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Cell No. : Cell Name
RCB2100 : TE-11  update : 2024/03/29
CommentHuman cell line derived from esophageal cancer. Moderately differentiated squamous cell carcinoma. TKG0262 (Deposited from Tohoku Univ.).
Comment from the depositor
Terms and conditions1) In publishing the research results to be obtained by use of this cell line, an acknowledgment to the Depositor, Dr. Tetsuro Nishihira is required. 2) There is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC.
Order Form Order Form(C-0005.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)  
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (
Basic information Depositor Obinata, Masuo
Originator Nishihira, Tetsuro
Year of deposit 2005
Original cell TKG0262
Animal _human < Mammals
Genus Homo
Species sapiens
Age at sampling 58 years
Tissue esophagus
Disease name Moderately differntiated squamous carcinoma
Classification cancer
History Cell Resource Center for Biomedical Research, Tohoku University(TKG0262)
Lifespan infinite
Morphology epithelial-like
Cellosaurus(Expasy) CVCL_1761
deposit info
lot info
Medium Medium List
Culture type Adherent cells
Culture medium RPMI1640 + 10% FBS
Antibiotics Free
Passage method 0.25% Trypsin
Culture information Passage ratio 1 : 8 split
SC frequency Subculture : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
Isozyme LD, NP
STR(human) OK
deposit info
lot info
Reference information Reference 0
User's Publication 69

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User's Publication
19698  Takashima Y, Komatsu S, Ohashi T, Kiuchi J, Nishibeppu K, Kamiya H, Arakawa H, Ishida R, Shimizu H, Arita T, Konishi H, Shiozaki A, Kubota T, Fujiwara H, Otsuji E.  Plasma miR-1254 as a predictive biomarker of chemosensitivity and a target of nucleic acid therapy in esophageal cancer  Cancer Sci  2023  114(7):3027-3040  PubMed ID: 37190912   DOI: 10.1111/cas.15830
19768  Tsukamoto S, Koma YI, Kitamura Y, Tanigawa K, Azumi Y, Miyako S, Urakami S, Hosono M, Kodama T, Nishio M, Shigeoka M, Yokozaki H.  Matrix Metalloproteinase 9 Induced in Esophageal Squamous Cell Carcinoma Cells via Close Contact with Tumor-Associated Macrophages Contributes to Cancer Progression and Poor Prognosis  Cancers (Basel)  2023  15(11):2987  PubMed ID: 37296952   DOI: 10.3390/cancers15112987
19965  Azumi Y, Koma YI, Tsukamoto S, Kitamura Y, Ishihara N, Yamanaka K, Nakanishi T, Miyako S, Urakami S, Tanigawa K, Kodama T, Nishio M, Shigeoka M, Kakeji Y, Yokozaki H.  IFI16 Induced by Direct Interaction between Esophageal Squamous Cell Carcinomas and Macrophages Promotes Tumor Progression via Secretion of IL-1α  Cells  2023  12(22):2603  PubMed ID: 37998338   DOI: 10.3390/cells12222603
21054  Kitamura Y, Koma YI, Tanigawa K, Tsukamoto S, Azumi Y, Miyako S, Urakami S, Kodama T, Nishio M, Shigeoka M, Kakeji Y, Yokozaki H.  Roles of IL-7R Induced by Interactions between Cancer Cells and Macrophages in the Progression of Esophageal Squamous Cell Carcinoma.  Cancers (Basel)  2023  15(2)  PubMed ID: 36672342   DOI: 10.3390/cancers15020394
21175  Zhang X, Wang Y, Zhang X, Shen Y, Yang K, Ma Q, Qiao Y, Shi J, Wang Y, Xu L, Yang B, Ge G, Hu L, Kong X, Yang C, Chen Y, Ding J, Meng L.  Intact regulation of G1/S transition renders esophageal squamous cell carcinoma sensitive to PI3Kα inhibitors.  Signal Transduct Target Ther  2023  8(1):153  PubMed ID: 37041169   DOI: 10.1038/s41392-023-01359-x
21406  Nguyen Vu TH, Kikuchi O, Ohashi S, Saito T, Ida T, Nakai Y, Cao Y, Yamamoto Y, Kondo Y, Mitani Y, Kataoka S, Kondo T, Katada C, Yamada A, Matsubara J, Muto M.  Combination therapy with WEE1 inhibition and trifluridine/tipiracil against esophageal squamous cell carcinoma.  Cancer Sci  2023    PubMed ID: 37724648   DOI: 10.1111/cas.15966
21444  Yamada M, Tanaka K, Yamamoto K, Matsumoto H, Yamasaki M, Yamashita K, Makino T, Saito T, Yamamoto K, Takahashi T, Kurokawa Y, Nakajima K, Okada Y, Eguchi H, Doki Y.  Association between circ_0004365 and cisplatin resistance in esophageal squamous cell carcinoma.  Oncol Lett  2023  26(5):467  PubMed ID: 37780544   DOI: 10.3892/ol.2023.14054
17546  Liu J, Liu ZX, Li JJ, Zeng ZL, Wang JH, Luo XJ, Wong CW, Zheng JB, Pu HY, Mo HY, Sheng H, Wu QN, Li H, Wan G, Li B, Wang DS, Xu RH, Ju HQ.  The macrophage-associated lncRNA MALR facilitates ILF3 liquid-liquid phase separation to promote HIF1α signaling in esophageal cancer  Cancer Res  2022  CAN-22-1922  PubMed ID: 36264156   DOI: 10.1158/0008-5472.CAN-22-1922
17703  Tanigawa K, Tsukamoto S, Koma YI, Kitamura Y, Urakami S, Shimizu M, Fujikawa M, Kodama T, Nishio M, Shigeoka M, Kakeji Y, Yokozaki H.  S100A8/A9 Induced by Interaction with Macrophages in Esophageal Squamous Cell Carcinoma Promotes the Migration and Invasion of Cancer Cells via Akt and p38 MAPK Pathways  Am J Pathol  2022  192(3):536-552  PubMed ID: 34954212   DOI: 10.1016/j.ajpath.2021.12.002
20614  Tsuchihashi K, Hirata Y, Yamasaki J, Suina K, Tanoue K, Yae T, Masuda K, Baba E, Akashi K, Kitagawa Y, Saya H, Nagano O.  Presence of spontaneous epithelial-mesenchymal plasticity in esophageal cancer.  Biochem Biophys Rep  2022  30:101246  PubMed ID: 35330672   DOI: 10.1016/j.bbrep.2022.101246
20761  Meng Q, Lu YX, Wei C, Wang ZX, Lin JF, Liao K, Luo XJ, Yu K, Han Y, Li JJ, Tan YT, Li H, Zeng ZL, Li B, Xu RH, Ju HQ.  Arginine methylation of MTHFD1 by PRMT5 enhances anoikis resistance and cancer metastasis.  Oncogene  2022    PubMed ID: 35798877   DOI: 10.1038/s41388-022-02387-7
20071  Matsumoto Y, Shiozaki A, Kosuga T, Kudou M, Shimizu H, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, Otsuji E.  Expression and Role of CFTR in Human Esophageal Squamous Cell Carcinoma.  Ann Surg Oncol  2021    PubMed ID: 33710504   DOI: 10.1245/s10434-021-09752-y
16863  Takaki W, Konishi H, Shoda K, Arita T, Kataoka S, Shibamoto J, Furuke H, Takabatake K, Shimizu H, Komatsu S, Shiozaki A, Fujiwara H, Masuda K, Otsuji E.  Significance of Circular FAT1 as a Prognostic Factor and Tumor Suppressor for Esophageal Squamous Cell Carcinoma  Ann Surg Oncol  2021  28(13):8508-8518  PubMed ID: 34185205   DOI: 10.1245/s10434-021-10089-9
11598  Chen YH, Lu HI, Lo CM, Huang CC, Hsiao CC, Li SH.  The clinical impact of angiotensin-(1-7)/mitochondrial assembly receptor axis in esophageal squamous cell carcinoma patients receiving curative esophagectomy.  J. Formos. Med. Assoc.  2020  119(1 Pt 2):310-318  PubMed ID: 31202501   DOI: 10.1016/j.jfma.2019.05.022
11974  Chen YH, Lu HI, Lo CM, Hsiao CC, Li SH.  NOX4 overexpression is a poor prognostic factor in patients undergoing curative esophagectomy for esophageal squamous cell carcinoma.  Surgery  2020    PubMed ID: 31889545   DOI: 10.1016/j.surg.2019.11.017
12107  Matsubara D, Konishi H, Arita T, Shoda K, Fujita Y, Ogino S, Takao K, Nanishi K, Kosuga T, Komatsu S, Shiozaki A, Fujiwara H, Okamoto K, Otsuji E.  Involvement of Intracellular and Extracellular High-Mobility Group Box-1 in the Progression of Esophageal Squamous Cell Carcinoma.  Ann. Surg. Oncol.  2020    PubMed ID: 32221734   DOI: 10.1245/s10434-020-08363-3
13081  Watanabe N, Kidokoro M, Tanaka M, Inoue S, Tsuji T, Akatuska H, Okada C, Iida Y, Okada Y, Suzuki Y, Sato T, Yahata T, Hirayama N, Nakagawa Y, Inokuchi S.  Podoplanin is indispensable for cell motility and platelet-induced epithelial-to-mesenchymal transition-related gene expression in esophagus squamous carcinoma TE11A cells.  Cancer Cell Int  2020    PubMed ID: 32581653   DOI: 10.1186/s12935-020-01328-2
13092  Feng Y, Yan S, Huang Y, Huang Q, Wang F, Lei Y.  High expression of RABL6 promotes cell proliferation and predicts poor prognosis in esophageal squamous cell carcinoma.  BMC Cancer  2020    PubMed ID: 32600359   DOI: 10.1186/s12885-020-07068-w
13609  Okamoto M, Koma YI, Kodama T, Nishio M, Shigeoka M, Yokozaki H.  Growth Differentiation Factor 15 Promotes Progression of Esophageal Squamous Cell Carcinoma via TGF-β Type II Receptor Activation  Pathobiology  2020  87(2):100-113  PubMed ID: 31896114   DOI: 10.1159/000504394
14800  Ohashi S, Kikuchi O, Nakai Y, Ida T, Saito T, Kondo Y, Yamamoto Y, Mitani Y, Nguyen Vu TH, Fukuyama K, Tsukihara H, Suzuki N, Muto M.  Synthetic Lethality with Trifluridine/Tipiracil and Checkpoint Kinase 1 Inhibitor for Esophageal Squamous Cell Carcinoma  Mol Cancer Ther  2020  19(6):1363-1372  PubMed ID: 32371587   DOI: 10.1158/1535-7163.MCT-19-0918
11491  Shafaee A, Pirayesh Islamian J, Zarei D, Mohammadi M, Nejati-Koshki K, Farajollahi A, Aghamiri SMR, Rahmati Yamchi M, Baradaran B, Asghari Jafarabadi M.  Induction of Apoptosis by a Combination of 2-Deoxyglucose and Metformin in Esophageal Squamous Cell Carcinoma by Targeting Cancer Cell Metabolism.  Iran J Med Sci  2019    PubMed ID: 30936596  
11583  Shi JJ, Xing H, Wang YX, Zhang X, Zhan QM, Geng MY, Ding J, Meng LH.  PI3Kα inhibitors sensitize esophageal squamous cell carcinoma to radiation by abrogating survival signals in tumor cells and tumor microenvironment.  Cancer Lett.  2019    PubMed ID: 31173854   DOI: 10.1016/j.canlet.2019.05.040
11791  Shin WS, Lee HW, Lee ST.  Catalytically inactive receptor tyrosine kinase PTK7 activates FGFR1 independent of FGF.  FASEB J.  2019    PubMed ID: 31490704   DOI: 10.1096/fj.201900932R
11897  Su D, Zhang D, Jin J, Ying L, Han M, Chen K, Li B, Wu J, Xie Z, Zhang F, Lin Y, Cheng G, Li JY, Huang M, Wang J, Wang K, Zhang J, Li F, Xiong L, Futreal A, Mao W.  Identification of predictors of drug sensitivity using patient-derived models of esophageal squamous cell carcinoma.  Nat Commun  2019    PubMed ID: 31700061   DOI: 10.1038/s41467-019-12846-7
11699  Kiyozumi Y, Baba Y, Okadome K, Yagi T, Ogata Y, Eto K, Hiyoshi Y, Ishimoto T, Iwatsuki M, Iwagami S, Miyamoto Y, Yoshida N, Watanabe M, Baba H.  Indoleamine 2, 3-dioxygenase 1 promoter hypomethylation is associated with poor prognosis in patients with esophageal cancer.  Cancer Sci  2019  110(6):1863-1871  PubMed ID: 31012515   DOI: 10.1111/cas.14028
12594  Kalikawe R, Baba Y, Nomoto D, Okadome K, Miyake K, Eto K, Hiyoshi Y, Nagai Y, Iwatsuki M, Ishimoto T, Iwagami S, Miyamoto Y, Yoshida N, Watanabe M, Baba H.  Lysyl oxidase impacts disease outcomes and correlates with global DNA hypomethylation in esophageal cancer  Cancer Sci  2019  110(12):3727-3737  PubMed ID: 31599475   DOI: 10.1111/cas.14214
12595  Sawayama H, Ogata Y, Ishimoto T, Mima K, Hiyoshi Y, Iwatsuki M, Baba Y, Miyamoto Y, Yoshida N, Baba H.  Glucose transporter 1 regulates the proliferation and cisplatin sensitivity of esophageal cancer  Cancer Sci   2019  110(5):1705-1714  PubMed ID: 30861255   DOI: 10.1111/cas.13995
10718  Lee HM, Lee E, Yeo SY, Shin S, Park HK, Nam DH, Kim SH.  Drug repurposing screening identifies bortezomib and panobinostat as drugs targeting cancer associated fibroblasts (CAFs) by synergistic induction of apoptosis.  Invest New Drugs  2018  36(4):545-560  PubMed ID: 29349597   DOI: 10.1007/s10637-017-0547-8
10755  Masuike Y, Tanaka K, Makino T, Yamasaki M, Miyazaki Y, Takahashi T, Kurokawa Y, Nakajima K, Mori M, Doki Y.  Esophageal squamous cell carcinoma with low mitochondrial copy number has mesenchymal and stem-like characteristics, and contributes to poor prognosis.  PLoS ONE  2018  13:e0193159  PubMed ID: 29447301   DOI: 10.1371/journal.pone.0193159
10798  Shinno N, Kimura H, Sada R, Takiguchi S, Mori M, Fumoto K, Doki Y, Kikuchi A.  Activation of the Dickkopf1-CKAP4 pathway is associated with poor prognosis of esophageal cancer and anti-CKAP4 antibody may be a new therapeutic drug.  Oncogene  2018  37(26):3471-3484  PubMed ID: 29563607   DOI: 10.1038/s41388-018-0179-2
4355  Furukawa H, Makino T, Yamasaki M, Tanaka K, Miyazaki Y, Takahashi T, Kurokawa Y, Nakajima K, Takiguchi S, Mori M, Doki Y.  PRIMA-1 induces p53-mediated apoptosis by upregulating Noxa in esophageal squamous cell carcinoma with TP53 missense mutation.  Cancer Sci.  2018  109(2):412-421  PubMed ID: 29168598   DOI: 10.1111/cas.13454
4357  Kim MJ, Choi SK, Hong SH, Eun JW, Nam SW, Han JW, You JS.  Oncogenic IL7R is downregulated by histone deacetylase inhibitor in esophageal squamous cell carcinoma via modulation of acetylated FOXO1.  Int. J. Oncol.  2018  53(1):395-403  PubMed ID: 29749437   DOI: 10.3892/ijo.2018.4392
4504  Piao L, Yang Z, Jin J, Ni W, Qi W, Xuan Y.  B7H4 is associated with stemness and cancer progression in esophageal squamous cell carcinoma.  Hum. Pathol.  2018  80:152-162  PubMed ID: 29885401   DOI: 10.1016/j.humpath.2018.05.021
4505  Yang Z, Ni W, Cui C, Qi W, Piao L, Xuan Y.  Identification of LETM1 as a marker of cancer stem-like cells and predictor of poor prognosis in esophageal squamous cell carcinoma.  Hum. Pathol.  2018  81:148-156  PubMed ID: 30031102   DOI: 10.1016/j.humpath.2018.07.001
9448  Chihiro Kajiwara, Katsumi Fumoto, Hirokazu Kimura, Satoshi Nojima, Keita Asano, Kazuki Odagiri, Makoto Yamasaki, Hayato Hikita, Tetsuo Takehara, Yuichiro Doki, Eiichi Morii, Akira Kikuchii  p63-Dependent Dickkopf3 Expression Promotes Esophageal Cancer Cell Proliferation via CKAP4  Cancer Res  2018  78(21):6107-6120  PubMed ID: 30181180   DOI: 10.1158/0008-5472.CAN-18-1749
10141  Sugase T, Takahashi T, Serada S, Nakatsuka R, Fujimoto M, Ohkawara T, Hara H, Nishigaki T, Tanaka K, Miyazaki Y, Makino T, Kurokawa Y, Yamasaki M, Nakajima K, Takiguchi S, Kishimoto T, Mori M, Doki Y, Naka T.  Suppressor of cytokine signaling-1 gene therapy induces potent antitumor effect in patient-derived esophageal squamous cell carcinoma xenograft mice.  Int. J. Cancer  2017  140:2608-2621  PubMed ID: 28233302   DOI: 10.1002/ijc.30666
10353  Kawaguchi T, Komatsu S, Ichikawa D, Hirajima S, Nishimura Y, Konishi H, Shiozaki A, Fujiwara H, Okamoto K, Tsuda H, Otsuji E.  Overexpression of TRIM44 is related to invasive potential and malignant outcomes in esophageal squamous cell carcinoma.  Tumour Biol.  2017  39:1010428317700409  PubMed ID: 28618928   DOI: 10.1177/1010428317700409
10365  Yamamoto M, Yamasaki M, Tsukao Y, Tanaka K, Miyazaki Y, Makino T, Takahashi T, Kurokawa Y, Nakajima K, Takiguchi S, Mori M, Doki Y.  Poly (ADP-ribose) polymerase-1 inhibition decreases proliferation through G2/M arrest in esophageal squamous cell carcinoma.  Oncol Lett  2017  14:1581-1587  PubMed ID: 28789382   DOI: 10.3892/ol.2017.6334
10449  Yoshioka M, Ohashi S, Ida T, Nakai Y, Kikuchi O, Amanuma Y, Matsubara J, Yamada A, Miyamoto S, Natsuizaka M, Nakagawa H, Chiba T, Seno H, Muto M.  Distinct effects of EGFR inhibitors on epithelial- and mesenchymal-like esophageal squamous cell carcinoma cells.  J. Exp. Clin. Cancer Res.  2017  36:101  PubMed ID: 28764725   DOI: 10.1186/s13046-017-0572-7
10555  Yamashita K, Miyata H, Makino T, Masuike Y, Furukawa H, Tanaka K, Miyazaki Y, Takahashi T, Kurokawa Y, Yamasaki M, Nakajima K, Takiguchi S, Morii E, Mori M, Doki Y.  High Expression of the Mitophagy-Related Protein Pink1 is Associated with a Poor Response to Chemotherapy and a Poor Prognosis for Patients Treated with Neoadjuvant Chemotherapy for Esophageal Squamous Cell Carcinoma.  Ann. Surg. Oncol.  2017  24:4025-4032  PubMed ID: 29022200   DOI: 10.1245/s10434-017-6096-8
10977    Role of HDM2 Gene in Radio-Sensitivity of Esophageal Cancer Cell Lines to Irradiation  Int J Cancer Manag  2017  10:e8950    DOI: 10.5812/ijcm.8950
14630  Harada E, Serada S, Fujimoto M, Takahashi Y, Takahashi T, Hara H, Nakatsuka R, Sugase T, Nishigaki T, Saito Y, Hiramatsu K, Nojima S, Mitsuo R, Ohkawara T, Morii E, Mori M, Doki Y, Kaneda Y, Naka T.  Glypican-1 targeted antibody-based therapy induces preclinical antitumor activity against esophageal squamous cell carcinoma  Oncotarget  2017  8(15):24741-24752  PubMed ID: 28445969   DOI: 10.18632/oncotarget.15799
14752  Yeo SY, Ha SY, Lee KW, Cui Y, Yang ZT, Xuan YH, Kim SH.  Twist1 is highly expressed in cancer-associated fibroblasts of esophageal squamous cell carcinoma with a prognostic significance  Oncotarget  2017  8(39):65265-65280  PubMed ID: 29029429   DOI: 10.18632/oncotarget.17941
9599  Kikuchi O, Ohashi S, Horibe T, Kohno M, Nakai Y, Miyamoto S, Chiba T, Muto M, Kawakami K.  Novel EGFR-targeted strategy with hybrid peptide against oesophageal squamous cell carcinoma.  Sci Rep  2016  6:22452  PubMed ID: 26956916   DOI: 10.1038/srep22452
9656  Nakahara Y, Yamasaki M, Sawada G, Miyazaki Y, Makino T, Takahashi T, Kurokawa Y, Nakajima K, Takiguchi S, Mimori K, Mori M, Doki Y.  Downregulation of SIRT4 Expression Is Associated with Poor Prognosis in Esophageal Squamous Cell Carcinoma.  Oncology  2016  90:347-55  PubMed ID: 27082627   DOI: 10.1159/000445323
9724  Hara H, Takahashi T, Serada S, Fujimoto M, Ohkawara T, Nakatsuka R, Harada E, Nishigaki T, Takahashi Y, Nojima S, Miyazaki Y, Makino T, Kurokawa Y, Yamasaki M, Miyata H, Nakajima K, Takiguchi S, Morii E, Mori M, Doki Y, Naka T.  Overexpression of glypican-1 implicates poor prognosis and their chemoresistance in oesophageal squamous cell carcinoma.  Br. J. Cancer  2016  115:66-75  PubMed ID: 27310703   DOI: 10.1038/bjc.2016.183
9433  Yunyan Wu, Qiang Liu, Xu Yan, Yukio Kato, Makiko Tanaka, Sadaki Inokuchi, Tadashi Yoshizawa, Satoko Morohashi, Hiroshi Kijima  Podoplanin-mediated TGF-β-induced Epithelial-Mesenchymal Transition and Its Correlation With bHLH Transcription Factor DEC in TE-11 Cells  Int J Oncol  2016  48(6):2310-20  PubMed ID: 27035755   DOI: 10.3892/ijo.2016.3445
12664  Shin WS, Hong Y, Lee HW, Lee ST.  Catalytically defective receptor protein tyrosine kinase PTK7 enhances invasive phenotype by inducing MMP-9 through activation of AP-1 and NF-κB in esophageal squamous cell carcinoma cells  Oncotarget  2016  7(45):73242-73256  PubMed ID: 27689325   DOI: 10.18632/oncotarget.12303
12903  Nishio M, Urakawa N, Shigeoka M, Takase N, Ichihara Y, Arai N, Koma Y, Yokozaki H.  Software-assisted morphometric and phenotype analyses of human peripheral blood monocyte-derived macrophages induced by a microenvironment model of human esophageal squamous cell carcinoma  Pathol Int  2016  66(2):83-93  PubMed ID: 26778807   DOI: 10.1111/pin.12381
12969  Hamada J, Shoda K, Masuda K, Fujita Y, Naruto T, Kohmoto T, Miyakami Y, Watanabe M, Kudo Y, Fujiwara H, Ichikawa D, Otsuji E, Imoto I.  Tumor-promoting function and prognostic significance of the RNA-binding protein T-cell intracellular antigen-1 in esophageal squamous cell carcinoma  Oncotarget  2016  7(13):17111-28  PubMed ID: 26958940   DOI: 10.18632/oncotarget.7937
13992  Nakamura K, Baba Y, Kosumi K, Harada K, Shigaki H, Miyake K, Kiyozumi Y, Ohuchi M, Kurashige J, Ishimoto T, Iwatsuki M, Sakamoto Y, Yoshida N, Watanabe M, Nakao M, Baba H.  UHRF1 regulates global DNA hypomethylation and is associated with poor prognosis in esophageal squamous cell carcinoma  Oncotarget  2016  7(36):57821-5783  PubMed ID: 27507047   DOI: 10.18632/oncotarget.11067
13993  Pirayesh Islamian J, Mohammadi M, Baradaran B, Farajollahi A, Aghamiri SM, Asghari Jafarabadi M, Karami H, Monfaredan A, Shanehbandi D.  Enhancing radiosensitivity of TE1, TE8, and TE 11 esophageal squamous carcinoma cell lines by Hdm2-siRNA targeted gene therapy in vitro  Bioimpacts  2016  6(2):93-8  PubMed ID: 27525226   DOI: 10.15171/bi.2016.13
14119  Park M, Yoon HJ, Kang MC, Kwon J, Lee HW.  PTK7 regulates radioresistance through nuclear factor-kappa B in esophageal squamous cell carcinoma  Tumour Biol  2016  37(10):14217-14224  PubMed ID: 27557627   DOI: 10.1007/s13277-016-5288-3
7350  Nabeki B, Ishigami S, Uchikado Y, Sasaki K, Kita Y, Okumura H, Arigami T, Kijima Y, Kurahara H, Maemura K, Natsugoe S.  Interleukin-32 expression and Treg infiltration in esophageal squamous cell carcinoma.  Anticancer Res.  2015  35:2941-7  PubMed ID: 25964580  
7382  Saito S, Morishima K, Ui T, Hoshino H, Matsubara D, Ishikawa S, Aburatani H, Fukayama M, Hosoya Y, Sata N, Lefor AK, Yasuda Y, Niki T.  The role of HGF/MET and FGF/FGFR in fibroblast-derived growth stimulation and lapatinib-resistance of esophageal squamous cell carcinoma.  BMC Cancer  2015  15:82  PubMed ID: 25884729   DOI: 10.1186/s12885-015-1065-8
14284  Bill A, Gutierrez A, Kulkarni S, Kemp C, Bonenfant D, Voshol H, Duvvuri U, Gaither LA.  ANO1/TMEM16A interacts with EGFR and correlates with sensitivity to EGFR-targeting therapy in head and neck cancer  Oncotarget  2015  6(11):9173-88  PubMed ID: 25823819   DOI: 10.18632/oncotarget.3277
15159  Honda S, Loher P, Shigematsu M, Palazzo JP, Suzuki R, Imoto I, Rigoutsos I, Kirino Y.  Sex hormone-dependent tRNA halves enhance cell proliferation in breast and prostate cancers  Proc Natl Acad Sci U S A  2015  112(29):E3816-25  PubMed ID: 26124144   DOI: 10.1073/pnas.1510077112
15184  Harada K, Baba Y, Ishimoto T, Kosumi K, Tokunaga R, Izumi D, Ohuchi M, Nakamura K, Kiyozumi Y, Kurashige J, Iwagami S, Miyamoto Y, Sakamoto Y, Yoshida N, Oki E, Watanabe M, Baba H.  Suppressor microRNA-145 Is Epigenetically Regulated by Promoter Hypermethylation in Esophageal Squamous Cell Carcinom  Anticancer Res  2015  35(9):4617-24  PubMed ID: 26254350  
15229  Shigeoka M, Urakawa N, Nishio M, Takase N, Utsunomiya S, Akiyama H, Kakeji Y, Komori T, Koma Y, Yokozaki H.  Cyr61 promotes CD204 expression and the migration of macrophages via MEK/ERK pathway in esophageal squamous cell carcinoma  Cancer Med  2015  4(3):437-46  PubMed ID: 25620088   DOI: 10.1002/cam4.401
4386  Saito S, Morishima K, Ui T, Matsubara D, Tamura T, Oguni S, Hosoya Y, Sata N, Lefor AT, Yasuda Y, Niki T  Stromal fibroblasts are predictors of disease-related mortality in esophageal squamous cell carcinoma.  Oncol Rep  2014  32(1):348-54  PubMed ID: 24859885   DOI: 10.3892/or.2014.3216
13765  Sawayama H, Ishimoto T, Watanabe M, Yoshida N, Sugihara H, Kurashige J, Hirashima K, Iwatsuki M, Baba Y, Oki E, Morita M, Shiose Y, Baba H.  Small molecule agonists of PPAR-γ exert therapeutic effects in esophageal cancer  Cancer Res  2014  74(2):575-85  PubMed ID: 24272485   DOI: 10.1158/0008-5472.CAN-13-1836
15822  Ohashi S, Kikuchi O, Tsurumaki M, Nakai Y, Kasai H, Horimatsu T, Miyamoto S, Shimizu A, Chiba T, Muto M.  Preclinical validation of talaporfin sodium-mediated photodynamic therapy for esophageal squamous cell carcinoma  PLoS One  2014  9(8):e103126  PubMed ID: 25090101   DOI: 10.1371/journal.pone.0103126
17149  Yeo SY, Ha SY, Yu EJ, Lee KW, Kim JH, Kim SH.  ZNF282 (Zinc finger protein 282), a novel E2F1 co-activator, pr  Oncotarget  2014  5(23):12260-72  PubMed ID: 25373738   DOI: 10.18632/oncotarget.2630
16294  Britschgi A, Bill A, Brinkhaus H, Rothwell C, Clay I, Duss S, Rebhan M, Raman P, Guy CT, Wetzel K, George E, Popa MO, Lilley S, Choudhury H, Gosling M, Wang L, Fitzgerald S, Borawski J, Baffoe J, Labow M, Gaither LA, Bentires-Alj M.  Calcium-activated chloride channel ANO1 promotes breast cancer progression by activating EGFR and CAMK signaling  Proc Natl Acad Sci U S A  2013  110(11):E1026-34  PubMed ID: 23431153   DOI: 10.1073/pnas.1217072110
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