Cell No. : Cell Name
RCB1963 : VMRC-RCW
update : 2021/02/26
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Comment | Human renal cell carcinoma cell line. TKG0447 (Deposited from Tohoku Univ.). |
Comment from the depositor | |
Terms and conditions | There is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC. |
Remarks | |
Order Form |
Order Form(C-0005.pdf)
 
MTA(C-0007.pdf)
 
MTA(C-0007p.pdf)
 
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Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
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Basic information
|
Depositor |
Obinata, Masuo
|
Originator |
Akiyama, M.
|
Year of deposit |
2004
|
Original cell |
TKG0447
|
Animal |
_human
< Mammals
|
Genus |
Homo
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Species |
sapiens
|
Tissue |
kidney
|
Disease name |
renal cell carcinoma
|
Classification |
cancer
|
History |
Cell Resource Center for Biomedical Research, Tohoku University(TKG0447)
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|
Lifespan |
infinite
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Morphology |
epithelial-like
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deposit info |
lot info |
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Medium |
Medium List |
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Culture type |
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Adherent cells
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Medium and additives |
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RPMI1640 + 10% FBS
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Antibiotics |
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Free
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Passage method |
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0.25% trypsin
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Culture information
|
Passage ratio |
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1 : 8 split
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SC frequency |
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Subculture : 2 times/week
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Temperature |
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37
℃
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CO2 concentration |
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5
%
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Freeze medium |
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Medium + 10% DMSO
|
Freezing method |
|
Slow freezing
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Mycoplasma |
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(-)
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STR(human) |
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OK
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Isozyme |
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LD, NP
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Images |
deposit info | lot info |
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|
Reference information |
Reference |
4
|
User's Publication |
11
|
Reference |
3282
Emoto N, Isozaki O, Ohmura E, Ito F, Tsushima T, Shizume K, Demura H, Toma H
Basic fibroblast growth factor (FGF-2) in renal cell carcinoma, which is indistinguishable from that in normal kidney, is involved in renal cell carcinoma growth.
J Urol
1994
152:1626-31
PubMed ID: 7523715
|
3285
Kitamura M, Shirasawa T, Mitarai T, Muramatsu T, Maruyama N
A retinoid responsive cytokine gene, MK, is preferentially expressed in the proximal tubules of the kidney and human tumor cell lines.
Am J Pathol
1993
142:425-31
PubMed ID: 8434639
|
3284
Nishimura N, Kanda S, Yogi Y, Kawamura M, Nakamura M, Hyakutake H, Kanetake H, Saito Y
Secretion of autocrine growth-promoting activity by renal-carcinoma cells treated with 5-fluorouracil.
Int J Cancer
1992
52:105-9
PubMed ID: 1500215
|
3283
Ikemoto S, Hayahara N, Wada S, Nishio S, Maekawa M
Combined effect of tumor necrosis factor alpha and anticancer chemotherapeutic agents against human renal carcinoma cell lines.
Eur Urol
1991
19:236-9
PubMed ID: 1855530
|
User's Publication |
10005
Soki Kashima, Takuya Maeda, Kyoko Masuda, Seiji Nagano, Takamitsu Inoue, Masashi Takeda, Yuka Kono, Takashi Kobayashi, Shigeyoshi Saito, Takahiro Higuchi, Hiroshi Ichise, Yuka Kobayashi, Keiko Iwaisako, Koji Terada, Yasutoshi Agata, Kazuyuki Numakura, Mitsuru Saito, Shintaro Narita, Masaki Yasukawa, Osamu Ogawa, Tomonori Habuchi, Hiroshi Kawamoto
Cytotoxic T Lymphocytes Regenerated From iPS Cells Have Therapeutic Efficacy in a Patient-Derived Xenograft Solid Tumor Model
iScience
2020
23(4):100998
PubMed ID: 32259478
|
11922
Isono T, Suzaki M.
Analysis of the characteristics of chemotherapy-resistant renal cell carcinomas based on global transcriptional analysis of their tissues and cell lines.
PLoS ONE
2019
PubMed ID: 31774870
|
4371
Isono T, Chano T, Yoshida T, Kageyama S, Kawauchi A, Yonese J, Yuasa T.
Abundance of TRAIL attenuated by HIF2α and c-FLIP affects malignancy in renal cell carcinomas.
Oncotarget
2018
9(33):23091-23101
PubMed ID: 29796174
|
7050
Kajiura K, Masuda K, Naruto T, Kohmoto T, Watabnabe M, Tsuboi M, Takizawa H, Kondo K, Tangoku A, Imoto I.
Frequent silencing of the candidate tumor suppressor TRIM58 by promoter methylation in early-stage lung adenocarcinoma.
Oncotarget
2017
8:2890-2905
PubMed ID: 27926516
|
9731
Mizutani N, Abe M, Matsuoka S, Kajino K, Wakiya M, Ohtsuji N, Hatano R, Morimoto C, Hino O.
Establishment of anti-mesothelioma monoclonal antibodies.
BMC Res Notes
2016
9:324
PubMed ID: 27342200
|
9920
Isono T, Chano T, Yoshida T, Kageyama S, Kawauchi A, Suzaki M, Yuasa T.
Hydroxyl-HIF2-alpha is potential therapeutic target for renal cell carcinomas.
Am J Cancer Res
2016
6:2263-2276
PubMed ID: 27822416
|
9921
Marichal T, Gaudenzio N, El Abbas S, Sibilano R, Zurek O, Starkl P, Reber LL, Pirottin D, Kim J, Chambon P, Roers A, Antoine N, Kawakami Y, Kawakami T, Bureau F, Tam SY, Tsai M, Galli SJ.
Guanine nucleotide exchange factor RABGEF1 regulates keratinocyte-intrinsic signaling to maintain skin homeostasis.
J. Clin. Invest.
2016
126:4497-4515
PubMed ID: 27820702
|
6403
Terasaka N, Futai K, Katoh T, Suga H.
A human microRNA precursor binding to folic acid discovered by small RNA transcriptomic SELEX.
RNA
2016
22(12):1918-1928
PubMed ID: 27852928
|
3744
Nakamura R, Oyama T, Tajiri R, Mizokami A, Namiki M, Nakamoto M, Ooi A.
Expression and regulatory effects on cancer cell behavior of NELL1 and NELL2 in human renal cell carcinoma.
Cancer Sci
2015
106(5):656-64
PubMed ID: 25726761
|
6384
Hidenori Kawashima Sakae Masaki Marie Kawamura
Induction of HLA‑A* 33‑restricted cytotoxic lymphocytes against renal cell carcinoma targeting galectin 9 and PINCH
Biomedical Reports
2014
2:809-812
|
5012
Kawakami T, Chano T, Minami K, Okabe H, Okada Y, Okamoto K.
Imprinted DLK1 is a putative tumor suppressor gene and inactivated by epimutation at the region upstream of GTL2 in human renal cell carcinoma.
Hum Mol Genet
2006
15(6):821-30
PubMed ID: 16439445
|