| User's Publication |
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11965
Fujii S, Tajiri Y, Hasegawa K, Matsumoto S, Yoshimoto RU, Wada H, Kishida S, Kido MA, Yoshikawa H, Ozeki S, Kiyoshima T.
The TRPV4-AKT axis promotes oral squamous cell carcinoma cell proliferation via CaMKII activation.
Lab. Invest.
2020
PubMed ID: 31857698
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12037
Nakagawa F, Higashi S, Ando E, Ohsumi T, Watanabe S, Takeuchi H.
Modification of TRPV4 activity by acetaminophen.
Heliyon
2020
PubMed ID: 32051870
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11300
Shimizu R, Ibaragi S, Eguchi T, Kuwajima D, Kodama S, Nishioka T, Okui T, Obata K, Takabatake K, Kawai H, Ono K, Okamoto K, Nagatsuka H, Sasaki A.
Nicotine promotes lymph node metastasis and cetuximab resistance in head and neck squamous cell carcinoma.
Int. J. Oncol.
2019
PubMed ID: 30431077
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11354
Nakamura Y, Nakahata S, Kondo Y, Izumi A, Yamamoto K, Ichikawa T, Tamura T, Noumi K, Yamashita Y, Morishita K.
Overexpression of absent in melanoma 2 in oral squamous cell carcinoma contributes to tumor progression.
Biochem. Biophys. Res. Commun.
2019
PubMed ID: 30587341
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11363
Nishioka T, Tada H, Ibaragi S, Chen C, Sasano T.
Nicotine exposure induces the proliferation of oral cancer cells through the α7 subunit of the nicotinic acetylcholine receptor.
Biochem. Biophys. Res. Commun.
2019
PubMed ID: 30598264
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11620
Imanari K, Hashimoto M, Wakabayashi H, Okudaira N, Bandow K, Nagai J, Tomomura M, Tomomura A, Uesawa Y, Sakagami H.
Quantitative Structure-Cytotoxicity Relationship of Azulene Amide Derivatives.
Anticancer Res.
2019
PubMed ID: 31262875
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11844
Sakurai K, Tomihara K, Yamazaki M, Heshiki W, Moniruzzaman R, Sekido K, Tachinami H, Ikeda A, Imaue S, Fujiwara K, Noguchi M.
CD36 expression on oral squamous cell carcinoma cells correlates with enhanced proliferation and migratory activity.
Oral Dis
2019
PubMed ID: 31603606
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9696
Kazuya Hiroshima, Masashi Shiiba, Noritoshi Oka, Fumihiko Hayashi, Sho Ishida, Reo Fukushima, Kazuyuki Koike, Manabu Iyoda, Dai Nakashima, Hideki Tanzawa, Katsuhiro Uzawa
Tspan15 Plays a Crucial Role in Metastasis in Oral Squamous Cell Carcinoma
Exp Cell Res
2019
384(2):111622
PubMed ID: 31518558
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9726
Mohamed A A Orabi, Esam A Orabi, Shoko Taniguchi, Hiroshi Sakagami, Morio Yoshimura, Yoshiaki Amakura, Tsutomu Hatano
Structures, NMR Spectroscopic Features, and Cytotoxic Properties of Oligomeric Hellinoyl ( m-GO- m-GOG)-Type Ellagitannins From the Galls of Tamarix aphylla
J Nat Prod
2019
82(10):2682-2695
PubMed ID: 31532650
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9890
Noritoshi Oka, Atsushi Kasamatsu, Yosuke Endo-Sakamoto, Keitaro Eizuka, Sho Wagai, Nao Koide-Ishida, Isao Miyamoto, Manabu Iyoda, Hideki Tanzawa, Katsuhiro Uzawa
Centromere Protein N Participates in Cellular Proliferation of Human Oral Cancer by Cell-Cycle Enhancement
J Cancer
2019
10(16):3728-3734
PubMed ID: 31333790
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11907
Cervino G, Fiorillo L, Herford AS, Romeo U, Bianchi A, Crimi S, D'Amico C, De Stefano R, Troiano G, Santoro R, Laino L, Laino G, Cicciù M.
Molecular Biomarkers Related to Oral Carcinoma: Clinical Trial Outcome Evaluation in a Literature Review.
Dis. Markers
2019
PubMed ID: 31019584
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11931
Iijima Y, Bandow K, Sano M, Hino S, Kaneko T, Horie N, Sakagami H.
In Vitro Assessment of Antitumor Potential and Combination Effect of Classical and Molecular-targeted Anticancer Drugs.
Anticancer Res.
2019
PubMed ID: 31810932
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11933
Nagai J, Shi H, Sezaki N, Yoshida N, Bandow K, Uesawa Y, Sakagami H, Tomomura M, Tomomura A, Takao K, Sugita Y.
Quantitative Structure-Cytotoxicity Relationship of 2-Arylazolylchromones and 2-Triazolylchromones.
Anticancer Res.
2019
PubMed ID: 31810912
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10618
Ziauddin SM, Yoshimura A, Montenegro Raudales JL, Ozaki Y, Higuchi K, Ukai T, Kaneko T, Miyazaki T, Latz E, Hara Y.
Crystalline structure of pulverized dental calculus induces cell death in oral epithelial cells.
J. Periodont. Res.
2018
53:353-361
PubMed ID: 29159877
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10682
Yamamoto JI, Kasamatsu A, Okubo Y, Nakashima D, Fushimi K, Minakawa Y, Kasama H, Shiiba M, Tanzawa H, Uzawa K.
Evaluation of tryptophan-aspartic acid repeat-containing protein 34 as a novel tumor-suppressor molecule in human oral cancer.
Biochem. Biophys. Res. Commun.
2018
495:2469-2474
PubMed ID: 29278705
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10683
Suzuki S, Hoshino H, Yoshida K, Nakanishi J, Tsuchiya-Hirata S, Kobuke S, Haruyama N, Nishimura F, Shiba H.
Genome-wide identification of chromatin-enriched RNA reveals that unspliced dentin matrix protein-1 mRNA regulates cell proliferation in squamous cell carcinoma.
Biochem. Biophys. Res. Commun.
2018
495:2303-2309
PubMed ID: 29278708
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10724
Uesawa Y, Sakagami H, Okudaira N, Toda K, Takao K, Kagaya H, Sugita Y.
Quantitative Structure-Cytotoxicity Relationship of Cinnamic Acid Phenetyl Esters.
Anticancer Res.
2018
38:817-823
PubMed ID: 29374707
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10727
Sakagami H, Okudaira N, Uesawa Y, Takao K, Kagaya H, Sugita Y.
Quantitative Structure-Cytotoxicity Relationship of 2-Azolylchromones.
Anticancer Res.
2018
38:763-770
PubMed ID: 29374700
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10806
Okubo Y, Kasamatsu A, Yamatoji M, Fushimi K, Ishigami T, Shimizu T, Kasama H, Shiiba M, Tanzawa H, Uzawa K.
Diacylglycerol lipase alpha promotes tumorigenesis in oral cancer by cell-cycle progression.
Exp. Cell Res.
2018
367:112-118
PubMed ID: 29614312
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10829
Wada T, Maruyama R, Irie Y, Hashimoto M, Wakabayashi H, Okudaira N, Uesawa Y, Kagaya H, Sakagami H.
In Vitro Anti-tumor Activity of Azulene Amide Derivatives.
In Vivo
2018
32:479-486
PubMed ID: 29695549
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11086
Uesawa Y, Sakagami H, Shi H, Hirose M, Takao K, Sugita Y.
Quantitative Structure-Cytotoxicity Relationship of Furo[2,3-b]chromones.
Anticancer Res.
2018
38(6):3283-3290
PubMed ID: 29848675
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11110
Hara Y, Sakagami H, Shi H, Abe T, Tamura N, Takeshima H, Horie N, Kaneko T, Shiratsuchi H, Kaneko T.
Partial Protection of Paclitaxel-induced Neurotoxicity by Antioxidants.
In Vivo
2018
32(4):745-752
PubMed ID: 29936454
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11115
Shi H, Nagai J, Sakatsume T, Bandow K, Okudaira N, Sakagami H, Tomomura M, Tomomura A, Uesawa Y, Takao K, Sugita Y.
Quantitative Structure-Cytotoxicity Relationship of 2-(N-cyclicamino)chromone Derivatives.
Anticancer Res.
2018
38(7):3897-3906
PubMed ID: 29970510
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11147
Nagai J, Shi H, Kubota Y, Bandow K, Okudaira N, Uesawa Y, Sakagami H, Tomomura M, Tomomura A, Takao K, Sugita Y.
Quantitative Structure-Cytotoxicity Relationship of Pyrano[4,3-b]chromones.
Anticancer Res.
2018
38(8):4449-4457
PubMed ID: 30061209
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11148
Shi H, Nagai J, Sakatsume T, Bandow K, Okudaira N, Uesawa Y, Sakagami H, Tomomura M, Tomomura A, Takao K, Sugita Y.
Quantitative Structure-Cytotoxicity Relationship of 3-(N-Cyclicamino)chromone Derivatives.
Anticancer Res.
2018
38(8):4459-4467
PubMed ID: 30061210
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11192
Miyaguchi J, Shiga K, Ogawa K, Suzuki F, Katagiri K, Saito D, Ikeda A, Horii A, Watanabe M, Igimi S.
Treatment with Lactobacillus Retards the Tumor Growth of Head and Neck Squamous Cell Carcinoma Cells Inoculated in Mice.
Tohoku J. Exp. Med.
2018
245(4):269-275
PubMed ID: 30158369
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11226
Fukushima R, Kasamatsu A, Nakashima D, Higo M, Fushimi K, Kasama H, Endo-Sakamoto Y, Shiiba M, Tanzawa H, Uzawa K.
Overexpression of Translocation Associated Membrane Protein 2 Leading to Cancer-Associated Matrix Metalloproteinase Activation as a Putative Metastatic Factor for Human Oral Cancer.
J Cancer
2018
PubMed ID: 30271493
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11272
Sakagami H, Sugimoto M, Kanda Y, Murakami Y, Amano O, Saitoh J, Kochi A.
Changes in Metabolic Profiles of Human Oral Cells by Benzylidene Ascorbates and Eugenol.
Medicines (Basel)
2018
PubMed ID: 30384403
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4078
Halise Inci, Cem Yamali, Gulsen Gunesacar, Hiroshi Sakagami, Noriyuki Okudaira, Yoshihiro Uesawa, Hajime Kagaya
Cytotoxicity, apoptosis, and QSAR studies of phenothiazine derived methoxylated chalcones as anticancer drug candidates
Medicinal Chemistry Research
2018
27:2366–2378
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4173
Uehara M, Minemura H, Ohno T, Hashimoto M, Wakabayashi H, Okudaira N, Sakagami H.
In Vitro Antitumor Activity of Alkylaminoguaiazulenes.
In Vivo
2018
PubMed ID: 29695558
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4235
Okazaki S, Shintani S, Hirata Y, Suina K, Semba T, Yamasaki J, Umene K, Ishikawa M, Saya H, Nagano O.
Synthetic lethality of the ALDH3A1 inhibitor dyclonine and xCT inhibitors in glutathione deficiency-resistant cancer cells.
Oncotarget
2018
PubMed ID: 30333913
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4236
Nanbu T, Umemura N, Ohkoshi E, Nanbu K, Sakagami H, Shimada J.
Combined SN-38 and gefitinib treatment promotes CD44 degradation in head and neck squamous cell carcinoma cells.
Oncol. Rep.
2018
PubMed ID: 29192320
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4237
Yamanouchi R, Harada K, Ferdous T, Ueyama Y.
Low carbonyl reductase 1 expression is associated with poor prognosis in patients with oral squamous cell carcinoma.
Mol Clin Oncol
2018
PubMed ID: 29456845
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4239
Hong Y, He H, Sui W, Zhang J, Zhang S, Yang D.
Long non-coding RNA H1 promotes cell proliferation and invasion by acting as a ceRNA of miR‑138 and releasing EZH2 in oral squamous cell carcinoma.
Int. J. Oncol.
2018
PubMed ID: 29344674
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10044
Ohkoshi E, Umemura N.
Induced overexpression of CD44 associated with resistance to apoptosis on DNA damage response in human head and neck squamous cell carcinoma cells.
Int. J. Oncol.
2017
50:387-395
PubMed ID: 28035370
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10148
Takahara T, Kasamatsu A, Yamatoji M, Iyoda M, Kasama H, Saito T, Takeuchi S, Endo-Sakamoto Y, Shiiba M, Tanzawa H, Uzawa K.
SIPA1 promotes invasion and migration in human oral squamous cell carcinoma by ITGB1 and MMP7.
Exp. Cell Res.
2017
352:357-363
PubMed ID: 28237246
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10155
Koide N, Kasamatsu A, Endo-Sakamoto Y, Ishida S, Shimizu T, Kimura Y, Miyamoto I, Yoshimura S, Shiiba M, Tanzawa H, Uzawa K.
Evidence for Critical Role of Lymphocyte Cytosolic Protein 1 in Oral Cancer.
Sci Rep
2017
7:43379
PubMed ID: 28230172
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10191
Takeuchi S, Kasamatsu A, Yamatoji M, Nakashima D, Endo-Sakamoto Y, Koide N, Takahara T, Shimizu T, Iyoda M, Ogawara K, Shiiba M, Tanzawa H, Uzawa K.
TEAD4-YAP interaction regulates tumoral growth by controlling cell-cycle arrest at the G1 phase.
Biochem. Biophys. Res. Commun.
2017
486:385-390
PubMed ID: 28315328
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10197
Sakagami H, Okudaira N, Masuda Y, Amano O, Yokose S, Kanda Y, Suguro M, Natori T, Oizumi H, Oizumi T.
Induction of Apoptosis in Human Oral Keratinocyte by Doxorubicin.
Anticancer Res.
2017
37:1023-1029
PubMed ID: 28314260
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10201
Sakagami H, Masuda Y, Tomomura M, Yokose S, Uesawa Y, Ikezoe N, Asahara D, Takao K, Kanamoto T, Terakubo S, Kagaya H, Nakashima H, Sugita Y.
Quantitative Structure-Cytotoxicity Relationship of Chalcones.
Anticancer Res.
2017
37:1091-1098
PubMed ID: 28314269
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|
10206
Shimozu Y, Kimura Y, Esumi A, Aoyama H, Kuroda T, Sakagami H, Hatano T.
Ellagitannins of Davidia involucrata. I. Structure of Davicratinic Acid A and Effects of Davidia Tannins on Drug-Resistant Bacteria and Human Oral Squamous Cell Carcinomas.
Molecules
2017
22:
PubMed ID: 28294988
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10241
Saijo R, Sekiya H, Tamai E, Kurihara KI, Maki J, Sakagami H, Kawase M.
A Novel Methodology for Synthesis of 1,5,6-Trisubstituted 2(1H)-Pyrazinones of Biological Interest.
Chem. Pharm. Bull.
2017
65:365-372
PubMed ID: 28381677
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10384
Miyano K, Cabral H, Miura Y, Matsumoto Y, Mochida Y, Kinoh H, Iwata C, Nagano O, Saya H, Nishiyama N, Kataoka K, Yamasoba T.
cRGD peptide installation on cisplatin-loaded nanomedicines enhances efficacy against locally advanced head and neck squamous cell carcinoma bearing cancer stem-like cells.
J Control Release
2017
261:275-286
PubMed ID: 28666729
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10386
Suzuki R, Sakagami H, Amano S, Fukuchi K, Sunaga K, Kanamoto T, Terakubo S, Nakashima H, Shirataki Y, Tomomura M, Masuda Y, Yokose S, Tomomura A, Watanabe H, Okawara M, Matahira Y.
Evaluation of Biological Activity of Mastic Extracts Based on Chemotherapeutic Indices.
In Vivo
2017
31:591-598
PubMed ID: 28652425
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|
10395
Takada H, Ibaragi S, Eguchi T, Okui T, Obata K, Masui M, Morisawa A, Takabatake K, Kawai H, Yoshioka N, Hassan NMM, Shimo T, Hu GF, Nagatsuka H, Sasaki A.
Semaphorin 4D promotes bone invasion in head and neck squamous cell carcinoma.
Int. J. Oncol.
2017
51:625-632
PubMed ID: 28656278
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|
10418
Kita A, Kasamatsu A, Nakashima D, Endo-Sakamoto Y, Ishida S, Shimizu T, Kimura Y, Miyamoto I, Yoshimura S, Shiiba M, Tanzawa H, Uzawa K.
Activin B Regulates Adhesion, Invasiveness, and Migratory Activities in Oral Cancer: a Potential Biomarker for Metastasis.
J Cancer
2017
8:2033-2041
PubMed ID: 28819404
|
|
10572
Uesawa Y, Sakagami H, Ikezoe N, Takao K, Kagaya H, Sugita Y.
Quantitative Structure-Cytotoxicity Relationship of Aurones.
Anticancer Res.
2017
37:6169-6176
PubMed ID: 29061798
|
|
10576
Sakagami H, Uesawa Y, Masuda Y, Tomomura M, Yokose S, Miyashiro T, Murai J, Takao K, Kanamoto T, Terakubo S, Kagaya H, Nakashima H, Sugita Y.
Quantitative Structure-Cytotoxicity Relationship of Newly Synthesized Piperic Acid Esters.
Anticancer Res.
2017
37:6161-6168
PubMed ID: 29061797
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|
10579
Obata K, Shimo T, Okui T, Matsumoto K, Takada H, Takabatake K, Kunisada Y, Ibaragi S, Yoshioka N, Kishimoto K, Nagatsuka H, Sasaki A.
Role of Neurokinin 3 Receptor Signaling in Oral Squamous Cell Carcinoma.
Anticancer Res.
2017
37:6119-6123
PubMed ID: 29061792
|
|
10600
Matsuo Y, Shinoda D, Nakamaru A, Kamohara K, Sakagami H, Mimaki Y.
Steroidal Glycosides from Convallaria majalis Whole Plants and Their Cytotoxic Activity.
Int J Mol Sci
2017
18:
PubMed ID: 29112119
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|
11036
Increased Expression of CD44v9, A Cancer Stem Cell Marker, in Head And Neck Squamous Cell Carcinoma Cells after Irradiation
Int J Cancer Oncol
2017
4: 225- 230
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6025
Abé T, Maruyama S, Yamazaki M, Xu B, Babkair H, Sumita Y, Cheng J, Yamamoto T, Saku T.
Proteomic and histopathological characterization of the interface between oral squamous cell carcinoma invasion fronts and non-cancerous epithelia.
Exp Mol Pathol
2017
102(2):327-336
PubMed ID: 28242296
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6026
Morishima H, Washio J, Kitamura J, Shinohara Y, Takahashi T, Takahashi N.
Real-time monitoring system for evaluating the acid-producing activity of oral squamous cell carcinoma cells at different environmental pH.
Sci Rep.
2017
7(1):10092
PubMed ID: 28855722
|
|
6029
Ishida S et al
Novel mechanism of aberrant ZIP4 expression with zinc supplementation in oral tumorigenesis.
Biochem Biophys Res Commun
2017
483(1):339-345
PubMed ID: 28017725
|
|
9584
Hino S, Nishiyama A, Matsuta T, Horie N, Shimoyama T, Tanaka S, Sakagami H.
Quest for Cells Responsible for Age-related Increase of Salivary Glycine and Proline.
In Vivo
2016
30:91-7
PubMed ID: 26912818
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|
9616
Kitajima D, Kasamatsu A, Nakashima D, Miyamoto I, Kimura Y, Saito T, Suzuki T, Endo-Sakamoto Y, Shiiba M, Tanzawa H, Uzawa K.
Tie2 Regulates Tumor Metastasis of Oral Squamous Cell Carcinomas.
J Cancer
2016
7:600-7
PubMed ID: 27053959
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|
9630
Kimura Y, Kasamatsu A, Nakashima D, Yamatoji M, Minakawa Y, Koike K, Fushimi K, Higo M, Endo-Sakamoto Y, Shiiba M, Tanzawa H, Uzawa K.
ARNT2 Regulates Tumoral Growth in Oral Squamous Cell Carcinoma.
J Cancer
2016
7:702-10
PubMed ID: 27076852
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|
9640
Wang M, Miura Y, Tsuchihashi K, Miyano K, Nagano O, Yoshikawa M, Tanabe A, Makino J, Mochida Y, Nishiyama N, Saya H, Cabral H, Kataoka K.
Eradication of CD44-variant positive population in head and neck tumors through controlled intracellular navigation of cisplatin-loaded nanomedicines.
J Control Release
2016
230:26-33
PubMed ID: 27040816
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|
9694
Harada K, Ferdous T, Harada T, Ueyama Y.
Metformin in combination with 5-fluorouracil suppresses tumor growth by inhibiting the Warburg effect in human oral squamous cell carcinoma.
Int. J. Oncol.
2016
49:276-84
PubMed ID: 27210058
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|
9770
Harada K, Ferdous T, Cui D, Kuramitsu Y, Matsumoto T, Ikeda E, Okano H, Ueyama Y.
Induction of artificial cancer stem cells from tongue cancer cells by defined reprogramming factors.
BMC Cancer
2016
16:548
PubMed ID: 27464948
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|
9808
Tomikoshi Y, Nomura M, Okudaira N, Sakagami H, Wakabayashi H.
Enhancement of Cytotoxicity of Three Apoptosis-inducing Agents Against Human Oral Squamous Cell Carcinoma Cell Line by Benzoxazinotropone.
In Vivo
2016
30:645-50
PubMed ID: 27566085
|
|
9892
Uesawa Y, Sakagami H, Kagaya H, Yamashita M, Takao K, Sugita Y.
Quantitative Structure-cytotoxicity Relationship of 3-Benzylidenechromanones.
Anticancer Res.
2016
36:5803-5812
PubMed ID: 27793902
|
|
9896
Suzuki R, Matsushima Y, Okudaira N, Sakagami H, Shirataki Y.
Cytotoxic Components Against Human Oral Squamous Cell Carcinoma Isolated from Andrographis paniculata.
Anticancer Res.
2016
36:5931-5935
PubMed ID: 27793918
|
|
9900
Harada K, Ferdous T, Ueyama Y.
Gimeracil Exerts Radiosensitizing Effects on Oral Squamous Cell Carcinoma Cells In Vitro and In Vivo.
Anticancer Res.
2016
36:5923-5930
PubMed ID: 27793917
|
|
9911
Fukuchi K, Okudaira N, Adachi K, Odai-Ide R, Watanabe S, Ohno H, Yamamoto M, Kanamoto T, Terakubo S, Nakashima H, Uesawa Y, Kagaya H, Sakagami H.
Antiviral and Antitumor Activity of Licorice Root Extracts.
In Vivo
2016
30:777-785
PubMed ID: 27815461
|
|
5809
Ninomiya K et al
Acylated oleanane-type triterpene saponins from the flowers of Bellis perennis show anti-proliferative activities against human digestive tract carcinoma cell lines.
J Nat Med
2016
70(3):435-51
PubMed ID: 27178360
|
|
6032
Tada H, Shimizu T, Nagaoka I, Takada H.
Vitamin D3 analog maxacalcitol (OCT) induces hCAP-18/LL-37 production in human oral epithelial cells.
Biomed Res
2016
37(3):199-205
PubMed ID: 27356607
|
|
6036
Suzuki T, Kasamatsu A, Miyamoto I, Saito T, Higo M, Endo-Sakamoto Y, Shiiba M, Tanzawa H, Uzawa K.
Overexpression of TMOD1 is associated with enhanced regional lymph node metastasis in human oral cancer.
Int J Oncol.
2016
48(2):607-12
PubMed ID: 26718916
|
|
6042
Unozawa M, Kasamatsu A, Higo M, Fukumoto C, Koyama T, Sakazume T, Nakashima D, Ogawara K, Yokoe H, Shiiba M, Tanzawa H, Uzawa
Cavin-2 in oral cancer: A potential predictor for tumor progression.
Mol Carcinog
2016
55(6):1037-47
PubMed ID: 26086332
|
|
7196
Uesawa Y, Sakagami H, Ishihara M, Kagaya H, Kanamoto T, Terakubo S, Nakashima H, Yahagi H, Takao K, Sugita Y.
Quantitative Structure-Cytotoxicity Relationship of 3-Styryl-2H-chromenes.
Anticancer Res.
2015
35:5299-307
PubMed ID: 26408690
|
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7442
Shirako Y, Taya Y, Sato K, Chiba T, Imai K, Shimazu Y, Aoba T, Soeno Y.
Heterogeneous tumor stromal microenvironments of oral squamous cell carcinoma cells in tongue and nodal metastatic lesions in a xenograft mouse model.
J. Oral Pathol. Med.
2015
44:656-68
PubMed ID: 25765182
|
|
5422
Sakagami H, Uesawa Y, Ishihara M, Kagaya H, Kanamoto T, Terakubo S, Nakashima H, Takao K, Sugita Y5.
Quantitative Structure-Cytotoxicity Relationship of Oleoylamides.
Anticancer Res
2015
5(10):5341-51
PubMed ID: 26408695
|
|
6043
Sakagami H, Shimada C, Kanda Y, Amano O, Sugimoto M, Ota S, Soga T, Tomita M, Sato A, Tanuma SI, Takao K, Sugita Y.
Effects of 3-styrylchromones on metabolic profiles and cell death in oral squamous cell carcinoma cells.
Toxicol Rep
2015
2:1281-1290
PubMed ID: 28962471
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|
6044
Kasama H et al
Adenosine A2b receptor promotes progression of human oral cancer.
BMC Cancer
2015
15:563
PubMed ID: 26228921
|
|
6051
Okamoto A et al
Down-Regulation of Nucleolar and Spindle-Associated Protein 1 (NUSAP1) Expression Suppresses Tumor and Cell Proliferation and Enhances Anti-Tumor Effect of Paclitaxel in Oral Squamous Cell Carcinoma.
PLoS One
2015
10(11):e0142252
PubMed ID: 26554377
|
|
6052
Saito T et al
Semaphorin7A Promotion of Tumoral Growth and Metastasis in Human Oral Cancer by Regulation of G1 Cell Cycle and Matrix Metalloproteases: Possible Contribution to Tumoral Angiogenesis.
PLoS One
2015
10(9):e0137923
PubMed ID: 26378920
|
|
6053
Miyamoto I et al
Kinesin family member 14 in human oral cancer: A potential biomarker for tumoral growth.
Biochem Biophys Rep
2015
3:26-31
PubMed ID: 29124166
|
|
6054
Baba T et al
Persephin: A potential key component in human oral cancer progression through the RET receptor tyrosine kinase-mitogen-activated protein kinase signaling pathway.
Mol Carcinog
2015
54(8):608-17
PubMed ID: 24375483
|
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6058
Shida-Sakazume T et al
Lysophosphatidylcholine acyltransferase1 overexpression promotes oral squamous cell carcinoma progression via enhanced biosynthesis of platelet-activating factor.
PLoS One.
2015
10(3):e0120143
PubMed ID: 25803864
|
|
6056
Suzuki R, Matsuno S, Sakagami H, Okada Y, Shirataki Y.
Search of new cytotoxic crude materials against human oral squamous cell carcinoma using 1H NMR-based metabolomics.
Anticancer Res
2014
34(8):4117-20
PubMed ID: 25075037
|
|
6040
Garcia-Contreras R, Scougall-Vilchis RJ, Contreras-Bulnes R, Ando Y, Kanda Y, Hibino Y, Nakajima H, Sakagami H.
Effects of TiO2 nanoparticles on cytotoxic action of chemotherapeutic drugs against a human oral squamous cell carcinoma cell line.
In Vivo
2014
28(2):209-15
PubMed ID: 24632975
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|
6038
Hiroshi Sakagami et al
Metabolomic profiling of sodium fluoride-induced cytotoxicity in an oral squamous cell carcinoma cell line
Metabolomics
2014
10:270–279
|
|
5916
Garcia-Contreras R, Scougall-Vilchis RJ, Contreras-Bulnes R, Kanda Y, Nakajima H, Sakagami H
Cytotoxicity and pro-inflammatory action of chemo-mechanical caries-removal agents against oral cells.
In Vivo
2014
28(4):549-56
PubMed ID: 24982221
|
|
5859
Miyamoto C, Maehata Y, Motohashi K, Ozawa S, Ikoma T, Hidaka K, Wada-Takahashi S, Takahashi SS, Yoshino F, Yoshida A, Kubota E, Hata R, Lee MC.
Fasudil, a Rho kinase inhibitor, suppresses tumor growth by inducing CXCL14/BRAK in head and neck squamous cell carcinoma.
Biomed Res.
2014
35(6):381-8
PubMed ID: 25743344
|
|
5807
Garcia-Contreras R, Scougall-Vilchis RJ, Contreras-Bulnes R, Kanda Y, Nakajima H, Sakagami H.
Effects of TiO2 nano glass ionomer cements against normal and cancer oral cells.
In Vivo
2014
28(5):895-907
PubMed ID: 25189906
|
|
5778
Ishige S, Kasamatsu A, Ogoshi K, Saito Y, Usukura K, Yokoe H, Kouzu Y, Koike H, Sakamoto Y, Ogawara K, Shiiba M, Tanzawa H, Uzawa K.
Decreased expression of kallikrein-related peptidase 13: possible contribution to metastasis of human oral cancer.
Mol Carcinog
2014
53(7):557-65
PubMed ID: 23371469
|
|
5659
Shimada C, Uesawa Y, Ishii-Nozawa R, Ishihara M, Kagaya H, Kanamoto T, Terakubo S, Nakashima H, Takao K, Sugita Y, Sakagami H.
Quantitative structure-cytotoxicity relationship of 3-styrylchromones.
Anticancer Res
2014
34(10):5405-11
PubMed ID: 25275035
|
|
5605
Iizuka S, Oridate N, Nashimoto M, Fukuda S, Tamura M.
Growth inhibition of head and neck squamous cell carcinoma cells by sgRNA targeting the cyclin D1 mRNA based on TRUE gene silencing.
PLoS One
2014
9(12):e114121
PubMed ID: 25437003
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|
5544
Shimada C, Uesawa Y, Ishihara M, Kagaya H, Kanamoto T, Terakubo S, Nakashima H, Takao K, Saito T, Sugita Y, Sakagami H.
Quantitative structure-cytotoxicity relationship of phenylpropanoid amides.
Anticancer Res
2014
34(7):3543-8
PubMed ID: 24982367
|
|
5337
Shimada C, Uesawa Y, Ishihara M, Kagaya H, Kanamoto T, Terakubo S, Nakashima H, Takao K, Miyashiro T, Sugita Y, Sakagami H.
Quantitative structure-cytotoxicity relationship of piperic acid amides.
Anticancer Res
2014
34(9):4877-84
PubMed ID: 25202069
|
|
5315
Sekine S, Shimodaira C, Uesawa Y, Kagaya H, Kanda Y, Ishihara M, Amano O, Sakagami H, Wakabayashi H.
Quantitative structure-activity relationship analysis of cytotoxicity and anti-UV activity of 2-aminotropones.
Anticancer Res
2014
4(4):1743-50
PubMed ID: 24692705
|
|
5190
Yamamoto M, Fujita H, Katase N, Inoue K, Nagatsuka H, Utsumi K, Sasaki J, Ohuchi H.
Improvement of the efficacy of 5-aminolevulinic acid-mediated photodynamic treatment in human oral squamous cell carcinoma HSC-4.
Acta Med Okayama
2013
67(3):153-64
PubMed ID: 23804138
|
|
5122
Iida S, Shimada J, Sakagami H.
Cytotoxicity induced by docetaxel in human oral squamous cell carcinoma cell lines.
In Vivo
2013
27(3):321-32
PubMed ID: 23606687
|
|
5110
Ohno H, Araho D, Uesawa Y, Kagaya H, Ishihara M, Sakagami H, Yamamoto M.
Evaluation of cytotoxiciy and tumor-specificity of licorice flavonoids based on chemical structure.
Anticancer Res
2013
33(8):3061-8
PubMed ID: 23898061
|
|
5028
Saito Y, Kasamatsu A, Yamamoto A, Shimizu T, Yokoe H, Sakamoto Y, Ogawara K, Shiiba M, Tanzawa H, Uzawa K.
ALY as a potential contributor to metastasis in human oral squamous cell carcinoma.
J Cancer Res Clin Oncol
2013
139(4):585-94
PubMed ID: 23242234
|
|
6065
Miyazaki Y, Fujinami M, Inoue H, Kikuchi K, Ide F, Kusama K.
Expression of activation-induced cytidine deaminase in oral epithelial dysplasia and oral squamous cell carcinoma.
J Oral Sci
2013
55(4):293-9
PubMed ID: 24351917
|
|
6067
Koike K, Kasamatsu A, Iyoda M, Saito Y, Kouzu Y, Koike H, Sakamoto Y, Ogawara K, Tanzawa H, Uzawa K.
High prevalence of epigenetic inactivation of the human four and a half LIM domains 1 gene in human oral cancer.
Int J Oncol
2013
42(1):141-50
PubMed ID: 23123766
|
|
6070
Yamamoto A, Kasamatsu A, Ishige S, Koike K, Saito K, Kouzu Y, Koike H, Sakamoto Y, Ogawara K, Shiiba M, Tanzawa H, Uzawa K.
Exocyst complex component Sec8: a presumed component in the progression of human oral squamous-cell carcinoma by secretion of matrix metalloproteinases.
J Cancer Res Clin Oncol
2013
139(4):533-42
PubMed ID: 23207790
|
|
6072
Uchida F, Uzawa K, Kasamatsu A, Takatori H, Sakamoto Y, Ogawara K, Shiiba M, Bukawa H, Tanzawa H.
Overexpression of CDCA2 in human squamous cell carcinoma: correlation with prevention of G1 phase arrest and apoptosis.
PLoS One
2013
8(2):e56381
PubMed ID: 23418564
|
|
6076
Minakawa Y, Kasamatsu A, Koike H, Higo M, Nakashima D, Kouzu Y, Sakamoto Y, Ogawara K, Shiiba M, Tanzawa H, Uzawa K.
Kinesin family member 4A: a potential predictor for progression of human oral cancer.
PLoS One. 2
2013
8(12):e85951
PubMed ID: 24386490
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|
6077
Mikami T, Hada T, Chosa N, Ishisaki A, Mizuki H, Takeda Y. Author information
Expression of Wilms' tumor 1 (WT1) in oral squamous cell carcinoma.
J Oral Pathol Med
2013
42(2):133-9
PubMed ID: 22672247
|
|
6078
Hotta H, Hamamura K, Yamashita K, Shibuya H, Tokuda N, Hashimoto N, Furukawa K, Yamamoto N, Hattori H, Toyokuni S, Ueda M, Furukawa K.
Lewis y antigen is expressed in oral squamous cell carcinoma cell lines and tissues, but disappears in the invasive regions leading to the enhanced malignant properties irrespective of sialyl-Lewis x.
Glycoconj J
2013
30(6):585-97
PubMed ID: 23242548
|
|
6081
Kimura R, Kasamatsu A, Koyama T, Fukumoto C, Kouzu Y, Higo M, Endo-Sakamoto Y, Ogawara K, Shiiba M, Tanzawa H, Uzawa K.
Glutamate acid decarboxylase 1 promotes metastasis of human oral cancer by β-catenin translocation and MMP7 activation.
BMC Cancer
2013
13:555
PubMed ID: 24261884
|
|
6083
Kumai T, Matsuda Y, Oikawa K, Aoki N, Kimura S, Harabuchi Y, Celis E, Kobayashi H.
EGFR inhibitors augment antitumour helper T-cell responses of HER family-specific immunotherapy.
Br J Cancer
2013
109(8):2155-66
PubMed ID: 24045666
|
|
6087
Miyazaki Y, Inoue H, Kikuchi K, Ochiai K, Kusama K.
Activation-induced cytidine deaminase mRNA expression in oral squamous cell carcinoma-derived cell lines is upregulated by inflammatory cytokines.
J Oral Sci
2012
54(1):71-5
PubMed ID: 22466889
|
|
6088
Baba T, Kawaguchi M, Fukushima T, Sato Y, Orikawa H, Yorita K, Tanaka H, Lin CY, Sakoda S, Kataoka H.
Loss of membrane-bound serine protease inhibitor HAI-1 induces oral squamous cell carcinoma cells' invasiveness.
J Pathol
2012
228(2):181-92
PubMed ID: 22262311
|
|
6089
Inoue H, Miyazaki Y, Kikuchi K, Yoshida N, Ide F, Ohmori Y, Tomomura A, Sakashita H, Kusama K.
Podoplanin promotes cell migration via the EGF-Src-Cas pathway in oral squamous cell carcinoma cell lines.
J Oral Sci
2012
54(3):241-50
PubMed ID: 23047035
|
|
6091
Shimada E, Kataoka H, Miyazawa Y, Yamamoto M, Igarashi T.
Lipoproteins of Actinomyces viscosus induce inflammatory responses through TLR2 in human gingival epithelial cells and macrophages.
Microbes Infect
2012
14(11):916-21
PubMed ID: 22561467
|
|
6095
Katase N, Lefeuvre M, Gunduz M, Gunduz E, Beder LB, Grenman R, Fujii M, Tamamura R, Tsujigiwa H, Nagatsuka H.
Absence of Dickkopf (Dkk)-3 protein expression is correlated with longer disease-free survival and lower incidence of metastasis in head and neck squamous cell carcinoma.
Oncol Lett
2012
3(2):273-280
PubMed ID: 22740894
|
|
6098
Inoue H, Miyazaki Y, Kikuchi K, Yoshida N, Ide F, Ohmori Y, Tomomura A, Sakashita H, Kusama K.
Podoplanin expression during dysplasia-carcinoma sequence in the oral cavity.
Tumour Biol
2012
33(1):183-94
PubMed ID: 22081310
|
|
7601
Uesawa Y, Mohri K, Kawase M, Ishihara M, Sakagami H.
Quantitative structure-activity relationship (QSAR) analysis of tumor-specificity of 1,2,3,4-tetrahydroisoquinoline derivatives.
Anticancer Res.
2011
31:4231-8
PubMed ID: 22199286
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|
7764
Otsuki S, Sugiyama K, Amano O, Yasui T, Sakagami H.
Negative regulation of NaF-induced apoptosis by Bad-CAII complex.
Toxicology
2011
287:131-6
PubMed ID: 21708216
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|
7967
Iwasaka K, Tomita K, Ozawa Y, Katayama T, Sakagami H.
Effect of CO2 laser irradiation on hormesis induction in cultured oral cells.
In Vivo
2011
25:93-8
PubMed ID: 21282740
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|
5323
Jitsuno M, Yokosuka A, Hashimoto K, Amano O, Sakagami H, Mimaki Y.
Chemical constituents of Lycoris albiflora and their cytotoxic activities.
Nat Prod Commun
2011
6(2):187-92
PubMed ID: 21425671
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|
6116
Zhang T, Hamada K, Hyodo M, Itoh H, Tani K, Goda H, Nakashiro K, Hamakawa H.
Gene therapy for oral squamous cell carcinoma with IAI.3B promoter-driven oncolytic adenovirus-infected carrier cells.
Oncol Rep
2011
25(3):795-802
PubMed ID: 21206983
|
|
8085
Sakagami H, Zhou L, Kawano M, Thet MM, Tanaka S, Machino M, Amano S, Kuroshita R, Watanabe S, Chu Q, Wang QT, Kanamoto T, Terakubo S, Nakashima H, Sekine K, Shirataki Y, Zhang CH, Uesawa Y, Mohri K, Kitajima M, Oizumi H, Oizumi T.
Multiple biological complex of alkaline extract of the leaves of Sasa senanensis Rehder.
In Vivo
2010
24:735-43
PubMed ID: 20952742
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|
5611
Wakabayashi H, Narita T, Suga A, Sakagami H.
Hormetic response of cultured normal and tumor cells to 2-aminotropone derivatives.
In Vivo
2010
24(1):39-44
PubMed ID: 20133973
|
|
6119
Okahashi N, Nakata M, Sakurai A, Terao Y, Hoshino T, Yamaguchi M, Isoda R, Sumitomo T, Nakano K, Kawabata S, Ooshima T.
Pili of oral Streptococcus sanguinis bind to fibronectin and contribute to cell adhesion.
Biochem Biophys Res Commun
2010
391(2):1192-6
PubMed ID: 20004645
|
|
6120
Furuta H, Kondo Y, Nakahata S, Hamasaki M, Sakoda S, Morishita K.
NDRG2 is a candidate tumor-suppressor for oral squamous-cell carcinoma.
Biochem Biophys Res Commun
2010
391(4):1785-91
PubMed ID: 20045673
|
|
6122
Nomi N, Kodama S, Suzuki M.
Toll-like receptor 3 signaling induces apoptosis in human head and neck cancer via survivin associated pathway.
Oncol Rep
2010
24(1):225-31
PubMed ID: 20514466
|
|
6123
Yuji Miyazaki et al
Association of butyric acid produced by periodontopathic bacteria with progression of oral cancer
J Cancer Sci Ther
2010
2(2) :26-32
|
|
8406
Okugawa T, Kaneko T, Yoshimura A, Silverman N, Hara Y.
NOD1 and NOD2 mediate sensing of periodontal pathogens.
J. Dent. Res.
2009
89:186-91
PubMed ID: 20040739
|
|
6127
Hatano H, Takekawa F, Hashimoto K, Ishihara M, Kawase M, Qing C, Qin-Tao W, Sakagami H.
Tumor-specific cytotoxic activity of 1,2,3,4-tetrahydroisoquinoline derivatives against human oral squamous cell carcinoma cell lines.
Anticancer Res
2009
29(8):3079-86
PubMed ID: 19661319
|
|
6128
Takano A, Hashimoto K, Ogawa M, Koyanagi J, Kurihara T, Wakabayashi H, Kikuchi H, Nakamura Y, Motohashi N, Sakagami H, Yamamoto K, Tanaka A.
Tumor-specific cytotoxicity and type of cell death induced by naphtho[2,3-b]furan-4,9-diones and related compounds in human tumor cell lines: relationship to electronic structure.
Anticancer Res
2009
29(1):455-64
PubMed ID: 19331186
|
|
6129
Narita T, Suga A, Kobayashi M, Hashimoto K, Sakagami H, Motohashi N, Kurihara T, Wakabayashi H.
Tumor-specific cytotoxicity and type of cell death induced by benzo[b]cyclohept[e][1,4]oxazine and 2-aminotropone derivatives.
Anticancer Res
2009
29(4):1123-30
PubMed ID: 19414354
|
|
6410
Danjoh I, Sone H, Noda N, Iimura E, Nagayoshi M, Saijo K, Hiroyama T, Nakamura Y.
Is parainfluenza virus a threatening virus for human cancer cell lines?
Hum Cell
2009
22(3):81-4
PubMed ID: 19624309
|
|
6136
Okamura M, Shimada J, Sakagami H.
Comparative analysis of cell death induction by cisplatin and 5-FU in human oral squamous and hepatocellular carcinoma cell lines.
Anticancer Res
2008
28(1A):253-9
PubMed ID: 18383853
|
|
6138
Murayama H, Miyahara K, Wakabayashi H, Kurihara T, Hashimoto K, Amano O, Kikuchi H, Nakamura Y, Kanda Y, Kunii S, Motohashi N, Sakagami H.
Tumor-specific cytotoxicity and type of cell death induced by benzocycloheptoxazines in human tumor cell lines.
Anticancer Res
2008
28(2A):1069-78
PubMed ID: 18507056
|
|
6140
Sakagami H, Amano S, Kikuchi H, Nakamura Y, Kuroshita R, Watanabe S, Satoh K, Hasegawa H, Nomura A, Kanamoto T, Terakubo S, Nakashima H, Taniguchi S, Oizumi T.
Antiviral, antibacterial and vitamin C-synergized radical-scavenging activity of Sasa senanensis Rehder extract.
In Vivo
2008
2(4):471-6
PubMed ID: 18712174
|
|
6141
Nakamura E, Kozaki K, Tsuda H, Suzuki E, Pimkhaokham A, Yamamoto G, Irie T, Tachikawa T, Amagasa T, Inazawa J, Imoto I.
Frequent silencing of a putative tumor suppressor gene melatonin receptor 1 A (MTNR1A) in oral squamous-cell carcinoma.
Cancer Sci
2008
99(7):1390-400
PubMed ID: 18452558
|
|
6142
Okamura M, Kobayashi M, Suzuki F, Shimada J, Sakagami H.
Induction of cell death by combination treatment with cisplatin and 5-fluorouracil in a human oral squamous cell carcinoma cell line.
Anticancer Res
2007
27(5A):3331-7
PubMed ID: 17970078
|
|
6143
Sekine T, Takahashi J, Nishishiro M, Arai A, Wakabayashi H, Kurihara T, Kobayashi M, Hashimoto K, Kikuchi H, Katayama T, Kanda Y, Kunii S, Motohashi N, Sakagami H.
Tumor-specificity and type of cell death induced by trihaloacetylazulenes in human tumor cell lines.
Anticancer Res.
2007
27(1A):133-43
PubMed ID: 17352225
|
|
6148
Akatsu Y, Ohshima N, Yamagishi Y, Nishishiro M, Wakabayashi H, Kurihara T, Kikuchi H, Katayama T, Motohashi N, Shoji Y, Nakashima H, Sakagami H.
Apoptosis-inducing activity of trihaloacetylazulenes against human oral tumor cell lines.
Anticancer Res
2006
26(3A):1917-23
PubMed ID: 16827125
|
|
6150
Ichwan SJ, Yamada S, Sumrejkanchanakij P, Ibrahim-Auerkari E, Eto K, Ikeda MA.
Defect in serine 46 phosphorylation of p53 contributes to acquisition of p53 resistance in oral squamous cell carcinoma cells.
Oncogene
2006
25(8):1216-24
PubMed ID: 16247456
|
|
6152
Wakabayashi H, Nishishiro M, Arikawa S, Hashimoto K, Kikuchi H, Nishikawa H, Kurihara T, Terakubo S, Shoji Y, Nakashima H, Motohashi N, Sakagami H.
Cytotoxic activity of azulenequinones against human oral tumor cell lines.
Anticancer Res
2005
25(1A):305-12
PubMed ID: 15816552
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