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13351
Matsumoto Y, Kishida K, Matsumoto M, Matsuoka S, Kohyama M, Suenaga T, Arase H.
A TCR-like antibody against a proinsulin-containing fusion peptide ameliorates type 1 diabetes in NOD mice.
Biochem Biophys Res Commun
2021
PubMed ID: 33208230
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20101
Matsuo T, Isosaka T, Hayashi Y, Tang L, Doi A, Yasuda A, Hayashi M, Lee CY, Cao L, Kutsuna N, Matsunaga S, Matsuda T, Yao I, Setou M, Kanagawa D, Higasa K, Ikawa M, Liu Q, Kobayakawa R, Kobayakawa K.
Thiazoline-related innate fear stimuli orchestrate hypothermia and anti-hypoxia via sensory TRPA1 activation.
Nat Commun
2021
12(1):2074
PubMed ID: 33824316
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20182
Takahashi K, Araki K, Miyamoto H, Shirakawa R, Yoshida T, Wakamori M.
Capsaicin and Proton Differently Modulate Activation Kinetics of Mouse Transient Receptor Potential Vanilloid-1 Channel Induced by Depolarization.
Front Pharmacol
2021
12:672157
PubMed ID: 34093200
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20187
Miki T, Nakai T, Hashimoto M, Kajiwara K, Tsutsumi H, Mihara H.
Intracellular artificial supramolecules based on de novo designed Y15 peptides.
Nat Commun
2021
12(1):3412
PubMed ID: 34099696
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20197
Ju N, Hayashi H, Shimamura M, Yoshida S, Nakamaru R, Nakagami H, Morishita R, Rakugi H.
Prevention of Acute Lung Injury by a Novel CD14-Inhibitory Receptor Activator of the NF-κB Ligand Peptide in Mice.
Immunohorizons
2021
5(6):438-447
PubMed ID: 34131020
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20217
Takashima S, Kurogochi M, Tsukimura W, Mori M, Osumi K, Sugawara SI, Amano J, Mizuno M, Takada Y, Matsuda A.
Preparation and biological activities of anti-HER2 monoclonal antibodies with multi-branched complex-type N-glycans.
Glycobiology
2021
PubMed ID: 34192331
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15439
Shams R, Matsukawa A, Ochi Y, Ito Y, Miyatake H.
In Silico and In Cell Hybrid Selection of Nonrapalog Ligands to Allosterically Inhibit the Kinase Activity of mTORC1
J Med Chem
2021
Jun 30
PubMed ID: 34191518
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15274
Yasuda K, Matsubara T, Shirakawa T, Kawamoto T, Kokabu S.
Protein phosphatase 1 regulatory subunit 18 suppresses the transcriptional activity of NFATc1 via regulation of c-fos
Bone Rep
2021
5:101114
PubMed ID: 34401407
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15284
Yoshiko Iizuka, Kinuko Inomata, Risako Nohara, Akimitsu Miyawaki and Yoshifumi Watanabe
Activation of intracellular antioxidant master gene Nrf2 by the extracts of Garcinia subelliptica, Ocimum gratissimum L., and Plectranthus ornatus
International Journal of Herbal Medicine
2021
9(3):54-60
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20357
Watanabe Y, Sugano E, Tabata K, Hatakeyama A, Sakajiri T, Fukuda T, Ozaki T, Suzuki T, Sayama T, Tomita H.
Development of an optogenetic gene sensitive to daylight and its implications in vision restoration.
NPJ Regen Med
2021
6(1):64
PubMed ID: 34650094
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15664
Tabata K, Sugano E, Hatakeyama A, Watanabe Y, Suzuki T, Ozaki T, Fukuda T, Tomita H.
Phototoxicities Caused by Continuous Light Exposure Were Not Induced in Retinal Ganglion Cells Transduced by an Optogenetic Gene
Int J Mol Sci
2021
;22(13):6732
PubMed ID: 34201658
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20417
Shams R, Ito Y, Miyatake H.
Evaluation of the Binding Kinetics of RHEB with mTORC1 by In-Cell and In Vitro Assays.
Int J Mol Sci
2021
22(16)
PubMed ID: 34445471
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20441
Hongprasit A, Okamoto Y, Toida T, Ogra Y.
Comparison of quantification of selenocyanate and thiocyanate in cultured mammalian cells between HPLC-fluorescence detector and HPLC-inductively coupled plasma mass spectrometer.
J Chromatogr B Analyt Technol Biomed Life Sci
2021
1181:122924
PubMed ID: 34508979
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6934
Baba K, Kuwada S, Nakao A, Li X, Okuda N, Nishida A, Mitsuda S, Fukuoka N, Kakeya H, Kataoka T.
Different localization of lysosomal-associated membrane protein 1 (LAMP1) in mammalian cultured cell lines.
Histochem Cell Biol
2020
PubMed ID: 31907597
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9190
Rui Jiang, Ziyan Zhang, Zhiwei Zhong, Yuxuan Dai, Guangyao Liu, Chao Zhang
Phosphorylation of Histone H4 at Serine 1 Is Associated With GCN5 and Mediates Autophagy in Osteosarcoma Bone Cell Lines
J Cell Physiol
2020
PubMed ID: 31903552
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10370
Yusuke Higuchi, Jun-Ichirou Yasunaga, Yu Mitagami, Hirotake Tsukamoto, Kazutaka Nakashima, Koichi Ohshima, Masao Matsuoka
HTLV-1 Induces T Cell Malignancy and Inflammation by Viral Antisense Factor-Mediated Modulation of the Cytokine Signaling
Proc Natl Acad Sci U S A
2020
117(24):13740-13749
PubMed ID: 32471947
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12037
Nakagawa F, Higashi S, Ando E, Ohsumi T, Watanabe S, Takeuchi H.
Modification of TRPV4 activity by acetaminophen.
Heliyon
2020
PubMed ID: 32051870
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12113
Horii T, Morita S, Hino S, Kimura M, Hino Y, Kogo H, Nakao M, Hatada I.
Successful generation of epigenetic disease model mice by targeted demethylation of the epigenome.
Genome Biol.
2020
PubMed ID: 32234052
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12360
Morita T, Akiyoshi T, Sato R, Katayama K, Yajima K, Kataoka H, Imaoka A, Sugimoto Y, Ohtani H.
pH-dependent transport kinetics of the human organic anion-transporting polypeptide 1A2
Drug Metab Pharmacokinet
2020
35(2):220-227
PubMed ID: 31974044
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13037
Ueda M, Matsuki T, Fukada M, Eda S, Toya A, Iio A, Tabata H, Nakayama A.
Knockdown of Son, a mouse homologue of the ZTTK syndrome gene, causes neuronal migration defects and dendritic spine abnormalities.
Mol Brain
2020
PubMed ID: 32448361
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13046
Ouchi K, Miyachi M, Yagyu S, Kikuchi K, Kuwahara Y, Tsuchiya K, Iehara T, Hosoi H.
Oncogenic role of HMGA2 in fusion-negative rhabdomyosarcoma cells.
Cancer Cell Int
2020
PubMed ID: 32489328
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13073
Teratani T, Tomita K, Toma-Fukai S, Nakamura Y, Itoh T, Shimizu H, Shiraishi Y, Sugihara N, Higashiyama M, Shimizu T, Inoue I, Takenaka Y, Hokari R, Adachi T, Shimizu T, Miura S, Kanai T.
Redox-dependent PPARγ/Tnpo1 complex formation enhances PPARγ nuclear localization and signaling.
Free Radic Biol Med
2020
PubMed ID: 32553752
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13095
Mai NNH, Yamaguchi Y, Choijookhuu N, Matsumoto J, Nanashima A, Takagi H, Sato K, Tuan LQ, Hishikawa Y.
Photodynamic Therapy Using a Novel Phosphorus Tetraphenylporphyrin Induces an Anticancer Effect via Bax/Bcl-xL-related Mitochondrial Apoptosis in Biliary Cancer Cells.
Acta Histochem Cytochem
2020
PubMed ID: 32873990
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13115
Urabe T, Yanase Y, Motoike S, Harada K, Hide I, Tanaka S, Tsutsumi YM, Kawamoto M, Sakai N.
Propofol induces the elevation of intracellular calcium via morphological changes in intracellular organelles, including the endoplasmic reticulum and mitochondria.
Eur J Pharmacol
2020
PubMed ID: 32681942
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13163
Furuno K, Wang J, Suzuki K, Nakahata M, Sakai S.
Gelatin-Based Electrospun Fibers Insolubilized by Horseradish Peroxidase-Catalyzed Cross-Linking for Biomedical Applications.
ACS Omega
2020
PubMed ID: 32875262
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13193
Iio A, Kaji K, Kaji N, Hori M, Yonezawa T, Momoi Y, Maeda S.
Expression analysis of protease-activated receptor-2 in cats.
Vet Immunol Immunopathol
2020
PubMed ID: 32932190
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13200
Ago Y, Otsuka H, Sasai H, Abdelkreem E, Nakama M, Aoyama Y, Matsumoto H, Fujiki R, Ohara O, Akiyama K, Fukui K, Watanabe Y, Nakajima Y, Ohnishi H, Ito T, Fukao T.
Japanese patients with mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase deficiency: In vitro functional analysis of five novel HMGCS2 mutations.
Exp Ther Med
2020
PubMed ID: 32952630
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13307
Yanaizu M, Washizu C, Nukina N, Satoh JI, Kino Y.
CELF2 regulates the species-specific alternative splicing of TREM2.
Sci Rep
2020
PubMed ID: 33093587
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13349
Konishi H, Hayashi M, Taniguchi K, Nakamura M, Kuranaga Y, Ito Y, Kondo Y, Sasaki H, Terai Y, Akao Y, Ohmichi M.
The therapeutic potential of exosomal miR-22 for cervical cancer radiotherapy.
Cancer Biol Ther
2020
PubMed ID: 33190594
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13584
Uda RM, Yoshida N, Iwasaki T, Hayashi K.
pH-triggered solubility and cytotoxicity changes of malachite green derivatives incorporated in liposomes for killing cancer cells
J Mater Chem B
2020
8(36):8242-8248
PubMed ID: 32794526
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13610
Puteri MU, Watanabe Y, Wardhani BWK, Amalia R, Abdelaziz M, Kato M.
PMEPA1/TMEPAI isoforms function via its PY and Smad-interaction motifs for tumorigenic activities of breast cancer cells
Genes Cells
2020
25(6):375-390
PubMed ID: 32181976
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13944
Akaike Y, Chibazakura T.
Aberrant activation of cyclin A-CDK induces G2/M-phase checkpoint in human cells
Cell Cycle
2020
19(1):84-96
PubMed ID: 31760882
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14836
Punzalan LL, Jiang L, Mao D, Mahapatra AD, Sato S, Takemoto Y, Tsujimura M, Kusamori K, Nishikawa M, Zhou L, Uesugi M.
Chemoproteomic Profiling of a Pharmacophore-Focused Chemical Library
Cell Chem Biol
2020
27(6):708-718.e1
PubMed ID: 32402240
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20272
Ma Y, Yoshida T, Matoba K, Kida K, Shintani R, Piao Y, Jin J, Nishino T, Hanayama R.
Identification of small compounds regulating the secretion of extracellular vesicles via a TIM4-affinity ELISA.
Sci Rep
2020
11(1):13471
PubMed ID: 34188113
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11179
Ali F, Hossain MS, Sejimo S, Akashi K.
Plasmalogens Inhibit Endocytosis of Toll-like Receptor 4 to Attenuate the Inflammatory Signal in Microglial Cells.
Mol. Neurobiol.
2019
56(5):3404-3419
PubMed ID: 30128650
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4052
Kidoya H, Muramatsu F, Shimamura T, Jia W, Satoh T, Hayashi Y, Naito H, Kunisaki Y, Arai F, Seki M, Suzuki Y, Osawa T, Akira S, Takakura N.
Regnase-1-mediated post-transcriptional regulation is essential for hematopoietic stem and progenitor cell homeostasis
Nat Commun
2019
10:1072
PubMed ID: 30842549
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11312
Manabe A, Furukawa C, Hasegawa H, Matsunaga T, Endo S, Ikari A.
Upregulation of transient receptor potential melastatin 6 channel expression by rosiglitazone and all-trans-retinoic acid in erlotinib-treated renal tubular epithelial cells.
J. Cell. Physiol.
2019
PubMed ID: 30461012
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11394
Hayashi M, Nakashima T, Yoshimura N, Okamoto K, Tanaka S, Takayanagi H.
Autoregulation of Osteocyte Sema3A Orchestrates Estrogen Action and Counteracts Bone Aging.
Cell Metab.
2019
PubMed ID: 30661929
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11402
Morita M, Hashimoto O.
Identification and expression of the medaka inhibin βE subunit.
Mol. Biol. Rep.
2019
PubMed ID: 30680594
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11412
Zhang W, Matsuo R, Takahara T, Shibata H, Maki M.
High Sensitive Quantitative Binding Assays Using a Nanoluciferase-Fused Probe for Analysis of ALG-2-Interacting Proteins.
Methods Mol. Biol.
2019
PubMed ID: 30710293
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11411
Zhang W, Takahara T, Achiha T, Shibata H, Maki M.
Cellular Ca2+-Responding Nanoluciferase Reporter Gene System Directed by Tandemly Repeated Pseudo-palindromic NFAT-Response Elements.
Methods Mol. Biol.
2019
PubMed ID: 30710269
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6050
Yokota S, Kuramochi H, Okubo K, Iwaya A, Tsuchiya S, Ichiki T.
Extracellular vesicles nanoarray technology: Immobilization of individual extracellular vesicles on nanopatterned polyethylene glycol-lipid conjugate brushes.
PLoS One
2019
14(10):e0224091
PubMed ID: 31648253
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11580
Tanaka J, Mabuchi Y, Hata K, Yasuhara R, Takamatsu K, Kujiraoka S, Yukimori A, Takakura I, Sumimoto H, Fukada T, Azuma M, Akiyama H, Nishimura R, Shimane T, Mishima K.
Sox9 regulates the luminal stem/progenitor cell properties of salivary glands.
Exp. Cell Res.
2019
PubMed ID: 31153924
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11586
Ikeda Y, Morita SY, Hatano R, Tsuji T, Terada T.
Enhancing effect of taurohyodeoxycholate on ABCB4-mediated phospholipid efflux.
Biochim Biophys Acta Mol Cell Biol Lipids
2019
PubMed ID: 31176036
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11628
Mitsui E, Yoshida S, Shinoda Y, Matsumori Y, Tsujii H, Tsuchida M, Wada S, Hasegawa M, Ito A, Mino K, Onuki T, Yoshida M, Sasaki R, Mizukami T.
Identification of ryuvidine as a KDM5A inhibitor.
Sci Rep
2019
PubMed ID: 31289306
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11800
Koizumi A, Narita S, Nakanishi H, Ishikawa M, Eguchi S, Kimura H, Takasuga S, Huang M, Inoue T, Sasaki J, Yoshioka T, Habuchi T, Sasaki T.
Increased fatty acyl saturation of phosphatidylinositol phosphates in prostate cancer progression.
Sci Rep
2019
PubMed ID: 31520002
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6899
Miyano K, Shiraishi S, Minami, Sudo Y, Suzuki M, Yokoyama T, Terawaki K, Nonaka M, Murata H, Higami Y, Uezono Y.
Carboplatin Enhances the Activity of Human Transient Receptor Potential Ankyrin 1 through the Cyclic AMP-Protein Kinase A-A-Kinase Anchoring Protein (AKAP) Pathways.
Int J Mol Sci
2019
20(13):3271
PubMed ID: 31277262
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6937
Ryo Muko et al
Cloning and Detection of Equine Histidine-Rich Glycoprotein
Journal of Equine Veterinary Science
2019
73:121-126
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10396
Takahiro Toda, Shinichiro Yamamoto, Noriko Umehara, Yasuo Mori, Minoru Wakamori, Shunichi Shimizu
Protective Effects of Duloxetine Against Cerebral Ischemia-Reperfusion Injury via Transient Receptor Potential Melastatin 2 Inhibition
J Pharmacol Exp Ther
2019
368(2):246-254
PubMed ID: 30523061
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10397
Murat Kutluay, Makoto Inoue and Iclal Saracoglu
Assessment of LXRα agonist activity and selective antiproliferative efficacy: a study on different parts of Digitalis species
Turkish Journal of Biochemistry
2019
44
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10400
Shun Adachi
Induction of hierarchy and time through one-dimensional probability space with certain topologies
bioRxiv
2019
September 24
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12328
Ikeda T, Ichikawa K, Shigeto H, Ishida T, Hirota R, Funabashi H, Kuroda A.
Arginine-mediated dissociation of single cells and cell sheets from a polystyrene culture dish
Biosci Biotechnol Biochem
2019
83(12):2272-2275
PubMed ID: 31482750
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12353
Li J, Yoshida Y, Kurita M, Usuki T.
Cynaropicrin and inhibition of NF-κB activation: A structure activity relationship study
Bioorg Med Chem Lett
2019
29(12):1518-1521
PubMed ID: 30987894
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12359
Nakai S, Uchitomi R, Matsuda R, Onishi T, Hatazawa Y, Kamei Y.
Screening dataset of food components that enhance transcriptional activity of PGC1-beta
Data Brief
2019
23:103814
PubMed ID: 31372459
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12361
Fujita S, Hirota T, Sakiyama R, Baba M, Ieiri I.
Identification of drug transporters contributing to oxaliplatin-induced peripheral neuropathy
J Neurochem
2019
148(3):373-385
PubMed ID: 30295925
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7018
Uchida S, Yoshinaga N, Yanagihara K, Yuba E, Kataoka K, Itaka K.
Designing immunostimulatory double stranded messenger RNA with maintained translational activity through hybridization with poly A sequences for effective vaccination.
Biomaterials
2018
150:162-170
PubMed ID: 29031816
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9502
Morita M, Sato T, Nomura M, Sakamoto Y, Inoue Y, Tanaka R, Ito S, Kurosawa K, Yamaguchi K, Sugiura Y, Takizaki H, Yamashita Y, Katakura R, Sato I, Kawai M, Okada Y, Watanabe H, Kondoh G, Matsumoto S, Kishimoto A, Obata M, Matsumoto M, Fukuhara T, Motohashi H, Suematsu M, Komatsu M, Nakayama KI, Watanabe T, Soga T, Shima H, Maemondo M, Tanuma N.
PKM1 Confers Metabolic Advantages and Promotes Cell-Autonomous Tumor Cell Growth.
Cancer Cell
2018
33:355-367.e7
PubMed ID: 29533781
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10620
Nakamura M, Fujita K, Toyoda Y, Takada T, Hasegawa H, Ichida K.
Investigation of the transport of xanthine dehydrogenase inhibitors by the urate transporter ABCG2.
Drug Metab. Pharmacokinet.
2018
33:77-81
PubMed ID: 29342419
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11076
Toyama K, Nomura W, Kobayakawa T, Tamamura H.
Delivery of a Proapoptotic Peptide to EGFR-Positive Cancer Cells by a Cyclic Peptide Mimicking the Dimerization Arm Structure of EGFR.
Bioconjug. Chem.
2018
29(6):2050-2057
PubMed ID: 29763296
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11083
Tsuchiya M, Hara Y, Okuda M, Itoh K, Nishioka R, Shiomi A, Nagao K, Mori M, Mori Y, Ikenouchi J, Suzuki R, Tanaka M, Ohwada T, Aoki J, Kanagawa M, Toda T, Nagata Y, Matsuda R, Takayama Y, Tominaga M, Umeda M.
Cell surface flip-flop of phosphatidylserine is critical for PIEZO1-mediated myotube formation.
Nat Commun
2018
9(1):2049
PubMed ID: 29799007
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11158
Matsumoto S, Caliskan N, Rodnina MV, Murata A, Nakatani K.
Small synthetic molecule-stabilized RNA pseudoknot as an activator for -1 ribosomal frameshifting.
Nucleic Acids Res.
2018
46(16):8079-8089
PubMed ID: 30085309
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11074
Tsukamoto H, Takeuchi S, Kubota K, Kobayashi Y, Kozakai S, Ukai I, Shichiku A, Okubo M, Numasaki M, Kanemitsu Y, Matsumoto Y, Nochi T, Watanabe K, Aso H, Tomioka Y.
Lipopolysaccharide (LPS)-binding protein stimulates CD14-dependent Toll-like receptor 4 internalization and LPS-induced TBK1-IKK?-IRF3 axis activation.
J. Biol. Chem.
2018
293(26):10186-10201
PubMed ID: 29760187
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11164
Mogi K, Hayashida K, Yamamoto T.
Damage-less Handling of Exosomes Using an Ion-depletion Zone in a Microchannel.
Anal Sci
2018
34(8):875-880
PubMed ID: 30101880
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11260
Fujita D, Arai T, Komori H, Shirasaki Y, Wakayama T, Nakanishi T, Tamai I.
Apple-Derived Nanoparticles Modulate Expression of Organic-Anion-Transporting Polypeptide (OATP) 2B1 in Caco-2 Cells.
Mol. Pharm.
2018
PubMed ID: 30359033
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11268
Hashimoto O, Funaba M, Sekiyama K, Doi S, Shindo D, Satoh R, Itoi H, Oiwa H, Morita M, Suzuki C, Sugiyama M, Yamakawa N, Takada H, Matsumura S, Inoue K, Oyadomari S, Sugino H, Kurisaki A.
Activin E Controls Energy Homeostasis in Both Brown and White Adipose Tissues as a Hepatokine.
Cell Rep
2018
PubMed ID: 30380411
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11399
Ohara M, Ohnishi S, Hosono H, Yamamoto K, Yuyama K, Nakamura H, Fu Q, Maehara O, Suda G, Sakamoto N.
Extracellular Vesicles from Amnion-Derived Mesenchymal Stem Cells Ameliorate Hepatic Inflammation and Fibrosis in Rats.
Stem Cells Int
2018
PubMed ID: 30675167
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4085
Agata Okonska et al
Genome-wide silencing screen in mesothelioma cells reveals that loss of function of BAP1 induces chemoresistance to ribonucleotide reductase inhibition: implication for therapy
bioRxiv
2018
July 31
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4101
Takagi M, Kimura K, Nakashima KI, Inoue M.
Ameliorative effect of panaxynol on the reduction in high-molecular-weight adiponectin secretion from 3T3-L1 adipocytes treated with palmitic acids.
Eur. J. Pharmacol.
2018
PubMed ID: 29248425
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4102
Kanamoto M, Tsuchiya Y, Nakao Y, Suzuki T, Motohashi H, Yamamoto M, Kamata H.
Structural instability of IκB kinase β promotes autophagic degradation through enhancement of Keap1 binding.
PLoS ONE
2018
PubMed ID: 30500824
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|
4103
Ohara M, Ohnishi S, Hosono H, Yamamoto K, Fu Q, Maehara O, Suda G, Sakamoto N.
Palmitoylethanolamide Ameliorates Carbon Tetrachloride-Induced Liver Fibrosis in Rats.
Front Pharmacol
2018
PubMed ID: 30057547
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4104
Mizuno H, Taketomi A.
MicroRNA-101 inhibits the expression of Rhes, a striatal-enriched small G-protein, at the post-transcriptional level in vitro.
BMC Res Notes
2018
PubMed ID: 30064488
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4105
Takayama-Ito M, Lim CK, Yamaguchi Y, Posadas-Herrera G, Kato H, Iizuka I, Islam MT, Morimoto K, Saijo M.
Replication-incompetent rabies virus vector harboring glycoprotein gene of lymphocytic choriomeningitis virus (LCMV) protects mice from LCMV challenge.
PLoS Negl Trop Dis
2018
PubMed ID: 29659579
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4106
Saifullah, Tsukahara T.
Genotyping of single nucleotide polymorphisms using the SNP-RFLP method.
Biosci Trends
2018
PubMed ID: 30012914
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4107
Nishiyama Y, Fujii S, Makishima M, Hashimoto Y, Ishikawa M.
Efficient Lead Finding, Activity Enhancement and Preliminary Selectivity Control of Nuclear Receptor Ligands Bearing a Phenanthridinone Skeleton.
Int J Mol Sci
2018
PubMed ID: 30021999
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4108
Matsuura M, Ohshima M, Hiruta Y, Nishimura T, Nagase K, Kanazawa H.
LAT1-Targeting Thermoresponsive Fluorescent Polymer Probes for Cancer Cell Imaging.
Int J Mol Sci
2018
PubMed ID: 29865203
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14542
Matsubara T, Kokabu S, Nakatomi C, Kinbara M, Maeda T, Yoshizawa M, Yasuda H, Takano-Yamamoto T, Baron R, Jimi E.
The Actin-Binding Protein PPP1r18 Regulates Maturation, Actin Organization, and Bone Resorption Activity of Osteoclasts
Mol Cell Biol
2018
38(4):e00425-17
PubMed ID: 29158294
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14701
Otero R, Ishizawa M, Numoto N, Ikura T, Ito N, Tokiwa H, Mouriño A, Makishima M, Yamada S.
25 S-Adamantyl-23-yne-26,27-dinor-1α,25-dihydroxyvitamin D 3: Synthesis, Tissue Selective Biological Activities, and X-ray Crystal Structural Analysis of Its Vitamin D Receptor Complex
J Med Chem
2018
61(15):6658-6673
PubMed ID: 29989817
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14895
Cheng CC, Tsutsui K, Taguchi T, Sanzen N, Nakagawa A, Kakiguchi K, Yonemura S, Tanegashima C, Keeley SD, Kiyonari H, Furuta Y, Tomono Y, Watt FM, Fujiwara H.
Hair follicle epidermal stem cells define a niche for tactile sensation
Elife
2018
7:e38883
PubMed ID: 30355452
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9982
Furukawa C, Fujii N, Manabe A, Matsunaga T, Endo S, Hasegawa H, Ito Y, Yamaguchi M, Yamazaki Y, Ikari A.
Up-Regulation of Transient Receptor Potential Melastatin 6 Channel Expression by Tumor Necrosis Factor-α in the Presence of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor.
J. Cell. Physiol.
2017
232:2841-2850
PubMed ID: 27925186
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9983
Imaizumi Y, Goda T, Schaffhauser DF, Okada JI, Matsumoto A, Miyahara Y.
Proton-sensing transistor systems for detecting ion leakage from plasma membranes under chemical stimuli.
Acta Biomater
2017
50:502-509
PubMed ID: 27956364
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10079
Satou K, Mochimaru Y, Nakakura T, Kusada T, Negishi J, Musha S, Yoshimura N, Kato Y, Tomura H.
Easy detection of hormone secretion from LβT2 cells by using Gaussia luciferase.
J. Reprod. Dev.
2017
63:199-204
PubMed ID: 28090002
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10393
Yukimori A, Oikawa Y, Morita KI, Nguyen CTK, Harada H, Yamaguchi S, Kayamori K, Yamaguchi A, Ikeda T, Sakamoto K.
Genetic basis of calcifying cystic odontogenic tumors.
PLoS ONE
2017
12:e0180224
PubMed ID: 28658279
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10416
Kubota Y, Fujioka K, Takekawa M.
WGA-based lectin affinity gel electrophoresis: A novel method for the detection of O-GlcNAc-modified proteins.
PLoS ONE
2017
12:e0180714
PubMed ID: 28686627
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10433
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Int J Mol Med
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Mechanisms underlying the toxic effects of antimony species in human embryonic kidney cells (HEK-293) and their comparison with arsenic species
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Development of a highly reproducible system to evaluate inhibition of cytochrome P450 3A4 activity by natural medicines.
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Efficacy of Recombinant Canine Distemper Virus Expressing Leishmania Antigen against Leishmania Challenge in Dogs.
PLoS Negl Trop Dis
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Bruton's tyrosine kinase is essential for NLRP3 inflammasome activation and contributes to ischaemic brain injury.
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An improved superoxide-generating nanodevice for oxidative stress studies in cultured cells.
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Michiko Yoshida, Kenji Hata, Rikako Takashima, Koichiro Ono, Eriko Nakamura, Yoshifumi Takahata, Tomohiko Murakami, Sachiko Iseki, Teruko Takano-Yamamoto, Riko Nishimura, Toshiyuki Yoneda
The Transcription Factor Foxc1 Is Necessary for Ihh-Gli2-regulated Endochondral Ossification
Nat Commun
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Koichi Fujikawa, Ryo Fukumori, Saki Nakamura, Takaya Kutsukake, Takeshi Takarada, Yukio Yoneda
Potential Interactions of Calcium-Sensitive Reagents With Zinc Ion in Different Cultured Cells
PLoS One
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Efficient delivery to human lung fibroblasts (WI-38) of pirfenidone incorporated into liposomes modified with truncated basic fibroblast growth factor and its inhibitory effect on collagen synthesis in idiopathic pulmonary fibrosis.
Biol Pharm Bull
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Dominant mutations in ORAI1 cause tubular aggregate myopathy with hypocalcemia via constitutive activation of store-operated Ca²⁺ channels
Hum Mol Genet
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Ohsawa Y, Takayama K, Nishimatsu S, Okada T, Fujino M, Fukai Y, Murakami T, Hagiwara H, Itoh F, Tsuchida K, Hayashi Y, Sunada Y.
The Inhibitory Core of the Myostatin Prodomain: Its Interaction with Both Type I and II Membrane Receptors, and Potential to Treat Muscle Atrophy
PLoS One
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Raster image cross-correlation analysis for spatiotemporal visualization of intracellular degradation activities against exogenous DNAs
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Narita K, Sasamoto S, Koizumi S, Okazaki S, Nakamura H, Inoue T, Takeda S.
TRPV4 regulates the integrity of the blood-cerebrospinal fluid barrier and modulates transepithelial protein transport
FASEB J
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Tamura M, Kawano M, Sato M, Nashimoto M.
Involvement of an intracellular vesicular transport process in naked-sgRNA-mediated TRUE gene silencing
Mol Med Rep
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Yusuke Watarai, Michiyasu Ishizawa, Teikichi Ikura, Flavia C. M. Zacconi, Shigeyuki Uno, Nobutoshi Ito, Antonio Mouriño, Hiroaki Tokiwa, Makoto Makishima, Sachiko Yamada
Synthesis, Biological Activities, and X-ray Crystal Structural Analysis of 25-Hydroxy-25(or 26)-adamantyl-17-[20(22),23-diynyl]-21-norvitamin D Compounds
Journal of Medicinal Chemistry
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Acetylcholinesterase overexpression mediated by oncolytic adenovirus exhibited potent anti-tumor effect.
BMC Cancer
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Shimizu S, Yonezawa R, Hagiwara T, Yoshida T, Takahashi N, Hamano S, Negoro T, Toda T, Wakamori M, Mori Y, Ishii M.
Inhibitory effects of AG490 on H2O2-induced TRPM2-mediated Ca(2+) entry.
Eur J Pharmacol
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Mutsuyo Takayama-Ito, Kazuo Nakamichi, Hitomi Kinoshita, Satsuki Kakiuchi, Ichiro Kurane, Masayuki Saijo, Chang-Kweng Lim
A Sensitive in Vitro Assay for the Detection of Residual Viable Rabies Virus in Inactivated Rabies Vaccines
Biologicals
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Kazuhiro Shiozaki, Sena Ryuzono, Naoto Matsushita, Asami Ikeda, Kazuki Takeshita, Petros Kingstone Chigwechokha, Masaharu Komatsu, Taeko Miyagi
Molecular Cloning and Biochemical Characterization of Medaka (Oryzias Latipes) Lysosomal neu4 Sialidase
Fish Physiol Biochemc
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40(5):1461-72
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Petros Kingstone Chigwechokha, Masaharu Komatsu, Takao Itakura, Kazuhiro Shiozaki
Nile Tilapia Neu3 Sialidases: Molecular Cloning, Functional Characterization and Expression in Oreochromis Niloticus
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Rexinoids isolated from Sophora tonkinensis with a gene expression profile distinct from the synthetic rexinoid bexarotene
J Nat Prod
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Identification and characterization of cryptochrome4 in the ovary of western clawed frog Xenopus tropicalis
Zoolog Sci
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Molecular cloning and biochemical characterization of two novel Neu3 sialidases, neu3a and neu3b, from medaka (Oryzias latipes).
Biochimie
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Syed Ahmed, Jinhua Dong, Megumi Yui, Tatsuya Kato, Jaebeom Lee, Enoch Y Park
Quantum Dots Incorporated Magnetic Nanoparticles for Imaging Colon Carcinoma Cells
J Nanobiotechnology
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Ohnishi S, Maehara O, Nakagawa K, Kameya A, Otaki K, Fujita H, Higashi R, Takagi K, Asaka M, Sakamoto N, Kobayashi M, Takeda H.
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Tanaka T, Okada M, Hozumi Y, Tachibana K, Kitanaka C, Hamamoto Y, Martelli AM, Topham MK, Iino M, Goto K.
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Brain-derived neurotrophic factor receptor TrkB exists as a preformed dimer in living cells.
J Mol Signal
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Neurochem Int
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A naturally occurring rexinoid, honokiol, can serve as a regulator of various retinoid x receptor heterodimers
Biol Pharm Bull
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BRCA1 regulates microRNA biogenesis via the DROSHA microprocessor complex
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Pioglitazone enhances cholesterol efflux from macrophages by increasing ABCA1/ABCG1 expressions via PPARγ/LXRα pathway: findings from in vitro and ex vivo studies.
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J Control Release
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BMC Mol Biol
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