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19831
Yamaguchi F, Sakane H, Akasaki K.
Comparative study of the steady-state subcellular distribution of lysosome-associated membrane glycoprotein-2 (LAMP-2) isoforms with GYXXΦ-type tyrosine-based motifs that interact differently with four adaptor protein (AP) complexes
J Biochem
2024
175(3):275-287
PubMed ID: 37983719
DOI: 10.1093/jb/mvad096
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19873
Kataoka H, Akiyoshi T, Uchida Y, Imaoka A, Terasaki T, Ohtani H.
The effects of N-glycosylation on the expression and transport activity of OATP1A2 and OATP2B1
J Pharm Sci
2024
S0022-3549(24)00058-3
PubMed ID: 38432624
DOI: 10.1016/j.xphs.2024.02.012
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Mixich L, Boonstra E, Masuda K, Li SW, Nakashima Y, Meng F, Sakata M, Goda T, Uchida S, Cabral H.
Ionizable Polymeric Micelles with Phenylalanine Moieties Enhance Intracellular Delivery of Self-Replicating RNA for Long-Lasting Protein Expression In Vivo
Biomacromolecules
2024
Jan 5
PubMed ID: 38181450
DOI: 10.1021/acs.biomac.3c01102
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21560
Wang A, Uchida K, Yokoyama A, Higashino F, Yasuda M.
Human adenovirus oncolytic properties and the inhibitory role of E4 orf4 and E4 orf6/7 on endogenously activated NF-κB.
Biochem Biophys Rep
2024
37:101616
PubMed ID: 38205184
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21700
Katayama K, Ito J, Murakami R, Yamashita A, Sasajima H, Narahashi S, Chiba J, Yamamoto I, Fujii W, Tochigi Y, Suzuki H.
Mutation of the Thap4 gene causes dwarfism and testicular anomalies in rats and mice.
Mamm Genome
2024
PubMed ID: 38658415
DOI: 10.1007/s00335-024-10041-8
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21741
Kato S, Tamura K, Masuda Y, Konishi M, Yamanaka K, Oikawa T.
A novel type IIb L-asparaginase from Latilactobacillus sakei LK-145: characterization and application.
Arch Microbiol
2024
206(6):266
PubMed ID: 38761213
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21778
Imamura I, Kiyama R.
Potential involvement of KANK1 haploinsufficiency in centrosome aberrations.
Biochim Biophys Acta Gen Subj
2024
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PubMed ID: 38830559
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21794
Zhou J, Murata H, Tomonobu N, Mizuta N, Yamakawa A, Yamamoto KI, Kinoshita R, Sakaguchi M.
S100A11 is involved in the progression of colorectal cancer through the desmosome-catenin-TCF signaling pathway.
In Vitro Cell Dev Biol Anim
2024
PubMed ID: 38842658
DOI: 10.1007/s11626-024-00930-2
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21796
Hara Y, Ichiraku A, Matsuda T, Sakane A, Sasaki T, Nagai T, Horikawa K.
High-affinity tuning of single fluorescent protein-type indicators by flexible linker length optimization in topology mutant.
Commun Biol
2024
PubMed ID: 38851844
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21798
Ichiyama-Kobayashi S, Hata K, Wakamori K, Takahata Y, Murakami T, Yamanaka H, Takano H, Yao R, Uzawa N, Nishimura R.
Chromatin profiling identifies chondrocyte-specific Sox9 enhancers important for skeletal development.
JCI Insight
2024
9(11)
PubMed ID: 38855864
DOI: 10.1172/jci.insight.175486
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21799
Yamamoto R, Segawa R, Kato H, Niino Y, Sato T, Hiratsuka M, Hirasawa N.
Identification of amino acids in transmembrane domains of mutated cytokine receptor-like factor 2 and interleukin-7 receptor α required for constitutive signal transduction.
Biochim Biophys Acta Biomembr
2024
184359
PubMed ID: 38862034
DOI: 10.1016/j.bbamem.2024.184359
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21837
Maruyama Y, Ohsawa Y, Suzuki T, Yamauchi Y, Ohno K, Inoue H, Yamamoto A, Hayashi M, Okuhara Y, Muramatsu W, Namiki K, Hagiwara N, Miyauchi M, Miyao T, Ishikawa T, Horie K, Hayama M, Akiyama N, Hirokawa T, Akiyama T.
Pseudoirreversible inhibition elicits persistent efficacy of a sphingosine 1-phosphate receptor 1 antagonist.
Nat Commun
2024
15(1):5743
PubMed ID: 39030171
DOI: 10.1038/s41467-024-49893-8
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21962
Okamoto Y, Kitakaze K, Takenouchi Y, Matsui R, Koga D, Miyashima R, Ishimaru H, Tsuboi K.
GPR176 promotes fibroblast-to-myofibroblast transition in organ fibrosis progression.
Biochim Biophys Acta Mol Cell Res
2024
1871(7):119798
PubMed ID: 39047914
DOI: 10.1016/j.bbamcr.2024.119798
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22008
Kawaue H, Matsubara T, Nagano K, Ikedo A, Rojasawasthien T, Yoshimura A, Nakatomi C, Imai Y, Kakuta Y, Addison WN, Kokabu S.
KIF22 regulates mitosis and proliferation of chondrocyte cells.
iScience
2024
27(7):110151
PubMed ID: 38989461
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22009
Ishizawa M, Takano M, Kittaka A, Matsumoto T, Makishima M.
2α-Substituted Vitamin D Derivatives Effectively Enhance the Osteoblast Differentiation of Dedifferentiated Fat Cells.
Biomolecules
2024
14(6)
PubMed ID: 38927109
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22068
Kato S, Deguchi K, Obana M, Fujio Y, Fukuda Y, Inoue T.
Metabolite phosphatase from anhydrobiotic tardigrades.
FEBS J
2024
PubMed ID: 39417615
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Oyama S, Zhang H, Ferdous R, Tomochika Y, Chen B, Jiang S, Islam MS, Hasan MM, Zhai Q, Waliullah ASM, Ping Y, Yan J, Mimi MA, Zhang C, Aramaki S, Takanashi Y, Kahyo T, Hashizume Y, Kaneda D, Setou M.
UBL3 Interacts with PolyQ-Expanded Huntingtin Fragments and Modifies Their Intracellular Sorting.
Neurol Int
2024
16(6):1175-1188
PubMed ID: 39449505
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22131
Kawataki S, Kubota Y, Katayama K, Imoto S, Takekawa M.
GADD45β-MTK1 signaling axis mediates oncogenic stress-induced activation of the p38 and JNK pathways.
Cancer Sci
2024
PubMed ID: 39526327
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22236
Lin N, Miyamoto K, Ogawara T, Sakurai S, Kizaka-Kondoh S, Kadonosono T.
Epitope binning for multiple antibodies simultaneously using mammalian cell display and DNA sequencing
Commun Biol
2024
7(1):652
PubMed ID: 38806676
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22237
Mubuchi A, Takechi M, Nishio S, Matsuda T, Itoh Y, Sato C, Kitajima K, Kitagawa H, Miyata S.
Assembly of neuron- and radial glial-cell-derived extracellular matrix molecules promotes radial migration of developing cortical neurons
Elife
2024
12:RP92342
PubMed ID: 38512724
DOI: 10.7554/eLife.92342
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Arasawa T, Hiwasa T, Kagaya A, Maruyama T, Uesato M, Kano M, Kobayashi S, Takizawa H, Iwase K, Nomura F, Matsushita K, Matsubara H.
Analysis of patients with colorectal cancer shows a specific increase in serum anti-ING1 autoantibody levels
BMC Cancer
2023
23(1):356
PubMed ID: 37072777
DOI: 10.1186/s12885-023-10845-y
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17778
Shinya Usui, Qiunan Zhu, Hisakazu Komori, Yui Iwamoto, Takumi Nishiuchi, Yoshiyuki Shirasaka, Ikumi Tamai
Apple-derived extracellular vesicles modulate the expression of human intestinal bile acid transporter ASBT/SLC10A2 via downregulation of transcription factor RARα
Drug Metabolism and Pharmacokinetics
2023
DOI: 10.1016/j.dmpk.2023.100512
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Yan J, Zhang H, Tomochika Y, Chen B, Ping Y, Islam MS, Aramaki S, Sato T, Nagashima Y, Nakamura T, Kahyo T, Kaneda D, Ogawa K, Yoshida M, Setou M.
UBL3 Interaction with α-Synuclein Is Downregulated by Silencing MGST3
Biomedicines
2023
11(9):2491
PubMed ID: 37760932
DOI: 10.3390/biomedicines11092491
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19666
Aso A, Nabetani H, Matsuura Y, Kadonaga Y, Shirakami Y, Watabe T, Yoshiya T, Mochizuki M, Ooe K, Kawakami A, Jinno N, Toyoshima A, Haba H, Wang Y, Cardinale J, Giesel FL, Shimoyama A, Kaneda-Nakashima K, Fukase K.
Evaluation of Astatine-211-Labeled Fibroblast Activation Protein Inhibitor (FAPI): Comparison of Different Linkers with Polyethylene Glycol and Piperazine
Int J Mol Sci
2023
24(10):8701
PubMed ID: 37240044
DOI: 10.3390/ijms24108701
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Takeuchi M, Nishisho T, Toki S, Kawaguchi S, Tamaki S, Oya T, Uto Y, Katagiri T, Sairyo K.
Blue light induces apoptosis and autophagy by promoting ROS-mediated mitochondr
Cancer Med
2023
12(8):9668-9683
PubMed ID: 36722116
DOI: 10.1002/cam4.5664
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19701
Yamamoto R, Segawa R, Liu J, Isaji T, Gu J, Hiratsuka M, Hirasawa N.
Effect of N-glycosylation on constitutive signal transduction by mutated cytokine receptor-like factor 2
Biochim Biophys Acta Gen Subj
2023
1867(11):130465
PubMed ID: 37748663
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19785
Yamamoto H, Tanaka Y, Sawada M, Kihara S.
ERRα Attenuates Vascular Inflammation via Enhanced NFκB Degradation Pathway
Endocrinology
2023
164(3):bqac212
PubMed ID: 36534970
DOI: 10.1210/endocr/bqac212
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19803
Murase W, Kubota A, Ikeda-Araki A, Terasaki M, Nakagawa K, Shizu R, Yoshinari K, Kojima H.
Effects of perfluorooctanoic acid (PFOA) on gene expression profiles via nuclear receptors in HepaRG cells: Comparative study with in vitro transactivation assays
Toxicology
2023
494:153577
PubMed ID: 37302725
DOI: 10.1016/j.tox.2023.153577
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19809
Tezuka M, Yonekubo-Awaka S, Tamai Y, Tsuchioka K, Kobayashi K, Kuramochi Y, Tatemichi S, Nagasawa T, Kiguchi S.
Suppression of hypothalamic-pituitary-gonadal function by linzagolix in benign prostatic hyperplasia and polycystic ovary syndrome animal models
Clin Exp Pharmacol Physiol
2023
50(11):914-923
PubMed ID: 37622483
DOI: 10.1111/1440-1681.13817
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19876
Maekawa K, Ishizawa M, Ikawa T, Sajiki H, Matsumoto T, Tokiwa H, Makishima M, Yamada S.
Syntheses of 25-Adamantyl-25-alkyl-2-methylidene-1α,25-dihydroxyvitamin D3 Derivatives with Structure-Function Studies of Antagonistic and Agonistic Active Vitamin D Analogs
Biomolecules
2023
13(7):1082
PubMed ID: 37509118
DOI: 10.3390/biom13071082
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19899
Nakamura T, Sugeno N, Hasegawa T, Ikeda K, Yoshida S, Ishiyama S, Sato K, Takeda A, Aoki M.
Alpha-synuclein promotes PRMT5-mediated H4R3me2s histone methylation by interacting with the BAF complex
FEBS J
2023
Dec 17
PubMed ID: 38105619
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19947
Moriizumi H, Kubota Y, Tsuchiya T, Naka R, Takekawa M.
Caspase 3-specific cleavage of MEK1 suppresses ERK signaling and sensitizes cells to stress-induced apoptosis
FEBS Open Bio
2023
13(4):684-700
PubMed ID: 36776127
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19987
Miyajima Y, Noguchi-Yachide T, Ochiai K, Fujii S.
Physicochemical characterization of B-hydroxyphenyl phosphine borane derivatives and their evaluation as nuclear estrogen receptor ligands
RSC Med Chem
2023
15(1):119-12
PubMed ID: 38283218
DOI: 10.1039/d3md00350g
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21018
Nakashima KI, Okamura M, Matsumoto I, Kameda N, Tsuboi T, Yamaguchi E, Itoh A, Inoue M.
Regulation of adipogenesis through retinoid X receptor and/or peroxisome proliferator-activated receptor by designed lignans based on natural products in 3T3-L1 cells.
J Nat Med
2023
PubMed ID: 36607539
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21023
Nakamura Y, Aizawa C, Kawata H, Nakanishi T.
N-glycosylation Modifies Prostaglandin E2 Uptake by Reducing Cell Surface Expression of SLCO2A1.
Prostaglandins Other Lipid Mediat
2023
106714
PubMed ID: 36706979
DOI: 10.1016/j.prostaglandins.2023.106714
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21041
Shiraki A, Shimizu S.
The molecular associations in clathrin-coated pit regulate β-arrestin-mediated MAPK signaling downstream of μ-opioid receptor.
Biochem Biophys Res Commun
2023
640:64-72
PubMed ID: 36502633
DOI: 10.1016/j.bbrc.2022.11.098
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21068
Yamakado N, Okuda S, Tobiume K, Uetsuki R, Ono S, Mizuta K, Nakagawa T, Aikawa T.
Chemical inhibition of LSD1 leads to epithelial to mesenchymal transition in vitro of an oral squamous cell carcinoma OM-1 cell line via release from LSD1-dependent suppression of ZEB1.
Biochem Biophys Res Commun
2023
647:23-29
PubMed ID: 36709669
DOI: 10.1016/j.bbrc.2023.01.062
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21100
Suzuki Y, Nakamoto C, Watanabe-Iida I, Watanabe M, Takeuchi T, Sasaoka T, Abe M, Sakimura K.
Quantitative analysis of NMDA receptor subunits proteins in mouse brain.
Neurochem Int
2023
105517
PubMed ID: 36913980
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21116
Komuro R, Honda Y, Yanaizu M, Nagahama M, Kino Y.
Alzheimer's Disease-Associated Alternative Splicing of CD33 Is Regulated by the HNRNPA Family Proteins.
Cells
2023
12(4)
PubMed ID: 36831269
DOI: 10.3390/cells12040602
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21153
Yang W, Miyazaki T, Nakagawa Y, Boonstra E, Masuda K, Nakashima Y, Chen P, Mixich L, Barthelmes K, Matsumoto A, Mi P, Uchida S, Cabral H.
Block catiomers with flanking hydrolyzable tyrosinate groups enhance in vivo mRNA delivery via π-π stacking-assisted micellar assembly.
Sci Technol Adv Mater
2023
24(1):2170164
PubMed ID: 36950277
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21214
Ohba K, Sehara Y, Enoki T, Mineno J, Ozawa K, Mizukami H.
Adeno-associated virus vector system controlling capsid expression improves viral quantity and quality.
iScience
2023
26(4):106487
PubMed ID: 37096037
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21246
Ishiyama S, Hasegawa T, Sugeno N, Kobayashi J, Yoshida S, Miki Y, Wakabayashi K, Fukuda M, Kawata Y, Nakamura T, Sato K, Ezura M, Kikuchi A, Takeda A, Aoki M.
Sortilin acts as an endocytic receptor for α-synuclein fibril.
FASEB J
2023
37(7):e23017
PubMed ID: 37272890
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21270
Yamaguchi S, Kamino M, Hamamura M, Otsuguro KI.
The cytosolic N-terminal region of heterologously-expressed transmembrane channel-like protein 1 (TMC1) can be cleaved in HEK293 cells.
PLoS One
2023
18(6):e0287249
PubMed ID: 37352201
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21333
Kogaki T, Hase H, Tanimoto M, Tashiro A, Kitae K, Ueda Y, Jingushi K, Tsujikawa K.
ALKBH4 is a novel enzyme that promotes translation through modified uridine regulation.
J Biol Chem
2023
105093
PubMed ID: 37507018
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21384
Nishida K, Wang G, Kobatake E, Mie M.
Sensitive Detection of Tumor Cells Using Protein Nanoparticles with Multiple Displays of DNA Aptamers and Bioluminescent Reporters.
ACS Biomater Sci Eng
2023
PubMed ID: 37642536
DOI: 10.1021/acsbiomaterials.3c00712
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21453
Yajima K, Akiyoshi T, Sakamoto K, Suzuki Y, Oka T, Imaoka A, Yamamura H, Kurokawa J, Ohtani H.
Determination of single-molecule transport activity of OATP2B1 by measuring the number of transporter molecules using electrophysiological approach.
J Pharmacol Sci
2023
153(3):153-160
PubMed ID: 37770156
DOI: 10.1016/j.jphs.2023.08.008
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21467
Suzuki S, Saito S, Narushima Y, Kodani S, Kagaya N, Suenaga H, Shin-Ya K, Arai MA.
Notch activator cyclopiazonic acid induces apoptosis in HL-60 cells through calcineurin activation.
J Antibiot (Tokyo)
2023
PubMed ID: 37938761
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21485
Zhao X, Ma D, Ishiguro K, Saito H, Akichika S, Matsuzawa I, Mito M, Irie T, Ishibashi K, Wakabayashi K, Sakaguchi Y, Yokoyama T, Mishima Y, Shirouzu M, Iwasaki S, Suzuki T, Suzuki T.
Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell
2023
PubMed ID: 37992713
DOI: 10.1016/j.cell.2023.10.026
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21508
Kenji Ohba, Hiroaki Mizukami
Protocol for producing an adeno-associated virus vector by controlling capsid expression timing
STAR Protocols
2023
4:102542
PubMed ID: 38103199
DOI: 10.1016/j.xpro.2023.102542
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21534
Ohkawa Y, Kanto N, Nakano M, Fujinawa R, Kizuka Y, Johnson EL, Harada Y, Tamura JI, Taniguchi N.
Involvement of langerin in the protective function of a keratan sulfate-based disaccharide in an emphysema mouse model.
J Biol Chem
2023
299(8):105052
PubMed ID: 37454739
DOI: 10.1016/j.jbc.2023.105052
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17537
Emiko Kinoshita-Kikuta, Yoko Ino, Yayoi Kimura, Tomoko Akiyama, Eiji Kinoshita, Tohru Koike
Use of Escherichia coli expression system for analyzing kinase motifs
Journal of Electrophoresis
2022
66:13-20
DOI: 10.2198/jelectroph.66.13
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17583
Han H, Akiyoshi T, Morita T, Kataoka H, Katayama K, Yajima K, Imaoka A, Ohtani H.
Comparison of the transport kinetics of fexofenadine and its pH dependency among OATP1A2 genetic variants
Drug Metab Pharmacokinet
2022
47:100470
PubMed ID: 36116173
DOI: 10.1016/j.dmpk.2022.100470
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17609
Yoshihara A, Kawasaki H, Masuno H, Takada K, Numoto N, Ito N, Hirata N, Kanda Y, Ishizawa M, Makishima M, Kagechika H, Tanatani A.
Lithocholic Acid Amides as Potent Vitamin D Receptor Agonists
Biomolecules
2022
12(1):130
PubMed ID: 35053278
DOI: 10.3390/biom12010130
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17708
Nakamura Y, Kozakai H, Nishio T, Yoshida K, Nakanishi T.
Phenolsulfonphthalein as a surrogate substrate to assess altered function of the prostaglandin transporter SLCO2A1
Drug Metab Pharmacokinet
2022
44:100452
PubMed ID: 35299026
DOI: 10.1016/j.dmpk.2022.100452
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17798
Chen P, Yang W, Hong T, Miyazaki T, Dirisala A, Kataoka K, Cabral H.
Nanocarriers escaping from hyperacidified endo/lysosomes in cancer cells allow tumor-targeted intracellular delivery of antibodies to therapeutically inhibit c-MYC
Biomaterials
2022
288:121748
PubMed ID: 36038419
DOI: 10.1016/j.biomaterials.2022.121748
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Shams R, Matsukawa A, Ochi Y, Ito Y, Miyatake H.
In Silico and In Cell Hybrid Selection of Nonrapalog Ligands to Allosterically Inhibit the Kinase Activity of mTORC1
J Med Chem
2022
Jun 30
PubMed ID: 34191518
DOI: 10.1021/acs.jmedchem.1c00536
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Urabe T, Miyoshi H, Narasaki S, Yanase Y, Uchida K, Noguchi S, Hide M, Tsutsumi YM, Sakai N.
Characterization of intracellular calcium mobilization induced by remimazolam, a newly approved intravenous anesthetic.
PLoS One
2022
17(2):e0263395
PubMed ID: 35104283
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Sakamoto T, Yu Z, Otani Y.
Dual-Color Fluorescence Switch-On Probe for Imaging G-Quadruplex and Double-Stranded DNA in Living Cells
Anal Chem
2022
Mar 2
PubMed ID: 35234461
DOI: 10.1021/acs.analchem.1c04804
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Yamatoya K, Nagai Y, Teramoto N, Kang W, Miyado K, Nakata K, Yagi T, Miyamoto Y.
Cryopreservation of undifferentiated and differentiated human neuronal cells.
Regen Ther
2022
19:58-68
PubMed ID: 35059480
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Liu JY, Inoshita T, Shiba-Fukushima K, Yoshida S, Ogata K, Ishihama Y, Imai Y, Hattori N.
Ubiquitination at the lysine 27 residue of the parkin ubiquitin-like domain is suggestive of a new mechanism of parkin activation.
Hum Mol Genet
2022
PubMed ID: 35313349
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Liu Y, Nisisako T.
Microfluidic generation of monodispersed Janus alginate hydrogel microparticles using water-in-oil emulsion reactant.
Biomicrofluidics
2022
16(2):024101
PubMed ID: 35282035
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Fukumoto Y, Matsuhashi K, Tanaka YK, Suzuki N, Ogra Y.
Band 3/anion exchanger 1/solute carrier family 4 member 1 expression as determinant of cellular sensitivity to selenite exposure.
Biochem Biophys Rep
2022
29:101223
PubMed ID: 35146136
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Yonezawa H, Ikeda A, Takahashi R, Endo H, Sugawara Y, Goto M, Kanno M, Ogawa S, Nakamura K, Ujiie H, Iwatsuki M, Hirose T, Sunazuka T, Uehara Y, Nishiya N.
Ivermectin represses Wnt/β-catenin signaling by binding to TELO2, a regulator of phosphatidylinositol 3-kinase-related kinases.
iScience
2022
25(3):103912
PubMed ID: 35530256
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20774
Kubota Y, Fujioka Y, Patil A, Takagi Y, Matsubara D, Iijima M, Momose I, Naka R, Nakai K, Noda NN, Takekawa M.
Qualitative differences in disease-associated MEK mutants reveal molecular signatures and aberrant signaling-crosstalk in cancer.
Nat Commun
2022
13(1):4063
PubMed ID: 35831322
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Honda T, Kawasaki N, Yanagihara R, Tamura R, Murakami K, Ichimiya T, Matsumoto N, Nishihara S, Yamamoto K.
Involvement of cochlin binding to sulfated heparan sulfate/heparin in the pathophysiology of autosomal dominant late-onset hearing loss (DFNA9).
PLoS One
2022
17(7):e0268485
PubMed ID: 35901072
DOI: 10.1371/journal.pone.0268485
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Ertunc N, Phitak T, Wu D, Fujita H, Hane M, Sato C, Kitajima K.
Sulfation of sialic acid is ubiquitous and essential for vertebrate development.
Sci Rep
2022
12(1)
PubMed ID: 35864127
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20816
Krama A, Tokura N, Isoda H, Shigemori H, Miyamae Y.
Cyanidin 3-Glucoside Induces Hepatocyte Growth Factor in Normal Human Dermal Fibroblasts through the Activation of β2-Adrenergic Receptor.
ACS Omega
2022
7(26):22889-22895
PubMed ID: 35811916
DOI: 10.1021/acsomega.2c02659
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20890
Sakaguchi M, Okagawa S, Okubo Y, Otsuka Y, Fukuda K, Igata M, Kondo T, Sato Y, Yoshizawa T, Fukuda T, Yamagata K, Cai W, Tseng YH, Sakaguchi N, Kahn CR, Araki E.
Phosphatase protector alpha4 (α4) is involved in adipocyte maintenance and mitochondrial homeostasis through regulation of insulin signaling.
Nat Commun
2022
13(1):6092
PubMed ID: 36241662
DOI: 10.1038/s41467-022-33842-4
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Ito M, Maejima Y, Nishimura K, Nakae Y, Ono A, Iwaki-Egawa S.
A role for N-glycosylation in active adenosine deaminase 2 production.
Biochim Biophys Acta Gen Subj
2022
1866(12):130237
PubMed ID: 36029899
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