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15439
Shams R, Matsukawa A, Ochi Y, Ito Y, Miyatake H.
In Silico and In Cell Hybrid Selection of Nonrapalog Ligands to Allosterically Inhibit the Kinase Activity of mTORC1
J Med Chem
2022
Jun 30
PubMed ID: 34191518
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20553
Urabe T, Miyoshi H, Narasaki S, Yanase Y, Uchida K, Noguchi S, Hide M, Tsutsumi YM, Sakai N.
Characterization of intracellular calcium mobilization induced by remimazolam, a newly approved intravenous anesthetic.
PLoS One
2022
17(2):e0263395
PubMed ID: 35104283
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16391
Sakamoto T, Yu Z, Otani Y.
Dual-Color Fluorescence Switch-On Probe for Imaging G-Quadruplex and Double-Stranded DNA in Living Cells
Anal Chem
2022
Mar 2
PubMed ID: 35234461
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20612
Yamatoya K, Nagai Y, Teramoto N, Kang W, Miyado K, Nakata K, Yagi T, Miyamoto Y.
Cryopreservation of undifferentiated and differentiated human neuronal cells.
Regen Ther
2022
19:58-68
PubMed ID: 35059480
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20616
Liu JY, Inoshita T, Shiba-Fukushima K, Yoshida S, Ogata K, Ishihama Y, Imai Y, Hattori N.
Ubiquitination at the lysine 27 residue of the parkin ubiquitin-like domain is suggestive of a new mechanism of parkin activation.
Hum Mol Genet
2022
PubMed ID: 35313349
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20649
Liu Y, Nisisako T.
Microfluidic generation of monodispersed Janus alginate hydrogel microparticles using water-in-oil emulsion reactant.
Biomicrofluidics
2022
16(2):024101
PubMed ID: 35282035
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20657
Fukumoto Y, Matsuhashi K, Tanaka YK, Suzuki N, Ogra Y.
Band 3/anion exchanger 1/solute carrier family 4 member 1 expression as determinant of cellular sensitivity to selenite exposure.
Biochem Biophys Rep
2022
29:101223
PubMed ID: 35146136
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20701
Yonezawa H, Ikeda A, Takahashi R, Endo H, Sugawara Y, Goto M, Kanno M, Ogawa S, Nakamura K, Ujiie H, Iwatsuki M, Hirose T, Sunazuka T, Uehara Y, Nishiya N.
Ivermectin represses Wnt/β-catenin signaling by binding to TELO2, a regulator of phosphatidylinositol 3-kinase-related kinases.
iScience
2022
25(3):103912
PubMed ID: 35530256
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20774
Kubota Y, Fujioka Y, Patil A, Takagi Y, Matsubara D, Iijima M, Momose I, Naka R, Nakai K, Noda NN, Takekawa M.
Qualitative differences in disease-associated MEK mutants reveal molecular signatures and aberrant signaling-crosstalk in cancer.
Nat Commun
2022
13(1):4063
PubMed ID: 35831322
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20796
Honda T, Kawasaki N, Yanagihara R, Tamura R, Murakami K, Ichimiya T, Matsumoto N, Nishihara S, Yamamoto K.
Involvement of cochlin binding to sulfated heparan sulfate/heparin in the pathophysiology of autosomal dominant late-onset hearing loss (DFNA9).
PLoS One
2022
17(7):e0268485
PubMed ID: 35901072
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20807
Ertunc N, Phitak T, Wu D, Fujita H, Hane M, Sato C, Kitajima K.
Sulfation of sialic acid is ubiquitous and essential for vertebrate development.
Sci Rep
2022
12(1)
PubMed ID: 35864127
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20816
Krama A, Tokura N, Isoda H, Shigemori H, Miyamae Y.
Cyanidin 3-Glucoside Induces Hepatocyte Growth Factor in Normal Human Dermal Fibroblasts through the Activation of β2-Adrenergic Receptor.
ACS Omega
2022
7(26):22889-22895
PubMed ID: 35811916
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20101
Matsuo T, Isosaka T, Hayashi Y, Tang L, Doi A, Yasuda A, Hayashi M, Lee CY, Cao L, Kutsuna N, Matsunaga S, Matsuda T, Yao I, Setou M, Kanagawa D, Higasa K, Ikawa M, Liu Q, Kobayakawa R, Kobayakawa K.
Thiazoline-related innate fear stimuli orchestrate hypothermia and anti-hypoxia via sensory TRPA1 activation.
Nat Commun
2021
12(1):2074
PubMed ID: 33824316
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20182
Takahashi K, Araki K, Miyamoto H, Shirakawa R, Yoshida T, Wakamori M.
Capsaicin and Proton Differently Modulate Activation Kinetics of Mouse Transient Receptor Potential Vanilloid-1 Channel Induced by Depolarization.
Front Pharmacol
2021
12:672157
PubMed ID: 34093200
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20187
Miki T, Nakai T, Hashimoto M, Kajiwara K, Tsutsumi H, Mihara H.
Intracellular artificial supramolecules based on de novo designed Y15 peptides.
Nat Commun
2021
12(1):3412
PubMed ID: 34099696
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20197
Ju N, Hayashi H, Shimamura M, Yoshida S, Nakamaru R, Nakagami H, Morishita R, Rakugi H.
Prevention of Acute Lung Injury by a Novel CD14-Inhibitory Receptor Activator of the NF-κB Ligand Peptide in Mice.
Immunohorizons
2021
5(6):438-447
PubMed ID: 34131020
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20217
Takashima S, Kurogochi M, Tsukimura W, Mori M, Osumi K, Sugawara SI, Amano J, Mizuno M, Takada Y, Matsuda A.
Preparation and biological activities of anti-HER2 monoclonal antibodies with multi-branched complex-type N-glycans.
Glycobiology
2021
PubMed ID: 34192331
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20272
Ma Y, Yoshida T, Matoba K, Kida K, Shintani R, Piao Y, Jin J, Nishino T, Hanayama R.
Identification of small compounds regulating the secretion of extracellular vesicles via a TIM4-affinity ELISA.
Sci Rep
2021
11(1):13471
PubMed ID: 34188113
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15274
Yasuda K, Matsubara T, Shirakawa T, Kawamoto T, Kokabu S.
Protein phosphatase 1 regulatory subunit 18 suppresses the transcriptional activity of NFATc1 via regulation of c-fos
Bone Rep
2021
5:101114
PubMed ID: 34401407
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15284
Yoshiko Iizuka, Kinuko Inomata, Risako Nohara, Akimitsu Miyawaki and Yoshifumi Watanabe
Activation of intracellular antioxidant master gene Nrf2 by the extracts of Garcinia subelliptica, Ocimum gratissimum L., and Plectranthus ornatus
International Journal of Herbal Medicine
2021
9(3):54-60
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20357
Watanabe Y, Sugano E, Tabata K, Hatakeyama A, Sakajiri T, Fukuda T, Ozaki T, Suzuki T, Sayama T, Tomita H.
Development of an optogenetic gene sensitive to daylight and its implications in vision restoration.
NPJ Regen Med
2021
6(1):64
PubMed ID: 34650094
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15664
Tabata K, Sugano E, Hatakeyama A, Watanabe Y, Suzuki T, Ozaki T, Fukuda T, Tomita H.
Phototoxicities Caused by Continuous Light Exposure Were Not Induced in Retinal Ganglion Cells Transduced by an Optogenetic Gene
Int J Mol Sci
2021
;22(13):6732
PubMed ID: 34201658
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20417
Shams R, Ito Y, Miyatake H.
Evaluation of the Binding Kinetics of RHEB with mTORC1 by In-Cell and In Vitro Assays.
Int J Mol Sci
2021
22(16)
PubMed ID: 34445471
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20441
Hongprasit A, Okamoto Y, Toida T, Ogra Y.
Comparison of quantification of selenocyanate and thiocyanate in cultured mammalian cells between HPLC-fluorescence detector and HPLC-inductively coupled plasma mass spectrometer.
J Chromatogr B Analyt Technol Biomed Life Sci
2021
1181:122924
PubMed ID: 34508979
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15887
See K, Kadonosono T, Miyamoto K, Tsubaki T, Ota Y, Katsumi M, Ryo S, Aida K, Minegishi M, Isozaki T, Kuchimaru T, Kizaka-Kondoh S.
Antibody-guided design and identification of CD25-binding small antibody mimetics using mammalian cell surface display
Sci Rep
2021
11(1):22098
PubMed ID: 34764369
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16832
Nakanishi T, Maekawa A, Suzuki M, Tabata H, Sato K, Mori M, Saito I.
Construction of adenovirus vectors simultaneously expressing four multiplex, double-nicking guide RNAs of CRISPR/Cas9 and in vivo genome editing
Sci Rep
2021
11(1):3961
PubMed ID: 33597562
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16860
Akaike Y, Nakane Y, Chibazakura T.
Analysis of E1A domains involved in the enhancement of CDK2 activity
Biochem Biophys Res Commun
2021
548:98-103
PubMed ID: 33640611
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6934
Baba K, Kuwada S, Nakao A, Li X, Okuda N, Nishida A, Mitsuda S, Fukuoka N, Kakeya H, Kataoka T.
Different localization of lysosomal-associated membrane protein 1 (LAMP1) in mammalian cultured cell lines.
Histochem Cell Biol
2020
PubMed ID: 31907597
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9190
Rui Jiang, Ziyan Zhang, Zhiwei Zhong, Yuxuan Dai, Guangyao Liu, Chao Zhang
Phosphorylation of Histone H4 at Serine 1 Is Associated With GCN5 and Mediates Autophagy in Osteosarcoma Bone Cell Lines
J Cell Physiol
2020
PubMed ID: 31903552
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9738
Kanano Kitamura, Jane Surya Erlangga, Sakuka Tsukamoto, Yuri Sakamoto, Hideaki Mabashi-Asazuma, Kaoruko Iida
Daidzein Promotes the Expression of Oxidative Phosphorylation- And Fatty Acid Oxidation-Related Genes via an Estrogen-Related Receptor α Pathway to Decrease Lipid Accumulation in Muscle Cells
J Nutr Biochem
2020
77:108315
PubMed ID: 31923756
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10370
Yusuke Higuchi, Jun-Ichirou Yasunaga, Yu Mitagami, Hirotake Tsukamoto, Kazutaka Nakashima, Koichi Ohshima, Masao Matsuoka
HTLV-1 Induces T Cell Malignancy and Inflammation by Viral Antisense Factor-Mediated Modulation of the Cytokine Signaling
Proc Natl Acad Sci U S A
2020
117(24):13740-13749
PubMed ID: 32471947
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12037
Nakagawa F, Higashi S, Ando E, Ohsumi T, Watanabe S, Takeuchi H.
Modification of TRPV4 activity by acetaminophen.
Heliyon
2020
PubMed ID: 32051870
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12113
Horii T, Morita S, Hino S, Kimura M, Hino Y, Kogo H, Nakao M, Hatada I.
Successful generation of epigenetic disease model mice by targeted demethylation of the epigenome.
Genome Biol.
2020
PubMed ID: 32234052
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12360
Morita T, Akiyoshi T, Sato R, Katayama K, Yajima K, Kataoka H, Imaoka A, Sugimoto Y, Ohtani H.
pH-dependent transport kinetics of the human organic anion-transporting polypeptide 1A2
Drug Metab Pharmacokinet
2020
35(2):220-227
PubMed ID: 31974044
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13037
Ueda M, Matsuki T, Fukada M, Eda S, Toya A, Iio A, Tabata H, Nakayama A.
Knockdown of Son, a mouse homologue of the ZTTK syndrome gene, causes neuronal migration defects and dendritic spine abnormalities.
Mol Brain
2020
PubMed ID: 32448361
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13046
Ouchi K, Miyachi M, Yagyu S, Kikuchi K, Kuwahara Y, Tsuchiya K, Iehara T, Hosoi H.
Oncogenic role of HMGA2 in fusion-negative rhabdomyosarcoma cells.
Cancer Cell Int
2020
PubMed ID: 32489328
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13073
Teratani T, Tomita K, Toma-Fukai S, Nakamura Y, Itoh T, Shimizu H, Shiraishi Y, Sugihara N, Higashiyama M, Shimizu T, Inoue I, Takenaka Y, Hokari R, Adachi T, Shimizu T, Miura S, Kanai T.
Redox-dependent PPARγ/Tnpo1 complex formation enhances PPARγ nuclear localization and signaling.
Free Radic Biol Med
2020
PubMed ID: 32553752
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13095
Mai NNH, Yamaguchi Y, Choijookhuu N, Matsumoto J, Nanashima A, Takagi H, Sato K, Tuan LQ, Hishikawa Y.
Photodynamic Therapy Using a Novel Phosphorus Tetraphenylporphyrin Induces an Anticancer Effect via Bax/Bcl-xL-related Mitochondrial Apoptosis in Biliary Cancer Cells.
Acta Histochem Cytochem
2020
PubMed ID: 32873990
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13115
Urabe T, Yanase Y, Motoike S, Harada K, Hide I, Tanaka S, Tsutsumi YM, Kawamoto M, Sakai N.
Propofol induces the elevation of intracellular calcium via morphological changes in intracellular organelles, including the endoplasmic reticulum and mitochondria.
Eur J Pharmacol
2020
PubMed ID: 32681942
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13163
Furuno K, Wang J, Suzuki K, Nakahata M, Sakai S.
Gelatin-Based Electrospun Fibers Insolubilized by Horseradish Peroxidase-Catalyzed Cross-Linking for Biomedical Applications.
ACS Omega
2020
PubMed ID: 32875262
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13193
Iio A, Kaji K, Kaji N, Hori M, Yonezawa T, Momoi Y, Maeda S.
Expression analysis of protease-activated receptor-2 in cats.
Vet Immunol Immunopathol
2020
PubMed ID: 32932190
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13200
Ago Y, Otsuka H, Sasai H, Abdelkreem E, Nakama M, Aoyama Y, Matsumoto H, Fujiki R, Ohara O, Akiyama K, Fukui K, Watanabe Y, Nakajima Y, Ohnishi H, Ito T, Fukao T.
Japanese patients with mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase deficiency: In vitro functional analysis of five novel HMGCS2 mutations.
Exp Ther Med
2020
PubMed ID: 32952630
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13307
Yanaizu M, Washizu C, Nukina N, Satoh JI, Kino Y.
CELF2 regulates the species-specific alternative splicing of TREM2.
Sci Rep
2020
PubMed ID: 33093587
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13349
Konishi H, Hayashi M, Taniguchi K, Nakamura M, Kuranaga Y, Ito Y, Kondo Y, Sasaki H, Terai Y, Akao Y, Ohmichi M.
The therapeutic potential of exosomal miR-22 for cervical cancer radiotherapy.
Cancer Biol Ther
2020
PubMed ID: 33190594
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13584
Uda RM, Yoshida N, Iwasaki T, Hayashi K.
pH-triggered solubility and cytotoxicity changes of malachite green derivatives incorporated in liposomes for killing cancer cells
J Mater Chem B
2020
8(36):8242-8248
PubMed ID: 32794526
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13610
Puteri MU, Watanabe Y, Wardhani BWK, Amalia R, Abdelaziz M, Kato M.
PMEPA1/TMEPAI isoforms function via its PY and Smad-interaction motifs for tumorigenic activities of breast cancer cells
Genes Cells
2020
25(6):375-390
PubMed ID: 32181976
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13620
Otagiri S, Ohnishi S, Ohara M, Fu Q, Yamamoto K, Yamamoto K, Katsurada T, Sakamoto N.
Oleoylethanolamide Ameliorates Dextran Sulfate Sodium-Induced Colitis in Rats
Front Pharmacol
2020
11:1277
PubMed ID: 32922296
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13944
Akaike Y, Chibazakura T.
Aberrant activation of cyclin A-CDK induces G2/M-phase checkpoint in human cells
Cell Cycle
2020
19(1):84-96
PubMed ID: 31760882
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14836
Punzalan LL, Jiang L, Mao D, Mahapatra AD, Sato S, Takemoto Y, Tsujimura M, Kusamori K, Nishikawa M, Zhou L, Uesugi M.
Chemoproteomic Profiling of a Pharmacophore-Focused Chemical Library
Cell Chem Biol
2020
27(6):708-718.e1
PubMed ID: 32402240
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11179
Ali F, Hossain MS, Sejimo S, Akashi K.
Plasmalogens Inhibit Endocytosis of Toll-like Receptor 4 to Attenuate the Inflammatory Signal in Microglial Cells.
Mol. Neurobiol.
2019
56(5):3404-3419
PubMed ID: 30128650
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4052
Kidoya H, Muramatsu F, Shimamura T, Jia W, Satoh T, Hayashi Y, Naito H, Kunisaki Y, Arai F, Seki M, Suzuki Y, Osawa T, Akira S, Takakura N.
Regnase-1-mediated post-transcriptional regulation is essential for hematopoietic stem and progenitor cell homeostasis
Nat Commun
2019
10:1072
PubMed ID: 30842549
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11312
Manabe A, Furukawa C, Hasegawa H, Matsunaga T, Endo S, Ikari A.
Upregulation of transient receptor potential melastatin 6 channel expression by rosiglitazone and all-trans-retinoic acid in erlotinib-treated renal tubular epithelial cells.
J. Cell. Physiol.
2019
PubMed ID: 30461012
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11394
Hayashi M, Nakashima T, Yoshimura N, Okamoto K, Tanaka S, Takayanagi H.
Autoregulation of Osteocyte Sema3A Orchestrates Estrogen Action and Counteracts Bone Aging.
Cell Metab.
2019
PubMed ID: 30661929
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11402
Morita M, Hashimoto O.
Identification and expression of the medaka inhibin βE subunit.
Mol. Biol. Rep.
2019
PubMed ID: 30680594
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11412
Zhang W, Matsuo R, Takahara T, Shibata H, Maki M.
High Sensitive Quantitative Binding Assays Using a Nanoluciferase-Fused Probe for Analysis of ALG-2-Interacting Proteins.
Methods Mol. Biol.
2019
PubMed ID: 30710293
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11411
Zhang W, Takahara T, Achiha T, Shibata H, Maki M.
Cellular Ca2+-Responding Nanoluciferase Reporter Gene System Directed by Tandemly Repeated Pseudo-palindromic NFAT-Response Elements.
Methods Mol. Biol.
2019
PubMed ID: 30710269
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6050
Yokota S, Kuramochi H, Okubo K, Iwaya A, Tsuchiya S, Ichiki T.
Extracellular vesicles nanoarray technology: Immobilization of individual extracellular vesicles on nanopatterned polyethylene glycol-lipid conjugate brushes.
PLoS One
2019
14(10):e0224091
PubMed ID: 31648253
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11580
Tanaka J, Mabuchi Y, Hata K, Yasuhara R, Takamatsu K, Kujiraoka S, Yukimori A, Takakura I, Sumimoto H, Fukada T, Azuma M, Akiyama H, Nishimura R, Shimane T, Mishima K.
Sox9 regulates the luminal stem/progenitor cell properties of salivary glands.
Exp. Cell Res.
2019
PubMed ID: 31153924
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11586
Ikeda Y, Morita SY, Hatano R, Tsuji T, Terada T.
Enhancing effect of taurohyodeoxycholate on ABCB4-mediated phospholipid efflux.
Biochim Biophys Acta Mol Cell Biol Lipids
2019
PubMed ID: 31176036
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11628
Mitsui E, Yoshida S, Shinoda Y, Matsumori Y, Tsujii H, Tsuchida M, Wada S, Hasegawa M, Ito A, Mino K, Onuki T, Yoshida M, Sasaki R, Mizukami T.
Identification of ryuvidine as a KDM5A inhibitor.
Sci Rep
2019
PubMed ID: 31289306
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11800
Koizumi A, Narita S, Nakanishi H, Ishikawa M, Eguchi S, Kimura H, Takasuga S, Huang M, Inoue T, Sasaki J, Yoshioka T, Habuchi T, Sasaki T.
Increased fatty acyl saturation of phosphatidylinositol phosphates in prostate cancer progression.
Sci Rep
2019
PubMed ID: 31520002
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11867
Ginting TE, Christian S, Larasati YO, Suryatenggara J, Suriapranata IM, Mathew G.
Antiviral interferons induced by Newcastle disease virus (NDV) drive a tumor-selective apoptosis.
Sci Rep
2019
PubMed ID: 31641164
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6899
Miyano K, Shiraishi S, Minami, Sudo Y, Suzuki M, Yokoyama T, Terawaki K, Nonaka M, Murata H, Higami Y, Uezono Y.
Carboplatin Enhances the Activity of Human Transient Receptor Potential Ankyrin 1 through the Cyclic AMP-Protein Kinase A-A-Kinase Anchoring Protein (AKAP) Pathways.
Int J Mol Sci
2019
20(13):3271
PubMed ID: 31277262
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6937
Ryo Muko et al
Cloning and Detection of Equine Histidine-Rich Glycoprotein
Journal of Equine Veterinary Science
2019
73:121-126
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9810
Junko Shibato, Fumiko Takenoya, Takahiro Hirabayashi, Ai Kimura, Yusuke Iwasaki, Yoko Toyoda, Motohide Hori, Shigeru Tamogami, Randeep Rakwal, Seiji Shioda
Towards Identification of Bioactive Compounds in Cold Vacuum Extracted Double Cherry Blossom (Gosen-Sakura) Leaves
Plant Signal Behav
2019
14(10):e1644594
PubMed ID: 31342859
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10396
Takahiro Toda, Shinichiro Yamamoto, Noriko Umehara, Yasuo Mori, Minoru Wakamori, Shunichi Shimizu
Protective Effects of Duloxetine Against Cerebral Ischemia-Reperfusion Injury via Transient Receptor Potential Melastatin 2 Inhibition
J Pharmacol Exp Ther
2019
368(2):246-254
PubMed ID: 30523061
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10397
Murat Kutluay, Makoto Inoue and Iclal Saracoglu
Assessment of LXRα agonist activity and selective antiproliferative efficacy: a study on different parts of Digitalis species
Turkish Journal of Biochemistry
2019
44
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10400
Shun Adachi
Induction of hierarchy and time through one-dimensional probability space with certain topologies
bioRxiv
2019
September 24
|
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12328
Ikeda T, Ichikawa K, Shigeto H, Ishida T, Hirota R, Funabashi H, Kuroda A.
Arginine-mediated dissociation of single cells and cell sheets from a polystyrene culture dish
Biosci Biotechnol Biochem
2019
83(12):2272-2275
PubMed ID: 31482750
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12353
Li J, Yoshida Y, Kurita M, Usuki T.
Cynaropicrin and inhibition of NF-κB activation: A structure activity relationship study
Bioorg Med Chem Lett
2019
29(12):1518-1521
PubMed ID: 30987894
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12359
Nakai S, Uchitomi R, Matsuda R, Onishi T, Hatazawa Y, Kamei Y.
Screening dataset of food components that enhance transcriptional activity of PGC1-beta
Data Brief
2019
23:103814
PubMed ID: 31372459
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12361
Fujita S, Hirota T, Sakiyama R, Baba M, Ieiri I.
Identification of drug transporters contributing to oxaliplatin-induced peripheral neuropathy
J Neurochem
2019
148(3):373-385
PubMed ID: 30295925
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7018
Uchida S, Yoshinaga N, Yanagihara K, Yuba E, Kataoka K, Itaka K.
Designing immunostimulatory double stranded messenger RNA with maintained translational activity through hybridization with poly A sequences for effective vaccination.
Biomaterials
2018
150:162-170
PubMed ID: 29031816
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9502
Morita M, Sato T, Nomura M, Sakamoto Y, Inoue Y, Tanaka R, Ito S, Kurosawa K, Yamaguchi K, Sugiura Y, Takizaki H, Yamashita Y, Katakura R, Sato I, Kawai M, Okada Y, Watanabe H, Kondoh G, Matsumoto S, Kishimoto A, Obata M, Matsumoto M, Fukuhara T, Motohashi H, Suematsu M, Komatsu M, Nakayama KI, Watanabe T, Soga T, Shima H, Maemondo M, Tanuma N.
PKM1 Confers Metabolic Advantages and Promotes Cell-Autonomous Tumor Cell Growth.
Cancer Cell
2018
33:355-367.e7
PubMed ID: 29533781
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10620
Nakamura M, Fujita K, Toyoda Y, Takada T, Hasegawa H, Ichida K.
Investigation of the transport of xanthine dehydrogenase inhibitors by the urate transporter ABCG2.
Drug Metab. Pharmacokinet.
2018
33:77-81
PubMed ID: 29342419
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11076
Toyama K, Nomura W, Kobayakawa T, Tamamura H.
Delivery of a Proapoptotic Peptide to EGFR-Positive Cancer Cells by a Cyclic Peptide Mimicking the Dimerization Arm Structure of EGFR.
Bioconjug. Chem.
2018
29(6):2050-2057
PubMed ID: 29763296
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11083
Tsuchiya M, Hara Y, Okuda M, Itoh K, Nishioka R, Shiomi A, Nagao K, Mori M, Mori Y, Ikenouchi J, Suzuki R, Tanaka M, Ohwada T, Aoki J, Kanagawa M, Toda T, Nagata Y, Matsuda R, Takayama Y, Tominaga M, Umeda M.
Cell surface flip-flop of phosphatidylserine is critical for PIEZO1-mediated myotube formation.
Nat Commun
2018
9(1):2049
PubMed ID: 29799007
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11158
Matsumoto S, Caliskan N, Rodnina MV, Murata A, Nakatani K.
Small synthetic molecule-stabilized RNA pseudoknot as an activator for -1 ribosomal frameshifting.
Nucleic Acids Res.
2018
46(16):8079-8089
PubMed ID: 30085309
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11074
Tsukamoto H, Takeuchi S, Kubota K, Kobayashi Y, Kozakai S, Ukai I, Shichiku A, Okubo M, Numasaki M, Kanemitsu Y, Matsumoto Y, Nochi T, Watanabe K, Aso H, Tomioka Y.
Lipopolysaccharide (LPS)-binding protein stimulates CD14-dependent Toll-like receptor 4 internalization and LPS-induced TBK1-IKK?-IRF3 axis activation.
J. Biol. Chem.
2018
293(26):10186-10201
PubMed ID: 29760187
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11164
Mogi K, Hayashida K, Yamamoto T.
Damage-less Handling of Exosomes Using an Ion-depletion Zone in a Microchannel.
Anal Sci
2018
34(8):875-880
PubMed ID: 30101880
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11260
Fujita D, Arai T, Komori H, Shirasaki Y, Wakayama T, Nakanishi T, Tamai I.
Apple-Derived Nanoparticles Modulate Expression of Organic-Anion-Transporting Polypeptide (OATP) 2B1 in Caco-2 Cells.
Mol. Pharm.
2018
PubMed ID: 30359033
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11268
Hashimoto O, Funaba M, Sekiyama K, Doi S, Shindo D, Satoh R, Itoi H, Oiwa H, Morita M, Suzuki C, Sugiyama M, Yamakawa N, Takada H, Matsumura S, Inoue K, Oyadomari S, Sugino H, Kurisaki A.
Activin E Controls Energy Homeostasis in Both Brown and White Adipose Tissues as a Hepatokine.
Cell Rep
2018
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J Steroid Biochem Mol Biol
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Identification of a p53 target, CD137L, that mediates growth suppression and immune response of osteosarcoma cells
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Immunogenetics
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Epirubicin, Identified Using a Novel Luciferase Reporter Assay for Foxp3 Inhibitors, Inhibits Regulatory T Cell Activity.
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Int J Mol Med
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Mechanisms underlying the toxic effects of antimony species in human embryonic kidney cells (HEK-293) and their comparison with arsenic species
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Positive Allosteric Modulation of the Calcium-sensing Receptor by Physiological Concentrations of Glucose
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Development of a highly reproducible system to evaluate inhibition of cytochrome P450 3A4 activity by natural medicines.
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Efficacy of Recombinant Canine Distemper Virus Expressing Leishmania Antigen against Leishmania Challenge in Dogs.
PLoS Negl Trop Dis
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Bruton's tyrosine kinase is essential for NLRP3 inflammasome activation and contributes to ischaemic brain injury.
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Development of Rous sarcoma Virus-like Particles Displaying hCC49 scFv for Specific Targeted Drug Delivery to Human Colon Carcinoma Cells.
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Amyloidogenic lysozymes accumulate in the endoplasmic reticulum accompanied by the augmentation of ER stress signals.
Biochim. Biophys. Acta
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An improved superoxide-generating nanodevice for oxidative stress studies in cultured cells.
Biotechnology Reports
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Michiko Yoshida, Kenji Hata, Rikako Takashima, Koichiro Ono, Eriko Nakamura, Yoshifumi Takahata, Tomohiko Murakami, Sachiko Iseki, Teruko Takano-Yamamoto, Riko Nishimura, Toshiyuki Yoneda
The Transcription Factor Foxc1 Is Necessary for Ihh-Gli2-regulated Endochondral Ossification
Nat Commun
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Koichi Fujikawa, Ryo Fukumori, Saki Nakamura, Takaya Kutsukake, Takeshi Takarada, Yukio Yoneda
Potential Interactions of Calcium-Sensitive Reagents With Zinc Ion in Different Cultured Cells
PLoS One
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Efficient delivery to human lung fibroblasts (WI-38) of pirfenidone incorporated into liposomes modified with truncated basic fibroblast growth factor and its inhibitory effect on collagen synthesis in idiopathic pulmonary fibrosis.
Biol Pharm Bull
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Endo Y, Noguchi S, Hara Y, Hayashi YK, Motomura K, Miyatake S, Murakami N, Tanaka S, Yamashita S, Kizu R, Bamba M, Goto Y, Matsumoto N, Nonaka I, Nishino I.
Dominant mutations in ORAI1 cause tubular aggregate myopathy with hypocalcemia via constitutive activation of store-operated Ca²⁺ channels
Hum Mol Genet
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24(3):637-48
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Ohsawa Y, Takayama K, Nishimatsu S, Okada T, Fujino M, Fukai Y, Murakami T, Hagiwara H, Itoh F, Tsuchida K, Hayashi Y, Sunada Y.
The Inhibitory Core of the Myostatin Prodomain: Its Interaction with Both Type I and II Membrane Receptors, and Potential to Treat Muscle Atrophy
PLoS One
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Raster image cross-correlation analysis for spatiotemporal visualization of intracellular degradation activities against exogenous DNAs
Sci Rep
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Narita K, Sasamoto S, Koizumi S, Okazaki S, Nakamura H, Inoue T, Takeda S.
TRPV4 regulates the integrity of the blood-cerebrospinal fluid barrier and modulates transepithelial protein transport
FASEB J
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Involvement of an intracellular vesicular transport process in naked-sgRNA-mediated TRUE gene silencing
Mol Med Rep
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12(4):6365
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Yusuke Watarai, Michiyasu Ishizawa, Teikichi Ikura, Flavia C. M. Zacconi, Shigeyuki Uno, Nobutoshi Ito, Antonio Mouriño, Hiroaki Tokiwa, Makoto Makishima, Sachiko Yamada
Synthesis, Biological Activities, and X-ray Crystal Structural Analysis of 25-Hydroxy-25(or 26)-adamantyl-17-[20(22),23-diynyl]-21-norvitamin D Compounds
Journal of Medicinal Chemistry
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Xu H, Shen Z, Xiao J, Yang Y, Huang W, Zhou Z, Shen J, Zhu Y1, Liu XY, Chu L.
Acetylcholinesterase overexpression mediated by oncolytic adenovirus exhibited potent anti-tumor effect.
BMC Cancer
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Shimizu S, Yonezawa R, Hagiwara T, Yoshida T, Takahashi N, Hamano S, Negoro T, Toda T, Wakamori M, Mori Y, Ishii M.
Inhibitory effects of AG490 on H2O2-induced TRPM2-mediated Ca(2+) entry.
Eur J Pharmacol
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742:22-30
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Mutsuyo Takayama-Ito, Kazuo Nakamichi, Hitomi Kinoshita, Satsuki Kakiuchi, Ichiro Kurane, Masayuki Saijo, Chang-Kweng Lim
A Sensitive in Vitro Assay for the Detection of Residual Viable Rabies Virus in Inactivated Rabies Vaccines
Biologicals
2014
42 (1), 42-7
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Kazuhiro Shiozaki, Sena Ryuzono, Naoto Matsushita, Asami Ikeda, Kazuki Takeshita, Petros Kingstone Chigwechokha, Masaharu Komatsu, Taeko Miyagi
Molecular Cloning and Biochemical Characterization of Medaka (Oryzias Latipes) Lysosomal neu4 Sialidase
Fish Physiol Biochemc
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40(5):1461-72
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Petros Kingstone Chigwechokha, Masaharu Komatsu, Takao Itakura, Kazuhiro Shiozaki
Nile Tilapia Neu3 Sialidases: Molecular Cloning, Functional Characterization and Expression in Oreochromis Niloticus
Gene
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Inoue M, Tanabe H, Nakashima K, Ishida Y, Kotani H.
Rexinoids isolated from Sophora tonkinensis with a gene expression profile distinct from the synthetic rexinoid bexarotene
J Nat Prod
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Identification and characterization of cryptochrome4 in the ovary of western clawed frog Xenopus tropicalis
Zoolog Sci
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Wang H, Cai Z, Yang F, Luo J, Satoh M, Arai Y, Li D.
Enhanced antitumor efficacy of integrin-targeted oncolytic adenovirus AxdAdB3-F/RGD on bladder cancer
Urology
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Impact of Gender in Renal Cell Carcinoma: The Relationship of FABP7 and BRN2 Expression with Overall Survival
Clin Med Insights Oncol
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Zhou B, Wei FY, Kanai N, Fujimura A, Kaitsuka T, Tomizawa K.
Identification of a splicing variant that regulates type 2 diabetes risk factor CDKAL1 level by a coding-independent mechanism in human.
Hum Mol Genet
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Shiozaki K, Takeshita K, Ikeda M, Ikeda A, Harasaki Y, Komatsu M, Yamada S, Yamaguchi K, Miyagi T.
Molecular cloning and biochemical characterization of two novel Neu3 sialidases, neu3a and neu3b, from medaka (Oryzias latipes).
Biochimie
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Yano F, Saito T, Ogata N, Yamazawa T, Iino M, Chung UI, Kawaguchi H.
β-catenin regulates parathyroid hormone/parathyroid hormone-related protein receptor signals and chondrocyte hypertrophy through binding to the intracellular C-terminal region of the receptor.
Arthritis Rheum
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Syed Ahmed, Jinhua Dong, Megumi Yui, Tatsuya Kato, Jaebeom Lee, Enoch Y Park
Quantum Dots Incorporated Magnetic Nanoparticles for Imaging Colon Carcinoma Cells
J Nanobiotechnology
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