細胞番号 : 細胞名
RCB1947 : Ca Ski
update : 2023/06/30
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| 細胞特性(Comment:英) | Human cell line derived from uterine cervical epidermoid carcinoma. TKG0366 (Deposited from Tohoku Univ.). |
| 細胞特性(日) | ヒト子宮頸癌由来細胞株。Epidermoid carcinoma。 TKG0366 (東北大学医用細胞資源センターからの寄託)。 |
| 細胞特性(寄託者記述:英) | |
| 細胞特性(寄託者記述:日) | |
| 使用条件(英) | There is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC. |
| 使用条件(日) | 基礎的研究につきましては、使用制限はありません。商業利用や特許取得を目的とする場合は、事前に必ず理研細胞バンクに連絡をすること。 |
| 備考(英) | |
| 備考(日) | |
| 提供申込書類(英) |
Order Form(C-0005.pdf)
MTA(C-0007.pdf)
MTA(C-0007p.pdf)
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Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
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| 提供申込書類(日) |
依頼書C-0001.pdf
同意書(非営利学術目的)C-0003.pdf
同意書(営利目的)C-0003p.pdf
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提供同意書は、使用機関の種類や目的に応じて、非営利学術目的 (C-XXXX) と営利目的 (C-XXXXp) の2種類があります。該当する提供同意書をご使用ください（詳細）。特許等の取得及び商業利用等は事前に必ず cellbank.brc@riken.jp までご連絡ください。
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| 提供手数料 |
手数料とお支払いについてはこちらをご覧ください。 |
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細胞基本情報
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寄託者 |
Obinata, Masuo
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| 樹立者 |
Pattillo, R. A.
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| 寄託日 |
2004
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| 元の細胞 |
TKG0366
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| 動物種 |
_human
< Mammals
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| 属名 |
Homo
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| 種名 |
sapiens
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| 性別 |
Female
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| 齢 |
40 years
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| 採取組織 |
cervix
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| 病名 |
epidermoid carcinoma
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| 細胞分類 |
cancer
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| 入手歴 |
Cell Resource Center for Biomedical Research, Tohoku University（TKG0366）
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|
細胞寿命 |
infinite
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| 細胞形態 |
epithelial-like
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| Cellosaurus(Expasy) |
CVCL_1100
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細胞培養・検査情報
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寄託時情報 |
ロット情報 |
| 培地・試薬情報 |
培地・試薬一覧はこちらをご覧ください。 |
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培養形態 |
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Adherent cells
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| 培地 |
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RPMI1640 + 10% FBS
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| 抗生物質 |
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Free
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|
継代方法 |
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0.25% Trypsin
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|
継代密度 |
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1 : 8 split
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| 継代・培地交換頻度 |
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Subculture : 2 times/week
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| 培養最適温度 |
|
37
℃
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| 二酸化炭素濃度 |
|
5
%
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| 凍結培地 |
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Medium + 10% DMSO
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| 凍結方法 |
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Slow freezing
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| マイコプラズマ |
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(-)
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| アイソザイム検査 |
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LD, NP
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| 個体識別検査 |
|
OK
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| 画像情報 |
寄託時情報 | ロット情報 |
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| 文献情報 |
Reference(英) |
9件
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| Reference(日) |
0件
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| 利用者成果(英) |
12件
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| 利用者成果(日) |
0件
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| Reference(英) |
|
3250
Kurban G, Ishiwata T, Lu, Y P, Fujii T, Kawahara K, Naito Z, Yamada N, Asano G
[Expression and intracytoplasmic signal transduction pathway of fibroblast growth factor (FGF)-10 in human cervical cancer cell lines]
J Nippon Med Sch
2001
68:253-8
PubMed ID: 11404772
DOI: 10.1272/jnms.68.253
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3256
Hendricks, D T, Taylor R, Reed M, Birrer, M J
FHIT gene expression in human ovarian, endometrial, and cervical cancer cell lines.
Cancer Res
1997
57:2112-5
PubMed ID: 9187105
|
|
3249
Baker, C C, Phelps, W C, Lindgren V, Braun, M J, Gonda, M A, Howley, P M
Structural and transcriptional analysis of human papillomavirus type 16 sequences in cervical carcinoma cell lines.
J Virol
1987
61:962-71
PubMed ID: 3029430
DOI: 10.1128/JVI.61.4.962-971.1987
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5053
Hussa RO, Pattillo RA, Ruckert AC, Rinke ML, Cortesi JP, Fein HG.
Optimization of the production of hCG beta-like material by CaSki human cervical carcinoma cells in roller bottle culture.
Oncology
1986
43(1):54-9
PubMed ID: 3753621
DOI: 10.1159/000226105
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5054
Hussa RO, Fein HG, Pattillo RA, Nagelberg SB, Rosen SW, Weintraub BD, Perini F, Ruddon RW, Cole LA.
A distinctive form of human chorionic gonadotropin beta-subunit-like material produced by cervical carcinoma cells.
Cancer Res
1986
46(4 Pt 2):1948-54
PubMed ID: 2418956
|
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5055
Hussa RO, Maruo T, Strobel JL, Pattillo RA, Mochizuki M.
Production of tumor-associated antigen, TA-4, by the CaSki cervical carcinoma cell line.
Obstet Gynecol
1986
67(6):802-5
PubMed ID: 2422615
DOI: 10.1097/00006250-198606000-00010
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3255
Yee C, Krishnan-Hewlett I, Baker, C C, Schlegel R, Howley, P M
Presence and expression of human papillomavirus sequences in human cervical carcinoma cell lines.
Am J Pathol
1985
119:361-6
PubMed ID: 2990217
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3254
Pater, M M, Pater A
Human papillomavirus types 16 and 18 sequences in carcinoma cell lines of the cervix.
Virology
1985
145:313-8
PubMed ID: 2992153
DOI: 10.1016/0042-6822(85)90164-3
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3253
Pattillo, R A, Hussa, R O, Story, M T, Ruckert, A C, Shalaby, M R, Mattingly, R F
Tumor antigen and human chorionic gonadotropin in CaSki cells: a new epidermoid cervical cancer cell line.
Science
1977
196:1456-8
PubMed ID: 867042
DOI: 10.1126/science.867042
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| 利用者成果(英) |
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19540
Furukawa Y, Ishii M, Ando J, Ikeda K, Igarashi KJ, Kinoshita S, Azusawa Y, Toyota T, Honda T, Nakanishi M, Ohshima K, Masuda A, Yoshida E, Kitade M, Porteus M, Terao Y, Nakauchi H, Ando M.
iPSC-derived hypoimmunogenic tissue resident memory T cells mediate robust anti-tumor activity against cervical cancer
Cell Rep Med
2023
4(12):101327
PubMed ID: 38091985
DOI: 10.1016/j.xcrm.2023.101327
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18210
Krishnamurthy S, Yoda H, Hiraoka K, Inoue T, Lin J, Shinozaki Y, Watanabe T, Koshikawa N, Takatori A, Nagase H.
Targeting the mutant PIK3CA gene by DNA-alkylating pyrrole-imidazole polyamide in cervical cancer
Cancer Sci
2021
112(3):1141-1149
PubMed ID: 33377228
DOI: 10.1111/cas.14785
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13328
Kagabu M, Yoshino N, Saito T, Miura Y, Takeshita R, Murakami K, Kawamura H, Baba T, Sugiyama T.
The efficacy of a third-generation oncolytic herpes simplex viral therapy for an HPV-related uterine cervical cancer model.
Int J Clin Oncol
2021
26(3):591-597.
PubMed ID: 33146805
DOI: 10.1007/s10147-020-01823-6
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20249
Makise M, Uchimura R, Higashi K, Mashiki Y, Shiraishi R, Shutoku Y, Kuniyasu A.
Overexpression of the nucleoporin Nup88 stimulates migration and invasion of HeLa cells.
Histochem Cell Biol
2021
PubMed ID: 34331103
DOI: 10.1007/s00418-021-02020-w
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20389
D S P, Chaturvedi PK, Shimokawa T, Kim KH, Park WY.
Silencing of Fused Toes Homolog (FTS) Increases Radiosensitivity to Carbon-Ion Through Downregulation of Notch Signaling in Cervical Cancer Cells.
Front Oncol
2021
11:730607
PubMed ID: 34765546
DOI: 10.3389/fonc.2021.730607
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4371
Isono T, Chano T, Yoshida T, Kageyama S, Kawauchi A, Yonese J, Yuasa T.
Abundance of TRAIL attenuated by HIF2α and c-FLIP affects malignancy in renal cell carcinomas.
Oncotarget
2018
9(33):23091-23101
PubMed ID: 29796174
DOI: 10.18632/oncotarget.25214
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14611
Ueda T, Tsubamoto H, Inoue K, Sakata K, Shibahara H, Sonoda T.
Itraconazole Modulates Hedgehog, WNT/β-catenin, as well as Akt Signalling, and Inhibits Proliferation of Cervical Cancer Cells
Anticancer Res
2017
3521-3526
PubMed ID: 28668841
DOI: 10.21873/anticanres.11720
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5011
Nagura M, Matsumura N, Baba T, Murakami R, Kharma B, Hamanishi J, Yamaguchi K, Abiko K, Koshiyama M, Mandai M, Murata T, Murphy SK, Konishi I.
Invasion of uterine cervical squamous cell carcinoma cells is facilitated by locoregional interaction with cancer-associated fibroblasts via activating transforming growth factor-beta.
Gynecol Oncol
2015
136(1):104-11
PubMed ID: 25434636
DOI: 10.1016/j.ygyno.2014.11.075
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6096
Sakamoto K, Fujii T, Kawachi H, Miki Y, Omura K, Morita K, Kayamori K, Katsube K, Yamaguchi A.
Reduction of NOTCH1 expression pertains to maturation abnormalities of keratinocytes in squamous neoplasms.
Lab Invest
2012
92(5):688-702
PubMed ID: 22330335
DOI: 10.1038/labinvest.2012.9
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7659
Murata T, Mizushima H, Chinen I, Moribe H, Yagi S, Hoffman RM, Kimura T, Yoshino K, Ueda Y, Enomoto T, Mekada E.
HB-EGF and PDGF mediate reciprocal interactions of carcinoma cells with cancer-associated fibroblasts to support progression of uterine cervical cancers.
Cancer Res.
2011
71:6633-42
PubMed ID: 22009535
DOI: 10.1158/0008-5472.CAN-11-0034
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8093
Matsuda Y, Fujii T, Suzuki T, Yamahatsu K, Kawahara K, Teduka K, Kawamoto Y, Yamamoto T, Ishiwata T, Naito Z.
Comparison of fixation methods for preservation of morphology, RNAs, and proteins from paraffin-embedded human cancer cell-implanted mouse models.
J. Histochem. Cytochem.
2011
59:68-75
PubMed ID: 20940453
DOI: 10.1369/jhc.2010.957217
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3516
Takaoka N, Takayama T, Teratani T, Sugiyama T, Mugiya S, Ozono S.
Analysis of the regulation of fatty acid binding protein 7 expression in human renal carcinoma cell lines.
BMC Mol Biol
2011
12:31
PubMed ID: 21771320
DOI: 10.1186/1471-2199-12-31
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