A human cell line derived from acute myeloid leukemia (AML). AML was originated from CMMoL. Possessing Philadelphia chromosome and t(3;3)(q21;q26). Expressing EVI1 and BCR/ABL. Application consideration
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Hamaguchi H, Suzukawa K, Nagata K, Yamamoto K, Yagasaki F, Morishita K
Establishment of a novel human myeloid leukaemia cell line (HNT-34) with t(3;3)(q21;q26), t(9;22)(q34;q11) and the expression of EVI1 gene, P210 and P190 BCR/ABL chimaeric transcripts from a patient with AML after MDS with 3q21q26 syndrome.Br J Haematol
PubMed ID: 9266939
Norio Yamakawa, Kazuko Kaneda, Yusuke Saito, Emi Ichihara, Kazuhiro Morishita
The Increased Expression of Integrin α6 (ITGA6) Enhances Drug Resistance in EVI1(high) LeukemiaPLoS One
PubMed ID: 22295105
Saito Y, Nakahata S, Yamakawa N, Kaneda K, Ichihara E, Suekane A, Morishita K.
CD52 as a molecular target for immunotherapy to treat acute myeloid leukemia with high EVI1 expression.Leukemia
PubMed ID: 21394097