User's Publication |
19963
Eguchi H, Yu Y, Matsunaga T, Yoshino Y, Ikari A.
Acrolein suppresses anticancer drug-induced toxicity mediated by activating claudin-1 and Nrf2 axis in a spheroid model of human lung squamous cell carcinoma cells
Toxicol Lett
2024
392:46-55
PubMed ID: 38142011
DOI: 10.1016/j.toxlet.2023.12.012
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21562
Evers A, Krah S, Demir D, Gaa R, Elter D, Schroeter C, Zielonka S, Rasche N, Dotterweich J, Knuehl C, Doerner A.
Engineering hydrophobicity and manufacturability for optimized biparatopic antibody-drug conjugates targeting c-MET.
MAbs
2024
16(1):2302386
PubMed ID: 38214660
DOI: 10.1080/19420862.2024.2302386
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21736
Thu YM, Suzawa K, Tomida S, Ochi K, Tsudaka S, Takatsu F, Date K, Matsuda N, Iwata K, Nakata K, Shien K, Yamamoto H, Okazaki M, Sugimoto S, Toyooka S.
PAI-1 mediates acquired resistance to MET-targeted therapy in non-small cell lung cancer.
PLoS One
2024
19(5):e0300644
PubMed ID: 38758826
DOI: 10.1371/journal.pone.0300644
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19544
Sumitomo R, Menju T, Shimazu Y, Toyazaki T, Chiba N, Miyamoto H, Hirayama Y, Nishikawa S, Tanaka S, Yutaka Y, Yamada Y, Nakajima D, Ohsumi A, Hamaji M, Sato A, Yoshizawa A, Huang CL, Haga H, Date H.
M2-like tumor-associated macrophages promote epithelial-mesenchymal transition through the transforming growth factor β/Smad/zinc finger e-box binding homeobox pathway with increased metastatic potential and tumor cell proliferation in lung squamous cell carcinoma
Cancer Sci
2023
114(12):4521-4534
PubMed ID: 37806311
DOI: 10.1111/cas.15987
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19984
Groothuis PG, Jacobs DCH, Hermens IAT, Damming D, Berentsen K, Mattaar-Hepp E, Stokman MEM, Boekel TV, Rouwette M, van der Vleuten MAJ, Sesink A, Dijcks FA, Coumans RGE, Schouten J, Glaudemans DH, Wijk DV, Blomenröhr M, Kappers WA, Ubink R, van der Lee MMC, Dokter WHA.
Preclinical Profile of BYON3521 Predicts an Effective and Safe MET Antibody-Drug Conjugate
Mol Cancer Ther
2023
22(6):765-777
PubMed ID: 37042205
DOI: 10.1158/1535-7163.MCT-22-0596
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21174
Alburquerque-Bejar JJ, Navajas-Chocarro P, Saigi M, Ferrero-Andres A, Morillas JM, Vilarrubi A, Gomez A, Mate JL, Munoz-Marmol AM, Romero OA, Blecua P, Davalos V, Esteller M, Pros E, Llabata P, Torres-Diz M, Esteve-Codina A, Sanchez-Cespedes M.
MYC activation impairs cell-intrinsic IFNγ signaling and confers resistance to anti-PD1/PD-L1 therapy in lung cancer.
Cell Rep Med
2023
PubMed ID: 37044092
DOI: 10.1016/j.xcrm.2023.101006
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21436
Takatsu F, Suzawa K, Tomida S, Thu YM, Sakaguchi M, Toji T, Ohki M, Tsudaka S, Date K, Matsuda N, Iwata K, Zhu Y, Nakata K, Shien K, Yamamoto H, Nakayama A, Okazaki M, Sugimoto S, Toyooka S.
Periostin secreted by cancer-associated fibroblasts promotes cancer progression and drug resistance in non-small cell lung cancer.
J Mol Med (Berl)
2023
PubMed ID: 37831111
DOI: 10.1007/s00109-023-02384-7
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21505
Sima L, Wang Z, Yu L, Hou Y, Zhao D, Luo B, Liao W, Liu X.
Discovery of LAH-1 as potent c-Met inhibitor for the treatment of non-small cell lung cancer.
J Enzyme Inhib Med Chem
2023
39(1):2286435
PubMed ID: 38078363
DOI: 10.1080/14756366.2023.2286435
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16733
Stern YE, Al-Ghabkari A, Monast A, Fiset B, Aboualizadeh F, Yao Z, Stagljar I, Walsh LA, Duhamel S, Park M.
Met-HER3 crosstalk supports proliferation via MPZL3 in MET-amplified cancer cells
Cell Mol Life Sci
2022
79(3):178
PubMed ID: 35249128
DOI: 10.1007/s00018-022-04149-w
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16830
Sumiya R, Terayama M, Hagiwara T, Nakata K, Sekihara K, Nagasaka S, Miyazaki H, Igari T, Yamada K, Kawamura YI.
Loss of GSTO2 contributes to cell growth and mitochondria function via the p38 signaling in lung squamous cell carcinoma
Cancer Sci
2022
113(1):195-204
PubMed ID: 34726807
DOI: 10.1111/cas.15189
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22229
Gombodorj N, Yokobori T, Mutsuki N, Erkhem-Ochir B, Okami H, Asao T, Saeki H, Shirabe K, Yamanouchi D.
Effects of Ultrafine Single-Nanometer Oxygen Bubbles on Radiation Sensitivity in a Tumor-Bearing Mouse Model
Int J Mol Sci
2022
23(12):6838
PubMed ID: 35743281
DOI: 10.3390/ijms23126838
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13332
Hase H, Aoki M, Matsumoto K, Nakai S, Nagata T, Takeda A, Ueda K, Minami K, Kitae K, Jingushi K, Ueda Y, Yamamoto M, Furukawa T, Sato M, Tsujikawa K.
Cancer type‑SLCO1B3 promotes epithelial‑mesenchymal transition resulting in the tumour progression of non‑small cell lung cancer.
Oncol Rep
2021
PubMed ID: 33155667
DOI: 10.3892/or.2020.7839
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20043
Yuan G, Flores NM, Hausmann S, Lofgren SM, Kharchenko V, Angulo-Ibanez M, Sengupta D, Lu X, Czaban I, Azhibek D, Vicent S, Fischle W, Jaremko M, Fang B, Wistuba II, Chua KF, Roth JA, Minna JD, Shao NY, Jaremko Ł, Mazur PK, Gozani O.
Elevated NSD3 histone methylation activity drives squamous cell lung cancer.
Nature
2021
590(7846):504-508
PubMed ID: 33536620
DOI: 10.1038/s41586-020-03170-y
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14789
Chang A, Liu L, Ashby JM, Wu D, Chen Y, O'Neill SS, Huang S, Wang J, Wang G, Cheng D, Tan X, Petty WJ, Pasche BC, Xiang R, Zhang W, Sun P.
Recruitment of KMT2C/MLL3 to DNA Damage Sites Mediates DNA Damage Responses and Regulates PARP Inhibitor Sensitivity in Cancer
Cancer Res
2021
81(12):3358-3373
PubMed ID: 33853832
DOI: 10.1158/0008-5472.CAN-21-0688
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15499
Kosaka A, Yajima Y, Hatayama M, Ikuta K, Sasaki T, Hirai N, Yasuda S, Nagata M, Hayashi R, Harabuchi S, Ohara K, Ohara M, Kumai T, Ishibashi K, Hirata-Nozaki Y, Nagato T, Oikawa K, Harabuchi Y, Celis E, Okumura T, Ohsaki Y, Kobayashi H, Ohkuri T.
A stealth antigen SPESP1, which is epigenetically silenced in tumors, is a suitable target for cancer immunotherapy
Cancer Sci
2021
112(7):2705-2713
PubMed ID: 34009705
DOI: 10.1111/cas.14973
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16228
Joseph M. Gozgit, Melissa M. Vasbinder, Ryan P. Abo, Kaiko Kunii, Kristy G. Kuplast-Barr, Bin Gui, Alvin Z. Lu, Jennifer R. Molina, Elena Minissale, Kerren K. Swinger, Tim J. Wigle, Danielle J. Blackwell, Christina R. Majer, Yue Ren, Mario Niepel, Zacharenia A. Varsamis, Sunaina P. Nayak, Ellen Bamberg, Jan-Rung Mo, W. David Church, Ahmed S.A. Mady, Jeff Song, Luke Utley, Patricia E. Rao, Timothy J. Mitchison, Kevin W. Kuntz, Victoria M. Richon, Heike Keilhack
PARP7 negatively regulates the type I interferon response in cancer cells and its inhibition triggers antitumor immunity
Cancer Cell
2021
39(9):1214-1226.e10
PubMed ID: 34375612
DOI: 10.1016/j.ccell.2021.06.018
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16801
Minegishi K, Dobashi Y, Tsubochi H, Hagiwara K, Ishibashi Y, Nomura S, Nakamura R, Ohmoto Y, Endo S.
TFF-1 Functions to Suppress Multiple Phenotypes Associated with Lung Cancer Progression
Onco Targets Ther
2021
14:4761-4777
PubMed ID: 34531663
DOI: 10.2147/OTT.S322697
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12073
Haruna M, Hirata M, Iwahori K, Kanazawa T, Yamamoto Y, Goto K, Kawashima A, Morimoto-Okazawa A, Funaki S, Shintani Y, Kumanogoh A, Wada H.
Docetaxel Upregulates HMGB1 Levels in Non-small Cell Lung Cancer.
Biol. Pharm. Bull.
2020
PubMed ID: 32115500
DOI: 10.1248/bpb.b19-00702
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13401
Hayashi R, Nagato T, Kumai T, Ohara K, Ohara M, Ohkuri T, Hirata-Nozaki Y, Harabuchi S, Kosaka A, Nagata M, Yajima Y, Yasuda S, Oikawa K, Kono M, Kishibe K, Takahara M, Katada A, Hayashi T, Celis E, Harabuchi Y, Kobayashi H.
Expression of placenta-specific 1 and its potential for eliciting anti-tumor helper T-cell responses in head and neck squamous cell carcinoma.
Oncoimmunology
2020
PubMed ID: 33457076
DOI: 10.1080/2162402X.2020.1856545
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13773
Saigusa D, Motoike IN, Saito S, Zorzi M, Aoki Y, Kitamura H, Suzuki M, Katsuoka F, Ishii H, Kinoshita K, Motohashi H, Yamamoto M.
Impacts of NRF2 activation in non-small-cell lung cancer cell lines on extracellular metabolites
Cancer Sci
2020
111(2):667-678
PubMed ID: 31828882
DOI: 10.1111/cas.14278
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13841
Eguchi R, Wakabayashi I.
HDGF enhances VEGF‑dependent angiogenesis and FGF‑2 is a VEGF‑independent angiogenic factor in non‑small cell lung cancer
Oncol Rep
2020
44(1):14-28
PubMed ID: 32319650
DOI: 10.3892/or.2020.7580
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14799
Zenke FT, Zimmermann A, Sirrenberg C, Dahmen H, Kirkin V, Pehl U, Grombacher T, Wilm C, Fuchss T, Amendt C, Vassilev LT, Blaukat A.
Pharmacologic Inhibitor of DNA-PK, M3814, Potentiates Radiotherapy and Regresses Human Tumors in Mouse Models
Mol Cancer Ther
2020
19(5):1091-1101.
PubMed ID: 32220971
DOI: 10.1158/1535-7163.MCT-19-0734
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4183
Ohara K, Ohkuri T, Kumai T, Nagato T, Nozaki Y, Ishibashi K, Kosaka A, Nagata M, Harabuchi S, Ohara M, Oikawa K, Aoki N, Harabuchi Y, Celis E, Kobayashi H.
Targeting phosphorylated p53 to elicit tumor-reactive T helper responses against head and neck squamous cell carcinoma.
Oncoimmunology
2018
PubMed ID: 30510853
DOI: 10.1080/2162402X.2018.1466771
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4475
Iijima M, Gombodorj N, Tachibana Y, Tachibana K, Yokobori T, Honma K, Nakano T, Asao T, Kuwahara R, Aoyama K, Yasuda H, Kelly M, Kuwano H, Yamanouchi D.
Development of single nanometer-sized ultrafine oxygen bubbles to overcome the hypoxia-induced resistance to radiation therapy via the suppression of hypoxia-inducible factor‑1α.
Int. J. Oncol.
2018
52(3):679-686
PubMed ID: 29393397
DOI: 10.3892/ijo.2018.4248
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14222
Horie M, Kaczkowski B, Ohshima M, Matsuzaki H, Noguchi S, Mikami Y, Lizio M, Itoh M, Kawaji H, Lassmann T, Carninci P, Hayashizaki Y, Forrest ARR, Takai D, Yamaguchi Y, Micke P, Saito A, Nagase T.
Integrative CAGE and DNA Methylation Profiling Identify Epigenetically Regulated Genes in NSCLC
Mol Cancer Res
2017
15(10):1354-1365
PubMed ID: 28698358
DOI: 10.1158/1541-7786.MCR-17-0191
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14238
Ozono K, Ohishi Y, Onishi H, Nakamura K, Motoshita J, Kato M, Nakanishi R, Nakamura M, Oda Y.
Brain-derived neurotrophic factor/tropomyosin-related kinase B signaling pathway contributes to the aggressive behavior of lung squamous cell carcinoma
Lab Invest
2017
97(11):1332-1342
PubMed ID: 28604655
DOI: 10.1038/labinvest.2017.45
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14945
Togayachi A, Iwaki J, Kaji H, Matsuzaki H, Kuno A, Hirao Y, Nomura M, Noguchi M, Ikehara Y, Narimatsu H.
Glycobiomarker, Fucosylated Short-Form Secretogranin III Levels Are Increased in Serum of Patients with Small Cell Lung Carcinoma.
J Proteome Res
2017
16:4495-4505
PubMed ID: 28949141
DOI: 10.1021/acs.jproteome.7b00484
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9887
Ye X, Zhou Q, Matsumoto Y, Moriyama M, Kageyama S, Komatsu M, Satoh S, Tsuchida M, Saijo Y.
Inhibition of Glutaminolysis Inhibits Cell Growth via Down-regulating Mtorc1 Signaling in Lung Squamous Cell Carcinoma.
Anticancer Res.
2016
36:6021-6029
PubMed ID: 27793929
DOI: 10.21873/anticanres.11191
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9977
Sellmann C, Doerner A, Knuehl C, Rasche N, Sood V, Krah S, Rhiel L, Messemer A, Wesolowski J, Schuette M, Becker S, Toleikis L, Kolmar H, Hock B.
Balancing Selectivity and Efficacy of Bispecific Epidermal Growth Factor Receptor (EGFR) × c-MET Antibodies and Antibody-Drug Conjugates.
J. Biol. Chem.
2016
291:25106-25119
PubMed ID: 27694443
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12612
Yonesaka K, Hirotani K, Kawakami H, Takeda M, Kaneda H, Sakai K, Okamoto I, Nishio K, Jänne PA, Nakagawa K.
Anti-HER3 monoclonal antibody patritumab sensitizes refractory non-small cell lung cancer to the epidermal growth factor receptor inhibitor erlotinib
Oncogene
2016
35(7):878-86
PubMed ID: 25961915
DOI: 10.1038/onc.2015.142
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18948
Harada M, Kotake Y, Ohhata T, Kitagawa K, Niida H, Matsuura S, Funai K, Sugimura H, Suda T, Kitagawa M.
YB-1 promotes transcription of cyclin D1 in human non-small-cell lung cancers
Genes Cells
2014
19(6):504-16
PubMed ID: 24774443
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Fang WT, Fan CC, Li SM, Jang TH, Lin HP, Shih NY, Chen CH, Wang TY, Huang SF, Lee AY, Liu YL, Tsai FY, Huang CT, Yang SJ, Yen LJ, Chuu CP, Chen CY, Hsiung CA, Chang JY, Wang LH, Chang IS, Jiang SS.
Downregulation of a putative tumor suppressor BMP4 by SOX2 promotes growth of lung squamous cell carcinoma
Int J Cancer
2014
135(4):809-19
PubMed ID: 24477565
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Bladt F, Faden B, Friese-Hamim M, Knuehl C, Wilm C, Fittschen C, Grädler U, Meyring M, Dorsch D, Jaehrling F, Pehl U, Stieber F, Schadt O, Blaukat A.
EMD 1214063 and EMD 1204831 constitute a new class of potent and highly selective c-Met inhibitors.
Clin Cancer Res
2013
19(11):2941-51
PubMed ID: 23553846
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13951
Oshita H, Nishino R, Takano A, Fujitomo T, Aragaki M, Kato T, Akiyama H, Tsuchiya E, Kohno N, Nakamura Y, Daigo Y.
RASEF is a novel diagnostic biomarker and a therapeutic target for lung cancer
Mol Cancer Res
2013
11(8):937-51
PubMed ID: 23686708
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17162
Kimura M, Naito H, Tojo T, Itaya-Hironaka A, Dohi Y, Yoshimura M, Nakagawara K, Takasawa S, Taniguchi S.
REG Iα gene expression is linked with the poor prognosis of lung adenocarcinoma and squamous cell carcinoma patients via discrete mechanisms
Oncol Rep
2013
30(6):2625-31
PubMed ID: 24065141
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19029
Kanamori-Katayama M, Kaiho A, Ishizu Y, Okamura-Oho Y, Hino O, Abe M, Kishimoto T, Sekihara H, Nakamura Y, Suzuki H, Forrest AR, Hayashizaki Y.
LRRN4 and UPK3B are markers of primary mesothelial cells
PLoS One
2011
6(10):e25391
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16553
Hayashi S, Kumai T, Matsuda Y, Aoki N, Sato K, Kimura S, Kitada M, Tateno M, Celis E, Kobayashi H.
Six-transmembrane epithelial antigen of the prostate and enhancer of zeste homolog 2 as immunotherapeutic targets for lung cancer
J Transl Med
2011
9:191
PubMed ID: 22053850
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16149
Kayamori K, Sakamoto K, Nakashima T, Takayanagi H, Morita K, Omura K, Nguyen ST, Miki Y, Iimura T, Himeno A, Akashi T, Yamada-Okabe H, Ogata E, Yamaguchi A.
Roles of interleukin-6 and parathyroid hormone-related peptide in osteoclast formation associated with oral cancers: significance of interleukin-6 synthesized by stromal cells in response to cancer cells
Am J Pathol
2010
176(2):968-80
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Danjoh I, Sone H, Noda N, Iimura E, Nagayoshi M, Saijo K, Hiroyama T, Nakamura Y.
Is parainfluenza virus a threatening virus for human cancer cell lines?
Hum Cell
2009
22(3):81-4
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18311
Mitsuoka K, Miyoshi S, Kato Y, Murakami Y, Utsumi R, Kubo Y, Noda A, Nakamura Y, Nishimura S, Tsuji A.
Cancer detection using a PET tracer, 11C-glycylsarcosine, targeted to H+/peptide transporter
J Nucl Med
2008
49(4):615-22
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Matsuda Y, Yamamoto T, Kudo M, Kawahara K, Kawamoto M, Nakajima Y, Koizumi K, Nakazawa N, Ishiwata T, Naito Z.
Expression and roles of lumican in lung adenocarcinoma and squamous cell carcinoma
Int J Oncol
2008
33(6):1177-85
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19312
Yabuta N, Onda H, Watanabe M, Yoshioka N, Nagamori I, Funatsu T, Toji S, Tamai K, Nojima H.
Isolation and characterization of the TIGA genes, whose transcripts are induced by growth arrest
Nucleic Acids Res
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Konishi J, Yamazaki K, Yokouchi H, Shinagawa N, Iwabuchi K, Nishimura M.
The characteristics of human NKT cells in lung cancer--CD1d independent cytotoxicity against lung cancer cells by NKT cells and decreased human NKT cell response in lung cancer patients
Hum Immunol
2004
65(11):1377-88
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Togayachi A, Akashima T, Ookubo R, Kudo T, Nishihara S, Iwasaki H, Natsume A, Mio H, Inokuchi J, Irimura T, Sasaki K, Narimatsu H.
Molecular cloning and characterization of UDP-GlcNAc:lactosylceramide beta 1,3-N-acetylglucosaminyltransferase (beta 3Gn-T5), an essential enzyme for the expression of HNK-1 and Lewis X epitopes on glycolipids
J Biol Chem
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Bando T, Fujimura M, Kasahara K, Ueno T, Matsuda T.
Selective beta2-adrenoceptor agonist enhances sensitivity to cisplatin in non-small cell lung cancer cell line
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7(1):49-52
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Stimulation of beta-adrenoceptor enhances sensitivity to cisplatin in non-small cell lung cancer cell lines
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