| 利用者成果(英) |
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21415
Fukuoka S, Koga Y, Yamauchi M, Koganemaru S, Yasunaga M, Shitara K, Doi T, Yoshino T, Kuronita T, Elenbaas B, Wahra P, Zhang H, Crowley L, Jenkins MH, Clark A, Kojima T.
p70S6K/Akt dual inhibitor DIACC3010 is efficacious in preclinical models of gastric cancer alone and in combination with trastuzumab.
Sci Rep
2023
13(1):16017
PubMed ID: 37749105
DOI: 10.1038/s41598-023-40612-9
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20999
Takashima H, Ohnuki K, Manabe S, Koga Y, Tsumura R, Anzai T, Wang Y, Yin X, Sato N, Shigekawa Y, Nambu A, Usuda S, Haba H, Fujii H, Yasunaga M.
Tumor Targeting of 211At-Labeled Antibody under Sodium Ascorbate Protection against Radiolysis.
Mol Pharm
2022
PubMed ID: 36573995
DOI: 10.1021/acs.molpharmaceut.2c00869
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20098
Tsuji T, Maeda Y, Kita K, Murakami K, Saya H, Takemura H, Inaki N, Oshima M, Oshima H.
FOXO3 is a latent tumor suppressor for FOXO3-positive and cytoplasmic-type gastric cancer cells.
Oncogene
2021
PubMed ID: 33795838
DOI: 10.1038/s41388-021-01757-x
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20213
Kuramitsu S, Masuda T, Hu Q, Tobo T, Yashiro M, Fujii A, Kitagawa A, Abe T, Otsu H, Ito S, Oki E, Mori M, Mimori K.
Cancer-associated Fibroblast-derived Spondin-2 Promotes Motility of Gastric Cancer Cells.
Cancer Genomics Proteomics
2021
18(4):521-529
PubMed ID: 34183385
DOI: 10.21873/cgp.20277
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16321
Takashima H, Koga Y, Manabe S, Ohnuki K, Tsumura R, Anzai T, Iwata N, Wang Y, Yokokita T, Komori Y, Mori D, Usuda S, Haba H, Fujii H, Matsumura Y, Yasunaga M.
Radioimmunotherapy with an 211 At-labeled anti-tissue factor antibody protected by sodium ascorbate
Cancer Sci
2021
112(5):1975-1986
PubMed ID: 33606344
DOI: 10.1111/cas.14857
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18830
Tang Y, Fang G, Guo F, Zhang H, Chen X, An L, Chen M, Zhou L, Wang W, Ye T, Zhou L, Nie P, Yu H, Lin M, Zhao Y, Lin X, Yuan Z, Jiao S, Zhou Z.
Selective Inhibition of STRN3-Containing PP2A Phosphatase Restores Hippo Tumor-Suppressor Activity in Gastric Cancer
Cancer Cell
2020
:115-128.e9
PubMed ID: 32589942
DOI: 10.1016/j.ccell.2020.05.019
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9737
Tomohiro Kohmoto, Kiyoshi Masuda, Katsutoshi Shoda, Rizu Takahashi, Sae Ujiro, Shoichiro Tange, Daisuke Ichikawa, Eigo Otsuji, Issei Imoto
Claudin-6 Is a Single Prognostic Marker and Functions as a Tumor-Promoting Gene in a Subgroup of Intestinal Type Gastric Cancer
Gastric Cancer
2020
23(3):403-417
PubMed ID: 31654186
DOI: 10.1007/s10120-019-01014-x
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13600
Sano H, Futamura M, Gaowa S, Kamino H, Nakamura Y, Yamaguchi K, Tanaka Y, Yasufuku I, Nakakami A, Arakawa H, Yoshida K.
p53/Mieap-regulated mitochondrial quality control plays an important role as a tumor suppressor in gastric and esophageal cancers
Biochem Biophys Res Commun
2020
529(3):582-589.
PubMed ID: 32736677
DOI: 10.1016/j.bbrc.2020.05.168
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11505
Kageyama-Yahara N, Yamamichi N, Takahashi Y, Takeuchi C, Matsumoto Y, Sakaguchi Y, Koike K.
Tandem repeats of the 5' flanking region of human MUC5AC have a role as a novel enhancer in MUC5AC gene expression.
Biochem Biophys Rep
2019
18:100632
PubMed ID: 30993217
DOI: 10.1016/j.bbrep.2019.100632
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13126
Gaowa S, Futamura M, Tsuneki M, Kamino H, Tajima JY, Mori R, Arakawa H, Yoshida K.
Possible role of p53/Mieap-regulated mitochondrial quality control as a tumor suppressor in human breast cancer.
Cancer Sci
2018
PubMed ID: 30290054
DOI: 10.1111/cas.13824
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10586
Ishii S, Yamashita K, Harada H, Ushiku H, Tanaka T, Nishizawa N, Yokoi K, Washio M, Ema A, Mieno H, Moriya H, Hosoda K, Waraya M, Katoh H, Watanabe M.
The H19-PEG10/IGF2BP3 axis promotes gastric cancer progression in patients with high lymph node ratios.
Oncotarget
2017
8:74567-74581
PubMed ID: 29088808
DOI: 10.18632/oncotarget.20209
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14615
Nambara S, Masuda T, Nishio M, Kuramitsu S, Tobo T, Ogawa Y, Hu Q, Iguchi T, Kuroda Y, Ito S, Eguchi H, Sugimachi K, Saeki H, Oki E, Maehara Y, Suzuki A, Mimori K.
Antitumor effects of the antiparasitic agent ivermectin via inhibition of Yes-associated protein 1 expression in gastric cancer
Oncotarget
2017
8(64):107666-107677
PubMed ID: 29296196
DOI: 10.18632/oncotarget.22587
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5812
Hirashita Y et al
Reduced phosphorylation of ribosomal protein S6 is associated with sensitivity to MEK inhibition in gastric cancer cells.
Cancer Sci
2016
107(12):1919-1928
PubMed ID: 27699948
DOI: 10.1111/cas.13094
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15058
Cheng YJ, Zhu ZX, Zhou JS, Hu ZQ, Zhang JP, Cai QP, Wang LH.
Silencing profilin-1 inhibits gastric cancer progression via integrin β1/focal adhesion kinase pathway modulation
World J Gastroenterol
2015
21(8):2323-35
PubMed ID: 25741138
DOI: 10.3748/wjg.v21.i8.2323
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15159
Honda S, Loher P, Shigematsu M, Palazzo JP, Suzuki R, Imoto I, Rigoutsos I, Kirino Y.
Sex hormone-dependent tRNA halves enhance cell proliferation in breast and prostate cancers
Proc Natl Acad Sci U S A
2015
112(29):E3816-25
PubMed ID: 26124144
DOI: 10.1073/pnas.1510077112
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5845
Konno-Shimizu M1, Yamamichi N, Inada K, Kageyama-Yahara N, Shiogama K, Takahashi Y, Asada-Hirayama I, Yamamichi-Nishina M, Nakayama C, Ono S, Kodashima S, Fujishiro M, Tsutsumi Y, Ichinose M, Koike K.
Cathepsin E is a marker of gastric differentiation and signet-ring cell carcinoma of stomach: a novel suggestion on gastric tumorigenesis.
PLoS One
2013
8(2):e56766
PubMed ID: 23451082
DOI: 10.1371/journal.pone.0056766
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18827
Kubo T, Yanagihara K, Takei Y, Mihara K, Sato Y, Seyama T.
Lipid-conjugated 27-nucleotide double-stranded RNAs with dicer-substrate potency enhance RNAi-mediated gene silencing
Mol Pharm
2012
9(5):1374-83
PubMed ID: 22494497
DOI: 10.1021/mp2006278
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7971
Sato A, Kudo C, Yamakoshi H, Uehara Y, Ohori H, Ishioka C, Iwabuchi Y, Shibata H.
Curcumin analog GO-Y030 is a novel inhibitor of IKKβ that suppresses NF-κB signaling and induces apoptosis.
Cancer Sci.
2011
102:1045-51
PubMed ID: 21272158
DOI: 10.1111/j.1349-7006.2011.01886.x
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5861
Nabeya Y, Suzuki T, Furuya A, Koide N, Ohkoshi M, Takiguchi M, Ochiai T, Matsubara H, Hiwasa T.
Calpain regulates thymidylate synthase-5-fluoro-dUMP complex levels associated with response to 5-fluorouracil in gastric cancer cells.
Cancer Sci.
2011
102(8):1509-15
PubMed ID: 21561529
DOI: 10.1111/j.1349-7006.2011.01978.x
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13715
Kudo C, Yamakoshi H, Sato A, Nanjo H, Ohori H, Ishioka C, Iwabuchi Y, Shibata H.
Synthesis of 86 species of 1,5-diaryl-3-oxo-1,4-pentadienes analogs of curcumin can yield a good lead in vivo
BMC Pharmacol
2011
11:4
PubMed ID: 21619659
DOI: 10.1186/1471-2210-11-4
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6410
Danjoh I, Sone H, Noda N, Iimura E, Nagayoshi M, Saijo K, Hiroyama T, Nakamura Y.
Is parainfluenza virus a threatening virus for human cancer cell lines?
Hum Cell
2009
22(3):81-4
PubMed ID: 19624309
DOI: 10.1111/j.1749-0774.2009.00071.x
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