| 利用者成果(英) |
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19591
Kawasaki Y, Omori Y, Suzuki S, Yamada T.
CD98hc as a marker of radiotherapy-resistant cancer stem cells in head and neck squamous cell carcinoma
Arch Med Sci
2023
19(6):1859-1868
PubMed ID: 38058706
DOI: 10.5114/aoms.2020.92872
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20559
Komatsu M, Saito K, Miyamoto I, Koike K, Iyoda M, Nakashima D, Kasamatsu A, Shiiba M, Tanzawa H, Uzawa K.
Aberrant GIMAP2 expression affects oral squamous cell carcinoma progression by promoting cell cycle and inhibiting apoptosis.
Oncol Lett
2022
23(2):49
PubMed ID: 34992682
DOI: 10.3892/ol.2021.13167
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20020
Shishido K, Kuroishi T, Sugawara S.
P2 purinergic receptor signaling and interleukin-1 synergistically induce interleukin-6 production in a human oral squamous carcinoma cell line.
J Oral Biosci
2021
PubMed ID: 33497843
DOI: 10.1016/j.job.2021.01.004
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20085
Kase Y, Uzawa K, Wagai S, Yoshimura S, Yamamoto JI, Toeda Y, Okubo M, Eizuka K, Ando T, Nobuchi T, Kawasaki K, Saito T, Iyoda M, Nakashima D, Kasamatsu A, Tanzawa H.
Engineered exosomes delivering specific tumor-suppressive RNAi attenuate oral cancer progression.
Sci Rep
2021
11(1):5897
PubMed ID: 33723306
DOI: 10.1038/s41598-021-85242-1
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16206
Koma A, Asai S, Minemura C, Oshima S, Kinoshita T, Kikkawa N, Koshizuka K, Moriya S, Kasamatsu A, Hanazawa T, Uzawa K, Seki N.
Impact of Oncogenic Targets by Tumor-Suppressive miR-139-5p and miR-139-3p Regulation in Head and Neck Squamous Cell Carcinoma
Int J Mol Sci
2021
22(18):9947
PubMed ID: 34576110
DOI: 10.3390/ijms22189947
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16975
Hotta H, Hamamura K, Shibuya H, Ohmi Y, Furukawa K, Furukawa K.
Lewis y Expressed in Oral Squamous Cell Carcinoma Attenuates Malignant Properties via Down-regulation of EGF Signaling
Anticancer Res
2021
41(4):1821-1830
PubMed ID: 33813387
DOI: 10.21873/anticanres.14948
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13903
Aika Tanzawa et al.
Comprehensive gene expression analysis of semaphorins in oral squamous cell carcinoma
Oral Science International
2020
17(2):67-72
DOI: 10.1002/osi2.1044
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11354
Nakamura Y, Nakahata S, Kondo Y, Izumi A, Yamamoto K, Ichikawa T, Tamura T, Noumi K, Yamashita Y, Morishita K.
Overexpression of absent in melanoma 2 in oral squamous cell carcinoma contributes to tumor progression.
Biochem. Biophys. Res. Commun.
2019
PubMed ID: 30587341
DOI: 10.1016/j.bbrc.2018.12.066
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9696
Kazuya Hiroshima, Masashi Shiiba, Noritoshi Oka, Fumihiko Hayashi, Sho Ishida, Reo Fukushima, Kazuyuki Koike, Manabu Iyoda, Dai Nakashima, Hideki Tanzawa, Katsuhiro Uzawa
Tspan15 Plays a Crucial Role in Metastasis in Oral Squamous Cell Carcinoma
Exp Cell Res
2019
384(2):111622
PubMed ID: 31518558
DOI: 10.1016/j.yexcr.2019.111622
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11907
Cervino G, Fiorillo L, Herford AS, Romeo U, Bianchi A, Crimi S, D'Amico C, De Stefano R, Troiano G, Santoro R, Laino L, Laino G, Cicciù M.
Molecular Biomarkers Related to Oral Carcinoma: Clinical Trial Outcome Evaluation in a Literature Review.
Dis. Markers
2019
PubMed ID: 31019584
DOI: 10.1155/2019/8040361
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12586
Sato K, Shi L, Ito F, Ohara Y, Motooka Y, Tanaka H, Mizuno M, Hori M, Hirayama T, Hibi H, Toyokuni S.
Non-thermal plasma specifically kills oral squamous cell carcinoma cells in a catalytic Fe(II)-dependent manner
J Clin Biochem Nutr
2019
65(1):8-15
PubMed ID: 31379408
DOI: 10.3164/jcbn.18-91
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10682
Yamamoto JI, Kasamatsu A, Okubo Y, Nakashima D, Fushimi K, Minakawa Y, Kasama H, Shiiba M, Tanzawa H, Uzawa K.
Evaluation of tryptophan-aspartic acid repeat-containing protein 34 as a novel tumor-suppressor molecule in human oral cancer.
Biochem. Biophys. Res. Commun.
2018
495:2469-2474
PubMed ID: 29278705
DOI: 10.1016/j.bbrc.2017.12.138
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10683
Suzuki S, Hoshino H, Yoshida K, Nakanishi J, Tsuchiya-Hirata S, Kobuke S, Haruyama N, Nishimura F, Shiba H.
Genome-wide identification of chromatin-enriched RNA reveals that unspliced dentin matrix protein-1 mRNA regulates cell proliferation in squamous cell carcinoma.
Biochem. Biophys. Res. Commun.
2018
495:2303-2309
PubMed ID: 29278708
DOI: 10.1016/j.bbrc.2017.12.136
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10806
Okubo Y, Kasamatsu A, Yamatoji M, Fushimi K, Ishigami T, Shimizu T, Kasama H, Shiiba M, Tanzawa H, Uzawa K.
Diacylglycerol lipase alpha promotes tumorigenesis in oral cancer by cell-cycle progression.
Exp. Cell Res.
2018
367:112-118
PubMed ID: 29614312
DOI: 10.1016/j.yexcr.2018.03.041
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10820
Fukamachi M, Kasamatsu A, Endo-Sakamoto Y, Fushimi K, Kasama H, Iyoda M, Minakawa Y, Shiiba M, Tanzawa H, Uzawa K.
Multiple coagulation factor deficiency protein 2 as a crucial component in metastasis of human oral cancer.
Exp. Cell Res.
2018
368:119-125
PubMed ID: 29679592
DOI: 10.1016/j.yexcr.2018.04.021
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11180
Toeda Y, Kasamatsu A, Koike K, Endo-Sakamoto Y, Fushimi K, Kasama H, Yamano Y, Shiiba M, Tanzawa H, Uzawa K.
FBLIM1 enhances oral cancer malignancy via modulation of the epidermal growth factor receptor pathway.
Mol. Carcinog.
2018
57(12):1690-1697
PubMed ID: 30129678
DOI: 10.1002/mc.22889
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11192
Miyaguchi J, Shiga K, Ogawa K, Suzuki F, Katagiri K, Saito D, Ikeda A, Horii A, Watanabe M, Igimi S.
Treatment with Lactobacillus Retards the Tumor Growth of Head and Neck Squamous Cell Carcinoma Cells Inoculated in Mice.
Tohoku J. Exp. Med.
2018
245(4):269-275
PubMed ID: 30158369
DOI: 10.1620/tjem.245.269
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11226
Fukushima R, Kasamatsu A, Nakashima D, Higo M, Fushimi K, Kasama H, Endo-Sakamoto Y, Shiiba M, Tanzawa H, Uzawa K.
Overexpression of Translocation Associated Membrane Protein 2 Leading to Cancer-Associated Matrix Metalloproteinase Activation as a Putative Metastatic Factor for Human Oral Cancer.
J Cancer
2018
PubMed ID: 30271493
DOI: 10.7150/jca.25666
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4345
Hou B, Ishinaga H, Midorikawa K, Nakamura S, Hiraku Y, Oikawa S, Ma N, Takeuchi K, Murata M.
Let-7c inhibits migration and epithelial-mesenchymal transition in head and neck squamous cell carcinoma by targeting IGF1R and HMGA2.
Oncotarget
2018
PubMed ID: 29507664
DOI: 10.18632/oncotarget.23826
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16201
Sawai Y, Kasamatsu A, Nakashima D, Fushimi K, Kasama H, Iyoda M, Kouzu Y, Shiiba M, Tanzawa H, Uzawa K.
Critical role of deoxynucleotidyl transferase terminal interacting protein 1 in oral cancer
Lab Invest
2018
98(8):980-988
PubMed ID: 29855544
DOI: 10.1038/s41374-018-0070-3
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10148
Takahara T, Kasamatsu A, Yamatoji M, Iyoda M, Kasama H, Saito T, Takeuchi S, Endo-Sakamoto Y, Shiiba M, Tanzawa H, Uzawa K.
SIPA1 promotes invasion and migration in human oral squamous cell carcinoma by ITGB1 and MMP7.
Exp. Cell Res.
2017
352:357-363
PubMed ID: 28237246
DOI: 10.1016/j.yexcr.2017.02.026
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10155
Koide N, Kasamatsu A, Endo-Sakamoto Y, Ishida S, Shimizu T, Kimura Y, Miyamoto I, Yoshimura S, Shiiba M, Tanzawa H, Uzawa K.
Evidence for Critical Role of Lymphocyte Cytosolic Protein 1 in Oral Cancer.
Sci Rep
2017
7:43379
PubMed ID: 28230172
DOI: 10.1038/srep43379
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10191
Takeuchi S, Kasamatsu A, Yamatoji M, Nakashima D, Endo-Sakamoto Y, Koide N, Takahara T, Shimizu T, Iyoda M, Ogawara K, Shiiba M, Tanzawa H, Uzawa K.
TEAD4-YAP interaction regulates tumoral growth by controlling cell-cycle arrest at the G1 phase.
Biochem. Biophys. Res. Commun.
2017
486:385-390
PubMed ID: 28315328
DOI: 10.1016/j.bbrc.2017.03.050
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10418
Kita A, Kasamatsu A, Nakashima D, Endo-Sakamoto Y, Ishida S, Shimizu T, Kimura Y, Miyamoto I, Yoshimura S, Shiiba M, Tanzawa H, Uzawa K.
Activin B Regulates Adhesion, Invasiveness, and Migratory Activities in Oral Cancer: a Potential Biomarker for Metastasis.
J Cancer
2017
8:2033-2041
PubMed ID: 28819404
DOI: 10.7150/jca.18714
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11036
Increased Expression of CD44v9, A Cancer Stem Cell Marker, in Head And Neck Squamous Cell Carcinoma Cells after Irradiation
Int J Cancer Oncol
2017
4: 225- 230
DOI: 10.15436/2377-0902.17.1628
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6027
lNorihisa Ichimura et al
Notch3 is frequently downregulated in oral cancer
Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology
2017
29:504-510
DOI: 10.1016/j.ajoms.2017.06.006
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6029
Ishida S et al
Novel mechanism of aberrant ZIP4 expression with zinc supplementation in oral tumorigenesis.
Biochem Biophys Res Commun
2017
483(1):339-345
PubMed ID: 28017725
DOI: 10.1016/j.bbrc.2016.12.142
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12679
Tamura T, Ichikawa T, Nakahata S, Kondo Y, Tagawa Y, Yamamoto K, Nagai K, Baba T, Yamaguchi R, Futakuchi M, Yamashita Y, Morishita K.
Loss of NDRG2 Expression Confers Oral Squamous Cell Carcinoma with Enhanced Metastatic Potential
Cancer Res
2017
77(9):2363-2374
PubMed ID: 28209617
DOI: 10.1158/0008-5472.CAN-16-2114
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14306
Noriko Komatsu, Kenichi Mitsui, Osamu Kusano-Arai, Hiroko Iwanari, Kazuto Hoshi, Tsuyoshi Takato, Takahiro Abe and Takao Hamakubo
Enhancement of anti-robo1 immunotoxin cytotoxicity to head and neck squamous cell carcinoma via photochemical internalization
Archives in Cancer Research
2017
5
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9616
Kitajima D, Kasamatsu A, Nakashima D, Miyamoto I, Kimura Y, Saito T, Suzuki T, Endo-Sakamoto Y, Shiiba M, Tanzawa H, Uzawa K.
Tie2 Regulates Tumor Metastasis of Oral Squamous Cell Carcinomas.
J Cancer
2016
7:600-7
PubMed ID: 27053959
DOI: 10.7150/jca.13820
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9630
Kimura Y, Kasamatsu A, Nakashima D, Yamatoji M, Minakawa Y, Koike K, Fushimi K, Higo M, Endo-Sakamoto Y, Shiiba M, Tanzawa H, Uzawa K.
ARNT2 Regulates Tumoral Growth in Oral Squamous Cell Carcinoma.
J Cancer
2016
7:702-10
PubMed ID: 27076852
DOI: 10.7150/jca.14208
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6036
Suzuki T, Kasamatsu A, Miyamoto I, Saito T, Higo M, Endo-Sakamoto Y, Shiiba M, Tanzawa H, Uzawa K.
Overexpression of TMOD1 is associated with enhanced regional lymph node metastasis in human oral cancer.
Int J Oncol.
2016
48(2):607-12
PubMed ID: 26718916
DOI: 10.3892/ijo.2015.3305
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7442
Shirako Y, Taya Y, Sato K, Chiba T, Imai K, Shimazu Y, Aoba T, Soeno Y.
Heterogeneous tumor stromal microenvironments of oral squamous cell carcinoma cells in tongue and nodal metastatic lesions in a xenograft mouse model.
J. Oral Pathol. Med.
2015
44:656-68
PubMed ID: 25765182
DOI: 10.1111/jop.12318
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6044
Kasama H et al
Adenosine A2b receptor promotes progression of human oral cancer.
BMC Cancer
2015
15:563
PubMed ID: 26228921
DOI: 10.1186/s12885-015-1577-2
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6051
Okamoto A et al
Down-Regulation of Nucleolar and Spindle-Associated Protein 1 (NUSAP1) Expression Suppresses Tumor and Cell Proliferation and Enhances Anti-Tumor Effect of Paclitaxel in Oral Squamous Cell Carcinoma.
PLoS One
2015
10(11):e0142252
PubMed ID: 26554377
DOI: 10.1371/journal.pone.0142252
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6052
Saito T et al
Semaphorin7A Promotion of Tumoral Growth and Metastasis in Human Oral Cancer by Regulation of G1 Cell Cycle and Matrix Metalloproteases: Possible Contribution to Tumoral Angiogenesis.
PLoS One
2015
10(9):e0137923
PubMed ID: 26378920
DOI: 10.1371/journal.pone.0137923
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6058
Shida-Sakazume T et al
Lysophosphatidylcholine acyltransferase1 overexpression promotes oral squamous cell carcinoma progression via enhanced biosynthesis of platelet-activating factor.
PLoS One.
2015
10(3):e0120143
PubMed ID: 25803864
DOI: 10.1371/journal.pone.0120143
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14987
Kaneko T, Kanno C, Ichikawa-Tomikawa N, Kashiwagi K, Yaginuma N, Ohkoshi C, Tanaka M, Sugino T, Imura T, Hasegawa H, Chiba H.
Liver X receptor reduces proliferation of human oral cancer cells by promoting cholesterol efflux via up-regulation of ABCA1 expression
Oncotarget
2015
6(32):33345-57
PubMed ID: 26452260
DOI: 10.18632/oncotarget.5428
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15042
Koyama T, Ogawara K, Kasamatsu A, Okamoto A, Kasama H, Minakawa Y, Shimada K, Yokoe H, Shiiba M, Tanzawa H, Uzawa K.
ANGPTL3 is a novel biomarker as it activates ERK/MAPK pathway in oral cancer
Cancer Med
2015
4(5):759-69
PubMed ID: 25644496
DOI: 10.1002/cam4.418
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16010
Fukumoto C, Nakashima D, Kasamatsu A, Unozawa M, Shida-Sakazume T, Higo M, Ogawara K, Yokoe H, Shiiba M, Tanzawa H, Uzawa K.
WWP2 is overexpressed in human oral cancer, determining tumor size and poor prognosis in patients: downregulation of WWP2 inhibits the AKT signaling and tumor growth in mice
Oncoscience
2014
1(12):807-20
PubMed ID: 25621296
DOI: 10.18632/oncoscience.101
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5028
Saito Y, Kasamatsu A, Yamamoto A, Shimizu T, Yokoe H, Sakamoto Y, Ogawara K, Shiiba M, Tanzawa H, Uzawa K.
ALY as a potential contributor to metastasis in human oral squamous cell carcinoma.
J Cancer Res Clin Oncol
2013
139(4):585-94
PubMed ID: 23242234
DOI: 10.1007/s00432-012-1361-5
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6067
Koike K, Kasamatsu A, Iyoda M, Saito Y, Kouzu Y, Koike H, Sakamoto Y, Ogawara K, Tanzawa H, Uzawa K.
High prevalence of epigenetic inactivation of the human four and a half LIM domains 1 gene in human oral cancer.
Int J Oncol
2013
42(1):141-50
PubMed ID: 23123766
DOI: 10.3892/ijo.2012.1677
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6070
Yamamoto A, Kasamatsu A, Ishige S, Koike K, Saito K, Kouzu Y, Koike H, Sakamoto Y, Ogawara K, Shiiba M, Tanzawa H, Uzawa K.
Exocyst complex component Sec8: a presumed component in the progression of human oral squamous-cell carcinoma by secretion of matrix metalloproteinases.
J Cancer Res Clin Oncol
2013
139(4):533-42
PubMed ID: 23207790
DOI: 10.1007/s00432-012-1356-2
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6072
Uchida F, Uzawa K, Kasamatsu A, Takatori H, Sakamoto Y, Ogawara K, Shiiba M, Bukawa H, Tanzawa H.
Overexpression of CDCA2 in human squamous cell carcinoma: correlation with prevention of G1 phase arrest and apoptosis.
PLoS One
2013
8(2):e56381
PubMed ID: 23418564
DOI: 10.1371/journal.pone.0056381
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6074
Shimizu F1, Shiiba M2, Ogawara K3, Kimura R1, Minakawa Y1, Baba T1, Yokota S, Nakashima D1, Higo M3, Kasamatsu A3, Sakamoto Y3, Tanzawa H4, Uzawa K4.
Overexpression of LIM and SH3 Protein 1 leading to accelerated G2/M phase transition contributes to enhanced tumourigenesis in oral cancer.
PLoS One
2013
8(12):e83187
PubMed ID: 24386158
DOI: 10.1371/journal.pone.0083187
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6076
Minakawa Y, Kasamatsu A, Koike H, Higo M, Nakashima D, Kouzu Y, Sakamoto Y, Ogawara K, Shiiba M, Tanzawa H, Uzawa K.
Kinesin family member 4A: a potential predictor for progression of human oral cancer.
PLoS One. 2
2013
8(12):e85951
PubMed ID: 24386490
DOI: 10.1371/journal.pone.0085951
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6077
Mikami T, Hada T, Chosa N, Ishisaki A, Mizuki H, Takeda Y. Author information
Expression of Wilms' tumor 1 (WT1) in oral squamous cell carcinoma.
J Oral Pathol Med
2013
42(2):133-9
PubMed ID: 22672247
DOI: 10.1111/j.1600-0714.2012.01182.x
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6081
Kimura R, Kasamatsu A, Koyama T, Fukumoto C, Kouzu Y, Higo M, Endo-Sakamoto Y, Ogawara K, Shiiba M, Tanzawa H, Uzawa K.
Glutamate acid decarboxylase 1 promotes metastasis of human oral cancer by β-catenin translocation and MMP7 activation.
BMC Cancer
2013
13:555
PubMed ID: 24261884
DOI: 10.1186/1471-2407-13-555
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6083
Kumai T, Matsuda Y, Oikawa K, Aoki N, Kimura S, Harabuchi Y, Celis E, Kobayashi H.
EGFR inhibitors augment antitumour helper T-cell responses of HER family-specific immunotherapy.
Br J Cancer
2013
109(8):2155-66
PubMed ID: 24045666
DOI: 10.1038/bjc.2013.577
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6110
YOSHIAKI TABUCHI, YUKIHIRO FURUSAWA, SHIGEHITO WADA, KENZO OHTSUKA, TAKASHI KONDO
Silencing Heat Shock Transcription Factor 1 Using Small Interfering RNA Enhances Mild Hyperthermia and Hyperthermia Sensitivity in Human Oral Squamous Cell Carcinoma Cells
Thermal Medicine
2011
27:99-108
DOI: 10.3191/thermalmed.27.99
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8284
Suzuki K, Sakiyama Y, Usui M, Obama T, Kato R, Itabe H, Yamamoto M.
Oxidized low-density lipoprotein increases interleukin-8 production in human gingival epithelial cell line Ca9-22.
J. Periodont. Res.
2010
45:488-95
PubMed ID: 20412422
DOI: 10.1111/j.1600-0765.2009.01263.x
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6120
Furuta H, Kondo Y, Nakahata S, Hamasaki M, Sakoda S, Morishita K.
NDRG2 is a candidate tumor-suppressor for oral squamous-cell carcinoma.
Biochem Biophys Res Commun
2010
391(4):1785-91
PubMed ID: 20045673
DOI: 10.1016/j.bbrc.2009.12.156
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6122
Nomi N, Kodama S, Suzuki M.
Toll-like receptor 3 signaling induces apoptosis in human head and neck cancer via survivin associated pathway.
Oncol Rep
2010
24(1):225-31
PubMed ID: 20514466
DOI: 10.3892/or_00000850
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6410
Danjoh I, Sone H, Noda N, Iimura E, Nagayoshi M, Saijo K, Hiroyama T, Nakamura Y.
Is parainfluenza virus a threatening virus for human cancer cell lines?
Hum Cell
2009
22(3):81-4
PubMed ID: 19624309
DOI: 10.1111/j.1749-0774.2009.00071.x
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