CELL SEARCH SYSTEM -CELL BANK- (RIKEN BRC) [RCB1953 : NB-1]

細胞番号 : 細胞名
RCB1953 : NB-1 update : 2024/10/04

細胞特性(Comment:英)

Human cell line derived from neuroblastoma. Dibuty-cAMP (1 mM) induces differentiation. TKG0486 (Deposited from Tohoku Univ.).

細胞特性(日)

ヒト神経芽腫由来細胞株。Dibuty-cAMP (1 mM)で分化誘導可能。 TKG0486 (東北大学医用細胞資源センターからの寄託)。

細胞特性(寄託者記述:英)

細胞特性(寄託者記述:日)

使用条件(英)

There is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC.

使用条件(日)

基礎的研究につきましては、使用制限はありません。商業利用や特許取得を目的とする場合は、事前に必ず理研細胞バンクに連絡をすること。

備考(英)

備考(日)

提供申込書類(英)

Order Form(C-0005.pdf) MTA(C-0007.pdf) MTA(C-0007p.pdf)

Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).

提供申込書類(日)

依頼書C-0001.pdf 同意書(非営利学術目的)C-0003.pdf 同意書(営利目的)C-0003p.pdf

提供同意書は、使用機関の種類や目的に応じて、非営利学術目的 (C-XXXX) と営利目的 (C-XXXXp) の2種類があります。該当する提供同意書をご使用ください（詳細）。特許等の取得及び商業利用等は事前に必ず cellbank.brc@riken.jp までご連絡ください。

提供手数料

手数料とお支払いについてはこちらをご覧ください。

細胞基本情報

寄託者

Obinata, Masuo

樹立者

Miyake, S.

寄託日

2004

元の細胞

TKG0486

動物種

_human < Mammals

属名

Homo

種名

sapiens

性別

Male

齢

2 years

採取組織

sympatho adrenal cell

病名

neuroblastoma

細胞分類

cancer

入手歴

Cell Resource Center for Biomedical Research, Tohoku University (TKG0471)

細胞寿命

infinite

細胞形態

other

Cellosaurus(Expasy)

CVCL_1440

細胞培養・検査情報

寄託時情報

ロット情報

培地・試薬情報

培地・試薬一覧はこちらをご覧ください。

培養形態

Adherent cells

培地

(MEM : RPMI1640 = 1 : 1) + 10% FBS

抗生物質

Free

継代方法

0.25% Trypsin

継代密度

1 : 8 split

継代・培地交換頻度

Subculture : 2 times/week

培養最適温度

37 ℃

二酸化炭素濃度

5 %

凍結培地

Medium + 10% DMSO

凍結方法

Slow freezing

マイコプラズマ/アコレプラズマ

(-)

アイソザイム検査

LD, NP

個体識別検査

画像情報

寄託時情報

ロット情報

文献情報

Reference(英)

8件

Reference(日)

0件

利用者成果(英)

12件

利用者成果(日)

0件

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Reference(英)

3264 Andrich MP, Shalaby-Rana E, Movassaghi N, Majd M. The role of 131 iodine-metaiodobenzylguanidine scanning in the correlative imaging of patients with neuroblastoma. Pediatrics 1996 97:246-250 PubMed ID: 8584386

3265 Mastrangelo R, Tornesello A, Riccardi R, Lasorella A, Mastrangelo S, Mancini A, Rufini V, Troncone L A new approach in the treatment of stage IV neuroblastoma using a combination of [131I]meta-iodobenzylguanidine (MIBG) and cisplatin. Eur J Cancer 1995 31A:606-11 PubMed ID: 7576979 DOI: 10.1016/0959-8049(95)00048-n

3266 Kunimoto M Possible involvement of the 440 kDa isoform of ankyrinB in neuritogenesis in human neuroblastoma NB-1 cells. FEBS Lett 1995 357:217-20 PubMed ID: 7805894 DOI: 10.1016/0014-5793(94)01363-6

3263 Kunimoto M, Suzuki T Selective down-regulation of 440 kDa ankyrinB associated with neurite retraction. Neuroreport 1995 6:2545-8 PubMed ID: 8741759 DOI: 10.1097/00001756-199512150-00023

3261 Ohnuma N, Kasuga T, Nojiri I, Furuse T. Radiosensitivity of human neuroblastoma cell line (NB-1) Gann 1977 68:711-712 PubMed ID: 590688

1648 Ishikawa S Differentiation of human neuroblastoma cells in vitro--morphological changes induced by dibutyrl cyclic AMP. Acta Pathol Jpn 1977 27:697-711 PubMed ID: 201151 DOI: 10.1111/j.1440-1827.1977.tb00186.x

3259 Miyake S, Shimo Y, Kitamura T. Morphological differentiation in vitro of human continuous and functional neuroblastoma cell line, NB-I under treatment of (But)2cAMP (author's transl). Noshinkei Geka 1975 3:407-414 PubMed ID: 174024

3260 Imashuku S, Inui A, Nakamura T, Tanaka J, Miyake S. Catecholamine metabolism in tissue culture cells of a neuroblastoma. J Clin Endocrinol Metab 1973 36:931-936 PubMed ID: 4144593 DOI: 10.1210/jcem-36-5-931

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Reference(日)

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利用者成果(英)

19771 Guan J, Borenäs M, Xiong J, Lai WY, Palmer RH, Hallberg B. IGF1R Contributes to Cell Proliferation in ALK-Mutated Neuroblastoma with Preference for Activating the PI3K-AKT Signaling Pathway Cancers (Basel) 2023 15(17):4252 PubMed ID: 37686528 DOI: 10.3390/cancers15174252

17079 Müller M, Rösch L, Najafi S, Gatzweiler C, Ridinger J, Gerloff XF, Jones DTW, Baßler J, Kreth S, Stainczyk S, Frese K, Meder B, Westermann F, Milde T, Peterziel H, Witt O, Oehme I. Combining APR-246 and HDAC-Inhibitors: A Novel Targeted Treatment Option for Neuroblastoma Cancers (Basel) 2021 13(17):4476 PubMed ID: 34503286 DOI: 10.3390/cancers13174476

10780 Shen J, Najafi S, Stäble S, Fabian J, Koeneke E, Kolbinger FR, Wrobel JK, Meder B, Distel M, Heimburg T, Sippl W, Jung M, Peterziel H, Kranz D, Boutros M, Westermann F, Witt O, Oehme I. A kinome-wide RNAi screen identifies ALK as a target to sensitize neuroblastoma cells for HDAC8-inhibitor treatment. Cell Death Differ. 2018 25(12):2053-2070 PubMed ID: 29515255 DOI: 10.1038/s41418-018-0080-0

9465 Tomohiko Tokunaga, Takashi Ando, Miki Suzuki-Karasaki, Tomohisa Ito, Asuka Onoe-Takahashi, Toyoko Ochiai, Masayoshi Soma , Yoshihiro Suzuki-Karasaki Plasma-stimulated Medium Kills TRAIL-resistant Human Malignant Cells by Promoting Caspase-Independent Cell Death via Membrane Potential and Calcium Dynamics Modulation Int J Oncol 2018 52(3):697-708 PubMed ID: 29393427 DOI: 10.3892/ijo.2018.4251

10457 Watanabe Y, Ishizuka Y, Hirano T, Nagasaki-Maeoka E, Hoshi R, Yoshizawa S, Uekusa S, Kawashima H, Sugito K, Shinohara K, Fukuda N, Nagase H, Soma M, Koshinaga T, Fujiwara K. ZAR1 knockdown promotes the differentiation of human neuroblastoma cells by suppression of MYCN expression. Med. Oncol. 2017 34:158 PubMed ID: 28791558 DOI: 10.1007/s12032-017-0999-x

10480 Bingel C, Koeneke E, Ridinger J, Bittmann A, Sill M, Peterziel H, Wrobel JK, Rettig I, Milde T, Fernekorn U, Weise F, Schober A, Witt O, Oehme I. Three-dimensional tumor cell growth stimulates autophagic flux and recapitulates chemotherapy resistance. Cell Death Dis 2017 8:e3013 PubMed ID: 28837150 DOI: 10.1038/cddis.2017.398

7205 Indo HP, Tomiyoshi T, Suenaga S, Tomita K, Suzuki H, Masuda D, Terada M, Ishioka N, Gusev O, Cornette R, Okuda T, Mukai C, Majima HJ. MnSOD downregulation induced by extremely low 0.1 mGy single and fractionated X-rays and microgravity treatment in human neuroblastoma cell line, NB-1. J Clin Biochem Nutr 2015 57:98-104 PubMed ID: 26388666 DOI: 10.3164/jcbn.15-20

18785 Sugito K, Kawashima H, Yoshizawa S, Uekusa S, Hoshi R, Furuya T, Kaneda H, Hosoda T, Konuma N, Masuko T, Ohashi K, Ikeda T, Koshinaga T, Tomita R, Shinojima Y, Fujiwara K, Watanabe T, Held WA, Nagase H. Non-promoter DNA hypermethylation of Zygote Arrest 1 (ZAR1) in neuroblastomas J Pediatr Surg 2013 48(4):782-8 PubMed ID: 23583134 DOI: 10.1016/j.jpedsurg.2012.08.008

18920 Nishio N, Fujita M, Tanaka Y, Maki H, Zhang R, Hirosawa T, Demachi-Okamura A, Uemura Y, Taguchi O, Takahashi Y, Kojima S, Kuzushima K. Zoledronate sensitizes neuroblastoma-derived tumor-initiating cells to cytolysis mediated by human γδ T cells J Immunother 2012 35(8):598-606 PubMed ID: 22996365 DOI: 10.1097/CJI.0b013e31826a745a

9499 Surasak Sangkhathat, Keigo Nara, Takeshi Kusafuka, Akihiro Yoneda, Masahiro Fukuzawa Artificially Accumulated Beta-Catenin Inhibits Proliferation and Induces Neurite Extension of Neuroblastoma Cell Line NB-1 via Up-Regulation of trkA Oncol Rep 2006 16(6):1197-203 PubMed ID: 17089037

3795 Yoshio Ishii, Hiro-omi Tamura Sulfoconjugation of Bisphenol A in a Human Neuroblastoma Cell Line, NB-1 Journal of Health Science 2003 49:319-323 DOI: 10.1248/jhs.49.319

2550 Tamura, H O, Taniguchi K, Hayashi E, Hiyoshi Y, Nagai F Expression profiling of sulfotransferases in human cell lines derived from extra-hepatic tissues. Biol Pharm Bull 2001 24:1258-62 PubMed ID: 11725959 DOI: 10.1248/bpb.24.1258

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