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Cell No. : Cell Name
RCB1283 : B16 melanoma  update : 2024/05/13
CommentMouse melanoma producing melanin. Application consideration
Comment from the depositor
Terms and conditionsThere is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC.
Remarks
Order Form Order Form(C-0005.pdf)   MTA(C-0007.pdf)   MTA(C-0007p.pdf)  
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
Basic information Depositor Hamada, Hirofumi
Year of deposit 1996
Another name B16/parent
Animal _mouse < Mammals
Strain name C57BL/6
Tissue skin
Disease name melanoma
Classification cancer
Lifespan infinite
Morphology epithelial-like
Cellosaurus(Expasy) CVCL_F936
deposit info
lot info
Medium Medium List
Culture type Adherent cells
Culture medium DMEM (low glucose) + 10% FBS
Antibiotics Free
Passage method 0.25% Trypsin
Culture information Passage ratio 1 : 8 split
SC frequency Subculture : 2 times/week
Temperature 37 ℃
CO2 concentration 5 %
Freeze medium Medium + 10% DMSO
Freezing method Slow freezing
Mycoplasma (-)
SSLP(mouse) OK
Isozyme LD, NP
Images
deposit info
lot info
Reference information Reference 4
User's Publication 72


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Reference
2131  Nakamura Y, Wakimoto H, Abe J, Kanegae Y, Saito I, Aoyagi M, Hirakawa K, Hamada H  Adoptive immunotherapy with murine tumor-specific T lymphocytes engineered to secrete interleukin 2.  Cancer Res  1994  54:5757-60  PubMed ID: 7525049  
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3488  HU F, LESNEY PF.  THE ISOLATION AND CYTOLOGY OF TWO PIGMENT CELL STRAINS FROM B-16 MOUSE MELANOMAS  Cancer Res  1964  24:1634-43.  PubMed ID: 14234007  
547  Riley,V.  Enzymatic determination of transmissible replicating factors associated with mouse tumors.  Ann N Y Acad Sci  1963  100:762-790  PubMed ID: 13973915  

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User's Publication
19811  Une S, Nakata R, Nonaka K, Akiyama J.  Antiproliferative and anti-inflammatory effects of fractionated crude lectins from boiled kidney beans (Phaseolus vulgaris)  J Food Sci  2024  89(1):671-683  PubMed ID: 37983860   DOI: 10.1111/1750-3841.16847
21542  Morihiro K, Morita S, Harada N, Baba M, Yum J, Naito M, Miyata K, Nagae G, Okamoto A.  RNA Oncological Therapeutics: Intracellular Hairpin RNA Assembly Enables MicroRNA-Triggered Anticancer Functionality.  J Am Chem Soc  2024    PubMed ID: 38170469   DOI: 10.1021/jacs.3c09524
21636  Srirat T, Hayakawa T, Mise-Omata S, Nakagawara K, Ando M, Shichino S, Ito M, Yoshimura A.  NR4a1/2 deletion promotes accumulation of TCF1+ stem-like precursors of exhausted CD8+ T cells in the tumor microenvironment.  Cell Rep  2024  43(3):113898  PubMed ID: 38451819   DOI: 10.1016/j.celrep.2024.113898
21978  Hayashi Y, Kamimura-Aoyagi Y, Nishikawa S, Noka R, Iwata R, Iwabuchi A, Watanabe Y, Matsunuma N, Yuki K, Kobayashi H, Harada Y, Harada H.  IL36G-producing neutrophil-like monocytes promote cachexia in cancer.  Nat Commun  2024  15(1):7662  PubMed ID: 39266531   DOI: 10.1038/s41467-024-51873-x
17701  Tokudome Y, Fukutomi M.  Sphingomyelin reduces melanogenesis in murine B16 melanoma cells through indirect suppression of tyrosinase  Cytotechnology  2023  75(2):93-101  PubMed ID: 36969571   DOI: 10.1007/s10616-022-00562-y
21045  Hirata T, Harada Y, Hirosawa KM, Tokoro Y, Suzuki KGN, Kizuka Y.  N-acetylglucosaminyltransferase-V (GnT-V)-enriched small extracellular vesicles mediate N-glycan remodeling in recipient cells.  iScience  2023  26(1):105747  PubMed ID: 36590176   DOI: 10.1016/j.isci.2022.105747
21065  Morihiro K, Osumi H, Morita S, Hattori T, Baba M, Harada N, Ohashi R, Okamoto A.  Oncolytic Hairpin DNA Pair: Selective Cytotoxic Inducer through MicroRNA-Triggered DNA Self-Assembly.  J Am Chem Soc  2023  145(1):135-142  PubMed ID: 36538570   DOI: 10.1021/jacs.2c08974
21308  Toyofuku K, Wakabayashi R, Kamiya N, Goto M.  Non-Invasive Transdermal Delivery of Antisense Oligonucleotides with Biocompatible Ionic Liquids.  ACS Appl Mater Interfaces  2023    PubMed ID: 37405761   DOI: 10.1021/acsami.3c03900
21352  Mise-Omata S, Ando M, Srirat T, Nakagawara K, Hayakawa T, Iizuka-Koga M, Nishimasu H, Nureki O, Ito M, Yoshimura A.  SOCS3 deletion in effector T cells confers an anti-tumorigenic role of IL-6 to the pro-tumorigenic cytokine.  Cell Rep  2023  112940  PubMed ID: 37582370   DOI: 10.1016/j.celrep.2023.112940
20556  Watanabe S, Yuba E, Akazawa T, Wijewardana V, Kakihara Y, Azuma A, Hagimori K, Kanegi R, Hatoya S, Inoue N, Inaba T, Sugiura K.  Potent adjuvant effect elicited for tumor immunotherapy by a liposome conjugated pH-sensitive polymer and dendritic cell-targeting Toll-like-receptor ligand.  Vaccine  2022    PubMed ID: 35131134   DOI: 10.1016/j.vaccine.2022.01.048
20835  Mizuta K, Matsubara T, Goto A, Addison WN, Nakatomi M, Matsuo K, Tada-Shigeyama Y, Yaginuma T, Honda H, Yoshioka I, Kokabu S.  Plectin promotes tumor formation by B16 mouse melanoma cells via regulation of Rous sarcoma oncogene activity.  BMC Cancer  2022  22(1):936  PubMed ID: 36038818   DOI: 10.1186/s12885-022-10033-4
21001  Okada T, Iwayama T, Ogura T, Murakami S, Ogura T.  Structural analysis of melanosomes in living mammalian cells using scanning electron-assisted dielectric microscopy with deep neural network.  Comput Struct Biotechnol J  2022  21:506-518  PubMed ID: 36618988   DOI: 10.1016/j.csbj.2022.12.027
20012  Bourhim T, Villareal MO, Couderc F, Hafidi A, Isoda H, Gadhi C.  Melanogenesis Promoting Effect, Antioxidant Activity, and UPLC-ESI-HRMS Characterization of Phenolic Compounds of Argan Leaves Extract.  Molecules  2021  26(2)  PubMed ID: 33445748   DOI: 10.3390/molecules26020371
20199  Tomita T, Kato M, Mishima T, Matsunaga Y, Sanjo H, Ito KI, Minagawa K, Matsui T, Oikawa H, Takahashi S, Takao T, Iwai N, Mino T, Takeuchi O, Maru Y, Hiratsuka S.  Extracellular mRNA transported to the nucleus exerts translation-independent function.  Nat Commun  2021  12(1):3655  PubMed ID: 34135341   DOI: 10.1038/s41467-021-23969-1
12157  Enos Tangke Arung, Syafrizal , Whicliffe Fiernaleonardo Pasedan, Nataniel Tandirogang, Sukemi , Ahmed E. Allam, Yhiya Amen, Kuniyoshi Shimizu, Hiroya Ishikawa  Prenylated Flavonoids as Antioxidant and Melanin Inhibitors From Stingless Bee (Wallacetrigona incisa) Propolis  SAGE Journals  2020      DOI: 10.1177/1934578X20911272
12169  Teerapat Rodboon, Sarawoot Palipoch, Seiji Okada, Nisamanee Charoenchon, Yaowarin Nakornpakdee, Prasit Suwannalert  Oxyresveratrol inhibits cellular tyrosinase-related oxidative stress-induced melanogenesis in B16 melanoma cells  Journal of Applied Phamaceutical Science  2020      DOI: 10.7324/JAPS.2020.104002
13123  Ikarashi N, Fukuda N, Ochiai M, Sasaki M, Kon R, Sakai H, Hatanaka M, Kamei J.  Lactobacillus helveticus-Fermented Milk Whey Suppresses Melanin Production by Inhibiting Tyrosinase through Decreasing MITF Expression.  Nutrients  2020    PubMed ID: 32674403   DOI: 10.3390/nu12072082
13128  Bito T, Koseki K, Asano R, Ueda N, Yamada T, Yabuta Y, Ichiyanagi T, Ishihara A, Watanabe K, Watanabe F.  5-hydroxymethyl-2-furaldehyde purified from Japanese pear (Pyrus pyrifolia Nakai cv. Nijisseiki) juice concentrate inhibits melanogenesis in B16 mouse melanoma cells.  Biosci Biotechnol Biochem  2020    PubMed ID: 32674671   DOI: 10.1080/09168451.2020.1792762
13286  Harada Y, Nakajima K, Suzuki T, Fukushige T, Kondo K, Seino J, Ohkawa Y, Suzuki T, Inoue H, Kanekura T, Dohmae N, Taniguchi N, Maruyama I.  Glycometabolic Regulation of the Biogenesis of Small Extracellular Vesicles.  Cell Rep  2020    PubMed ID: 33053347   DOI: 10.1016/j.celrep.2020.108261
13292  Panichakul T, Rodboon T, Suwannalert P, Tripetch C, Rungruang R, Boohuad N, Youdee P.  Additive Effect of a Combination of Artocarpus lakoocha and Glycyrrhiza glabra Extracts on Tyrosinase Inhibition in Melanoma B16 Cells.  Pharmaceuticals (Basel)  2020    PubMed ID: 33066628   DOI: 10.3390/ph13100310
13430  Yoshihiro Tokudome , Tsuyoshi Hoshi ,Sayaka Mori, Ichiro Hijikuro  Synthesis of Resorcinol Derivatives and their Effects on Melanin Production  Cosmetics  2020      DOI: 10.3390/cosmetics7030055
13494  Ukiya M, Sato D, Kimura H, Hirai Y, Nishina A.  Tokoronin Contained in Dioscorea tokoro Makino ex Miyabe Suppressed α-MSH-Induced Melanogenesis in B16 Cells via Suppression of Classical MAPK Pathway Activation  Chem Biodivers  2020  17(6):e2000077  PubMed ID: 32378303   DOI: 10.1002/cbdv.202000077
11683  Enos T. Arung, Jhonner R. Sinamabela, Enih Rosamah, Irawan W. Kusuma, Harlinda Kuspradini, Ahmed E. Alam, Yhiya Amen, Hiroyuki Tanaka, Dedi Satria, Kuniyoshi Shimizu, Hiroya Ishikawa  Antioxidant and Antimelanogenesis Activities of Glyasperin A From Macaranga pruinosa Leaves  Natural Product Communications  2019      DOI: 10.1177/1934578X19867192
6893  Ogawa M, Yaginuma T, Nakatomi C, Nakajima T, Tada-Shigeyama Y, Addison WN, Urata M, Matsubara T, Watanabe K, Matsuo K, Sato T, Honda H, Hikiji H, Watanabe S, Kokabu S.  Transducin-like enhancer of split 3 regulates proliferation of melanoma cells via histone deacetylase activity.  Oncotarget  2019  10(3):404-414  PubMed ID: 30719233   DOI: 10.18632/oncotarget.26552
18097  Ushigusa T, Koyama Y, Ito T, Watanabe K, Chambers JK, Hasegawa A, Uchida K, Kanegi R, Hatoya S, Inaba T, Sugiura K.  Innate immunity mediated by dendritic cells/macrophages plays a central role in the early period in tumor treatment using gene of Mycobacterium tuberculosis antigen  J Vet Med Sci  2018  80(2):190-196  PubMed ID: 29311492   DOI: 10.1292/jvms.17-0466
10646  Fujimaki T, Mori S, Horikawa M, Fukui Y.  Isolation of proanthocyanidins from red wine, and their inhibitory effects on melanin synthesis in vitro.  Food Chem  2018  248:61-69  PubMed ID: 29329871   DOI: 10.1016/j.foodchem.2017.12.024
10698  Zhu WJ, Kobayashi M, Yamada K, Nishi K, Takahashi K, Mizutani A, Nishii R, Flores LG, Shikano N, Kunishima M, Kawai K.  Development of radioiodine labeled acetaminophen for specific, high-contrast imaging of malignant melanoma.  Nucl. Med. Biol.  2018  59:16-21  PubMed ID: 29413752   DOI: 10.1016/j.nucmedbio.2017.12.008
11043    Effect of melanogenesis inhibition by a yeast extract in comparison to that by other food extracts, and its mechanism of action  Journal of Food Biochemistry  2018  42, e12520    DOI: 10.1111/jfbc.12520
4065    Bioactive isoquinoline alkaloids from Glaucium arabicum  Phytochemistry Letters  2018  8:139-144    DOI: 10.1016/j.phytol.2018.10.004
4066  Tomohiro Bito, Kyohei Koseki, Tomohiro Moriguchi, Yu Sasaki, Yukinori Yabuta, Tsuyoshi Ichiyanagi, Fumio Watanabe  Cycloalliin Inhibits Melanin Biosynthesis in B16 Mouse Melanoma Cells  Food Science and Technology Research  2018  24:627-633    DOI: 10.3136/fstr.24.627
4073  Parichaya Aimvijarn, Teerapat Rodboon, Witchuda Payuhakrit, Prasit Suwannalert  Nymphaea pubescens Induces Apoptosis, Suppresses Cellular Oxidants-Related Cell Invasion in B16 Melanoma Cells  Pharmaceutical Sciences  2018  24, 199-206    DOI: 10.15171/PS.2018.29
4152  Nishina A, Miura A, Goto M, Terakado K, Sato D, Kimura H, Hirai Y, Sato H, Phay N.  Mansonone E from Mansonia gagei Inhibited α-MSH-Induced Melanogenesis in B16 Cells by Inhibiting CREB Expression and Phosphorylation in the PI3K/Akt Pathway.  Biol. Pharm. Bull.  2018    PubMed ID: 29709914   DOI: 10.1248/bpb.b17-01045
4153  Bourhim T, Villareal MO, Gadhi C, Hafidi A, Isoda H.  Depigmenting effect of argan press-cake extract through the down-regulation of Mitf and melanogenic enzymes expression in B16 murine melanoma cells.  Cytotechnology  2018    PubMed ID: 29946948   DOI: 10.1007/s10616-018-0232-6
4154  Ishihara A, Ide Y, Bito T, Ube N, Endo N, Sotome K, Maekawa N, Ueno K, Nakagiri A.  Novel tyrosinase inhibitors from liquid culture of Neolentinus lepideus.  Biosci. Biotechnol. Biochem.  2018    PubMed ID: 29297258   DOI: 10.1080/09168451.2017.1415125
4155  Semba T, Sugihara E, Kamoshita N, Ueno S, Fukuda K, Yoshino M, Takao K, Yoshikawa K, Izuhara K, Arima Y, Suzuki M, Saya H.  Periostin antisense oligonucleotide suppresses bleomycin-induced formation of a lung premetastatic niche for melanoma.  Cancer Sci.  2018    PubMed ID: 29498146   DOI: 10.1111/cas.13554
4155  Semba T, Sugihara E, Kamoshita N, Ueno S, Fukuda K, Yoshino M, Takao K, Yoshikawa K, Izuhara K, Arima Y, Suzuki M, Saya H.  Periostin antisense oligonucleotide suppresses bleomycin-induced formation of a lung premetastatic niche for melanoma.  Cancer Sci.  2018    PubMed ID: 29498146   DOI: 10.1111/cas.13554
4156  Hatano T, Yashiro M, Fujikawa H, Motomura H.  C-X-C Motif Ligand 1 (CXCL1) from melanoma cells down-regulates the invasion of their metastatic melanoma cells.  Oncotarget  2018    PubMed ID: 30123429   DOI: 10.18632/oncotarget.25783
4157  Aimvijarn P, Palipoch S, Okada S, Suwannalert P.  Thai Water Lily Extract Induces B16 Melanoma Cell Apoptosis and Inhibits Cellular Invasion Through the Role of Cellular Oxidants  Asian Pac. J. Cancer Prev.  2018    PubMed ID: 29373906   DOI: 10.22034/APJCP.2018.19.1.149
14538  Mayuko Hataia, Hisae Yoshitomia, Toshiaki Nishigakib, and Ming Gaoa  Efek Penghambatan Minyak Buah Merah Terhadap Melanogenesis Melalui Degradasi Tirosinase  Warta IHP/Journal of Agro-based Industry  2018  35:53-59   
10219  Kawata M, Taniguchi Y, Mori D, Yano F, Ohba S, Chung UI, Shimogori T, Mills AA, Tanaka S, Saito T.  Different regulation of limb development by p63 transcript variants.  PLoS ONE  2017  12:e0174122  PubMed ID: 28333962   DOI: 10.1371/journal.pone.0174122
12205  Amane Sutoh, Maria Carmelita Z.Kasuya Kenichi Hatanaka  Cellular glycosylation of amphiphilic saccharide primer in liquid/liquid interface culture system employing fluorous solvents  Journal of Fluorine Chemistry  2016  188:76-79    DOI: 10.1016/j.jfluchem.2016.06.011
12877  Goto Y, Yajima I, Kumasaka M, Ohgami N, Tanaka A, Tsuzuki T, Inoue Y, Fukushima S, Ihn H, Kyoya M, Ohashi H, Kawakami T, Bennett DC, Kato M.  Transcription factor LSF (TFCP2) inhibits melanoma growth  Oncotarget  2016  7(3):2379-90  PubMed ID: 26506241   DOI: 10.18632/oncotarget.6230
7522  ET Arung, W Suwinarti, M Hendra, S Supomo, IW Kusuma, DCN Puteri, HA Eroglu, Y Kim, K Shimizu, H Ishikawa  Determination of Antioxidant and Anti-Melanogenesis Activities of Indonesian Lai, Durio kutejensis [Bombacaceae (Hassk) Becc] Fruit Extract.  Tropical Journal of Pharmaceutical Research  2015  14:41-46    DOI: 10.4314/tjpr.v14i1.7
6339  Miyazaki J, Tsurui H, Kawasumi K, Kobayashi T.  Sensitivity enhancement of photothermal microscopy with radially segmented balanced detection.  Opt Lett  2015  40(4):479-82  PubMed ID: 25680129   DOI: 10.1364/OL.40.000479
6340  He J, Miyazaki J, Wang N, Tsurui H, Kobayashi T.  Label-free imaging of melanoma with nonlinear photothermal microscopy.  Opt Lett  2015  40(7):1141-4  PubMed ID: 25831277   DOI: 10.1364/OL.40.001141
6341  Miyazaki J, Tsurui H, Kawasumi K, Kobayashi T.  Simultaneous dual-wavelength imaging of nonfluorescent tissues with 3D subdiffraction photothermal microscopy.  Opt Express  2015  23(3):3647-56  PubMed ID: 25836217   DOI: 10.1364/OE.23.003647
6342  Hitoshi Kamauchi et al  New sesquiterpenoids isolated from Atractylodes lancea fermented by marine fungus  Tetrahedron  2015  71:1909-1914    DOI: 10.1016/j.tet.2015.02.041
15134  Hata R, Izukuri K, Kato Y, Sasaki S, Mukaida N, Maehata Y, Miyamoto C, Akasaka T, Yang X, Nagashima Y, Takeda K, Kiyono T, Taniguchi M.  Suppressed rate of carcinogenesis and decreases in tumour volume and lung metastasis in CXCL14/BRAK transgenic mice  Sci Rep  2015  5:9083  PubMed ID: 25765541   DOI: 10.1038/srep09083
15445  Erika Hayashi, Kaori Hachiya, Satoshi Kojo, Muhammad Baghdadi, Shintaro Takeuchi, Hiroyuki Yamanaka, Hirotak Abe, Haruka Wada, Ken-ichiro Seino  α-MSH stimulation contributes to TGF-β1 production via MC1R-MITF signaling pathway in melanoma cell  Inflammation and Regeneration  2015  35:244-254    DOI: 10.2492/inflammregen.35.244
15827  Yukinori Yabuta, Eri Hashimoto, Takashi Takeuchi, Setsuko Sakaki, Yuji Yamaguchi, Hiroyuki Takenaka, Fumio Watanabe  Characterization of a Hot Water Extract of an Edible Cyanobacterium Nostochopsis sp. for Use as an Ingredient in Cosmetics  Food Science and Technology Research  2014  20:505-507    DOI: 10.3136/fstr.20.505
16546  Tabuti JR, Hassen IE, Pateh UU, Mahomoodally MF.  Recent Advances towards Validating Efficacy and Safety of African Traditional Medicines  Evid Based Complement Alternat Med   2014  2014:260567  PubMed ID: 24527042   DOI: 10.1155/2014/260567
17141  Rie Wakabayashi, Ryutaro Ishiyama, Noriho Kamiya, Masahiro Goto  A novel surface-coated nanocarrier for efficient encapsulation and delivery of camptothecin to cells  MedChemComm  2014  5:1515-1519    DOI: 10.1039/c4md00179f
13653  Villareal MO, Han J, Ikuta K, Isoda H.  Mechanism of Mitf inhibition and morphological differentiation effects of hirsein A on B16 melanoma cells revealed by DNA microarray  J Dermatol Sci  2012  67(1):26-36.  PubMed ID: 22564683   DOI: 10.1016/j.jdermsci.2012.04.005
7888  Fujii T, Ikeda K, Saito M.  Inhibitory effect of rose hip (Rosa canina L.) on melanogenesis in mouse melanoma cells and on pigmentation in brown guinea pigs.  Biosci. Biotechnol. Biochem.  2011  75:489-95  PubMed ID: 21389613   DOI: 10.1271/bbb.100702
7963  Tamboli IY, Hampel H, Tien NT, Tolksdorf K, Breiden B, Mathews PM, Saftig P, Sandhoff K, Walter J.  Sphingolipid storage affects autophagic metabolism of the amyloid precursor protein and promotes Abeta generation.  J. Neurosci.  2011  31:1837-49  PubMed ID: 21289194   DOI: 10.1523/JNEUROSCI.2954-10.2011
16804  Sainz J, García-Alcalde F, Blanco A, Concha A.  Genome-wide gene expression analysis in mouse embryonic stem cells  Int J Dev Biol  2011  995-1006  PubMed ID: 22252498   DOI: 10.1387/ijdb.103123js
8326  Izukuri K, Suzuki K, Yajima N, Ozawa S, Ito S, Kubota E, Hata R.  Chemokine CXCL14/BRAK transgenic mice suppress growth of carcinoma cell transplants. [corrected]  Transgenic Res.  2010  19:1109-17  PubMed ID: 20333465   DOI: 10.1007/s11248-010-9384-7
8459  Obara M, Sakuma T, Fujikawa K.  The third type III module of human fibronectin mediates cell adhesion and migration.  J. Biochem.  2010  147:327-35  PubMed ID: 19880379   DOI: 10.1093/jb/mvp168
9082  Maria Carmelita Z Kasuya, Kenichi Hatanaka  Easy Production of a Glycolipid Analogue Using Animal Cells in Culture  Chem Biodivers  2010  7 (2), 440-6  PubMed ID: 20151390   DOI: 10.1002/cbdv.200900176
15699  Akihiro Michihara, Mai Shimatani, Sachiyo Morita, Kenji Akasaki  Reduction of Mevalonate Pyrophosphate Decarboxylase in Mouse Melanoma Cells Treated with δ-Tocotrienol Is Not Associated with Reduction of Cholesterol Content or Release of Lysosomes and Melanosomes  JOURNAL OF HEALTH SCIENCE  2010  56:355-360    DOI: 10.1248/jhs.56.355
8504  Yoshii Y, Waki A, Furukawa T, Kiyono Y, Mori T, Yoshii H, Kudo T, Okazawa H, Welch MJ, Fujibayashi Y.  Tumor uptake of radiolabeled acetate reflects the expression of cytosolic acetyl-CoA synthetase: implications for the mechanism of acetate PET.  Nucl. Med. Biol.  2009  36:771-7  PubMed ID: 19720289   DOI: 10.1016/j.nucmedbio.2009.05.006
8576  Yoshii Y, Furukawa T, Yoshii H, Mori T, Kiyono Y, Waki A, Kobayashi M, Tsujikawa T, Kudo T, Okazawa H, Yonekura Y, Fujibayashi Y.  Cytosolic acetyl-CoA synthetase affected tumor cell survival under hypoxia: the possible function in tumor acetyl-CoA/acetate metabolism.  Cancer Sci.  2009  100:821-7  PubMed ID: 19445015   DOI: 10.1111/j.1349-7006.2009.01099.x
15700  Akihiro Michihara, Sachiyo Morita, Yae Hirokawa, Saya Ago, Kenji Akasaki, Hiroshi Tsuji  Delta-Tocotrienol Causes Decrease of Melanin Content in Mouse Melanoma Cells  Journal of Health Science  2009  55:314-318    DOI: 10.1248/jhs.55.314
15643  Akihiro Michihara, Sachiyo Morita, Ken Toda, Kenji Akasaki, Hiroshi Tsuji  Mevalonate Pyrophosphate Decarboxylase is Predominantly Located in the Cytosol of both B16 and B16F10 Cells in Mouse Melanoma Treated with Lovastatin  Journal of Health Science  2008  54:216-223    DOI: 10.1248/jhs.54.216
19041  Aoki Y, Tanigawa T, Abe H, Fujiwara Y.  Melanogenesis inhibition by an oolong tea extract in b16 mouse melanoma cells and UV-induced skin pigmentation in brownish guinea pigs.  Biosci Biotechnol Biochem  2007  71:1879-85    DOI: 10.1271/bbb.70099
13658  Efdi M, Ohguchi K, Akao Y, Nozawa Y, Koketsu M, Ishihara H.  N-trans-feruloyltyramine as a melanin biosynthesis inhibitor  Biol Pharm Bull  2007  30(10):1972-4  PubMed ID: 17917275   DOI: 10.1248/bpb.30.1972
3410  Tamboli, Irfan Y, Prager, Kai, Barth, Esther, Heneka, Michael, Sandhoff, Konrad, Walter, Jochen  Inhibition of glycosphingolipid biosynthesis reduces secretion of the beta-amyloid precursor protein and amyloid beta-peptide.  J Biol Chem  2005  280:28110-7  PubMed ID: 15923191   DOI: 10.1074/jbc.M414525200
3595  Ohguchi K, Banno Y, Nakagawa Y, Akao Y, Nozawa Y.  Negative regulation of melanogenesis by phospholipase D1 through mTOR/p70 S6 kinase 1 signaling in mouse B16 melanoma cells.  J Cell Physiol  2005  205(3):444-51  PubMed ID: 15895362   DOI: 10.1002/jcp.20421
18749  Li X, Bukawa H, Hirota M, Tsuyuki Y, Omura S, Fujita K.  Novel OK-432-conjugated tumor vaccines induce tumor-specific immunity against murine tongue cancer  J Dent Res  2003  82(8):636-4  PubMed ID: 12885850   DOI: 10.1177/154405910308200813
18730  Ono K, Ishihara M, Ishikawa K, Ozeki Y, Deguchi H, Sato M, Hashimoto H, Saito Y, Yura H, Kurita A, Maehara T.  Periodate-treated, non-anticoagulant heparin-carrying polystyrene (NAC-HCPS) affects angiogenesis and inhibits subcutaneous induced tumour growth and metastasis to the lung  Br J Cancer  2002  86(11):1803-12  PubMed ID: 12087470   DOI: 10.1038/sj.bjc.6600307
5400  Kawaguchi N, Noda M.  Mitf is expressed in osteoclast progenitors in vitro.  Exp Cell Res  2000  260(2):284-91  PubMed ID: 11035923   DOI: 10.1006/excr.2000.5020
14427  Misawa E, Sakurai T, Yamada M, Hayasawa H, Motoyoshi K.  Effects of macrophage colony-stimulating factor and interleukin-2 administration on NK1.1(+) cells in mice  Int J Immunopharmacol  2000  22(11):967-77  PubMed ID: 11090705   DOI: 10.1016/s0192-0561(00)00061-8



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