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21184
Chan NN, Yamazaki M, Maruyama S, Abé T, Haga K, Kawaharada M, Izumi K, Kobayashi T, Tanuma JI.
Cholesterol Is a Regulator of CAV1 Localization and Cell Migration in Oral Squamous Cell Carcinoma.
Int J Mol Sci
2023
24(7)
PubMed ID: 37047005
DOI: 10.3390/ijms24076035
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17668
Tsukasa SAKAMOTO , Yuichi OHNISHI, Masami NOZAKI, Masahiro NAKAJIMA, Tomoharu OKAMURA, Kazuya TOMINAGA
Relation to HGF/c‐Met pathway and PD‐L1 expression in oral squamous cell carcinoma
Journal of Osaka Dental University
2022
56:51-61
DOI: 10.18905/jodu.56.1_51
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20382
Fan M, Arai M, Tawada A, Chiba T, Fukushima R, Uzawa K, Shiiba M, Kato N, Tanzawa H, Takiguchi Y.
Contrasting functions of the epithelial‑stromal interaction 1 gene, in human oral and lung squamous cell cancers.
Oncol Rep
2022
47(1)
PubMed ID: 34738627
DOI: 10.3892/or.2021.8216
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20513
Kono M, Komatsuda H, Yamaki H, Kumai T, Hayashi R, Wakisaka R, Nagato T, Ohkuri T, Kosaka A, Ohara K, Kishibe K, Takahara M, Katada A, Hayashi T, Kobayashi H, Harabuchi Y.
Immunomodulation via FGFR inhibition augments FGFR1 targeting T-cell based antitumor immunotherapy for head and neck squamous cell carcinoma.
Oncoimmunology
2022
11(1):2021619
PubMed ID: 35003900
DOI: 10.1080/2162402X.2021.2021619
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20544
Matsuda R, Sakagami H, Amano S, Iijima Y, Sano M, Uesawa Y, Tamura N, Oishi Y, Takeshima H.
Inhibition of Neurotoxicity/Anticancer Activity of Bortezomib by Caffeic Acid and Chlorogenic Acid.
Anticancer Res
2022
42(2):781-790
PubMed ID: 35093876
DOI: 10.21873/anticanres.15536
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16180
Katsuhiro Asaka, Akira Fukatsu, Chiaki Komine
The Effectiveness of a Portable Fluorescence Spectrophotometer for Early Detection of Oral Cancer
Open Journal of Stomatology
2022
12:30-31
DOI: 10.4236/ojst.2022.121003
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16203
Sasabe E, Tomomura A, Liu H, Sento S, Kitamura N, Yamamoto T.
Epidermal growth factor/epidermal growth factor receptor signaling blockage inhibits tumor cell-derived exosome uptake by oral squamous cell carcinoma through macropinocytosis
Cancer Sci
2022
113(2):609-621
PubMed ID: 34874595
DOI: 10.1111/cas.15225
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20648
Naitoh K, Orihara Y, Sakagami H, Miura T, Satoh K, Amano S, Bandow K, Iijima Y, Kurosaki K, Uesawa Y, Hashimoto M, Wakabayashi H.
Tumor-Specificity, Neurotoxicity, and Possible Involvement of the Nuclear Receptor Response Pathway of 4,6,8-Trimethyl Azulene Amide Derivatives.
Int J Mol Sci
2022
23(5)
PubMed ID: 35269748
DOI: 10.3390/ijms23052601
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20815
Hossain M, Roayapalley PK, Sakagami H, Satoh K, Bandow K, Das U, Dimmock JR.
Dichloroacetyl Amides of 3,5-Bis(benzylidene)-4-piperidones Displaying Greater Toxicity to Neoplasms than to Non-Malignant Cells.
Medicines (Basel)
2022
9(6)
PubMed ID: 35736248
DOI: 10.3390/medicines9060035
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17100
Izumi A, Yamamoto K, Kawaguchi M, Yamashita F, Fukushima T, Kiwaki T, Tanaka H, Yamashita Y, Kataoka H.
Insufficiency of hepatocyte growth factor activator inhibitor-1 confers lymphatic invasion of tongue carcinoma cells
Cancer Sci
2022
113(6):2179-2193
PubMed ID: 35332604
DOI: 10.1111/cas.15346
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20884
Shindo A, Kusano M, Sakagami H, Amano S, Inomata M, Abe M, Okazawa M, Ooka T.
Comparison of UVC Sensitivity and Dectin-2 Expression Between Malignant and Non-malignant Cells.
In Vivo
2022
36(5):2116-2125
PubMed ID: 36099100
DOI: 10.21873/invivo.12937
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20932
Katase N, Nishimatsu SI, Yamauchi A, Okano S, Fujita S.
Establishment of anti-DKK3 peptide for the cancer control in head and neck squamous cell carcinoma (HNSCC).
Cancer Cell Int
2022
22(1):352
PubMed ID: 36376957
DOI: 10.1186/s12935-022-02783-9
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20970
Murakami K, Umemura N, Adachi M, Motoki M, Ohkoshi E.
ABCG2, CD44 and SOX9 are increased with the acquisition of drug resistance and involved in cancer stem cell activities in head and neck squamous cell carcinoma cells.
Exp Ther Med
2022
24(6):722
PubMed ID: 36340608
DOI: 10.3892/etm.2022.11658
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20085
Kase Y, Uzawa K, Wagai S, Yoshimura S, Yamamoto JI, Toeda Y, Okubo M, Eizuka K, Ando T, Nobuchi T, Kawasaki K, Saito T, Iyoda M, Nakashima D, Kasamatsu A, Tanzawa H.
Engineered exosomes delivering specific tumor-suppressive RNAi attenuate oral cancer progression.
Sci Rep
2021
11(1):5897
PubMed ID: 33723306
DOI: 10.1038/s41598-021-85242-1
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20133
Nakamura A, Kakihara Y, Funayama A, Haga K, Mikami T, Kobayashi D, Yoshida Y, Izumi K, Kobayashi T, Saeki M.
HEATR1, a novel interactor of Pontin/Reptin, stabilizes Pontin/Reptin and promotes cell proliferation of oral squamous cell carcinoma.
Biochem Biophys Res Commun
2021
557:294-301
PubMed ID: 33894417
DOI: 10.1016/j.bbrc.2021.04.021
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14869
Torii C, Maishi N, Kawamoto T, Morimoto M, Akiyama K, Yoshioka Y, Minami T, Tsumita T, Alam MT, Ochiya T, Hida Y, Hida K.
miRNA-1246 in extracellular vesicles secreted from metastatic tumor induces drug resistance in tumor endothelial cells
Sci Rep
2021
11(1):13502
PubMed ID: 34226586
DOI: 10.1038/s41598-021-92879-5
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20350
Haga K, Yamazaki M, Maruyama S, Kawaharada M, Suzuki A, Hoshikawa E, Chan NN, Funayama A, Mikami T, Kobayashi T, Izumi K, Tanuma JI.
Crosstalk between oral squamous cell carcinoma cells and cancer-associated fibroblasts via the TGF-β/SOX9 axis in cancer progression.
Transl Oncol
2021
14(12):101236
PubMed ID: 34624685
DOI: 10.1016/j.tranon.2021.101236
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20406
Sawa C, Yofu S, Kiriyama K, Sutoh K, Saito T, Kishi S, Gunji M, Inoue Y, Sugi M, Shioda S, Honda K.
High concentration of extracellular nucleotides suppresses cell growth via delayed cell cycle progression in cancer and noncancer cell lines.
Heliyon
2021
7(11):e08318
PubMed ID: 34816032
DOI: 10.1016/j.heliyon.2021.e08318
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20438
Yang KH, Tang JY, Chen YN, Chuang YT, Tsai IH, Chiu CC, Li LJ, Chien TM, Cheng YB, Chang FR, Yen CY, Chang HW.
Nepenthes Extract Induces Selective Killing, Necrosis, and Apoptosis in Oral Cancer Cells.
J Pers Med
2021
11(9)
PubMed ID: 34575651
DOI: 10.3390/jpm11090871
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15868
Itashiki Y, Harada K, Takenawa T, Ferdous T, Ueyama Y, Mishima K.
Antitumor effects of bevacizumab in combination with fluoropyrimidine drugs on human oral squamous cell carcinoma
Oncol Lett
2021
22(4):730
PubMed ID: 34429770
DOI: 10.3892/ol.2021.12991
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16099
Saito K, Mitsui A, Sumardika IW, Yokoyama Y, Sakaguchi M, Kondo E.
PLOD2-driven IL-6/STAT3 signaling promotes the invasion and metastasis of oral squamous cell carcinoma via activation of integrin β1
Int J Oncol
2021
58(6):29
PubMed ID: 33887877
DOI: 10.3892/ijo.2021.5209
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16112
Akyu Takei R, Tomihara K, Yamazaki M, Moniruzzaman R, Heshiki W, Sekido K, Tachinami H, Sakurai K, Yonesi A, Imaue S, Fujiwara K, Noguchi M.
Protumor role of estrogen receptor expression in oral squamous cell carcinoma cells
Oral Surg Oral Med Oral Pathol Oral Radiol
2021
132(5):549-565
PubMed ID: 34518137
DOI: 10.1016/j.oooo.2021.04.006
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16136
Harada K, Ferdous T, Watanabe K, Mizukami Y, Mishima K.
Effects of an elemental diet, Elental®, may differ between healthy oral cells and oral cancer cells
Oncol Rep
2021
45(2):738-751
PubMed ID: 33416174
DOI: 10.3892/or.2020.7896
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16138
Ando T, Kasamatsu A, Kawasaki K, Hiroshima K, Fukushima R, Iyoda M, Nakashima D, Endo-Sakamoto Y, Uzawa K.
Tumor Suppressive Circular RNA-102450: Development of a Novel Diagnostic Procedure for Lymph Node Metastasis from Oral Cancer
Cancers (Basel)
2021
13(22):5708
PubMed ID: 34830863
DOI: 10.3390/cancers13225708
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16139
Kase-Kato I, Asai S, Minemura C, Tsuneizumi K, Oshima S, Koma A, Kasamatsu A, Hanazawa T, Uzawa K, Seki N.
Molecular Pathogenesis of the Coronin Family: CORO2A Facilitates Migration and Invasion Abilities in Oral Squamous Cell Carcinoma
Int J Mol Sci
2021
22(23):12684
PubMed ID: 34884487
DOI: 10.3390/ijms222312684
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16173
Suzuka J, Tsuda M, Wang L, Kohsaka S, Kishida K, Semba S, Sugino H, Aburatani S, Frauenlob M, Kurokawa T, Kojima S, Ueno T, Ohmiya Y, Mano H, Yasuda K, Gong JP, Tanaka S.
Rapid reprogramming of tumour cells into cancer stem cells on double-network hydrogels
Nat Biomed Eng
2021
5(8):914-925
PubMed ID: 33782572
DOI: 10.1038/s41551-021-00692-2
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16196
Sakagami H, Furukawa T, Satoh K, Amano S, Iijima Y, Koshikawa T, Asai D, Fukuchi K, Takemura H, Kanamoto T, Yokose S.
Re-Evaluation of Chemotherapeutic Potential of Pyoktanin Blue
Medicines (Basel)
2021
8(7):33
PubMed ID: 34206186
DOI: 10.3390/medicines8070033
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16206
Koma A, Asai S, Minemura C, Oshima S, Kinoshita T, Kikkawa N, Koshizuka K, Moriya S, Kasamatsu A, Hanazawa T, Uzawa K, Seki N.
Impact of Oncogenic Targets by Tumor-Suppressive miR-139-5p and miR-139-3p Regulation in Head and Neck Squamous Cell Carcinoma
Int J Mol Sci
2021
22(18):9947
PubMed ID: 34576110
DOI: 10.3390/ijms22189947
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16862
Kawasaki M, Sakabe T, Kodani I, Umekita Y.
Cytoplasmic-only Expression of Maspin Predicts Poor Prognosis in Patients With Oral Squamous Cell Carcinoma
Anticancer Res
2021
41(9):4563-4570
PubMed ID: 34475084
DOI: 10.21873/anticanres.15269
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16975
Hotta H, Hamamura K, Shibuya H, Ohmi Y, Furukawa K, Furukawa K.
Lewis y Expressed in Oral Squamous Cell Carcinoma Attenuates Malignant Properties via Down-regulation of EGF Signaling
Anticancer Res
2021
41(4):1821-1830
PubMed ID: 33813387
DOI: 10.21873/anticanres.14948
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11844
Sakurai K, Tomihara K, Yamazaki M, Heshiki W, Moniruzzaman R, Sekido K, Tachinami H, Ikeda A, Imaue S, Fujiwara K, Noguchi M.
CD36 expression on oral squamous cell carcinoma cells correlates with enhanced proliferation and migratory activity.
Oral Dis
2020
26(4):745-755
PubMed ID: 31603606
DOI: 10.1111/odi.13210
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11965
Fujii S, Tajiri Y, Hasegawa K, Matsumoto S, Yoshimoto RU, Wada H, Kishida S, Kido MA, Yoshikawa H, Ozeki S, Kiyoshima T.
The TRPV4-AKT axis promotes oral squamous cell carcinoma cell proliferation via CaMKII activation.
Lab. Invest.
2020
PubMed ID: 31857698
DOI: 10.1038/s41374-019-0357-z
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13013
Nakaya G, Sakagami H, Koga-Ogawa Y, Shiroto A, Nobesawa T, Ueda D, Nakatani S, Kobata K, Iijima Y, Tone S, David-Gonzalez A, Garcia-Contreras R, Tomomura M, Kito S, Tamura N, Takeshima H.
Augmentation of Neurotoxicity of Anticancer Drugs by X-Ray Irradiation.
In Vivo
2020
PubMed ID: 32354886
DOI: 10.21873/invivo.11869
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13093
Iijima Y, Bandow K, Amano S, Sano M, Hino S, Kaneko T, Horie N, Sakagami H.
Protection of Bortezomib-induced Neurotoxicity by Antioxidants.
Anticancer Res
2020
PubMed ID: 32620607
DOI: 10.21873/anticanres.14357
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13148
Tang JY, Wu KH, Wang YY, Farooqi AA, Huang HW, Yuan SF, Jian RI, Tsao LY, Chen PA, Chang FR, Cheng YB, Hu HC, Chang HW.
Methanol Extract of Usnea barbata Induces Cell Killing, Apoptosis, and DNA Damage against Oral Cancer Cells through Oxidative Stress.
Antioxidants (Basel)
2020
PubMed ID: 32756347
DOI: 10.3390/antiox9080694
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13205
Teratani M, Nakamura S, Sakagami H, Fujise M, Hashimoto M, Okudaira N, Bandow K, Iijima Y, Nagai J, Uesawa Y, Wakabayashi H.
Antitumor Effects and Tumor-specificity of Guaiazulene-3-Carboxylate Derivatives Against Oral Squamous Cell Carcinoma In Vitro.
Anticancer Res
2020
PubMed ID: 32878776
DOI: 10.21873/anticanres.14491
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13401
Hayashi R, Nagato T, Kumai T, Ohara K, Ohara M, Ohkuri T, Hirata-Nozaki Y, Harabuchi S, Kosaka A, Nagata M, Yajima Y, Yasuda S, Oikawa K, Kono M, Kishibe K, Takahara M, Katada A, Hayashi T, Celis E, Harabuchi Y, Kobayashi H.
Expression of placenta-specific 1 and its potential for eliciting anti-tumor helper T-cell responses in head and neck squamous cell carcinoma.
Oncoimmunology
2020
PubMed ID: 33457076
DOI: 10.1080/2162402X.2020.1856545
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13783
Otsuki Y, Yamasaki J, Suina K, Okazaki S, Koike N, Saya H, Nagano O.
Vasodilator oxyfedrine inhibits aldehyde metabolism and thereby sensitizes cancer cells to xCT-targeted therapy
Cancer Sci
2020
111(1):127-136.
PubMed ID: 31692172
DOI: 10.1111/cas.14224
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13892
Nguyen CTK, Sawangarun W, Mandasari M, Morita KI, Harada H, Kayamori K, Yamaguchi A, Sakamoto K.
AIRE is induced in oral squamous cell carcinoma and promotes cancer gene expression
PLoS One
2020
15(2):e0222689
PubMed ID: 32012175
DOI: 10.1371/journal.pone.0222689
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13903
Aika Tanzawa et al.
Comprehensive gene expression analysis of semaphorins in oral squamous cell carcinoma
Oral Science International
2020
17(2):67-72
DOI: 10.1002/osi2.1044
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13920
Kazutaka KIMURA, Yuichi OHNISHI, Tomoharu OKAMURA, Kazuya TOMINAGA, Masahiro NAKAJIMA
Effect of HGF/c-Met pathway in oral squamous cell carcinoma on EMT and metastatic potential
Journal of Osaka Dental University
2020
54(1):135-144
DOI: 10.18905/jodu.54.1_135
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10691
Iwai S, Kishimoto S, Amano Y, Nishiguchi A, Matsusaki M, Takeshita A, Akashi M.
Three-dimensional cultured tissue constructs that imitate human living tissue organization for analysis of tumor cell invasion.
J Biomed Mater Res A
2019
107(2):292-300
PubMed ID: 29280265
DOI: 10.1002/jbm.a.36319
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11300
Shimizu R, Ibaragi S, Eguchi T, Kuwajima D, Kodama S, Nishioka T, Okui T, Obata K, Takabatake K, Kawai H, Ono K, Okamoto K, Nagatsuka H, Sasaki A.
Nicotine promotes lymph node metastasis and cetuximab resistance in head and neck squamous cell carcinoma.
Int. J. Oncol.
2019
PubMed ID: 30431077
DOI: 10.3892/ijo.2018.4631
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11350
Katase N, Nishimatsu SI, Yamauchi A, Yamamura M, Fujita S.
DKK3 knockdown confers negative effects on the malignant potency of head and neck squamous cell carcinoma cells via the PI3K/Akt and MAPK signaling pathways.
Int. J. Oncol.
2019
PubMed ID: 30569110
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11354
Nakamura Y, Nakahata S, Kondo Y, Izumi A, Yamamoto K, Ichikawa T, Tamura T, Noumi K, Yamashita Y, Morishita K.
Overexpression of absent in melanoma 2 in oral squamous cell carcinoma contributes to tumor progression.
Biochem. Biophys. Res. Commun.
2019
PubMed ID: 30587341
DOI: 10.1016/j.bbrc.2018.12.066
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6020
Matsuo K, Suzuki H, Yatagai N, Enomoto Y, Kitayama M, Shigeoka M, Kimoto A, Matsumoto K, Komori T.
Red LED Light Is Influenced by IL-6 to Promote the Migration Ability of Oral Squamous Cell Carcinoma Cell Line.
Kobe J Med Sci
2019
64(6):E210-E216
PubMed ID: 31327864
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11584
Tang JY, Peng SY, Cheng YB, Wang CL, Farooqi AA, Yu TJ, Hou MF, Wang SC, Yen CH, Chan LP, Ou-Yang F, Chang HW.
Ethyl acetate extract of Nepenthes adrianii x clipeata induces antiproliferation, apoptosis, and DNA damage against oral cancer cells through oxidative stress.
Environ. Toxicol.
2019
PubMed ID: 31157515
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11590
Tang JY, Li LJ, Ou-Yang F, Wang CL, Shu CW, Wu KH, Wang HR, Yen CH, Cheng YB, Chang HW.
Ethyl Acetate Extract of Nepenthes ventricosa x maxima Exerts Preferential Killing to Oral Cancer Cells.
DNA Cell Biol.
2019
PubMed ID: 31170002
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11620
Imanari K, Hashimoto M, Wakabayashi H, Okudaira N, Bandow K, Nagai J, Tomomura M, Tomomura A, Uesawa Y, Sakagami H.
Quantitative Structure-Cytotoxicity Relationship of Azulene Amide Derivatives.
Anticancer Res.
2019
PubMed ID: 31262875
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11759
Uzawa K, Amelio AL, Kasamatsu A, Saito T, Kita A, Fukamachi M, Sawai Y, Toeda Y, Eizuka K, Hayashi F, Kato-Kase I, Sunohara M, Iyoda M, Koike K, Nakashima D, Ogawara K, Endo-Sakamoto Y, Shiiba M, Takiguchi Y, Yamauchi M, Tanzawa H.
Resveratrol Targets Urokinase-Type Plasminogen Activator Receptor Expression to Overcome Cetuximab-Resistance in Oral Squamous Cell Carcinoma.
Sci Rep
2019
PubMed ID: 31434965
DOI: 10.1038/s41598-019-48717-w
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9696
Kazuya Hiroshima, Masashi Shiiba, Noritoshi Oka, Fumihiko Hayashi, Sho Ishida, Reo Fukushima, Kazuyuki Koike, Manabu Iyoda, Dai Nakashima, Hideki Tanzawa, Katsuhiro Uzawa
Tspan15 Plays a Crucial Role in Metastasis in Oral Squamous Cell Carcinoma
Exp Cell Res
2019
384(2):111622
PubMed ID: 31518558
DOI: 10.1016/j.yexcr.2019.111622
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9810
Junko Shibato, Fumiko Takenoya, Takahiro Hirabayashi, Ai Kimura, Yusuke Iwasaki, Yoko Toyoda, Motohide Hori, Shigeru Tamogami, Randeep Rakwal, Seiji Shioda
Towards Identification of Bioactive Compounds in Cold Vacuum Extracted Double Cherry Blossom (Gosen-Sakura) Leaves
Plant Signal Behav
2019
14(10):e1644594
PubMed ID: 31342859
DOI: 10.1080/15592324.2019.1644594
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9890
Noritoshi Oka, Atsushi Kasamatsu, Yosuke Endo-Sakamoto, Keitaro Eizuka, Sho Wagai, Nao Koide-Ishida, Isao Miyamoto, Manabu Iyoda, Hideki Tanzawa, Katsuhiro Uzawa
Centromere Protein N Participates in Cellular Proliferation of Human Oral Cancer by Cell-Cycle Enhancement
J Cancer
2019
10(16):3728-3734
PubMed ID: 31333790
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11907
Cervino G, Fiorillo L, Herford AS, Romeo U, Bianchi A, Crimi S, D'Amico C, De Stefano R, Troiano G, Santoro R, Laino L, Laino G, Cicciù M.
Molecular Biomarkers Related to Oral Carcinoma: Clinical Trial Outcome Evaluation in a Literature Review.
Dis. Markers
2019
PubMed ID: 31019584
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11931
Iijima Y, Bandow K, Sano M, Hino S, Kaneko T, Horie N, Sakagami H.
In Vitro Assessment of Antitumor Potential and Combination Effect of Classical and Molecular-targeted Anticancer Drugs.
Anticancer Res.
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PubMed ID: 31810932
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11933
Nagai J, Shi H, Sezaki N, Yoshida N, Bandow K, Uesawa Y, Sakagami H, Tomomura M, Tomomura A, Takao K, Sugita Y.
Quantitative Structure-Cytotoxicity Relationship of 2-Arylazolylchromones and 2-Triazolylchromones.
Anticancer Res.
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PubMed ID: 31810912
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12457
Eizuka K, Nakashima D, Oka N, Wagai S, Takahara T, Saito T, Koike K, Kasamatsu A, Shiiba M, Tanzawa H, Uzawa K.
SYT12 plays a critical role in oral cancer and may be a novel therapeutic target
J Cancer
2019
10(20):4913-4920
PubMed ID: 31598163
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Krishnan NM, Katoh H, Palve V, Pareek M, Sato R, Ishikawa S, Panda B.
Functional genomics screen with pooled shRNA library and gene expression profiling with extracts of Azadirachta indica identify potential pathways for therapeutic targets in head and neck squamous cell carcinoma
PeerJ
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12460
Nozaki M, Yabuta N, Fukuzawa M, Mukai S, Okamoto A, Sasakura T, Fukushima K, Naito Y, Longmore GD, Nojima H.
LATS1/2 kinases trigger self-renewal of cancer stem cells in aggressive oral cancer
Oncotarget
2019
10(10):1014-1030
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12586
Sato K, Shi L, Ito F, Ohara Y, Motooka Y, Tanaka H, Mizuno M, Hori M, Hirayama T, Hibi H, Toyokuni S.
Non-thermal plasma specifically kills oral squamous cell carcinoma cells in a catalytic Fe(II)-dependent manner
J Clin Biochem Nutr
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65(1):8-15
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10649
Koshizuka K, Hanazawa T, Kikkawa N, Katada K, Okato A, Arai T, Idichi T, Osako Y, Okamoto Y, Seki N.
Antitumor miR-150-5p and miR-150-3p inhibit cancer cell aggressiveness by targeting SPOCK1 in head and neck squamous cell carcinoma.
Auris Nasus Larynx
2018
45:854-865
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10664
Ohnishi Y, Yasui H, Nozaki M, Nakajima M.
Molecularly-targeted therapy for the oral cancer stem cells.
Jpn Dent Sci Rev
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54:88-103
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10668
Ikehata N, Takanashi M, Satomi T, Watanabe M, Hasegawa O, Kono M, Enomoto A, Chikazu D, Kuroda M.
Toll-like receptor 2 activation implicated in oral squamous cell carcinoma development.
Biochem. Biophys. Res. Commun.
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495:2227-2234
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10724
Uesawa Y, Sakagami H, Okudaira N, Toda K, Takao K, Kagaya H, Sugita Y.
Quantitative Structure-Cytotoxicity Relationship of Cinnamic Acid Phenetyl Esters.
Anticancer Res.
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Okubo Y, Kasamatsu A, Yamatoji M, Fushimi K, Ishigami T, Shimizu T, Kasama H, Shiiba M, Tanzawa H, Uzawa K.
Diacylglycerol lipase alpha promotes tumorigenesis in oral cancer by cell-cycle progression.
Exp. Cell Res.
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In Vivo
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Hara Y, Sakagami H, Shi H, Abe T, Tamura N, Takeshima H, Horie N, Kaneko T, Shiratsuchi H, Kaneko T.
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In Vivo
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J Cancer
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Mol Clin Oncol
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Clin Exp Dent Res
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Lab Invest
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PLoS One
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9(12):e114121
PubMed ID: 25437003
DOI: 10.1371/journal.pone.0114121
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5544
Shimada C, Uesawa Y, Ishihara M, Kagaya H, Kanamoto T, Terakubo S, Nakashima H, Takao K, Saito T, Sugita Y, Sakagami H.
Quantitative structure-cytotoxicity relationship of phenylpropanoid amides.
Anticancer Res
2014
34(7):3543-8
PubMed ID: 24982367
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5337
Shimada C, Uesawa Y, Ishihara M, Kagaya H, Kanamoto T, Terakubo S, Nakashima H, Takao K, Miyashiro T, Sugita Y, Sakagami H.
Quantitative structure-cytotoxicity relationship of piperic acid amides.
Anticancer Res
2014
34(9):4877-84
PubMed ID: 25202069
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5315
Sekine S, Shimodaira C, Uesawa Y, Kagaya H, Kanda Y, Ishihara M, Amano O, Sakagami H, Wakabayashi H.
Quantitative structure-activity relationship analysis of cytotoxicity and anti-UV activity of 2-aminotropones.
Anticancer Res
2014
4(4):1743-50
PubMed ID: 24692705
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5307
Kumai T, Oikawa K, Aoki N, Kimura S, Harabuchi Y, Celis E, Kobayashi H.
Tumor-derived TGF-β and prostaglandin E2 attenuate anti-tumor immune responses in head and neck squamous cell carcinoma treated with EGFR inhibitor.
J Transl Med
2014
12:265
PubMed ID: 25240937
DOI: 10.1186/s12967-014-0265-3
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5122
Iida S, Shimada J, Sakagami H.
Cytotoxicity induced by docetaxel in human oral squamous cell carcinoma cell lines.
In Vivo
2013
27(3):321-32
PubMed ID: 23606687
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5110
Ohno H, Araho D, Uesawa Y, Kagaya H, Ishihara M, Sakagami H, Yamamoto M.
Evaluation of cytotoxiciy and tumor-specificity of licorice flavonoids based on chemical structure.
Anticancer Res
2013
33(8):3061-8
PubMed ID: 23898061
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5057
Tsujikawa T, Yaguchi T, Ohmura G, Ohta S, Kobayashi A, Kawamura N, Fujita T, Nakano H, Shimada T, Takahashi T, Nakao R, Yanagisawa A, Hisa Y, Kawakami Y.
Autocrine and paracrine loops between cancer cells and macrophages promote lymph node metastasis via CCR4/CCL22 in head and neck squamous cell carcinoma.
Int J Cancer.
2013
132(12):2755-66
PubMed ID: 23180648
DOI: 10.1002/ijc.27966
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6070
Yamamoto A, Kasamatsu A, Ishige S, Koike K, Saito K, Kouzu Y, Koike H, Sakamoto Y, Ogawara K, Shiiba M, Tanzawa H, Uzawa K.
Exocyst complex component Sec8: a presumed component in the progression of human oral squamous-cell carcinoma by secretion of matrix metalloproteinases.
J Cancer Res Clin Oncol
2013
139(4):533-42
PubMed ID: 23207790
DOI: 10.1007/s00432-012-1356-2
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6071
Kondoh M, Ohga N, Akiyama K, Hida Y, Maishi N, Towfik AM, Inoue N, Shindoh M, Hida K.
Hypoxia-induced reactive oxygen species cause chromosomal abnormalities in endothelial cells in the tumor microenvironment.
PLoS One
2013
8(11):e80349
PubMed ID: 24260373
DOI: 10.1371/journal.pone.0080349
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6072
Uchida F, Uzawa K, Kasamatsu A, Takatori H, Sakamoto Y, Ogawara K, Shiiba M, Bukawa H, Tanzawa H.
Overexpression of CDCA2 in human squamous cell carcinoma: correlation with prevention of G1 phase arrest and apoptosis.
PLoS One
2013
8(2):e56381
PubMed ID: 23418564
DOI: 10.1371/journal.pone.0056381
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6076
Minakawa Y, Kasamatsu A, Koike H, Higo M, Nakashima D, Kouzu Y, Sakamoto Y, Ogawara K, Shiiba M, Tanzawa H, Uzawa K.
Kinesin family member 4A: a potential predictor for progression of human oral cancer.
PLoS One. 2
2013
8(12):e85951
PubMed ID: 24386490
DOI: 10.1371/journal.pone.0085951
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6077
Mikami T, Hada T, Chosa N, Ishisaki A, Mizuki H, Takeda Y. Author information
Expression of Wilms' tumor 1 (WT1) in oral squamous cell carcinoma.
J Oral Pathol Med
2013
42(2):133-9
PubMed ID: 22672247
DOI: 10.1111/j.1600-0714.2012.01182.x
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6078
Hotta H, Hamamura K, Yamashita K, Shibuya H, Tokuda N, Hashimoto N, Furukawa K, Yamamoto N, Hattori H, Toyokuni S, Ueda M, Furukawa K.
Lewis y antigen is expressed in oral squamous cell carcinoma cell lines and tissues, but disappears in the invasive regions leading to the enhanced malignant properties irrespective of sialyl-Lewis x.
Glycoconj J
2013
30(6):585-97
PubMed ID: 23242548
DOI: 10.1007/s10719-012-9458-2
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6081
Kimura R, Kasamatsu A, Koyama T, Fukumoto C, Kouzu Y, Higo M, Endo-Sakamoto Y, Ogawara K, Shiiba M, Tanzawa H, Uzawa K.
Glutamate acid decarboxylase 1 promotes metastasis of human oral cancer by β-catenin translocation and MMP7 activation.
BMC Cancer
2013
13:555
PubMed ID: 24261884
DOI: 10.1186/1471-2407-13-555
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6083
Kumai T, Matsuda Y, Oikawa K, Aoki N, Kimura S, Harabuchi Y, Celis E, Kobayashi H.
EGFR inhibitors augment antitumour helper T-cell responses of HER family-specific immunotherapy.
Br J Cancer
2013
109(8):2155-66
PubMed ID: 24045666
DOI: 10.1038/bjc.2013.577
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15086
Katase N, Lefeuvre M, Tsujigiwa H, Fujii M, Ito S, Tamamura R, Buery RR, Gunduz M, Nagatsuka H.
Knockdown of Dkk-3 decreases cancer cell migration and invasion independently of the Wnt pathways in oral squamous cell carcinoma‑derived cells
Oncol Rep
2013
29(4):1349-55
PubMed ID: 23354949
DOI: 10.3892/or.2013.2251
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7722
Kusumoto T, Hamada T, Yamada N, Nagata S, Kanmura Y, Houjou I, Kamikawa Y, Yonezawa S, Sugihara K.
Comprehensive epigenetic analysis using oral rinse samples: a pilot study.
J. Oral Maxillofac. Surg.
2012
70:1486-94
PubMed ID: 21821326
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Miyazaki Y, Inoue H, Kikuchi K, Ochiai K, Kusama K.
Activation-induced cytidine deaminase mRNA expression in oral squamous cell carcinoma-derived cell lines is upregulated by inflammatory cytokines.
J Oral Sci
2012
54(1):71-5
PubMed ID: 22466889
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6088
Baba T, Kawaguchi M, Fukushima T, Sato Y, Orikawa H, Yorita K, Tanaka H, Lin CY, Sakoda S, Kataoka H.
Loss of membrane-bound serine protease inhibitor HAI-1 induces oral squamous cell carcinoma cells' invasiveness.
J Pathol
2012
228(2):181-92
PubMed ID: 22262311
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6089
Inoue H, Miyazaki Y, Kikuchi K, Yoshida N, Ide F, Ohmori Y, Tomomura A, Sakashita H, Kusama K.
Podoplanin promotes cell migration via the EGF-Src-Cas pathway in oral squamous cell carcinoma cell lines.
J Oral Sci
2012
54(3):241-50
PubMed ID: 23047035
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Katase N, Lefeuvre M, Gunduz M, Gunduz E, Beder LB, Grenman R, Fujii M, Tamamura R, Tsujigiwa H, Nagatsuka H.
Absence of Dickkopf (Dkk)-3 protein expression is correlated with longer disease-free survival and lower incidence of metastasis in head and neck squamous cell carcinoma.
Oncol Lett
2012
3(2):273-280
PubMed ID: 22740894
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Inoue H, Miyazaki Y, Kikuchi K, Yoshida N, Ide F, Ohmori Y, Tomomura A, Sakashita H, Kusama K.
Podoplanin expression during dysplasia-carcinoma sequence in the oral cavity.
Tumour Biol
2012
33(1):183-94
PubMed ID: 22081310
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Harada T, Harada K, Ueyama Y.
The enhancement of tumor radioresponse by combined treatment with cepharanthine is accompanied by the inhibition of DNA damage repair and the induction of apoptosis in oral squamous cell carcinoma
Int J Oncol
2012
41(2):565-72
PubMed ID: 22664937
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7601
Uesawa Y, Mohri K, Kawase M, Ishihara M, Sakagami H.
Quantitative structure-activity relationship (QSAR) analysis of tumor-specificity of 1,2,3,4-tetrahydroisoquinoline derivatives.
Anticancer Res.
2011
31:4231-8
PubMed ID: 22199286
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Susuki D, Kimura S, Naganuma S, Tsuchiyama K, Tanaka T, Kitamura N, Fujieda S, Itoh H.
Regulation of microRNA expression by hepatocyte growth factor in human head and neck squamous cell carcinoma.
Cancer Sci.
2011
102:2164-71
PubMed ID: 21899661
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6109
Inoue H, Ohnishi Y, Nakajima M, Kakudo K, Nozaki M.
A novel function of EpCAM in oral squamous cell carcinoma cells under anchorage-independent conditions.
Int J Oncol
2011
39(6):1401-5
PubMed ID: 21785818
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6112
lHiroshi Inoue et al
Effects of a gamma secretase inhibitor on the proliferation and invasiveness of oral squamous cell carcinoma cell lines
Asian Journal of Oral and Maxillofacial Surgery
2011
23:1-6
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6116
Zhang T, Hamada K, Hyodo M, Itoh H, Tani K, Goda H, Nakashiro K, Hamakawa H.
Gene therapy for oral squamous cell carcinoma with IAI.3B promoter-driven oncolytic adenovirus-infected carrier cells.
Oncol Rep
2011
25(3):795-802
PubMed ID: 21206983
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6118
Suguru Dateoka, Yuichi Ohnishi, Kenji Kakudo
Synergistic anti-tumor effect of CDDP with CRM197, a specific inhibitor of HB-EGF, in oral cancer
Journal of Osaka Dental University
2011
45：31-36
DOI: 10.18905/jodu.45.1_31
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8085
Sakagami H, Zhou L, Kawano M, Thet MM, Tanaka S, Machino M, Amano S, Kuroshita R, Watanabe S, Chu Q, Wang QT, Kanamoto T, Terakubo S, Nakashima H, Sekine K, Shirataki Y, Zhang CH, Uesawa Y, Mohri K, Kitajima M, Oizumi H, Oizumi T.
Multiple biological complex of alkaline extract of the leaves of Sasa senanensis Rehder.
In Vivo
2010
24:735-43
PubMed ID: 20952742
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8383
Uemura N, Kodama S, Nomi N, Okamoto T, Suzuki M.
Correlation between anti-survivin antibody and survivin mRNA expression in head and neck cancer patients.
Acta Otolaryngol.
2010
130:959-65
PubMed ID: 20100132
DOI: 10.3109/00016480903555416
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5611
Wakabayashi H, Narita T, Suga A, Sakagami H.
Hormetic response of cultured normal and tumor cells to 2-aminotropone derivatives.
In Vivo
2010
24(1):39-44
PubMed ID: 20133973
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6120
Furuta H, Kondo Y, Nakahata S, Hamasaki M, Sakoda S, Morishita K.
NDRG2 is a candidate tumor-suppressor for oral squamous-cell carcinoma.
Biochem Biophys Res Commun
2010
391(4):1785-91
PubMed ID: 20045673
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6122
Nomi N, Kodama S, Suzuki M.
Toll-like receptor 3 signaling induces apoptosis in human head and neck cancer via survivin associated pathway.
Oncol Rep
2010
24(1):225-31
PubMed ID: 20514466
DOI: 10.3892/or_00000850
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6123
Yuji Miyazaki et al
Association of butyric acid produced by periodontopathic bacteria with progression of oral cancer
J Cancer Sci Ther
2010
2(2) :26-32
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13818
Kikuji Yamashita, Shine-Od Dalkhsuren, Tatsuo Ishikawa, Kaori Sumida, Jun Ishibashi, Hiroyoshi Hosokawa, Akemichi Ueno, Fumio Nasu, Seiichiro Kitamura
Far Infrared Ray Radiation Inhibits the Proliferation of A549, HSC3 and Sa3 Cancer Cells through Enhancing the Expression of ATF3 Gene
Journal of Electromagnetic Analysis and Applications
2010
2:382-394
DOI: 10.4236/jemaa.2010.26050
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6127
Hatano H, Takekawa F, Hashimoto K, Ishihara M, Kawase M, Qing C, Qin-Tao W, Sakagami H.
Tumor-specific cytotoxic activity of 1,2,3,4-tetrahydroisoquinoline derivatives against human oral squamous cell carcinoma cell lines.
Anticancer Res
2009
29(8):3079-86
PubMed ID: 19661319
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6128
Takano A, Hashimoto K, Ogawa M, Koyanagi J, Kurihara T, Wakabayashi H, Kikuchi H, Nakamura Y, Motohashi N, Sakagami H, Yamamoto K, Tanaka A.
Tumor-specific cytotoxicity and type of cell death induced by naphtho[2,3-b]furan-4,9-diones and related compounds in human tumor cell lines: relationship to electronic structure.
Anticancer Res
2009
29(1):455-64
PubMed ID: 19331186
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6129
Narita T, Suga A, Kobayashi M, Hashimoto K, Sakagami H, Motohashi N, Kurihara T, Wakabayashi H.
Tumor-specific cytotoxicity and type of cell death induced by benzo[b]cyclohept[e][1,4]oxazine and 2-aminotropone derivatives.
Anticancer Res
2009
29(4):1123-30
PubMed ID: 19414354
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6410
Danjoh I, Sone H, Noda N, Iimura E, Nagayoshi M, Saijo K, Hiroyama T, Nakamura Y.
Is parainfluenza virus a threatening virus for human cancer cell lines?
Hum Cell
2009
22(3):81-4
PubMed ID: 19624309
DOI: 10.1111/j.1749-0774.2009.00071.x
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6136
Okamura M, Shimada J, Sakagami H.
Comparative analysis of cell death induction by cisplatin and 5-FU in human oral squamous and hepatocellular carcinoma cell lines.
Anticancer Res
2008
28(1A):253-9
PubMed ID: 18383853
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6138
Murayama H, Miyahara K, Wakabayashi H, Kurihara T, Hashimoto K, Amano O, Kikuchi H, Nakamura Y, Kanda Y, Kunii S, Motohashi N, Sakagami H.
Tumor-specific cytotoxicity and type of cell death induced by benzocycloheptoxazines in human tumor cell lines.
Anticancer Res
2008
28(2A):1069-78
PubMed ID: 18507056
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6141
Nakamura E, Kozaki K, Tsuda H, Suzuki E, Pimkhaokham A, Yamamoto G, Irie T, Tachikawa T, Amagasa T, Inazawa J, Imoto I.
Frequent silencing of a putative tumor suppressor gene melatonin receptor 1 A (MTNR1A) in oral squamous-cell carcinoma.
Cancer Sci
2008
99(7):1390-400
PubMed ID: 18452558
DOI: 10.1111/j.1349-7006.2008.00838.x
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6143
Sekine T, Takahashi J, Nishishiro M, Arai A, Wakabayashi H, Kurihara T, Kobayashi M, Hashimoto K, Kikuchi H, Katayama T, Kanda Y, Kunii S, Motohashi N, Sakagami H.
Tumor-specificity and type of cell death induced by trihaloacetylazulenes in human tumor cell lines.
Anticancer Res.
2007
27(1A):133-43
PubMed ID: 17352225
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6148
Akatsu Y, Ohshima N, Yamagishi Y, Nishishiro M, Wakabayashi H, Kurihara T, Kikuchi H, Katayama T, Motohashi N, Shoji Y, Nakashima H, Sakagami H.
Apoptosis-inducing activity of trihaloacetylazulenes against human oral tumor cell lines.
Anticancer Res
2006
26(3A):1917-23
PubMed ID: 16827125
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6150
Ichwan SJ, Yamada S, Sumrejkanchanakij P, Ibrahim-Auerkari E, Eto K, Ikeda MA.
Defect in serine 46 phosphorylation of p53 contributes to acquisition of p53 resistance in oral squamous cell carcinoma cells.
Oncogene
2006
25(8):1216-24
PubMed ID: 16247456
DOI: 10.1038/sj.onc.1209158
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6152
Wakabayashi H, Nishishiro M, Arikawa S, Hashimoto K, Kikuchi H, Nishikawa H, Kurihara T, Terakubo S, Shoji Y, Nakashima H, Motohashi N, Sakagami H.
Cytotoxic activity of azulenequinones against human oral tumor cell lines.
Anticancer Res
2005
25(1A):305-12
PubMed ID: 15816552
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