| 利用者成果(英) |
|
19878
Sun H, Kawano M, Iwasaki T, Itonaga I, Kubota Y, Tsumura H, Tanaka K.
MicroRNA-329-3p inhibits the Wnt/β-catenin pathway and proliferation of osteosarcoma cells by targeting transcription factor 7-like 1
Oncol Res
2024
32(3):463-476
PubMed ID: 38370338
DOI: 10.32604/or.2023.044085
|
|
21672
Funato N, Heliövaara A, Boeckx C.
A regulatory variant impacting TBX1 expression contributes to basicranial morphology in Homo sapiens.
Am J Hum Genet
2024
111(5):939-953
PubMed ID: 38608674
DOI: 10.1016/j.ajhg.2024.03.012
|
|
22009
Ishizawa M, Takano M, Kittaka A, Matsumoto T, Makishima M.
2α-Substituted Vitamin D Derivatives Effectively Enhance the Osteoblast Differentiation of Dedifferentiated Fat Cells.
Biomolecules
2024
14(6)
PubMed ID: 38927109
DOI: 10.3390/biom14060706
|
|
19876
Maekawa K, Ishizawa M, Ikawa T, Sajiki H, Matsumoto T, Tokiwa H, Makishima M, Yamada S.
Syntheses of 25-Adamantyl-25-alkyl-2-methylidene-1α,25-dihydroxyvitamin D3 Derivatives with Structure-Function Studies of Antagonistic and Agonistic Active Vitamin D Analogs
Biomolecules
2023
13(7):1082
PubMed ID: 37509118
DOI: 10.3390/biom13071082
|
|
21135
Nakajima M, Koido M, Guo L, Terao C, Ikegawa S.
A novel CCDC91 isoform associated with ossification of the posterior longitudinal ligament of the spine works as a non-coding RNA to regulate osteogenic genes.
Am J Hum Genet
2023
110(4):638-647
PubMed ID: 36990086
DOI: 10.1016/j.ajhg.2023.03.004
|
|
21339
Kawano M, Tanaka K, Itonaga I, Iwasaki T, Kubota Y, Tsumura H.
The anti-oncogenic effect of 17-DMAG via the inactivation of HSP90 and MET pathway in osteosarcoma cells.
Oncol Res
2023
31(5):631-643
PubMed ID: 37547755
DOI: 10.32604/or.2023.029745
|
|
17550
Yamawaki Y, So H, Oue K, Asano S, Furusho H, Miyauchi M, Tanimoto K, Kanematsu T.
Imipramine prevents Porphyromonas gingivalis lipopolysaccharide-induced microglial neurotoxicity
Biochem Biophys Res Commun
2022
634:92-99
PubMed ID: 36240654
DOI: 10.1016/j.bbrc.2022.09.109
|
|
17824
Asanuma K, Nakamura T, Nakamura K, Hagi T, Okamoto T, Kita K, Matsuyama Y, Yoshida K, Asanuma Y, Sudo A.
Compound Library Screening for Synergistic Drug Combinations: mTOR Inhibitor and Proteasome Inhibitor Effective Against Osteosarcoma Cells
Anticancer Res
2022
42(9):4319-4328
PubMed ID: 36039444
DOI: 10.21873/anticanres.15932
|
|
20494
Hassani A, Khoshfetrat AB, Rahbarghazi R, Sakai S.
Collagen and nano-hydroxyapatite interactions in alginate-based microcapsule provide an appropriate osteogenic microenvironment for modular bone tissue formation.
Carbohydr Polym
2022
277:118807
PubMed ID: 34893227
DOI: 10.1016/j.carbpol.2021.118807
|
|
20424
Yasunaga M, Kobayashi F, Sogo Y, Murotomi K, Hirose M, Hara Y, Yamazaki M, Ito A.
The enhancing effects of heparin on the biological activity of FGF-2 in heparin-FGF-2-calcium phosphate composite layers.
Acta Biomater
2022
PubMed ID: 35697197
DOI: 10.1016/j.actbio.2022.06.013
|
|
20765
Ishikawa A, Waseda M, Ishii T, Kaneko MK, Kato Y, Kaneko S.
Improved anti-solid tumor response by humanized anti-podoplanin chimeric antigen receptor transduced human cytotoxic T cells in an animal model.
Genes Cells
2022
PubMed ID: 35790497
DOI: 10.1111/gtc.12972
|
|
20833
Tanaka K, Suzuki K, Miyashita K, Wakasa K, Kawano M, Nakatsu Y, Tsumura H, Yoshida MA, Oda S.
Activation of recombinational repair in Ewing sarcoma cells carrying EWS-FLI1 fusion gene by chromosome translocation.
Sci Rep
2022
12(1):14764
PubMed ID: 36042341
DOI: 10.1038/s41598-022-19164-x
|
|
19294
Kawatani M, Aono H, Shimizu T, Ohkura S, Hiranuma S, Muroi M, Ogawa N, Ohishi T, Ohba SI, Kawada M, Yamazaki K, Dan S, Osada H.
Identification of Dihydroorotate Dehydrogenase Inhibitors─Indoluidins─That Inhibit Cancer Cell Growth
ACS Chem Biol
2021
16(11):2570-2580
PubMed ID: 34730931
DOI: 10.1021/acschembio.1c00625
|
|
13419
Suzuki S, Yuan H, Hirata-Tsuchiya S, Yoshida K, Sato A, Nemoto E, Shiba H, Yamada S.
DMP-1 promoter-associated antisense strand non-coding RNA, panRNA-DMP-1, physically associates with EGFR to repress EGF-induced squamous cell carcinoma migration.
Mol Cell Biochem
2021
PubMed ID: 33420898
DOI: 10.1007/s11010-020-04046-5
|
|
20332
Kawano M, Iwasaki T, Itonaga I, Kubota Y, Tanaka K, Tsumura H.
Analysis of the signal cross talk via CCL26 in the tumor microenvironment in osteosarcoma.
Sci Rep
2021
11(1):18099
PubMed ID: 34518591
DOI: 10.1038/s41598-021-97153-2
|
|
15514
Ohya S, Kajikuri J, Endo K, Kito H, Elboray EE, Suzuki T.
Ca 2+ -activated K + channel K Ca 1.1 as a therapeutic target to overcome chemoresistance in three-dimensional sarcoma spheroid models
Cancer Sci
2021
112(9):3769-3783
PubMed ID: 34181803
DOI: 10.1111/cas.15046
|
|
16865
Ando T, Suzuki-Karasaki M, Suzuki-Karasaki M, Ichikawa J, Ochiai T, Yoshida Y, Haro H, Suzuki-Karasaki Y.
Combined Anticancer Effect of Plasma-Activated Infusion and Salinomycin by Targeting Autophagy and Mitochondrial Morphology
Front Oncol
2021
11:593127
PubMed ID: 34150606
DOI: 10.3389/fonc.2021.593127
|
|
13057
Ichikawa J, Ando T, Kawasaki T, Sasaki T, Shirai T, Tsukiji N, Kimura Y, Aoki K, Hayakawa K, Suzuki-Inoue K, Saitoh M, Haro H.
Role of Platelet C-Type Lectin-Like Receptor 2 in Promoting Lung Metastasis in Osteosarcoma.
J Bone Miner Res
2020
PubMed ID: 32479683
DOI: 10.1002/jbmr.4045
|
|
13253
Fujiwara S, Kawamoto T, Kawakami Y, Koterazawa Y, Hara H, Takemori T, Kitayama K, Yahiro S, Kakutani K, Matsumoto T, Matsushita T, Niikura T, Koyanagi-Aoi M, Aoi T, Kuroda R, Akisue T.
Acquisition of cancer stem cell properties in osteosarcoma cells by defined factors.
Stem Cell Res Ther
2020
PubMed ID: 33008481
DOI: 10.1186/s13287-020-01944-9
|
|
13306
Ando T, Ichikawa J, Fujimaki T, Taniguchi N, Takayama Y, Haro H.
Gemcitabine and Rapamycin Exhibit Additive Effect against Osteosarcoma by Targeting Autophagy and Apoptosis.
Cancers (Basel)
2020
PubMed ID: 33114161
DOI: 10.3390/cancers12113097
|
|
13849
Hirata Y, Nada Y, Yamada Y, Toyama T, Fukunaga K, Hwang GW, Noguchi T, Matsuzawa A.
Elaidic Acid Potentiates Extracellular ATP-Induced Apoptosis via the P2X 7-ROS-ASK1-p38 Axis in Microglial Cell Lines
Biol Pharm Bull
2020
43(10):1562-1569
PubMed ID: 32999166
DOI: 10.1248/bpb.b20-00409
|
|
14495
Kohno K, Yamada W, Ishitsuka A, Sekine M, Virgona N, Ota M, Yano T.
Tocotrienol-rich fraction from annatto ameliorates expression of lysyl oxidase in human osteoblastic MG-63 cells
Biosci Biotechnol Biochem
2020
84(3):526-535
PubMed ID: 31743080
DOI: 10.1080/09168451.2019.1693252
|
|
11414
Ishibashi Y, Nakamura O, Yamagami Y, Nishimura H, Fukuoka N, Yamamoto T.
Chloroquine Enhances Rapamycin-induced Apoptosis in MG63 Cells.
Anticancer Res.
2019
PubMed ID: 30711941
DOI: 10.21873/anticanres.13159
|
|
11668
Aiko Ono-Ohmachi, Hiroshi M. Ueno, Yoshikazu Morita, Ken Kato
Collagen production ability of milk basic protein is dependent on stimulatory effect of transforming growth factor-β1 and β2
International Dairy Journal
2019
DOI: 10.1016/j.idairyj.2019.05.019
|
|
11978
Asano N, Takeshima H, Yamashita S, Takamatsu H, Hattori N, Kubo T, Yoshida A, Kobayashi E, Nakayama R, Matsumoto M, Nakamura M, Ichikawa H, Kawai A, Kondo T, Ushijima T.
Epigenetic reprogramming underlies efficacy of DNA demethylation therapy in osteosarcomas.
Sci Rep
2019
PubMed ID: 31889115
DOI: 10.1038/s41598-019-56883-0
|
|
12453
Kubo S, Takagi-Kimura M, Kasahara N.
Efficient tumor transduction and antitumor efficacy in experimental human osteosarcoma using retroviral replicating vectors
Cancer Gene Ther
2019
;26(1-2):41-47
PubMed ID: 30042500
DOI: 10.1038/s41417-018-0037-y
|
|
10809
Kawano M, Tanaka K, Itonaga I, Iwasaki T, Tsumura H.
Interaction between human osteosarcoma and mesenchymal stem cells via an interleukin-8 signaling loop in the tumor microenvironment.
Cell Commun. Signal
2018
16:13
PubMed ID: 29625612
DOI: 10.1186/s12964-018-0225-2
|
|
4424
Eisuke DOMAE, Kaname TSUJI, Yuya HIRAI, Yoshihiro YOSHIKAWA, Aiko KAMADA, Shosuke MORITA, Seiji GODA, Takashi IKEO
Synergistic effect of IL2, IL12 and IL18 on the activation of ex vivoexpanded human Vγ9Vδ2 T cells
J Osaka Dent Univ
2018
52 : 51−57
DOI: 10.18905/jodu.52.1_51
|
|
4291
Yu J, Xia H, Teramoto A, Ni QQ.
The effect of hydroxyapatite nanoparticles on mechanical behavior and biological performance of porous shape memory polyurethane scaffolds.
J Biomed Mater Res A
2018
PubMed ID: 28880433
DOI: 10.1002/jbm.a.36214
|
|
4292
Saito M, Ichikawa J, Ando T, Schoenecker JG, Ohba T, Koyama K, Suzuki-Inoue K, Haro H.
Platelet-Derived TGF-β Induces Tissue Factor Expression via the Smad3 Pathway in Osteosarcoma Cells.
J. Bone Miner. Res.
2018
PubMed ID: 29949655
DOI: 10.1002/jbmr.3537
|
|
14701
Otero R, Ishizawa M, Numoto N, Ikura T, Ito N, Tokiwa H, Mouriño A, Makishima M, Yamada S.
25 S-Adamantyl-23-yne-26,27-dinor-1α,25-dihydroxyvitamin D 3: Synthesis, Tissue Selective Biological Activities, and X-ray Crystal Structural Analysis of Its Vitamin D Receptor Complex
J Med Chem
2018
61(15):6658-6673
PubMed ID: 29989817
DOI: 10.1021/acs.jmedchem.8b00427
|
|
9956
Morishita M, Kawamoto T, Hara H, Onishi Y, Ueha T, Minoda M, Katayama E, Takemori T, Fukase N, Kurosaka M, Kuroda R, Akisue T.
AICAR induces mitochondrial apoptosis in human osteosarcoma cells through an AMPK-dependent pathway.
Int. J. Oncol.
2017
50:23-30
PubMed ID: 27878239
DOI: 10.3892/ijo.2016.3775
|
|
10070
Fukada T, Sakajiri H, Kuroda M, Kioka N, Sugimoto K.
Fluid shear stress applied by orbital shaking induces MG-63 osteosarcoma cells to activate ERK in two phases through distinct signaling pathways.
Biochem Biophys Rep
2017
9:257-265
PubMed ID: 28956013
DOI: 10.1016/j.bbrep.2017.01.004
|
|
10571
Kamata E, Kawamoto T, Ueha T, Hara H, Fukase N, Minoda M, Morishita M, Takemori T, Fujiwara S, Nishida K, Kuroda R, Kurosaka M, Akisue T.
Synergistic Effects of a Smac Mimetic with Doxorubicin Against Human Osteosarcoma.
Anticancer Res.
2017
37:6097-6106
PubMed ID: 29061790
DOI: 10.21873/anticanres.12058
|
|
10906
The effect of macro/micro combination pore structure of biphasic calcium phosphate scaffold on bioactivity
Ceramics International
2017
43, 3540-3546
DOI: 10.1016/j.ceramint.2016.11.156
|
|
9459
Sachiko Hiromoto, Tomohiko Yamazaki
Micromorphological Effect of Calcium Phosphate Coating on Compatibility of Magnesium Alloy With Osteoblast
Sci Technol Adv Mater
2017
18(1):96-109
PubMed ID: 28179963
DOI: 10.1080/14686996.2016.1266238
|
|
14447
Takayuki Takei, Kohei Fukumoto, So Danjo, Takuma Yoshinaga, Hiroto Nishimata, Masahiro Yoshida
In Vitro and in Vivo Characterization of Hydroxyapatite/Chitosan-Gluconic Acid Conjugate Scaffolds
Journal of Chemical Engineering of Japan
2017
50:577-582
DOI: 10.1252/jcej.16we202
|
|
10919
Antitumor activities of BIBF 1120, BI 860585, and BI 836845 in preclinical models of sarcoma
Integr Mol Med
2016
3: 755-760
DOI: 10.15761/IMM.1000239
|
|
12960
Usui M, Okamatsu Y, Sato T, Hanatani T, Moritani Y, Sano K, Yamamoto M, Nakashima K.
Thymus-expressed chemokine enhances Porphyromonas gingivalis LPS-induced osteoclast formation via NFATc1 activation
Arch Oral Biol
2016
66:77-85
PubMed ID: 26921718
DOI: 10.1016/j.archoralbio.2016.02.011
|
|
14959
Iwasaki T, Tanaka K, Kawano M, Itonaga I, Tsumura H.
Tumor-suppressive microRNA-let-7a inhibits cell proliferation via targeting of E2F2 in osteosarcoma cells
Int J Oncol
2015
46(4):1543-50
PubMed ID: 25647078
DOI: 10.3892/ijo.2015.2867
|
|
15245
Krishnan V, Kasuya Y, Ji Q, Sathish M, Shrestha LK, Ishihara S, Minami K, Morita H, Yamazaki T, Hanagata N, Miyazawa K, Acharya S, Nakanishi W, Hill JP, Ariga K.
Vortex-aligned fullerene nanowhiskers as a scaffold for orienting cell growth
ACS Appl Mater Interfaces
2015
7(28):15667-73
PubMed ID: 26115554
DOI: 10.1021/acsami.5b04811
|
|
6862
Ito T, Sasaki M, Taguchi T.
Enhanced ALP activity of MG63 cells cultured on hydroxyapatite-poly(ethylene glycol) hydrogel composites prepared using EDTA-OH
Biomed Mater
2015
10(1):015025
PubMed ID: 25730608
DOI: 10.1088/1748-6041/10/1/015025
|
|
12955
Yusuke Watarai, Michiyasu Ishizawa, Teikichi Ikura, Flavia C. M. Zacconi, Shigeyuki Uno, Nobutoshi Ito, Antonio Mouriño, Hiroaki Tokiwa, Makoto Makishima, Sachiko Yamada
Synthesis, Biological Activities, and X-ray Crystal Structural Analysis of 25-Hydroxy-25(or 26)-adamantyl-17-[20(22),23-diynyl]-21-norvitamin D Compounds
Journal of Medicinal Chemistry
2015
58:9510-9521
PubMed ID: 26613420
DOI: 10.1021/acs.jmedchem.5b00792
|
|
4056
Xu B, Ju Y, Cui Y, Song G, Iwase Y, Hosoi A, Morita Y.
tLyP-1-conjugated Au-nanorod@SiO(2) core-shell nanoparticles for tumor-targeted drug delivery and photothermal therapy.
Langmuir
2014
30:7789-97
PubMed ID: 24921672
DOI: 10.1021/la500595b
|
|
5605
Iizuka S, Oridate N, Nashimoto M, Fukuda S, Tamura M.
Growth inhibition of head and neck squamous cell carcinoma cells by sgRNA targeting the cyclin D1 mRNA based on TRUE gene silencing.
PLoS One
2014
9(12):e114121
PubMed ID: 25437003
DOI: 10.1371/journal.pone.0114121
|
|
15802
Takagi-Kimura M, Yamano T, Tagawa M, Kubo S.
Oncolytic virotherapy for osteosarcoma using midkine promoter-regulated adenoviruses
Cancer Gene Ther
2014
21(3):126-32
PubMed ID: 24577130
DOI: 10.1038/cgt.2014.7
|
|
15902
Toshimasa UEMURA
Construction of Three Dimensional Tissues of Osteosarcoma MG63 Cells Using a Rotating Wall Vessel Bioreactor and the Dose-Dependent Effect of Doxorubicin
Nano Biomedicine
2014
6(1), 21-26
DOI: 10.11344/nano.6.21
|
|
7675
Ichikawa J, Cole HA, Magnussen RA, Mignemi NA, Butler M, Holt GE, O'Rear L, Yuasa M, Pabla B, Haro H, Cates JM, Hamm HE, Schwartz HS, Schoenecker JG.
Thrombin induces osteosarcoma growth, a function inhibited by low molecular weight heparin in vitro and in vivo: procoagulant nature of osteosarcoma.
Cancer
2012
118:2494-506
PubMed ID: 21953059
DOI: 10.1002/cncr.26518
|
|
18582
Hatoh T, Maeda T, Takeuchi K, Ogikubo O, Uchiyama S, Otsuka T, Ohkubo I, Ogita H.
Domain 5 of high molecular weight kininogen inhibits collagen-mediated cancer cell adhesion and invasion in association with α-actinin-4
Biochem Biophys Res Commun
2012
427(3):497-502
PubMed ID: 23000411
DOI: 10.1016/j.bbrc.2012.09.079
|
|
15738
Kawai S, Amano A.
BRCA1 regulates microRNA biogenesis via the DROSHA microprocessor complex
J Cell Biol
2012
197(2):201-8
PubMed ID: 22492723
DOI: 10.1083/jcb.201110008
|
|
15760
Sasaki M, Inoue M, Katada Y, Nishida Y, Taniguchi A, Hiromoto S, Taguchi T.
Preparation and biological evaluation of hydroxyapatite-coated nickel-free high-nitrogen stainless steel
Sci Technol Adv Mater
2012
13(6):064213
PubMed ID: 27877540
DOI: 10.1088/1468-6996/13/6/064213
|
|
15980
Kenichirou YASUI, Yoshiya HASHIMOTO, Shunsuke BABA, Shigeki HONTSU, Naoyuki MATSUMOTO
Evaluation of Bone Regeneration of Apatite Coating Poly-L-lactide Scaffold in Rat Calvarial Defects
Nano Biomedicine
2012
4:133-142
DOI: 10.11344/nano.4.133
|
|
18251
Rouleau C, Smale R, Fu YS, Hui G, Wang F, Hutto E, Fogle R, Jones CM, Krumbholz R, Roth S, Curiel M, Ren Y, Bagley RG, Wallar G, Miller G, Schmid S, Horten B, Teicher BA.
Endosialin is expressed in high grade and advanced sarcomas: evidence from clinical specimens and preclinical modeling
Int J Oncol
2011
39(1):73-89
PubMed ID: 21537839
DOI: 10.3892/ijo.2011.1020
|
|
7896
Goto K, Tatsumi K, Nagata T, Komizu Y, Ueoka R.
Specific interaction between Ca2+ and anionic lipids in cancer cells along with apoptosis.
Biol. Pharm. Bull.
2011
34:439-42
PubMed ID: 21372400
DOI: 10.1248/bpb.34.439
|
|
8031
Iizuka S, Kudo Y, Yoshida M, Tsunematsu T, Yoshiko Y, Uchida T, Ogawa I, Miyauchi M, Takata T.
Ameloblastin regulates osteogenic differentiation by inhibiting Src kinase via cross talk between integrin beta1 and CD63.
Mol. Cell. Biol.
2011
31:783-92
PubMed ID: 21149578
DOI: 10.1128/MCB.00912-10
|
|
8073
Niinaka Y, Harada K, Fujimuro M, Oda M, Haga A, Hosoki M, Uzawa N, Arai N, Yamaguchi S, Yamashiro M, Raz A.
Silencing of autocrine motility factor induces mesenchymal-to-epithelial transition and suppression of osteosarcoma pulmonary metastasis.
Cancer Res.
2010
70:9483-93
PubMed ID: 20978190
DOI: 10.1158/0008-5472.CAN-09-3880
|
|
8446
Hashiguchi K, Tsuchiya H, Tomita A, Ueda C, Akechi Y, Sakabe T, Kurimasa A, Nozaki M, Yamada T, Tsuchida S, Shiota G.
Involvement of ETS1 in thioredoxin-binding protein 2 transcription induced by a synthetic retinoid CD437 in human osteosarcoma cells.
Biochem. Biophys. Res. Commun.
2010
391:621-6
PubMed ID: 19932085
DOI: 10.1016/j.bbrc.2009.11.109
|
|
18573
Tsurushima H, Marushima A, Suzuki K, Oyane A, Sogo Y, Nakamura K, Matsumura A, Ito A.
Enhanced bone formation using hydroxyapatite ceramic coated with fibroblast growth factor-2
Acta Biomater
2010
6(7):2751-9
PubMed ID: 20045091
DOI: 10.1016/j.actbio.2009.12.045
|
|
18873
Suhara Y, Wada A, Tachibana Y, Watanabe M, Nakamura K, Nakagawa K, Okano T.
Structure-activity relationships in the conversion of vitamin K analogues into menaquinone-4. Substrates essential to the synthesis of menaquinone-4 in cultured human cell lines
Bioorg Med Chem
2010
18(9):3116-24
PubMed ID: 20378364
DOI: 10.1016/j.bmc.2010.03.035
|
|
12865
Chen ZX, Takao Y, Wang WX, Matsubara T, Ren LM.
Surface characteristics and in vitro biocompatibility of titanium anodized in a phosphoric acid solution at different voltages
Biomed Mater
2009
4(6):065003
PubMed ID: 19880985
DOI: 10.1088/1748-6041/4/6/065003
|
|
12780
Ishizawa M, Matsunawa M, Adachi R, Uno S, Ikeda K, Masuno H, Shimizu M, Iwasaki K, Yamada S, Makishima M.
Lithocholic acid derivatives act as selective vitamin D receptor modulators without inducing hypercalcemia
J Lipid Res
2008
49(4):763-72.
PubMed ID: 18180267
DOI: 10.1194/jlr.M700293-JLR200
|
|
6661
Kamiyama F, Maeda T, Yamane T, Li YH, Ogukubo O, Otsuka T, Ueyama H, Takahashi S, Ohkubo I, Matsui N.
Inhibition of vitronectin-mediated haptotaxis and haptoinvasion of MG-63 cells by domain 5 (D5(H)) of human high-molecular-weight kininogen and identification of a minimal amino acid sequence.
Biochem Biophys Res Commun
2001
288(4):975-80
PubMed ID: 11689005
DOI: 10.1006/bbrc.2001.5864
|
戻る
細胞材料の再培養方法 (
HPS以外・
HPS )
ページトップへ
細胞材料開発室サイト