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Cell No. : Cell Name
RCB1433 : TEN  update : 2022/04/02
CommentHuman cell line derived from endometrial cancer. Clear cell carcinoma. Said c-erb-2(+), cathepsin D(+), CA125(+) in a part of cells.
Comment from the depositor
Terms and conditionsThere is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC.
Remarks
Order Form Order Form(C-0005.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)  
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
Basic information Depositor Izumi, Rikuichi
Originator Fushiki, Hiroshi
Year of deposit 1998
Animal human < Mammals
Genus Homo
Species sapiens
Race Japanese
Gender Female
Age at sampling 74 years
Tissue endometrium
Disease name Endometrial cancer
Metastastatic ability Yes
Classification cancer
Year of origin 1993
Lifespan infinite
Morphology epithelial-like
Cellosaurus(Expasy) CVCL_E063
deposit info
lot info
Medium Medium List
Culture type Adherent cells
Medium and additives MEM + 10% FBS
Antibiotics Free
Passage method 0.25% Trypsin
Culture information Passage ratio 1 : 4-8 split
SC frequency Subculture : once/week, Medium Renewal : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
Isozyme LD, NP
Chromosome mode 72-79(50) : 72(2), 73(6), 74(14), 75(12), 76(10)/
STR(human) OK
Images
deposit info
lot info
Reference information Reference 1
User's Publication 2


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Reference
2383  Fushiki H, Hidaka T, Fujimura M, Yasoshima K, Yamakawa Y, Izumi R  Characterization of a newly established human tumor cell line (TEN) from a patient with clear cell carcinoma of the uterine body and its sensitivity to anti-cancer agents.  Hum Cell  1997  10:199-208  PubMed ID: 9436040  

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User's Publication
4359  Kogata Y, Tanaka T, Ono YJ, Hayashi M, Terai Y, Ohmichi M.  Foretinib (GSK1363089) induces p53-dependent apoptosis in endometrial cancer.  Oncotarget  2018  9(32):22769-22784  PubMed ID: 29854314   DOI: 10.18632/oncotarget.25232
14682  Tanaka T, Terai Y, Ashihara K, Fujiwara S, Tanaka Y, Sasaki H, Tsunetoh S, Ohmichi M.  The efficacy of the cyclin-dependent kinase 4/6 inhibitor in endometrial cancer  PLoS One  2017  12(5):e0177019  PubMed ID: 28472136   DOI: 10.1371/journal.pone.0177019



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