| User's Publication |
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22646
Goldmacher VS, Gershteyn I, Chari R, Kovtun Y.
A bispecific anti-MUC16/anti-death receptor 5 antibody achieves effective and tumor-selective death receptor 5-mediated tumor regression.
Sci Rep
2025
15(1):9909
PubMed ID: 40121208
DOI: 10.1038/s41598-025-93927-0
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21833
Hata M, Kadoya Y, Ueno J, Taki M, Kodera M.
Dicopper Complexes of p-Cresol-2,6-bis(amide-tether-dpa4-X) (X = MeO and Cl): Selective ROS Generation and Cytotoxicity Enhancement Controlled by Electronic and Hydrophobic Effects of the MeO and Cl Groups.
Inorg Chem
2024
PubMed ID: 39011904
DOI: 10.1021/acs.inorgchem.4c01072
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18286
Amada K, Hijiya N, Ikarimoto S, Yanagihara K, Hanada T, Hidano S, Kurogi S, Tsukamoto Y, Nakada C, Kinoshita K, Hirashita Y, Uchida T, Shin T, Yada K, Hirashita T, Kobayashi T, Murakami K, Inomata M, Shirao K, Aoki M, Takekawa M, Moriyama M.
Involvement of clusterin expression in the refractory response of pancreatic cancer cells to a MEK inhibitor
Cancer Sci
2023
114(5):2189-2202
PubMed ID: 36694355
DOI: 10.1111/cas.15735
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19616
Masuo H, Kubota K, Shimizu A, Notake T, Miyazaki S, Yoshizawa T, Sakai H, Hayashi H, Soejima Y.
Increased mitochondria are responsible for the acquisition of gemcitabine resistance in pancreatic cancer cell lines
Cancer Sci
2023
114(11):4388-4400
PubMed ID: 37700464
DOI: 10.1111/cas.15962
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19722
Masuda T, Fukuda A, Yamakawa G, Omatsu M, Namikawa M, Sono M, Fukunaga Y, Nagao M, Araki O, Yoshikawa T, Ogawa S, Masuo K, Goto N, Hiramatsu Y, Muta Y, Tsuda M, Maruno T, Nakanishi Y, Masui T, Hatano E, Matsuzaki T, Noda M, Seno H.
Pancreatic RECK inactivation promotes cancer formation, epithelial-mesenchymal transition, and metastasis
J Clin Invest
2023
133(18):e161847
PubMed ID: 37712427
DOI: 10.1172/JCI161847
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20976
Liu Z, Hayashi H, Matsumura K, Ogata Y, Sato H, Shiraishi Y, Uemura N, Miyata T, Higashi T, Nakagawa S, Mima K, Imai K, Baba H.
Hyperglycaemia induces metabolic reprogramming into a glycolytic phenotype and promotes epithelial-mesenchymal transitions via YAP/TAZ-Hedgehog signalling axis in pancreatic cancer.
Br J Cancer
2023
28(5):844-856
PubMed ID: 36536047
DOI: 10.1038/s41416-022-02106-9
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21379
Hata M, Ueno J, Hitomi Y, Kodera M.
Roles of DNA Target in Cancer Cell-Selective Cytotoxicity by Dicopper Complexes with DNA Target/Ligand Conjugates.
ACS Omega
2023
8(31):28690-28701
PubMed ID: 37576680
DOI: 10.1021/acsomega.3c03387
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22123
Hu Y, Gao P, Xu G, Sun J, Xin W, Kong S, Ding H, Zhu J, Fang L.
Correlation of gene expression profiles to identify pancreatic cancer cell lines that best model primary human tumors
Transl Cancer Res
2023
12(4):980-991
PubMed ID: 37180676
DOI: 10.21037/tcr-23-173
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20773
Han JH, Kim YK, Kim H, Lee J, Oh MJ, Kim SB, Kim M, Kim KH, Yoon HJ, Lee MS, Minna JD, White MA, Kim HS.
Snail acetylation by autophagy-derived acetyl-coenzyme A promotes invasion and metastasis of KRAS-LKB1 co-mutated lung cancer cells.
Cancer Commun (Lond)
2022
PubMed ID: 35838183
DOI: 10.1002/cac2.12332
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20246
Giuliani V, Miller MA, Liu CY, Hartono SR, Class CA, Bristow CA, Suzuki E, Sanz LA, Gao G, Gay JP, Feng N, Rose JL, Tomihara H, Daniele JR, Peoples MD, Bardenhagen JP, Geck Do MK, Chang QE, Vangamudi B, Vellano C, Ying H, Deem AK, Do KA, Genovese G, Marszalek JR, Kovacs JJ, Kim M, Fleming JB, Guccione E, Viale A, Maitra A, Emilia Di Francesco M, Yap TA, Jones P, Draetta G, Carugo A, Chedin F, Heffernan TP.
PRMT1-dependent regulation of RNA metabolism and DNA damage response sustains pancreatic ductal adenocarcinoma.
Nat Commun
2021
12(1):4626
PubMed ID: 34330913
DOI: 10.1038/s41467-021-24798-y
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20431
Shiozaki A, Konishi T, Kosuga T, Kudou M, Kurashima K, Inoue H, Shoda K, Arita T, Konishi H, Morimura R, Komatsu S, Ikoma H, Toma A, Kubota T, Fujiwara H, Okamoto K, Otsuji E.
Roles of voltage‑gated potassium channels in the maintenance of pancreatic cancer stem cells.
Int J Oncol
2021
59(4)
PubMed ID: 34414448
DOI: 10.3892/ijo.2021.5256
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16115
Masuo K, Chen R, Yogo A, Sugiyama A, Fukuda A, Masui T, Uemoto S, Seno H, Takaishi S.
SNAIL2 contributes to tumorigenicity and chemotherapy resistance in pancreatic cancer by regulating IGFBP2
Cancer Sci
2021
112(12):4987-4999
PubMed ID: 34628696
DOI: 10.1111/cas.15162
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22303
Itoyama R, Yasuda-Yoshihara N, Kitamura F, Yasuda T, Bu L, Yonemura A, Uchihara T, Arima K, Hu X, Jun Z, Okamoto Y, Akiyama T, Yamashita K, Nakao Y, Yusa T, Kitano Y, Higashi T, Miyata T, Imai K, Hayashi H, Yamashita YI, Mikawa T, Kondoh H, Baba H, Ishimoto T.
Metabolic shift to serine biosynthesis through 3-PG accumulation and PHGDH induction promotes tumor growth in pancreatic cancer
Cancer Lett
2021
523:29-42
PubMed ID: 34508795
DOI: 10.1016/j.canlet.2021.09.007
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13240
Onodera T, Momose I, Adachi H, Yamazaki Y, Sawa R, Ohba SI, Kawada M.
Human pancreatic cancer cells under nutrient deprivation are vulnerable to redox system inhibition.
J Biol Chem
2020
PubMed ID: 32978257
DOI: 10.1074/jbc.RA120.013893
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14280
Hobbs GA, Baker NM, Miermont AM, Thurman RD, Pierobon M, Tran TH, Anderson AO, Waters AM, Diehl JN, Papke B, Hodge RG, Klomp JE, Goodwin CM, DeLiberty JM, Wang J, Ng RWS, Gautam P, Bryant KL, Esposito D, Campbell SL, Petricoin EF 3rd, Simanshu DK, Aguirre AJ, Wolpin BM, Wennerberg K, Rudloff U, Cox AD, Der CJ.
Atypical KRAS G12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer
Cancer Discov
2020
10(1):104-123
PubMed ID: 31649109
DOI: 10.1158/2159-8290.CD-19-1006
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5027
Nishizawa N1, Harada H1, Kumamoto Y1, Kaizu T, Katoh H, Tajima H, Ushiku H, Yokoi K, Igarashi K, Fujiyama Y, Okuwaki K, Iwai T, Watanabe M, Yamashita K1
Diagnostic potential of hypermethylation of the cysteine dioxygenase 1 gene (CDO1) promoter DNA in pancreatic cancer.
Cancer Sci
2019
110(9):2846-2855
PubMed ID: 31325200
DOI: 10.1111/cas.14134
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5030
Tsukamoto M, Imai K, Ishimoto T, Komohara Y, Yamashita YI, Nakagawa S, Umezaki N, Yamao T, Kitano Y, Miyata T, Arima K, Okabe H, Baba Y, Chikamoto A, Ishiko T, Hirota M, Baba H.
PD-L1 expression enhancement by infiltrating macrophage-derived tumor necrosis factor-α leads to poor pancreatic cancer prognosis.
Cancer Sci
2019
110(1):310-320
PubMed ID: 30426611
DOI: 10.1111/cas.13874
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11631
Konishi T, Shiozaki A, Kosuga T, Kudou M, Shoda K, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, Marunaka Y, Otsuji E.
LRRC8A Expression Influences Growth of Esophageal Squamous Cell Carcinoma.
Am. J. Pathol.
2019
PubMed ID: 31323188
DOI: 10.1016/j.ajpath.2019.06.006
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11811
Mohammad GH, Vassileva V, Acedo P, Olde Damink SWM, Malago M, Dhar DK, Pereira SP.
Targeting Pyruvate Kinase M2 and Lactate Dehydrogenase A Is an Effective Combination Strategy for the Treatment of Pancreatic Cancer.
Cancers (Basel)
2019
11(9):1372
PubMed ID: 31527446
DOI: 10.3390/cancers11091372
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11243
Vilimas T, Wang AQ, Patnaik S, Hughes EA, Singleton MD, Knotts Z, Li D, Frankowski K, Schlomer JJ, Guerin TM, Springer S, Drennan C, Dextras C, Wang C, Gilbert D, Southall N, Ferrer M, Huang S, Kozlov S, Marugan J, Xu X, Rudloff U.
Pharmacokinetic evaluation of the PNC disassembler metarrestin in wild-type and Pdx1-Cre;LSL-KrasG12D/+;Tp53R172H/+ (KPC) mice, a genetically engineered model of pancreatic cancer.
Cancer Chemother. Pharmacol.
2018
PubMed ID: 30306263
DOI: 10.1007/s00280-018-3699-0
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10320
Kasai S, Sasaki T, Watanabe A, Nishiya M, Yasuhira S, Shibazaki M, Maesawa C.
Bcl-2/Bcl-xL inhibitor ABT-737 sensitizes pancreatic ductal adenocarcinoma to paclitaxel-induced cell death.
Oncol Lett
2017
14:903-908
PubMed ID: 28693250
DOI: 10.3892/ol.2017.6211
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9592
Hijiya N, Tsukamoto Y, Nakada C, Tung Nguyen L, Kai T, Matsuura K, Shibata K, Inomata M, Uchida T, Tokunaga A, Amada K, Shirao K, Yamada Y, Mori H, Takeuchi I, Seto M, Aoki M, Takekawa M, Moriyama M.
Genomic Loss of DUSP4 Contributes to the Progression of Intraepithelial Neoplasm of Pancreas to Invasive Carcinoma.
Cancer Res.
2016
76:2612-25
PubMed ID: 26941286
DOI: 10.1158/0008-5472.CAN-15-1846
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12659
Mohammad GH, Olde Damink SW, Malago M, Dhar DK, Pereira SP.
Pyruvate Kinase M2 and Lactate Dehydrogenase A Are Overexpressed in Pancreatic Cancer and Correlate with Poor Outcome
PLoS One
2016
11(3):e0151635
PubMed ID: 26989901
DOI: 10.1371/journal.pone.0151635
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7168
Miyamae M, Komatsu S, Ichikawa D, Kawaguchi T, Hirajima S, Okajima W, Ohashi T, Imamura T, Konishi H, Shiozaki A, Morimura R, Ikoma H, Ochiai T, Okamoto K, Taniguchi H, Otsuji E.
Plasma microRNA profiles: identification of miR-744 as a novel diagnostic and prognostic biomarker in pancreatic cancer.
Br. J. Cancer
2015
113:1467-76
PubMed ID: 26505678
DOI: 10.1038/bjc.2015.366
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7348
Kobashigawa S, Morikawa K, Mori H, Kashino G.
Gemcitabine Induces Radiosensitization Through Inhibition of RAD51-dependent Repair for DNA Double-strand Breaks.
Anticancer Res.
2015
35:2731-7
PubMed ID: 25964552
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7408
Terao N, Takamatsu S, Minehira T, Sobajima T, Nakayama K, Kamada Y, Miyoshi E.
Fucosylation is a common glycosylation type in pancreatic cancer stem cell-like phenotypes.
World J. Gastroenterol.
2015
21:3876-87
PubMed ID: 25852272
DOI: 10.3748/wjg.v21.i13.3876
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5019
Tomizawa M, Shinozaki F, Motoyoshi Y, Sugiyama T, Yamamoto S, Ishige N.
SU11274 suppresses proliferation and motility of pancreatic cancer cells.
Oncol Lett
2015
10(3):1468-1472
PubMed ID: 26622692
DOI: 10.3892/ol.2015.3452
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5025
Sakamoto K, Imai K, Higashi T, Taki K, Nakagawa S, Okabe H, Nitta H, Hayashi H, Chikamoto A, Ishiko T, Beppu T, Baba H.
Significance of P-cadherin overexpression and possible mechanism of its regulation in intrahepatic cholangiocarcinoma and pancreatic cancer.
Cancer Sci
2015
106(9):1153-62
PubMed ID: 26132727
DOI: 10.1111/cas.12732
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5018
Tomizawa M, Shinozaki F, Sugiyama T, Yamamoto S, Sueishi M, Yoshida T.
Frizzled-2: A potential novel target for molecular pancreatic cancer therapy.
Oncol Lett
2014
7(1):74-78
PubMed ID: 24348824
DOI: 10.3892/ol.2013.1681
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5024
Kawaguchi T, Komatsu S, Ichikawa D, Morimura R, Tsujiura M, Konishi H, Takeshita H, Nagata H, Arita T, Hirajima S, Shiozaki A, Ikoma H, Okamoto K, Ochiai T, Taniguchi H, Otsuji E.
Clinical impact of circulating miR-221 in plasma of patients with pancreatic cancer.
Br J Cancer
2013
108(2):361-9
PubMed ID: 23329235
DOI: 10.1038/bjc.2012.546
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3714
Kato N, Yamamoto H, Adachi Y, Ohashi H, Taniguchi H, Suzuki H, Nakazawa M, Kaneto H, Sasaki S, Imai K, Shinomura Y.
Cancer detection by ubiquitin carboxyl-terminal esterase L1 methylation in pancreatobiliary fluids.
World J Gastroenterol
2013
19(11):1718-27
PubMed ID: 23555160
DOI: 10.3748/wjg.v19.i11.1718
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5020
Tomizawa M, Shinozaki F, Sugiyama T, Yamamoto S, Sueishi M, Yoshida T.
nsulin-like growth factor I receptor involvement in proliferation of NOR-P1 cells in serum-free media.
J Cell Biochem
2012
113(8):2714-20
PubMed ID: 22441995
DOI: 10.1002/jcb.24149
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5026
Waraya M, Yamashita K, Katoh H, Ooki A, Kawamata H, Nishimiya H, Nakamura K, Ema A, Watanabe M.
Cancer specific promoter CpG Islands hypermethylation of HOP homeobox (HOPX) gene and its potential tumor suppressive role in pancreatic carcinogenesis.
BMC Cancer
2012
12:397
PubMed ID: 22958219
DOI: 10.1186/1471-2407-12-397
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5032
Igarashi S, Matsubara T, Harada K, Ikeda H, Sato Y, Sasaki M, Matsui O, Nakanuma Y.
Bile duct expression of pancreatic and duodenal homeobox 1 in perihilar cholangiocarcinogenesis.
Histopathology
2012
61(2):266-76
PubMed ID: 22594685
DOI: 10.1111/j.1365-2559.2012.04218.x
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12868
Yoshida M, Takimoto R, Murase K, Sato Y, Hirakawa M, Tamura F, Sato T, Iyama S, Osuga T, Miyanishi K, Takada K, Hayashi T, Kobune M, Kato J.
Targeting anticancer drug delivery to pancreatic cancer cells using a fucose-bound nanoparticle approach
PLoS One
2012
7(7):e39545
PubMed ID: 22808043
DOI: 10.1371/journal.pone.0039545
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7643
Morimura R, Komatsu S, Ichikawa D, Takeshita H, Tsujiura M, Nagata H, Konishi H, Shiozaki A, Ikoma H, Okamoto K, Ochiai T, Taniguchi H, Otsuji E.
Novel diagnostic value of circulating miR-18a in plasma of patients with pancreatic cancer.
Br. J. Cancer
2011
105:1733-40
PubMed ID: 22045190
DOI: 10.1038/bjc.2011.453
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8294
Tomizawa M, Shinozaki F, Sugiyama T, Yamamoto S, Sueishi M, Yoshida T.
Insulin-like growth factor-I receptor in proliferation and motility of pancreatic cancer.
World J. Gastroenterol.
2010
16:1854-8
PubMed ID: 20397262
DOI: 10.3748/wjg.v16.i15.1854
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5022
Mitsuno M, Kitajima Y, Ohtaka K, Kai K, Hashiguchi K, Nakamura J, Hiraki M, Noshiro H, Miyazaki K.
Tranilast strongly sensitizes pancreatic cancer cells to gemcitabine via decreasing protein expression of ribonucleotide reductase 1.
Int J Oncol
2010
36(2):341-9
PubMed ID: 20043067
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8610
Suzuki J, Murakami Y, Samejima K, Ohtani KK, Oka T.
Antizyme is necessary for conversion of pancreatic tumor cells into glucagon-producing differentiated cells.
Endocr. Relat. Cancer
2009
16:649-59
PubMed ID: 19349429
DOI: 10.1677/ERC-09-0004
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6410
Danjoh I, Sone H, Noda N, Iimura E, Nagayoshi M, Saijo K, Hiroyama T, Nakamura Y.
Is parainfluenza virus a threatening virus for human cancer cell lines?
Hum Cell
2009
22(3):81-4
PubMed ID: 19624309
DOI: 10.1111/j.1749-0774.2009.00071.x
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5016
Inami K1, Kajino K, Abe M, Hagiwara Y, Maeda M, Suyama M, Watanabe S, Hino O.
Secretion of N-ERC/mesothelin and expression of C-ERC/mesothelin in human pancreatic ductal carcinoma.
Oncol Rep
2008
20(6):1375-80
PubMed ID: 19020717
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