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細胞番号 : 細胞名
RCB1904 : MCF7  update : 2022/06/27
細胞特性(Comment:英)Human cell line derived from breast adenocarcinoma. TKG0479 (Deposited from Tohoku Univ.).
細胞特性(日)ヒト乳腺癌由来細胞株。 TKG0479 (東北大学医用細胞資源センターからの寄託)。
使用条件(英)There is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC.
提供申込書類(英) Order Form(C-0005.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)  
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
提供申込書類(日) 依頼書C-0001.pdf   同意書(非営利学術目的)C-0003.pdf   同意書(営利目的)C-0003p.pdf  
提供同意書は、使用機関の種類や目的に応じて、非営利学術目的 (C-XXXX) と営利目的 (C-XXXXp) の2種類があります。該当する提供同意書をご使用ください(詳細)。特許等の取得及び商業利用等は事前に必ず cellbank.brc@riken.jp までご連絡ください。
提供手数料 手数料とお支払いについてはこちらをご覧ください。
細胞基本情報 寄託者 Obinata, Masuo
樹立者 Soule H.D.
寄託日 2004
元の細胞 TKG0479
動物種 human < Mammals
属名 Homo
種名 sapiens
人種 Caucasian
性別 Female
69 years
採取組織 brest, pleural fluid
病名 breast adenocarcunima
細胞分類 cancer
入手歴 Cell Resource Center for Biomedical Research, Tohoku University(TKG0479)
メモ_1 A culture submitted to the CRCBR, Tohoku University was found to be contaminated with mycoplasma. Mycoplasma was eliminated with BM Cycline and MC210 at the CRCBR.
細胞寿命 infinite
細胞形態 epithelial-like
Cellosaurus(Expasy) CVCL_0031
培地・試薬情報 培地・試薬一覧はこちらをご覧ください。
培養形態 Adherent cells
培地 MEM + 10% FBS + 1mM Sodium Pyruvate + 0.1mM NEAA
抗生物質 Free
継代方法 0.25% Trypsin
継代密度 1 : 8 split
継代・培地交換頻度 Subculture : once/week, Medium Renewal : 2 times/week
培養最適温度 37 ℃
二酸化炭素濃度 5 %
凍結培地 Medium + 10% DMSO
凍結方法 Slow freezing
マイコプラズマ (-)
アイソザイム検査 LD, NP, AST
個体識別検査 OK
文献情報 Reference(英) 5件
Reference(日) 1件
利用者成果(英) 184件
利用者成果(日) 0件

4765  Yang NS, Soule HD, McGrath CM.  Expression of murine mammary tumor virus-related antigens in human breast carcinoma (MCF-7) cells.  J Natl Cancer Inst  1977  59(5):1357-67  PubMed ID: 71356
4764  Russo J, Soule HD, McGrath C, Rich MA.  Reexpression of the original tumor pattern by a human breast carcinoma cell line (MCF-7) in sponge culture.  J Natl Cancer Inst  1976  56(2):279-82  PubMed ID: 176383
4763  McGrath CM, Grant PM, Soule HD, Glancy T, Rich MA.  Replication of oncornavirus-like particle in human breast carcinoma cell line, MCF-7.  Nature  1974  252(5480):247-50  PubMed ID: 4138511
4761  Soule HD, Vazguez J, Long A, Albert S, Brennan M.  A human cell line from a pleural effusion derived from a breast carcinoma.  J Natl Cancer Inst  1973  51(5):1409-16  PubMed ID: 4357757
4762  Brooks SC, Locke ER, Soule HD.  Estrogen receptor in a human cell line (MCF-7) from breast carcinoma.  J Biol Chem  1973  248(17):6251-3  PubMed ID: 4353636

1704  堀内龍也  ヒト乳癌 : MCF-7  生体の科学  1992  43:363-364 

14519  Kudo M, Anam MB, Istiaq A, Ahmad SAI, Ito N, Ohta K.  Ribosome Incorporation Induces EMT-like Phenomenon with Cell Cycle Arrest in Human Breast Cancer Cell  Cells Tissues Organs  2022  1-10  PubMed ID: 33640894
15439  Shams R, Matsukawa A, Ochi Y, Ito Y, Miyatake H.  In Silico and In Cell Hybrid Selection of Nonrapalog Ligands to Allosterically Inhibit the Kinase Activity of mTORC1  J Med Chem  2022  Jun 30  PubMed ID: 34191518
15952  Kawahara R, Simizu S.  ErbB4-mediated regulation of vasculogenic mimicry capability in breast cancer cells  Cancer Sci   2022  2021 Dec 31  PubMed ID: 34971015
20613  Shimmyo N, Furuhata M, Yamada M, Utoh R, Seki M.  Process simplification and structure design of parallelized microslit isolator for physical property-based capture of tumor cells.  Analyst  2022    PubMed ID: 35297918
16497  Toshie Tanaka, Kohei Sano, Mamia Munemura, Masayori Hagimori, Rioh Moriyama, Azusa Yamamoto, Kei-ichi Ozaki, Masayuki Munekane, Toshihide Yamasaki, Takahiro Mukai  A radiolabeled nanoparticle probe coated with hyaluronic acid via electrostatic interaction to diagnose CD44-positive tumors  Journal of Drug Delivery Science and Technology  2022  103473 
20752  Shindo S, Shioya A, Watanabe M, Sasaki T, Suzuki H, Kumagai T, Hwang GW, Nagata K.  Development of an adenovirus-mediated reporter assay system to detect a low concentration of retinoic acid in MCF-7 cells.  J Toxicol Sci  2022  47(6):249-255  PubMed ID: 35650141
16737  Yusuke Takizawa, Junya Oguri, Masaya Uno, Ami Onsui, Atsushi Ishimura, Takuro Kurita, Takanori Nakajima  Effects of A GLP‑1 Receptor Agonist on Gastrointestinal Epithelial Cells  Scholars Academic Journal of Pharmacy  2022  11:60-66 
16741  Isaac Kingsley Amponsah, Gina Flor Ramos, Benjamin Kingsley Harley, Joseph Adusei Sarkodie, Edmund Ekuadzi, Elikplim Kwesi Ampofo, Inemesit Okon Ben  Anti-inflammatory, Antioxidant and Cytotoxic Activities of Guibourtia ehie on Human Prostate (PC-3) and Breast Cancer (MC-7) Cell Lines and in silico Studies on Its Metabolite 7,4′-Dihydroxyflavone  Chemistry Africa  2022  5:627-639 
20799  Fujimoto M, Takii R, Matsumoto M, Okada M, Nakayama KI, Nakato R, Fujiki K, Shirahige K, Nakai A.  HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.  Nat Commun  2022  13(1):4355  PubMed ID: 35906200
12852  Kawai T, Mihara Y, Morita M, Ohkubo M, Asami T, Watanabe TM.  Quantitation of Cell Membrane Permeability of Cyclic Peptides by Single-Cell Cytoplasm Mass Spectrometry  Anal Chem  2021    PubMed ID: 33550808
13361  Luo F, Sugita H, Muraki K, Saeki S, Chaipech S, Pongpiriyadacha Y, Muraoka O, Morikawa T.  Anti-proliferative activities of coumarins from the Thai medicinal plant Mammea siamensis (Miq.) T. Anders. against human digestive tract carcinoma cell lines.  Fitoterapia  2021    PubMed ID: 33246033
13416  Sagara M, Miyamoto S, Itoh S, Soda Y, Tani K.  Development of New Oncolytic Virotherapy Targeting Breast Cancer Using Coxsackievirus B3.  Anticancer Res  2021    PubMed ID: 33419801
20159  Sakabe T, Wakahara M, Shiota G, Umekita Y.  Role of cytoplasmic localization of maspin in promoting cell invasion in breast cancer with aggressive phenotype.  Sci Rep  2021  11(1):11321  PubMed ID: 34059749
15503  Takeo Takeda, Masahiro Ogawa, Junya Kitamoto, Takahiro Kyoya, Megumi Terada  High Glucose Enhances Skin Sensitizer-induced NRF2 Activation In Vitro  The Open Toxicology Journal  2021  7:8-17 
15518  Kawasaki Y, Sendo T.  Three photoinitiators induce breast tumor growth in mouse xenografts with MCF-7 breast cancer cells  Curr Res Toxicol  2021  2:322-328  PubMed ID: 34522900
20360  Kashio-Yokota Y, Sato S, Hirose T, Watanabe T, Endo A, Watanabe F, Endo M, Ohba K, Mori T, Takahashi K.  Elevated (Pro)renin Receptor Expression by Anti-Cancer Drugs, Carboplatin and Paclitaxel, in Cultured Cancer Cells: Possible Involvement of Apoptosis and Autophagy.  Tohoku J Exp Med  2021  255(2):91-104  PubMed ID: 34645770
20379  Imashiro C, Takeshita H, Morikura T, Miyata S, Takemura K, Komotori J.  Development of accurate temperature regulation culture system with metallic culture vessel demonstrates different thermal cytotoxicity in cancer and normal cells.  Sci Rep  2021  11(1):21466  PubMed ID: 34728686
20392  Shikata M, Toyooka T, Komaki Y, Ibuki Y.  4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone-Induced Histone Acetylation via α7nAChR-Mediated PI3K/Akt Activation and Its Impact on γ-H2AX Generation.  Chem Res Toxicol  2021    PubMed ID: 34784199
20401  Oda Y, Takahashi C, Harada S, Nakamura S, Sun D, Kiso K, Urata Y, Miyachi H, Fujiyoshi Y, Honigmann A, Uchida S, Ishihama Y, Toyoshima F.  Discovery of anti-inflammatory physiological peptides that promote tissue repair by reinforcing epithelial barrier formation.  Sci Adv  2021  7(47):eabj6895  PubMed ID: 34788088
20406  Sawa C, Yofu S, Kiriyama K, Sutoh K, Saito T, Kishi S, Gunji M, Inoue Y, Sugi M, Shioda S, Honda K.  High concentration of extracellular nucleotides suppresses cell growth via delayed cell cycle progression in cancer and noncancer cell lines.  Heliyon  2021  7(11):e08318  PubMed ID: 34816032
20434  Chia JY, Miki T, Mihara H, Tsutsumi H.  Biofunctional supramolecular hydrogels fabricated from a short self-assembling peptide modified with bioactive sequences for the 3D culture of breast cancer MCF-7 cells.  Bioorg Med Chem  2021  46:116345  PubMed ID: 34416510
16102  Arung ET, Ramadhan R, Khairunnisa B, Amen Y, Matsumoto M, Nagata M, Kusuma IW, Paramita S, Sukemi, Yadi, Tandirogang N, Takemoto N, Syafrizal, Kim YU, Shimizu K.  Cytotoxicity effect of honey, bee pollen, and propolis from seven stingless bees in some cancer cell lines  Saudi J Biol Sci  2021  ;28(12):7182-7189  PubMed ID: 34867021
16111  Ii H, Nohara Y, Yoshiya T, Masuda S, Tsuda S, Oishi S, Friedman J, Kawabe T, Nakata S.  Identification of U83836E as a γ-glutamylcyclotransferase inhibitor that suppresses MCF7 breast cancer xenograft growth  Biochem Biophys Res Commun  2021  549:128-134  PubMed ID: 33676180
16372  Yoshitaka Koseki, Yoshikazu Ikuta, Farsai Taemaitree, Nozomi Saito, Ryuju Suzuki, Anh Thi Ngoc Dao, Tsunenobu Onodera, Hidetoshi Oikawa, Hitoshi Kasai  Fabrication of size-controlled SN-38 pure drug nanocrystals through an ultrasound-assisted reprecipitation method toward efficient drug delivery for cancer treatment  Journal of Crystal Growth  2021  572:126265 
16522  Kawatani M, Aono H, Hiranuma S, Shimizu T, Muroi M, Ogawa N, Ohishi T, Ohba SI, Kawada M, Nogawa T, Okano A, Hashizume D, Osada H.  Identification of a Small-Molecule Glucose Transporter Inhibitor, Glutipyran, That Inhibits Cancer Cell Growth  ACS Chem Biol  2021  16(8):1576-1586  PubMed ID: 34296611
16701  Chinen T, Yamazaki K, Hashimoto K, Fujii K, Watanabe K, Takeda Y, Yamamoto S, Nozaki Y, Tsuchiya Y, Takao D, Kitagawa D.  Centriole and PCM cooperatively recruit CEP192 to spindle poles to promote bipolar spindle assembly  J Cell Biol  2021  220(2):e202006085  PubMed ID: 33443571
16728  YUSUF LIMBONGAN, RICO RAMADHAN, KUNIYOSHI SHIMIZU, Enos Tangkearung  Agronomic characteristics of 30 promising lines of aromatic, red, and black rice and their antioxidant and cytotoxic effects in some cancer cells  Biodiversitas Journal of Biological Diversity  2021   
16735  Okada H, Mimura M, Tomita S, Kurita R.  Affinity Diversification of a Polymer Probe for Pattern-recognition-based Biosensing Using Chemical Additives  Anal Sci   2021  37(5):713-719  PubMed ID: 33518589
6048  Nashimoto Y, Okada R, Hanada S, Arima Y, Nishiyama K, Miura T, Yokokawa R.  Vascularized cancer on a chip: The effect of perfusion on growth and drug delivery of tumor spheroid.  Biomaterials  2020  229:119547  PubMed ID: 31710953
6885  Asano M, Tanaka S, Sakaguchi M.  Effects of normothermic microwave irradiation on CD44+/CD24‒ in breast cancer MDA-MB-231 and MCF-7 cell lines.  Biosci Biotechnol Biochem.  2020  84(1):103-110  PubMed ID: 31559912
6905  Toda H, Seki N, Kurozumi S, Shinden Y, Yamada Y, Nohata N, Moriya S, Idichi T, Maemura K, Fujii T, Horiguchi J, Kijima Y, Natsugoe S.  RNA-sequence-based microRNA expression signature in breast cancer: tumor-suppressive miR-101-5p regulates molecular pathogenesis.  Mol Oncol  2020  14(2):426-446  PubMed ID: 31755218
6932  Yeong KY, Khaw KY, Takahashi Y, Itoh Y, Murugaiyah V, Suzuki T.  Discovery of gamma-mangostin from Garcinia mangostana as a potent and selective natural SIRT2 inhibitor.  Bioorg Chem  2020  94:103403  PubMed ID: 31711765
10147  Mohamed O Radwan, Halil I Ciftci, Taha F S Ali, Ryoko Koga, Hiroshi Tateishi, Akiko Nakata, Akihiro Ito, Minoru Yoshida, Mikako Fujita, Masami Otsuka  Structure activity study of S-trityl-cysteamine dimethylaminopyridine derivatives as SIRT2 inhibitors: Improvement of SIRT2 binding and inhibition  Bioorg Med Chem Lett  2020  30(19):127458  PubMed ID: 32755678
11920  Takumi Chinen , Shohei Yamamoto, Yutaka Takeda , Koki Watanabe, Kanako Kuroki , Kaho Hashimoto , Daisuke Takao , Daiju Kitagawa  NuMA assemblies organize microtubule asters to establish spindle bipolarity in acentrosomal human cells  EMBO J  2020    PubMed ID: 31782546
12004  Borah A, Pillai SC, Rochani AK, Palaninathan V, Nakajima Y, Maekawa T, Kumar DS.  GANT61 and curcumin-loaded PLGA nanoparticles for GLI1 and PI3K/Akt-mediated inhibition in breast adenocarcinoma.  Nanotechnology  2020    PubMed ID: 31952056
12047  Dadzie I, Avorgbedo SA, Appiah-Opong R, Cudjoe O.  Cytotoxic and Antioxidant Effects of Antimalarial Herbal Mixtures.  Int J Microbiol  2020    PubMed ID: 32104181
12054  Takeda K, Kawamoto Y, Nagasaki Y, Okuno Y, Goto Y, Iida M, Yajima I, Ohgami N, Kato M.  Peptides containing the MXXCW motif inhibit oncogenic RET kinase activity with a novel mechanism of action.  Am J Cancer Res  2020    PubMed ID: 32064171
12100  Okubo S, Ohta T, Shoyama Y, Uto T.  Arctigenin suppresses cell proliferation via autophagy inhibition in hepatocellular carcinoma cells.  J Nat Med  2020    PubMed ID: 32207025
12136  Choodej, Khanitha Pudhom  Cycloartane triterpenoids from the leaves of Euphorbia neriifolia  Phytochemistry Letters  2020   
12149  Kruthi Suvarna, Kaori Honda, Makoto Muroi, Yasumitsu Kondoh, Nobumoto Watanabe, Hiroyuki Osada  Identification of Target Protein for Bio-active Small Molecule Using Photo-cross Linked Beads and MALDI-TOF Mass Spectrometry   Bio Protoc  2020  10 
10510  Kenward Vong, Tomoya Yamamoto, Tsung-che Changa and Katsunori Tanaka   Bioorthogonal release of anticancer drugs via gold-triggered 2-alkynylbenzamide cyclization  Chemical Science  2020  11:10928-10933 
12989  Endo M, Ohba K, Sato S, Yokota Y, Takahashi K.  Increased soluble (pro)renin receptor protein by autophagy inhibition in cultured cancer cells.  Genes Cells  2020    PubMed ID: 32314441
13051  Sakaguchi M, Kitaguchi D, Morinami S, Kurashiki Y, Hashida H, Miyata S, Yamaguchi M, Sakai M, Murata N, Tanaka S.  Berberine-induced nucleolar stress response in a human breast cancer cell line.  Biochem Biophys Res Commun  2020    PubMed ID: 32475643
13095  Mai NNH, Yamaguchi Y, Choijookhuu N, Matsumoto J, Nanashima A, Takagi H, Sato K, Tuan LQ, Hishikawa Y.  Photodynamic Therapy Using a Novel Phosphorus Tetraphenylporphyrin Induces an Anticancer Effect via Bax/Bcl-xL-related Mitochondrial Apoptosis in Biliary Cancer Cells.  Acta Histochem Cytochem  2020    PubMed ID: 32873990
13270  Kiyomi A, Miyakawa R, Matsumoto J, Yamazaki K, Imai S, Yuan B, Hirano T, Sugiura M.  Potent antitumor activity of cepharanthine against triple-negative breast cancer spheroids compared with tetrandrine.  Oncol Lett  2020    PubMed ID: 33101499
13317  Fujita K, Kamiya M, Yoshioka T, Ogasawara A, Hino R, Kojima R, Ueo H, Urano Y.  Rapid and Accurate Visualization of Breast Tumors with a Fluorescent Probe Targeting α-Mannosidase 2C1.  ACS Cent Sci  2020    PubMed ID: 33376783
13585  Tottori N, Nisisako T.  Particle/cell separation using sheath-free deterministic lateral displacement arrays with inertially focused single straight input  Lab Chip  2020  20(11):1999-2008  PubMed ID: 32373868
13593  Ciftci HI, Can M, Ellakwa DE, Suner SC, Ibrahim MA, Oral A, Sekeroglu N, Özalp B, Otsuka M, Fujita M, Alparslan M, Radwan MO.  Anticancer activity of Turkish marine extracts: a purple sponge extract induces apoptosis with multitarget kinase inhibition activity  Invest New Drugs  2020  38(5):1326-1333  PubMed ID: 32062733
13595  Guo W, Mashimo Y, Kobatake E, Mie M.  Construction of DNA-displaying nanoparticles by enzymatic conjugation of DNA and elastin-like polypeptides using a replication initiation protein  Nanotechnology  2020  31(25):255102  PubMed ID: 32176872
14364  Kohzaki M, Ootsuyama A, Sun L, Moritake T, Okazaki R.  Human RECQL4 represses the RAD52-mediated single-strand annealing pathway after ionizing radiation or cisplatin treatment  Int J Cancer  2020  146(11):3098-3113  PubMed ID: 31495919
14854  Terasaki A, Kurokawa H, Ito H, Komatsu Y, Matano D, Terasaki M, Bando H, Hara H, Matsui H.  Elevated Production of Mitochondrial Reactive Oxygen Species via Hyperthermia Enhanced Cytotoxic Effect of Doxorubicin in Human Breast Cancer Cell Lines MDA-MB-453 and MCF-7  Int J Mol Sci  2020  21(24):9522  PubMed ID: 33333736
11195  Okahashi N, Maeda K, Kawana S, Iida J, Shimizu H, Matsuda F.  Sugar phosphate analysis with baseline separation and soft ionization by gas chromatography-negative chemical ionization-mass spectrometry improves flux estimation of bidirectional reactions in cancer cells.  Metab. Eng  2019  51:43-49  PubMed ID: 30176394
4053  Ali TFS, Ciftci HI, Radwan MO, Koga R, Ohsugi T, Okiyama Y, Honma T, Nakata A, Ito A, Yoshida M, Fujita M, Otsuka M.  New SIRT2 inhibitors: Histidine-based bleomycin spin-off  Bioorg Med Chem  2019  27:1767-1775  PubMed ID: 30885568
11297  Mie M, Matsumoto R, Mashimo Y, Cass AEG, Kobatake E.  Development of drug-loaded protein nanoparticles displaying enzymatically-conjugated DNA aptamers for cancer cell targeting.  Mol. Biol. Rep.  2019    PubMed ID: 30421127
11308  Imamura T, Isozumi N, Higashimura Y, Miyazato A, Mizukoshi H, Ohki S, Mori M.  Isolation of amaranthin synthetase from Chenopodium quinoa and construction of an amaranthin production system using suspension-cultured tobacco BY-2 cells.  Plant Biotechnol. J.  2019    PubMed ID: 30451369
11360  Futami K, Kimoto M, Lim YWS, Hirao I.  Genetic Alphabet Expansion Provides Versatile Specificities and Activities of Unnatural-Base DNA Aptamers Targeting Cancer Cells.  Mol Ther Nucleic Acids  2019    PubMed ID: 30594072
11324  Lin Y, Chen Y, Ukaji T, Okada S, Umezawa K.  Isolation of ketomycin from Actinomycetes as an inhibitor of 2D and 3D cancer cell invasion.  J. Antibiot.  2019    PubMed ID: 30510246
11375  Handa T, Katayama A, Yokobori T, Yamane A, Fujii T, Obayashi S, Kurozumi S, Kawabata-Iwakawa R, Gombodorj N, Nishiyama M, Asao T, Shirabe K, Kuwano H, Oyama T.  Carboxypeptidase A4 accumulation is associated with an aggressive phenotype and poor prognosis in triple-negative breast cancer.  Int. J. Oncol.  2019    PubMed ID: 30628666
11381  Win NN, Kyaw MM, Prema, Ngwe H, Ito T, Asakawa Y, Okamoto Y, Tanaka M, Abe I, Morita H.  Dinorcassane Diterpenoid from Boesenbergia rotunda Rhizomes Collected in Lower Myanmar.  Chem. Biodivers.  2019    PubMed ID: 30645035
11472  Suzuki S, Fukuda T, Nagayasu S, Nakanishi J, Yoshida K, Hirata-Tsuchiya S, Nakao Y, Sano T, Yamashita A, Yamada S, Ohta K, Shiba H, Nishimura F.  Dental pulp cell-derived powerful inducer of TNF-α comprises PKR containing stress granule rich microvesicles.  Sci Rep  2019    PubMed ID: 30846715
4759  Halil I. Ciftci, Mohamed O. Radwan, Safiye E. Ozturk, N. Gokce Ulusoy, Ece Sozer, Doha E. Ellakwa, Zeynep Ocak, Mustafa Can, Taha F.S. Ali, Howaida I. Abd-Alla, Nurettin Yayli, Hiroshi Tateishi, Masami Otsuka and Mikako Fujita  Design, Synthesis and Biological Evaluation of Pentacyclic Triterpene Derivatives: Optimization of Anti-ABL Kinase Activity  Molecules  2019  24:3535  PubMed ID: 31574910
4760  Mohamed O. Radwan, Halil I. Ciftci, Taha F. S. Ali , Doha E. Ellakwa, Ryoko Koga, Hiroshi Tateishi, Akiko Nakata, Akihiro Ito, Minoru Yoshida, Yoshinari Okamoto, Mikako Fujita and Masami Otsuka  Antiproliferative S-Trityl-l-Cysteine -Derived Compounds as SIRT2 Inhibitors: Repurposing and Solubility Enhancement  Molecules  2019  24:3295  PubMed ID: 31510043
11611  Takahashi T, Honsho M, Abe Y, Fujiki Y.  Plasmalogen mediates integration of adherens junction.  J. Biochem.  2019    PubMed ID: 31236591
11724  Othman DIA, Selim KB, El-Sayed MA, Tantawy AS, Amen Y, Shimizu K, Okauchi T, Kitamura M.  Design, Synthesis and Anticancer Evaluation of New Substituted Thiophene-Quinoline Derivatives.  Bioorg. Med. Chem.  2019    PubMed ID: 31416740
11851  Fujitani N, Yoneda A, Takahashi M, Takasawa A, Aoyama T, Miyazaki T.  Silencing of Glutathione S-Transferase Pi Inhibits Cancer Cell Growth via Oxidative Stress Induced by Mitochondria Dysfunction.  Sci Rep  2019    PubMed ID: 31611630
11864  Matsumoto Y, Kuriki H, Kitamura T, Takahashi D, Toshima K.  Total Synthesis and Structure-Activity Relationship Study of Vineomycin A1.  J. Org. Chem.  2019    PubMed ID: 31642324
6837  Bouallagui Z, Mahmoudi A, Maalej A, Hadrich F, Isoda H, Sayadi S.  Contribution of Major Polyphenols to the Antioxidant Profile and Cytotoxic Activity of Olive Leaves.  Anticancer Agents Med Chem  2019  19(13):1651-1657  PubMed ID: 31038081
6942  Mahmoud Abdel-Hamid et al  The biological activity of fermented milk produced by Lactobacillus casei ATCC 393 during cold storage  International Dairy Journal   2019  91:1-8 
9810  Junko Shibato, Fumiko Takenoya, Takahiro Hirabayashi, Ai Kimura, Yusuke Iwasaki, Yoko Toyoda, Motohide Hori, Shigeru Tamogami, Randeep Rakwal, Seiji Shioda  Towards Identification of Bioactive Compounds in Cold Vacuum Extracted Double Cherry Blossom (Gosen-Sakura) Leaves  Plant Signal Behav  2019  14(10):e1644594  PubMed ID: 31342859
10468  R. SowmiyaTanakorn OsotchanDakrong Pissuwan  The Impact of Gold Nanoparticles with Low Energy Irradiation Treatment on Temperature Induction and Cell Viability of Breast Cancer Cell  International Conference on Nanomedicine  2019  86-93 
10357  Belgin Sever, Mehlika Dilek Altıntop, Mohamed O Radwan, Ahmet Özdemir, Masami Otsuka, Mikako Fujita, Halil I Ciftci  Design, synthesis and biological evaluation of a new series of thiazolyl-pyrazolines as dual EGFR and HER2 inhibitors  Eur J Med Chem  2019  82:111648  PubMed ID: 31493743
12517  Satria D, Amen Y, Niwa Y, Ashour A, Allam AE, Shimizu K.  Lucidumol D, a new lanostane-type triterpene from fruiting bodies of Reishi (Ganoderma lingzhi)  Nat Prod Res  2019  33(2):189-195  PubMed ID: 29457741
12559  Li F, Kitajima S, Kohno S, Yoshida A, Tange S, Sasaki S, Okada N, Nishimoto Y, Muranaka H, Nagatani N, Suzuki M, Masuda S, Thai TC, Nishiuchi T, Tanaka T, Barbie DA, Mukaida N, Takahashi C.  Retinoblastoma Inactivation Induces a Protumoral Microenvironment via Enhanced CCL2 Secretion  Cancer Res  2019  79(15):3903-3915  PubMed ID: 31189648
12958  Yu B, Yuan B, Kiyomi A, Kikuchi H, Hayashi H, Hu X, Okazaki M, Sugiura M, Hirano T, Pei X, Takagi N.  Differentiation induction of human breast cancer cells by arsenite in combination with tetrandrine.  Am J Transl Res  2019    PubMed ID: 31934280
9501  Shiota M, Naya M, Yamamoto T, Hishiki T, Tani T, Takahashi H, Kubo A, Koike D, Itoh M, Ohmura M, Kabe Y, Sugiura Y, Hiraoka N, Morikawa T, Takubo K, Suina K, Nagashima H, Sampetrean O, Nagano O, Saya H, Yamazoe S, Watanabe H, Suematsu M.  Gold-nanofève surface-enhanced Raman spectroscopy visualizes hypotaurine as a robust anti-oxidant consumed in cancer survival.  Nat Commun  2018  9:1561  PubMed ID: 29674746
10700  Taniguchi K, Matsumura K, Kageyama S, Ii H, Ashihara E, Chano T, Kawauchi A, Yoshiki T, Nakata S.  Prohibitin-2 is a novel regulator of p21WAF1/CIP1 induced by depletion of γ-glutamylcyclotransferase.  Biochem. Biophys. Res. Commun.  2018  496:218-224  PubMed ID: 29307834
10706  Bao H, Bai T, Takata K, Yokobori T, Ohnaga T, Hisada T, Maeno T, Bao P, Yoshida T, Kumakura Y, Honjo H, Sakai M, Sohda M, Fukuchi M, Altan B, Handa T, Ide M, Miyazaki T, Ogata K, Oyama T, Shimizu K, Mogi A, Asao T, Shirabe K, Kuwano H, Kaira K.  High expression of carcinoembryonic antigen and telomerase reverse transcriptase in circulating tumor cells is associated with poor clinical response to the immune checkpoint inhibitor nivolumab.  Oncol Lett  2018  15:3061-3067  PubMed ID: 29435038
10735  Suvarna K, Honda K, Kondoh Y, Osada H, Watanabe N.  Identification of a small-molecule ligand of β-arrestin1 as an inhibitor of stromal fibroblast cell migration accelerated by cancer cells.  Cancer Med  2018  7:883-893  PubMed ID: 29380537
10760  Oo PS, Yamaguchi Y, Sawaguchi A, Tin Htwe Kyaw M, Choijookhuu N, Noor Ali M, Srisowanna N, Hino SI, Hishikawa Y.  Estrogen Regulates Mitochondrial Morphology through Phosphorylation of Dynamin-related Protein 1 in MCF7 Human Breast Cancer Cells.  Acta Histochem Cytochem  2018  51:21-31  PubMed ID: 29622847
10845  Taniguchi K, Matsumura K, Ii H, Kageyama S, Ashihara E, Chano T, Kawauchi A, Yoshiki T, Nakata S.  Depletion of gamma-glutamylcyclotransferase in cancer cells induces autophagy followed by cellular senescence.  Am J Cancer Res  2018  8:650-661  PubMed ID: 29736310
11113  Kawai T, Ota N, Imasato A, Shirasaki Y, Otsuka K, Tanaka Y.  Profiling of N-linked glycans from 100 cells by capillary electrophoresis with large-volume dual preconcentration by isotachophoresis and stacking.  J Chromatogr A  2018  1565:138-144  PubMed ID: 29945790
11160  Languon S, Tuffour I, Quayson EE, Appiah-Opong R, Quaye O.  In Vitro Evaluation of Cytotoxic Activities of Marketed Herbal Products in Ghana.  J Evid Based Integr Med  2018    PubMed ID: 30088418
11164  Mogi K, Hayashida K, Yamamoto T.  Damage-less Handling of Exosomes Using an Ion-depletion Zone in a Microchannel.  Anal Sci  2018  34(8):875-880  PubMed ID: 30101880
4421  Mohamed S. Mohamed et al  Ultra-Low Power NIR Laser-Triggered Phototherapy and μCT Imaging of Breast Cancer In Vivo  IEEE Xplore  2018  14 February 
4422  Enos Tangke Arung, Rudianto Amirta, Qinchang Zhu, Yhiya Amen, Kuniyoshi Shimizu  Effect of wood, bark and leaf extracts of Macaranga trees on cytotoxic activity in some cancer and normal cell lines  Journal of the Indian Academy of Wood Science  2018  5, 115–119 
4286  Yoshihara A, Sekine R, Ueki T, Kondo Y, Sunaga Y, Nakaji-Hirabayashi T, Teramura Y, Takai M.  Rapid and highly efficient capture and release of cancer cells using polymeric microfibers immobilized with enzyme-cleavable peptides.  Acta Biomater  2018    PubMed ID: 29223702
4287  Veeranarayanan S, Mohamed MS, Poulose AC, Rinya M, Sakamoto Y, Maekawa T, Kumar DS.  Photodynamic therapy at ultra-low NIR laser power and X-Ray imaging using Cu3BiS3 nanocrystals.  Theranostics  2018    PubMed ID: 30555543
4288  Khatun A, Shimozawa M, Kito H, Kawaguchi M, Fujimoto M, Ri M, Kajikuri J, Niwa S, Fujii M, Ohya S.  Transcriptional Repression and Protein Degradation of the Ca2+-Activated K+ Channel KCa1.1 by Androgen Receptor Inhibition in Human Breast Cancer Cells.  Front Physiol  2018    PubMed ID: 29713287
4372  Ito T, Rakainsa SK, Nisa K, Morita H.  Three new abietane-type diterpenoids from the leaves of Indonesian Plectranthus scutellarioides.  Fitoterapia  2018  127:146-150  PubMed ID: 29447983
14901  Enjoji S, Yabe R, Tsuji S, Yoshimura K, Kawasaki H, Sakurai M, Sakai Y, Takenouchi H, Yoshino S, Hazama S, Nagano H, Oshima H, Oshima M, Vitek MP, Matsuura T, Hippo Y, Usui T, Ohama T, Sato K.  Stemness Is Enhanced in Gastric Cancer by a SET/PP2A/E2F1 Axis  Mol Cancer Res  2018  16(3):554-563  PubMed ID: 29330298
7013  Fujimoto M, Takii R, Takaki E, Katiyar A, Nakato R, Shirahige K, Nakai A.  The HSF1-PARP13-PARP1 complex facilitates DNA repair and promotes mammary tumorigenesis.  Nat Commun  2017  8:1638  PubMed ID: 29158484
9925  Fujimoto M, Inoue T, Kito H, Niwa S, Suzuki T, Muraki K, Ohya S.  Transcriptional repression of HER2 by ANO1 Cl- channel inhibition in human breast cancer cells with resistance to trastuzumab.  Biochem. Biophys. Res. Commun.  2017  482:188-194  PubMed ID: 27838298
10066  Tanaka S, Suzuki K, Sakaguchi M.  The prolyl oligopeptidase inhibitor SUAM-14746 attenuates the proliferation of human breast cancer cell lines in vitro.  Breast Cancer  2017  24:658-666  PubMed ID: 28070831
10175  Tatebe H, Murayama S, Yonekura T, Hatano T, Richter D, Furuya T, Kataoka S, Furuita K, Kojima C, Shiozaki K.  Substrate specificity of TOR complex 2 is determined by a ubiquitin-fold domain of the Sin1 subunit.  Elife  2017  6:  PubMed ID: 28264193
10302  Kitajima S, Yoshida A, Kohno S, Li F, Suzuki S, Nagatani N, Nishimoto Y, Sasaki N, Muranaka H, Wan Y, Thai TC, Okahashi N, Matsuda F, Shimizu H, Nishiuchi T, Suzuki Y, Tominaga K, Gotoh N, Suzuki M, Ewen ME, Barbie DA, Hirose O, Tanaka T, Takahashi C.  The RB-IL-6 axis controls self-renewal and endocrine therapy resistance by fine-tuning mitochondrial activity.  Oncogene  2017  36:5145-5157  PubMed ID: 28481867
10339  Nashimoto Y, Hayashi T, Kunita I, Nakamasu A, Torisawa YS, Nakayama M, Takigawa-Imamura H, Kotera H, Nishiyama K, Miura T, Yokokawa R.  Integrating perfusable vascular networks with a three-dimensional tissue in a microfluidic device.  Integr Biol (Camb)  2017  9:506-518  PubMed ID: 28561127
10379  Yao M, Yuan B, Wang X, Sato A, Sakuma K, Kaneko K, Komuro H, Okazaki A, Hayashi H, Toyoda H, Pei X, Hu X, Hirano T, Takagi N.  Synergistic cytotoxic effects of arsenite and tetrandrine in human breast cancer cell line MCF-7.  Int. J. Oncol.  2017  51:587-598  PubMed ID: 28656245
10492  Wakahara M, Sakabe T, Kubouchi Y, Hosoya K, Hirooka Y, Yurugi Y, Nosaka K, Shiomi T, Nakamura H, Umekita Y.  Subcellular Localization of Maspin Correlates with Histone Deacetylase 1 Expression in Human Breast Cancer.  Anticancer Res.  2017  37:5071-5077  PubMed ID: 28870936
10504  Kawabata H, Azuma K, Ikeda K, Sugitani I, Kinowaki K, Fujii T, Osaki A, Saeki T, Horie-Inoue K, Inoue S.  TRIM44 Is a Poor Prognostic Factor for Breast Cancer Patients as a Modulator of NF-κB Signaling.  Int J Mol Sci  2017  18:  PubMed ID: 28885545
10558  Mellini P, Itoh Y, Tsumoto H, Li Y, Suzuki M, Tokuda N, Kakizawa T, Miura Y, Takeuchi J, Lahtela-Kakkonen M, Suzuki T.  Potent mechanism-based sirtuin-2-selective inhibition by an in situ-generated occupant of the substrate-binding site, "selectivity pocket" and NAD+-binding site.  Chem Sci  2017  8:6400-6408  PubMed ID: 28989670
4533  Ankita Borah, Vivekanandan Palaninathan, Aswathy Ravindran Girija, Sivakumar Balasubramanian, Ankit K. Rochani, Toru Maekawa and D. Sakthi Kumar  Poly-lactic-co-glycolic acid Nanoformulation of Small Molecule Antagonist GANT61 for Cancer Annihilation by Modulating Hedgehog Pathway  NanoWorld Journal  2017  3:1-10 
4536    Engineering a three-dimensional tissue model with a perfusable vasculature in a microfluidic device  IEEE Xplore  2017  22-26 
4547  Takasugi M, Okada R, Takahashi A, Virya Chen D, Watanabe S, Hara E.  Small extracellular vesicles secreted from senescent cells promote cancer cell proliferation through EphA2.  Nat Commun  2017  8:15729  PubMed ID: 28585531
14382  Handa T, Katayama A, Yokobori T, Yamane A, Horiguchi J, Kawabata-Iwakawa R, Rokudai S, Bao P, Gombodorj N, Altan B, Kaira K, Asao T, Kuwano H, Nishiyama M, Oyama T.  Caspase14 expression is associated with triple negative phenotypes and cancer stem cell marker expression in breast cancer patients  J Surg Oncol  2017  116(6):706-715  PubMed ID: 28570747
14384  Miyasato Y, Shiota T, Ohnishi K, Pan C, Yano H, Horlad H, Yamamoto Y, Yamamoto-Ibusuki M, Iwase H, Takeya M, Komohara Y.  High density of CD204-positive macrophages predicts worse clinical prognosis in patients with breast cancer  Cancer Sci  2017  108(8):1693-1700  PubMed ID: 28574667
14633  Shiraishi A, Tachi K, Essid N, Tsuboi I, Nagano M, Kato T, Yamashita T, Bando H, Hara H, Ohneda O.  Hypoxia promotes the phenotypic change of aldehyde dehydrogenase activity of breast cancer stem cells  Cancer Sci  2017  108(3):362-372  PubMed ID: 28012234
14648  Yoshida A, Kitajima S, Li F, Cheng C, Takegami Y, Kohno S, Wan YS, Hayashi N, Muranaka H, Nishimoto Y, Nagatani N, Nishiuchi T, Thai TC, Suzuki S, Nakao S, Tanaka T, Hirose O, Barbie DA, Takahashi C.  MicroRNA-140 mediates RB tumor suppressor function to control stem cell-like activity through interleukin-6  Oncotarget  2017  8(8):13872-13885  PubMed ID: 28099924
14755  Hayashi K, Sato Y, Sakamoto W, Yogo T.  Theranostic Nanoparticles for MRI-Guided Thermochemotherapy: "Tight" Clustering of Magnetic Nanoparticles Bo  ACS Biomater Sci Eng  2017  3(1):95-105  PubMed ID: 33429683
14757  Yamauchi I, Sakane Y, Fukuda Y, Fujii T, Taura D, Hirata M, Hirota K, Ueda Y, Kanai Y, Yamashita Y, Kondo E, Sone M, Yasoda A, Inagaki N.  Clinical Features of Nivolumab-Induced Thyroiditis: A Case Series Study  Thyroid  2017  27(7):894-901  PubMed ID: 28537531
7207  Ninomiya K, Maruyama H, Ogino C, Takahashi K, Shimizu N.  Sonocatalytic injury of cancer cells attached on the surface of a nickel-titanium dioxide alloy plate.  Ultrason Sonochem  2016  28:1-6  PubMed ID: 26384876
7208  Ninomiya K, Yamashita T, Tanabe Y, Imai M, Takahashi K, Shimizu N.  Targeted and ultrasound-triggered cancer cell injury using perfluorocarbon emulsion-loaded liposomes endowed with cancer cell-targeting and fusogenic capabilities.  Ultrason Sonochem  2016  28:54-61  PubMed ID: 26384883
9691  Sasaki S, Kanzaki M, Kaneko T.  Calcium influx through TRP channels induced by short-lived reactive species in plasma-irradiated solution.  Sci Rep  2016  6:25728  PubMed ID: 27169489
9818  Kanzaki H, Shinohara F, Suzuki M, Wada S, Miyamoto Y, Yamaguchi Y, Katsumata Y, Makihira S, Kawai T, Taubman MA, Nakamura Y.  A-Disintegrin and Metalloproteinase (ADAM) 17 Enzymatically Degrades Interferon-gamma.  Sci Rep  2016  6:32259  PubMed ID: 27573075
9836  Yanagawa T, Denda K, Inatani T, Fukushima T, Tanaka T, Kumaki N, Inagaki Y, Komada M.  Deficiency of X-Linked Protein Kinase Nrk during Pregnancy Triggers Breast Tumor in Mice.  Am. J. Pathol.  2016  186:2751-60  PubMed ID: 27634343
9877  Tanaka S, Sakaguchi M, Yoneyama H, Usami Y, Harusawa S.  Histamine H3 receptor antagonist OUP-186 attenuates the proliferation of cultured human breast cancer cell lines.  Biochem. Biophys. Res. Commun.  2016  480:479-485  PubMed ID: 27773822
9880  Poulose AC, Veeranarayanan S, Mohamed MS, Aburto RR, Mitcham T, Bouchard RR, Ajayan PM, Sakamoto Y, Maekawa T, Kumar DS.  Multifunctional Cu2-xTe Nanocubes Mediated Combination Therapy for Multi-Drug Resistant MDA MB 453.  Sci Rep  2016  6:35961  PubMed ID: 27775048
9992  Khatun A, Fujimoto M, Kito H, Niwa S, Suzuki T, Ohya S.  Down-Regulation of Ca2+-Activated K⁺ Channel KCa1.1 in Human Breast Cancer MDA-MB-453 Cells Treated with Vitamin D Receptor Agonists.  Int J Mol Sci  2016  17:  PubMed ID: 27973439
10024  Matsumura K, Nakata S, Taniguchi K, Ii H, Ashihara E, Kageyama S, Kawauchi A, Yoshiki T.  Depletion of γ-glutamylcyclotransferase inhibits breast cancer cell growth via cellular senescence induction mediated by CDK inhibitor upregulation.  BMC Cancer  2016  16:748  PubMed ID: 27658708
10861    Targeting CD44, ABCG2 and CD133 markers using aptamers: in silico analysis of CD133 extracellular domain 2 and its aptamer  RSC Adv.  2016  6, 32115-32123 
10877    Development of an ‘OFF-ON-OFF’ fluorescent pH sensor suitable for the study of intracellular pH  Tetrahedron  2016  72, 4925-4930 
10908    Extracts of Codiaeum variegatum (L.) A. Juss is Cytotoxic on Human Leukemic, Breast and Prostate Cancer Cell Lines  Journal of Applied Pharmaceutical Science  2016  6, 087-093 
9118  Yosuke Amagai, Tomoko Fujiyuki, Misako Yoneda, Koichiro Shoji, Yoichi Furukawa, Hiroki Sato, Chieko Kai  Oncolytic Activity of a Recombinant Measles Virus, Blind to Signaling Lymphocyte Activation Molecule, Against Colorectal Cancer Cells  Sci Rep  2016  6, 24572  PubMed ID: 27090874
12655  Kano H, Takayama T, Midorikawa Y, Nagase H.  Promoter hypomethylation of RAR-related orphan receptor α 1 is correlated with unfavorable clinicopathological features in patients with colorectal cancer  Biosci Trends  2016  10(3):202-9.  PubMed ID: 27301432
12686  Taira, N., Iwasaki, H., Inafuku, M., Saitoh, S., & Oku, H.  Enhanced cytotoxicity of nitidine against camptothecin‐resistant A549 cells  Traditional & Kampo Medicine  2016  3(1):33-40 
12882  Kikuchi M, Yamashita K, Waraya M, Minatani N, Ushiku H, Kojo K, Ema A, Kosaka Y, Katoh H, Sengoku N, Enomoto T, Tanino H, Sawanobori M, Watanabe M.  Epigenetic regulation of ZEB1-RAB25/ESRP1 axis plays a critical role in phenylbutyrate treatment-resistant breast cancer  Oncotarget  2016  7(2):1741-53.  PubMed ID: 26646320
12887  Tachi K, Shiraishi A, Bando H, Yamashita T, Tsuboi I, Kato T, Hara H, Ohneda O.  FOXA1 expression affects the proliferation activity of luminal breast cancer stem cell populations  Cancer Sci  2016  107(3):281-9  PubMed ID: 26708273
12912  Yoshimura T, Hamada T, Hijioka H, Souda M, Hatanaka K, Yoshioka T, Yamada S, Tsutsui M, Umekita Y, Nakamura N, Tanimoto A.  PCP4/PEP19 promotes migration, invasion and adhesion in human breast cancer MCF-7 and T47D cells  Oncotarget  2016  7(31):49065-49074  PubMed ID: 27384474
13474  Kume K, Ikeda M, Miura S, Ito K, Sato KA, Ohmori Y, Endo F, Katagiri H, Ishida K, Ito C, Iwaya T, Nishizuka SS.  α-Amanitin Restrains Cancer Relapse from Drug-Tolerant Cell Subpopulations via TAF15  Sci Rep  2016  6:25895  PubMed ID: 27181033
14128  REGINA APPIAH-OPONG, ISAAC KWADWO ASANTE, DORCAS OSEI SAFO, ISAAC TUFFOUR, EBENEZER OFORI- ATTAH, TAKUHIRO UTO, ALEXANDER KWADWO NYARKO  Cytotoxic effects of Albizia zygia (DC) JF Macbr, a Ghanaian medicinal plant, against human T-lymphoblast-like leukemia, prostate and breast cancer cell lines  International Journal of Pharmacy and Pharmaceutical Sciences  2016  8 
14158  Johmura Y, Sun J, Kitagawa K, Nakanishi K, Kuno T, Naiki-Ito A, Sawada Y, Miyamoto T, Okabe A, Aburatani H, Li S, Miyoshi I, Takahashi S, Kitagawa M, Nakanishi M.  SCF(Fbxo22)-KDM4A targets methylated p53 for degradation and regulates senescence  Nat Commun  2016  7:10574  PubMed ID: 26868148
7106  Morizane M, Kawasaki Y, Miura T, Yagi K, Esumi S, Kitamura Y, Sendo T.  Photoinitiator-Initiated Estrogenic Activity in Human Breast Cancer Cell Line MCF-7.  J. Toxicol. Environ. Health Part A  2015  78:1450-60  PubMed ID: 26692070
7173  Nakaoka E, Tanaka S, Onda K, Sugiyama K, Hirano T.  Effects of Vitamin K3 and K5 on Daunorubicin-resistant Human T Lymphoblastoid Leukemia Cells.  Anticancer Res.  2015  35:6041-8  PubMed ID: 26504027
7237  Zhu Q, Bang TH, Ohnuki K, Sawai T, Sawai K, Shimizu K.  Inhibition of neuraminidase by Ganoderma triterpenoids and implications for neuraminidase inhibitor design.  Sci Rep  2015  5:13194  PubMed ID: 26307417
7462  Tomita T, Ieguchi K, Sawamura T, Maru Y.  Human serum amyloid A3 (SAA3) protein, expressed as a fusion protein with SAA2, binds the oxidized low density lipoprotein receptor.  PLoS ONE  2015  10:e0118835  PubMed ID: 25738827
7475  Watari A, Hashegawa M, Muangman T, Yagi K, Kondoh M.  Use of cell-based screening to identify small-molecule compounds that modulate claudin-4 expression.  Biotechnol. Lett.  2015  37:1177-85  PubMed ID: 25700824
7515  Subramanian N, Kanwar JR, Athalya PK, Janakiraman N, Khetan V, Kanwar RK, Eluchuri S, Krishnakumar S.  EpCAM aptamer mediated cancer cell specific delivery of EpCAM siRNA using polymeric nanocomplex.  J. Biomed. Sci.  2015  22:4  PubMed ID: 25576037
7525  F Acheampong, C Larbie, FKN Arthur, R Appiah-Opong, I. Tuffour  Antioxidant and anticancer study of Ageratum cornyzoides aqueous extracts.  J Global Biosciences  2015  4:1804-1815 
7545  Masanari Umemura, Mayumi Katsumata, Itaru Sato, Akane Nagasako, Haruki Aoyama, Ayako Makino, Makoto Ohtake, Kayoko Oda, Kosuke Matsuo, Haruki Eguchi, Yoshihiro Ishikawa  Abstract 4398: Methotrexate derivative with intrinsic magnetism.  Cancer Res.  2015  75:4398-4398 
7560  Shimodaira S, Hirabayashi K, Koya T, Higuchi Y, Sano K  Standard WT1 Expression Using Immunohistochemistry.  J Mol Biomark Diagn  2015  7:266 
10193  Jun Matsumoto, Noritaka Ariyoshi, Masahiro Sakakibara, Takeo Nakanishi, Yoshiyuki Okubo, Nobumitsu Shiina, Kaoru Fujisaki, Takeshi Nagashima, Yukio Nakatani, Ikumi Tamai, Harumi Yamada, Hiroshi Takeda, Itsuko Ishii  Organic Anion Transporting Polypeptide 2B1 Expression Correlates With Uptake of estrone-3-sulfate and Cell Proliferation in Estrogen Receptor-Positive Breast Cancer Cells  Drug Metab Pharmacokinet  2015  30(2):133-41  PubMed ID: 25857231
14986  Subramanian N, Kanwar JR, Kanwar RK, Sreemanthula J, Biswas J, Khetan V, Krishnakumar S.  EpCAM Aptamer-siRNA Chimera Targets and Regress Epithelial Cancer  PLoS One  2015  10(7):e0132407  PubMed ID: 26176230
15007  Felix Acheampong, Christopher Larbie, Regina Appiah-Opong,Fareed K.N.Arthur1andIsaac Tuffour  In vitroAntioxidant and Anticancer Properties of Hydroethanolic Extracts and Fractions of Ageratum conyzoides  European Journal of Medicinal Plants  2015  7:205-214 
15012  Wong CP, Seki A, Horiguchi K, Shoji T, Arai T, Nugroho AE, Hirasawa Y, Sato F, Kaneda T, Morita H.  Bisleuconothine A Induces Autophagosome Formation by Interfering with AKT-mTOR Signaling Pathway  J Nat Prod  2015  78(7):1656-62  PubMed ID: 26176165
15034  Selma Etteieb, Atsushi Kawachi, Junkyu Han, Jamila Tarhouni, Hiroko Isoda  Estrogenic Activity Assessment in Environmental Matrices by Means of In Vitro Cell-Based Bioassays Coupled With Molecular Investigation  CLEAN - Soil, Air, Water  2015  43:1279-1288 
15127  Kan S, Koido S, Okamoto M, Hayashi K, Ito M, Kamata Y, Komita H, Ishidao T, Nagasaki E, Homma S.  Gemcitabine treatment enhances HER2 expression in low HER2-expressing breast cancer cells and enhances the antitumor effects of trastuzumab emtansine  Oncol Rep  2015  34(1):504-10  PubMed ID: 25976081
15145  Mira A, Shimizu K.  In vitro Cytotoxic Activities and Molecular Mechanisms of Angelica shikokiana Extract and its Isolated Compounds  Pharmacogn Mag  2015  11(Suppl 4):S564-9  PubMed ID: 27013795
12333  Karmakar UK, Ishikawa N, Toume K, Arai MA, Sadhu SK, Ahmed F, Ishibashi M.  Sesquiterpenes with TRAIL-resistance overcoming activity from Xanthium strumarium  Bioorg Med Chem  2015  23(15):4746-4754  PubMed ID: 26081757
15181  Yoshitaka Koseki, Yoshikazu Ikuta, Tatsuya Murakami, Tsunenobu Onodera, Hidetoshi Oikawa, Liman Cong, Hiroshi Tada, Kohsuke Gonda, Noriaki Ohuchi, Hitoshi Kasai  Cytotoxicity of Pure Nanodrugs of SN-38 and Podophyllotoxin Dimers in Human Cancer HepG2, KPL-4, and MCF-7 Cells  Molecular Crystals and Liquid Crystals  2015  622:1-5 
15209  Kasai A, Arafuka S, Koshiba N, Takahashi D, Toshima K.  Systematic synthesis of low-molecular weight fucoidan derivatives and their effect on cancer cells  Org Biomol Chem  2015  13(42):10556-68  PubMed ID: 26340595
15224  MASANARI UMEMURA, Mayumi Katsumata, Itaru Sato, Akane Nagasako, Haruki Aoyama, Ayako Makino, Makoto Ohtake, Kayoko Oda, Kosuke Matsuo, Haruki Eguchi and Yoshihiro Ishikawa  Abstract 4398: Methotrexate derivative with intrinsic magnetism  AACR 106th Annual Meeting  2015  April 18-22 
15425  Sreejith Raveendran, Neha Chauhan, Vivekanandan Palaninathan, Yutaka Nagaoka, Yasuhiko Yoshida, Toru Maekawa, D. Sakthi Kumar  Extremophilic Polysaccharide for Biosynthesis and Passivation of Gold Nanoparticles and Photothermal Ablation of Cancer Cells  Particle & Particle Systems Characterization  2015  32:54-64 
4056  Xu B, Ju Y, Cui Y, Song G, Iwase Y, Hosoi A, Morita Y.  tLyP-1-conjugated Au-nanorod@SiO(2) core-shell nanoparticles for tumor-targeted drug delivery and photothermal therapy.  Langmuir  2014  30:7789-97  PubMed ID: 24921672
15803  M. Sheikh Mohamed, Srivani Veeranarayanan, Hiroaki Minegishi, Yasushi Sakamoto, Yasuhiro Shimane, Yutaka Nagaoka, Atsushi Aki, Aby Cheruvathoor Poulose, Akinobu Echigo, Yasuhiko Yoshida, Toru Maekawa, D. Sakthi Kumar  Cytological and Subcellular Response of Cells Exposed to the Type-1 RIP Curcin and its Hemocompatibility Analysis  Scientific Reports  2014  4 
15859  Hamada T, Souda M, Yoshimura T, Sasaguri S, Hatanaka K, Tasaki T, Yoshioka T, Ohi Y, Yamada S, Tsutsui M, Umekita Y, Tanimoto A.  Anti-apoptotic effects of PCP4/PEP19 in human breast cancer cell lines: a novel oncotarget  Oncotarget  2014  5(15):6076-86  PubMed ID: 25153723
16038  Lale SV, R G A, Aravind A, Kumar DS, Koul V.  AS1411 aptamer and folic acid functionalized pH-responsive ATRP fabricated pPEGMA-PCL-pPEGMA polymeric nanoparticles for targeted drug delivery in cancer therapy  Biomacromolecules  2014  15(5):1737-5  PubMed ID: 24689987
6068  Kariya A, Tabuchi Y, Yunoki T, Kondo T.  Identification of common gene networks responsive to mild hyperthermia in human cancer cells.  Int J Mol Med  2013  32(1):195-202  PubMed ID: 23632739
4391  Takao M, Nagai Y, Torii T.  Cysteine-poor region-specific EpCAM monoclonal antibody recognizing native tumor cells with high sensitivity.  Monoclon Antib Immunodiagn Immunother  2013  32(2):73-80  PubMed ID: 23607341
13656  Kazuaki Ninomiya et al  Evaluation of extra- and intracellular OH radical generation, cancer cell injury, and apoptosis induced by a non-thermal atmospheric-pressure plasma jet  Journal of Physics D: Applied Physics  2013  46:425401 
15767  Maizatul Akmal Yahayu, Mawardi Rahmani, Najihah Mohd Hashim, Gwendoline Cheng Lian Ee, Mohd Aspollah Sukari, Abdah Md Akim  CYTOTOXIC AND ANTIMICROBIAL XANTHONES FROM Cratoxylum arborescens (Guttiferae)  Malaysian Journal of Science  2013  32:53-60 
15780  Ito Y, Mitani T, Harada N, Isayama A, Tanimori S, Takenaka S, Nakano Y, Inui H, Yamaji R.  Identification of carbonyl reductase 1 as a resveratrol-binding protein by affinity chromatography using 4'-amino-3,5-dihydroxy-trans-stilbene  J Nutr Sci Vitaminol (Tokyo)  2013  59(4):358-64  PubMed ID: 24064738
15794  Matsumoto J, Ariyoshi N, Ishii I, Kitada M.  Functional characterization of seven single-nucleotide polymorphisms of the steroid sulfatase gene found in a Japanese population  J Hum Genet  2013  58(5):267-72  PubMed ID: 23466819
15925  Takahashi K, Orba Y, Kimura T, Wang L, Kohsaka S, Tsuda M, Tanino M, Nishihara H, Nagashima K, Sawa H, Tanaka S.  Relationship between methyl CpG binding protein 2 and JC viral proteins  Jpn J Infect Dis  2013  66(2):126-32.  PubMed ID: 23514909
15931  Athulya Aravind, Remya Nair, Sreejith Raveendran, Srivani Veeranarayanan, Yutaka Nagaoka, Takahiro Fukuda, Takahashi Hasumura, Hisao Morimoto, Yasuhiko Yoshida, Toru Maekawa, D. Sakthi Kumar  Aptamer conjugated paclitaxel and magnetic fluid loaded fluorescently tagged PLGA nanoparticles for targeted cancer therapy  Journal of Magnetism and Magnetic Materials  2013  344:116-123 
15947  Tripathi DN, Chowdhury R, Trudel LJ, Tee AR, Slack RS, Walker CL, Wogan GN.  Reactive nitrogen species regulate autophagy through ATM-AMPK-TSC2-mediated suppression of mTORC1  Proc Natl Acad Sci U S A  2013  110(32):E2950-7  PubMed ID: 23878245
15983  Imura Y, Yoshimura E, Sato K.  Microcirculation system with a dialysis part for bioassays evaluating anticancer activity and retention.  Anal Chem  2013  85:1683-8 
16300  Baiyao Xu, Yang Ju, Guanbin Song, Yanbin Cui  tLyP-1-conjugated mesoporous silica nanoparticles for tumor targeting and penetrating hydrophobic drug delivery  Journal of Nanoparticle Research  2013  15 
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