CELL SEARCH SYSTEM -CELL BANK- (RIKEN BRC) [RCB1192 : MDA-MB-453]

4957 Siciliano MJ, Barker PE, Cailleau R. Mutually exclusive genetic signatures of human breast tumor cell lines with a common chromosomal marker. Cancer Res 1979 9(3):919-22 PubMed ID: 427779

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23321 Kumai J, Sasagawa S, Yui Y. Metastatic breast cancer cells adapt to a soft environment with limited involvement of mechanotransduction Exp Cell Res 2025 450(2):114629 PubMed ID: 40466802 DOI: 10.1016/j.yexcr.2025.114629

21684 Masuda Y, Yamashita S, Nakayama Y, Shimizu R, Konishi M. Maitake Beta-Glucan Enhances the Therapeutic Effect of Trastuzumab via Antibody-Dependent Cellular Cytotoxicity and Complement-Dependent Cytotoxicity. Biol Pharm Bull 2024 47(4):840-847 PubMed ID: 38616114 DOI: 10.1248/bpb.b23-00802

21802 Akimoto T, Islam MR, Nagasako A, Kishi K, Nakakaji R, Ohtake M, Hasumi H, Yamaguchi T, Yamada S, Yamamoto T, Ishikawa Y, Umemura M. Alternative magnetic field exposure suppresses tumor growth via metabolic reprogramming. Cancer Sci 2024 PubMed ID: 38877783 DOI: 10.1111/cas.16243

22025 Hong L, Tanaka M, Yasui M, Hara-Chikuma M. HSP90 promotes tumor associated macrophage differentiation during triple-negative breast cancer progression. Sci Rep 2024 14(1):22541 PubMed ID: 39341960 DOI: 10.1038/s41598-024-73394-9

17582 Sugiura S, Yamahira S, Tamura M, Shin K, Shibuta M, Satoh T, Matsuzawa Y, Fujii G, Yanagawa F, Mutoh M, Yanagisawa M, Kato R, Matsui H. Automated cell isolation from photodegradable hydrogel based on fluorescence image analysis Biotechnol Bioeng 2023 Mar 15 PubMed ID: 36919627 DOI: 10.1002/bit.28375

19264 Muguruma M, Asaoka M, Teraoka S, Miyahara K, Kawate T, Ishikawa T. β-Tubulin Isoforms Related to Docetaxel Sensitivity in 2D and 3D Cultured TNBC Cell Lines Anticancer Res 2022 42(10):4735-4742 PubMed ID: 36191981 DOI: 10.21873/anticanres.15978

13416 Sagara M, Miyamoto S, Itoh S, Soda Y, Tani K. Development of New Oncolytic Virotherapy Targeting Breast Cancer Using Coxsackievirus B3. Anticancer Res 2021 PubMed ID: 33419801 DOI: 10.21873/anticanres.14753

20159 Sakabe T, Wakahara M, Shiota G, Umekita Y. Role of cytoplasmic localization of maspin in promoting cell invasion in breast cancer with aggressive phenotype. Sci Rep 2021 11(1):11321 PubMed ID: 34059749 DOI: 10.1038/s41598-021-90887-z

16735 Okada H, Mimura M, Tomita S, Kurita R. Affinity Diversification of a Polymer Probe for Pattern-recognition-based Biosensing Using Chemical Additives Anal Sci 2021 37(5):713-719 PubMed ID: 33518589 DOI: 10.2116/analsci.20SCP23

19447 Wang J, Bhargava P, Yu Y, Sari AN, Zhang H, Ishii N, Yan K, Zhang Z, Ishida Y, Terao K, Kaul SC, Miyako E, Wadhwa R. Novel Caffeic Acid Phenethyl Ester-Mortalin Antibody Nanoparticles Offer Enhanced Selective Cytotoxicity to Cancer Cells Cancers (Basel) 2020 12(9):2370 PubMed ID: 32825706 DOI: 10.3390/cancers12092370

11952 Kimura R, Yoshimaru T, Matsushita Y, Matsuo T, Ono M, Park JH, Sasa M, Miyoshi Y, Nakamura Y, Katagiri T. The GALNT6‑LGALS3BP axis promotes breast cancer cell growth. Int. J. Oncol. 2020 PubMed ID: 31894262 DOI: 10.3892/ijo.2019.4941

12064 Teraoka S, Muguruma M, Takano N, Miyahara K, Kawate T, Kaise H, Yamada K, Miyazawa K, Ishikawa T. Association of BRCA Mutantations and BRCAness Status With Anticancer Drug Sensitivities in Triple-Negative Breast Cancer Cell Lines. J. Surg. Res. 2020 PubMed ID: 32092597 DOI: 10.1016/j.jss.2019.12.040

13226 Muguruma M, Teraoka S, Miyahara K, Ueda A, Asaoka M, Okazaki M, Kawate T, Kuroda M, Miyagi Y, Ishikawa T. Differences in drug sensitivity between two-dimensional and three-dimensional culture systems in triple-negative breast cancer cell lines. Biochem Biophys Res Commun 2020 PubMed ID: 32958246 DOI: 10.1016/j.bbrc.2020.08.075

13770 Kim H, Hoshi M, Iijima M, Kuroda S, Nakamura C. Development of a universal method for the measurement of binding affinities of antibody drugs towards a living cell based on AFM force spectroscopy Anal Methods 2020 12(22):2922-2927 PubMed ID: 32930215 DOI: 10.1039/d0ay00788a

14854 Terasaki A, Kurokawa H, Ito H, Komatsu Y, Matano D, Terasaki M, Bando H, Hara H, Matsui H. Elevated Production of Mitochondrial Reactive Oxygen Species via Hyperthermia Enhanced Cytotoxic Effect of Doxorubicin in Human Breast Cancer Cell Lines MDA-MB-453 and MCF-7 Int J Mol Sci 2020 21(24):9522 PubMed ID: 33333736 DOI: 10.3390/ijms21249522

11360 Futami K, Kimoto M, Lim YWS, Hirao I. Genetic Alphabet Expansion Provides Versatile Specificities and Activities of Unnatural-Base DNA Aptamers Targeting Cancer Cells. Mol Ther Nucleic Acids 2019 PubMed ID: 30594072 DOI: 10.1016/j.omtn.2018.11.011

11511 Behan FM, Iorio F, Picco G, Gonçalves E, Beaver CM, Migliardi G, Santos R, Rao Y, Sassi F, Pinnelli M, Ansari R, Harper S, Jackson DA, McRae R, Pooley R, Wilkinson P, van der Meer D, Dow D, Buser-Doepner C, Bertotti A, Trusolino L, Stronach EA, Saez-Rodriguez J, Yusa K, Garnett MJ. Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens. Nature 2019 PubMed ID: 30971826 DOI: 10.1038/s41586-019-1103-9

11524 Ueda A, Oikawa K, Fujita K, Ishikawa A, Sato E, Ishikawa T, Kuroda M, Kanekura K. Therapeutic potential of PLK1 inhibition in triple-negative breast cancer. Lab. Invest. 2019 PubMed ID: 30996295 DOI: 10.1038/s41374-019-0247-4

11563 Kawase A, Inoue Y, Nakazaki S, Koizumi E, Iwaki M. Radixin knockdown improves the accumulation and efficiency of methotrexate in tumor cells. Oncol. Rep. 2019 PubMed ID: 31115547 DOI: 10.3892/or.2019.7162

14819 Takayama M, Takatsu H, Hamamoto A, Inoue H, Naito T, Nakayama K, Shin HW. The cytoplasmic C-terminal region of the ATP11C variant determines its localization at the polarized plasma membrane J Cell Sci 2019 132(17):jcs231720. PubMed ID: 31371488 DOI: 10.1242/jcs.231720

11228 Ichihara H, Okumura M, Tsujimura K, Matsumoto Y. Theranostics with Hybrid Liposomes in an Orthotopic Graft Model Mice of Breast Cancer. Anticancer Res. 2018 PubMed ID: 30275183 DOI: 10.21873/anticanres.12900

4120 Miyagawa Y, Matsushita Y, Suzuki H, Komatsu M, Yoshimaru T, Kimura R, Yanai A, Honda J, Tangoku A, Sasa M, Miyoshi Y, Katagiri T. Frequent downregulation of LRRC26 by epigenetic alterations is involved in the malignant progression of triple-negative breast cancer. Int. J. Oncol. 2018 PubMed ID: 29512727 DOI: 10.3892/ijo.2018.4301

4288 Khatun A, Shimozawa M, Kito H, Kawaguchi M, Fujimoto M, Ri M, Kajikuri J, Niwa S, Fujii M, Ohya S. Transcriptional Repression and Protein Degradation of the Ca2+-Activated K+ Channel KCa1.1 by Androgen Receptor Inhibition in Human Breast Cancer Cells. Front Physiol 2018 PubMed ID: 29713287 DOI: 10.3389/fphys.2018.00312

4376 Fujimoto M, Kito H, Kajikuri J, Ohya S. Transcriptional repression of human epidermal growth factor receptor 2 by ClC-3 Cl- /H+ transporter inhibition in human breast cancer cells. Cancer Sci. 2018 109(9):2781-2791 PubMed ID: 29949674 DOI: 10.1111/cas.13715

9925 Fujimoto M, Inoue T, Kito H, Niwa S, Suzuki T, Muraki K, Ohya S. Transcriptional repression of HER2 by ANO1 Cl- channel inhibition in human breast cancer cells with resistance to trastuzumab. Biochem. Biophys. Res. Commun. 2017 482:188-194 PubMed ID: 27838298 DOI: 10.1016/j.bbrc.2016.11.033

10445 Yamaguchi H, Ito Y, Miura N, Nagamura Y, Nakabo A, Fukami K, Honda K, Sakai R. Actinin-1 and actinin-4 play essential but distinct roles in invadopodia formation by carcinoma cells. Eur. J. Cell Biol. 2017 96:685-694 PubMed ID: 28797528 DOI: 10.1016/j.ejcb.2017.07.005

5680 Ginting TE, Suryatenggara J, Christian S, Mathew G. Proinflammatory response induced by Newcastle disease virus in tumor and normal cells. Oncolytic Virother 2017 6:21-30 PubMed ID: 28293547 DOI: 10.2147/OV.S123292

14384 Miyasato Y, Shiota T, Ohnishi K, Pan C, Yano H, Horlad H, Yamamoto Y, Yamamoto-Ibusuki M, Iwase H, Takeya M, Komohara Y. High density of CD204-positive macrophages predicts worse clinical prognosis in patients with breast cancer Cancer Sci 2017 108(8):1693-1700 PubMed ID: 28574667 DOI: 10.1111/cas.13287

9818 Kanzaki H, Shinohara F, Suzuki M, Wada S, Miyamoto Y, Yamaguchi Y, Katsumata Y, Makihira S, Kawai T, Taubman MA, Nakamura Y. A-Disintegrin and Metalloproteinase (ADAM) 17 Enzymatically Degrades Interferon-gamma. Sci Rep 2016 6:32259 PubMed ID: 27573075 DOI: 10.1038/srep32259

9880 Poulose AC, Veeranarayanan S, Mohamed MS, Aburto RR, Mitcham T, Bouchard RR, Ajayan PM, Sakamoto Y, Maekawa T, Kumar DS. Multifunctional Cu2-xTe Nanocubes Mediated Combination Therapy for Multi-Drug Resistant MDA MB 453. Sci Rep 2016 6:35961 PubMed ID: 27775048 DOI: 10.1038/srep35961

9992 Khatun A, Fujimoto M, Kito H, Niwa S, Suzuki T, Ohya S. Down-Regulation of Ca2+-Activated K⁺ Channel KCa1.1 in Human Breast Cancer MDA-MB-453 Cells Treated with Vitamin D Receptor Agonists. Int J Mol Sci 2016 17: PubMed ID: 27973439 DOI: 10.3390/ijms17122083

12644 Minatani N, Waraya M, Yamashita K, Kikuchi M, Ushiku H, Kojo K, Ema A, Nishimiya H, Kosaka Y, Katoh H, Sengoku N, Tanino H, Sidransky D, Watanabe M. Prognostic Significance of Promoter DNA Hypermethylation of cysteine dioxygenase 1 (CDO1) Gene in Primary Breast Cancer PLoS One 2016 11(1):e0144862 PubMed ID: 26785325 DOI: 10.1371/journal.pone.0144862

12882 Kikuchi M, Yamashita K, Waraya M, Minatani N, Ushiku H, Kojo K, Ema A, Kosaka Y, Katoh H, Sengoku N, Enomoto T, Tanino H, Sawanobori M, Watanabe M. Epigenetic regulation of ZEB1-RAB25/ESRP1 axis plays a critical role in phenylbutyrate treatment-resistant breast cancer Oncotarget 2016 7(2):1741-53. PubMed ID: 26646320 DOI: 10.18632/oncotarget.6480

7226 Subramanian N, Kanwar JR, Kanwar RK, Krishnakumar S. Targeting Cancer Cells Using LNA-Modified Aptamer-siRNA Chimeras. Nucleic Acid Ther 2015 25:317-22 PubMed ID: 26334953 DOI: 10.1089/nat.2015.0550

7287 Iida R, Ueki M, Yasuda T. Identification of interacting partners of Human Mpv17-like protein with a mitigating effect of mitochondrial dysfunction through mtDNA damage. Free Radic. Biol. Med. 2015 87:336-45 PubMed ID: 26165189 DOI: 10.1016/j.freeradbiomed.2015.07.008

9408 Yasunori Sato, Naoto Sasaki, Megu Saito, Nao Endo, Fumihiko Kugawa, Akemichi Ueno Luteolin Attenuates Doxorubicin-Induced Cytotoxicity to MCF-7 Human Breast Cancer Cells Biol Pharm Bull 2015 38(5):703-9 PubMed ID: 25947916 DOI: 10.1248/bpb.b14-00780

5833 Sato M, Muguruma N, Nakagawa T, Okamoto K, Kimura T, Kitamura S, Yano H, Sannomiya K, Goji T, Miyamoto H, Okahisa T, Mikasa H, Wada S, Iwata M, Takayama T. High antitumor activity of pladienolide B and its derivative in gastric cancer. Cancer Sci 2014 105(1):110-6 PubMed ID: 24635824 DOI: 10.1111/cas.12317

15803 M. Sheikh Mohamed, Srivani Veeranarayanan, Hiroaki Minegishi, Yasushi Sakamoto, Yasuhiro Shimane, Yutaka Nagaoka, Atsushi Aki, Aby Cheruvathoor Poulose, Akinobu Echigo, Yasuhiko Yoshida, Toru Maekawa, D. Sakthi Kumar Cytological and Subcellular Response of Cells Exposed to the Type-1 RIP Curcin and its Hemocompatibility Analysis Scientific Reports 2014 4 DOI: 10.1038/srep05747

17110 Masanari Umemura, Ayako Makino, Itaru Sato, Xianfeng Feng, Kayoko Oda, Makoto Ohtake, Satoshi Izuka, Maki Iwai, Kosuke Matsuo, Haruki Eguchi, Yoshihiro Ishikawa Abstract 5399: A novel treatment for triple-negative breast cancer using intrinsic magnetized paclitaxel Cancer Research 2014 74:5399-5399 DOI: 10.1158/1538-7445.am2014-5399

14401 Yamaguchi Y, Deng D, Sato Y, Hou YT, Watanabe R, Sasaki K, Kawabe M, Hirano E, Morinaga T. Silicate fiber-based 3D cell culture system for anticancer drug screening Anticancer Res 2013 33(12):5301-9 PubMed ID: 24324063

17165 Nakagawa S, Matsuoka Y, Ichihara H, Yoshida H, Yoshida K, Ueoka R. Therapeutic effects of autologous lymphocytes activated with trastuzumab for xenograft mouse models of human breast cancer Biol Pharm Bull 2013 36(5):861-5 PubMed ID: 23649343 DOI: 10.1248/bpb.b12-01084

7842 Takahashi Y, Iwai M, Kawai T, Arakawa A, Ito T, Sakurai-Yageta M, Ito A, Goto A, Saito M, Kasumi F, Murakami Y. Aberrant expression of tumor suppressors CADM1 and 4.1B in invasive lesions of primary breast cancer. Breast Cancer 2012 19:242-52 PubMed ID: 21526423 DOI: 10.1007/s12282-011-0272-7

19336 Ruike Y, Imanaka Y, Sato F, Shimizu K, Tsujimoto G. Genome-wide analysis of aberrant methylation in human breast cancer cells using methyl-DNA immunoprecipitation combined with high-throughput sequencing BMC Genomics 2010 11:137 PubMed ID: 20181289 DOI: 10.1186/1471-2164-11-137

8681 Shinya Shimoda, Hideaki Ichihara, Yoko Matsumoto, Ryuichi Ueoka Nanoparticles of Hybrid Liposomes for the Inhibition of Breast Tumor Growth along with Apoptosis Chemistry Letters 2009 38:134-135 DOI: 10.1246/cl.2009.134

18455 Shimoda S, Ichihara H, Matsumoto Y, Ueoka R. Chemotherapy with hybrid liposomes for human breast tumors along with apoptosis in vivo Int J Pharm 2009 372(1-2):162-8 PubMed ID: 19429276 DOI: 10.1016/j.ijpharm.2009.01.011

18469 Tsuna M, Kageyama S, Fukuoka J, Kitano H, Doki Y, Tezuka H, Yasuda H. Significance of S100A4 as a prognostic marker of lung squamous cell carcinoma Anticancer Res 2009 29(7):2547-54 PubMed ID: 19596927

5877 Yamamoto H, Okumura K, Toshima S, Mukaisho K, Sugihara H, Hattori T, Kato M, Asano S. FXYD3 protein involved in tumor cell proliferation is overproduced in human breast cancer tissues. Biol Pharm Bull 2009 32(7):1148-54 PubMed ID: 19571376 DOI: 10.1248/bpb.32.1148

12771 Azumi K, Ikeda Y, Takeuchi T, Nomura T, Sabau SV, Hamada J, Okada F, Hosokawa M, Yokosawa H. Localization and characterization of γ-glutamyl cyclotransferase in cancer cells Mol Med Rep 2009 2(3):385-91 PubMed ID: 21475839 DOI: 10.3892/mmr_00000110

18925 Hata Y, Etoh T, Inomata M, Shiraishi N, Nishizono A, Kitano S. Efficacy of oncolytic reovirus against human breast cancer cells Oncol Rep 2008 19(6):1395-8 PubMed ID: 18497942

5012 Kawakami T, Chano T, Minami K, Okabe H, Okada Y, Okamoto K. Imprinted DLK1 is a putative tumor suppressor gene and inactivated by epimutation at the region upstream of GTL2 in human renal cell carcinoma. Hum Mol Genet 2006 15(6):821-30 PubMed ID: 16439445 DOI: 10.1093/hmg/ddl001

2763 Ghosh, Mila, Koike, Naoto, Tsunoda, Shin-Ichi, Hirano, Takashi, Kaul, Sunil, Kashiwagi, Hironobu, Kawamoto, Toru, Ohkohchi, Nobuhiro, Saijo, Kaoru, Ohno, Tadao, Miwa, Masanao, Todoroki, Takeshi Characterization and genetic analysis in the newly established human bile duct cancer cell lines. Int J Oncol 2005 26:449-56 PubMed ID: 15645130

3023 Nishikawa, Kazuhiro, Satoh, Haruna, Hirai, Ayako, Suzuzki, Kazuyuki, Asano, Ryuji, Kumadaki, Itsumaro, Hagiwara, Kiyokazu, Yano, Tomohiro alpha-Tocopheryloxybutyric acid enhances necrotic cell death in breast cancer cells treated with chemotherapy agent. Cancer Lett 2003 201:51-6 PubMed ID: 14580686 DOI: 10.1016/s0304-3835(03)00462-2

3040 Satoh H, Nishikawa K, Suzuki K, Asano R, Virgona N, Ichikawa T, Hagiwara K, Yano T. Genistein, a soy isoflavone, enhances necrotic-like cell death in a breast cancer cell treated with a chemotherapeutic agent. Res. Commun. Mol. Pathol. Pharmacol. 2003 113-114:149-58 PubMed ID: 15686114

3019 Akazawa, Akihiko, Nishikawa, Kazuhiro, Suzuki, Kazuyuki, Asano, Ryuji, Kumadaki, Itsumaru, Satoh, Haruna, Hagiwara, Kiyokazu, Shin, Sung Jae, Yano, Tomohiro Induction of apoptosis in a human breast cancer cell overexpressing ErbB-2 receptor by alpha-tocopheryloxybutyric acid. Jpn J Pharmacol 2002 89:417-21 PubMed ID: 12233821 DOI: 10.1254/jjp.89.417

6400 Hatano H, Kawashima H, Ogose A, Hotta T, Endo N. A PCR-ELISA assay for the detection of disseminated osteosarcoma cells in a mouse metastatic model. J Orthop Sci 2001 6(3):269-75 PubMed ID: 11484122 DOI: 10.1007/s007760100046