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21829
Wu MJ, Kondo H, Kammula AV, Shi L, Xiao Y, Dhiab S, Xu Q, Slater CJ, Avila OI, Merritt J, Kato H, Kattel P, Sussman J, Gritti I, Eccleston J, Sun Y, Cho HM, Olander K, Katsuda T, Shi DD, Savani MR, Smith BC, Cleary JM, Mostoslavsky R, Vijay V, Kitagawa Y, Wakimoto H, Jenkins RW, Yates KB, Paik J, Tassinari A, Saatcioglu DH, Tron AE, Haas W, Cahill D, McBrayer SK, Manguso RT, Bardeesy N.
Mutant IDH1 inhibition induces dsDNA sensing to activate tumor immunity.
Science
2024
385(6705):eadl6173
PubMed ID: 38991060
DOI: 10.1126/science.adl6173
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21886
Schüler J, Vockerodt M, Salehzadeh N, Becker J, Wilting J.
Dual Inhibition of PI3 Kinase and MAP Kinase Signaling Pathways in Intrahepatic Cholangiocellular Carcinoma Cell Lines Leads to Proliferation Arrest but Not Apoptosis.
Curr Issues Mol Biol
2024
46(7):7395-7410
PubMed ID: 39057080
DOI: 10.3390/cimb46070439
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21553
Louis C, Ferlier T, Leroux R, Pineau R, Desoteux M, Papoutsoglou P, Leclerc D, Angenard G, Vaquero J, Macias RIR, Edeline J, Coulouarn C.
TGFβ-induced circLTBP2 predicts a poor prognosis in intrahepatic cholangiocarcinoma and mediates gemcitabine resistance by sponging miR-338-3p.
JHEP Rep
2023
5(12):100900
PubMed ID: 38023605
DOI: 10.1016/j.jhepr.2023.100900
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17715
Zhang L, Ma D, Li F, Qiu G, Sun D, Zeng Z.
Lnc-PKD2-2-3/miR-328/GPAM ceRNA Network Induces Cholangiocarcinoma Proliferation, Invasion and 5-FU Chemoresistance
Front Oncol
2022
12:871281
PubMed ID: 35965521
DOI: 10.3389/fonc.2022.871281
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21148
Kosai-Fujimoto Y, Itoh S, Yugawa K, Fukuhara T, Okuzaki D, Toshima T, Harada N, Oda Y, Yoshizumi T, Mori M.
Impact of JMJD6 on intrahepatic cholangiocarcinoma.
Mol Clin Oncol
2022
17(2):131
PubMed ID: 35911665
DOI: 10.3892/mco.2022.2564
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15892
Khorsandi SE, Dokal AD, Rajeeve V, Britton DJ, Illingworth MS, Heaton N, Cutillas PR.
Computational Analysis of Cholangiocarcinoma Phosphoproteomes Identifies Patient-Specific Drug Targets.
Cancer Res
2021
81(22):5765-5776
PubMed ID: 34551960
DOI: 10.1158/0008-5472.CAN-21-0955
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12589
Miyata T, Yamashita YI, Yoshizumi T, Shiraishi M, Ohta M, Eguchi S, Aishima S, Fujioka H, Baba H.
CXCL12 expression in intrahepatic cholangiocarcinoma is associated with metastasis and poor prognosis
Cancer Sci
2019
110(10):3197-3203
PubMed ID: 31361379
DOI: 10.1111/cas.14151
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14816
Goyal L, Shi L, Liu LY, Fece de la Cruz F, Lennerz JK, Raghavan S, Leschiner I, Elagina L, Siravegna G, Ng RWS, Vu P, Patra KC, Saha SK, Uppot RN, Arellano R, Reyes S, Sagara T, Otsuki S, Nadres B, Shahzade HA, Dey-Guha I, Fetter IJ, Baiev I, Van Seventer EE, Murphy JE, Ferrone CR, Tanabe KK, Deshpande V, Harding JJ, Yaeger R, Kelley RK, Bardelli A, Iafrate AJ, Hahn WC, Benes CH, Ting DT, Hirai H, Getz G, Juric D, Zhu AX, Corcoran RB, Bardeesy N.
TAS-120 Overcomes Resistance to ATP-Competitive FGFR Inhibitors in Patients with FGFR2 Fusion-Positive Intrahepatic Cholangiocarcinoma
Cancer Discov
2019
9(8):1064-1079
PubMed ID: 31109923
DOI: 10.1158/2159-8290.CD-19-0182
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10740
Merdrignac A, Angenard G, Allain C, Petitjean K, Bergeat D, Bellaud P, Fautrel A, Turlin B, Clément B, Dooley S, Sulpice L, Boudjema K, Coulouarn C.
A novel transforming growth factor beta-induced long noncoding RNA promotes an inflammatory microenvironment in human intrahepatic cholangiocarcinoma.
Hepatol Commun
2018
2:254-269
PubMed ID: 29507901
DOI: 10.1002/hep4.1142
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10770
Mao Y, Huang X, Shuang Z, Lin G, Wang J, Duan F, Chen J, Li S.
PARP inhibitor olaparib sensitizes cholangiocarcinoma cells to radiation.
Cancer Med
2018
7:1285-1296
PubMed ID: 29479816
DOI: 10.1002/cam4.1318
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4487
Shuang Z, Mao Y, Lin G, Wang J, Huang X, Chen J, Duan F, Li S.
Alpha-L-Fucosidase Serves as a Prognostic Indicator for Intrahepatic Cholangiocarcinoma and Inhibits Its Invasion Capacity.
iomed Res Int
2018
2018:8182575
PubMed ID: 29682557
DOI: 10.1155/2018/8182575
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Tan X, Huang Z, Li X.
Long Non-Coding RNA MALAT1 Interacts With miR-204 to Modulate Human Hilar Cholangiocarcinoma Proliferation, Migration, and Invasion by Targeting CXCR4.
J. Cell. Biochem.
2017
118:3643-3653
PubMed ID: 28059437
DOI: 10.1002/jcb.25862
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10501
Kushibiki T, Noji T, Ebihara Y, Hontani K, Ono M, Kuwabara S, Nakamura T, Tsuchikawa T, Okamura K, Ishizuka M, Hirano S.
5-Aminolevulinic-acid-mediated Photodynamic Diagnosis Enhances the Detection of Peritoneal Metastases in Biliary Tract Cancer in Mice.
In Vivo
2017
31:905-908
PubMed ID: 28882957
DOI: 10.21873/invivo.11145
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14252
Maki T, Ikeda H, Kuroda A, Kyogoku N, Yamamura Y, Tabata Y, Abiko T, Tsuchikawa T, Hida Y, Shichinohe T, Tanaka E, Kaga K, Hatanaka K, Matsuno Y, Imai N, Hirano S.
Differential detection of cytoplasmic Wilms tumor 1 expression by immunohistochemistry, western blotting and mRNA quantification
Int J Oncol
2017
50(1):129-140.
PubMed ID: 27922671
DOI: 10.3892/ijo.2016.3786
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14271
Muguruma N, Okamoto K, Nakagawa T, Sannomiya K, Fujimoto S, Mitsui Y, Kimura T, Miyamoto H, Higashijima J, Shimada M, Horino Y, Matsumoto S, Hanaoka K, Nagano T, Shibutani M, Takayama T.
Molecular imaging of aberrant crypt foci in the human colon targeting glutathione S-transferase P1-1
Sci Rep
2017
7(1):6536
PubMed ID: 28747791
DOI: 10.1038/s41598-017-06857-x
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14528
Yagai T, Matsui S, Harada K, Inagaki FF, Saijou E, Miura Y, Nakanuma Y, Miyajima A, Tanaka M.
Expression and localization of sterile alpha motif domain containing 5 is associated with cell type and malignancy of biliary tree
PLoS One
2017
12(4):e0175355
PubMed ID: 28388653
DOI: 10.1371/journal.pone.0175355
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12673
Cavalloni G, Peraldo-Neia C, Varamo C, Casorzo L, Dell'Aglio C, Bernabei P, Chiorino G, Aglietta M, Leone F.
Establishment and characterization of a human intrahepatic cholangiocarcinoma cell line derived from an Italian patient
Tumour Biol
2016
37(3):4041-52
PubMed ID: 26486326
DOI: 10.1007/s13277-015-4215-3
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12878
Yang SH, Lin HY, Changou CA, Chen CH, Liu YR, Wang J, Jiang X, Luh F, Yen Y.
Integrin β3 and LKB1 are independently involved in the inhibition of proliferation by lovastatin in human intrahepatic cholangiocarcinoma
Oncotarget
2016
7(1):362-73
PubMed ID: 26517522
DOI: 10.18632/oncotarget.6238
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14116
Huyen NT, Prachayasittikul V, Chan-On W.
Anoikis-resistant cholangiocarcinoma cells display aggressive characteristics and increase STAT3 activation
J Hepatobiliary Pancreat Sci
2016
23(7):397-405
PubMed ID: 27107220
DOI: 10.1002/jhbp.354
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9170
Sheng-Huei Yang 1, Hung-Yun Lin, Vincent H S Chang, Chien-Chung Chen, Yun-Ru Liu, Jinghan Wang, Keqiang Zhang, Xiaoqing Jiang, Yun Yen
Lovastatin Overcomes Gefitinib Resistance Through TNF-α Signaling in Human Cholangiocarcinomas With Different LKB1 Statuses in Vitro and in Vivo
Oncotarget
2015
6 (27), 23857-73
PubMed ID: 26160843
DOI: 10.18632/oncotarget.4408
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14311
Chan-On W, Huyen NT, Songtawee N, Suwanjang W, Prachayasittikul S, Prachayasittikul V.
Quinoline-based clioquinol and nitroxoline exhibit anticancer activity inducing FoxM1 inhibition in cholangiocarcinoma cells
Drug Des Devel Ther
2015
9:2033-47
PubMed ID: 25897210
DOI: 10.2147/DDDT.S79313
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15203
Wang J, Zhang K, Wang J, Wu X, Liu X, Li B, Zhu Y, Yu Y, Cheng Q, Hu Z, Guo C, Hu S, Mu B, Tsai CH, Li J, Smith L, Yang L, Liu Q, Chu P, Chang V, Zhang B, Wu M, Jiang X, Yen Y.
Underexpression of LKB1 tumor suppressor is associated with enhanced Wnt signaling and malignant characteristics of human intrahepatic cholangiocarcinoma
Oncotarget
2015
6(22):18905-20
PubMed ID: 26056085
DOI: 10.18632/oncotarget.4305
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14930
Takahashi N, Aoyama F, Hiyoshi M, Kataoka H, Sawaguchi A.
Establishment and biological characterization of a novel cell line derived from hepatoid adenocarcinoma originated at the ampulla of Vater
Int J Oncol
2014
44(4):1139-45
PubMed ID: 24481592
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Qiu YH, Wei YP, Shen NJ, Wang ZC, Kan T, Yu WL, Yi B, Zhang YJ.
miR-204 inhibits epithelial to mesenchymal transition by targeting slug in intrahepatic cholangiocarcinoma cells
Cell Physiol Biochem
2013
32(5):1331-41
PubMed ID: 24280681
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Ohashi H, Adachi Y, Yamamoto H, Taniguchi H, Nosho K, Suzuki H, Arimura Y, Imai K, Carbone DP, Shinomura Y.
Insulin-like growth factor receptor expression is associated with aggressive phenotypes and has therapeutic activity in biliary tract cancers.
Cancer Sci
2012
103(2):252-61
PubMed ID: 22044563
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Sugiyama H, Onuki K, Ishige K, Baba N, Ueda T, Matsuda S, Takeuchi K, Onodera M, Nakanuma Y, Yamato M, Yamamoto M, Hyodo I, Shoda J.
Potent in vitro and in vivo antitumor activity of sorafenib against human intrahepatic cholangiocarcinoma cells.
J. Gastroenterol.
2011
46:779-89
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15724
Araki K, Shimura T, Suzuki H, Tsutsumi S, Wada W, Yajima T, Kobayahi T, Kubo N, Kuwano H.
E/N-cadherin switch mediates cancer progression via TGF-β-induced epithelial-to-mesenchymal transition in extrahepatic cholangiocarcinoma
Br J Cancer
2011
105(12):1885-93
PubMed ID: 22068819
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18737
Kawase H, Fujii K, Miyamoto M, Kubota KC, Hirano S, Kondo S, Inagaki F.
Differential LC-MS-based proteomics of surgical human cholangiocarcinoma tissues
J Proteome Res
2009
8(8):4092-103
PubMed ID: 19569727
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