Cell No. : Cell Name
RCB1279 : TtT/GF
update : 2022/08/18
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| Comment | Mouse cell line derived from pituitary tumor (thyrotropin-producing tumor). Pituitary folliculo-stellate-like cells. FGF-dependent cell line. GFAP positive. S-100 positive. Said producing IL-6. |
| Comment from the depositor | |
| Terms and conditions | There is no restriction regarding use for basic researches. In relation to commercial use and use for patent filing, first of all please contact the RIKEN BRC. |
| Remarks | |
| Order Form |
Order Form(C-0005.pdf)
MTA(C-0007.pdf)
MTA(C-0007p.pdf)
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|
Regarding MTA between user institutions and RIKEN BRC, there are two kinds of MTA, not-for-profit academic purpose (C-XXXX) and for-profit research purpose (C-XXXXp) , depending on the sort of user institutions and the purposes of use. Please use an appropriate MTA(to see). In relation to commercial use and use for patent filing, first of all Please contact RIKEN BRC (cellbank.brc@riken.jp).
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Basic information
|
Depositor |
Inoue, Kinji
|
| Originator |
Inoue, Kinji
|
| Year of deposit |
1996
|
| Animal |
_mouse
< Mammals
|
| Tissue |
pituitary
|
| Classification |
semi-normal
|
|
Lifespan |
infinite
|
| Morphology |
epithelial-like
|
| Cellosaurus(Expasy) |
CVCL_S512
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| |
deposit info |
lot info |
|
Medium |
Medium List |
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Culture type |
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Adherent cells
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| Culture medium |
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DMEM/HamF12 + 2.5% FBS + 10% HS (GIBCO)
|
| Antibiotics |
|
Free
|
|
Passage method |
|
0.25% Trypsin
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Culture information
|
Passage ratio |
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1 : 4 split
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| SC frequency |
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Subculture : once/week, Medium Renewal : 2 times/week
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| Temperature |
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37
℃
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| CO2 concentration |
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5
%
|
| Freeze medium |
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Medium + 10% DMSO
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| Freezing method |
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Slow freezing
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| Mycoplasma |
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(-)
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| SSLP(mouse) |
|
OK
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| Isozyme |
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LD, NP
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| Images |
deposit info | lot info |
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| Reference information |
Reference |
8
|
| User's Publication |
5
|
| Reference |
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3325
T Yamasaki, H Fujita, K Inoue, T Fujita, N Yamashita
Regulation of K+ channels by cell contact in a cloned folliculo-stellate cell (TtT/GF)
Endocrinology
1997
138(10):4346-50.
PubMed ID: 9322949
DOI: 10.1210/endo.138.10.5445
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3326
U Renner, J Gloddek, E Arzt, K Inoue, G K Stalla
Interleukin-6 is an autocrine growth factor for folliculostellate-like TtT/GF mouse pituitary tumor cells
Exp Clin Endocrinol Diabetes
1997
105(6):345-52
PubMed ID: 9439931
DOI: 10.1055/s-0029-1211777
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3328
H Kobayashi, J Fukata, N Murakami, T Usui, O Ebisui, S Muro, I Hanaoka, K Inoue, H Imura, K Nakao
Tumor necrosis factor receptors in the pituitary cells
Brain Res
1997
758(1-2):45-50
PubMed ID: 9203532
DOI: 10.1016/s0006-8993(96)01437-0
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3298
Z X Zhang, K Koike, Y Sakamoto, H Jikihara, Y Kanda, K Inoue, K Hirota, A Miyake
Pituitary folliculo-stellate-like cell line produces a cytokine-induced neutrophil chemoattractant
Neuropeptides
1997
31(1):46-51
PubMed ID: 9574837
DOI: 10.1016/s0143-4179(97)90019-6
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3420
Chiaki Koyama, Hirokazu Matsumoto, Takafumi Sakai, Katsumi Wakabayashi, Akihiro Ito, Ernest F. Couch, Kinji Inoue
Pituitary Folliculo-Stellate-Like Cells Stimulate Somatotroic Pituitary Tumor Growth in Nude Mice
Endocr Pathol
1995
6(1):67-75
PubMed ID: 12114691
DOI: 10.1007/BF02914990
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2111
Matsumoto H, Ishibashi Y, Ohtaki T, Hasegawa Y, Koyama C, Inoue K
Newly established murine pituitary folliculo-stellate-like cell line (TtT/GF) secretes potent pituitary glandular cell survival factors, one of which corresponds to metalloproteinase inhibitor.
Biochem Biophys Res Commun
1993
194:909-15
PubMed ID: 8343172
DOI: 10.1006/bbrc.1993.1907
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2112
Matsumoto H, Koyama C, Sawada T, Koike K, Hirota K, Miyake A, Arimura A, Inoue K
Pituitary folliculo-stellate-like cell line (TtT/GF) responds to novel hypophysiotropic peptide (pituitary adenylate cyclase-activating peptide), showing increased adenosine 3',5'-monophosphate and interleukin-6 secretion and cell proliferation.
Endocrinology
1993
133:2150-5
PubMed ID: 8404665
DOI: 10.1210/endo.133.5.8404665
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2110
Inoue K, Matsumoto H, Koyama C, Shibata K, Nakazato Y, Ito A
Establishment of a folliculo-stellate-like cell line from a murine thyrotropic pituitary tumor.
Endocrinology
1992
131:3110-6
PubMed ID: 1446645
DOI: 10.1210/endo.131.6.1446645
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| User's Publication |
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21575
Mitsutani M, Matsushita M, Yokoyama M, Morita A, Hano H, Fujikawa T, Tagami T, Moriyama K.
Growth hormone directly stimulates GATA2 expression.
Growth Horm IGF Res
2024
74:101572
PubMed ID: 38281404
DOI: 10.1016/j.ghir.2024.101572
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11301
Hannen R, Steffani M, Voellger B, Carl B, Wang J, Bartsch JW, Nimsky C.
Effects of anti-estrogens on cell invasion and survival in pituitary adenoma cells: A systematic study.
J. Steroid Biochem. Mol. Biol.
2019
PubMed ID: 30439415
DOI: 10.1016/j.jsbmb.2018.11.005
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12580
Stella Tran, Ying Wang, Pankaj Lamba, Xiang Zhou, Ulrich Boehm, Daniel J Bernard
The CpG island in the murine foxl2 proximal promoter is differentially methylated in primary and immortalized cells
PLoS One
2013
8(10):e76642
PubMed ID: 24098544
DOI: 10.1371/journal.pone.0076642
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12578
Y Kiriyama, H Tsuchiya, T Murakami, K Satoh, Y Tokumitsu
Calcitonin induces IL-6 production via both PKA and PKC pathways in the pituitary folliculo-stellate cell line
Endocrinology
2001
142(8):3563-9
PubMed ID: 11459804
DOI: 10.1210/endo.142.8.8328
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12577
T Katayama, M Nakashima, H Kyan, N Murakami, H Kuroda
A role of pituitary adenylate cyclase activating polypeptide (PACAP) as a regulator of paracrine interactions between folliculo-stellate cells and gonadotropes through the control of activin-follistatin interactions
J Vet Med Sci
2000
62(7):731-6
PubMed ID: 10945291
DOI: 10.1292/jvms.62.731
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