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21759
Cao Z, Hou Y, Zhao Z, Zhang H, Tian L, Zhang Y, Dong C, Guo F, Tan L, Han Y, Wang W, Jiao S, Tang Y, An L, Zhou Z.
Reactivating Hippo by drug compounds to suppress gastric cancer and enhance chemotherapy sensitivity.
J Biol Chem
2024
300(6):107311
PubMed ID: 38657866
DOI: 10.1016/j.jbc.2024.107311
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17881
Kimura Y, Ohzawa H, Miyato H, Kaneko Y, Kuchimaru T, Takahashi R, Yamaguchi H, Kurashina K, Saito S, Hosoya Y, Lefor AK, Sata N, Kitayama J.
Intraperitoneal transfer of microRNA-29b-containing small extracellular vesicles can suppress peritoneal metastases of gastric cancer
Cancer Sci
2023
Mar 20
PubMed ID: 36939028
DOI: 10.1111/cas.15793
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19708
Hachisu K, Tsuchida A, Takada Y, Mizuno M, Ideo H.
Galectin-4 Is Involved in the Structural Changes of Glycosphingolipid Glycans in Poorly Differentiated Gastric Cancer Cells with High Metastatic Potential
Int J Mol Sci
2023
24(15):12305
PubMed ID: 37569679
DOI: 10.3390/ijms241512305
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19729
Sato T, Saito M, Nakajima S, Saito K, Katagata M, Fukai S, Okayama H, Sakamoto W, Saze Z, Momma T, Mimura K, Kono K.
ARID1A deficiency is targetable by AKT inhibitors in HER2-negative gastric cancer
Gastric Cancer
2023
26(3):379-392
PubMed ID: 36811690
DOI: 10.1007/s10120-023-01373-6
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19939
hiozaki A, Fukami T, Shimizu H, Kosuga T, Kudou M, Takemoto K, Katsurahara K, Nishibeppu K, Ohashi T, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Otsuji E.
Effects of TRPV2 on the Expression of PD-L1 and Its Binding Ability to PD-1 in Gastric Cancer
Ann Surg Oncol
2023
30(13):8704-8716
PubMed ID: 37599296
DOI: 10.1245/s10434-023-14084-0
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21122
Ideo H, Tsuchida A, Takada Y, Kinoshita J, Inaki N, Minamoto T.
Suppression of galectin-4 attenuates peritoneal metastasis of poorly differentiated gastric cancer cells.
Gastric Cancer
2023
PubMed ID: 36695981
DOI: 10.1007/s10120-023-01366-5
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21458
Kitagawa H, Hiraki M, Namba T, Baba K, Miyake S, Ito K, Tanaka T, Noshiro H.
The Oncological Effect of Mutant p53 on the Metastatic Phenotype of Gastric Cancer Cells.
Anticancer Res
2023
43(11):4887-4895
PubMed ID: 37909947
DOI: 10.21873/anticanres.16686
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21486
Lou M, Iwatsuki M, Wu X, Zhang W, Matsumoto C, Baba H.
Cancer-Associated Fibroblast-Derived IL-8 Upregulates PD-L1 Expression in Gastric Cancer Through the NF-κB Pathway.
Ann Surg Oncol
2023
PubMed ID: 38006530
DOI: 10.1245/s10434-023-14586-x
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17567
Takashima Y, Komatsu S, Ohashi T, Kiuchi J, Kamiya H, Shimizu H, Arita T, Konishi H, Shiozaki A, Kubota T, Okamoto K, Fujiwara H, Tsuda H, Otsuji E.
Overexpression of Tetraspanin31 contributes to malignant potential and poor outcomes in gastric cancer
Cancer Sci
2022
113(6):1984-1998
PubMed ID: 35307915
DOI: 10.1111/cas.15342
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17646
Ogawa K, Yamada K, Etoh T, Kitagawa M, Shirasaka Y, Noguchi K, Kobayashi T, Nishizono A, Inomata M.
Development of an oncolytic mammalian orthoreovirus expressing the near-infrared fluorescent protein iRFP720
J Virol Methods
2022
308:114574
PubMed ID: 35798198
DOI: 10.1016/j.jviromet.2022.114574
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20459
Kato S, Shiozaki A, Kudou M, Shimizu H, Kosuga T, Ohashi T, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, Otsuji E.
TRPV2 Promotes Cell Migration and Invasion in Gastric Cancer via the Transforming Growth Factor-β Signaling Pathway.
Ann Surg Oncol
2022
PubMed ID: 34855064
DOI: 10.1245/s10434-021-11132-5
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20609
Shen Y, Eng JS, Fajardo F, Liang L, Li C, Collins P, Tedesco D, Nolan-Stevaux O.
Cancer cell-intrinsic resistance to BiTE therapy is mediated by loss of CD58 costimulation and modulation of the extrinsic apoptotic pathway.
J Immunother Cancer
2022
10(3)
PubMed ID: 35296559
DOI: 10.1136/jitc-2021-004348
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20622
Takaki W, Konishi H, Matsubara D, Shoda K, Arita T, Kataoka S, Shibamoto J, Furuke H, Takabatake K, Shimizu H, Komatsu S, Shiozaki A, Kubota T, Okamoto K, Otsuji E.
Role of Extracellular High-Mobility Group Box-1 as a Therapeutic Target of Gastric Cancer.
Int J Mol Sci
2022
23(6)
PubMed ID: 35328684
DOI: 10.3390/ijms23063264
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20627
Soda T, Gen Y, Terasaki K, Iwai N, Kitaichi T, Dohi O, Taketani H, Seko Y, Umemura A, Nishikawa T, Yamaguchi K, Moriguchi M, Konishi H, Naito Y, Itoh Y, Yasui K.
Loss of KAP3 decreases intercellular adhesion and impairs intracellular transport of laminin in signet ring cell carcinoma of the stomach.
Sci Rep
2022
12(1):5050
PubMed ID: 35322078
DOI: 10.1038/s41598-022-08904-8
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20661
Inoue H, Shiozaki A, Kosuga T, Shimizu H, Kudou M, Ohashi T, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, Otsuji E.
Functions and Clinical Significance of CACNA2D1 in Gastric Cancer.
Ann Surg Oncol
2022
PubMed ID: 35445337
DOI: 10.1245/s10434-022-11752-5
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16894
Kimura Y, Ohzawa H, Miyato H, Kaneko Y, Saito A, Takahashi K, Tojo M, Yamaguchi H, Kurashina K, Saito S, Hosoya Y, Lefor AK, Sata N, Kitayama J.
MiR-29b may suppresses peritoneal metastases through inhibition of the mesothelial-mesenchymal transition (MMT) of human peritoneal mesothelial cells
Sci Rep
2022
12(1):205
PubMed ID: 34997082
DOI: 10.1038/s41598-021-04065-2
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16979
Ma J, Zhang C, Liang W, Li L, Du J, Pan C, Chen B, Chen Y, Wang Y.
ω-3 and ω-6 Polyunsaturated Fatty Acids Regulate the Proliferation, Invasion and Angiogenesis of Gastric Cancer Through COX/PGE Signaling Pathway
Front Oncol
2022
12:802009
PubMed ID: 35251974
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21996
Fukami T, Shiozaki A, Kosuga T, Kudou M, Shimizu H, Ohashi T, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Morinaga Y, Konishi E, Otsuji E.
Anoctamin 5 regulates the cell cycle and affects prognosis in gastric cancer
World J Gastroenterol
2022
28(32):4649-4667.
PubMed ID: 36157935
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18099
Kato T, Nakamori M, Matsumura S, Nakamura M, Ojima T, Fukuhara H, Ino Y, Todo T, Yamaue H.
Oncolytic virotherapy with human telomerase reverse transcriptase promoter regulation enhances cytotoxic effects against gastric cancer
Oncol Lett
2021
21(6):490
PubMed ID: 33968206
DOI: 10.3892/ol.2021.12751
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13160
Sakuratani T, Takeuchi T, Yasufuku I, Iwata Y, Saigo C, Kito Y, Yoshida K.
Downregulation of ARID1A in gastric cancer cells: a putative protective molecular mechanism against the Harakiri-mediated apoptosis pathway.
Virchows Arch
2021
478(3):401-411
PubMed ID: 32789692
DOI: 10.1007/s00428-020-02899-1
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13323
Nishibeppu K, Komatsu S, Kiuchi J, Kishimoto T, Takashima Y, Shoda K, Arita T, Kosuga T, Konishi H, Shiozaki A, Kubota T, Okamoto K, Fujiwara H, Tsuda H, Otsuji E.
TRIM37 contributes to malignant outcomes and CDDP resistance in gastric cancer.
J Cancer
2021
PubMed ID: 33391428
DOI: 10.7150/jca.47577
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13337
Kim S, Ahn JM, Bae WJ, Han JH, Lee D.
Quantitation of ligand is critical for ligand-dependent MET signalling activation and determines MET-targeted therapeutic response in gastric cancer.
Gastric Cancer
2021
24(3):577-588
PubMed ID: 33164142
DOI: 10.1007/s10120-020-01139-4
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20116
Kurashima K, Shiozaki A, Kudou M, Shimizu H, Arita T, Kosuga T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, Otsuji E.
LRRC8A influences the growth of gastric cancer cells via the p53 signaling pathway.
Gastric Cancer
2021
PubMed ID: 33864161
DOI: 10.1007/s10120-021-01187-4
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20135
Saitoh Y, Kawasaki N, Eguchi N, Ikeshima M.
Combined treatment with dissolved hydrogen molecule and platinum nanocolloid exerts carcinostatic/carcinocidal effects by increasing hydrogen peroxide generation and cell death in the human gastric cancer cell line NUGC-4.
Free Radic Res
2021
1-10
PubMed ID: 33929281
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20148
Kubo H, Murayama Y, Ogawa S, Matsumoto T, Yubakami M, Ohashi T, Kubota T, Okamoto K, Kamiya M, Urano Y, Otsuji E.
β-Galactosidase is a target enzyme for detecting peritoneal metastasis of gastric cancer.
Sci Rep
2021
11(1):10664
PubMed ID: 34021168
DOI: 10.1038/s41598-021-88982-2
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14345
Katsurahara K, Shiozaki A, Kosuga T, Shimizu H, Kudou M, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, Otsuji E.
ANO9 regulates PD-L2 expression and binding ability to PD-1 in gastric cancer
Cancer Sci
2021
112(3):1026-1037.
PubMed ID: 33404124
DOI: 10.1111/cas.14796
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20213
Kuramitsu S, Masuda T, Hu Q, Tobo T, Yashiro M, Fujii A, Kitagawa A, Abe T, Otsu H, Ito S, Oki E, Mori M, Mimori K.
Cancer-associated Fibroblast-derived Spondin-2 Promotes Motility of Gastric Cancer Cells.
Cancer Genomics Proteomics
2021
18(4):521-529
PubMed ID: 34183385
DOI: 10.21873/cgp.20277
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20224
Ogawa S, Kubo H, Murayama Y, Kubota T, Yubakami M, Matsumoto T, Ohashi T, Okamoto K, Kuriki Y, Hanaoka K, Urano Y, Otsuji E.
Matrix metalloprotease-14 is a Target Enzyme for Detecting Peritoneal Metastasis in Gastric Cancer.
Photodiagnosis Photodyn Ther
2021
PubMed ID: 34242818
DOI: 10.1016/j.pdpdt.2021.102420
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20286
Zhang X, Yamamoto Y, Wang X, Sato M, Imanishi M, Sugaya A, Hirose M, Endo S, Moriwaki T, Yamato K, Hyodo I.
MDM4 as a Prognostic Factor for Patients With Gastric Cancer With Low Expression of p53.
Anticancer Res
2021
41(3):1475-1483
PubMed ID: 33788740
DOI: 10.21873/anticanres.14906
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20520
Komatsu S, Imamura T, Kiuchi J, Takashima Y, Kamiya H, Ohashi T, Konishi H, Shiozaki A, Kubota T, Okamoto K, Otsuji E.
Depletion of tumor suppressor miRNA-148a in plasma relates to tumor progression and poor outcomes in gastric cancer.
Am J Cancer Res
2021
11(12):6133-6146
PubMed ID: 35018247
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16126
Nakamura K, Shiozaki A, Kosuga T, Shimizu H, Kudou M, Ohashi T, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, Otsuji E.
The expression of the alpha1 subunit of Na +/K +-ATPase is related to tumor development and clinical outcomes in gastric cancer
Gastric Cancer
2021
24(6):1278-1292
PubMed ID: 34251542
DOI: 10.1007/s10120-021-01212-6
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16866
Yamashita K, Iwatsuki M, Yasuda-Yoshihara N, Morinaga T, Nakao Y, Harada K, Eto K, Kurashige J, Hiyoshi Y, Ishimoto T, Nagai Y, Iwagami S, Baba Y, Miyamoto Y, Yoshida N, Ajani JA, Baba H.
Trastuzumab upregulates programmed death ligand-1 expression through interaction with NK cells in gastric cancer
Br J Cancer
2021
124(3):595-603
PubMed ID: 33100329
DOI: 10.1038/s41416-020-01138-3
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14297
Kumagai Y, Ohzawa H, Miyato H, Horie H, Hosoya Y, Lefor AK, Sata N, Kitayama J.
Surgical Stress Increases Circulating Low-Density Neutrophils Which May Promote Tumor Recurrence
J Surg Res
2020
246:52-61
PubMed ID: 31561178
DOI: 10.1016/j.jss.2019.08.022
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19269
Shun Zhang, Yoshinori Kohira, Hajime Orita, Momoko Ishimine, Toshiyuki Kobayashi, Sharlyn Mae Buendia Chua, Hirofumi Nakaoka, Ituro Inoue, Okio Hino, Takehiko Yokomizo, Tetsu Fukunaga, Hyeon-Cheol Lee-Okada
Sensitization of Gastric Cancer Cells to Irinotecan by p53 Activation
BPB Reports
2019
2:130-133
DOI: 10.1248/bpbreports.2.6_130
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11202
Shiozaki A, Ariyoshi Y, Iitaka D, Kosuga T, Shimizu H, Kudou M, Konishi T, Shoda K, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, Marunaka Y, Ichikawa D, Otsuji E.
Functional analysis and clinical significance of sodium iodide symporter expression in gastric cancer.
Gastric Cancer
2019
PubMed ID: 30191346
DOI: 10.1007/s10120-018-0874-2
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11733
Shiozaki A, Yamazato Y, Kosuga T, Kudou M, Shoda K, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Marunaka Y, Otsuji E.
Effect of low temperature on the regulation of cell volume after hypotonic shock in gastric cancer cells.
Int. J. Oncol.
2019
PubMed ID: 31432150
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11969
Desamero MJ, Kakuta S, Tang Y, Chambers JK, Uchida K, Estacio MA, Cervancia C, Kominami Y, Ushio H, Nakayama J, Nakayama H, Kyuwa S.
Tumor-suppressing potential of stingless bee propolis in in vitro and in vivo models of differentiated-type gastric adenocarcinoma.
Sci Rep
2019
PubMed ID: 31873082
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Sensitization of Gastric Cancer Cells to Irinotecan by p53 Activation
BPB Reports
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Imanishi M, Yamamoto Y, Wang X, Sugaya A, Hirose M, Endo S, Natori Y, Yamato K, Hyodo I.
Augmented antitumor activity of 5-fluorouracil by double knockdown of MDM4 and MDM2 in colon and gastric cancer cells
Cancer Sci
2019
110(2):639-649
PubMed ID: 30488540
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11246
Kimura R, Yoneshige A, Hagiyama M, Otani T, Inoue T, Shiraishi N, Yanagihara K, Wakayama T, Ito A.
Expression of cell adhesion molecule 1 in gastric neck and base glandular cells: Possible involvement in peritoneal dissemination of signet ring cells.
Life Sci.
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Kurata A, Yamada M, Ohno SI, Inoue S, Hashimoto H, Fujita K, Takanashi M, Kuroda M.
Expression level of microRNA-200c is associated with cell morphology in vitro and histological differentiation through regulation of ZEB1/2 and E-cadherin in gastric carcinoma.
Oncol. Rep.
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PubMed ID: 29138864
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Kiuchi J, Komatsu S, Imamura T, Nishibeppu K, Shoda K, Arita T, Kosuga T, Konishi H, Shiozaki A, Kubota T, Okamoto K, Fujiwara H, Ichikawa D, Tsuda H, Otsuji E.
Overexpression of YEATS4 contributes to malignant outcomes in gastric carcinoma.
Am J Cancer Res
2018
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Kanamaru R, Ohzawa H, Miyato H, Yamaguchi H, Hosoya Y, Lefor AK, Sata N, Kitayama J.
Neutrophil Extracellular Traps Generated by Low Density Neutrophils Obtained from Peritoneal Lavage Fluid Mediate Tumor Cell Growth and Attachment
J Vis Exp
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Imamura T, Komatsu S, Ichikawa D, Miyamae M, Okajima W, Ohashi T, Kiuchi J, Nishibeppu K, Kosuga T, Konishi H, Shiozaki A, Fujiwara H, Okamoto K, Tsuda H, Otsuji E.
Overexpression of ZRF1 is related to tumor malignant potential and a poor outcome of gastric carcinoma
Carcinogenesis
2018
39(2):263-271
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Jia L, Ren S, Li T, Wu J, Zhou X, Zhang Y, Wu J, Liu W.
Effects of Combined Simultaneous and Sequential Endostar and Cisplatin Treatment in a Mice Model of Gastric Cancer Peritoneal Metastases.
Gastroenterol Res Pract
2017
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Gen Y, Yasui K, Kitaichi T, Iwai N, Terasaki K, Dohi O, Hashimoto H, Fukui H, Inada Y, Fukui A, Jo M, Moriguchi M, Nishikawa T, Umemura A, Yamaguchi K, Konishi H, Naito Y, Itoh Y.
ASPP2 suppresses invasion and TGF-β1-induced epithelial-mesenchymal transition by inhibiting Smad7 degradation mediated by E3 ubiquitin ligase ITCH in gastric cancer.
Cancer Lett.
2017
398:52-61
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10586
Ishii S, Yamashita K, Harada H, Ushiku H, Tanaka T, Nishizawa N, Yokoi K, Washio M, Ema A, Mieno H, Moriya H, Hosoda K, Waraya M, Katoh H, Watanabe M.
The H19-PEG10/IGF2BP3 axis promotes gastric cancer progression in patients with high lymph node ratios.
Oncotarget
2017
8:74567-74581
PubMed ID: 29088808
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10686
Imamura T, Komatsu S, Ichikawa D, Miyamae M, Okajima W, Ohashi T, Kiuchi J, Nishibeppu K, Kosuga T, Konishi H, Shiozaki A, Okamoto K, Fujiwara H, Otsuji E.
Low plasma levels of miR-101 are associated with tumor progression in gastric cancer.
Oncotarget
2017
8:106538-106550
PubMed ID: 29290969
DOI: 10.18632/oncotarget.20860
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5804
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Molecular heterogeneity in the novel fusion gene APIP-FGFR2: Diversity of genomic breakpoints in gastric cancer with high-level amplifications at 11p13 and 10q26
Oncology Letters
2017
13(1):215-221
PubMed ID: 28123544
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9931
Man Hagiyama, Norikazu Yabuta, Daisuke Okuzaki, Takao Inoue, Yasutoshi Takashima, Ryuichiro Kimura, Aritoshi Ri, Akihiko Ito
Modest Static Pressure Suppresses Columnar Epithelial Cell Growth in Association With Cell Shape and Cytoskeletal Modifications
Front Physiol
2017
8:997
PubMed ID: 29259558
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14271
Muguruma N, Okamoto K, Nakagawa T, Sannomiya K, Fujimoto S, Mitsui Y, Kimura T, Miyamoto H, Higashijima J, Shimada M, Horino Y, Matsumoto S, Hanaoka K, Nagano T, Shibutani M, Takayama T.
Molecular imaging of aberrant crypt foci in the human colon targeting glutathione S-transferase P1-1
Sci Rep
2017
7(1):6536
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14615
Nambara S, Masuda T, Nishio M, Kuramitsu S, Tobo T, Ogawa Y, Hu Q, Iguchi T, Kuroda Y, Ito S, Eguchi H, Sugimachi K, Saeki H, Oki E, Maehara Y, Suzuki A, Mimori K.
Antitumor effects of the antiparasitic agent ivermectin via inhibition of Yes-associated protein 1 expression in gastric cancer
Oncotarget
2017
8(64):107666-107677
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14738
Wei H, Cai H, Jin Y, Wang P, Zhang Q, Lin Y, Wang W, Cheng J, Zeng N, Xu T, Zhou A.
Structural basis of a novel heterodimeric Fc for bispecific antibody production
Oncotarget
2017
8(31):51037-51049
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14744
Ohashi T, Komatsu S, Ichikawa D, Miyamae M, Okajima W, Imamura T, Kiuchi J, Kosuga T, Konishi H, Shiozaki A, Fujiwara H, Okamoto K, Tsuda H, Otsuji E.
Overexpression of PBK/TOPK relates to tumour malignant potential and poor outcome of gastric carcinoma
Br J Cancer
2017
116(2):218-226
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Bioequivalence Studies of A Generic Formulation (SW651K) to the Brand Drug S-1 in Tumor-Bearing Rat Models
Journal of Bioequivalence & Bioavailability
2016
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RNAi-mediated gene silencing of ST6GalNAc I suppresses the metastatic potential in gastric cancer cells.
Gastric Cancer
2016
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Nakamura S, Kahyo T, Tao H, Shibata K, Kurabe N, Yamada H, Shinmura K, Ohnishi K, Sugimura H.
Novel roles for LIX1L in promoting cancer cell proliferation through ROS1-mediated LIX1L phosphorylation.
Sci Rep
2015
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Toiyama Y, Tanaka K, Kitajima T, Shimura T, Imaoka H, Mori K, Okigami M, Yasuda H, Okugawa Y, Saigusa S, Ohi M, Inoue Y, Mohri Y, Goel A, Kusunoki M.
Serum angiopoietin-like protein 2 as a potential biomarker for diagnosis, early recurrence and prognosis in gastric cancer patients
Carcinogenesis
2015
36(12):1474-83
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Honda S, Loher P, Shigematsu M, Palazzo JP, Suzuki R, Imoto I, Rigoutsos I, Kirino Y.
Sex hormone-dependent tRNA halves enhance cell proliferation in breast and prostate cancers
Proc Natl Acad Sci U S A
2015
112(29):E3816-25
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Waraya M, Yamashita K, Ema A, Katada N, Kikuchi S, Watanabe M.
Exclusive Association of p53 Mutation with Super-High Methylation of Tumor Suppressor Genes in the p53 Pathway in a Unique Gastric Cancer Phenotype
PLoS One
2015
10(10):e0139902
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Ito T, Kajino K, Abe M, Sato K, Maekawa H, Sakurada M, Orita H, Wada R, Kajiyama Y, Hino O.
ERC/mesothelin is expressed in human gastric cancer tissues and cell lines.
Oncol Rep
2014
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Antitumor effects of a sirtuin inhibitor, tenovin-6, against gastric cancer cells via death receptor 5 up-regulation.
PLoS One
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9(7):e102831
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Sato M, Muguruma N, Nakagawa T, Okamoto K, Kimura T, Kitamura S, Yano H, Sannomiya K, Goji T, Miyamoto H, Okahisa T, Mikasa H, Wada S, Iwata M, Takayama T.
High antitumor activity of pladienolide B and its derivative in gastric cancer.
Cancer Sci
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