細胞番号 : 細胞名
RCB1963 : VMRC-RCW
update : 2023/05/02
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| 細胞特性(Comment:英) | Human renal cell carcinoma cell line. TKG0447 (Deposited from Tohoku Univ.). |
| 細胞特性(日) | ヒト腎臓癌由来細胞株。 TKG0447 (東北大学医用細胞資源センターからの寄託)。 |
| 細胞特性(寄託者記述:英) | |
| 細胞特性(寄託者記述:日) | |
| 使用条件(英) | There is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC. |
| 使用条件(日) | 基礎的研究につきましては、使用制限はありません。商業利用や特許取得を目的とする場合は、事前に必ず理研細胞バンクに連絡をすること。 |
| 備考(英) | |
| 備考(日) | |
| 提供申込書類(英) |
Order Form(C-0005.pdf)
MTA(C-0007.pdf)
MTA(C-0007p.pdf)
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Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
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| 提供申込書類(日) |
依頼書C-0001.pdf
同意書(非営利学術目的)C-0003.pdf
同意書(営利目的)C-0003p.pdf
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提供同意書は、使用機関の種類や目的に応じて、非営利学術目的 (C-XXXX) と営利目的 (C-XXXXp) の2種類があります。該当する提供同意書をご使用ください（詳細）。特許等の取得及び商業利用等は事前に必ず cellbank.brc@riken.jp までご連絡ください。
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| 提供手数料 |
手数料とお支払いについてはこちらをご覧ください。 |
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細胞基本情報
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寄託者 |
Obinata, Masuo
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| 樹立者 |
Akiyama, M.
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| 寄託日 |
2004
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| 元の細胞 |
TKG0447
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| 動物種 |
human
< Mammals
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| 属名 |
Homo
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| 種名 |
sapiens
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| 採取組織 |
kidney
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| 病名 |
renal cell carcinoma
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| 細胞分類 |
cancer
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| 入手歴 |
Cell Resource Center for Biomedical Research, Tohoku University（TKG0447）
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|
細胞寿命 |
infinite
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| 細胞形態 |
epithelial-like
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| Cellosaurus(Expasy) |
CVCL_1790
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細胞培養・検査情報
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寄託時情報 |
ロット情報 |
| 培地・試薬情報 |
培地・試薬一覧はこちらをご覧ください。 |
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培養形態 |
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Adherent cells
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| 培地 |
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RPMI1640 + 10% FBS
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| 抗生物質 |
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Free
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継代方法 |
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0.25% Trypsin
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継代密度 |
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1 : 8 split
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| 継代・培地交換頻度 |
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Subculture : 2 times/week
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| 培養最適温度 |
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37
℃
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| 二酸化炭素濃度 |
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5
%
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| 凍結培地 |
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Medium + 10% DMSO
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| 凍結方法 |
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Slow freezing
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| マイコプラズマ |
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(-)
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| アイソザイム検査 |
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LD, NP
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| 個体識別検査 |
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OK
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| 画像情報 |
寄託時情報 | ロット情報 |
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| 文献情報 |
Reference(英) |
4件
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| Reference(日) |
0件
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| 利用者成果(英) |
11件
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| 利用者成果(日) |
0件
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| Reference(英) |
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3282
Emoto N, Isozaki O, Ohmura E, Ito F, Tsushima T, Shizume K, Demura H, Toma H
Basic fibroblast growth factor (FGF-2) in renal cell carcinoma, which is indistinguishable from that in normal kidney, is involved in renal cell carcinoma growth.
J Urol
1994
152:1626-31
PubMed ID: 7523715
DOI: 10.1016/s0022-5347(17)32492-8
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3285
Kitamura M, Shirasawa T, Mitarai T, Muramatsu T, Maruyama N
A retinoid responsive cytokine gene, MK, is preferentially expressed in the proximal tubules of the kidney and human tumor cell lines.
Am J Pathol
1993
142:425-31
PubMed ID: 8434639
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3284
Nishimura N, Kanda S, Yogi Y, Kawamura M, Nakamura M, Hyakutake H, Kanetake H, Saito Y
Secretion of autocrine growth-promoting activity by renal-carcinoma cells treated with 5-fluorouracil.
Int J Cancer
1992
52:105-9
PubMed ID: 1500215
DOI: 10.1002/ijc.2910520119
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3283
Ikemoto S, Hayahara N, Wada S, Nishio S, Maekawa M
Combined effect of tumor necrosis factor alpha and anticancer chemotherapeutic agents against human renal carcinoma cell lines.
Eur Urol
1991
19:236-9
PubMed ID: 1855530
DOI: 10.1159/000473628
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| 利用者成果(英) |
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10005
Soki Kashima, Takuya Maeda, Kyoko Masuda, Seiji Nagano, Takamitsu Inoue, Masashi Takeda, Yuka Kono, Takashi Kobayashi, Shigeyoshi Saito, Takahiro Higuchi, Hiroshi Ichise, Yuka Kobayashi, Keiko Iwaisako, Koji Terada, Yasutoshi Agata, Kazuyuki Numakura, Mitsuru Saito, Shintaro Narita, Masaki Yasukawa, Osamu Ogawa, Tomonori Habuchi, Hiroshi Kawamoto
Cytotoxic T Lymphocytes Regenerated From iPS Cells Have Therapeutic Efficacy in a Patient-Derived Xenograft Solid Tumor Model
iScience
2020
23(4):100998
PubMed ID: 32259478
DOI: 10.1016/j.isci.2020.100998
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11922
Isono T, Suzaki M.
Analysis of the characteristics of chemotherapy-resistant renal cell carcinomas based on global transcriptional analysis of their tissues and cell lines.
PLoS ONE
2019
PubMed ID: 31774870
DOI: 10.1371/journal.pone.0225721
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4371
Isono T, Chano T, Yoshida T, Kageyama S, Kawauchi A, Yonese J, Yuasa T.
Abundance of TRAIL attenuated by HIF2α and c-FLIP affects malignancy in renal cell carcinomas.
Oncotarget
2018
9(33):23091-23101
PubMed ID: 29796174
DOI: 10.18632/oncotarget.25214
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7050
Kajiura K, Masuda K, Naruto T, Kohmoto T, Watabnabe M, Tsuboi M, Takizawa H, Kondo K, Tangoku A, Imoto I.
Frequent silencing of the candidate tumor suppressor TRIM58 by promoter methylation in early-stage lung adenocarcinoma.
Oncotarget
2017
8:2890-2905
PubMed ID: 27926516
DOI: 10.18632/oncotarget.13761
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9731
Mizutani N, Abe M, Matsuoka S, Kajino K, Wakiya M, Ohtsuji N, Hatano R, Morimoto C, Hino O.
Establishment of anti-mesothelioma monoclonal antibodies.
BMC Res Notes
2016
9:324
PubMed ID: 27342200
DOI: 10.1186/s13104-016-2128-x
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9920
Isono T, Chano T, Yoshida T, Kageyama S, Kawauchi A, Suzaki M, Yuasa T.
Hydroxyl-HIF2-alpha is potential therapeutic target for renal cell carcinomas.
Am J Cancer Res
2016
6:2263-2276
PubMed ID: 27822416
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9921
Marichal T, Gaudenzio N, El Abbas S, Sibilano R, Zurek O, Starkl P, Reber LL, Pirottin D, Kim J, Chambon P, Roers A, Antoine N, Kawakami Y, Kawakami T, Bureau F, Tam SY, Tsai M, Galli SJ.
Guanine nucleotide exchange factor RABGEF1 regulates keratinocyte-intrinsic signaling to maintain skin homeostasis.
J. Clin. Invest.
2016
126:4497-4515
PubMed ID: 27820702
DOI: 10.1172/JCI86359
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6403
Terasaka N, Futai K, Katoh T, Suga H.
A human microRNA precursor binding to folic acid discovered by small RNA transcriptomic SELEX.
RNA
2016
22(12):1918-1928
PubMed ID: 27852928
DOI: 10.1261/rna.057737.116
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3744
Nakamura R, Oyama T, Tajiri R, Mizokami A, Namiki M, Nakamoto M, Ooi A.
Expression and regulatory effects on cancer cell behavior of NELL1 and NELL2 in human renal cell carcinoma.
Cancer Sci
2015
106(5):656-64
PubMed ID: 25726761
DOI: 10.1111/cas.12649
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6384
Hidenori Kawashima Sakae Masaki Marie Kawamura
Induction of HLA‑A* 33‑restricted cytotoxic lymphocytes against renal cell carcinoma targeting galectin 9 and PINCH
Biomedical Reports
2014
2:809-812
PubMed ID: 25279150
DOI: 10.3892/br.2014.334
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5012
Kawakami T, Chano T, Minami K, Okabe H, Okada Y, Okamoto K.
Imprinted DLK1 is a putative tumor suppressor gene and inactivated by epimutation at the region upstream of GTL2 in human renal cell carcinoma.
Hum Mol Genet
2006
15(6):821-30
PubMed ID: 16439445
DOI: 10.1093/hmg/ddl001
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