expresses in tachykinin-related peptide-secreting enteroendocrine cells.
Insect Biochem Mol Biol
2022
103858
PubMed ID: 36244651
DOI: 10.1016/j.ibmb.2022.103858
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20906
Nakazato A, Mochizuki M, Shibuya-Takahashi R, Fujimori H, Fujii K, Saijoh S, Morita S, Yamazaki T, Imai T, Sato I, Satoh K, Yamaguchi K, Sugamura K, Yasuda J, Matsuura K, Shojaku H, Asada Y, Tamai K.
RELA is required for CD271 expression and stem-like characteristics in hypopharyngeal cancer.
Sci Rep
2022
12(1):17751
PubMed ID: 36273237
DOI: 10.1038/s41598-022-22736-6
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20912
Kotani N, Nakano T, Kuwahara R.
Host cell membrane proteins located near SARS-CoV-2 spike protein attachment sites are identified using proximity labeling and proteomic analysis.
J Biol Chem
2022
298(11):102500
PubMed ID: 36152751
DOI: 10.1016/j.jbc.2022.102500
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20914
Wang TW, Johmura Y, Suzuki N, Omori S, Migita T, Yamaguchi K, Hatakeyama S, Yamazaki S, Shimizu E, Imoto S, Furukawa Y, Yoshimura A, Nakanishi M.
Blocking PD-L1-PD-1 improves senescence surveillance and ageing phenotypes.
Nature
2022
PubMed ID: 36323784
DOI: 10.1038/s41586-022-05388-4
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20926
Akiyama M, Unoki T, Aoki H, Nishimura A, Shinkai Y, Warabi E, Nishiyama K, Furumoto Y, Anzai N, Akaike T, Nishida M, Kumagai Y.
Cystine-dependent antiporters buffer against excess intracellular reactive sulfur species-induced stress.
Redox Biol
2022
57:102514
PubMed ID: 36279630
DOI: 10.1016/j.redox.2022.102514
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17337
Sekine W, Takenaka-Uema A, Kamiki H, Ishida H, Matsugo H, Murakami S, Horimoto T.
Adaptation of the H7N2 Feline Influenza Virus to Human Respiratory Cell Culture
Viruses
2022
14(5):1091
PubMed ID: 35632832
DOI: 10.3390/v14051091
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20971
Tatsumi A, Hirakochi H, Inoue S, Tanaka Y, Furuno H, Ikeda M, Ishibashi S, Taguchi T, Yamamoto K, Onishi I, Sachs Z, Largaespada DA, Kitagawa M, Kurata M.
Identification of NRAS Downstream Genes with CRISPR Activation Screening.
Biology (Basel)
2022
11(11)
PubMed ID: 36358254
DOI: 10.3390/biology11111551
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20975
Moriyama H, Moriyama M, Ozawa T, Tsuruta D, Hayakawa T.
Differentiation of Human Adipose-Derived Mesenchymal Stromal/Stem Cells into Insulin-Producing Cells with A Single Tet-Off Lentiviral Vector System.
Cell J
2022
24(12):705-714
PubMed ID: 36527342
DOI: 10.22074/cellj.2022.557533.1063
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20998
Ozono T, Kimura Y, Suenaga T, Beck G, Jinno J, Aguirre C, Ikenaka K, Krainc D, Mochizuki H, Arase H.
Extracellular transportation of α-synuclein by HLA class II molecules.
Biochem Biophys Res Commun
2022
644:25-33
PubMed ID: 36621149
DOI: 10.1016/j.bbrc.2022.12.082
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21033
Takahashi TM, Hirano A, Kanda T, Saito VM, Ashitomi H, Tanaka KZ, Yokoshiki Y, Masuda K, Yanagisawa M, Vogt KE, Tokuda T, Sakurai T.
Optogenetic induction of hibernation-like state with modified human Opsin4 in mice.
Cell Rep Methods
2022
2(11):100336
PubMed ID: 36452866
DOI: 10.1016/j.crmeth.2022.100336
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21037
Takahashi M, Kobayashi T, Mizuma H, Yamauchi K, Okamoto S, Okamoto K, Ishida Y, Koike M, Watanabe M, Isa T, Hioki H.
Preferential arborization of dendrites and axons of parvalbumin- and somatostatin-positive GABAergic neurons within subregions of the mouse claustrum.
Neurosci Res
2022
PubMed ID: 36574563
DOI: 10.1016/j.neures.2022.11.008
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17361
Hirose Y, Shindo N, Mori M, Onitsuka S, Isogai H, Hamada R, Hiramoto T, Ochi J, Takahashi D, Ueda T, Caaveiro JMM, Yoshida Y, Ohdo S, Matsunaga N, Toba S, Sasaki M, Orba Y, Sawa H, Sato A, Kawanishi E, Ojida A.
Discovery of Chlorofluoroacetamide-Based Covalent Inhibitors for Severe Acute Respiratory Syndrome Coronavirus 2 3CL Protease
J Med Chem
2022
65(20):13852-13865
PubMed ID: 36229406
DOI: 10.1021/acs.jmedchem.2c01081
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21141
Suenaga T, Mori Y, Suzutani T, Arase H.
Siglec-7 mediates varicella-zoster virus infection by associating with glycoprotein B.
Biochem Biophys Res Commun
2022
607:67-72
PubMed ID: 35367830
DOI: 10.1016/j.bbrc.2022.03.060
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17694
Furuta T, Yamauchi K, Okamoto S, Takahashi M, Kakuta S, Ishida Y, Takenaka A, Yoshida A, Uchiyama Y, Koike M, Isa K, Isa T, Hioki H.
Multi-scale light microscopy/electron microscopy neuronal imaging from brain to synapse with a tissue clearing method, Sca l eSF
iScience
2021
25(1):103601
PubMed ID: 35106459
DOI: 10.1016/j.isci.2021.103601
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12798
Johmura Y, Yamanaka T, Omori S, Wang TW, Sugiura Y, Matsumoto M, Suzuki N, Kumamoto S, Yamaguchi K, Hatakeyama S, Takami T, Yamaguchi R, Shimizu E, Ikeda K, Okahashi N, Mikawa R, Suematsu M, Arita M, Sugimoto M, Nakayama KI, Furukawa Y, Imoto S, Nakanishi M.
Senolysis by glutaminolysis inhibition ameliorates various age-associated disorders
Science
2021
371(6526):265-270
PubMed ID: 33446552
DOI: 10.1126/science.abb5916
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13320
Matsumoto N, Sekiya M, Fujimoto Y, Haga S, Sun-Wada GH, Wada Y, Nakanishi-Matsui M.
Functional complementation of V-ATPase a subunit isoforms in osteoclasts.
J Biochem
2021
169(4):459-466
PubMed ID: 33135054
DOI: 10.1093/jb/mvaa118
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13345
Daifu T, Mikami M, Hiramatsu H, Iwai A, Umeda K, Noura M, Kubota H, Masuda T, Furuichi K, Takasaki S, Noguchi Y, Morita K, Bando T, Hirata M, Kataoka TR, Nakahata T, Kuwahara Y, Iehara T, Hosoi H, Takita J, Sugiyama H, Adachi S, Kamikubo Y.
Suppression of malignant rhabdoid tumors through Chb-M'-mediated RUNX1 inhibition.
Pediatr Blood Cancer
2021
PubMed ID: 33180377
DOI: 10.1002/pbc.28789
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13351
Matsumoto Y, Kishida K, Matsumoto M, Matsuoka S, Kohyama M, Suenaga T, Arase H.
A TCR-like antibody against a proinsulin-containing fusion peptide ameliorates type 1 diabetes in NOD mice.
Biochem Biophys Res Commun
2021
PubMed ID: 33208230
DOI: 10.1016/j.bbrc.2020.11.019
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13463
Shota Someya et al
Tryptophan Metabolism Regulates Proliferative Capacity of Human Pluripotent Stem Cells
iScienc
2021
24
PubMed ID: 33615198
DOI: 10.1016/j.isci.2021.102090
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20008
Umaba R, Kitanishi T, Mizuseki K.
Monosynaptic connection from the subiculum to medial mammillary nucleus neurons projecting to the anterior thalamus and Gudden's ventral tegmental nucleus.
Neurosci Res
2021
PubMed ID: 33476683
DOI: 10.1016/j.neures.2021.01.006
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20053
Takafuji S, Mori T, Nishimura N, Yamamoto N, Uemura S, Nozu K, Terui K, Toki T, Ito E, Muramatsu H, Takahashi Y, Matsuo M, Yamamura T, Iijima K.
Usefulness of functional splicing analysis to confirm precise disease pathogenesis in Diamond-Blackfan anemia caused by intronic variants in RPS19.
Pediatr Hematol Oncol
2021
1-16
PubMed ID: 33622161
DOI: 10.1080/08880018.2021.1887984
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20060
Nishiike Y, Miyazoe D, Togawa R, Yokoyama K, Nakasone K, Miyata M, Kikuchi Y, Kamei Y, Todo T, Ishikawa-Fujiwara T, Ohno K, Usami T, Nagahama Y, Okubo K.
Estrogen receptor 2b is the major determinant of sex-typical mating behavior and sexual preference in medaka.
Curr Biol
2021
PubMed ID: 33639108
DOI: 10.1016/j.cub.2021.01.089
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13513
Takahashi Y, Wake H, Sakaguchi M, Yoshii Y, Teshigawara K, Wang D, Nishibori M.
Histidine-Rich Glycoprotein Stimulates Human Neutrophil Phagocytosis and Prolongs Survival through CLEC1A
J Immunol
2021
206(4):737-750
PubMed ID: 33452125
DOI: 10.4049/jimmunol.2000817
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20067
Aizawa N, Fujimori Y, Nakanishi O, Hayashi T, Goi Y, Kobayashi JI, Fujita T.
Efficacy of the combination of KPR-5714, a novel transient receptor potential melastatin 8 (TRPM8) antagonist, and β3-adrenoceptor agonist or anticholinergic agent on bladder dysfunction in rats with bladder overactivity.
Eur J Pharmacol
2021
173995
PubMed ID: 33675781
DOI: 10.1016/j.ejphar.2021.173995
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20068
Nakamura R, Oyama T, Inokuchi M, Ishikawa S, Hirata M, Kawashima H, Ikeda H, Dobashi Y, Ooi A.
Neural EGFL like 2 expressed in myoepithelial cells and suppressed breast cancer cell migration.
Pathol Int
2021
PubMed ID: 33657249
DOI: 10.1111/pin.13087
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13640
Fujita K, Koide N, Somiya M, Kuroda S, Hinuma S.
A regulatory role of scavenger receptor class B type 1 in endocytosis and lipid droplet formation induced by liposomes containing phosphatidylethanolamine in HEK293T cells
Biochim Biophys Acta Mol Cell Res
2021
1868(1):118859
PubMed ID: 32956759
DOI: 10.1016/j.bbamcr.2020.118859
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20083
Hama K, Fujiwara Y, Hayama T, Ozawa T, Nozawa K, Matsuda K, Hashiguchi Y, Yokoyama K.
Very long-chain fatty acids are accumulated in triacylglycerol and nonesterified forms in colorectal cancer tissues.
Sci Rep
2021
11(1):6163
PubMed ID: 33731797
DOI: 10.1038/s41598-021-85603-w
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20103
McKee HK, Kajiwara C, Yamaguchi T, Ishii Y, Shimizu N, Ohara A, Tateda K.
Clostridioides difficile toxins enhanced the in vitro production of CXC chemokine ligand 2 and tumor necrosis factor-α via Toll-like receptors in macrophages.
J Med Microbiol
2021
70(4)
PubMed ID: 33830910
DOI: 10.1099/jmm.0.001342
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13898
Takuma Kitanishi, Ryoko Umaba, Kenji Mizuseki
Robust information routing by dorsal subiculum neurons
Sci Adv
2021
7(11):eabf1913
PubMed ID: 33692111
DOI: 10.1126/sciadv.abf1913
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13913
Rai D, Akagi T, Shimohata A, Ishii T, Gangi M, Maruyama T, Wada-Kiyama Y, Ogiwara I, Kaneda M.
Involvement of the C-terminal domain in cell surface localization and G-protein coupling of mGluR6
J Neurochem
2021
158(4):837-848
PubMed ID: 33067823
DOI: 10.1111/jnc.15217
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20114
Ojiro I, Nishio H, Yamazaki-Ito T, Nakano S, Ito S, Toyohara Y, Hiramoto T, Terada Y, Ito K.
Trp-Trp acts as a multi-functional blocker for human bitter taste receptors, hTAS2R14, hTAS2R16, hTAS2R43, and hTAS2R46.
Biosci Biotechnol Biochem
2021
PubMed ID: 33844825
DOI: 10.1093/bbb/zbab061
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20138
Nagumo Y, Kandori S, Tanuma K, Nitta S, Chihara I, Shiga M, Hoshi A, Negoro H, Kojima T, Mathis BJ, Funakoshi Y, Nishiyama H.
PLD1 promotes tumor invasion by regulation of MMP-13 expression via NF-κB signaling in bladder cancer.
Cancer Lett
2021
511:15-25
PubMed ID: 33945837
DOI: 10.1016/j.canlet.2021.04.014
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20147
Kariya Y, Oyama M, Suzuki T, Kariya Y.
αvβ3 Integrin induces partial EMT independent of TGF-β signaling.
Commun Biol
2021
4(1):490
PubMed ID: 33883697
DOI: 10.1038/s42003-021-02003-6
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14182
Somiya M, Kuroda S.
Real-Time Luminescence Assay for Cytoplasmic Cargo Delivery of Extracellular Vesicles
Anal Chem
2021
93(13):5612-5620
PubMed ID: 33759512
DOI: 10.1021/acs.analchem.1c00339
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20150
Takeshita M, Suzuki K, Nakazawa M, Kamata H, Ishii M, Oyamada Y, Oshima H, Takeuchi T.
Antigen-driven autoantibody production in lungs of interstitial lung disease with autoimmune disease.
J Autoimmun
2021
121:102661
PubMed ID: 34034155
DOI: 10.1016/j.jaut.2021.102661
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20155
Sahoo PR, Kowada T, Mizukami S.
Long-Term Mg2+ Imaging in Live Cells with a Targetable Fluorescent Probe.
Methods Mol Biol
2021
2274:237-243
PubMed ID: 34050476
DOI: 10.1007/978-1-0716-1258-3_20
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20157
Matsui H, Ito J, Matsui N, Uechi T, Onodera O, Kakita A.
Cytosolic dsDNA of mitochondrial origin induces cytotoxicity and neurodegeneration in cellular and zebrafish models of Parkinson's disease.
Nat Commun
2021
12(1):3101
PubMed ID: 34035300
DOI: 10.1038/s41467-021-23452-x
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20158
Osakabe K, Wada N, Murakami E, Miyashita N, Osakabe Y.
Genome editing in mammalian cells using the CRISPR type I-D nuclease.
Nucleic Acids Res
2021
PubMed ID: 34076237
DOI: 10.1093/nar/gkab348
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20165
Kobayashi JI, Hirasawa H, Fujimori Y, Nakanishi O, Kamada N, Ikeda T, Yamamoto A, Kanbe H.
Identification of N-acyl-N-indanyl-α-phenylglycinamides as selective TRPM8 antagonists designed to mitigate the risk of adverse effects.
Bioorg Med Chem
2021
30:115903
PubMed ID: 33333445
DOI: 10.1016/j.bmc.2020.115903
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14478
Yamanaka D, Shoda M, Matsubara T, Ishibashi KI, Motoi A, Motoi R, Motoi M, Ohno N, Adachi Y.
Open-Label Study of the Influence of Food Containing the Royal Sun Mushroom, Agaricus brasiliensis KA21 (Agaricomycetes), on β-Glucan-Specific Antibody Production in Healthy Human Volunteers
Int J Med Mushrooms
2021
23(2):13-28
PubMed ID: 33639078
DOI: 10.1615/IntJMedMushrooms.2020037471
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20199
Tomita T, Kato M, Mishima T, Matsunaga Y, Sanjo H, Ito KI, Minagawa K, Matsui T, Oikawa H, Takahashi S, Takao T, Iwai N, Mino T, Takeuchi O, Maru Y, Hiratsuka S.
Extracellular mRNA transported to the nucleus exerts translation-independent function.
Nat Commun
2021
12(1):3655
PubMed ID: 34135341
DOI: 10.1038/s41467-021-23969-1
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20200
Kuwabara S, Tanimoto Y, Okutani M, Jie M, Haseda Y, Kinugasa-Katayama Y, Aoshi T.
Microfluidics sorting enables the isolation of an intact cellular pair complex of CD8+ T cells and antigen-presenting cells in a cognate antigen recognition-dependent manner.
PLoS One
2021
16(6):e0252666
PubMed ID: 34125844
DOI: 10.1371/journal.pone.0252666
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20216
Niinae T, Imami K, Sugiyama N, Ishihama Y.
Identification of Endogenous Kinase Substrates by Proximity Labeling Combined with Kinase Perturbation and Phosphorylation Motifs.
Mol Cell Proteomics
2021
100119
PubMed ID: 34186244
DOI: 10.1016/j.mcpro.2021.100119
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14782
Uemura K, Sasaki M, Sanaki T, Toba S, Takahashi Y, Orba Y, Hall WW, Maenaka K, Sawa H, Sato A.
MRC5 cells engineered to express ACE2 serve as a model system for the discovery of antivirals targeting SARS-CoV-2
Sci Rep
2021
11(1):5376
PubMed ID: 33686154
DOI: 10.1038/s41598-021-84882-7
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14827
iu Y, Soh WT, Kishikawa JI, Hirose M, Nakayama EE, Li S, Sasai M, Suzuki T, Tada A, Arakawa A, Matsuoka S, Akamatsu K, Matsuda M, Ono C, Torii S, Kishida K, Jin H, Nakai W, Arase N, Nakagawa A, Matsumoto M, Nakazaki Y, Shindo Y, Kohyama M, Tomii K, Ohmura K, Ohshima S, Okamoto T, Yamamoto M, Nakagami H, Matsuura Y, Nakagawa A, Kato T, Okada M, Standley DM, Shioda T, Arase H.
An infectivity-enhancing site on the SARS-CoV-2 spike protein targeted by antibodies
Cell
2021
184(13):3452-3466.e18
PubMed ID: 34139176
DOI: 10.1016/j.cell.2021.05.032
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20233
Koshizuka T, Kondo H, Kato H, Takahashi K.
Human cytomegalovirus UL42 protein inhibits the degradation of glycoprotein B through inhibition of Nedd4 family ubiquitin E3 ligases.
Microbiol Immunol
2021
PubMed ID: 34260096
DOI: 10.1111/1348-0421.12932
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20240
Kaku T, Sugiura K, Entani T, Osabe K, Nagai T.
Enhanced brightness of bacterial luciferase by bioluminescence resonance energy transfer.
Sci Rep
2021
11(1):14994
PubMed ID: 34294849
DOI: 10.1038/s41598-021-94551-4
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14939
Shuji Hinuma, Kazuyo Fujita, Shun’ichi Kuroda
Binding of Nanoparticles Harboring Recombinant Large Surface Protein of Hepatitis B Virus to Scavenger Receptor Class B Type 1
Viruses
2021
13:1334
PubMed ID: 34372540
DOI: 10.3390/v13071334
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20244
Yoshioka K, Obara K, Oikawa S, Uemura K, Yamaguchi A, Fujisawa K, Hanazawa H, Fujiwara M, Endoh T, Suzuki T, Regadera MD, Ito D, Ou G, Xu K, Tanaka Y.
Docosahexaenoic acid inhibits U46619- and prostaglandin F2α-induced pig coronary and basilar artery contractions by inhibiting prostanoid TP receptors.
Eur J Pharmacol
2021
174371
PubMed ID: 34329614
DOI: 10.1016/j.ejphar.2021.174371
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20272
Ma Y, Yoshida T, Matoba K, Kida K, Shintani R, Piao Y, Jin J, Nishino T, Hanayama R.
Identification of small compounds regulating the secretion of extracellular vesicles via a TIM4-affinity ELISA.
Sci Rep
2021
11(1):13471
PubMed ID: 34188113
DOI: 10.1038/s41598-021-92860-2
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15168
Hangai S, Kawamura T, Kimura Y, Chang CY, Hibino S, Yamamoto D, Nakai Y, Tateishi R, Oshima M, Oshima H, Kodama T, Moriya K, Koike K, Yanai H, Taniguchi T.
Orchestration of myeloid-derived suppressor cells in the tumor microenvironment by ubiquitous cellular protein TCTP released by tumor cells
Nat Immunol
2021
22(8):947-957
PubMed ID: 34239121
DOI: 10.1038/s41590-021-00967-5
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20282
Nakanishi E, Uemura N, Akiyama H, Kinoshita M, Masanori S, Taruno Y, Yamakado H, Matsuzawa SI, Takeda S, Hirabayashi Y, Takahashi R.
Impact of Gba2 on neuronopathic Gaucher's disease and α-synuclein accumulation in medaka (Oryzias latipes).
Mol Brain
2021
14(1):80
PubMed ID: 33971917
DOI: 10.1186/s13041-021-00790-x
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20283
Sakoguchi A, Saito F, Hirayasu K, Shida K, Matsuoka S, Itagaki S, Nakai W, Kohyama M, Suenaga T, Iwanaga S, Horii T, Arase H.
Plasmodium falciparum RIFIN is a novel ligand for inhibitory immune receptor LILRB2.
Biochem Biophys Res Commun
2021
548:167-173
PubMed ID: 33647792
DOI: 10.1016/j.bbrc.2021.02.033
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20298
Nagano C, Takaoka Y, Kamei K, Hamada R, Ichikawa D, Tanaka K, Aoto Y, Ishiko S, Rossanti R, Sakakibara N, Okada E, Horinouchi T, Yamamura T, Tsuji Y, Noguchi Y, Ishimori S, Nagase H, Ninchoji T, Iijima K, Nozu K.
Genotype-Phenotype Correlation in WT1 Exon 8 to 9 Missense Variants.
Kidney Int Rep
2021
6(8):2114-2121
PubMed ID: 34386660
DOI: 10.1016/j.ekir.2021.05.009
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20322
Fujisawa S, Qiu H, Nozaki S, Chiba S, Katoh Y, Nakayama K.
ARL3 and ARL13B GTPases participate in distinct steps of INPP5E targeting to the ciliary membrane.
Biol Open
2021
PubMed ID: 34447983
DOI: 10.1242/bio.058843
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15284
Yoshiko Iizuka, Kinuko Inomata, Risako Nohara, Akimitsu Miyawaki and Yoshifumi Watanabe
Activation of intracellular antioxidant master gene Nrf2 by the extracts of Garcinia subelliptica, Ocimum gratissimum L., and Plectranthus ornatus
International Journal of Herbal Medicine
2021
9(3):54-60
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15524
Fukasawa K, Kadota T, Horie T, Tokumura K, Terada R, Kitaguchi Y, Park G, Ochiai S, Iwahashi S, Okayama Y, Hiraiwa M, Yamada T, Iezaki T, Kaneda K, Yamamoto M, Kitao T, Shirahase H, Hazawa M, Wong RW, Todo T, Hirao A, Hinoi E.
CDK8 maintains stemness and tumorigenicity of glioma stem cells by regulating the c-MYC pathway
Oncogene
2021
40(15):2803-2815
PubMed ID: 33727660
DOI: 10.1038/s41388-021-01745-1
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20354
Noguchi T, Nakamura K, Satoda Y, Katoh Y, Nakayama K.
CCRK/CDK20 regulates ciliary retrograde protein trafficking via interacting with BROMI/TBC1D32.
PLoS One
2021
16(10):e0258497
PubMed ID: 34624068
DOI: 10.1371/journal.pone.0258497
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20356
Yasumura M, Hagiwara A, Hida Y, Ohtsuka T.
Planar cell polarity protein Vangl2 and its interacting protein Ap2m1 regulate dendritic branching in cortical neurons.
Genes Cells
2021
PubMed ID: 34626136
DOI: 10.1111/gtc.12899
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20367
Kariya Y, Oyama M, Kariya Y, Hashimoto Y.
Phosphorylated Osteopontin Secreted from Cancer Cells Induces Cancer Cell Motility.
Biomolecules
2021
11(9)
PubMed ID: 34572536
DOI: 10.3390/biom11091323
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20403
Yaguchi A, Oshikawa M, Watanabe G, Hiramatsu H, Uchida N, Hara C, Kaneko N, Sawamoto K, Muraoka T, Ajioka I.
Efficient protein incorporation and release by a jigsaw-shaped self-assembling peptide hydrogel for injured brain regeneration.
Nat Commun
2021
12(1):6623
PubMed ID: 34799548
DOI: 10.1038/s41467-021-26896-3
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20440
Kanadome T, Hoshino N, Nagai T, Matsuda T, Yagi T.
Development of FRET-based indicators for visualizing homophilic trans interaction of a clustered protocadherin.
Sci Rep
2021
11(1):22237
PubMed ID: 34782670
DOI: 10.1038/s41598-021-01481-2
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15879
Uemura K, Nobori H, Sato A, Sanaki T, Toba S, Sasaki M, Murai A, Saito-Tarashima N, Minakawa N, Orba Y, Kariwa H, Hall WW, Sawa H, Matsuda A, Maenaka K.
5-Hydroxymethyltubercidin exhibits potent antiviral activity against flaviviruses and coronaviruses, including SARS-CoV-2
iScience
2021
24(10):103120
PubMed ID: 34541466
DOI: 10.1016/j.isci.2021.103120
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Treatment of Retinoblastoma 1-Intact Hepatocellular Carcinoma With Cyclin-Dependent Kinase 4/6 Inhibitor Combination Therapy
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PACAP-PAC1 Signaling Regulates Serotonin 2A Receptor Internalization
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Front Endocrinol (Lausanne)
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iPSC-Derived Neoantigen-Specific CTL Therapy for Ewing Sarcoma
Cancer Immunol Res
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Discovery of a transdermally deliverable pentapeptide for activating AdipoR1 to promote hair growth
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Cytotechnology
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V-ATPase a3 Isoform Mutations Identified in Osteopetrosis Patients Abolish Its Expression and Disrupt Osteoclast Function
Exp Cell Res
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17β-Hydroxysteroid Dehydrogenase Type 12a Responsible for Testicular 11-ketotestosterone Synthesis in the Japanese Eel, Anguilla Japonica
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HTLV-1 Induces T Cell Malignancy and Inflammation by Viral Antisense Factor-Mediated Modulation of the Cytokine Signaling
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Novel Nile tilapia Neu1 sialidases: Molecular cloning and biochemical characterization of the sialidases Neu1a and Neu1b.
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Kampo medicines, Rokumigan, Hachimijiogan, and Goshajinkigan, significantly inhibit glucagon-induced CREB activation.
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The enantiomer pair of 24S- and 24R-hydroxycholesterol differentially alter activity of large-conductance Ca 2+ -dependent K + (slo1 BK) channel
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Polarization-sensitive optical coherence tomography for estimating relative melanin content of autologous induced stem-cell derived retinal pigment epithelium.
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Homeostatic and pathogenic roles of GM3 ganglioside molecular species in TLR4 signaling in obesity.
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AirID, a novel proximity biotinylation enzyme, for analysis of protein-protein interactions.
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Neuroplastinβ-mediated upregulation of solute carrier family 22 member 18 antisense (SLC22A18AS) plays a crucial role in the epithelial-mesenchymal transition, leading to lung cancer cells' enhanced motility.
Biochem Biophys Rep
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Park M, Miyoshi C, Fujiyama T, Kakizaki M, Ikkyu A, Honda T, Choi J, Asano F, Mizuno S, Takahashi S, Yanagisawa M, Funato H.
Loss of the conserved PKA sites of SIK1 and SIK2 increases sleep need.
Sci Rep
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Horinouchi T, Yamamura T, Minamikawa S, Nagano C, Sakakibara N, Nakanishi K, Shima Y, Morisada N, Ishiko S, Aoto Y, Nagase H, Takeda H, Rossanti R, Ishimori S, Kaito H, Matsuo M, Iijima K, Nozu K.
Pathogenic evaluation of synonymous COL4A5 variants in X-linked Alport syndrome using a minigene assay.
Mol Genet Genomic Med
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Ito F, Yanatori I, Maeda Y, Nimura K, Ito S, Hirayama T, Nagasawa H, Kohyama N, Okazaki Y, Akatsuka S, Toyokuni S.
Asbestos conceives Fe(II)-dependent mutagenic stromal milieu through ceaseless macrophage ferroptosis and β-catenin induction in mesothelium.
Redox Biol
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Yamashita J, Takeuchi A, Hosono K, Fleming T, Nagahama Y, Okubo K.
Male-predominant galanin mediates androgen-dependent aggressive chases in medaka.
Elife
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Genome editing with the donor plasmid equipped with synthetic crRNA-target sequence.
Sci Rep
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Huetter J, Gritzan U, Gutcher I, Doecke WD, Luetke-Eversloh MV, Golfier S, Roider HG, Frisk AL, Hunter J, Pow A, Drake A, Levine Z, Levy O, Azulay M, Barbiro I, Cojocaru G, Vaknin I, Kreft B, Roese L.
Characterization of BAY 1905254, an Immune Checkpoint Inhibitor Targeting the Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2).
Cancer Immunol Res
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Kakizawa S, Kishimoto Y, Yamamoto S, Onga K, Yasuda K, Miyamoto Y, Watanabe M, Sakai R, Mori N.
Functional maintenance of calcium store by ShcB adaptor protein in cerebellar Purkinje cells.
Sci Rep
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Ago Y, Otsuka H, Sasai H, Abdelkreem E, Nakama M, Aoyama Y, Matsumoto H, Fujiki R, Ohara O, Akiyama K, Fukui K, Watanabe Y, Nakajima Y, Ohnishi H, Ito T, Fukao T.
Japanese patients with mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase deficiency: In vitro functional analysis of five novel HMGCS2 mutations.
Exp Ther Med
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Kinoshita N, Huang AJY, McHugh TJ, Miyawaki A, Shimogori T.
Diffusible GRAPHIC to visualize morphology of cells after specific cell-cell contact.
Sci Rep
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Kitao T, Taguchi K, Seto S, Arasaki K, Ando H, Nagai H, Kubori T.
Legionella Manipulates Non-canonical SNARE Pairing Using a Bacterial Deubiquitinase.
Cell Rep
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Arai Y, Kawashita N, Elgendy EM, Ibrahim MS, Daidoji T, Ono T, Takagi T, Nakaya T, Matsumoto K, Watanabe Y.
PA Mutations Inherited during Viral Evolution Act Cooperatively To Increase Replication of Contemporary H5N1 Influenza Virus with an Expanded Host Range.
J Virol
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Okamura M, Shizu R, Abe T, Kodama S, Hosaka T, Sasaki T, Yoshinari K.
PXR Functionally Interacts with NF-κB and AP-1 to Downregulate the Inflammation-Induced Expression of Chemokine CXCL2 in Mice.
Cells
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Kato M, Onoyama I, Kawakami M, Yoshida S, Kawamura K, Kodama K, Hori E, Cui L, Matsumura Y, Yagi H, Asanoma K, Yahata H, Itakura A, Takeda S, Kato K.
Downregulation of 5-hydroxymethylcytosine is associated with the progression of cervical intraepithelial neoplasia.
PLoS One
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Yamazaki T, Takahashi C, Taniguchi Y, Narukawa M, Misaka T, Ano Y.
Bitter taste receptor activation by hop-derived bitter components induces gastrointestinal hormone production in enteroendocrine cells.
Biochem Biophys Res Commun
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PubMed ID: 33160623
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Osakabe K, Wada N, Miyaji T, Murakami E, Marui K, Ueta R, Hashimoto R, Abe-Hara C, Kong B, Yano K, Osakabe Y.
Genome editing in plants using CRISPR type I-D nuclease.
Commun Biol
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Shoji S, Hanada K, Takahashi M, Watanabe K, Yonemochi M, Tomabechi Y, Shirouzu M.
The NF-κB regulator IκBβ exhibits different molecular interactivity and phosphorylation status from IκBα in an IKK2-catalysed reaction
FEBS Lett
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Development of a Single Construct System for Site-Directed RNA Editing Using MS2-ADAR
Int J Mol Sci
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Harada M, Nghia VT, Nakao A, Tanigaki R, Fukuoka N, Nishida A, Kataoka T.
Eomesodermin promotes interaction of RelA and NFATc2 with the Ifng promoter and multiple conserved noncoding sequences across the Ifng locus in mouse lymphoma BW5147 cells
Immunol Lett
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Suzuki T, Morimoto N, Akaike A, Osakada F.
Multiplex Neural Circuit Tracing With G-Deleted Rabies Viral Vectors
Front Neural Circuits
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Overexpression of neural miRNAs miR-9/9* and miR-124 suppresses differentiation to Müller glia and promotes differentiation to neurons in mouse retina in vivo
Genes Cells
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Cooperative activation of the human herpesvirus 6B U79/80 early gene promoter by immediate-early proteins IE1B and IE2B
Microbiol Immunol
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Species-Dependent Enhancement of Ovarian Cancer G Protein-Coupled Receptor 1 Activation by Ogerin
Zoolog Sci
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TGF-β-Induced TMEPAI Attenuates the Response of Triple-Negative Breast Cancer Cells to Doxorubicin and Paclitaxel
J Exp Pharmacol
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N-terminal [Glu] 3 moiety of γ-glutamyl peptides contributes largely to the activation of human calcium-sensing receptor, a kokumi receptor
Biosci Biotechnol Biochem
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GPRC5A facilitates cell proliferation through cell cycle regulation and correlates with bone metastasis in prostate cancer
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Sci Rep
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Establishment of a Reverse Genetics System for Influenza D Virus
J Virol
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Overexpression of RUNX3 Represses RUNX1 to Drive Transformation of Myelodysplastic Syndrome
Cancer Res
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Lysosome-Associated Membrane Proteins Support the Furin-Mediated Processing of the Mumps Virus Fusion Protein
J Virol
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Effective RNA Knockdown Using CRISPR-Cas13a and Molecular Targeting of the EML4-ALK Transcript in H3122 Lung Cancer Cells
Effective RNA Knockdown Using CRISPR-Cas13a and Molecular Targeting of the EML4-ALK Transcript in H3122 Lung Cancer Cells
Int J Mol Sci
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An Antiviral Drug Screening Platform with a FRET Biosensor for Measurement of Arenavirus Z Assembly
Cell Struct Funct
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Red-kerneled rice proanthocyanidin inhibits arachidonate 5-lipoxygenase and decreases psoriasis-like skin inflammation
Arch Biochem Biophys
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Synthesis of C12-Keto Saxitoxin Derivatives with Unusual Inhibitory Activity Against Voltage-Gated Sodium Channels
Chemistry
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Increased luminescence of the GloSensor cAMP assay in LβT2 cells does not correlate with cAMP accumulation under low pH conditions
J Reprod Dev
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FASEB J.
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The role of E2F8 in the human placenta.
Mol Med Rep
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Globo-series glycosphingolipids enhance Toll-like receptor 4-mediated inflammation and play a pathophysiological role in diabetic nephropathy.
Glycobiology
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Arai Y, Ibrahim MS, Elgendy EM, Daidoji T, Ono T, Suzuki Y, Nakaya T, Matsumoto K, Watanabe Y.
Genetic Compatibility of Reassortants between Avian H5N1 and H9N2 Influenza Viruses with Higher Pathogenicity in Mammals.
J. Virol.
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Mol. Cell. Biochem.
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J. Biol. Chem.
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Arid3a regulates nephric tubule regeneration via evolutionarily conserved regeneration signal-response enhancers.
Elife
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Kataoka K, Miyoshi H, Sakata S, Dobashi A, Couronné L, Kogure Y, Sato Y, Nishida K, Gion Y, Shiraishi Y, Tanaka H, Chiba K, Watatani Y, Kakiuchi N, Shiozawa Y, Yoshizato T, Yoshida K, Makishima H, Sanada M, Onozawa M, Teshima T, Yoshiki Y, Ishida T, Suzuki K, Shimada K, Tomita A, Kato M, Ota Y, Izutsu K, Demachi-Okamura A, Akatsuka Y, Miyano S, Yoshino T, Gaulard P, Hermine O, Takeuchi K, Ohshima K, Ogawa S.
Frequent structural variations involving programmed death ligands in Epstein-Barr virus-associated lymphomas.
Leukemia
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Matsumoto N, Nakanishi-Matsui M.
Proton pumping V-ATPase inhibitor bafilomycin A1 affects Rab7 lysosomal localization and abolishes anterograde trafficking of osteoclast secretory lysosomes.
Biochem. Biophys. Res. Commun.
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Int. Immunol.
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Ishibashi D, Homma T, Nakagaki T, Fuse T, Sano K, Satoh K, Mori T, Atarashi R, Nishida N.
Type I interferon protects neurons from prions in in vivo models.
Brain
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Yorifuji H, Arase N, Kohyama M, Hirano T, Suenaga T, Kumanogoh A, Arase H.
Transport of cellular misfolded proteins to the cell surface by HLA-B27 free heavy chain.
Biochem. Biophys. Res. Commun.
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Sarkar B, Nishikata I, Nakahata S, Ichikawa T, Shiraga T, Saha HR, Fujii M, Tanaka Y, Shimoda K, Morishita K.
Degradation of p47 by autophagy contributes to CADM1 overexpression in ATLL cells through the activation of NF-κB.
Sci Rep
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Chen Y, Sumardika IW, Tomonobu N, Winarsa Ruma IM, Kinoshita R, Kondo E, Inoue Y, Sato H, Yamauchi A, Murata H, Yamamoto KI, Tomida S, Shien K, Yamamoto H, Soh J, Liu M, Futami J, Sasai K, Katayama H, Kubo M, Putranto EW, Hibino T, Sun B, Nishibori M, Toyooka S, Sakaguchi M.
Melanoma cell adhesion molecule is the driving force behind the dissemination of melanoma upon S100A8/A9 binding in the original skin lesion.
Cancer Lett.
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TRPM4 and TRPM5 Channels Share Crucial Amino Acid Residues for Ca2+ Sensitivity but Not Significance of PI(4,5)P2.
Int J Mol Sci
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Yokoyama T, Machida K, Iwasaki W, Shigeta T, Nishimoto M, Takahashi M, Sakamoto A, Yonemochi M, Harada Y, Shigematsu H, Shirouzu M, Tadakuma H, Imataka H, Ito T.
HCV IRES Captures an Actively Translating 80S Ribosome.
Mol Cell
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Int. J. Oncol.
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Int. J. Oncol.
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The human Bcl-2 family member Bcl-rambo and voltage-dependent anion channels manifest a genetic interaction in Drosophila and cooperatively promote the activation of effector caspases in human cultured cells.
Exp. Cell Res.
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Critical role of the MCAM-ETV4 axis triggered by extracellular S100A8/A9 in breast cancer aggressiveness.
Neoplasia
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Tanaka J, Mabuchi Y, Hata K, Yasuhara R, Takamatsu K, Kujiraoka S, Yukimori A, Takakura I, Sumimoto H, Fukada T, Azuma M, Akiyama H, Nishimura R, Shimane T, Mishima K.
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Exp. Cell Res.
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PB2 mutations arising during H9N2 influenza evolution in the Middle East confer enhanced replication and growth in mammals.
PLoS Pathog.
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Evolutionary and Functional Diversity of the 5' Untranslated Region of Enterovirus D68: Increased Activity of the Internal Ribosome Entry Site of Viral Strains during the 2010s.
Viruses
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Ishii J, Suzuki A, Kimura T, Tateyama M, Tanaka T, Yazawa T, Arimasu Y, Chen IS, Aoyama K, Kubo Y, Saitoh S, Mizuno H, Kamma H.
Congenital goitrous hypothyroidism is caused by dysfunction of the iodide transporter SLC26A7.
Commun Biol
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Identification of intermediate-sized deletions and inference of their impact on gene expression in a human population.
Genome Med
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Makino Y, Jensen NH, Yokota N, Rossner MJ, Akiyama H, Shirahige K, Okada Y.
Single cell RNA-sequencing identified Dec2 as a suppressive factor for spermatogonial differentiation by inhibiting Sohlh1 expression.
Sci Rep
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Yamanashi T, Maki M, Kojima K, Shibukawa A, Tsukamoto T, Chowdhury S, Yamanaka A, Takagi S, Sudo Y.
Quantitation of the neural silencing activity of anion channelrhodopsins in Caenorhabditis elegans and their applicability for long-term illumination.
Sci Rep
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Sequence-specific retrotransposition of 28S rDNA-specific LINE R2Ol in human cells.
RNA
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Kamiki H, Matsugo H, Ishida H, Kobayashi-Kitamura T, Sekine W, Takenaka-Uema A, Murakami S, Horimoto T.
Adaptation of H3N2 canine influenza virus to feline cell culture.
PLoS ONE
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Morita A, Aoshima K, Gulay KCM, Onishi S, Shibata Y, Yasui H, Kobayashi A, Kimura T.
High drug efflux pump capacity and low DNA damage response induce doxorubicin resistance in canine hemangiosarcoma cell lines.
Res. Vet. Sci.
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Protons Differentially Activate TDAG8 Homologs from Various Species.
Zoolog Sci
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Identification of sinensetin and nobiletin as major antitrypanosomal factors in a citrus cultivar.
Exp Parasitol
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Kazuyo Fujita, Masaharu Somiya, Shun'ichi Kuroda, Shuji Hinuma
Induction of Lipid Droplets in Non-Macrophage Cells as Well as Macrophages by Liposomes and Exosomes
Biochem Biophys Res Commun
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510(1):184-190
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Uchibori R, Teruya T, Ido H, Ohmine K, Sehara Y, Urabe M, Mizukami H, Mineno J, Ozawa K.
Functional Analysis of an Inducible Promoter Driven by Activation Signals from a Chimeric Antigen Receptor
Mol Ther Oncolytics
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Arisa Mitani, Takeshi Kobayashi, Yasuhito Hayashi, Natsuki Matsushita, Sachi Matsushita, Saori Nakao, Naoko Takahira, Atsushi Shiraishi, Yuichi Ohashi
Characterization of doxycycline-dependent inducible Simian Virus 40 large T antigen immortalized human conjunctival epithelial cell line
PLoS One
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14(9):e0222454
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Nobuyoshi Tajima, Liu Xiaoyan, Makoto Taniguchi, Nobuo Kato
24S-hydroxycholesterol alters activity of large-conductance Ca 2+-dependent K + (slo1 BK) channel through intercalation into plasma membrane
Biochim Biophys Acta Mol Cell Biol Lipids
2019
1864(10):1525-1535
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Shimizu K, Yamasaki S, Sakurai M, Yumoto N, Ikeda M, Mishima-Tsumagari C, Kukimoto-Niino M, Watanabe T, Kawamura M, Shirouzu M, Fujii SI.
Granzyme A Stimulates pDCs to Promote Adaptive Immunity via Induction of Type I IFN
Front Immunol
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Takahashi Y, Takahashi H, Stern PL, Kirita T, Tsuboi A.
Expression of Oncofetal Antigen 5T4 in Murine Taste Papillae
Front Cell Neurosci
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Ichikawa T, Nakahata S, Fujii M, Iha H, Shimoda K, Morishita K.
The regulation of NDRG2 expression during ATLL development after HTLV-1 infection
Biochim Biophys Acta Mol Basis Dis
2019
1865(10):2633-2646
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Okamura M, Shizu R, Hosaka T, Sasaki T, Yoshinari K.
Possible involvement of the competition for the transcriptional coactivator glucocorticoid receptor-interacting protein 1 in the inflammatory signal-dependent suppression of PXR-mediated CYP3A induction in vitro
Drug Metab Pharmacokinet
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34(4):272-279
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Mitsui Y, Tomonobu N, Watanabe M, Kinoshita R, Sumardika IW, Youyi C, Murata H, Yamamoto KI, Sadahira T, Rodrigo AGH, Takamatsu H, Araki K, Yamauchi A, Yamamura M, Fujiwara H, Inoue Y, Futami J, Saito K, Iioka H, Kondo E, Nishibori M, Toyooka S, Yamamoto Y, Nasu Y, Sakaguchi M.
Upregulation of Mobility in Pancreatic Cancer Cells by Secreted S100A11 Through Activation of Surrounding Fibroblasts
Oncol Res
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Quantitative analysis of the effects of nicotinamide phosphoribosyltransferase induction on the rates of NAD+ synthesis and breakdown in mammalian cells using stable isotope-labeling combined with mass spectrometry
PLoS One
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14(3):e0214000
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Liu Y, Wang Y, Wang F, Pan J, Xu J, Li J, Zhou C, Ding G, Wu Y, Liu X, Sheng J, Huang H.
Mechanism underlying the retarded nuclear translocation of androgen receptor splice variants
Sci China Life Sci
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62(2):257-267
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Yoh T, Hatano E, Kasai Y, Fuji H, Nishi K, Toriguchi K, Sueoka H, Ohno M, Seo S, Iwaisako K, Taura K, Yamaguchi R, Kurokawa M, Fujimoto J, Kimura T, Uemoto S, Nishi E.
Serum Nardilysin, a Surrogate Marker for Epithelial-Mesenchymal Transition, Predicts Prognosis of Intrahepatic Cholangiocarcinoma after Surgical Resection
Clin Cancer Res
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Maishi N, Kikuchi H, Sato M, Nagao-Kitamoto H, Annan DA, Baba S, Hojo T, Yanagiya M, Ohba Y, Ishii G, Masutomi K, Shinohara N, Hida Y, Hida K.
Development of Immortalized Human Tumor Endothelial Cells from Renal Cancer
Int J Mol Sci
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Sumardika IW, Chen Y, Tomonobu N, Kinoshita R, Ruma IMW, Sato H, Kondo E, Inoue Y, Yamauchi A, Murata H, Yamamoto KI, Tomida S, Shien K, Yamamoto H, Soh J, Futami J, Putranto EW, Hibino T, Nishibori M, Toyooka S, Sakaguchi M.
Neuroplastin-β mediates S100A8/A9-induced lung cancer disseminative progression
Mol Carcinog
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Horigome E, Fujieda M, Handa T, Katayama A, Ito M, Ichihara A, Tanaka D, Gombodorj N, Yoshiyama S, Yamane A, Yamada K, Horiguchi J, Shinozuka K, Oyama T, Nishiyama M, Rokudai S.
Mutant TP53 modulates metastasis of triple negative breast cancer through adenosine A2b receptor signaling
Oncotarget
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Nardilysin controls intestinal tumorigenesis through HDAC1/p53-dependent transcriptional regulation.
JCI Insight
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Herpesviruses possess conserved proteins for interaction with Nedd4 family ubiquitin E3 ligases.
Sci Rep
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Zool. Sci.
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Conserved and divergent functions of Pax6 underlie species-specific neurogenic patterns in the developing amniote brain.
Development
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A novel fiber-free technique for brain activity imaging in multiple freely behaving mice
SPIE BiOS
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Large-scale forward genetics screening identifies Trpa1 as a chemosensor for predator odor-evoked innate fear behaviors.
Nat Commun
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Arch. Biochem. Biophys.
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Eur. J. Pharmacol.
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Chem. Commun. (Camb.)
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Nat Commun
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Nat Commun
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BMC Vet. Res.
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Biochim Biophys Acta Gene Regul Mech
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Sci Rep
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Oncotarget
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Cell Chem Biol
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EMBO Mol Med
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Structural alteration of DNA induced by viral protein R of HIV-1 triggers the DNA damage response
Retrovirology
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Cell Rep
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Nature
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Blood Adv
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FEBS Open Bio
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An in vitro splicing assay reveals the pathogenicity of a novel intronic variant in ATP6V0A4 for autosomal recessive distal renal tubular acidosis.
BMC Nephrol
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A screening system to identify transcription factors that induce binding site-directed DNA demethylation.
Epigenetics Chromatin
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MAFB prevents excess inflammation after ischemic stroke by accelerating clearance of damage signals through MSR1.
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Loss of Parkinson's disease-associated protein CHCHD2 affects mitochondrial crista structure and destabilizes cytochrome c.
Nat Commun
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Biosci Biotechnol Biochem
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A Single Vector Platform for High-Level Gene Transduction of Central Neurons: Adeno-Associated Virus Vector Equipped With the Tet-Off System
PLoS One
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Shigenori Inagaki, Hidekazu Tsutsui, Kazushi Suzuki, Masakazu Agetsuma, Yoshiyuki Arai, Yuka Jinno, Guirong Bai, Matthew J Daniels, Yasushi Okamura, Tomoki Matsuda, Takeharu Nagai
Genetically encoded bioluminescent voltage indicator for multi-purpose use in wide range of bioimaging
Sci Rep
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Establishment of highly metastatic KRAS mutant lung cancer cell sublines in long-term three-dimensional low attachment cultures
PLoS Onec
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A chromosome 16p13.11 microduplication causes hyperactivity through dysregulation of miR-484/protocadherin-19 signaling
Mol Psychiatry
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Sustained Activation of the Unfolded Protein Response Induces Cell Death in Fuchs' Endothelial Corneal Dystrophy
Invest Ophthalmol Vis Sci
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AlphaScreen-based homogeneous assay using a pair of 25-residue artificial proteins for high-throughput analysis of non-native IgG
Sci Rep
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Peptides
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Development of a double-stranded siRNA labelling method by using 99m Tc and single photon emission computed tomography imaging
J Drug Target
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Differential binding of tetrodotoxin and its derivatives to voltage-sensitive sodium channel subtypes (Na v 1.1 to Na v 1.7)
Br J Pharmacol
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Reprogramming Antagonizes the Oncogenicity of HOXA13-Long Noncoding RNA HOTTIP Axis in Gastric Cancer Cells
Stem Cells
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Towards water-free biobanks: long-term dry-preservation at room temperature of desiccation-sensitive enzyme luciferase in air-dried insect cells
Sci Rep
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Synthesis and optimization of novel α-phenylglycinamides as selective TRPM8 antagonists
Bioorg Med Chem
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Identification of polymerase gene mutations that affect viral replication in H5N1 influenza viruses isolated from pigeons
J Gen Virol
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bioRxiv
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Dual control of pcdh8l/PCNS expression and function in Xenopus laevis neural crest cells by adam13/33 via the transcription factors tfap2α and arid3a
Elife
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Nat Commun
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Nature
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Nat Commun
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Nature
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