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19755
Matsuishi A, Nakajima S, Kaneta A, Saito K, Fukai S, Sakuma M, Tsumuraya H, Okayama H, Saito M, Mimura K, Nirei A, Kikuchi T, Hanayama H, Saze Z, Sakamoto W, Momma T, Kono K.
The tumor cell-intrinsic cGAS-STING pathway is associated with the high density of CD8+ T cells after chemotherapy in esophageal squamous cell carcinoma
Esophagus
2024
21(2):165-175
PubMed ID: 38324215
DOI: 10.1007/s10388-024-01044-0
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19698
Takashima Y, Komatsu S, Ohashi T, Kiuchi J, Nishibeppu K, Kamiya H, Arakawa H, Ishida R, Shimizu H, Arita T, Konishi H, Shiozaki A, Kubota T, Fujiwara H, Otsuji E.
Plasma miR-1254 as a predictive biomarker of chemosensitivity and a target of nucleic acid therapy in esophageal cancer
Cancer Sci
2023
114(7):3027-3040
PubMed ID: 37190912
DOI: 10.1111/cas.15830
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21175
Zhang X, Wang Y, Zhang X, Shen Y, Yang K, Ma Q, Qiao Y, Shi J, Wang Y, Xu L, Yang B, Ge G, Hu L, Kong X, Yang C, Chen Y, Ding J, Meng L.
Intact regulation of G1/S transition renders esophageal squamous cell carcinoma sensitive to PI3Kα inhibitors.
Signal Transduct Target Ther
2023
8(1):153
PubMed ID: 37041169
DOI: 10.1038/s41392-023-01359-x
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21406
Nguyen Vu TH, Kikuchi O, Ohashi S, Saito T, Ida T, Nakai Y, Cao Y, Yamamoto Y, Kondo Y, Mitani Y, Kataoka S, Kondo T, Katada C, Yamada A, Matsubara J, Muto M.
Combination therapy with WEE1 inhibition and trifluridine/tipiracil against esophageal squamous cell carcinoma.
Cancer Sci
2023
PubMed ID: 37724648
DOI: 10.1111/cas.15966
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17547
Shimizu H, Katsurahara K, Inoue H, Shiozaki A, Kosuga T, Kudou M, Arita T, Konishi H, Komatsu S, Fujiwara H, Morinaga Y, Konishi E, Otsuji E.
NADPH Oxidase 2 Has a Crucial Role in Cell Cycle Progression of Esophageal Squamous Cell Carcinoma
Ann Surg Oncol
2022
29(13):8677-8687
PubMed ID: 35972670
DOI: 10.1245/s10434-022-12384-5
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20614
Tsuchihashi K, Hirata Y, Yamasaki J, Suina K, Tanoue K, Yae T, Masuda K, Baba E, Akashi K, Kitagawa Y, Saya H, Nagano O.
Presence of spontaneous epithelial-mesenchymal plasticity in esophageal cancer.
Biochem Biophys Rep
2022
30:101246
PubMed ID: 35330672
DOI: 10.1016/j.bbrep.2022.101246
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20046
Mitsuda M, Shiozaki A, Kudou M, Shimizu H, Arita T, Kosuga T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, Otsuji E.
Functional Analysis and Clinical Significance of Chloride Channel 2 Expression in Esophageal Squamous Cell Carcinoma.
Ann Surg Oncol
2021
PubMed ID: 33565032
DOI: 10.1245/s10434-021-09659-8
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20071
Matsumoto Y, Shiozaki A, Kosuga T, Kudou M, Shimizu H, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, Otsuji E.
Expression and Role of CFTR in Human Esophageal Squamous Cell Carcinoma.
Ann Surg Oncol
2021
PubMed ID: 33710504
DOI: 10.1245/s10434-021-09752-y
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16116
Kobayashi T, Makino T, Yamashita K, Saito T, Tanaka K, Takahashi T, Kurokawa Y, Yamasaki M, Nakajima K, Morii E, Eguchi H, Doki Y.
APR-246 induces apoptosis and enhances chemo-sensitivity via activation of ROS and TAp73-Noxa signal in oesophageal squamous cell cancer with TP53 missense mutation
Br J Cancer
2021
125(11):1523-1532
PubMed ID: 34599296
DOI: 10.1038/s41416-021-01561-0
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16863
Takaki W, Konishi H, Shoda K, Arita T, Kataoka S, Shibamoto J, Furuke H, Takabatake K, Shimizu H, Komatsu S, Shiozaki A, Fujiwara H, Masuda K, Otsuji E.
Significance of Circular FAT1 as a Prognostic Factor and Tumor Suppressor for Esophageal Squamous Cell Carcinoma
Ann Surg Oncol
2021
28(13):8508-8518
PubMed ID: 34185205
DOI: 10.1245/s10434-021-10089-9
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12107
Matsubara D, Konishi H, Arita T, Shoda K, Fujita Y, Ogino S, Takao K, Nanishi K, Kosuga T, Komatsu S, Shiozaki A, Fujiwara H, Okamoto K, Otsuji E.
Involvement of Intracellular and Extracellular High-Mobility Group Box-1 in the Progression of Esophageal Squamous Cell Carcinoma.
Ann. Surg. Oncol.
2020
PubMed ID: 32221734
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13092
Feng Y, Yan S, Huang Y, Huang Q, Wang F, Lei Y.
High expression of RABL6 promotes cell proliferation and predicts poor prognosis in esophageal squamous cell carcinoma.
BMC Cancer
2020
PubMed ID: 32600359
DOI: 10.1186/s12885-020-07068-w
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13600
Sano H, Futamura M, Gaowa S, Kamino H, Nakamura Y, Yamaguchi K, Tanaka Y, Yasufuku I, Nakakami A, Arakawa H, Yoshida K.
p53/Mieap-regulated mitochondrial quality control plays an important role as a tumor suppressor in gastric and esophageal cancers
Biochem Biophys Res Commun
2020
529(3):582-589.
PubMed ID: 32736677
DOI: 10.1016/j.bbrc.2020.05.168
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11631
Konishi T, Shiozaki A, Kosuga T, Kudou M, Shoda K, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, Marunaka Y, Otsuji E.
LRRC8A Expression Influences Growth of Esophageal Squamous Cell Carcinoma.
Am. J. Pathol.
2019
PubMed ID: 31323188
DOI: 10.1016/j.ajpath.2019.06.006
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10798
Shinno N, Kimura H, Sada R, Takiguchi S, Mori M, Fumoto K, Doki Y, Kikuchi A.
Activation of the Dickkopf1-CKAP4 pathway is associated with poor prognosis of esophageal cancer and anti-CKAP4 antibody may be a new therapeutic drug.
Oncogene
2018
37(26):3471-3484
PubMed ID: 29563607
DOI: 10.1038/s41388-018-0179-2
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11092
Shin WS, Gim J, Won S, Lee ST.
Biphasic regulation of tumorigenesis by PTK7 expression level in esophageal squamous cell carcinoma.
Sci Rep
2018
8(1):8519
PubMed ID: 29867084
DOI: 10.1038/s41598-018-26957-6
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4355
Furukawa H, Makino T, Yamasaki M, Tanaka K, Miyazaki Y, Takahashi T, Kurokawa Y, Nakajima K, Takiguchi S, Mori M, Doki Y.
PRIMA-1 induces p53-mediated apoptosis by upregulating Noxa in esophageal squamous cell carcinoma with TP53 missense mutation.
Cancer Sci.
2018
109(2):412-421
PubMed ID: 29168598
DOI: 10.1111/cas.13454
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4356
Ishibashi O, Akagi I, Ogawa Y, Inui T.
MiR-141-3p is upregulated in esophageal squamous cell carcinoma and targets pleckstrin homology domain leucine-rich repeat protein phosphatase-2, a negative regulator of the PI3K/AKT pathway.
Biochem Biophys Res Commun.
2018
501(2):507-513
PubMed ID: 29738771
DOI: 10.1016/j.bbrc.2018.05.025
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9448
Chihiro Kajiwara, Katsumi Fumoto, Hirokazu Kimura, Satoshi Nojima, Keita Asano, Kazuki Odagiri, Makoto Yamasaki, Hayato Hikita, Tetsuo Takehara, Yuichiro Doki, Eiichi Morii, Akira Kikuchii
p63-Dependent Dickkopf3 Expression Promotes Esophageal Cancer Cell Proliferation via CKAP4
Cancer Res
2018
78(21):6107-6120
PubMed ID: 30181180
DOI: 10.1158/0008-5472.CAN-18-1749
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13126
Gaowa S, Futamura M, Tsuneki M, Kamino H, Tajima JY, Mori R, Arakawa H, Yoshida K.
Possible role of p53/Mieap-regulated mitochondrial quality control as a tumor suppressor in human breast cancer.
Cancer Sci
2018
PubMed ID: 30290054
DOI: 10.1111/cas.13824
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14899
Shiozaki A, Hikami S, Ichikawa D, Kosuga T, Shimizu H, Kudou M, Yamazato Y, Kobayashi T, Shoda K, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, Marunaka Y, Otsuji E.
Anion exchanger 2 suppresses cellular movement and has prognostic significance in esophageal squamous cell carcinoma
Oncotarget
2018
9(40):25993-26006
PubMed ID: 29899837
DOI: 10.18632/oncotarget.25417
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10116
Akagi I, Ishibashi O.
RNA-Seq analysis of human cell lines established from normal and neoplastic esophageal squamous epithelium.
Genom Data
2017
12:4-6
PubMed ID: 28224081
DOI: 10.1016/j.gdata.2017.02.002
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10141
Sugase T, Takahashi T, Serada S, Nakatsuka R, Fujimoto M, Ohkawara T, Hara H, Nishigaki T, Tanaka K, Miyazaki Y, Makino T, Kurokawa Y, Yamasaki M, Nakajima K, Takiguchi S, Kishimoto T, Mori M, Doki Y, Naka T.
Suppressor of cytokine signaling-1 gene therapy induces potent antitumor effect in patient-derived esophageal squamous cell carcinoma xenograft mice.
Int. J. Cancer
2017
140:2608-2621
PubMed ID: 28233302
DOI: 10.1002/ijc.30666
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10323
Liu K, Song G, Zhang X, Li Q, Zhao Y, Zhou Y, Xiong R, Hu X, Tang Z, Feng G.
PTK7 is a novel oncogenic target for esophageal squamous cell carcinoma.
World J Surg Oncol
2017
15:105
PubMed ID: 28545451
DOI: 10.1186/s12957-017-1172-x
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10353
Kawaguchi T, Komatsu S, Ichikawa D, Hirajima S, Nishimura Y, Konishi H, Shiozaki A, Fujiwara H, Okamoto K, Tsuda H, Otsuji E.
Overexpression of TRIM44 is related to invasive potential and malignant outcomes in esophageal squamous cell carcinoma.
Tumour Biol.
2017
39:1010428317700409
PubMed ID: 28618928
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10365
Yamamoto M, Yamasaki M, Tsukao Y, Tanaka K, Miyazaki Y, Makino T, Takahashi T, Kurokawa Y, Nakajima K, Takiguchi S, Mori M, Doki Y.
Poly (ADP-ribose) polymerase-1 inhibition decreases proliferation through G2/M arrest in esophageal squamous cell carcinoma.
Oncol Lett
2017
14:1581-1587
PubMed ID: 28789382
DOI: 10.3892/ol.2017.6334
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10449
Yoshioka M, Ohashi S, Ida T, Nakai Y, Kikuchi O, Amanuma Y, Matsubara J, Yamada A, Miyamoto S, Natsuizaka M, Nakagawa H, Chiba T, Seno H, Muto M.
Distinct effects of EGFR inhibitors on epithelial- and mesenchymal-like esophageal squamous cell carcinoma cells.
J. Exp. Clin. Cancer Res.
2017
36:101
PubMed ID: 28764725
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14228
Fujita Y, Masuda K, Hamada J, Shoda K, Naruto T, Hamada S, Miyakami Y, Kohmoto T, Watanabe M, Takahashi R, Tange S, Saito M, Kudo Y, Fujiwara H, Ichikawa D, Tangoku A, Otsuji E, Imoto I.
KH-type splicing regulatory protein is involved in esophageal squamous cell carcinoma progression
Oncotarget
2017
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PubMed ID: 29254151
DOI: 10.18632/oncotarget.20926
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14243
Shiozaki A, Kudou M, Ichikawa D, Shimizu H, Arita T, Kosuga T, Konishi H, Komatsu S, Fujiwara H, Okamoto K, Kishimoto M, Marunaka Y, Otsuji E.
Expression and role of anion exchanger 1 in esophageal squamous cell carcinoma
Oncotarget
2017
8(11):17921-17935
PubMed ID: 28160546
DOI: 10.18632/oncotarget.14900
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9599
Kikuchi O, Ohashi S, Horibe T, Kohno M, Nakai Y, Miyamoto S, Chiba T, Muto M, Kawakami K.
Novel EGFR-targeted strategy with hybrid peptide against oesophageal squamous cell carcinoma.
Sci Rep
2016
6:22452
PubMed ID: 26956916
DOI: 10.1038/srep22452
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9724
Hara H, Takahashi T, Serada S, Fujimoto M, Ohkawara T, Nakatsuka R, Harada E, Nishigaki T, Takahashi Y, Nojima S, Miyazaki Y, Makino T, Kurokawa Y, Yamasaki M, Miyata H, Nakajima K, Takiguchi S, Morii E, Mori M, Doki Y, Naka T.
Overexpression of glypican-1 implicates poor prognosis and their chemoresistance in oesophageal squamous cell carcinoma.
Br. J. Cancer
2016
115:66-75
PubMed ID: 27310703
DOI: 10.1038/bjc.2016.183
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9433
Yunyan Wu, Qiang Liu, Xu Yan, Yukio Kato, Makiko Tanaka, Sadaki Inokuchi, Tadashi Yoshizawa, Satoko Morohashi, Hiroshi Kijima
Podoplanin-mediated TGF-β-induced Epithelial-Mesenchymal Transition and Its Correlation With bHLH Transcription Factor DEC in TE-11 Cells
Int J Oncol
2016
48(6):2310-20
PubMed ID: 27035755
DOI: 10.3892/ijo.2016.3445
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12663
Song IH, Lee TS, Park YS, Lee JS, Lee BC, Moon BS, An GI, Lee HW, Kim KI, Lee YJ, Kang JH, Lim SM.
Immuno-PET Imaging and Radioimmunotherapy of 64Cu-/177Lu-Labeled Anti-EGFR Antibody in Esophageal Squamous Cell Carcinoma Model
J Nucl Med
2016
57(7):1105-11
PubMed ID: 26917708
DOI: 10.2967/jnumed.115.167155
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12664
Shin WS, Hong Y, Lee HW, Lee ST.
Catalytically defective receptor protein tyrosine kinase PTK7 enhances invasive phenotype by inducing MMP-9 through activation of AP-1 and NF-κB in esophageal squamous cell carcinoma cells
Oncotarget
2016
7(45):73242-73256
PubMed ID: 27689325
DOI: 10.18632/oncotarget.12303
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12969
Hamada J, Shoda K, Masuda K, Fujita Y, Naruto T, Kohmoto T, Miyakami Y, Watanabe M, Kudo Y, Fujiwara H, Ichikawa D, Otsuji E, Imoto I.
Tumor-promoting function and prognostic significance of the RNA-binding protein T-cell intracellular antigen-1 in esophageal squamous cell carcinoma
Oncotarget
2016
7(13):17111-28
PubMed ID: 26958940
DOI: 10.18632/oncotarget.7937
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14119
Park M, Yoon HJ, Kang MC, Kwon J, Lee HW.
PTK7 regulates radioresistance through nuclear factor-kappa B in esophageal squamous cell carcinoma
Tumour Biol
2016
37(10):14217-14224
PubMed ID: 27557627
DOI: 10.1007/s13277-016-5288-3
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Kikuchi O, Ohashi S, Nakai Y, Nakagawa S, Matsuoka K, Kobunai T, Takechi T, Amanuma Y, Yoshioka M, Ida T, Yamamoto Y, Okuno Y, Miyamoto S, Nakagawa H, Matsubara K, Chiba T, Muto M.
Novel 5-fluorouracil-resistant human esophageal squamous cell carcinoma cells with dihydropyrimidine dehydrogenase overexpression.
Am J Cancer Res
2015
5:2431-40
PubMed ID: 26396918
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7382
Saito S, Morishima K, Ui T, Hoshino H, Matsubara D, Ishikawa S, Aburatani H, Fukayama M, Hosoya Y, Sata N, Lefor AK, Yasuda Y, Niki T.
The role of HGF/MET and FGF/FGFR in fibroblast-derived growth stimulation and lapatinib-resistance of esophageal squamous cell carcinoma.
BMC Cancer
2015
15:82
PubMed ID: 25884729
DOI: 10.1186/s12885-015-1065-8
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7493
Wakita A, Motoyama S, Sato Y, Koyota S, Usami S, Yoshino K, Sasaki T, Imai K, Saito H, Minamiya Y.
REG Iα activates c-Jun through MAPK pathways to enhance the radiosensitivity of squamous esophageal cancer cells.
Tumour Biol.
2015
36:5249-54
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15159
Honda S, Loher P, Shigematsu M, Palazzo JP, Suzuki R, Imoto I, Rigoutsos I, Kirino Y.
Sex hormone-dependent tRNA halves enhance cell proliferation in breast and prostate cancers
Proc Natl Acad Sci U S A
2015
112(29):E3816-25
PubMed ID: 26124144
DOI: 10.1073/pnas.1510077112
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19049
Kwon J, Yoon HJ, Kim JH, Lee TS, Song IH, Lee HW, Kang MC, Park JH.
Cetuximab inhibits cisplatin-induced activation of EGFR signaling in esophageal squamous cell carcinoma
Oncol Rep
2014
32(3):1188-92
PubMed ID: 24993015
DOI: 10.3892/or.2014.3302
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15822
Ohashi S, Kikuchi O, Tsurumaki M, Nakai Y, Kasai H, Horimatsu T, Miyamoto S, Shimizu A, Chiba T, Muto M.
Preclinical validation of talaporfin sodium-mediated photodynamic therapy for esophageal squamous cell carcinoma
PLoS One
2014
9(8):e103126
PubMed ID: 25090101
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Inhibition of mitogen-activated protein kinase pathway can induce upregulation of human leukocyte antigen class I without PD-L1-upregulation in contrast to interferon-γ treatment
Inhibition of mitogen-activated protein kinase pathway can induce upregulation of human leukocyte antigen class I without PD-L1-upregulation in contrast to interferon-γ treatment
Cancer Sci
2014
105(10):1236-44
PubMed ID: 25154680
DOI: 10.1111/cas.12503
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Zhang S, Tang W, Weng S, Liu X, Rao B, Gu J, Chen S, Wang Q, Shen X, Xue R, Dong L.
Apollon modulates chemosensitivity in human esophageal squamous cell carcinoma
Oncotarget
2014
5(16):7183-97
PubMed ID: 25216531
DOI: 10.18632/oncotarget.2293
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Yoshino K, Motoyama S, Koyota S, Shibuya K, Sato Y, Sasaki T, Wakita A, Saito H, Minamiya Y, Sugiyama T, Ogawa J.
Identification of insulin-like growth factor 2 mRNA-binding protein 3 as a radioresistance factor in squamous esophageal cancer cells
Dis Esophagus
2014
27(5):479-84
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Ichiro Akagi, Osamu Ishibashi, Takeshi Matsutani, Nobutoshi Hagiwara, Akihisa Matsuda, Tsutomu Nomura, Hiroshi Makino, Hiroshi Yoshida, Masao Miyashita, Eiji Uchida
Comprehensive Analysis of MicroRNA and mRNA Expression in Normal and Tumorous Human Esophageal Squamous Cell Lines Using Microarray Datasets
Dataset Papers in Science
2014
1-3:2014-12-15
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Yeo SY, Ha SY, Yu EJ, Lee KW, Kim JH, Kim SH.
ZNF282 (Zinc finger protein 282), a novel E2F1 co-activator, pr
Oncotarget
2014
5(23):12260-72
PubMed ID: 25373738
DOI: 10.18632/oncotarget.2630
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18742
Sugimura K, Miyata H, Tanaka K, Hamano R, Takahashi T, Kurokawa Y, Yamasaki M, Nakajima K, Takiguchi S, Mori M, Doki Y.
Let-7 expression is a significant determinant of response to chemotherapy through the regulation of IL-6/STAT3 pathway in esophageal squamous cell carcinoma
Clin Cancer Res
2012
18(18):5144-53
PubMed ID: 22847808
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Matsushima K, Isomoto H, Yamaguchi N, Inoue N, Machida H, Nakayama T, Hayashi T, Kunizaki M, Hidaka S, Nagayasu T, Nakashima M, Ujifuku K, Mitsutake N, Ohtsuru A, Yamashita S, Korpal M, Kang Y, Gregory PA, Goodall GJ, Kohno S, Nakao K.
MiRNA-205 modulates cellular invasion and migration via regulating zinc finger E-box binding homeobox 2 expression in esophageal squamous cell carcinoma cells
J Transl Med
2011
9:30
PubMed ID: 21426561
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Usami S, Motoyama S, Koyota S, Wang J, Hayashi-Shibuya K, Maruyama K, Takahashi N, Saito H, Minamiya Y, Takasawa S, Ogawa J, Sugiyama T.
Regenerating gene I regulates interleukin-6 production in squamous esophageal cancer cells.
Biochem. Biophys. Res. Commun.
2010
392:4-8
PubMed ID: 20056108
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Ooki A, Yamashita K, Kikuchi S, Sakuramoto S, Katada N, Watanabe M.
Phosphatase of regenerating liver-3 as a convergent therapeutic target for lymph node metastasis in esophageal squamous cell carcinoma.
Int. J. Cancer
2010
127:543-54
PubMed ID: 19960436
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Rahadiani N, Ikeda J, Makino T, Tian T, Qiu Y, Mamat S, Wang Y, Doki Y, Aozasa K, Morii E.
Tumorigenic role of podoplanin in esophageal squamous-cell carcinoma
Ann Surg Oncol
2010
17(5):1311-23
PubMed ID: 20066519
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Inoue N, Isomoto H, Matsushima K, Hayashi T, Kunizaki M, Hidaka S, Machida H, Mitsutake N, Nanashima A, Takeshima F, Nakayama T, Ohtsuru A, Nakashima M, Nagayasu T, Yamashita S, Nakao K, Kohno S.
Down-regulation of microRNA 10a expression in esophageal squamous cell carcinoma cells
Oncol Lett
2010
1(3):527-531
PubMed ID: 22966337
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