利用者成果(英) |
14519
Kudo M, Anam MB, Istiaq A, Ahmad SAI, Ito N, Ohta K.
Ribosome Incorporation Induces EMT-like Phenomenon with Cell Cycle Arrest in Human Breast Cancer Cell
Cells Tissues Organs
2022
1-10
PubMed ID: 33640894
|
15439
Shams R, Matsukawa A, Ochi Y, Ito Y, Miyatake H.
In Silico and In Cell Hybrid Selection of Nonrapalog Ligands to Allosterically Inhibit the Kinase Activity of mTORC1
J Med Chem
2022
Jun 30
PubMed ID: 34191518
|
15952
Kawahara R, Simizu S.
ErbB4-mediated regulation of vasculogenic mimicry capability in breast cancer cells
Cancer Sci
2022
2021 Dec 31
PubMed ID: 34971015
|
20613
Shimmyo N, Furuhata M, Yamada M, Utoh R, Seki M.
Process simplification and structure design of parallelized microslit isolator for physical property-based capture of tumor cells.
Analyst
2022
PubMed ID: 35297918
|
16497
Toshie Tanaka, Kohei Sano, Mamia Munemura, Masayori Hagimori, Rioh Moriyama, Azusa Yamamoto, Kei-ichi Ozaki, Masayuki Munekane, Toshihide Yamasaki, Takahiro Mukai
A radiolabeled nanoparticle probe coated with hyaluronic acid via electrostatic interaction to diagnose CD44-positive tumors
Journal of Drug Delivery Science and Technology
2022
103473
|
20752
Shindo S, Shioya A, Watanabe M, Sasaki T, Suzuki H, Kumagai T, Hwang GW, Nagata K.
Development of an adenovirus-mediated reporter assay system to detect a low concentration of retinoic acid in MCF-7 cells.
J Toxicol Sci
2022
47(6):249-255
PubMed ID: 35650141
|
16737
Yusuke Takizawa, Junya Oguri, Masaya Uno, Ami Onsui, Atsushi Ishimura, Takuro Kurita, Takanori Nakajima
Effects of A GLP‑1 Receptor Agonist on Gastrointestinal Epithelial Cells
Scholars Academic Journal of Pharmacy
2022
11:60-66
|
16741
Isaac Kingsley Amponsah, Gina Flor Ramos, Benjamin Kingsley Harley, Joseph Adusei Sarkodie, Edmund Ekuadzi, Elikplim Kwesi Ampofo, Inemesit Okon Ben
Anti-inflammatory, Antioxidant and Cytotoxic Activities of Guibourtia ehie on Human Prostate (PC-3) and Breast Cancer (MC-7) Cell Lines and in silico Studies on Its Metabolite 7,4′-Dihydroxyflavone
Chemistry Africa
2022
5:627-639
|
20799
Fujimoto M, Takii R, Matsumoto M, Okada M, Nakayama KI, Nakato R, Fujiki K, Shirahige K, Nakai A.
HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.
Nat Commun
2022
13(1):4355
PubMed ID: 35906200
|
12852
Kawai T, Mihara Y, Morita M, Ohkubo M, Asami T, Watanabe TM.
Quantitation of Cell Membrane Permeability of Cyclic Peptides by Single-Cell Cytoplasm Mass Spectrometry
Anal Chem
2021
PubMed ID: 33550808
|
13361
Luo F, Sugita H, Muraki K, Saeki S, Chaipech S, Pongpiriyadacha Y, Muraoka O, Morikawa T.
Anti-proliferative activities of coumarins from the Thai medicinal plant Mammea siamensis (Miq.) T. Anders. against human digestive tract carcinoma cell lines.
Fitoterapia
2021
PubMed ID: 33246033
|
13416
Sagara M, Miyamoto S, Itoh S, Soda Y, Tani K.
Development of New Oncolytic Virotherapy Targeting Breast Cancer Using Coxsackievirus B3.
Anticancer Res
2021
PubMed ID: 33419801
|
20159
Sakabe T, Wakahara M, Shiota G, Umekita Y.
Role of cytoplasmic localization of maspin in promoting cell invasion in breast cancer with aggressive phenotype.
Sci Rep
2021
11(1):11321
PubMed ID: 34059749
|
15503
Takeo Takeda, Masahiro Ogawa, Junya Kitamoto, Takahiro Kyoya, Megumi Terada
High Glucose Enhances Skin Sensitizer-induced NRF2 Activation In Vitro
The Open Toxicology Journal
2021
7:8-17
|
15518
Kawasaki Y, Sendo T.
Three photoinitiators induce breast tumor growth in mouse xenografts with MCF-7 breast cancer cells
Curr Res Toxicol
2021
2:322-328
PubMed ID: 34522900
|
20360
Kashio-Yokota Y, Sato S, Hirose T, Watanabe T, Endo A, Watanabe F, Endo M, Ohba K, Mori T, Takahashi K.
Elevated (Pro)renin Receptor Expression by Anti-Cancer Drugs, Carboplatin and Paclitaxel, in Cultured Cancer Cells: Possible Involvement of Apoptosis and Autophagy.
Tohoku J Exp Med
2021
255(2):91-104
PubMed ID: 34645770
|
20379
Imashiro C, Takeshita H, Morikura T, Miyata S, Takemura K, Komotori J.
Development of accurate temperature regulation culture system with metallic culture vessel demonstrates different thermal cytotoxicity in cancer and normal cells.
Sci Rep
2021
11(1):21466
PubMed ID: 34728686
|
20392
Shikata M, Toyooka T, Komaki Y, Ibuki Y.
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone-Induced Histone Acetylation via α7nAChR-Mediated PI3K/Akt Activation and Its Impact on γ-H2AX Generation.
Chem Res Toxicol
2021
PubMed ID: 34784199
|
20401
Oda Y, Takahashi C, Harada S, Nakamura S, Sun D, Kiso K, Urata Y, Miyachi H, Fujiyoshi Y, Honigmann A, Uchida S, Ishihama Y, Toyoshima F.
Discovery of anti-inflammatory physiological peptides that promote tissue repair by reinforcing epithelial barrier formation.
Sci Adv
2021
7(47):eabj6895
PubMed ID: 34788088
|
20406
Sawa C, Yofu S, Kiriyama K, Sutoh K, Saito T, Kishi S, Gunji M, Inoue Y, Sugi M, Shioda S, Honda K.
High concentration of extracellular nucleotides suppresses cell growth via delayed cell cycle progression in cancer and noncancer cell lines.
Heliyon
2021
7(11):e08318
PubMed ID: 34816032
|
20434
Chia JY, Miki T, Mihara H, Tsutsumi H.
Biofunctional supramolecular hydrogels fabricated from a short self-assembling peptide modified with bioactive sequences for the 3D culture of breast cancer MCF-7 cells.
Bioorg Med Chem
2021
46:116345
PubMed ID: 34416510
|
16102
Arung ET, Ramadhan R, Khairunnisa B, Amen Y, Matsumoto M, Nagata M, Kusuma IW, Paramita S, Sukemi, Yadi, Tandirogang N, Takemoto N, Syafrizal, Kim YU, Shimizu K.
Cytotoxicity effect of honey, bee pollen, and propolis from seven stingless bees in some cancer cell lines
Saudi J Biol Sci
2021
;28(12):7182-7189
PubMed ID: 34867021
|
16111
Ii H, Nohara Y, Yoshiya T, Masuda S, Tsuda S, Oishi S, Friedman J, Kawabe T, Nakata S.
Identification of U83836E as a γ-glutamylcyclotransferase inhibitor that suppresses MCF7 breast cancer xenograft growth
Biochem Biophys Res Commun
2021
549:128-134
PubMed ID: 33676180
|
16372
Yoshitaka Koseki, Yoshikazu Ikuta, Farsai Taemaitree, Nozomi Saito, Ryuju Suzuki, Anh Thi Ngoc Dao, Tsunenobu Onodera, Hidetoshi Oikawa, Hitoshi Kasai
Fabrication of size-controlled SN-38 pure drug nanocrystals through an ultrasound-assisted reprecipitation method toward efficient drug delivery for cancer treatment
Journal of Crystal Growth
2021
572:126265
|
16522
Kawatani M, Aono H, Hiranuma S, Shimizu T, Muroi M, Ogawa N, Ohishi T, Ohba SI, Kawada M, Nogawa T, Okano A, Hashizume D, Osada H.
Identification of a Small-Molecule Glucose Transporter Inhibitor, Glutipyran, That Inhibits Cancer Cell Growth
ACS Chem Biol
2021
16(8):1576-1586
PubMed ID: 34296611
|
16701
Chinen T, Yamazaki K, Hashimoto K, Fujii K, Watanabe K, Takeda Y, Yamamoto S, Nozaki Y, Tsuchiya Y, Takao D, Kitagawa D.
Centriole and PCM cooperatively recruit CEP192 to spindle poles to promote bipolar spindle assembly
J Cell Biol
2021
220(2):e202006085
PubMed ID: 33443571
|
16728
YUSUF LIMBONGAN, RICO RAMADHAN, KUNIYOSHI SHIMIZU, Enos Tangkearung
Agronomic characteristics of 30 promising lines of aromatic, red, and black rice and their antioxidant and cytotoxic effects in some cancer cells
Biodiversitas Journal of Biological Diversity
2021
|
16735
Okada H, Mimura M, Tomita S, Kurita R.
Affinity Diversification of a Polymer Probe for Pattern-recognition-based Biosensing Using Chemical Additives
Anal Sci
2021
37(5):713-719
PubMed ID: 33518589
|
6048
Nashimoto Y, Okada R, Hanada S, Arima Y, Nishiyama K, Miura T, Yokokawa R.
Vascularized cancer on a chip: The effect of perfusion on growth and drug delivery of tumor spheroid.
Biomaterials
2020
229:119547
PubMed ID: 31710953
|
6885
Asano M, Tanaka S, Sakaguchi M.
Effects of normothermic microwave irradiation on CD44+/CD24‒ in breast cancer MDA-MB-231 and MCF-7 cell lines.
Biosci Biotechnol Biochem.
2020
84(1):103-110
PubMed ID: 31559912
|
6905
Toda H, Seki N, Kurozumi S, Shinden Y, Yamada Y, Nohata N, Moriya S, Idichi T, Maemura K, Fujii T, Horiguchi J, Kijima Y, Natsugoe S.
RNA-sequence-based microRNA expression signature in breast cancer: tumor-suppressive miR-101-5p regulates molecular pathogenesis.
Mol Oncol
2020
14(2):426-446
PubMed ID: 31755218
|
6932
Yeong KY, Khaw KY, Takahashi Y, Itoh Y, Murugaiyah V, Suzuki T.
Discovery of gamma-mangostin from Garcinia mangostana as a potent and selective natural SIRT2 inhibitor.
Bioorg Chem
2020
94:103403
PubMed ID: 31711765
|
10147
Mohamed O Radwan, Halil I Ciftci, Taha F S Ali, Ryoko Koga, Hiroshi Tateishi, Akiko Nakata, Akihiro Ito, Minoru Yoshida, Mikako Fujita, Masami Otsuka
Structure activity study of S-trityl-cysteamine dimethylaminopyridine derivatives as SIRT2 inhibitors: Improvement of SIRT2 binding and inhibition
Bioorg Med Chem Lett
2020
30(19):127458
PubMed ID: 32755678
|
11920
Takumi Chinen , Shohei Yamamoto, Yutaka Takeda , Koki Watanabe, Kanako Kuroki , Kaho Hashimoto , Daisuke Takao , Daiju Kitagawa
NuMA assemblies organize microtubule asters to establish spindle bipolarity in acentrosomal human cells
EMBO J
2020
PubMed ID: 31782546
|
12004
Borah A, Pillai SC, Rochani AK, Palaninathan V, Nakajima Y, Maekawa T, Kumar DS.
GANT61 and curcumin-loaded PLGA nanoparticles for GLI1 and PI3K/Akt-mediated inhibition in breast adenocarcinoma.
Nanotechnology
2020
PubMed ID: 31952056
|
12047
Dadzie I, Avorgbedo SA, Appiah-Opong R, Cudjoe O.
Cytotoxic and Antioxidant Effects of Antimalarial Herbal Mixtures.
Int J Microbiol
2020
PubMed ID: 32104181
|
12054
Takeda K, Kawamoto Y, Nagasaki Y, Okuno Y, Goto Y, Iida M, Yajima I, Ohgami N, Kato M.
Peptides containing the MXXCW motif inhibit oncogenic RET kinase activity with a novel mechanism of action.
Am J Cancer Res
2020
PubMed ID: 32064171
|
12100
Okubo S, Ohta T, Shoyama Y, Uto T.
Arctigenin suppresses cell proliferation via autophagy inhibition in hepatocellular carcinoma cells.
J Nat Med
2020
PubMed ID: 32207025
|
12136
Choodej, Khanitha Pudhom
Cycloartane triterpenoids from the leaves of Euphorbia neriifolia
Phytochemistry Letters
2020
|
12149
Kruthi Suvarna, Kaori Honda, Makoto Muroi, Yasumitsu Kondoh, Nobumoto Watanabe, Hiroyuki Osada
Identification of Target Protein for Bio-active Small Molecule Using Photo-cross Linked Beads and MALDI-TOF Mass Spectrometry
Bio Protoc
2020
10
|
10510
Kenward Vong, Tomoya Yamamoto, Tsung-che Changa and Katsunori Tanaka
Bioorthogonal release of anticancer drugs via gold-triggered 2-alkynylbenzamide cyclization
Chemical Science
2020
11:10928-10933
|
12989
Endo M, Ohba K, Sato S, Yokota Y, Takahashi K.
Increased soluble (pro)renin receptor protein by autophagy inhibition in cultured cancer cells.
Genes Cells
2020
PubMed ID: 32314441
|
13051
Sakaguchi M, Kitaguchi D, Morinami S, Kurashiki Y, Hashida H, Miyata S, Yamaguchi M, Sakai M, Murata N, Tanaka S.
Berberine-induced nucleolar stress response in a human breast cancer cell line.
Biochem Biophys Res Commun
2020
PubMed ID: 32475643
|
13095
Mai NNH, Yamaguchi Y, Choijookhuu N, Matsumoto J, Nanashima A, Takagi H, Sato K, Tuan LQ, Hishikawa Y.
Photodynamic Therapy Using a Novel Phosphorus Tetraphenylporphyrin Induces an Anticancer Effect via Bax/Bcl-xL-related Mitochondrial Apoptosis in Biliary Cancer Cells.
Acta Histochem Cytochem
2020
PubMed ID: 32873990
|
13270
Kiyomi A, Miyakawa R, Matsumoto J, Yamazaki K, Imai S, Yuan B, Hirano T, Sugiura M.
Potent antitumor activity of cepharanthine against triple-negative breast cancer spheroids compared with tetrandrine.
Oncol Lett
2020
PubMed ID: 33101499
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13317
Fujita K, Kamiya M, Yoshioka T, Ogasawara A, Hino R, Kojima R, Ueo H, Urano Y.
Rapid and Accurate Visualization of Breast Tumors with a Fluorescent Probe Targeting α-Mannosidase 2C1.
ACS Cent Sci
2020
PubMed ID: 33376783
|
13585
Tottori N, Nisisako T.
Particle/cell separation using sheath-free deterministic lateral displacement arrays with inertially focused single straight input
Lab Chip
2020
20(11):1999-2008
PubMed ID: 32373868
|
13593
Ciftci HI, Can M, Ellakwa DE, Suner SC, Ibrahim MA, Oral A, Sekeroglu N, Özalp B, Otsuka M, Fujita M, Alparslan M, Radwan MO.
Anticancer activity of Turkish marine extracts: a purple sponge extract induces apoptosis with multitarget kinase inhibition activity
Invest New Drugs
2020
38(5):1326-1333
PubMed ID: 32062733
|
13595
Guo W, Mashimo Y, Kobatake E, Mie M.
Construction of DNA-displaying nanoparticles by enzymatic conjugation of DNA and elastin-like polypeptides using a replication initiation protein
Nanotechnology
2020
31(25):255102
PubMed ID: 32176872
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14364
Kohzaki M, Ootsuyama A, Sun L, Moritake T, Okazaki R.
Human RECQL4 represses the RAD52-mediated single-strand annealing pathway after ionizing radiation or cisplatin treatment
Int J Cancer
2020
146(11):3098-3113
PubMed ID: 31495919
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14854
Terasaki A, Kurokawa H, Ito H, Komatsu Y, Matano D, Terasaki M, Bando H, Hara H, Matsui H.
Elevated Production of Mitochondrial Reactive Oxygen Species via Hyperthermia Enhanced Cytotoxic Effect of Doxorubicin in Human Breast Cancer Cell Lines MDA-MB-453 and MCF-7
Int J Mol Sci
2020
21(24):9522
PubMed ID: 33333736
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11195
Okahashi N, Maeda K, Kawana S, Iida J, Shimizu H, Matsuda F.
Sugar phosphate analysis with baseline separation and soft ionization by gas chromatography-negative chemical ionization-mass spectrometry improves flux estimation of bidirectional reactions in cancer cells.
Metab. Eng
2019
51:43-49
PubMed ID: 30176394
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4053
Ali TFS, Ciftci HI, Radwan MO, Koga R, Ohsugi T, Okiyama Y, Honma T, Nakata A, Ito A, Yoshida M, Fujita M, Otsuka M.
New SIRT2 inhibitors: Histidine-based bleomycin spin-off
Bioorg Med Chem
2019
27:1767-1775
PubMed ID: 30885568
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11297
Mie M, Matsumoto R, Mashimo Y, Cass AEG, Kobatake E.
Development of drug-loaded protein nanoparticles displaying enzymatically-conjugated DNA aptamers for cancer cell targeting.
Mol. Biol. Rep.
2019
PubMed ID: 30421127
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11308
Imamura T, Isozumi N, Higashimura Y, Miyazato A, Mizukoshi H, Ohki S, Mori M.
Isolation of amaranthin synthetase from Chenopodium quinoa and construction of an amaranthin production system using suspension-cultured tobacco BY-2 cells.
Plant Biotechnol. J.
2019
PubMed ID: 30451369
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11360
Futami K, Kimoto M, Lim YWS, Hirao I.
Genetic Alphabet Expansion Provides Versatile Specificities and Activities of Unnatural-Base DNA Aptamers Targeting Cancer Cells.
Mol Ther Nucleic Acids
2019
PubMed ID: 30594072
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11324
Lin Y, Chen Y, Ukaji T, Okada S, Umezawa K.
Isolation of ketomycin from Actinomycetes as an inhibitor of 2D and 3D cancer cell invasion.
J. Antibiot.
2019
PubMed ID: 30510246
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11375
Handa T, Katayama A, Yokobori T, Yamane A, Fujii T, Obayashi S, Kurozumi S, Kawabata-Iwakawa R, Gombodorj N, Nishiyama M, Asao T, Shirabe K, Kuwano H, Oyama T.
Carboxypeptidase A4 accumulation is associated with an aggressive phenotype and poor prognosis in triple-negative breast cancer.
Int. J. Oncol.
2019
PubMed ID: 30628666
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11381
Win NN, Kyaw MM, Prema, Ngwe H, Ito T, Asakawa Y, Okamoto Y, Tanaka M, Abe I, Morita H.
Dinorcassane Diterpenoid from Boesenbergia rotunda Rhizomes Collected in Lower Myanmar.
Chem. Biodivers.
2019
PubMed ID: 30645035
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11472
Suzuki S, Fukuda T, Nagayasu S, Nakanishi J, Yoshida K, Hirata-Tsuchiya S, Nakao Y, Sano T, Yamashita A, Yamada S, Ohta K, Shiba H, Nishimura F.
Dental pulp cell-derived powerful inducer of TNF-α comprises PKR containing stress granule rich microvesicles.
Sci Rep
2019
PubMed ID: 30846715
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4759
Halil I. Ciftci, Mohamed O. Radwan, Safiye E. Ozturk, N. Gokce Ulusoy, Ece Sozer, Doha E. Ellakwa, Zeynep Ocak, Mustafa Can, Taha F.S. Ali, Howaida I. Abd-Alla, Nurettin Yayli, Hiroshi Tateishi, Masami Otsuka and Mikako Fujita
Design, Synthesis and Biological Evaluation of Pentacyclic Triterpene Derivatives: Optimization of Anti-ABL Kinase Activity
Molecules
2019
24:3535
PubMed ID: 31574910
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4760
Mohamed O. Radwan, Halil I. Ciftci, Taha F. S. Ali , Doha E. Ellakwa, Ryoko Koga, Hiroshi Tateishi, Akiko Nakata, Akihiro Ito, Minoru Yoshida, Yoshinari Okamoto, Mikako Fujita and Masami Otsuka
Antiproliferative S-Trityl-l-Cysteine -Derived Compounds as SIRT2 Inhibitors: Repurposing and Solubility Enhancement
Molecules
2019
24:3295
PubMed ID: 31510043
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11611
Takahashi T, Honsho M, Abe Y, Fujiki Y.
Plasmalogen mediates integration of adherens junction.
J. Biochem.
2019
PubMed ID: 31236591
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11724
Othman DIA, Selim KB, El-Sayed MA, Tantawy AS, Amen Y, Shimizu K, Okauchi T, Kitamura M.
Design, Synthesis and Anticancer Evaluation of New Substituted Thiophene-Quinoline Derivatives.
Bioorg. Med. Chem.
2019
PubMed ID: 31416740
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11851
Fujitani N, Yoneda A, Takahashi M, Takasawa A, Aoyama T, Miyazaki T.
Silencing of Glutathione S-Transferase Pi Inhibits Cancer Cell Growth via Oxidative Stress Induced by Mitochondria Dysfunction.
Sci Rep
2019
PubMed ID: 31611630
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11864
Matsumoto Y, Kuriki H, Kitamura T, Takahashi D, Toshima K.
Total Synthesis and Structure-Activity Relationship Study of Vineomycin A1.
J. Org. Chem.
2019
PubMed ID: 31642324
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6837
Bouallagui Z, Mahmoudi A, Maalej A, Hadrich F, Isoda H, Sayadi S.
Contribution of Major Polyphenols to the Antioxidant Profile and Cytotoxic Activity of Olive Leaves.
Anticancer Agents Med Chem
2019
19(13):1651-1657
PubMed ID: 31038081
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6942
Mahmoud Abdel-Hamid et al
The biological activity of fermented milk produced by Lactobacillus casei ATCC 393 during cold storage
International Dairy Journal
2019
91:1-8
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9810
Junko Shibato, Fumiko Takenoya, Takahiro Hirabayashi, Ai Kimura, Yusuke Iwasaki, Yoko Toyoda, Motohide Hori, Shigeru Tamogami, Randeep Rakwal, Seiji Shioda
Towards Identification of Bioactive Compounds in Cold Vacuum Extracted Double Cherry Blossom (Gosen-Sakura) Leaves
Plant Signal Behav
2019
14(10):e1644594
PubMed ID: 31342859
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10468
R. SowmiyaTanakorn OsotchanDakrong Pissuwan
The Impact of Gold Nanoparticles with Low Energy Irradiation Treatment on Temperature Induction and Cell Viability of Breast Cancer Cell
International Conference on Nanomedicine
2019
86-93
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10357
Belgin Sever, Mehlika Dilek Altıntop, Mohamed O Radwan, Ahmet Özdemir, Masami Otsuka, Mikako Fujita, Halil I Ciftci
Design, synthesis and biological evaluation of a new series of thiazolyl-pyrazolines as dual EGFR and HER2 inhibitors
Eur J Med Chem
2019
82:111648
PubMed ID: 31493743
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12517
Satria D, Amen Y, Niwa Y, Ashour A, Allam AE, Shimizu K.
Lucidumol D, a new lanostane-type triterpene from fruiting bodies of Reishi (Ganoderma lingzhi)
Nat Prod Res
2019
33(2):189-195
PubMed ID: 29457741
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12559
Li F, Kitajima S, Kohno S, Yoshida A, Tange S, Sasaki S, Okada N, Nishimoto Y, Muranaka H, Nagatani N, Suzuki M, Masuda S, Thai TC, Nishiuchi T, Tanaka T, Barbie DA, Mukaida N, Takahashi C.
Retinoblastoma Inactivation Induces a Protumoral Microenvironment via Enhanced CCL2 Secretion
Cancer Res
2019
79(15):3903-3915
PubMed ID: 31189648
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12958
Yu B, Yuan B, Kiyomi A, Kikuchi H, Hayashi H, Hu X, Okazaki M, Sugiura M, Hirano T, Pei X, Takagi N.
Differentiation induction of human breast cancer cells by arsenite in combination with tetrandrine.
Am J Transl Res
2019
PubMed ID: 31934280
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9501
Shiota M, Naya M, Yamamoto T, Hishiki T, Tani T, Takahashi H, Kubo A, Koike D, Itoh M, Ohmura M, Kabe Y, Sugiura Y, Hiraoka N, Morikawa T, Takubo K, Suina K, Nagashima H, Sampetrean O, Nagano O, Saya H, Yamazoe S, Watanabe H, Suematsu M.
Gold-nanofève surface-enhanced Raman spectroscopy visualizes hypotaurine as a robust anti-oxidant consumed in cancer survival.
Nat Commun
2018
9:1561
PubMed ID: 29674746
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10700
Taniguchi K, Matsumura K, Kageyama S, Ii H, Ashihara E, Chano T, Kawauchi A, Yoshiki T, Nakata S.
Prohibitin-2 is a novel regulator of p21WAF1/CIP1 induced by depletion of γ-glutamylcyclotransferase.
Biochem. Biophys. Res. Commun.
2018
496:218-224
PubMed ID: 29307834
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10706
Bao H, Bai T, Takata K, Yokobori T, Ohnaga T, Hisada T, Maeno T, Bao P, Yoshida T, Kumakura Y, Honjo H, Sakai M, Sohda M, Fukuchi M, Altan B, Handa T, Ide M, Miyazaki T, Ogata K, Oyama T, Shimizu K, Mogi A, Asao T, Shirabe K, Kuwano H, Kaira K.
High expression of carcinoembryonic antigen and telomerase reverse transcriptase in circulating tumor cells is associated with poor clinical response to the immune checkpoint inhibitor nivolumab.
Oncol Lett
2018
15:3061-3067
PubMed ID: 29435038
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10735
Suvarna K, Honda K, Kondoh Y, Osada H, Watanabe N.
Identification of a small-molecule ligand of β-arrestin1 as an inhibitor of stromal fibroblast cell migration accelerated by cancer cells.
Cancer Med
2018
7:883-893
PubMed ID: 29380537
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10760
Oo PS, Yamaguchi Y, Sawaguchi A, Tin Htwe Kyaw M, Choijookhuu N, Noor Ali M, Srisowanna N, Hino SI, Hishikawa Y.
Estrogen Regulates Mitochondrial Morphology through Phosphorylation of Dynamin-related Protein 1 in MCF7 Human Breast Cancer Cells.
Acta Histochem Cytochem
2018
51:21-31
PubMed ID: 29622847
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10845
Taniguchi K, Matsumura K, Ii H, Kageyama S, Ashihara E, Chano T, Kawauchi A, Yoshiki T, Nakata S.
Depletion of gamma-glutamylcyclotransferase in cancer cells induces autophagy followed by cellular senescence.
Am J Cancer Res
2018
8:650-661
PubMed ID: 29736310
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11113
Kawai T, Ota N, Imasato A, Shirasaki Y, Otsuka K, Tanaka Y.
Profiling of N-linked glycans from 100 cells by capillary electrophoresis with large-volume dual preconcentration by isotachophoresis and stacking.
J Chromatogr A
2018
1565:138-144
PubMed ID: 29945790
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11160
Languon S, Tuffour I, Quayson EE, Appiah-Opong R, Quaye O.
In Vitro Evaluation of Cytotoxic Activities of Marketed Herbal Products in Ghana.
J Evid Based Integr Med
2018
PubMed ID: 30088418
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11164
Mogi K, Hayashida K, Yamamoto T.
Damage-less Handling of Exosomes Using an Ion-depletion Zone in a Microchannel.
Anal Sci
2018
34(8):875-880
PubMed ID: 30101880
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4421
Mohamed S. Mohamed et al
Ultra-Low Power NIR Laser-Triggered Phototherapy and μCT Imaging of Breast Cancer In Vivo
IEEE Xplore
2018
14 February
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4422
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Journal of the Indian Academy of Wood Science
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Acta Biomater
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Front Physiol
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Fitoterapia
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Enjoji S, Yabe R, Tsuji S, Yoshimura K, Kawasaki H, Sakurai M, Sakai Y, Takenouchi H, Yoshino S, Hazama S, Nagano H, Oshima H, Oshima M, Vitek MP, Matsuura T, Hippo Y, Usui T, Ohama T, Sato K.
Stemness Is Enhanced in Gastric Cancer by a SET/PP2A/E2F1 Axis
Mol Cancer Res
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The HSF1-PARP13-PARP1 complex facilitates DNA repair and promotes mammary tumorigenesis.
Nat Commun
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The prolyl oligopeptidase inhibitor SUAM-14746 attenuates the proliferation of human breast cancer cell lines in vitro.
Breast Cancer
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Tatebe H, Murayama S, Yonekura T, Hatano T, Richter D, Furuya T, Kataoka S, Furuita K, Kojima C, Shiozaki K.
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Elife
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Kitajima S, Yoshida A, Kohno S, Li F, Suzuki S, Nagatani N, Nishimoto Y, Sasaki N, Muranaka H, Wan Y, Thai TC, Okahashi N, Matsuda F, Shimizu H, Nishiuchi T, Suzuki Y, Tominaga K, Gotoh N, Suzuki M, Ewen ME, Barbie DA, Hirose O, Tanaka T, Takahashi C.
The RB-IL-6 axis controls self-renewal and endocrine therapy resistance by fine-tuning mitochondrial activity.
Oncogene
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Nashimoto Y, Hayashi T, Kunita I, Nakamasu A, Torisawa YS, Nakayama M, Takigawa-Imamura H, Kotera H, Nishiyama K, Miura T, Yokokawa R.
Integrating perfusable vascular networks with a three-dimensional tissue in a microfluidic device.
Integr Biol (Camb)
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Kawabata H, Azuma K, Ikeda K, Sugitani I, Kinowaki K, Fujii T, Osaki A, Saeki T, Horie-Inoue K, Inoue S.
TRIM44 Is a Poor Prognostic Factor for Breast Cancer Patients as a Modulator of NF-κB Signaling.
Int J Mol Sci
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Potent mechanism-based sirtuin-2-selective inhibition by an in situ-generated occupant of the substrate-binding site, "selectivity pocket" and NAD+-binding site.
Chem Sci
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Ankita Borah, Vivekanandan Palaninathan, Aswathy Ravindran Girija, Sivakumar Balasubramanian, Ankit K. Rochani, Toru Maekawa and D. Sakthi Kumar
Poly-lactic-co-glycolic acid Nanoformulation of Small Molecule Antagonist GANT61 for Cancer Annihilation by Modulating Hedgehog Pathway
NanoWorld Journal
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Engineering a three-dimensional tissue model with a perfusable vasculature in a microfluidic device
IEEE Xplore
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Takasugi M, Okada R, Takahashi A, Virya Chen D, Watanabe S, Hara E.
Small extracellular vesicles secreted from senescent cells promote cancer cell proliferation through EphA2.
Nat Commun
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Handa T, Katayama A, Yokobori T, Yamane A, Horiguchi J, Kawabata-Iwakawa R, Rokudai S, Bao P, Gombodorj N, Altan B, Kaira K, Asao T, Kuwano H, Nishiyama M, Oyama T.
Caspase14 expression is associated with triple negative phenotypes and cancer stem cell marker expression in breast cancer patients
J Surg Oncol
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Miyasato Y, Shiota T, Ohnishi K, Pan C, Yano H, Horlad H, Yamamoto Y, Yamamoto-Ibusuki M, Iwase H, Takeya M, Komohara Y.
High density of CD204-positive macrophages predicts worse clinical prognosis in patients with breast cancer
Cancer Sci
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108(8):1693-1700
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Shiraishi A, Tachi K, Essid N, Tsuboi I, Nagano M, Kato T, Yamashita T, Bando H, Hara H, Ohneda O.
Hypoxia promotes the phenotypic change of aldehyde dehydrogenase activity of breast cancer stem cells
Cancer Sci
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108(3):362-372
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Yoshida A, Kitajima S, Li F, Cheng C, Takegami Y, Kohno S, Wan YS, Hayashi N, Muranaka H, Nishimoto Y, Nagatani N, Nishiuchi T, Thai TC, Suzuki S, Nakao S, Tanaka T, Hirose O, Barbie DA, Takahashi C.
MicroRNA-140 mediates RB tumor suppressor function to control stem cell-like activity through interleukin-6
Oncotarget
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8(8):13872-13885
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Hayashi K, Sato Y, Sakamoto W, Yogo T.
Theranostic Nanoparticles for MRI-Guided Thermochemotherapy: "Tight" Clustering of Magnetic Nanoparticles Bo
ACS Biomater Sci Eng
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3(1):95-105
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Yamauchi I, Sakane Y, Fukuda Y, Fujii T, Taura D, Hirata M, Hirota K, Ueda Y, Kanai Y, Yamashita Y, Kondo E, Sone M, Yasoda A, Inagaki N.
Clinical Features of Nivolumab-Induced Thyroiditis: A Case Series Study
Thyroid
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27(7):894-901
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Ninomiya K, Maruyama H, Ogino C, Takahashi K, Shimizu N.
Sonocatalytic injury of cancer cells attached on the surface of a nickel-titanium dioxide alloy plate.
Ultrason Sonochem
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28:1-6
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Ninomiya K, Yamashita T, Tanabe Y, Imai M, Takahashi K, Shimizu N.
Targeted and ultrasound-triggered cancer cell injury using perfluorocarbon emulsion-loaded liposomes endowed with cancer cell-targeting and fusogenic capabilities.
Ultrason Sonochem
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28:54-61
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Sasaki S, Kanzaki M, Kaneko T.
Calcium influx through TRP channels induced by short-lived reactive species in plasma-irradiated solution.
Sci Rep
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Kanzaki H, Shinohara F, Suzuki M, Wada S, Miyamoto Y, Yamaguchi Y, Katsumata Y, Makihira S, Kawai T, Taubman MA, Nakamura Y.
A-Disintegrin and Metalloproteinase (ADAM) 17 Enzymatically Degrades Interferon-gamma.
Sci Rep
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Yanagawa T, Denda K, Inatani T, Fukushima T, Tanaka T, Kumaki N, Inagaki Y, Komada M.
Deficiency of X-Linked Protein Kinase Nrk during Pregnancy Triggers Breast Tumor in Mice.
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Tanaka S, Sakaguchi M, Yoneyama H, Usami Y, Harusawa S.
Histamine H3 receptor antagonist OUP-186 attenuates the proliferation of cultured human breast cancer cell lines.
Biochem. Biophys. Res. Commun.
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Poulose AC, Veeranarayanan S, Mohamed MS, Aburto RR, Mitcham T, Bouchard RR, Ajayan PM, Sakamoto Y, Maekawa T, Kumar DS.
Multifunctional Cu2-xTe Nanocubes Mediated Combination Therapy for Multi-Drug Resistant MDA MB 453.
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Down-Regulation of Ca2+-Activated K⁺ Channel KCa1.1 in Human Breast Cancer MDA-MB-453 Cells Treated with Vitamin D Receptor Agonists.
Int J Mol Sci
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Matsumura K, Nakata S, Taniguchi K, Ii H, Ashihara E, Kageyama S, Kawauchi A, Yoshiki T.
Depletion of γ-glutamylcyclotransferase inhibits breast cancer cell growth via cellular senescence induction mediated by CDK inhibitor upregulation.
BMC Cancer
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Targeting CD44, ABCG2 and CD133 markers using aptamers: in silico analysis of CD133 extracellular domain 2 and its aptamer
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Development of an ‘OFF-ON-OFF’ fluorescent pH sensor suitable for the study of intracellular pH
Tetrahedron
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Extracts of Codiaeum variegatum (L.) A. Juss is Cytotoxic on Human Leukemic, Breast and Prostate Cancer Cell Lines
Journal of Applied Pharmaceutical Science
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6, 087-093
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Yosuke Amagai, Tomoko Fujiyuki, Misako Yoneda, Koichiro Shoji, Yoichi Furukawa, Hiroki Sato, Chieko Kai
Oncolytic Activity of a Recombinant Measles Virus, Blind to Signaling Lymphocyte Activation Molecule, Against Colorectal Cancer Cells
Sci Rep
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6, 24572
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Kano H, Takayama T, Midorikawa Y, Nagase H.
Promoter hypomethylation of RAR-related orphan receptor α 1 is correlated with unfavorable clinicopathological features in patients with colorectal cancer
Biosci Trends
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Taira, N., Iwasaki, H., Inafuku, M., Saitoh, S., & Oku, H.
Enhanced cytotoxicity of nitidine against camptothecin‐resistant A549 cells
Traditional & Kampo Medicine
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3(1):33-40
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Kikuchi M, Yamashita K, Waraya M, Minatani N, Ushiku H, Kojo K, Ema A, Kosaka Y, Katoh H, Sengoku N, Enomoto T, Tanino H, Sawanobori M, Watanabe M.
Epigenetic regulation of ZEB1-RAB25/ESRP1 axis plays a critical role in phenylbutyrate treatment-resistant breast cancer
Oncotarget
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PubMed ID: 26646320
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FOXA1 expression affects the proliferation activity of luminal breast cancer stem cell populations
Cancer Sci
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107(3):281-9
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Yoshimura T, Hamada T, Hijioka H, Souda M, Hatanaka K, Yoshioka T, Yamada S, Tsutsui M, Umekita Y, Nakamura N, Tanimoto A.
PCP4/PEP19 promotes migration, invasion and adhesion in human breast cancer MCF-7 and T47D cells
Oncotarget
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7(31):49065-49074
PubMed ID: 27384474
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Kume K, Ikeda M, Miura S, Ito K, Sato KA, Ohmori Y, Endo F, Katagiri H, Ishida K, Ito C, Iwaya T, Nishizuka SS.
α-Amanitin Restrains Cancer Relapse from Drug-Tolerant Cell Subpopulations via TAF15
Sci Rep
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REGINA APPIAH-OPONG, ISAAC KWADWO ASANTE, DORCAS OSEI SAFO, ISAAC TUFFOUR, EBENEZER OFORI- ATTAH, TAKUHIRO UTO, ALEXANDER KWADWO NYARKO
Cytotoxic effects of Albizia zygia (DC) JF Macbr, a Ghanaian medicinal plant, against human T-lymphoblast-like leukemia, prostate and breast cancer cell lines
International Journal of Pharmacy and Pharmaceutical Sciences
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Johmura Y, Sun J, Kitagawa K, Nakanishi K, Kuno T, Naiki-Ito A, Sawada Y, Miyamoto T, Okabe A, Aburatani H, Li S, Miyoshi I, Takahashi S, Kitagawa M, Nakanishi M.
SCF(Fbxo22)-KDM4A targets methylated p53 for degradation and regulates senescence
Nat Commun
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Morizane M, Kawasaki Y, Miura T, Yagi K, Esumi S, Kitamura Y, Sendo T.
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J. Toxicol. Environ. Health Part A
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Nakaoka E, Tanaka S, Onda K, Sugiyama K, Hirano T.
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Zhu Q, Bang TH, Ohnuki K, Sawai T, Sawai K, Shimizu K.
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Sci Rep
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Tomita T, Ieguchi K, Sawamura T, Maru Y.
Human serum amyloid A3 (SAA3) protein, expressed as a fusion protein with SAA2, binds the oxidized low density lipoprotein receptor.
PLoS ONE
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Watari A, Hashegawa M, Muangman T, Yagi K, Kondoh M.
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Subramanian N, Kanwar JR, Athalya PK, Janakiraman N, Khetan V, Kanwar RK, Eluchuri S, Krishnakumar S.
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J Global Biosciences
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Masanari Umemura, Mayumi Katsumata, Itaru Sato, Akane Nagasako, Haruki Aoyama, Ayako Makino, Makoto Ohtake, Kayoko Oda, Kosuke Matsuo, Haruki Eguchi, Yoshihiro Ishikawa
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Jun Matsumoto, Noritaka Ariyoshi, Masahiro Sakakibara, Takeo Nakanishi, Yoshiyuki Okubo, Nobumitsu Shiina, Kaoru Fujisaki, Takeshi Nagashima, Yukio Nakatani, Ikumi Tamai, Harumi Yamada, Hiroshi Takeda, Itsuko Ishii
Organic Anion Transporting Polypeptide 2B1 Expression Correlates With Uptake of estrone-3-sulfate and Cell Proliferation in Estrogen Receptor-Positive Breast Cancer Cells
Drug Metab Pharmacokinet
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30(2):133-41
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Subramanian N, Kanwar JR, Kanwar RK, Sreemanthula J, Biswas J, Khetan V, Krishnakumar S.
EpCAM Aptamer-siRNA Chimera Targets and Regress Epithelial Cancer
PLoS One
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Felix Acheampong, Christopher Larbie, Regina Appiah-Opong,Fareed K.N.Arthur1andIsaac Tuffour
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European Journal of Medicinal Plants
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Wong CP, Seki A, Horiguchi K, Shoji T, Arai T, Nugroho AE, Hirasawa Y, Sato F, Kaneda T, Morita H.
Bisleuconothine A Induces Autophagosome Formation by Interfering with AKT-mTOR Signaling Pathway
J Nat Prod
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Selma Etteieb, Atsushi Kawachi, Junkyu Han, Jamila Tarhouni, Hiroko Isoda
Estrogenic Activity Assessment in Environmental Matrices by Means of In Vitro Cell-Based Bioassays Coupled With Molecular Investigation
CLEAN - Soil, Air, Water
2015
43:1279-1288
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Kan S, Koido S, Okamoto M, Hayashi K, Ito M, Kamata Y, Komita H, Ishidao T, Nagasaki E, Homma S.
Gemcitabine treatment enhances HER2 expression in low HER2-expressing breast cancer cells and enhances the antitumor effects of trastuzumab emtansine
Oncol Rep
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34(1):504-10
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Mira A, Shimizu K.
In vitro Cytotoxic Activities and Molecular Mechanisms of Angelica shikokiana Extract and its Isolated Compounds
Pharmacogn Mag
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11(Suppl 4):S564-9
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Karmakar UK, Ishikawa N, Toume K, Arai MA, Sadhu SK, Ahmed F, Ishibashi M.
Sesquiterpenes with TRAIL-resistance overcoming activity from Xanthium strumarium
Bioorg Med Chem
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23(15):4746-4754
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Yoshitaka Koseki, Yoshikazu Ikuta, Tatsuya Murakami, Tsunenobu Onodera, Hidetoshi Oikawa, Liman Cong, Hiroshi Tada, Kohsuke Gonda, Noriaki Ohuchi, Hitoshi Kasai
Cytotoxicity of Pure Nanodrugs of SN-38 and Podophyllotoxin Dimers in Human Cancer HepG2, KPL-4, and MCF-7 Cells
Molecular Crystals and Liquid Crystals
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622:1-5
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Kasai A, Arafuka S, Koshiba N, Takahashi D, Toshima K.
Systematic synthesis of low-molecular weight fucoidan derivatives and their effect on cancer cells
Org Biomol Chem
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13(42):10556-68
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MASANARI UMEMURA, Mayumi Katsumata, Itaru Sato, Akane Nagasako, Haruki Aoyama, Ayako Makino, Makoto Ohtake, Kayoko Oda, Kosuke Matsuo, Haruki Eguchi and Yoshihiro Ishikawa
Abstract 4398: Methotrexate derivative with intrinsic magnetism
AACR 106th Annual Meeting
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April 18-22
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15425
Sreejith Raveendran, Neha Chauhan, Vivekanandan Palaninathan, Yutaka Nagaoka, Yasuhiko Yoshida, Toru Maekawa, D. Sakthi Kumar
Extremophilic Polysaccharide for Biosynthesis and Passivation of Gold Nanoparticles and Photothermal Ablation of Cancer Cells
Particle & Particle Systems Characterization
2015
32:54-64
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Xu B, Ju Y, Cui Y, Song G, Iwase Y, Hosoi A, Morita Y.
tLyP-1-conjugated Au-nanorod@SiO(2) core-shell nanoparticles for tumor-targeted drug delivery and photothermal therapy.
Langmuir
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M. Sheikh Mohamed, Srivani Veeranarayanan, Hiroaki Minegishi, Yasushi Sakamoto, Yasuhiro Shimane, Yutaka Nagaoka, Atsushi Aki, Aby Cheruvathoor Poulose, Akinobu Echigo, Yasuhiko Yoshida, Toru Maekawa, D. Sakthi Kumar
Cytological and Subcellular Response of Cells Exposed to the Type-1 RIP Curcin and its Hemocompatibility Analysis
Scientific Reports
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Hamada T, Souda M, Yoshimura T, Sasaguri S, Hatanaka K, Tasaki T, Yoshioka T, Ohi Y, Yamada S, Tsutsui M, Umekita Y, Tanimoto A.
Anti-apoptotic effects of PCP4/PEP19 in human breast cancer cell lines: a novel oncotarget
Oncotarget
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5(15):6076-86
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AS1411 aptamer and folic acid functionalized pH-responsive ATRP fabricated pPEGMA-PCL-pPEGMA polymeric nanoparticles for targeted drug delivery in cancer therapy
Biomacromolecules
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Kariya A, Tabuchi Y, Yunoki T, Kondo T.
Identification of common gene networks responsive to mild hyperthermia in human cancer cells.
Int J Mol Med
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Takao M, Nagai Y, Torii T.
Cysteine-poor region-specific EpCAM monoclonal antibody recognizing native tumor cells with high sensitivity.
Monoclon Antib Immunodiagn Immunother
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Journal of Physics D: Applied Physics
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Maizatul Akmal Yahayu, Mawardi Rahmani, Najihah Mohd Hashim, Gwendoline Cheng Lian Ee, Mohd Aspollah Sukari, Abdah Md Akim
CYTOTOXIC AND ANTIMICROBIAL XANTHONES FROM Cratoxylum arborescens (Guttiferae)
Malaysian Journal of Science
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Ito Y, Mitani T, Harada N, Isayama A, Tanimori S, Takenaka S, Nakano Y, Inui H, Yamaji R.
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J Nutr Sci Vitaminol (Tokyo)
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Matsumoto J, Ariyoshi N, Ishii I, Kitada M.
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J Hum Genet
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Takahashi K, Orba Y, Kimura T, Wang L, Kohsaka S, Tsuda M, Tanino M, Nishihara H, Nagashima K, Sawa H, Tanaka S.
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Jpn J Infect Dis
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Athulya Aravind, Remya Nair, Sreejith Raveendran, Srivani Veeranarayanan, Yutaka Nagaoka, Takahiro Fukuda, Takahashi Hasumura, Hisao Morimoto, Yasuhiko Yoshida, Toru Maekawa, D. Sakthi Kumar
Aptamer conjugated paclitaxel and magnetic fluid loaded fluorescently tagged PLGA nanoparticles for targeted cancer therapy
Journal of Magnetism and Magnetic Materials
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Tripathi DN, Chowdhury R, Trudel LJ, Tee AR, Slack RS, Walker CL, Wogan GN.
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Proc Natl Acad Sci U S A
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Anal Chem
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Baiyao Xu, Yang Ju, Guanbin Song, Yanbin Cui
tLyP-1-conjugated mesoporous silica nanoparticles for tumor targeting and penetrating hydrophobic drug delivery
Journal of Nanoparticle Research
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TGFβ-activated Kinase 1 (TAK1)-binding Proteins (TAB) 2 and 3 Negatively Regulate Autophagy
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