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Cell No. : Cell Name
RCB1871 : TL-1  update : 2020/09/24
CommentHuman lymphoid cell line derived from Burkitt's lymphoma. Tumorigenic in nude mouse. TKG0607 (Deposited from Tohoku Univ.). Application consideration
Comment from the depositor
Terms and conditionsThere is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, a prior written permission of the DEPOSITOR or the RIKEN BRC is necessary.
Order Form Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, Category I and II, depending on the sort of user institutions and the purposes of use.Please use an appropriate MTA(to see).In case of Restriction "a" or "f", please contact RIKEN BRC( regarding any kind of for-profit use.
Basic information Depositor Obinata, Masuo
Originator Hayashi, Yutaka (Tohoku University)
Year of deposit 2004
Original cell TKG0607
Animal human < Mammals
Genus Homo
Species sapiens
Tissue ileocecal lymph node meta
Classification cancer
History Cell Resource Center for Biomedical Research, Tohoku University(TKG0607)
Lifespan infinite
Morphology other
deposit info
lot info
Medium Medium List
Culture type Suspension cells
Medium and additives RPMI1640 + 10% FBS
Antibiotics Free
Passage method dilution
Culture information Passage ratio 1 : 4 split
SC frequency Subculture : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
STR(human) OK
Virus (HIV) LT 400
Virus (HTLV-1) (-)
Isozyme LD, NP
Chromosome mode 47-49(50) : 47(11),48(38),49(1)
Reference information Reference 2
User's Publication 2

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5005  Yaoita S1, Ohoi R, Hayashi Y, Watanabe T.  Establishment and characterization of TL-1 cell line from a ileo-cecal Burkitt's lymphoma  Hum Cell  1989  2(2):197  PubMed ID: 2486610
2710  Hayashi Y, Matsumura Y, Nishihira T, Watanabe I, Ohi R, Kasai M, Kumagai K, Kamada N  Burkitt's lymphoma cell line bearing surface IgA and negative for nuclear antigen of Epstein-Barr virus (EBNA).  Jpn J Exp Med  1980  50:423-34  PubMed ID: 6268866

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User's Publication
11858  Shinojima N, Fujimoto K, Makino K, Todaka K, Yamada K, Mikami Y, Oda K, Nakamura K, Jono H, Kuratsu JI, Nakamura H, Yano S, Mukasa A.  Clinical significance of polyglutamylation in primary central nervous system lymphoma.  Acta Neuropathol Commun  2018    PubMed ID: 29475458
10269  Komohara Y, Ma C, Yano H, Pan C, Horlad H, Saito Y, Ohnishi K, Fujiwara Y, Okuno Y, Nosaka K, Shimosaki S, Morishita K, Matsuoka M, Wakayama T, Takeya M.  Cell adhesion molecule-1 (CADM1) expressed on adult T-cell leukemia/lymphoma cells is not involved in the interaction with macrophages.  J Clin Exp Hematop  2017  57:15-20  PubMed ID: 28420814

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