| 利用者成果(英) |
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21666
Zhang Z, Aoki H, Umezawa K, Kranrod J, Miyazaki N, Oshima T, Hirao T, Miura Y, Seubert J, Ito K, Aoki S.
Potential role of lipophagy impairment for anticancer effects of glycolysis-suppressed pancreatic ductal adenocarcinoma cells.
Cell Death Discov
2024
10(1):166
PubMed ID: 38580661
DOI: 10.1038/s41420-024-01933-4
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18285
Yamakawa K, Koyanagi-Aoi M, Machinaga A, Kakiuchi N, Hirano T, Kodama Y, Aoi T.
Blockage of retinoic acid signaling via RARγ suppressed the proliferation of pancreatic cancer cells by arresting the cell cycle progression of the G1-S phase
Cancer Cell Int
2023
23(1):94
PubMed ID: 37198667
DOI: 10.1186/s12935-023-02928-4
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19924
Yoo HB, Moon JW, Kim HR, Lee HS, Miyabayashi K, Park CH, Ge S, Zhang A, Tae YK, Sub Y, Park HW, Gee HY, Notta F, Tuveson DA, Bang S, Kim MY, Roe JS.
A TEAD2-Driven Endothelial-Like Program Shapes Basal-Like Differentiation and Metastasis of Pancreatic Cancer
Gastroenterology
2023
165(1):133-148.e17
PubMed ID: 36907523
DOI: 10.1053/j.gastro.2023.02.049
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21434
Rajbhandari N, Hamilton M, Quintero CM, Ferguson LP, Fox R, Schürch CM, Wang J, Nakamura M, Lytle NK, McDermott M, Diaz E, Pettit H, Kritzik M, Han H, Cridebring D, Wen KW, Tsai S, Goggins MG, Lowy AM, Wechsler-Reya RJ, Von Hoff DD, Newman AM, Reya T.
Single-cell mapping identifies MSI+ cells as a common origin for diverse subtypes of pancreatic cancer.
Cancer Cell
2023
PubMed ID: 37802055
DOI: 10.1016/j.ccell.2023.09.008
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20570
Vaes RDW, van Dijk DPJ, Farshadi EA, Olde Damink SWM, Rensen SS, Langen RC.
Human pancreatic tumour organoid-derived factors enhance myogenic differentiation.
J Cachexia Sarcopenia Muscle
2022
PubMed ID: 35146962
DOI: 10.1002/jcsm.12917
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20717
Yamakawa K, Koyanagi-Aoi M, Uehara K, Masuda A, Yanagimoto H, Toyama H, Fukumoto T, Kodama Y, Aoi T.
Increased expression of SPRR1A is associated with a poor prognosis in pancreatic ductal adenocarcinoma.
PLoS One
2022
17(5)
PubMed ID: 35617311
DOI: 10.1371/journal.pone.0266620
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20747
Kabashima A, Matsuo Y, Ito S, Akiyama Y, Ishii T, Shimada S, Masamune A, Tanabe M, Tanaka S.
cGAS-STING signaling encourages immune cell overcoming of fibroblast barricades in pancreatic cancer.
Sci Rep
2022
12(1):10466
PubMed ID: 35773436
DOI: 10.1038/s41598-022-14297-5
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20976
Liu Z, Hayashi H, Matsumura K, Ogata Y, Sato H, Shiraishi Y, Uemura N, Miyata T, Higashi T, Nakagawa S, Mima K, Imai K, Baba H.
Hyperglycaemia induces metabolic reprogramming into a glycolytic phenotype and promotes epithelial-mesenchymal transitions via YAP/TAZ-Hedgehog signalling axis in pancreatic cancer.
Br J Cancer
2022
PubMed ID: 36536047
DOI: 10.1038/s41416-022-02106-9
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20108
Tasaki Y, Suzuki M, Katsushima K, Shinjo K, Iijima K, Murofushi Y, Naiki-Ito A, Hayashi K, Qiu C, Takahashi A, Tanaka Y, Kawaguchi T, Sugawara M, Kataoka T, Naito M, Miyata K, Kataoka K, Noda T, Gao W, Kataoka H, Takahashi S, Kimura K, Kondo Y.
Cancer-Specific Targeting of Taurine-Upregulated Gene 1 Enhances the Effects of Chemotherapy in Pancreatic Cancer.
Cancer Res
2021
PubMed ID: 33648930
DOI: 10.1158/0008-5472.CAN-20-3021
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20289
Brennan G, Ryan S, Soulimane T, Tofail SAM, Silien C.
Dark Field and Coherent Anti-Stokes Raman (DF-CARS) Imaging of Cell Uptake of Core-Shell, Magnetic-Plasmonic Nanoparticles.
Nanomaterials (Basel)
2021
11(3)
PubMed ID: 33803430
DOI: 10.3390/nano11030685
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20433
Bitorina AV, Oligschlaeger Y, Ding L, Yadati T, Westheim A, Houben T, Vaes RDW, Olde Damink SWM, Theys J, Shiri-Sverdlov R.
OxLDL as an Inducer of a Metabolic Shift in Cancer Cells.
J Cancer
2021
12(19):5817-5824
PubMed ID: 34475995
DOI: 10.7150/jca.56307
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13240
Onodera T, Momose I, Adachi H, Yamazaki Y, Sawa R, Ohba SI, Kawada M.
Human pancreatic cancer cells under nutrient deprivation are vulnerable to redox system inhibition.
J Biol Chem
2020
PubMed ID: 32978257
DOI: 10.1074/jbc.RA120.013893
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14803
Kushibiki T, Nakamura T, Tsuda M, Tsuchikawa T, Hontani K, Inoko K, Takahashi M, Asano T, Okamura K, Murakami S, Kurashima Y, Ebihara Y, Noji T, Nakanishi Y, Tanaka K, Maishi N, Sasaki K, Park WR, Shichinohe T, Hida K, Tanaka S, Hirano S.
Role of Dimerized C16orf74 in Aggressive Pancreatic Cancer: A Novel Therapeutic Target
Mol Cancer Ther
2020
19(1):187-198
PubMed ID: 31597713
DOI: 10.1158/1535-7163.MCT-19-0491
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5030
Tsukamoto M, Imai K, Ishimoto T, Komohara Y, Yamashita YI, Nakagawa S, Umezaki N, Yamao T, Kitano Y, Miyata T, Arima K, Okabe H, Baba Y, Chikamoto A, Ishiko T, Hirota M, Baba H.
PD-L1 expression enhancement by infiltrating macrophage-derived tumor necrosis factor-α leads to poor pancreatic cancer prognosis.
Cancer Sci
2019
110(1):310-320
PubMed ID: 30426611
DOI: 10.1111/cas.13874
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11811
Mohammad GH, Vassileva V, Acedo P, Olde Damink SWM, Malago M, Dhar DK, Pereira SP.
Targeting Pyruvate Kinase M2 and Lactate Dehydrogenase A Is an Effective Combination Strategy for the Treatment of Pancreatic Cancer.
Cancers (Basel)
2019
11(9):1372
PubMed ID: 31527446
DOI: 10.3390/cancers11091372
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11862
Afify SM, Chen L, Yan T, Calle AS, Nair N, Murakami C, Zahra MH, Okada N, Iwasaki Y, Seno A, Seno M.
Method to Convert Stem Cells into Cancer Stem Cells.
Methods Protoc
2019
PubMed ID: 31426391
DOI: 10.3390/mps2030071
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9183
Maria New, Tim Van Acker Jun-Ichi Sakamaki, Ming Jiang, Rebecca E Saunders, Jaclyn Long, Victoria M-Y Wang, Axel Behrens, Joana Cerveira, Padhmanand Sudhakar, Tamas Korcsmaros, Harold B J Jefferies, Kevin M Ryan, Michael Howell, Sharon A Tooze
MDH1 and MPP7 Regulate Autophagy in Pancreatic Ductal Adenocarcinoma
Cancer Res
2019
79 (8), 1884-1898
PubMed ID: 30765601
DOI: 10.1158/0008-5472.CAN-18-2553
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10320
Kasai S, Sasaki T, Watanabe A, Nishiya M, Yasuhira S, Shibazaki M, Maesawa C.
Bcl-2/Bcl-xL inhibitor ABT-737 sensitizes pancreatic ductal adenocarcinoma to paclitaxel-induced cell death.
Oncol Lett
2017
14:903-908
PubMed ID: 28693250
DOI: 10.3892/ol.2017.6211
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10466
Machihara K, Tanaka H, Hayashi Y, Murakami I, Namba T.
Questiomycin A stimulates sorafenib-induced cell death via suppression of glucose-regulated protein 78.
Biochem. Biophys. Res. Commun.
2017
492:33-40
PubMed ID: 28811106
DOI: 10.1016/j.bbrc.2017.08.042
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14655
Ohishi T, Yoshida H, Katori M, Migita T, Muramatsu Y, Miyake M, Ishikawa Y, Saiura A, Iemura SI, Natsume T, Seimiya H.
Tankyrase-Binding Protein TNKS1BP1 Regulates Actin Cytoskeleton Rearrangement and Cancer Cell Invasion
Cancer Res
2017
77(9):2328-2338
PubMed ID: 28202517
DOI: 10.1158/0008-5472.CAN-16-1846
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7044
Calle AS, Nair N, Oo AK, Prieto-Vila M, Koga M, Khayrani AC, Hussein M, Hurley L, Vaidyanath A, Seno A, Iwasaki Y, Calle M, Kasai T, Seno M.
A new PDAC mouse model originated from iPSCs-converted pancreatic cancer stem cells (CSCcm).
Am J Cancer Res
2016
6:2799-2815
PubMed ID: 28042501
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9938
Komura D, Isagawa T, Kishi K, Suzuki R, Sato R, Tanaka M, Katoh H, Yamamoto S, Tatsuno K, Fukayama M, Aburatani H, Ishikawa S.
CASTIN: a system for comprehensive analysis of cancer-stromal interactome.
BMC Genomics
2016
17:899
PubMed ID: 27829362
DOI: 10.1186/s12864-016-3207-z
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12659
Mohammad GH, Olde Damink SW, Malago M, Dhar DK, Pereira SP.
Pyruvate Kinase M2 and Lactate Dehydrogenase A Are Overexpressed in Pancreatic Cancer and Correlate with Poor Outcome
PLoS One
2016
11(3):e0151635
PubMed ID: 26989901
DOI: 10.1371/journal.pone.0151635
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7300
Namba T, Kodama R, Moritomo S, Hoshino T, Mizushima T.
Zidovudine, an anti-viral drug, resensitizes gemcitabine-resistant pancreatic cancer cells to gemcitabine by inhibition of the Akt-GSK3β-Snail pathway.
Cell Death Dis
2015
6:e1795
PubMed ID: 26111057
DOI: 10.1038/cddis.2015.172
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7425
Hollevoet K, Mason-Osann E, Muller F, Pastan I.
Methylation-associated partial down-regulation of mesothelin causes resistance to anti-mesothelin immunotoxins in a pancreatic cancer cell line.
PLoS ONE
2015
10:e0122462
PubMed ID: 25803818
DOI: 10.1371/journal.pone.0122462
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5025
Sakamoto K, Imai K, Higashi T, Taki K, Nakagawa S, Okabe H, Nitta H, Hayashi H, Chikamoto A, Ishiko T, Beppu T, Baba H.
Significance of P-cadherin overexpression and possible mechanism of its regulation in intrahepatic cholangiocarcinoma and pancreatic cancer.
Cancer Sci
2015
106(9):1153-62
PubMed ID: 26132727
DOI: 10.1111/cas.12732
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15159
Honda S, Loher P, Shigematsu M, Palazzo JP, Suzuki R, Imoto I, Rigoutsos I, Kirino Y.
Sex hormone-dependent tRNA halves enhance cell proliferation in breast and prostate cancers
Proc Natl Acad Sci U S A
2015
112(29):E3816-25
PubMed ID: 26124144
DOI: 10.1073/pnas.1510077112
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15259
Namba T, Kodama R.
Avarol induces apoptosis in pancreatic ductal adenocarcinoma cells by activating PERK-eIF2α-CHOP signaling
Mar Drugs
2015
13(4):2376-89
PubMed ID: 25894488
DOI: 10.3390/md13042376
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14319
Hollevoet K, Antignani A, Fitzgerald DJ, Pastan I.
Combining the antimesothelin immunotoxin SS1P with the BH3-mimetic ABT-737 induces cell death in SS1P-resistant pancreatic cancer cells
J Immunother
2014
37(1):8-15
PubMed ID: 24316551
DOI: 10.1097/CJI.0000000000000010
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14322
Mattoo AR, Pastan I, Fitzgerald D.
Combination treatments with the PKC inhibitor, enzastaurin, enhance the cytotoxicity of the anti-mesothelin immunotoxin, SS1P
PLoS One
2013
8(10):e75576
PubMed ID: 24130723
DOI: 10.1371/journal.pone.0075576
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15922
Fujitani N, Furukawa J, Araki K, Fujioka T, Takegawa Y, Piao J, Nishioka T, Tamura T, Nikaido T, Ito M, Nakamura Y, Shinohara Y.
Total cellular glycomics allows characterizing cells and streamlining the discovery process for cellular biomarkers
Proc Natl Acad Sci U S A
2013
110(6):2105-10
PubMed ID: 23345451
DOI: 10.1073/pnas.1214233110
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19021
Awale S, Ueda JY, Athikomkulchai S, Abdelhamed S, Yokoyama S, Saiki I, Miyatake R.
Antiausterity agents from Uvaria dac and their preferential cytotoxic activity against human pancreatic cancer cell lines in a nutrient-deprived condition
J Nat Prod
2012
75(6):1177-83
PubMed ID: 22676269
DOI: 10.1021/np300295h
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7928
Shoji Y, Miyamoto M, Ishikawa K, Yoshioka T, Mishra R, Ichinokawa K, Matsumura Y, Itoh T, Shinohara T, Hirano S, Kondo S.
The CD40-CD154 interaction would correlate with proliferation and immune escape in pancreatic ductal adenocarcinoma.
J Surg Oncol
2011
103:230-8
PubMed ID: 21337550
DOI: 10.1002/jso.21812
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