User's Publication |
19774
Kasamatsu A, Nozaki R, Kawasaki K, Saito T, Minemura C, Seki N, Moss J, Uzawa K.
Synthetic Circular RNA for microRNA-1269a Suppresses Tumor Progression in Oral Squamous Cell Carcinoma
Cancers (Basel)
2024
16(6):1242
PubMed ID: 38539573
DOI: 10.3390/cancers16061242
|
21577
Al Awadh AA, Sakagami H, Amano S, Sayed AM, Abouelela ME, Alhasaniah AH, Aldabaan N, Refaey MS, Abdelhamid RA, Khalil HMA, Hamdan DI, Abdel-Sattar ES, Orabi MAA.
In vitro cytotoxicity of Withania somnifera (L.) roots and fruits on oral squamous cell carcinoma cell lines: a study supported by flow cytometry, spectral, and computational investigations.
Front Pharmacol
2024
15:1325272
PubMed ID: 38303989
DOI: 10.3389/fphar.2024.1325272
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21708
Inomata M, Abe M, Kawase Y, Hayashi T, Amano S, Sakagami H.
Dectin-1/SYK Activation Induces Antimicrobial Peptide and Negative Regulator of NF-κB Signaling in Human Oral Epithelial Cells.
In Vivo
2024
38(3):1042-1048
PubMed ID: 38688646
DOI: 10.21873/invivo.13537
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21752
Yonesi A, Tomihara K, Takatsuka D, Tachinami H, Yamazaki M, Jadidi ARY, Takaichi M, Imaue S, Fujiwara K, Yamada SI, Tanuma JI, Noguchi M.
Rapamycin Induces Phenotypic Alterations in Oral Cancer Cells That May Facilitate Antitumor T Cell Responses.
Biomedicines
2024
12(5)
PubMed ID: 38791040
DOI: 10.3390/biomedicines12051078
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21807
Takatsuka D, Tachinami H, Suzuki N, Yamazaki M, Yonesi A, Takaichi M, Imaue S, Yamada SI, Tanuma JI, Noguchi M, Tomihara K.
PAK4 inhibition augments anti-tumour effect by immunomodulation in oral squamous cell carcinoma.
Sci Rep
2024
14(1):14092
PubMed ID: 38890401
DOI: 10.1038/s41598-024-64126-0
|
21900
Mayuka Yamagata, Sen Higashi, Noboru Yaida, Akane Ichihara, Manabu Habu, Masaaki Sasaguri, Kazuhiro Tominaga, Hiroshi Takeuchi
Enhanced degradation of epidermal growth factor receptor by metformin
Oral Science International
2024
21:59-67
DOI: 10.1002/osi2.1179
|
22052
Abé T, Yamazaki M, Nozumi M, Maruyama S, Takamura K, Ohashi R, Ajioka Y, Tanuma JI.
Ladinin-1 in actin arcs of oral squamous cell carcinoma is involved in cell migration and epithelial phenotype.
Sci Rep
2024
14(1):22778
PubMed ID: 39354061
DOI: 10.1038/s41598-024-74041-z
|
19591
Kawasaki Y, Omori Y, Suzuki S, Yamada T.
CD98hc as a marker of radiotherapy-resistant cancer stem cells in head and neck squamous cell carcinoma
Arch Med Sci
2023
19(6):1859-1868
PubMed ID: 38058706
DOI: 10.5114/aoms.2020.92872
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19748
Yamaki H, Kono M, Wakisaka R, Komatsuda H, Kumai T, Hayashi R, Sato R, Nagato T, Ohkuri T, Kosaka A, Ohara K, Kishibe K, Takahara M, Hayashi T, Kobayashi H, Katada A.
Brachyury-targeted immunotherapy combined with gemcitabine against head and neck cancer
Cancer Immunol Immunother
2023
72(8):2799-2812
PubMed ID: 37173455
DOI: 10.1007/s00262-023-03460-0
|
19759
Takanori Takenawa, Koji Harada, Tarannum Ferdous, Keisuke Kawasaki, Yasuhiro Kuramitsu, Katsuaki Mishima
Silencing of Tropomyosin 1 suppresses the proliferation, invasion and metastasis of oral squamous cell carcinoma in vitro
Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology
2023
35:282-287
DOI: 10.1016/j.ajoms.2022.10.004
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19822
Nakashiro KI, Tokuzen N, Saika M, Shirai H, Kuribayashi N, Goda H, Uchida D.
MicroRNA-1289 Functions as a Novel Tumor Suppressor in Oral Squamous Cell Carcinoma
Cancers (Basel)
2023
15(16):4138
PubMed ID: 37627167
DOI: 10.3390/cancers15164138
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19875
Abe T, Sakagami H, Amano S, Uota S, Bandow K, Uesawa Y, U S, Shibata H, Takemura Y, Kimura Y, Takao K, Sugita Y, Sato A, Tanuma SI, Takeshima H.
A Comparative Study of Tumor-Specificity and Neurotoxicity between 3-Styrylchromones and Anti-Cancer Drugs
Medicines (Basel)
2023
10(7):43
PubMed ID: 37505064
DOI: 10.3390/medicines10070043
|
21184
Chan NN, Yamazaki M, Maruyama S, Abé T, Haga K, Kawaharada M, Izumi K, Kobayashi T, Tanuma JI.
Cholesterol Is a Regulator of CAV1 Localization and Cell Migration in Oral Squamous Cell Carcinoma.
Int J Mol Sci
2023
24(7)
PubMed ID: 37047005
DOI: 10.3390/ijms24076035
|
21370
Yamada T, Yamamori Y, Matsuda N, Nagamune H, Ohkura K, Tomoyasu T, Tabata A.
Streptolysin S induces pronounced calcium-ion influx-dependent expression of immediate early genes encoding transcription factors.
Sci Rep
2023
13(1):13720
PubMed ID: 37608082
DOI: 10.1038/s41598-023-40981-1
|
21380
Tagawa Y, Sakagami H, Tanuma SI, Amano S, Uota S, Bandow K, Tomomura M, Uesawa Y, Takao K, Sugita Y, Yamamoto N, Sakashita H, Nakakaji R, Koizumi T, Mitsudo K, Tohnai I.
Potentiation of Anticancer Activity of G2/M Blockers by Mild Hyperthermia.
Anticancer Res
2023
43(8):3429-3439
PubMed ID: 37500171
DOI: 10.21873/anticanres.16518
|
21527
Orabi MAA, Orabi EA, Awadh AAA, Alshahrani MM, Abdel-Wahab BA, Sakagami H, Hatano T.
New Megastigmane and Polyphenolic Components of Henna Leaves and Their Tumor-Specific Cytotoxicity on Human Oral Squamous Carcinoma Cell Lines.
Antioxidants (Basel)
2023
12(11)
PubMed ID: 38001804
DOI: 10.3390/antiox12111951
|
20382
Fan M, Arai M, Tawada A, Chiba T, Fukushima R, Uzawa K, Shiiba M, Kato N, Tanzawa H, Takiguchi Y.
Contrasting functions of the epithelial‑stromal interaction 1 gene, in human oral and lung squamous cell cancers.
Oncol Rep
2022
47(1)
PubMed ID: 34738627
DOI: 10.3892/or.2021.8216
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20513
Kono M, Komatsuda H, Yamaki H, Kumai T, Hayashi R, Wakisaka R, Nagato T, Ohkuri T, Kosaka A, Ohara K, Kishibe K, Takahara M, Katada A, Hayashi T, Kobayashi H, Harabuchi Y.
Immunomodulation via FGFR inhibition augments FGFR1 targeting T-cell based antitumor immunotherapy for head and neck squamous cell carcinoma.
Oncoimmunology
2022
11(1):2021619
PubMed ID: 35003900
DOI: 10.1080/2162402X.2021.2021619
|
20544
Matsuda R, Sakagami H, Amano S, Iijima Y, Sano M, Uesawa Y, Tamura N, Oishi Y, Takeshima H.
Inhibition of Neurotoxicity/Anticancer Activity of Bortezomib by Caffeic Acid and Chlorogenic Acid.
Anticancer Res
2022
42(2):781-790
PubMed ID: 35093876
DOI: 10.21873/anticanres.15536
|
20559
Komatsu M, Saito K, Miyamoto I, Koike K, Iyoda M, Nakashima D, Kasamatsu A, Shiiba M, Tanzawa H, Uzawa K.
Aberrant GIMAP2 expression affects oral squamous cell carcinoma progression by promoting cell cycle and inhibiting apoptosis.
Oncol Lett
2022
23(2):49
PubMed ID: 34992682
DOI: 10.3892/ol.2021.13167
|
16180
Katsuhiro Asaka, Akira Fukatsu, Chiaki Komine
The Effectiveness of a Portable Fluorescence Spectrophotometer for Early Detection of Oral Cancer
Open Journal of Stomatology
2022
12:30-31
DOI: 10.4236/ojst.2022.121003
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16203
Sasabe E, Tomomura A, Liu H, Sento S, Kitamura N, Yamamoto T.
Epidermal growth factor/epidermal growth factor receptor signaling blockage inhibits tumor cell-derived exosome uptake by oral squamous cell carcinoma through macropinocytosis
Cancer Sci
2022
113(2):609-621
PubMed ID: 34874595
DOI: 10.1111/cas.15225
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20638
Shahbaz K, Asif JA, Liszen T, Nurul AA, Alam MK.
Cytotoxic and Antioxidant Effects of Phoenix dactylifera L. (Ajwa Date Extract) on Oral Squamous Cell Carcinoma Cell Line.
Biomed Res Int
2022
2022:5792830
PubMed ID: 35233390
DOI: 10.1155/2022/5792830
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20648
Naitoh K, Orihara Y, Sakagami H, Miura T, Satoh K, Amano S, Bandow K, Iijima Y, Kurosaki K, Uesawa Y, Hashimoto M, Wakabayashi H.
Tumor-Specificity, Neurotoxicity, and Possible Involvement of the Nuclear Receptor Response Pathway of 4,6,8-Trimethyl Azulene Amide Derivatives.
Int J Mol Sci
2022
23(5)
PubMed ID: 35269748
DOI: 10.3390/ijms23052601
|
20658
Tabata A, Shirai R, Miki H, Nishikawa Y, Kashima T, Aoyama T, Murakami S, Azuma M, Tomoyasu T, Nagamune H.
Hapten-labeled fusion-polymerase chain reaction of multiple marker genes for the application of immunochromatographic test.
J Biosci Bioeng
2022
PubMed ID: 35450786
DOI: 10.1016/j.jbiosc.2022.03.006
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20815
Hossain M, Roayapalley PK, Sakagami H, Satoh K, Bandow K, Das U, Dimmock JR.
Dichloroacetyl Amides of 3,5-Bis(benzylidene)-4-piperidones Displaying Greater Toxicity to Neoplasms than to Non-Malignant Cells.
Medicines (Basel)
2022
9(6)
PubMed ID: 35736248
DOI: 10.3390/medicines9060035
|
20884
Shindo A, Kusano M, Sakagami H, Amano S, Inomata M, Abe M, Okazawa M, Ooka T.
Comparison of UVC Sensitivity and Dectin-2 Expression Between Malignant and Non-malignant Cells.
In Vivo
2022
36(5):2116-2125
PubMed ID: 36099100
DOI: 10.21873/invivo.12937
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20965
Morisaka H, Takaishi M, Akira S, Sano S.
Keratinocyte Regnase-1, a down-regulator of skin inflammation, contributes to protection against tumor promotion by limiting COX-2 expression.
J Invest Dermatol
2022
PubMed ID: 36470473
DOI: 10.1016/j.jid.2022.11.007
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13361
Luo F, Sugita H, Muraki K, Saeki S, Chaipech S, Pongpiriyadacha Y, Muraoka O, Morikawa T.
Anti-proliferative activities of coumarins from the Thai medicinal plant Mammea siamensis (Miq.) T. Anders. against human digestive tract carcinoma cell lines.
Fitoterapia
2021
PubMed ID: 33246033
DOI: 10.1016/j.fitote.2020.104780
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20020
Shishido K, Kuroishi T, Sugawara S.
P2 purinergic receptor signaling and interleukin-1 synergistically induce interleukin-6 production in a human oral squamous carcinoma cell line.
J Oral Biosci
2021
PubMed ID: 33497843
DOI: 10.1016/j.job.2021.01.004
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13580
Matsumoto A, Tabata A, Ohkura K, Oda H, Kodama C, Ohkuni H, Takao A, Kikuchi K, Tomoyasu T, Nagamune H.
Molecular characteristics of an adhesion molecule containing cholesterol-dependent cytolysin-motif produced by mitis group streptococci
Microbiol Immunol
2021
65(2):61-75
PubMed ID: 33331679
DOI: 10.1111/1348-0421.12868
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20085
Kase Y, Uzawa K, Wagai S, Yoshimura S, Yamamoto JI, Toeda Y, Okubo M, Eizuka K, Ando T, Nobuchi T, Kawasaki K, Saito T, Iyoda M, Nakashima D, Kasamatsu A, Tanzawa H.
Engineered exosomes delivering specific tumor-suppressive RNAi attenuate oral cancer progression.
Sci Rep
2021
11(1):5897
PubMed ID: 33723306
DOI: 10.1038/s41598-021-85242-1
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13776
Hamilton KL, Sheehan SA, Retzbach EP, Timmerman CA, Gianneschi GB, Tempera PJ, Balachandran P, Goldberg GS.
Effects of Maackia amurensis seed lectin (MASL) on oral squamous cell carcinoma (OSCC) gene expression and transcriptional signaling pathways
J Cancer Res Clin Oncol
2021
147(2):445-457
PubMed ID: 33205348
DOI: 10.1007/s00432-020-03456-8
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20350
Haga K, Yamazaki M, Maruyama S, Kawaharada M, Suzuki A, Hoshikawa E, Chan NN, Funayama A, Mikami T, Kobayashi T, Izumi K, Tanuma JI.
Crosstalk between oral squamous cell carcinoma cells and cancer-associated fibroblasts via the TGF-β/SOX9 axis in cancer progression.
Transl Oncol
2021
14(12):101236
PubMed ID: 34624685
DOI: 10.1016/j.tranon.2021.101236
|
15868
Itashiki Y, Harada K, Takenawa T, Ferdous T, Ueyama Y, Mishima K.
Antitumor effects of bevacizumab in combination with fluoropyrimidine drugs on human oral squamous cell carcinoma
Oncol Lett
2021
22(4):730
PubMed ID: 34429770
DOI: 10.3892/ol.2021.12991
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20455
Harada K, Ferdous T, Mishima K.
Efficacy of a Novel Oral Chemotherapeutic Agent, TAS-102, Against Human Oral Squamous Cell Carcinoma Cells.
Anticancer Res
2021
41(12):6039-6049
PubMed ID: 34848458
DOI: 10.21873/anticanres.15423
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16099
Saito K, Mitsui A, Sumardika IW, Yokoyama Y, Sakaguchi M, Kondo E.
PLOD2-driven IL-6/STAT3 signaling promotes the invasion and metastasis of oral squamous cell carcinoma via activation of integrin β1
Int J Oncol
2021
58(6):29
PubMed ID: 33887877
DOI: 10.3892/ijo.2021.5209
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16112
Akyu Takei R, Tomihara K, Yamazaki M, Moniruzzaman R, Heshiki W, Sekido K, Tachinami H, Sakurai K, Yonesi A, Imaue S, Fujiwara K, Noguchi M.
Protumor role of estrogen receptor expression in oral squamous cell carcinoma cells
Oral Surg Oral Med Oral Pathol Oral Radiol
2021
132(5):549-565
PubMed ID: 34518137
DOI: 10.1016/j.oooo.2021.04.006
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16136
Harada K, Ferdous T, Watanabe K, Mizukami Y, Mishima K.
Effects of an elemental diet, Elental®, may differ between healthy oral cells and oral cancer cells
Oncol Rep
2021
45(2):738-751
PubMed ID: 33416174
DOI: 10.3892/or.2020.7896
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16139
Kase-Kato I, Asai S, Minemura C, Tsuneizumi K, Oshima S, Koma A, Kasamatsu A, Hanazawa T, Uzawa K, Seki N.
Molecular Pathogenesis of the Coronin Family: CORO2A Facilitates Migration and Invasion Abilities in Oral Squamous Cell Carcinoma
Int J Mol Sci
2021
22(23):12684
PubMed ID: 34884487
DOI: 10.3390/ijms222312684
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16174
Roayapalley PK, Dimmock JR, Contreras L, Balderrama KS, Aguilera RJ, Sakagami H, Amano S, Sharma RK, Das U.
Design, Synthesis and Tumour-Selective Toxicity of Novel 1-[3-{3,5-Bis(benzylidene)-4-oxo-1-piperidino}-3-oxopropyl]-4-piperidone Oximes and Related Quaternary Ammonium Salts
Molecules
2021
26(23):7132
PubMed ID: 34885719
DOI: 10.3390/molecules26237132
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16195
Yamali C, Sakagami H, Uesawa Y, Kurosaki K, Satoh K, Masuda Y, Yokose S, Ece A, Bua S, Angeli A, Supuran CT, Gul HI.
Comprehensive study on potent and selective carbonic anhydrase inhibitors: Synthesis, bioactivities and molecular modelling studies of 4-(3-(2-arylidenehydrazine-1-carbonyl)-5-(thiophen-2-yl)-1H-pyrazole-1-yl) benzenesulfonamides
Eur J Med Chem
2021
217:113351
PubMed ID: 33744685
DOI: 10.1016/j.ejmech.2021.113351
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16196
Sakagami H, Furukawa T, Satoh K, Amano S, Iijima Y, Koshikawa T, Asai D, Fukuchi K, Takemura H, Kanamoto T, Yokose S.
Re-Evaluation of Chemotherapeutic Potential of Pyoktanin Blue
Medicines (Basel)
2021
8(7):33
PubMed ID: 34206186
DOI: 10.3390/medicines8070033
|
16200
Roayapalley PK, Sakagami H, Satoh K, Amano S, Bandow K, Aguilera RJ, Hernandez KGC, Schiaffino Bustamante AY, Dimmock SG, Sharma RK, Das U, Dimmock JR.
Cytotoxic Tumour-Selective 1,5-Diaryl-3-Oxo-1,4-Pentadienes Mounted on a Piperidine Ring
Medicines (Basel)
2021
8(12):78
PubMed ID: 34940290
DOI: 10.3390/medicines8120078
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16206
Koma A, Asai S, Minemura C, Oshima S, Kinoshita T, Kikkawa N, Koshizuka K, Moriya S, Kasamatsu A, Hanazawa T, Uzawa K, Seki N.
Impact of Oncogenic Targets by Tumor-Suppressive miR-139-5p and miR-139-3p Regulation in Head and Neck Squamous Cell Carcinoma
Int J Mol Sci
2021
22(18):9947
PubMed ID: 34576110
DOI: 10.3390/ijms22189947
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16862
Kawasaki M, Sakabe T, Kodani I, Umekita Y.
Cytoplasmic-only Expression of Maspin Predicts Poor Prognosis in Patients With Oral Squamous Cell Carcinoma
Anticancer Res
2021
41(9):4563-4570
PubMed ID: 34475084
DOI: 10.21873/anticanres.15269
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16975
Hotta H, Hamamura K, Shibuya H, Ohmi Y, Furukawa K, Furukawa K.
Lewis y Expressed in Oral Squamous Cell Carcinoma Attenuates Malignant Properties via Down-regulation of EGF Signaling
Anticancer Res
2021
41(4):1821-1830
PubMed ID: 33813387
DOI: 10.21873/anticanres.14948
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11844
Sakurai K, Tomihara K, Yamazaki M, Heshiki W, Moniruzzaman R, Sekido K, Tachinami H, Ikeda A, Imaue S, Fujiwara K, Noguchi M.
CD36 expression on oral squamous cell carcinoma cells correlates with enhanced proliferation and migratory activity.
Oral Dis
2020
26(4):745-755
PubMed ID: 31603606
DOI: 10.1111/odi.13210
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6954
Hayashi H, Chiba T, Mihara-Tomiyama N, Negishi T, Kodama Y, Sakashita H, Imai K.
Domain structures of mucosa-associated lymphoid tissue lymphoma translocation 1 protein for nuclear localization in oral carcinoma cells and the proliferation inhibition.
Biochem Biophys Res Commun
2020
522(3):799-804
PubMed ID: 31791579
DOI: 10.1016/j.bbrc.2019.11.171
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11965
Fujii S, Tajiri Y, Hasegawa K, Matsumoto S, Yoshimoto RU, Wada H, Kishida S, Kido MA, Yoshikawa H, Ozeki S, Kiyoshima T.
The TRPV4-AKT axis promotes oral squamous cell carcinoma cell proliferation via CaMKII activation.
Lab. Invest.
2020
PubMed ID: 31857698
DOI: 10.1038/s41374-019-0357-z
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12037
Nakagawa F, Higashi S, Ando E, Ohsumi T, Watanabe S, Takeuchi H.
Modification of TRPV4 activity by acetaminophen.
Heliyon
2020
PubMed ID: 32051870
DOI: 10.1016/j.heliyon.2020.e03301
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13013
Nakaya G, Sakagami H, Koga-Ogawa Y, Shiroto A, Nobesawa T, Ueda D, Nakatani S, Kobata K, Iijima Y, Tone S, David-Gonzalez A, Garcia-Contreras R, Tomomura M, Kito S, Tamura N, Takeshima H.
Augmentation of Neurotoxicity of Anticancer Drugs by X-Ray Irradiation.
In Vivo
2020
PubMed ID: 32354886
DOI: 10.21873/invivo.11869
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13093
Iijima Y, Bandow K, Amano S, Sano M, Hino S, Kaneko T, Horie N, Sakagami H.
Protection of Bortezomib-induced Neurotoxicity by Antioxidants.
Anticancer Res
2020
PubMed ID: 32620607
DOI: 10.21873/anticanres.14357
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13205
Teratani M, Nakamura S, Sakagami H, Fujise M, Hashimoto M, Okudaira N, Bandow K, Iijima Y, Nagai J, Uesawa Y, Wakabayashi H.
Antitumor Effects and Tumor-specificity of Guaiazulene-3-Carboxylate Derivatives Against Oral Squamous Cell Carcinoma In Vitro.
Anticancer Res
2020
PubMed ID: 32878776
DOI: 10.21873/anticanres.14491
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13427
Thahomina Khan, Kazunori Igarashi, Ami Tanabe, Taiki Miyazawa, Shigeto Fukushima, Yutaka Miura, Yu Matsumoto, Tatsuya Yamasoba, Akira Matsumoto, Horacio Cabral, and Kazunori Kataoka
Structural Control of Boronic Acid Ligands Enhances Intratumoral Targeting of Sialic Acid To Eradicate Cancer Stem-like Cells
ACS Appl. Bio Mater.
2020
PubMed ID: 35021680
DOI: 10.1021/acsabm.0c00530
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13775
Al-Tayar BA, Ahmad A, Yusoff ME, Abdullah SF, Mohamad NK, Md Hashim SN, Kishida S, Kishida M, Nakamura N, Kibe T, Harun MH.
Cytotoxic Effects of Betel Quid and Areca Nut Aqueous Extracts on Mouse Fibroblast, Human Mouth-Ordinary-Epithelium 1 and Human Oral Squamous Cell Carcinoma Cell Lines
Asian Pac J Cancer Prev
2020
21(4):1005-1009
PubMed ID: 32334462
DOI: 10.31557/APJCP.2020.21.4.1005
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13783
Otsuki Y, Yamasaki J, Suina K, Okazaki S, Koike N, Saya H, Nagano O.
Vasodilator oxyfedrine inhibits aldehyde metabolism and thereby sensitizes cancer cells to xCT-targeted therapy
Cancer Sci
2020
111(1):127-136.
PubMed ID: 31692172
DOI: 10.1111/cas.14224
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13853
Rizwan Mahmood, Jawaad Ahmed Asif, Wan Nazatul, Shima Shahidan
Stingless-bee (Trigona itama) honey adversely impacts the growth of oral squamous cell carcinoma cell lines (HSC-2)
European Journal of Integrative Medicine
2020
37
DOI: 10.1016/j.eujim.2020.101162
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13903
Aika Tanzawa et al.
Comprehensive gene expression analysis of semaphorins in oral squamous cell carcinoma
Oral Science International
2020
17(2):67-72
DOI: 10.1002/osi2.1044
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11300
Shimizu R, Ibaragi S, Eguchi T, Kuwajima D, Kodama S, Nishioka T, Okui T, Obata K, Takabatake K, Kawai H, Ono K, Okamoto K, Nagatsuka H, Sasaki A.
Nicotine promotes lymph node metastasis and cetuximab resistance in head and neck squamous cell carcinoma.
Int. J. Oncol.
2019
PubMed ID: 30431077
DOI: 10.3892/ijo.2018.4631
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11354
Nakamura Y, Nakahata S, Kondo Y, Izumi A, Yamamoto K, Ichikawa T, Tamura T, Noumi K, Yamashita Y, Morishita K.
Overexpression of absent in melanoma 2 in oral squamous cell carcinoma contributes to tumor progression.
Biochem. Biophys. Res. Commun.
2019
PubMed ID: 30587341
DOI: 10.1016/j.bbrc.2018.12.066
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11363
Nishioka T, Tada H, Ibaragi S, Chen C, Sasano T.
Nicotine exposure induces the proliferation of oral cancer cells through the α7 subunit of the nicotinic acetylcholine receptor.
Biochem. Biophys. Res. Commun.
2019
PubMed ID: 30598264
DOI: 10.1016/j.bbrc.2018.12.154
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11620
Imanari K, Hashimoto M, Wakabayashi H, Okudaira N, Bandow K, Nagai J, Tomomura M, Tomomura A, Uesawa Y, Sakagami H.
Quantitative Structure-Cytotoxicity Relationship of Azulene Amide Derivatives.
Anticancer Res.
2019
PubMed ID: 31262875
DOI: 10.21873/anticanres.13497
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6911
Tabata A, Yamada T, Ohtani H, Ohkura K, Tomoyasu T, Nagamune H.
β-Hemolytic Streptococcus anginosus subsp. anginosus causes streptolysin S-dependent cytotoxicity to human cell culture lines in vitro.
J Oral Microbiol
2019
11(1):1609839.
PubMed ID: 31105901
DOI: 10.1080/20002297.2019.1609839
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9696
Kazuya Hiroshima, Masashi Shiiba, Noritoshi Oka, Fumihiko Hayashi, Sho Ishida, Reo Fukushima, Kazuyuki Koike, Manabu Iyoda, Dai Nakashima, Hideki Tanzawa, Katsuhiro Uzawa
Tspan15 Plays a Crucial Role in Metastasis in Oral Squamous Cell Carcinoma
Exp Cell Res
2019
384(2):111622
PubMed ID: 31518558
DOI: 10.1016/j.yexcr.2019.111622
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9726
Mohamed A A Orabi, Esam A Orabi, Shoko Taniguchi, Hiroshi Sakagami, Morio Yoshimura, Yoshiaki Amakura, Tsutomu Hatano
Structures, NMR Spectroscopic Features, and Cytotoxic Properties of Oligomeric Hellinoyl ( m-GO- m-GOG)-Type Ellagitannins From the Galls of Tamarix aphylla
J Nat Prod
2019
82(10):2682-2695
PubMed ID: 31532650
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Noritoshi Oka, Atsushi Kasamatsu, Yosuke Endo-Sakamoto, Keitaro Eizuka, Sho Wagai, Nao Koide-Ishida, Isao Miyamoto, Manabu Iyoda, Hideki Tanzawa, Katsuhiro Uzawa
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Dis. Markers
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In Vitro Assessment of Antitumor Potential and Combination Effect of Classical and Molecular-targeted Anticancer Drugs.
Anticancer Res.
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Quantitative Structure-Cytotoxicity Relationship of 2-Arylazolylchromones and 2-Triazolylchromones.
Anticancer Res.
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Synthesis, cytotoxicities, and carbonic anhydrase inhibition potential of 6-(3-aryl-2-propenoyl)-2( 3H)-benzoxazolones
J Enzyme Inhib Med Chem
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Eizuka K, Nakashima D, Oka N, Wagai S, Takahara T, Saito T, Koike K, Kasamatsu A, Shiiba M, Tanzawa H, Uzawa K.
SYT12 plays a critical role in oral cancer and may be a novel therapeutic target
J Cancer
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Okazaki S, Umene K, Yamasaki J, Suina K, Otsuki Y, Yoshikawa M, Minami Y, Masuko T, Kawaguchi S, Nakayama H, Banno K, Aoki D, Saya H, Nagano O.
Glutaminolysis-related genes determine sensitivity to xCT-targeted therapy in head and neck squamous cell carcinoma
Cancer Sci
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Non-thermal plasma specifically kills oral squamous cell carcinoma cells in a catalytic Fe(II)-dependent manner
J Clin Biochem Nutr
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Kawano S, Ito K, Yahata K, Kira K, Abe T, Akagi T, Asano M, Iso K, Sato Y, Matsuura F, Ohashi I, Matsumoto Y, Isomura M, Sasaki T, Fukuyama T, Miyashita Y, Kaburagi Y, Yokoi A, Asano O, Owa T, Kishi Y.
A landmark in drug discovery based on complex natural product synthesis
Sci Rep
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9(1):8656
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Yamali C, Gul HI, Ece A, Bua S, Angeli A, Sakagami H, Sahin E, Supuran CT.
Synthesis, biological evaluation and in silico modelling studies of 1,3,5-trisubstituted pyrazoles carrying benzenesulfonamide as potential anticancer agents and selective cancer-associated hCA IX isoenzyme inhibitors
Bioorg Chem
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Crystalline structure of pulverized dental calculus induces cell death in oral epithelial cells.
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Evaluation of tryptophan-aspartic acid repeat-containing protein 34 as a novel tumor-suppressor molecule in human oral cancer.
Biochem. Biophys. Res. Commun.
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Genome-wide identification of chromatin-enriched RNA reveals that unspliced dentin matrix protein-1 mRNA regulates cell proliferation in squamous cell carcinoma.
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Quantitative Structure-Cytotoxicity Relationship of Cinnamic Acid Phenetyl Esters.
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Wada T, Maruyama R, Irie Y, Hashimoto M, Wakabayashi H, Okudaira N, Uesawa Y, Kagaya H, Sakagami H.
In Vitro Anti-tumor Activity of Azulene Amide Derivatives.
In Vivo
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32:479-486
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Quantitative Structure-Cytotoxicity Relationship of Furo[2,3-b]chromones.
Anticancer Res.
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Hara Y, Sakagami H, Shi H, Abe T, Tamura N, Takeshima H, Horie N, Kaneko T, Shiratsuchi H, Kaneko T.
Partial Protection of Paclitaxel-induced Neurotoxicity by Antioxidants.
In Vivo
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Shi H, Nagai J, Sakatsume T, Bandow K, Okudaira N, Sakagami H, Tomomura M, Tomomura A, Uesawa Y, Takao K, Sugita Y.
Quantitative Structure-Cytotoxicity Relationship of 2-(N-cyclicamino)chromone Derivatives.
Anticancer Res.
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Quantitative Structure-Cytotoxicity Relationship of Pyrano[4,3-b]chromones.
Anticancer Res.
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Quantitative Structure-Cytotoxicity Relationship of 3-(N-Cyclicamino)chromone Derivatives.
Anticancer Res.
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Treatment with Lactobacillus Retards the Tumor Growth of Head and Neck Squamous Cell Carcinoma Cells Inoculated in Mice.
Tohoku J. Exp. Med.
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Overexpression of Translocation Associated Membrane Protein 2 Leading to Cancer-Associated Matrix Metalloproteinase Activation as a Putative Metastatic Factor for Human Oral Cancer.
J Cancer
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Sakagami H, Sugimoto M, Kanda Y, Murakami Y, Amano O, Saitoh J, Kochi A.
Changes in Metabolic Profiles of Human Oral Cells by Benzylidene Ascorbates and Eugenol.
Medicines (Basel)
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PubMed ID: 30384403
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Halise Inci, Cem Yamali, Gulsen Gunesacar, Hiroshi Sakagami, Noriyuki Okudaira, Yoshihiro Uesawa, Hajime Kagaya
Cytotoxicity, apoptosis, and QSAR studies of phenothiazine derived methoxylated chalcones as anticancer drug candidates
Medicinal Chemistry Research
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Uehara M, Minemura H, Ohno T, Hashimoto M, Wakabayashi H, Okudaira N, Sakagami H.
In Vitro Antitumor Activity of Alkylaminoguaiazulenes.
In Vivo
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PubMed ID: 29695558
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Okazaki S, Shintani S, Hirata Y, Suina K, Semba T, Yamasaki J, Umene K, Ishikawa M, Saya H, Nagano O.
Synthetic lethality of the ALDH3A1 inhibitor dyclonine and xCT inhibitors in glutathione deficiency-resistant cancer cells.
Oncotarget
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Combined SN-38 and gefitinib treatment promotes CD44 degradation in head and neck squamous cell carcinoma cells.
Oncol. Rep.
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Low carbonyl reductase 1 expression is associated with poor prognosis in patients with oral squamous cell carcinoma.
Mol Clin Oncol
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Long non-coding RNA H1 promotes cell proliferation and invasion by acting as a ceRNA of miR‑138 and releasing EZH2 in oral squamous cell carcinoma.
Int. J. Oncol.
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Influence of excess branched-chain amino acid uptake by Streptococcus mutans in human host cells
FEMS Microbiol Lett
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ERK-dependent IL-6 autocrine signaling mediates adaptive resistance to pan-PI3K inhibitor BKM120 in head and neck squamous cell carcinoma
Oncogene
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SIPA1 promotes invasion and migration in human oral squamous cell carcinoma by ITGB1 and MMP7.
Exp. Cell Res.
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Evidence for Critical Role of Lymphocyte Cytosolic Protein 1 in Oral Cancer.
Sci Rep
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TEAD4-YAP interaction regulates tumoral growth by controlling cell-cycle arrest at the G1 phase.
Biochem. Biophys. Res. Commun.
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Sakagami H, Okudaira N, Masuda Y, Amano O, Yokose S, Kanda Y, Suguro M, Natori T, Oizumi H, Oizumi T.
Induction of Apoptosis in Human Oral Keratinocyte by Doxorubicin.
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Sakagami H, Masuda Y, Tomomura M, Yokose S, Uesawa Y, Ikezoe N, Asahara D, Takao K, Kanamoto T, Terakubo S, Kagaya H, Nakashima H, Sugita Y.
Quantitative Structure-Cytotoxicity Relationship of Chalcones.
Anticancer Res.
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Shimozu Y, Kimura Y, Esumi A, Aoyama H, Kuroda T, Sakagami H, Hatano T.
Ellagitannins of Davidia involucrata. I. Structure of Davicratinic Acid A and Effects of Davidia Tannins on Drug-Resistant Bacteria and Human Oral Squamous Cell Carcinomas.
Molecules
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Saijo R, Sekiya H, Tamai E, Kurihara KI, Maki J, Sakagami H, Kawase M.
A Novel Methodology for Synthesis of 1,5,6-Trisubstituted 2(1H)-Pyrazinones of Biological Interest.
Chem. Pharm. Bull.
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Miyano K, Cabral H, Miura Y, Matsumoto Y, Mochida Y, Kinoh H, Iwata C, Nagano O, Saya H, Nishiyama N, Kataoka K, Yamasoba T.
cRGD peptide installation on cisplatin-loaded nanomedicines enhances efficacy against locally advanced head and neck squamous cell carcinoma bearing cancer stem-like cells.
J Control Release
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Suzuki R, Sakagami H, Amano S, Fukuchi K, Sunaga K, Kanamoto T, Terakubo S, Nakashima H, Shirataki Y, Tomomura M, Masuda Y, Yokose S, Tomomura A, Watanabe H, Okawara M, Matahira Y.
Evaluation of Biological Activity of Mastic Extracts Based on Chemotherapeutic Indices.
In Vivo
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31:591-598
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Takada H, Ibaragi S, Eguchi T, Okui T, Obata K, Masui M, Morisawa A, Takabatake K, Kawai H, Yoshioka N, Hassan NMM, Shimo T, Hu GF, Nagatsuka H, Sasaki A.
Semaphorin 4D promotes bone invasion in head and neck squamous cell carcinoma.
Int. J. Oncol.
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Kita A, Kasamatsu A, Nakashima D, Endo-Sakamoto Y, Ishida S, Shimizu T, Kimura Y, Miyamoto I, Yoshimura S, Shiiba M, Tanzawa H, Uzawa K.
Activin B Regulates Adhesion, Invasiveness, and Migratory Activities in Oral Cancer: a Potential Biomarker for Metastasis.
J Cancer
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Quantitative Structure-Cytotoxicity Relationship of Aurones.
Anticancer Res.
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Quantitative Structure-Cytotoxicity Relationship of Newly Synthesized Piperic Acid Esters.
Anticancer Res.
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Role of Neurokinin 3 Receptor Signaling in Oral Squamous Cell Carcinoma.
Anticancer Res.
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Matsuo Y, Shinoda D, Nakamaru A, Kamohara K, Sakagami H, Mimaki Y.
Steroidal Glycosides from Convallaria majalis Whole Plants and Their Cytotoxic Activity.
Int J Mol Sci
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Increased Expression of CD44v9, A Cancer Stem Cell Marker, in Head And Neck Squamous Cell Carcinoma Cells after Irradiation
Int J Cancer Oncol
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Proteomic and histopathological characterization of the interface between oral squamous cell carcinoma invasion fronts and non-cancerous epithelia.
Exp Mol Pathol
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Real-time monitoring system for evaluating the acid-producing activity of oral squamous cell carcinoma cells at different environmental pH.
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Biochem Biophys Res Commun
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Loss of NDRG2 Expression Confers Oral Squamous Cell Carcinoma with Enhanced Metastatic Potential
Cancer Res
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Gimeracil enhances the antitumor effect of cisplatin in oral squamous cell carcinoma cells in vitro and in vivo
Oncol Lett
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Quest for Cells Responsible for Age-related Increase of Salivary Glycine and Proline.
In Vivo
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Tie2 Regulates Tumor Metastasis of Oral Squamous Cell Carcinomas.
J Cancer
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ARNT2 Regulates Tumoral Growth in Oral Squamous Cell Carcinoma.
J Cancer
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Eradication of CD44-variant positive population in head and neck tumors through controlled intracellular navigation of cisplatin-loaded nanomedicines.
J Control Release
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BMC Cancer
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Enhancement of Cytotoxicity of Three Apoptosis-inducing Agents Against Human Oral Squamous Cell Carcinoma Cell Line by Benzoxazinotropone.
In Vivo
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Antiviral and Antitumor Activity of Licorice Root Extracts.
In Vivo
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J Nat Med
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Int J Mol Sci
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Biomed Res
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Anticancer Res
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Quantitative structure-activity relationship analysis of cytotoxicity and anti-UV activity of 2-aminotropones.
Anticancer Res
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WWP2 is overexpressed in human oral cancer, determining tumor size and poor prognosis in patients: downregulation of WWP2 inhibits the AKT signaling and tumor growth in mice
Oncoscience
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Acta Med Okayama
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In Vivo
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Anticancer Res
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Int J Oncol
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Overexpression of CDCA2 in human squamous cell carcinoma: correlation with prevention of G1 phase arrest and apoptosis.
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J Oral Pathol Med
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Lewis y antigen is expressed in oral squamous cell carcinoma cell lines and tissues, but disappears in the invasive regions leading to the enhanced malignant properties irrespective of sialyl-Lewis x.
Glycoconj J
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Glutamate acid decarboxylase 1 promotes metastasis of human oral cancer by β-catenin translocation and MMP7 activation.
BMC Cancer
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EGFR inhibitors augment antitumour helper T-cell responses of HER family-specific immunotherapy.
Br J Cancer
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Knockdown of Dkk-3 decreases cancer cell migration and invasion independently of the Wnt pathways in oral squamous cell carcinoma‑derived cells
Oncol Rep
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Int J Oncol
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Alternative & Integrative Medicine
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Microbes Infect
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Tumour Biol
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Toxicology
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Effect of CO2 laser irradiation on hormesis induction in cultured oral cells.
In Vivo
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Nat Prod Commun
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Oncol Rep
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Friend leukaemia insertion (Fli)-1 is a prediction marker candidate for radiotherapy resistant oral squamous cell carcinoma
Int J Oral Maxillofac Surg
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Hormetic response of cultured normal and tumor cells to 2-aminotropone derivatives.
In Vivo
2010
24(1):39-44
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Pili of oral Streptococcus sanguinis bind to fibronectin and contribute to cell adhesion.
Biochem Biophys Res Commun
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Biochem Biophys Res Commun
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Oncol Rep
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Anticancer Res
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Anticancer Res
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Anticancer Res
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Hum Cell
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Comparative analysis of cell death induction by cisplatin and 5-FU in human oral squamous and hepatocellular carcinoma cell lines.
Anticancer Res
2008
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Anticancer Res
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Cancer Sci
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