利用者成果(英) |
19845
Uchida Y, Ferdousi F, Takahashi S, Isoda H.
Comprehensive Transcriptome Profiling of Antioxidant Activities by Glutathione in Human HepG2 Cells
Molecules
2024
29(5):1090
PubMed ID: 38474603
DOI: 10.3390/molecules29051090
|
19882
Kaito S, Takeshita JI, Iwata M, Sasaki T, Hosaka T, Shizu R, Yoshinari K.
Utility of human cytochrome P450 inhibition data in the assessment of drug-induced liver injury
Xenobiotica
2024
1-30
PubMed ID: 38315106
DOI: 10.1080/00498254.2024.2312505
|
19985
Shimura M, Higashi-Kuwata N, Fujiwara A, Taniguchi M, Ichinose T, Hamano F, Uematsu M, Inoue T, Matsuyama S, Suzuki T, Ghosh AK, Shindou H, Shimuzu T, Mitsuya H.
A lipid index for risk of hyperlipidemia caused by anti-retroviral drugs
Antiviral Res
2024
3:223:105819
PubMed ID: 38272319
DOI: 10.1016/j.antiviral.2024.105819
|
21713
Furuno K, Suzuki K, Sakai S.
Transduction and Genome Editing of the Heart with Adeno-Associated Viral Vectors Loaded onto Electrospun Polydioxanone Nonwoven Fabrics.
Biomolecules
2024
14(4)
PubMed ID: 38672522
DOI: 10.3390/biom14040506
|
21943
Yanagisawa H, Maeda H, Noguchi I, Tanaka M, Wada N, Nagasaki T, Kobayashi K, Kanazawa G, Taguchi K, Chuang VTG, Sakai H, Nakashima H, Kinoshita M, Kitagishi H, Iwakiri Y, Sasaki Y, Tanaka Y, Otagiri M, Watanabe H, Maruyama T.
Carbon monoxide-loaded red blood cells ameliorate metabolic dysfunction-associated steatohepatitis progression via enhancing AMP-activated protein kinase activity and inhibiting Kupffer cell activation.
Redox Biol
2024
76:103314
PubMed ID: 39163766
DOI: 10.1016/j.redox.2024.103314
|
21944
Ogiwara N, Nakano T, Baba K, Noguchi H, Masuda T, Takai M.
High-Quality Three-Dimensionally Cultured Cells Using Interfaces of Diblock Copolymers Containing Different Ratios of Zwitterionic N-Oxides.
ACS Appl Mater Interfaces
2024
PubMed ID: 39160767
DOI: 10.1021/acsami.4c10118
|
21949
Sato T, Shizu R, Baba R, Ooka A, Hosaka T, Kanno Y, Yoshinari K.
Pregnane X receptor inhibits the transdifferentiation of hepatic stellate cells by downregulating periostin expression.
Biochem J
2024
PubMed ID: 39171361
DOI: 10.1042/BCJ20240172
|
21972
Ogawa T, Terada T.
The Beneficial Effect of Brazilian Propolis for Liver Damage through Endoplasmic Reticulum Stress
Biol Pharm Bull
2024
47(7):1265-1274
PubMed ID: 38987175
DOI: 10.1248/bpb.b24-00092
|
21991
Kasano-Camones CI, Yokota S, Ohashi M, Sakamoto N, Ito D, Saito Y, Uchida R, Ninomiya K, Inoue Y.
Hepatocyte nuclear factor 4α is a critical factor for the production of complement components in the liver.
In Vitro Cell Dev Biol Anim
2024
PubMed ID: 39285151
DOI: 10.1007/s11626-024-00972-6
|
21992
Mitsutani M, Yokoyama M, Hano H, Morita A, Matsushita M, Tagami T, Moriyama K.
Growth hormone is involved in GATA1 gene expression via STAT5B in human erythroleukemia and monocytic cell lines.
Blood Cells Mol Dis
2024
110:102894
PubMed ID: 39303396
DOI: 10.1016/j.bcmd.2024.102894
|
22012
Adachi M, Kumagai T, Hosho K, Nagata K, Fujiyoshi M, Shimada M.
Exploring Acute Liver Damage: Slimming Health Foods and CYP3A4 Induction.
Yonago Acta Med
2024
67(2):124-134
PubMed ID: 38803590
DOI: 10.33160/yam.2024.05.004
|
22023
Okami K, Fumoto S, Yamashita M, Nakashima M, Miyamoto H, Kawakami S, Nishida K.
One-Step Formation Method of Plasmid DNA-Loaded, Extracellular Vesicles-Mimicking Lipid Nanoparticles Based on Nucleic Acids Dilution-Induced Assembly.
Cells
2024
13(14):
PubMed ID: 39056764
DOI: 10.3390/cells13141183
|
19583
Tabei Y, Abe H, Suzuki S, Takeda N, Arai JI, Nakajima Y.
Sedanolide Activates KEAP1-NRF2 Pathway and Ameliorates Hydrogen Peroxide-Induced Apoptotic Cell Death
Int J Mol Sci
2023
24(22):16532
PubMed ID: 38003720
DOI: 10.3390/ijms242216532
|
19652
oko Takeo, Kai Sakurai, Noboru Furuya, Kyota Yoshinaga, Takenori Shimamura, Satoru Egawa, Hisao Kiuchi, Hidekazu Mimura, Haruhiko Ohashi, Yoshihisa Harada, Mari Shimura, Takashi Kimura
Development of soft X-ray ptychography and fluorescence microscopy system using total-reflection wolter mirror and application to measurement of drug-treated mammalian cells
Journal of Electron Spectroscopy and Related Phenomena
2023
237:147380
DOI: 10.1016/j.elspec.2023.147380
|
19659
Goto R, Nakahata M, Delattre C, Petit E, El Boutachfaiti R, Sakai S.
Fabrication of cell-laden microbeads and microcapsules composed of bacterial polyglucuronic acid
Int J Biol Macromol
2023
244:125481
PubMed ID: 37343612
DOI: 10.1016/j.ijbiomac.2023.125481
|
19663
Kotani T, Mubarok W, Hananouchi T, Sakai S.
Horseradish Peroxidase-Mediated Bioprinting via Bioink Gelation by Alternately Extruded Support Material
ACS Biomater Sci Eng
2023
9(10):5804-5812
PubMed ID: 37738620
DOI: 10.1021/acsbiomaterials.3c00996
|
19800
Hori M, Takahashi A, Hosoda K, Ogura M, Harada-Shiba M.
A Low-Frequency APOB p.(Pro955Ser) Variant Contributes to the Severity of/Variability in Familial Hypercholesterolemia
J Clin Endocrinol Metab
2023
108(2):422-432
PubMed ID: 36190978
DOI: 10.1210/clinem/dgac572
|
19810
Sekiguchi M, Fujinami Y, Takado K, Kimoto Y, Higashimura Y.
Activity difference of three labdane diterpenoids on human constitutive androstane receptor
Biosci Biotechnol Biochem
2023
87(11):1310-1315
PubMed ID: 37580155
DOI: 10.1093/bbb/zbad113
|
19821
Liu S, Morihiro K, Takeuchi F, Li Y, Okamoto A.
Interstrand crosslinking oligonucleotides elucidate the effect of metal ions on the methylation status of repetitive DNA elements
Front Chem
2023
11:1122474
PubMed ID: 36711237
DOI: 10.3389/fchem.2023.1122474
|
19846
Takagi M, Yamada M, Utoh R, Seki M.
A multiscale, vertical-flow perfusion system with integrated porous microchambers for upgrading multicellular spheroid culture
Lab Chip
2023
23(9):2257-2267
PubMed ID: 37038847
DOI: 10.1039/d3lc00168g
|
19919
Wuputra K, Tsai MH, Kato K, Ku CC, Pan JB, Yang YH, Saito S, Wu CC, Lin YC, Cheng KH, Kuo KK, Noguchi M, Nakamura Y, Yoshioka T, Wu DC, Lin CS, Yokoyama KK.
Jdp2 is a spatiotemporal transcriptional activator of the AhR via the Nrf2 gene battery
Inflamm Regen
2023
43(1):42
PubMed ID: 37596694
DOI: 10.1186/s41232-023-00290-6
|
19948
Ota K, Sakai S, Ohhata T, Suzuki T, Uchida C, Niida H, Kitagawa M.
APOBEC3B expression is promoted by lincNMR collaborating with TGF-β-Smad pathway
Carcinogenesis
2023
44(1):1-14
PubMed ID: 36335471
DOI: 10.1093/carcin/bgac086
|
19960
Nakano M, Sakamoto T, Kitano Y, Bono H, Simpson RJ, Tabunoki H.
An extract from the frass of swallowtail butterfly (Papilio machaon) larvae inhibits HCT116 colon cancer cell proliferation but not other cancer cell types
BMC Genomics
2023
24(1):735
PubMed ID: 38049715
DOI: 10.1186/s12864-023-09841-0
|
21073
Matsuo K, Abiko Y, Yamano S, Toriba A, Matsusue K, Kumagai Y.
Activation of the Keap1/Nrf2 Pathway as an Adaptive Response to an Electrophilic Metabolite of Morphine.
Biol Pharm Bull
2023
46(2):338-342
PubMed ID: 36724962
DOI: 10.1248/bpb.b22-00543
|
21074
Matsuo K, Abiko Y, Yamano S, Matsusue K, Kumagai Y.
Activation of HSP90/HSF1 Signaling as an Adaptive Response to an Electrophilic Metabolite of Morphine.
Biol Pharm Bull
2023
46(2):334-337
PubMed ID: 36724961
DOI: 10.1248/bpb.b22-00531
|
21276
Mubarok W, Elvitigala KCML, Kotani T, Sakai S.
Visible light photocrosslinking of sugar beet pectin for 3D bioprinting applications.
Carbohydr Polym
2023
316:121026
PubMed ID: 37321724
DOI: 10.1016/j.carbpol.2023.121026
|
17493
Yamazaki K, Matsuo K, Okada A, Uno N, Suzuki T, Abe S, Hamamichi S, Kishima N, Togai S, Tomizuka K, Kazuki Y.
Simultaneous loading of PCR-based multiple fragments on mouse artificial chromosome vectors in DT40 cell for gene delivery
Sci Rep
2022
12(1):21790
PubMed ID: 36526651
DOI: 10.1038/s41598-022-25959-9
|
17512
amamoto H, Yoshida N, Kihara S.
Esaxerenone Blocks Vascular Endothelial Inflammation Through SGK1
J Cardiovasc Pharmacol
2022
80(4):583-591
PubMed ID: 35900901
DOI: 10.1097/FJC.0000000000001316
|
17594
Akiyama M, Shinkai Y, Yamakawa H, Kim YG, Kumagai Y.
Potentiation of methylmercury toxicity by combined metal exposure: In vitro and in vivo models of a restricted metal exposome
Chemosphere
2022
299:134374
PubMed ID: 35318019
DOI: 10.1016/j.chemosphere.2022.134374
|
17669
Kamiya M, Matsumoto M, Yamashita K, Izumi T, Kawaguchi M, Mizukami S, Tsurumaru M, Mukai H, Kawakami S.
Stability Study of mRNA-Lipid Nanoparticles Exposed to Various Conditions Based on the Evaluation between Physicochemical Properties and Their Relation with Protein Expression Ability
Pharmaceutics
2022
14(11):2357
PubMed ID: 36365175
DOI: 10.3390/pharmaceutics14112357
|
17788
Takeuchi Y, Ushimaru K, Kaneda K, Maruyama C, Ito T, Yamanaka K, Ogasawara Y, Katano H, Kato Y, Dairi T, Hamano Y.
First direct evidence for direct cell-membrane penetrations of polycationic homopoly(amino acid)s produced by bacteria
Commun Biol
2022
5(1):1132
PubMed ID: 36289442
DOI: 10.1038/s42003-022-04110-4
|
19530
Hu D, Fumoto S, Miyamoto H, Tanaka M, Nishida K.
Flavonoids Enhance Lipofection Efficiency and Ameliorate Cytotoxicity in Colon26 and HepG2 Cells via Oxidative Stress Regulation
Pharmaceutics
2022
14(6):1203
PubMed ID: 35745776
DOI: 10.3390/pharmaceutics14061203
|
20483
Koide R, Hirane N, Kambe D, Yokoi Y, Otaki M, Nishimura SI.
Antiadhesive nanosome elicits role of glycocalyx of tumor cell-derived exosomes in the organotropic cancer metastasis.
Biomaterials
2022
280:121314
PubMed ID: 34906850
DOI: 10.1016/j.biomaterials.2021.121314
|
16114
Wuputra K, Tsai MH, Kato K, Yang YH, Pan JB, Ku CC, Noguchi M, Kishikawa S, Nakade K, Chen HL, Liu CJ, Nakamura Y, Kuo KK, Lin YC, Chan TF, Wu DC, Hou MF, Huang SK, Lin CS, Yokoyama KK.
Dimethyl sulfoxide stimulates the AhR-Jdp2 axis to control ROS accumulation in mouse embryonic fibroblasts
Cell Biol Toxicol
2022
Mar 15
PubMed ID: 33723743
DOI: 10.1007/s10565-021-09592-2
|
16273
Sakai S, Kotani T, Harada R, Goto R, Morita T, Bouissil S, Dubessay P, Pierre G, Michaud P, El Boutachfaiti R, Nakahata M, Kojima M, Petit E, Delattre C.
Development of phenol-grafted polyglucuronic acid and its application to extrusion-based bioprinting inks
Carbohydr Polym
2022
277:118820
PubMed ID: 34893237
DOI: 10.1016/j.carbpol.2021.118820
|
20613
Shimmyo N, Furuhata M, Yamada M, Utoh R, Seki M.
Process simplification and structure design of parallelized microslit isolator for physical property-based capture of tumor cells.
Analyst
2022
PubMed ID: 35297918
DOI: 10.1039/d2an00052k
|
20657
Fukumoto Y, Matsuhashi K, Tanaka YK, Suzuki N, Ogra Y.
Band 3/anion exchanger 1/solute carrier family 4 member 1 expression as determinant of cellular sensitivity to selenite exposure.
Biochem Biophys Rep
2022
29:101223
PubMed ID: 35146136
DOI: 10.1016/j.bbrep.2022.101223
|
20752
Shindo S, Shioya A, Watanabe M, Sasaki T, Suzuki H, Kumagai T, Hwang GW, Nagata K.
Development of an adenovirus-mediated reporter assay system to detect a low concentration of retinoic acid in MCF-7 cells.
J Toxicol Sci
2022
47(6):249-255
PubMed ID: 35650141
DOI: 10.2131/jts.47.249
|
20753
Luong NC, Abiko Y, Aoki H, Kumagai Y.
A Convenient Assay to Detect Protein Oxidation Caused by Redox-Active Quinones.
Biol Pharm Bull
2022
45(6):798-802
PubMed ID: 35650106
DOI: 10.1248/bpb.b22-00080
|
16739
Hori K, Higashida S, Osaki T, Kawano T, Inaba H, Matsuura K, Iwasaki T.
Intracellular delivery and photothermal therapeutic effects of polyhistidine peptide-modified gold nanoparticles
J Biotechnol
2022
354:34-44
PubMed ID: 35724765
DOI: 10.1016/j.jbiotec.2022.06.006
|
20784
Abiko Y, Taguchi K, Hisamori M, Hiyoshi-Arai K, Luong NC, Toriba A, Kumagai Y.
Redox Homeostasis is Disturbed by Redox Cycling between Reactive Cysteines of Thioredoxin 1 and 9,10-Phenanthrenequinone, an Atmospheric Electron Acceptor.
Chem Res Toxicol
2022
PubMed ID: 35862866
DOI: 10.1021/acs.chemrestox.2c00174
|
16971
Kawase A, Takashima O, Tanaka S, Shimada H, Iwaki M.
Diclofenac-Induced Cytotoxicity in Direct and Indirect Co-Culture of HepG2 Cells with Differentiated THP-1 Cells
Int J Mol Sci
2022
23(15):8660
PubMed ID: 35955793
DOI: 10.3390/ijms23158660
|
20862
Tachikawa R, Saito H, Moteki H, Kimura M, Kitagishi H, Arce F Jr, See GL, Tanikawa T, Inoue Y.
Preparation, Characterization, and In Vitro Evaluation of Inclusion Complexes Formed between S-Allylcysteine and Cyclodextrins.
ACS Omega
2022
7(35):31233-31245
PubMed ID: 36092555
DOI: 10.1021/acsomega.2c03489
|
20947
Ishida-Ishihara S, Takada R, Furusawa K, Ishihara S, Haga H.
Improvement of the cell viability of hepatocytes cultured in three-dimensional collagen gels using pump-free perfusion driven by water level difference.
Sci Rep
2022
12(1):20269
PubMed ID: 36434099
DOI: 10.1038/s41598-022-24423-y
|
17333
Inaba H, Sueki Y, Ichikawa M, Kabir AMR, Iwasaki T, Shigematsu H, Kakugo A, Sada K, Tsukazaki T, Matsuura K.
Generation of stable microtubule superstructures by binding of peptide-fused tetrameric proteins to inside and outside
Sci Adv
2022
8(36):eabq3817
PubMed ID: 36070375
DOI: 10.1126/sciadv.abq3817
|
20997
Kawaguchi M, Noda M, Ono A, Kamiya M, Matsumoto M, Tsurumaru M, Mizukami S, Mukai H, Kawakami S.
Effect of Cholesterol Content of Lipid Composition in mRNA-LNPs on the Protein Expression in the Injected Site and Liver After Local Administration in Mice.
J Pharm Sci
2022
PubMed ID: 36596392
DOI: 10.1016/j.xphs.2022.12.026
|
21019
Kazama R, Fujita S, Sakai S.
Cell Dome as an Evaluation Platform for Organized HepG2 Cells.
Cells
2022
PubMed ID: 36611862
DOI: 10.3390/cells12010069
|
21983
Hu X, Roy SR, Jin C, Li G, Zhang Q, Asano N, Asahina S, Kajiwara T, Takahara A, Feng B, Aoki K, Xu C, Zhang Y.
Control cell migration by engineering integrin ligand assembly.
Nat Commun
2022
13(1):5002
PubMed ID: 36008449
DOI: 10.1038/s41467-022-32686-2
|
13179
Hayakawa EH, Kato H, Nardone GA, Usukura J.
A prospective mechanism and source of cholesterol uptake by Plasmodium falciparum-infected erythrocytes co-cultured with HepG2 cells.
Parasitol Int
2021
PubMed ID: 32853776
DOI: 10.1016/j.parint.2020.102179
|
13396
Yanagimichi M, Nishino K, Sakamoto A, Kurodai R, Kojima K, Eto N, Isoda H, Ksouri R, Irie K, Kambe T, Masuda S, Akita T, Maejima K, Nagao M.
Analyses of putative anti-cancer potential of three STAT3 signaling inhibitory compounds derived from Salvia officinalis.
Biochem Biophys Rep
2021
PubMed ID: 33392396
DOI: 10.1016/j.bbrep.2020.100882
|
13418
Abiko Y, Aoki H, Kumagai Y.
Effect of combined exposure to environmental aliphatic electrophiles from plants on Keap1/Nrf2 activation and cytotoxicity in HepG2 cells: A model of an electrophile exposome.
Toxicol Appl Pharmacol
2021
PubMed ID: 33428920
DOI: 10.1016/j.taap.2020.115392
|
20024
Yamazaki T, Tokiwa T.
Elevated levels of expression of cytochrome P450 3A4 in a human liver epithelial cell line in differentiation-inducing conditions.
Hum Cell
2021
PubMed ID: 33495943
DOI: 10.1007/s13577-021-00487-2
|
20049
Abiko Y, Katayama Y, Akiyama M, Kumagai Y.
Lipophilic compounds in garlic decrease the toxicity of methylmercury by forming sulfur adducts.
Food Chem Toxicol
2021
150:112061
PubMed ID: 33587975
DOI: 10.1016/j.fct.2021.112061
|
20081
Tokuda K, Morine Y, Miyazaki K, Yamada S, Saito Y, Nishi M, Tokunaga T, Ikemoto T, Imura S, Shimada M.
The interaction between cancer associated fibroblasts and tumor associated macrophages via the osteopontin pathway in the tumor microenvironment of hepatocellular carcinoma.
Oncotarget
2021
12(4):333-343
PubMed ID: 33659044
DOI: 10.18632/oncotarget.27881
|
20119
Mao Q, Kawaguchi AT, Mizobata S, Motterlini R, Foresti R, Kitagishi H.
Sensitive quantification of carbon monoxide in vivo reveals a protective role of circulating hemoglobin in CO intoxication.
Commun Biol
2021
4(1):425
PubMed ID: 33782534
DOI: 10.1038/s42003-021-01880-1
|
20166
Yugawa K, Itoh S, Yoshizumi T, Iseda N, Tomiyama T, Morinaga A, Toshima T, Harada N, Kohashi K, Oda Y, Mori M.
CMTM6 Stabilizes PD-L1 Expression and Is a New Prognostic Impact Factor in Hepatocellular Carcinoma.
Hepatol Commun
2021
5(2):334-348
PubMed ID: 33553979
DOI: 10.1002/hep4.1643
|
20204
Soeta K, Yamaguchi R, Iuchi K, Hisatomi H, Yokoyama C.
Generation of Rat Monoclonal Antibody for Human IQGAP1 by Immunization of Three-Dimensional-Cultured Cancer Cells.
Monoclon Antib Immunodiagn Immunother
2021
40(3):118-123
PubMed ID: 34076498
DOI: 10.1089/mab.2020.0046
|
20281
Liu WY, Miyakawa T, Lu J, Hsieh YH, Gu R, Miyauchi Y, Katsuno K, Cai MY, Tanokura M.
Isolation and characterization of oligopeptides with vascular disease suppression effects derived from wheat gluten.
J Food Sci Technol
2021
58(9):3504-3513
PubMed ID: 34366467
DOI: 10.1007/s13197-021-05040-5
|
20288
Iwado S, Abe S, Oshimura M, Kazuki Y, Nakajima Y.
Bioluminescence Measurement of Time-Dependent Dynamic Changes of CYP-Mediated Cytotoxicity in CYP-Expressing Luminescent HepG2 Cells.
Int J Mol Sci
2021
22(6)
PubMed ID: 33799598
DOI: 10.3390/ijms22062843
|
20384
Fujita I, Watanabe H, Ikegami K, Imafuku T, Ichimizu S, Chikamatsu M, Kobayashi K, Tanaka R, Yamada K, Maeda H, Maruyama T.
Involvement of the Parathyroid Hormone-Related Protein on Changes in the CYP3A Expression in Cancer Cachexia.
Mol Pharm
2021
PubMed ID: 34734526
DOI: 10.1021/acs.molpharmaceut.1c00490
|
20502
Shizu R, Ezaki K, Sato T, Sugawara A, Hosaka T, Sasaki T, Yoshinari K.
PXR Suppresses PPARα-Dependent HMGCS2 Gene Transcription by Inhibiting the Interaction between PPARα and PGC1α.
Cells
2021
10(12)
PubMed ID: 34944058
DOI: 10.3390/cells10123550
|
16100
Ogawa S, Kubo H, Murayama Y, Kubota T, Yubakami M, Matsumoto T, Yamamoto Y, Morimura R, Ikoma H, Okamoto K, Kamiya M, Urano Y, Otsuji E.
Rapid fluorescence imaging of human hepatocellular carcinoma using the β-galactosidase-activatable fluorescence probe SPiDER-βGal
Sci Rep
2021
11(1):1794
PubMed ID: 34504174
DOI: 10.1038/s41598-021-97073-1
|
16205
Ishida K, Kaji K, Sato S, Ogawa H, Takagi H, Takaya H, Kawaratani H, Moriya K, Namisaki T, Akahane T, Yoshiji H.
Sulforaphane ameliorates ethanol plus carbon tetrachloride-induced liver fibrosis in mice through the Nrf2-mediated antioxidant response and acetaldehyde metabolization with inhibition of the LPS/TLR4 signaling pathway
J Nutr Biochem
2021
89:108573
PubMed ID: 33388347
DOI: 10.1016/j.jnutbio.2020.108573
|
16370
Enokiya T, Nishikawa K, Hamada Y, Ikemura K, Sugimura Y, Okuda M.
Temporary decrease in tacrolimus clearance in cytochrome P450 3A5 non-expressors early after living donor kidney transplantation: Effect of interleukin 6-induced suppression of the cytochrome P450 3A gene
Basic Clin Pharmacol Toxicol
2021
128(3):525-533
PubMed ID: 33248001
DOI: 10.1111/bcpt.13539
|
16372
Yoshitaka Koseki, Yoshikazu Ikuta, Farsai Taemaitree, Nozomi Saito, Ryuju Suzuki, Anh Thi Ngoc Dao, Tsunenobu Onodera, Hidetoshi Oikawa, Hitoshi Kasai
Fabrication of size-controlled SN-38 pure drug nanocrystals through an ultrasound-assisted reprecipitation method toward efficient drug delivery for cancer treatment
Journal of Crystal Growth
2021
572:126265
DOI: 10.1016/j.jcrysgro.2021.126265
|
20621
Kodama S, Yoshii N, Ota A, Takeshita JI, Yoshinari K, Ono A.
Association between in vitro nuclear receptor-activating profiles of chemical compounds and their in vivo hepatotoxicity in rats.
J Toxicol Sci
2021
46(12):569-587
PubMed ID: 34853243
DOI: 10.2131/jts.46.569
|
22038
Taguchi T, Kodera Y, Oba K, Saito T, Nakagawa Y, Kawashima Y, Shichiri M.
Suprabasin-derived bioactive peptides identified by plasma peptidomics.
Sci Rep
2021
PubMed ID: 33441610
DOI: 10.1038/s41598-020-79353-4
|
19253
Wen-Ying Liu, Takuya Miyakawa, Jun Lu, Rui-Zeng Gu, Yun Hua Hsieh, Yumiko Miyauchi, Kana Katsuno, Mu-Yi Cai, Masaru Tanokura
Low-molecular-weight peptides with potential cardiovascular regulatory functions from Atlantic salmon skin
International Journal of Food Engineering
2020
16
DOI: 10.1515/ijfe-2020-0072
|
12030
Yoshizawa N, Sugimoto K, Tameda M, Inagaki Y, Ikejiri M, Inoue H, Usui M, Ito M, Takei Y.
miR-3940-5p/miR-8069 ratio in urine exosomes is a novel diagnostic biomarker for pancreatic ductal adenocarcinoma.
Oncol Lett
2020
PubMed ID: 32218818
DOI: 10.3892/ol.2020.11357
|
12057
Seyama M, Yoshida K, Yoshida K, Fujiwara N, Ono K, Eguchi T, Kawai H, Guo J, Weng Y, Haoze Y, Uchibe K, Ikegame M, Sasaki A, Nagatsuka H, Okamoto K, Okamura H, Ozaki K.
Outer membrane vesicles of Porphyromonas gingivalis attenuate insulin sensitivity by delivering gingipains to the liver.
Biochim Biophys Acta Mol Basis Dis
2020
PubMed ID: 32088316
DOI: 10.1016/j.bbadis.2020.165731
|
12094
Hori T, Kurosawa O, Ishihara K, Mizuta T, Iwata H.
Three-Dimensional Cell Sheet Construction Method with a Polyester Micromesh Sheet.
Tissue Eng Part C Methods
2020
PubMed ID: 32186996
DOI: 10.1089/ten.tec.2019.0330
|
12198
Hiroki Inada, Miyako Udono, Kanae Matsuda-Ito, Kenichi Horisawa, Yasuyuki Ohkawa, Shizuka Miura, Takeshi Goya, Junpei Yamamoto, Masao Nagasaki, Kazuko Ueno, Daisuke Saitou, Mikita Suyama, Yoshihiko Maehara, Wataru Kumamaru, Yoshihiro Ogawa, Sayaka Sekiya, Atsushi Suzuki
Direct reprogramming of human umbilical vein- and peripheral blood-derived endothelial cells into hepatic progenitor cells
Nature Communications
2020
11:5292
PubMed ID: 33087715
DOI: 10.1038/s41467-020-19041-z
|
12439
Fujiyama Y, Kumamoto Y, Nishizawa N, Nakamoto S, Harada H, Yokota K, Tanaka Y, Igarashi K, Oiki H, Okuwaki K, Iwai T, Kajita S, Takahashi H, Tajima H, Kaizu T, Sasaki J, Watanabe M, Yamashita K.
Promoter DNA Hypermethylation of the Cysteine Dioxygenase 1 (CDO1) Gene in Intraductal Papillary Mucinous Neoplasm (IPMN)
Ann Surg Oncol
2020
27(10):4007-4016
PubMed ID: 32144623
DOI: 10.1245/s10434-020-08291-2
|
12963
Saeki K, Hiramatsu H, Hori A, Hirai Y, Yamada M, Utoh R, Seki M.
Sacrificial Alginate-Assisted Microfluidic Engineering of Cell-Supportive Protein Microfibers for Hydrogel-Based Cell Encapsulation.
ACS Omega
2020
PubMed ID: 32905425
DOI: 10.1021/acsomega.0c02385
|
13027
Hirano T, Hirata M, Fujimoto S, Nguyen NT, Le QA, Tanihara F, Otoi T.
Comparative analysis of bilirubin glucuronidation activity in 2D- and 3D-cultured human hepatocellular carcinoma HepG2 cells.
In Vitro Cell Dev Biol Anim
2020
PubMed ID: 32394241
DOI: 10.1007/s11626-020-00451-8
|
13036
Tanaka M, Sato A, Kishimoto Y, Mabashi-Asazuma H, Kondo K, Iida K.
Gallic Acid Inhibits Lipid Accumulation via AMPK Pathway and Suppresses Apoptosis and Macrophage-Mediated Inflammation in Hepatocytes.
Nutrients
2020
PubMed ID: 32443660
DOI: 10.3390/nu12051479
|
13053
Kim DH, Kim WD, Kim SK, Moon DH, Lee SJ.
TGF-β1-mediated repression of SLC7A11 drives vulnerability to GPX4 inhibition in hepatocellular carcinoma cells.
Cell Death Dis
2020
PubMed ID: 32471991
DOI: 10.1038/s41419-020-2618-6
|
13073
Teratani T, Tomita K, Toma-Fukai S, Nakamura Y, Itoh T, Shimizu H, Shiraishi Y, Sugihara N, Higashiyama M, Shimizu T, Inoue I, Takenaka Y, Hokari R, Adachi T, Shimizu T, Miura S, Kanai T.
Redox-dependent PPARγ/Tnpo1 complex formation enhances PPARγ nuclear localization and signaling.
Free Radic Biol Med
2020
PubMed ID: 32553752
DOI: 10.1016/j.freeradbiomed.2020.06.005
|
13103
Sekiguchi M, Seki M, Kawai T, Yoshida K, Yoshida M, Isobe T, Hoshino N, Shirai R, Tanaka M, Souzaki R, Watanabe K, Arakawa Y, Nannya Y, Suzuki H, Fujii Y, Kataoka K, Shiraishi Y, Chiba K, Tanaka H, Shimamura T, Sato Y, Sato-Otsubo A, Kimura S, Kubota Y, Hiwatari M, Koh K, Hayashi Y, Kanamori Y, Kasahara M, Kohashi K, Kato M, Yoshioka T, Matsumoto K, Oka A, Taguchi T, Sanada M, Tanaka Y, Miyano S, Hata K, Ogawa S, Takita J.
Integrated multiomics analysis of hepatoblastoma unravels its heterogeneity and provides novel druggable targets.
NPJ Precis Oncol
2020
PubMed ID: 32656360
DOI: 10.1038/s41698-020-0125-y
|
13189
Abiko Y, Okada M, Aoki H, Mizokawa M, Kumagai Y.
A strategy for repression of arsenic toxicity through nuclear factor E2 related factor 2 activation mediated by the (E)-2-alkenals in Coriandrum sativum L. leaf extract.
Food Chem Toxicol
2020
PubMed ID: 32871193
DOI: 10.1016/j.fct.2020.111706
|
13191
Xu DQ, Yuan XJ, Hirayama M, Toyoda H.
Huaier Extract Induces Apoptosis in Hepatoblastoma Cells Via the MEK/ERK Signaling Pathway.
In Vivo
2020
PubMed ID: 32871763
DOI: 10.21873/invivo.12051
|
13241
Yamashita R, Komaki Y, Yang G, Ibuki Y.
Cell line-dependent difference in glutathione levels affects the cigarette sidestream smoke-induced inhibition of nucleotide excision repair.
Mutat Res
2020
PubMed ID: 33198939
DOI: 10.1016/j.mrgentox.2020.503273
|
13290
Nakane W, Nakamura H, Nakazato T, Kaminaga N, Nakano M, Sakamoto T, Nishiko M, Bono H, Ogiwara I, Kitano Y, Iwabuchi K, Kinoshita K, Simpson RJ, Tabunoki H.
Construction of TUATinsecta database that integrated plant and insect database for screening phytophagous insect metabolic products with medicinal potential.
Sci Rep
2020
PubMed ID: 33060804
DOI: 10.1038/s41598-020-74590-z
|
13528
Ishizawa K, Togami K, Tada H, Chono S.
Multiscale Live Imaging Using Förster Resonance Energy Transfer (FRET) for Evaluating the Biological Behavior of Nanoparticles as Drug Carriers
J Pharm Sci
2020
109(12):3608-3616
PubMed ID: 32926888
DOI: 10.1016/j.xphs.2020.08.028
|
13635
Taniguchi M, Miyamoto H, Tokunaga A, Fumoto S, Tanaka T, Nishida K.
Evaluation of mRNA expression of drug-metabolizing enzymes in acetaminophen-induced hepatotoxicity using a three-dimensional hepatocyte culture system
Xenobiotica
2020
50(6):654-662
PubMed ID: 31631733
DOI: 10.1080/00498254.2019.1683258
|
14866
Tajiri A, Hirota T, Kawano S, Yonamine A, Ieiri I.
Regulation of Organic Anion Transporting Polypeptide 2B1 Expression by MicroRNA in the Human Liver
Mol Pharm
2020
17(8):2821-2830
PubMed ID: 32602343
DOI: 10.1021/acs.molpharmaceut.0c00193
|
5027
Nishizawa N1, Harada H1, Kumamoto Y1, Kaizu T, Katoh H, Tajima H, Ushiku H, Yokoi K, Igarashi K, Fujiyama Y, Okuwaki K, Iwai T, Watanabe M, Yamashita K1
Diagnostic potential of hypermethylation of the cysteine dioxygenase 1 gene (CDO1) promoter DNA in pancreatic cancer.
Cancer Sci
2019
110(9):2846-2855
PubMed ID: 31325200
DOI: 10.1111/cas.14134
|
5357
Takahashi D, Moriyama J, Nakamura T, Miki E, Takahashi E, Sato A, Akaike T, Itto-Nakama K, Arimoto H.
AUTACs: Cargo-Specific Degraders Using Selective Autophagy.
Mol Cell
2019
76(5):797-810
PubMed ID: 31606272
DOI: 10.1016/j.molcel.2019.09.009
|
11522
Li M, Cui ZG, Zakki SA, Feng Q, Sun L, Feril LB Jr, Inadera H.
Aluminum chloride causes 5-fluorouracil resistance in hepatocellular carcinoma HepG2 cells.
J. Cell. Physiol.
2019
PubMed ID: 30993729
DOI: 10.1002/jcp.28625
|
11538
Maehara O, Ohnishi S, Asano A, Suda G, Natsuizaka M, Nakagawa K, Kobayashi M, Sakamoto N, Takeda H.
Metformin Regulates the Expression of CD133 Through the AMPK-CEBPβ Pathway in Hepatocellular Carcinoma Cell Lines.
Neoplasia
2019
PubMed ID: 31042624
DOI: 10.1016/j.neo.2019.03.007
|
11857
Utsugi Y, Kobuchi H, Kawamura Y, Atito ASA, Nagao M, Isoda H, Miyamae Y.
Importance of the Proximity and Orientation of Ligand-Linkage to the Design of Cinnamate-GW9662 Hybrid Compounds as Covalent PPARγ Agonists.
Molecules
2019
PubMed ID: 31137814
DOI: 10.3390/molecules24102019
|
6837
Bouallagui Z, Mahmoudi A, Maalej A, Hadrich F, Isoda H, Sayadi S.
Contribution of Major Polyphenols to the Antioxidant Profile and Cytotoxic Activity of Olive Leaves.
Anticancer Agents Med Chem
2019
19(13):1651-1657
PubMed ID: 31038081
DOI: 10.2174/1871520619666190416101622
|
9758
Hiromasa Fujita, Katsumi Hirose, Mariko Sato, Ichitaro Fujioka, Tamaki Fujita, Masahiko Aoki, Yoshihiro Takai
Metformin Attenuates Hypoxia-Induced Resistance to Cisplatin in the HepG2 Cell Line
Oncol Lett
2019
17(2):2431-2440
PubMed ID: 30719114
DOI: 10.3892/ol.2018.9869
|
9759
Tomoyuki Sato, Akinori Takemura, Yugo Ikeyama, Yuriko Sakamaki, Ayako Mimata, Haruyo Aoyagi, Hideki Aizaki, Shuichi Sekine, Kousei Ito
Transmission electron microscopy of the benzbromarone-induced change in mitochondrial morphology in HepG2 cells
Fundamental Toxicological Sciences
2019
6 :281-286
DOI: 10.2131/fts.6.281
|
9763
Kosuke Inamura, Yuji Komizu, Mami Yamakuchi, Seiichi Ishida, Yoko Matsumoto, Taku Matsushita
Inhibitory Effect of Hybrid Liposomes on the Growth of Liver Cancer Stem Cells
Biochem Biophys Res Commun
2019
509(1):268-274
PubMed ID: 30583860
DOI: 10.1016/j.bbrc.2018.12.118
|
11906
Kawase A, Inoue Y, Hirosoko M, Sugihara Y, Shimada H, Iwaki M.
Decrease in Multidrug Resistance-associated Protein 2 Activities by Knockdown of Phosphatidylinositol 4-phosphate 5-kinase in Hepatocytes and Cancer Cells.
J Pharm Pharm Sci
2019
PubMed ID: 31804920
DOI: 10.18433/jpps30444
|
11048
Yuta Kurashina, Ryo Sato, Hiroaki Onoe
Microfiber-shaped building-block tissues with endothelial networks for constructing macroscopic tissue assembly
APL Bioeng
2019
3(4):046101
PubMed ID: 31737859
DOI: 10.1063/1.5109966
|
11057
Kenji Ikemura, Shun-Ichi Hiramatsu, Yuri Shinogi, Yusuke Nakatani, Isao Tawara, Takuya Iwamoto, Naoyuki Katayama, Masahiro Okuda
Concomitant febuxostat enhances methotrexate-induced hepatotoxicity by inhibiting breast cancer resistance protein
Sci Rep
2019
9(1):20359
PubMed ID: 31889141
DOI: 10.1038/s41598-019-56900-2
|
12238
Ahmed Ali, Yasmine Abouleila, Yoshihiro Shimizu, Eiso Hiyama, Tomonobu M Watanabe, Toshio Yanagida, Arno Germond
Single-Cell Screening of Tamoxifen Abundance and Effect Using Mass Spectrometry and Raman-Spectroscopy
Anal Chem
2019
91(4):2710-2718
PubMed ID: 30664349
DOI: 10.1021/acs.analchem.8b04393
|
12365
Okamura M, Shizu R, Hosaka T, Sasaki T, Yoshinari K.
Possible involvement of the competition for the transcriptional coactivator glucocorticoid receptor-interacting protein 1 in the inflammatory signal-dependent suppression of PXR-mediated CYP3A induction in vitro
Drug Metab Pharmacokinet
2019
34(4):272-279
PubMed ID: 31280915
DOI: 10.1016/j.dmpk.2019.04.005
|
12443
Kojima K, Nakamura T, Ooizumi Y, Igarashi K, Tanaka T, Yokoi K, Ishii S, Nishizawa N, Katoh H, Kosaka Y, Sato T, Watanabe M, Yamashita K.
Clinical significance of cancer specific methylation of the CDO1 gene in small bowel cancer
PLoS One
2019
14(1):e0211108
PubMed ID: 30677088
DOI: 10.1371/journal.pone.0211108
|
12444
Oda-Yokouchi Y, Tachibana M, Iriko H, Torii M, Ishino T, Tsuboi T.
Plasmodium RON12 localizes to the rhoptry body in sporozoites
Parasitol Int
2019
68(1):17-23
PubMed ID: 30290224
DOI: 10.1016/j.parint.2018.10.001
|
12445
Hirama H, Satoh T, Sugiura S, Shin K, Onuki-Nagasaki R, Kanamori T, Inoue T.
Glass-based organ-on-a-chip device for restricting small molecular absorption
J Biosci Bioeng
2019
127(5):641-646
PubMed ID: 30473393
DOI: 10.1016/j.jbiosc.2018.10.019
|
12472
Hara M, Takeba Y, Iiri T, Ohta Y, Ootaki M, Watanabe M, Watanabe D, Koizumi S, Otsubo T, Matsumoto N.
Vasoactive intestinal peptide increases apoptosis of hepatocellular carcinoma by inhibiting the cAMP/Bcl-xL pathway
Cancer Sci
2019
110(1):235-244
PubMed ID: 30390393
DOI: 10.1111/cas.13861
|
12517
Satria D, Amen Y, Niwa Y, Ashour A, Allam AE, Shimizu K.
Lucidumol D, a new lanostane-type triterpene from fruiting bodies of Reishi (Ganoderma lingzhi)
Nat Prod Res
2019
33(2):189-195
PubMed ID: 29457741
DOI: 10.1080/14786419.2018.1440229
|
22043
Sarma SN, Nagano R, Ohsako S.
Tyroxine Hydroxylase-Positive Neuronal Cell Population is Increased by Temporal Dioxin Exposure at Early Stage of Differentiation from Human Embryonic Stem Cells.
Int J Mol Sci
2019
20(11)
PubMed ID: 31159217
DOI: 10.3390/ijms20112687
|
22044
Fujiyoshi J, Yamaza H, Sonoda S, Yuniartha R, Ihara K, Nonaka K, Taguchi T, Ohga S, Yamaza T.
Therapeutic potential of hepatocyte-like-cells converted from stem cells from human exfoliated deciduous teeth in fulminant Wilson's disease.
Sci Rep
2019
9(1):1535
PubMed ID: 30733544
DOI: 10.1038/s41598-018-38275-y
|
10634
Hara J, Tanaka Y, Kaneko H, Itoh Y, Ikegaya H.
Detection of hepatitis B virus DNA and HBsAg from postmortem blood and bloodstains.
Arch. Virol.
2018
163:633-637
PubMed ID: 29198036
DOI: 10.1007/s00705-017-3665-x
|
10641
Kaji K, Nishimura N, Seki K, Sato S, Saikawa S, Nakanishi K, Furukawa M, Kawaratani H, Kitade M, Moriya K, Namisaki T, Yoshiji H.
Sodium glucose cotransporter 2 inhibitor canagliflozin attenuates liver cancer cell growth and angiogenic activity by inhibiting glucose uptake.
Int. J. Cancer
2018
142:1712-1722
PubMed ID: 29205334
DOI: 10.1002/ijc.31193
|
10660
Darwish WS, Ikenaka Y, Nakayama S, Mizukawa H, Thompson LA, Ishizuka M.
β-carotene and retinol reduce benzo[a]pyrene-induced mutagenicity and oxidative stress via transcriptional modulation of xenobiotic metabolizing enzymes in human HepG2 cell line.
Environ Sci Pollut Res Int
2018
25:6320-6328
PubMed ID: 29247416
DOI: 10.1007/s11356-017-0977-z
|
10774
Yajima Y, Lee CN, Yamada M, Utoh R, Seki M.
Development of a perfusable 3D liver cell cultivation system via bundling-up assembly of cell-laden microfibers.
J. Biosci. Bioeng.
2018
126(1):111-118
PubMed ID: 29502942
DOI: 10.1016/j.jbiosc.2018.01.022
|
10786
He Q, Okajima T, Onoe H, Subagyo A, Sueoka K, Kuribayashi-Shigetomi K.
Origami-based self-folding of co-cultured NIH/3T3 and HepG2 cells into 3D microstructures.
Sci Rep
2018
8:4556
PubMed ID: 29540810
DOI: 10.1038/s41598-018-22598-x
|
10847
Kojima K, Nakamura T, Ohbu M, Katoh H, Ooizumi Y, Igarashi K, Ishii S, Tanaka T, Yokoi K, Nishizawa N, Yokota K, Kosaka Y, Sato T, Watanabe M, Yamashita K.
Cysteine dioxygenase type 1 (CDO1) gene promoter methylation during the adenoma-carcinoma sequence in colorectal cancer.
PLoS ONE
2018
13:e0194785
PubMed ID: 29746493
DOI: 10.1371/journal.pone.0194785
|
11025
Isolation of activating factors of serotonin N-acetyltransferase from rice peptides
Journal of Functional Foods
2018
41, 148-154
DOI: 10.1016/j.jff.2017.12.051
|
11089
Yamamiya D, Mizukoshi E, Kaji K, Terashima T, Kitahara M, Yamashita T, Arai K, Fushimi K, Honda M, Kaneko S.
Immune responses of human T lymphocytes to novel hepatitis B virus-derived peptides.
PLoS ONE
2018
13(6):e0198264
PubMed ID: 29856876
DOI: 10.1371/journal.pone.0198264
|
11139
Saikawa S, Kaji K, Nishimura N, Seki K, Sato S, Nakanishi K, Kitagawa K, Kawaratani H, Kitade M, Moriya K, Namisaki T, Mitoro A, Yoshiji H.
Angiotensin receptor blockade attenuates cholangiocarcinoma cell growth by inhibiting the oncogenic activity of Yes-associated protein.
Cancer Lett.
2018
434:120-129
PubMed ID: 30031758
DOI: 10.1016/j.canlet.2018.07.021
|
11113
Kawai T, Ota N, Imasato A, Shirasaki Y, Otsuka K, Tanaka Y.
Profiling of N-linked glycans from 100 cells by capillary electrophoresis with large-volume dual preconcentration by isotachophoresis and stacking.
J Chromatogr A
2018
1565:138-144
PubMed ID: 29945790
DOI: 10.1016/j.chroma.2018.06.034
|
11160
Languon S, Tuffour I, Quayson EE, Appiah-Opong R, Quaye O.
In Vitro Evaluation of Cytotoxic Activities of Marketed Herbal Products in Ghana.
J Evid Based Integr Med
2018
PubMed ID: 30088418
DOI: 10.1177/2515690X18790723
|
11292
Hori T, Kurosawa O.
A Three-dimensional Cell Culture Method with a Micromesh Sheet and Its Application to Hepatic Cells.
Tissue Eng Part C Methods
2018
PubMed ID: 30412042
DOI: 10.1089/ten.TEC.2018.0269
|
4452
Phoebe Trio1, Atsuyoshi Kawahara, Satoru Fujisaki, De-Xing Hou
Comparative Gene Expression Profiling in Cultured Cell Lines after Treatment with Wasabi-derived Isothiocyanates
KIMIKA
2018
29, 1-10
DOI: 10.26534/kimika.v29i1.1-10
|
4224
Sultana H, Watanabe K, Rana MM, Takashima R, Ohashi A, Komai M, Shirakawa H.
Effects of Vitamin K₂ on the Expression of Genes Involved in Bile Acid Synthesis and Glucose Homeostasis in Mice with Humanized PXR.
Nutrients
2018
PubMed ID: 30060524
DOI: 10.3390/nu10080982
|
4225
Takashima Y, Horisawa K, Udono M, Ohkawa Y, Suzuki A.
Prolonged inhibition of hepatocellular carcinoma cell proliferation by combinatorial expression of defined transcription factors.
Cancer Sci.
2018
PubMed ID: 30220099
DOI: 10.1111/cas.13798
|
4483
Anusornvongchai T, Nangaku M, Jao TM, Wu CH, Ishimoto Y, Maekawa H, Tanaka T, Shimizu A, Yamamoto M, Suzuki N, Sassa R, Inagi R.
Palmitate deranges erythropoietin production via transcription factor ATF4 activation of unfolded protein response.
Kidney Int.
2018
94(3):536-550
PubMed ID: 29887316
DOI: 10.1016/j.kint.2018.03.011
|
4484
Wang S, Fumoto S, Miyamoto H, Tanaka M, Nishida K.
Edaravone, a cytoprotective drug, enhances transgene expression mediated by lipoplexes in HepG2 cells and mice.
Int J Pharm
2018
548(1):173-181
PubMed ID: 29969708
DOI: 10.1016/j.ijpharm.2018.06.068
|
14907
Takiguchi S, Ayaori M, Yakushiji E, Nishida T, Nakaya K, Sasaki M, Iizuka M, Uto-Kondo H, Terao Y, Yogo M, Komatsu T, Ogura M, Ikewaki K.
Hepatic Overexpression of Endothelial Lipase Lowers High-Density Lipoprotein but Maintains Reverse Cholesterol Transport in Mice: Role of Scavenger Receptor Class B Type I/ATP-Binding Cassette Transporter A1-Dependent Pathways
Arterioscler Thromb Vasc Biol
2018
38(7):1454-1467
PubMed ID: 29748333
DOI: 10.1161/ATVBAHA.118.311056
|
16887
Tanaka T, Hirota T, Ieiri I.
Relationship between DNA Methylation in the 5' CpG Island of the SLC47A1 (Multidrug and Toxin Extrusion Protein MATE1) Gene and Interindividual Variability in MATE1 Expression in the Human Liver
Mol Pharmacol
2018
93(1):1-7
PubMed ID: 29070695
DOI: 10.1124/mol.117.109553
|
9988
Li S, Gao A, Dong S, Chen Y, Sun S, Lei Z, Zhang Z.
Purification, antitumor and immunomodulatory activity of polysaccharides from soybean residue fermented with Morchella esculenta.
Int. J. Biol. Macromol.
2017
96:26-34
PubMed ID: 27939510
DOI: 10.1016/j.ijbiomac.2016.12.007
|
10080
Wakuri S, Yamakage K, Kazuki Y, Kazuki K, Oshimura M, Aburatani S, Yasunaga M, Nakajima Y.
Correlation between luminescence intensity and cytotoxicity in cell-based cytotoxicity assay using luciferase.
Anal. Biochem.
2017
522:18-29
PubMed ID: 28111305
DOI: 10.1016/j.ab.2017.01.015
|
10167
Takahashi K, Suzuki N, Ogra Y.
Bioavailability Comparison of Nine Bioselenocompounds In Vitro and In Vivo.
Int J Mol Sci
2017
18:
PubMed ID: 28245633
DOI: 10.3390/ijms18030506
|
10236
Sudo K, Niikura K, Iwaki K, Kohyama S, Fujiwara K, Doi N.
Human-derived fusogenic peptides for the intracellular delivery of proteins.
J Control Release
2017
255:1-11
PubMed ID: 28385674
DOI: 10.1016/j.jconrel.2017.03.398
|
10351
Nakashima KI, Ogiwara T, Hirai T, Tanaka T, Murata H, Kaburagi K, Fujii-Kuriyama Y, Hayashi H, Inoue M.
Gerontoxanthone B from Maclura cochinchinensis var. gerontogea exhibits anti-inflammatory potential as an aryl hydrocarbon receptor agonist.
Bioorg. Med. Chem.
2017
25:4253-4258
PubMed ID: 28662965
DOI: 10.1016/j.bmc.2017.05.047
|
10392
Ono Y, Tomimori N, Hori H, Kitagawa Y, Shibata H.
Mechanisms of chromosomal aberrations induced by sesamin metabolites in Chinese hamster lung cells.
Mutat. Res.
2017
822:19-26
PubMed ID: 28844238
DOI: 10.1016/j.mrgentox.2017.06.006
|
10435
Tung NH, Uto T, Hai NT, Li G, Shoyama Y.
Quassinoids from the Root of Eurycoma longifolia and Their Antiproliferative Activity on Human Cancer Cell Lines.
Pharmacogn Mag
2017
13:459-462
PubMed ID: 28839372
DOI: 10.4103/pm.pm_353_16
|
10446
Chen Z, Wu Y, Ma YS, Kobayashi Y, Zhao YY, Miura Y, Chiba H, Hui SP.
Profiling of cardiolipins and their hydroperoxides in HepG2 cells by LC/MS.
Anal Bioanal Chem
2017
409:5735-5745
PubMed ID: 28762068
DOI: 10.1007/s00216-017-0515-3
|
10466
Machihara K, Tanaka H, Hayashi Y, Murakami I, Namba T.
Questiomycin A stimulates sorafenib-induced cell death via suppression of glucose-regulated protein 78.
Biochem. Biophys. Res. Commun.
2017
492:33-40
PubMed ID: 28811106
DOI: 10.1016/j.bbrc.2017.08.042
|
10470
Xu Z, Huo J, Ding X, Yang M, Li L, Dai J, Hosoe K, Kubo H, Mori M, Higuchi K, Sawashita J.
Coenzyme Q10 Improves Lipid Metabolism and Ameliorates Obesity by Regulating CaMKII-Mediated PDE4 Inhibition.
Sci Rep
2017
7:8253
PubMed ID: 28811612
DOI: 10.1038/s41598-017-08899-7
|
10478
Fukushima T, Hara-Yamamura H, Nakashima K, Tan LC, Okabe S.
Multiple-endpoints gene alteration-based (MEGA) assay: A toxicogenomics approach for water quality assessment of wastewater effluents.
Chemosphere
2017
188:312-319
PubMed ID: 28888119
DOI: 10.1016/j.chemosphere.2017.08.107
|
10488
Oda Y, Hidaka M, Suzuki A.
Caffeine Has a Synergistic Anticancer Effect with Cisplatin via Inhibiting Fanconi Anemia Group D2 Protein Monoubiquitination in Hepatocellular Carcinoma Cells.
Biol. Pharm. Bull.
2017
40:2005-2009
PubMed ID: 28855448
DOI: 10.1248/bpb.b17-00457
|
10490
Takano M, Kamei H, Nagahiro M, Kawami M, Yumoto R.
Nicotine transport in lung and non-lung epithelial cells.
Life Sci.
2017
188:76-82
PubMed ID: 28866099
DOI: 10.1016/j.lfs.2017.08.030
|
10491
Inoue C, Zhao C, Tsuduki Y, Udono M, Wang L, Nomura M, Katakura Y.
SMARCD1 regulates senescence-associated lipid accumulation in hepatocytes.
NPJ Aging Mech Dis
2017
3:11
PubMed ID: 28868154
DOI: 10.1038/s41514-017-0011-1
|
10494
Toda M, Totoki T, Nakamura C, Yasuma T, D' Alessandro-Gabazza CN, Mifuji-Moroka R, Nishihama K, Iwasa M, Horiki N, Gabazza EC, Takei Y.
Low dose of alcohol attenuates pro-atherosclerotic activity of thrombin.
Atherosclerosis
2017
265:215-224
PubMed ID: 28923781
DOI: 10.1016/j.atherosclerosis.2017.09.005
|
10495
Kawakami K, Moritani C, Uraji M, Fujita A, Kawakami K, Hatanaka T, Suzaki E, Tsuboi S.
Sake lees hydrolysate protects against acetaminophen-induced hepatotoxicity via activation of the Nrf2 antioxidant pathway.
J Clin Biochem Nutr
2017
61:203-209
PubMed ID: 29203962
DOI: 10.3164/jcbn.17-21
|
10531
Oura K, Tadokoro T, Fujihara S, Morishita A, Chiyo T, Samukawa E, Yamana Y, Fujita K, Sakamoto T, Nomura T, Yoneyama H, Kobara H, Mori H, Iwama H, Okano K, Suzuki Y, Masaki T.
Telmisartan inhibits hepatocellular carcinoma cell proliferation in vitro by inducing cell cycle arrest.
Oncol. Rep.
2017
38:2825-2835
PubMed ID: 29048654
DOI: 10.3892/or.2017.5977
|
10552
Okubo S, Uto T, Goto A, Tanaka H, Nishioku T, Yamada K, Shoyama Y.
Berberine Induces Apoptotic Cell Death via Activation of Caspase-3 and -8 in HL-60 Human Leukemia Cells: Nuclear Localization and Structure-Activity Relationships.
Am. J. Chin. Med.
2017
45:1497-1511
PubMed ID: 29025293
DOI: 10.1142/S0192415X17500811
|
10622
Igarashi K, Yamashita K, Katoh H, Kojima K, Ooizumi Y, Nishizawa N, Nishiyama R, Kawamata H, Tajima H, Kaizu T, Kumamoto Y, Watanabe M.
Prognostic significance of promoter DNA hypermethylation of the cysteine dioxygenase 1 (CDO1) gene in primary gallbladder cancer and gallbladder disease.
PLoS ONE
2017
12:e0188178
PubMed ID: 29161283
DOI: 10.1371/journal.pone.0188178
|
10936
Cell Sheet Fabrication Using RGD Peptide-Coupled Alginate Hydrogels Fabricated by an Electrodeposition Method
Chem. Lett.
2017
46, 605–608
DOI: 10.1246/cl.170003
|
10959
Induction of Drug Resistance in Human Hepatoma Cells Cultured on a Silicate Fiber-Based 3D Scaffold
Adv Biochem Biotechnol
2017
112
|
10975
Collagen Microparticle-mediated 3D Cell Organization: A Facile Route to Bottom-Up Engineering of Thick and Porous Tissues
ACS Biomater. Sci. Eng.
2017
3, 2144–2154
PubMed ID: 33440563
DOI: 10.1021/acsbiomaterials.7b00131
|
10990
CYP3A4 induction mechanism of polycyclic aromatic hydrocarbons differs from that of rifampicin in PXR binding element
Fundamental Toxicological Sciences
2017
4, 229-239
DOI: 10.2131/fts.4.229
|
9497
Clyde Gorapava Puilingi, Yuta Kudo, Yuko Cho, Keiichi Konoki, Mari Yotsu-Yamashita
A New Sarasinoside Congener, Sarasinoside M 2, From a Marine Sponge Collected in the Solomon Islands
Biosci Biotechnol Biochem
2017
81(2):222-225
PubMed ID: 27760495
DOI: 10.1080/09168451.2016.1246172
|
10028
Michinori Takashina, Sayaka Inoue, Kei Tomihara, Kengo Tomita, Kohshi Hattori, Qing-Li Zhao, Tokiko Suzuki, Makoto Noguchi, Wakana Ohashi, Yuichi Hattori
Different Effect of Resveratrol to Induction of Apoptosis Depending on the Type of Human Cancer Cells
Int J Oncol
2017
50(3):787-797.
PubMed ID: 28197625
DOI: 10.3892/ijo.2017.3859
|
12319
Yoshihiko Kihara, Riho Maeda, Azusa Imaizumi, Tsukasa Ichikawa, Nobukatsu Nemoto, Tsutomu Ishihara, Nobutaka Hirano, and Mitsuru Haruki
Alkyne-Functionalized Cationic Polysiloxane Polymers Conjugated with Targeting Molecules by Click Reactions for DNA Delivery
Journal of Nanoscience and Nanotechnology
2017
17/7:5081-5089
DOI: 10.1166/jnn.2017.13121
|
14218
Uchiyama T, Ota H, Itaya-Hironaka A, Shobatake R, Yamauchi A, Sakuramoto-Tsuchida S, Makino M, Kimura H, Takeda M, Ohbayashi C, Takasawa S.
Up-regulation of selenoprotein P and HIP/PAP mRNAs in hepatocytes by intermittent hypoxia via down-regulation of miR-203
Biochem Biophys Rep
2017
11:130-137.
PubMed ID: 28955777
DOI: 10.1016/j.bbrep.2017.07.005
|
14233
Trio PZ, Kawahara A, Tanigawa S, Sakao K, Hou DX.
DNA Microarray Profiling Highlights Nrf2-Mediated Chemoprevention Targeted by Wasabi-Derived Isothiocyanates in HepG2 Cells
Nutr Cancer
2017
69(1):105-116
PubMed ID: 27911093
DOI: 10.1080/01635581.2017.1248296
|
14234
Kudou M, Shiozaki A, Kosuga T, Shimizu H, Ichikawa D, Konishi H, Morimura R, Komatsu S, Ikoma H, Fujiwara H, Okamoto K, Marunaka Y, Otsuji E.
Heat shock exerts anticancer effects on liver cancer via autophagic degradation of aquaporin 5
Int J Oncol
2017
50(5):1857-1867
PubMed ID: 28358429
DOI: 10.3892/ijo.2017.3940
|
14435
Sasaki T, Sato Y, Kumagai T, Yoshinari K, Nagata K.
Effect of health foods on cytochrome P450-mediated drug metabolism
J Pharm Health Care Sci
2017
3:14
PubMed ID: 28496987
DOI: 10.1186/s40780-017-0083-x
|
14563
Peng J, Fumoto S, Miyamoto H, Chen Y, Kuroda N, Nishida K.
One-step formation of lipid-polyacrylic acid-calcium carbonate nanoparticles for co-delivery of doxorubicin and curcumin
J Drug Target
2017
25(8):704-714
PubMed ID: 28368667
DOI: 10.1080/1061186X.2017.1315687
|
14725
Minegishi S, Yumura A, Miyoshi H, Negi S, Taketani S, Motterlini R, Foresti R, Kano K, Kitagishi H.
Detection and Removal of Endogenous Carbon Monoxide by Selective and Cell-Permeable Hemoprotein Model Complexes
J Am Chem Soc
2017
139(16):5984-5991
PubMed ID: 28388069
DOI: 10.1021/jacs.7b02229
|
7067
Yamada K, Mito F, Matsuoka Y, Ide S, Shikimachi K, Fujiki A, Kusakabe D, Ishida Y, Enoki M, Tada A, Ariyoshi M, Yamasaki T, Yamato M.
Fluorescence probes to detect lipid-derived radicals.
Nat. Chem. Biol.
2016
12:608-13
PubMed ID: 27294322
DOI: 10.1038/nchembio.2105
|
7092
M Khanmohammadi, S Sakai, T Ashida, M Taya
Production of hyaluronic-acid-based cell-enclosing microparticles and microcapsules via enzymatic reaction using a microfluidic system.
J Applied Polymer Science
2016
133:43107
DOI: 10.1002/app.43107
|
7125
Darwish WS, Ikenaka Y, Nakayama SM, Mizukawa H, Ishizuka M.
Constitutive Effects of Lead on Aryl Hydrocarbon Receptor Gene Battery and Protection by β-carotene and Ascorbic Acid in Human HepG2 Cells.
J. Food Sci.
2016
81:T275-81
PubMed ID: 26630500
DOI: 10.1111/1750-3841.13162
|
7270
Takei T, Kitazono Z, Ozuno Y, Yoshinaga T, Nishimata H, Yoshida M.
Vascular-like network prepared using hollow hydrogel microfibers.
J. Biosci. Bioeng.
2016
121:336-40
PubMed ID: 26199226
DOI: 10.1016/j.jbiosc.2015.06.018
|
7476
Yanagida A, Nakauchi H, Kamiya A.
Generation and In Vitro Expansion of Hepatic Progenitor Cells from Human iPS Cells.
Methods Mol. Biol.
2016
1357:295-310
PubMed ID: 25697415
DOI: 10.1007/7651_2015_199
|
9536
Kumagai T, Aratsu Y, Sugawara R, Sasaki T, Miyairi S, Nagata K.
Indirubin, a component of Ban-Lan-Gen, activates CYP3A4 gene transcription through the human pregnane X receptor.
Drug Metab. Pharmacokinet.
2016
31:139-45
PubMed ID: 26987505
DOI: 10.1016/j.dmpk.2016.01.002
|
9642
Darwish AG, Samy MN, Sugimoto S, Otsuka H, Abdel-Salam H, Matsunami K.
Effects of Hepatoprotective Compounds from the Leaves of Lumnitzera racemosa on Acetaminophen-Induced Liver Damage in Vitro.
Chem. Pharm. Bull.
2016
64:360-5
PubMed ID: 27039833
DOI: 10.1248/cpb.c15-00830
|
9701
Zaitsu Y, Iwatake M, Sato K, Tsukuba T.
Lipid droplets affect elimination of Porphyromonas gingivalis in HepG2 cells by altering the autophagy-lysosome system.
Microbes Infect.
2016
18:565-71
PubMed ID: 27237960
DOI: 10.1016/j.micinf.2016.05.004
|
9717
Miyamae Y, Nishito Y, Nakai N, Nagumo Y, Usui T, Masuda S, Kambe T, Nagao M.
Tetrandrine induces lipid accumulation through blockade of autophagy in a hepatic stellate cell line.
Biochem. Biophys. Res. Commun.
2016
477:40-6
PubMed ID: 27270032
DOI: 10.1016/j.bbrc.2016.06.018
|
9786
Sakai S, Nomura K, Mochizuki K, Taya M.
Anchoring PEG-oleate to cell membranes stimulates reactive oxygen species production.
Colloids Surf B Biointerfaces
2016
147:336-342
PubMed ID: 27544656
DOI: 10.1016/j.colsurfb.2016.08.013
|
9812
Lin Y, Ohkawara B, Ito M, Misawa N, Miyamoto K, Takegami Y, Masuda A, Toyokuni S, Ohno K.
Molecular hydrogen suppresses activated Wnt/β-catenin signaling.
Sci Rep
2016
6:31986
PubMed ID: 27558955
DOI: 10.1038/srep31986
|
9841
Burdeos GC, Ito J, Eitsuka T, Nakagawa K, Kimura F, Miyazawa T.
δ and γ tocotrienols suppress human hepatocellular carcinoma cell proliferation via regulation of Ras-Raf-MEK-ERK pathway-associated upstream signaling.
Food Funct
2016
7:4170-4174
PubMed ID: 27713963
DOI: 10.1039/c6fo00826g
|
9990
Tanaka Y, Tateishi K, Nakatsuka T, Kudo Y, Takahashi R, Miyabayashi K, Yamamoto K, Asaoka Y, Ijichi H, Tateishi R, Shibahara J, Fukayama M, Ishizawa T, Hasegawa K, Kokudo N, Koike K.
Sharpin promotes hepatocellular carcinoma progression via transactivation of Versican expression.
Oncogenesis
2016
5:e277
PubMed ID: 27941932
DOI: 10.1038/oncsis.2016.76
|
10930
Bioactive Compounds from the Leaves of Lumnitzera racemosa against Acetaminophen-induced Liver damage in vitro
Journal of Arid Land Studies
2016
26, 179 - 182
DOI: 10.14976/jals.26.3_183
|
6039
Badr H, Kozai D, Sakaguchi R, Numata T, Mori Y.
Different Contribution of Redox-Sensitive Transient Receptor Potential Channels to Acetaminophen-Induced Death of Human Hepatoma Cell Line.
Front Pharmacol
2016
7:19
PubMed ID: 26903865
DOI: 10.3389/fphar.2016.00019
|
12288
Kung-Kai Kuo, King-Teh Lee, Ker-Kong Chen, Ya-Han Yang, Ying-Chu Lin, Ming-Ho Tsai, Kenly Wuputra, Yen-Liang Lee, Chia-Chen Ku, Hiroyuki Miyoshi, Yukio Nakamura, Shigeo Saito, Chun-Chieh Wu, Chee-Yin Chai, Richard Eckner, Chen-Lung Steve Lin, Sophie S-W Wang, Deng-Chyang Wu, Chang-Shen Lin, Kazunari K Yokoyama
Positive Feedback Loop of OCT4 and c-JUN Expedites Cancer Stemness in Liver Cancer
Stem Cells
2016
34(11):2613-2624
PubMed ID: 27341307
DOI: 10.1002/stem.2447
|
12644
Minatani N, Waraya M, Yamashita K, Kikuchi M, Ushiku H, Kojo K, Ema A, Nishimiya H, Kosaka Y, Katoh H, Sengoku N, Tanino H, Sidransky D, Watanabe M.
Prognostic Significance of Promoter DNA Hypermethylation of cysteine dioxygenase 1 (CDO1) Gene in Primary Breast Cancer
PLoS One
2016
11(1):e0144862
PubMed ID: 26785325
DOI: 10.1371/journal.pone.0144862
|
12854
Kawauchi S, Nakamura T, Horibe S, Tanahashi T, Mizuno S, Hamaguchi T, Rikitake Y.
Down-regulation of hepatic CYP3A1 expression in a rat model of indomethacin-induced small intestinal ulcers
Biopharm Drug Dispos
2016
37(9):522-532
PubMed ID: 27666336
DOI: 10.1002/bdd.2042
|
13986
Liu Y, Sakai S, Taya M.
Engineering tissues with a perfusable vessel-like network using endothelialized alginate hydrogel fiber and spheroid-enclosing microcapsules
Heliyon
2016
2(2):e00067
PubMed ID: 27441246
DOI: 10.1016/j.heliyon.2016.e00067
|
14088
Yoshitaka Koseki, Yoshikazu Ikuta, Takaaki Kamishima, Tsunenobu Onodera, Hidetoshi Oikawa, Hitoshi Kasai
Drug Release is Determined by the Chain Length of Fatty Acid-Conjugated Anticancer Agent as One Component of Nano-Prodrug
Bulletin of the Chemical Society of Japan
2016
89:540–545
DOI: 10.1246/bcsj.20150405
|
14136
Hirata H, Sugimachi K, Komatsu H, Ueda M, Masuda T, Uchi R, Sakimura S, Nambara S, Saito T, Shinden Y, Iguchi T, Eguchi H, Ito S, Terashima K, Sakamoto K, Hirakawa M, Honda H, Mimori K.
Decreased Expression of Fructose-1,6-bisphosphatase Associates with Glucose Metabolism and Tumor Progression in Hepatocellular Carcinoma
Cancer Res
2016
76(11):3265-76
PubMed ID: 27197151
DOI: 10.1158/0008-5472.CAN-15-2601
|
14152
Kazuya Furusawa, Masayuki Tsuchida
Study on the effects of the hierarchical structures of collagen gels on the morphologies of engineered liver cancer tissues
2016 International Symposium on Micro-NanoMechatronics and Human Science (MHS)
2016
DOI: 10.1109/mhs.2016.7824174
|
14165
Kitagishi H, Minegishi S, Yumura A, Negi S, Taketani S, Amagase Y, Mizukawa Y, Urushidani T, Sugiura Y, Kano K.
Feedback Response to Selective Depletion of Endogenous Carbon Monoxide in the Blood
J Am Chem Soc
2016
138(16):5417-25
PubMed ID: 27057920
DOI: 10.1021/jacs.6b02211
|
22046
Okajima W, Komatsu S, Ichikawa D, Miyamae M, Kawaguchi T, Hirajima S, Ohashi T, Imamura T, Kiuchi J, Arita T, Konishi H, Shiozaki A, Moriumura R, Ikoma H, Okamoto K, Taniguchi H, Itoh Y, Otsuji E.
Circulating microRNA profiles in plasma: identification of miR-224 as a novel diagnostic biomarker in hepatocellular carcinoma independent of hepatic function.
Oncotarget
2016
7(33):53820-53836
PubMed ID: 27462777
DOI: 10.18632/oncotarget.10781
|
7128
Sato Y, Sasaki T, Takahashi S, Kumagai T, Nagata K.
Development of a highly reproducible system to evaluate inhibition of cytochrome P450 3A4 activity by natural medicines.
J Pharm Pharm Sci
2015
18:316-27
PubMed ID: 26626238
DOI: 10.18433/j3vk5g
|
7219
Yamaza T, Alatas FS, Yuniartha R, Yamaza H, Fujiyoshi JK, Yanagi Y, Yoshimaru K, Hayashida M, Matsuura T, Aijima R, Ihara K, Ohga S, Shi S, Nonaka K, Taguchi T.
In vivo hepatogenic capacity and therapeutic potential of stem cells from human exfoliated deciduous teeth in liver fibrosis in mice.
Stem Cell Res Ther
2015
6:171
PubMed ID: 26358689
DOI: 10.1186/s13287-015-0154-6
|
7238
Ozeki M, Salah A, Aini W, Tamaki K, Haga H, Miyagawa-Hayashino A.
Abnormal Localization of STK17A in Bile Canaliculi in Liver Allografts: An Early Sign of Chronic Rejection.
PLoS ONE
2015
10:e0136381
PubMed ID: 26305096
DOI: 10.1371/journal.pone.0136381
|
7257
Anan Y, Kimura M, Hayashi M, Koike R, Ogra Y.
Detoxification of selenite to form selenocyanate in mammalian cells.
Chem. Res. Toxicol.
2015
28:1803-14
PubMed ID: 26243445
DOI: 10.1021/acs.chemrestox.5b00254
|
7278
Yamaori S, Kinugasa Y, Jiang R, Takeda S, Yamamoto I, Watanabe K.
Cannabidiol induces expression of human cytochrome P450 1A1 that is possibly mediated through aryl hydrocarbon receptor signaling in HepG2 cells.
Life Sci.
2015
136:87-93
PubMed ID: 26187180
DOI: 10.1016/j.lfs.2015.07.007
|
7324
Somiya M, Yamaguchi K, Liu Q, Niimi T, Maturana AD, Iijima M, Yoshimoto N, Kuroda S.
One-step scalable preparation method for non-cationic liposomes with high siRNA content.
Int J Pharm
2015
490:316-23
PubMed ID: 26027493
DOI: 10.1016/j.ijpharm.2015.05.072
|
7474
Suzuki Y, Nakagawa K, Kato S, Tatewaki N, Mizuochi S, Ito J, Eitsuka T, Nishida H, Miyazawa T.
Metabolism and cytotoxic effects of phosphatidylcholine hydroperoxide in human hepatoma HepG2 cells.
Biochem. Biophys. Res. Commun.
2015
458:920-7
PubMed ID: 25704087
DOI: 10.1016/j.bbrc.2015.02.063
|
7553
Priscilla Boccia, Claudia Meconi, Elena Sturchio, Salvatore Margiotta, Pietro Ragone, Vito Summa
Natural geochemical risk in the Pollino Massif: a case-study of chromium.
Frontiers in Genetics
2015
6:
DOI: 10.3389/conf.fgene.2015.01.00023
|
7568
Tung NH, Uto T, Morinaga O, Shoyama Y
Chemical Constituents from the Aerial Parts of Bupleurum falcatum L. and Biological Evidences.
Natural Product Sciences
2015
21:71-75
|
10187
Wageh Sobhy Darwish, Yoshinori Ikenaka, Shouta Nakayama, Hazuki Mizukawa, Mayumi Ishizuka
Mutagenicity of Modelled-Heat-Treated Meat Extracts: Mutagenicity Assay, Analysis and Mechanism of Mutagenesis
Jpn J Vet Res
2015
63(4):173-82
PubMed ID: 26753243
|
14962
Kazuya Furusawa, Masayuki Tsuchida, Saki Yahata
Construction of engineered liver cancer tissues with multichannel collagen gel
2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS)
2015
2015-11
DOI: 10.1109/MHS.2015.7438238
|
15144
Kawase A, Hata S, Takagi M, Iwaki M.
Pravastatin Modulate Niemann-Pick C1-Like 1 and ATP-Binding Cassette G5 and G8 to Influence Intestinal Cholesterol Absorption
J Pharm Pharm Sci
2015
18(5):765-7
PubMed ID: 26670369
DOI: 10.18433/j3m029
|
15145
Mira A, Shimizu K.
In vitro Cytotoxic Activities and Molecular Mechanisms of Angelica shikokiana Extract and its Isolated Compounds
Pharmacogn Mag
2015
11(Suppl 4):S564-9
PubMed ID: 27013795
DOI: 10.4103/0973-1296.172962
|
15159
Honda S, Loher P, Shigematsu M, Palazzo JP, Suzuki R, Imoto I, Rigoutsos I, Kirino Y.
Sex hormone-dependent tRNA halves enhance cell proliferation in breast and prostate cancers
Proc Natl Acad Sci U S A
2015
112(29):E3816-25
PubMed ID: 26124144
DOI: 10.1073/pnas.1510077112
|
15195
Ohtera A, Miyamae Y, Yoshida K, Maejima K, Akita T, Kakizuka A, Irie K, Masuda S, Kambe T, Nagao M.
Identification of a New Type of Covalent PPARγ Agonist using a Ligand-Linking Strategy
ACS Chem Biol
2015
10(12):2794-804
PubMed ID: 26414848
DOI: 10.1021/acschembio.5b00628
|
17094
Kondo Y, Yoshihashi S, Mimori K, Ogihara R, Kanehama Y, Maki Y, Enosawa S, Kurose K, Iwao T, Nakamura K, Matsunaga T.
Selective culture method for hepatocyte-like cells differentiated from human induced pluripotent stem cells
Drug Metab Pharmacokinet
2014
29(5):407-13
PubMed ID: 24785642
DOI: 10.2133/dmpk.dmpk-14-rg-022
|
17121
Tokumoto M, Kutsukake N, Yamanishi E, Katsuta D, Anan Y, Ogra Y.
Arsenic (+3 oxidation state) methyltransferase is a specific but replaceable factor against arsenic toxicity
Toxicol Rep
2014
1:589-595
PubMed ID: 28962272
DOI: 10.1016/j.toxrep.2014.08.011
|
17125
Tsuji S, Kawamura F, Kubiura M, Hayashi A, Ohbayashi T, Kazuki Y, Chesné C, Oshimura M, Tada M.
Dual-color fluorescence imaging to monitor CYP3A4 and CYP3A7 expression in human hepatic carcinoma HepG2 and HepaRG cells
PLoS One
2014
9(8):e104123
PubMed ID: 25101946
DOI: 10.1371/journal.pone.0104123
|
17130
Kondo Y, Iwao T, Nakamura K, Sasaki T, Takahashi S, Kamada N, Matsubara T, Gonzalez FJ, Akutsu H, Miyagawa Y, Okita H, Kiyokawa N, Toyoda M, Umezawa A, Nagata K, Matsunaga T, Ohmori S.
An efficient method for differentiation of human induced pluripotent stem cells into hepatocyte-like cells retaining drug metabolizing activity
Drug Metab Pharmacokinet
2014
29(3):237-43
PubMed ID: 24334537
DOI: 10.2133/dmpk.dmpk-13-rg-104
|
15776
Hara-Yamamura H, Nakashima K, Hoque A, Miyoshi T, Kimura K, Watanabe Y, Okabe S.
Evaluation of whole wastewater effluent impacts on HepG2 using DNA microarray-based transcriptome analysis
Environ Sci Technol
2013
47(10):5425-32
PubMed ID: 23590814
DOI: 10.1021/es4002955
|
16090
Uemura T, Tanaka Y, Higashi K, Miyamori D, Takasaka T, Nagano T, Toida T, Yoshimoto K, Igarashi K, Ikegaya H.
Acetaldehyde-induced cytotoxicity involves induction of spermine oxidase at the transcriptional level
Toxicology
2013
310:1-7
PubMed ID: 23707493
DOI: 10.1016/j.tox.2013.05.008
|
21984
Yanagida A, Ito K, Chikada H, Nakauchi H, Kamiya A.
An in vitro expansion system for generation of human iPS cell-derived hepatic progenitor-like cells exhibiting a bipotent differentiation potential.
PLoS One
2013
8(7):e67541
PubMed ID: 23935837
DOI: 10.1371/journal.pone.0067541
|
21985
Okudaira N, Okamura T, Tamura M, Iijma K, Goto M, Matsunaga A, Ochiai M, Nakagama H, Kano S, Fujii-Kuriyama Y, Ishizaka Y.
Long interspersed element-1 is differentially regulated by food-borne carcinogens via the aryl hydrocarbon receptor.
Oncogene
2013
32(41):4903-12
PubMed ID: 23208499
DOI: 10.1038/onc.2012.516
|
22072
Tanigawa S, Lee CH, Lin CS, Ku CC, Hasegawa H, Qin S, Kawahara A, Korenori Y, Miyamori K, Noguchi M, Lee LH, Lin YC, Steve Lin CL, Nakamura Y, Jin C, Yamaguchi N, Eckner R, Hou DX, Yokoyama KK.
Jun dimerization protein 2 is a critical component of the Nrf2/MafK complex regulating the response to ROS homeostasis.
Cell Death Dis
2013
4(11):e921
PubMed ID: 24232097
DOI: 10.1038/cddis.2013.448
|
18989
Ohno M, Ikenaka Y, Ishizuka M.
Sudan III dye strongly induces CYP1A1 mRNA expression in HepG2 cells
J Biochem Mol Toxicol
2012
26(1):16-22
PubMed ID: 22287322
DOI: 10.1002/jbt.20408
|
12539
Kawano Y, Nagata M, Kohno T, Ichimiya A, Iwakiri T, Okumura M, Arimori K.
Caffeine increases the antitumor effect of Cisplatin in human hepatocellular carcinoma cells
Biol Pharm Bull
2012
35(3):400-7
PubMed ID: 22382328
DOI: 10.1248/bpb.35.400
|
12730
Ohno M, Ikenaka Y, Ishizuka M.
All-trans retinoic acid inhibits the recruitment of ARNT to DNA, resulting in the decrease of CYP1A1 mRNA expression in HepG2 cells
Biochem Biophys Res Commun
2012
417(1):484-9
PubMed ID: 22177959
DOI: 10.1016/j.bbrc.2011.11.146
|
21982
Ogawa A, Okuda N, Hio K, Kanematsu H, Tamauchi H.
The monitoring possibility of some mammalian cells for zinc concentrations on metallic materials.
Cytotechnology
2012
64(3):341-7
PubMed ID: 22331507
DOI: 10.1007/s10616-012-9433-6
|
12473
Sone Y, Ueta E, Sannomaru Y, Miyake N, Sone H, Otsuka Y, Kondo K, Kurata T, Suzuki E.
Dose of 3-methylcholanthrene enhances vitamin C accumulation and mRNA expression of its transporter in the liver of ODS rats and in HepG2 cells
J Biochem Mol Toxicol
2011
25(6):369-76
PubMed ID: 21800402
DOI: 10.1002/jbt.20403
|
18708
Takiguchi M, Darwish WS, Ikenaka Y, Ohno M, Ishizuka M.
Metabolic activation of heterocyclic amines and expression of CYP1A1 in the tongue
Toxicol Sci
2010
116(1):79-91
PubMed ID: 20308224
DOI: 10.1093/toxsci/kfq087
|
9996
Arnal JF, Battle T, Rasetti C, Challah M, Costerousse O, Vicaut E, Michel JB, Alhenc-Gelas F.
ACE in three tunicae of rat aorta: expression in smooth muscle and effect of renovascular hypertension.
Am. J. Physiol.
1994
267:H1777-84
PubMed ID: 7977808
DOI: 10.1152/ajpheart.1994.267.5.H1777
|