Cell No. : Cell Name
RCB2110 : YKG1
update : 2024/08/14
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| Comment | Human cell line derived from glioblastoma. TKG0453 (Deposited from Tohoku Univ.). |
| Comment from the depositor | |
| Terms and conditions | In publishing research results obtained by the use of the BIOLOGICAL RESOURCE, a citation of the literature ref. (Acta Neuropathologica, 79, 30-36, 1989) designated by the DEPOSITOR is required. |
| Remarks | |
| Order Form |
Order Form(C-0005.pdf)
MTA(C-0007.pdf)
MTA(C-0007p.pdf)
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Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
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Basic information
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Depositor |
Obinata, Masuo
|
| Originator |
Kanno, Hiroshi
|
| Year of deposit |
2005
|
| Original cell |
TKG0453
|
| Animal |
_human
< Mammals
|
| Genus |
Homo
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| Species |
sapiens
|
| Tissue |
brain
|
| Disease name |
Glioblastoma
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| Classification |
cancer
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| History |
Cell Resource Center for Biomedical Research, Tohoku University（TKG0453）
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|
Lifespan |
infinite
|
| Morphology |
other
|
| Cellosaurus(Expasy) |
CVCL_1796
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deposit info |
lot info |
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Medium |
Medium List |
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Culture type |
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Adherent cells
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| Culture medium |
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DMEM (low glucose) + 10% FBS
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| Antibiotics |
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Free
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Passage method |
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0.25% Trypsin
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Culture information
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Passage ratio |
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1 : 8 split
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| SC frequency |
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Subculture : 2 times/week
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| Temperature |
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37
℃
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| CO2 concentration |
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5
%
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| Freeze medium |
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Medium + 10% DMSO
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| Freezing method |
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Slow freezing
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| Mycoplasma/Acholeplasma |
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(-)
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| Isozyme |
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LD, NP
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| STR(human) |
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OK
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| Images |
deposit info | lot info |
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| Reference information |
Reference |
1
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| User's Publication |
7
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| User's Publication |
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19695
Yasemin Yuksel, Sefa Celik, Esra Aslan, Murat Tosun, Mukremin Uysal, Mehmet Pektas
Potential cytotoxic effects of borax alone and in combination with irinotecan on YKG1 glioblastoma cell-line
Medicine Science | International Medical Journal
2023
12:26
DOI: 10.5455/medscience.2022.11.253
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4375
Fukushima T, Kawaguchi M, Yamamoto K, Yamashita F, Izumi A, Kaieda T, Takezaki Y, Itoh H, Takeshima H, Kataoka H.
Aberrant methylation and silencing of the SPINT2 gene in high-grade gliomas.
Cancer Sci.
2018
109(9):2970-2979
PubMed ID: 29987920
DOI: 10.1111/cas.13732
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14212
GursesCila HE, Acar M, Barut FB, Gunduz M, Grenman R, Gunduz E.
Investigation of the expression of RIF1 gene on head and neck, pancreatic and brain cancer and cancer stem cells
Clin Invest Med
2016
39(6):27500
PubMed ID: 27917791
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4947
Matsuda Y, Ishiwata T, Yoshimura H, Hagio M, Arai T.
Inhibition of nestin suppresses stem cell phenotype of glioblastomas through the alteration of post-translational modification of heat shock protein HSPA8/HSC71
Cancer Lett
2015
357(2):602-1
PubMed ID: 25527454
DOI: 10.1016/j.canlet.2014.12.030
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16012
Ohashi R, Matsuda Y, Ishiwata T, Naito Z.
Downregulation of fibroblast growth factor receptor 2 and its isoforms correlates with a high proliferation rate and poor prognosis in high-grade glioma
Oncol Rep
2014
32(3):1163-9
PubMed ID: 24968791
DOI: 10.3892/or.2014.3283
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13710
Fukushima T, Kawaguchi M, Yorita K, Tanaka H, Takeshima H, Umezawa K, Kataoka H.
Antitumor effect of dehydroxymethylepoxyquinomicin, a small molecule inhibitor of nuclear factor-κB, on glioblastoma
Neuro Oncol
2012
14(1):19-28
PubMed ID: 21968049
DOI: 10.1093/neuonc/nor168
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3698
Fukushima T, Tezuka T, Shimomura T, Nakano S, Kataoka H.
Silencing of insulin-like growth factor-binding protein-2 in human glioblastoma cells reduces both invasiveness and expression of progression-associated gene CD24.
J Biol Chem
2007
282(25):18634-44
PubMed ID: 17475624
DOI: 10.1074/jbc.M609567200
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