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Yoshioka D, Nakamura T, Kubota Y, Takekawa M.
Formation of the NLRP3 inflammasome inhibits stress granule assembly by multiple mechanisms
J Biochem
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Jan 31:mvae009
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21574
Kawakami K, Fukuda T, Toyoda M, Nakao Y, Hayashi C, Watanabe Y, Aoki T, Shinjo T, Iwashita M, Yamashita A, Shida M, Sanui T, Uchiumi T, Nishimura F.
Luteolin Is a Potential Immunomodulating Natural Compound against Pulpal Inflammation.
Biomed Res Int
2024
2024:8864513
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21592
Ito F, Yanatori I, Kato K, Toyokuni S.
Protocol for the isolation of GFP-expressing ferroptosis-dependent extracellular vesicles in in vitro cell culture models.
STAR Protoc
2024
5(1):102892
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21650
Matsuo H, Inagami A, Ito Y, Ito N, Iyoda S, Harata Y, Higashitani M, Shoji K, Tanaka M, Noura M, Mikami T, Kato I, Takita J, Nakahata T, Adachi S.
Parbendazole as a promising drug for inducing differentiation of acute myeloid leukemia cells with various subtypes.
Commun Biol
2024
7(1):123
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21651
Tatsuno R, Ichikawa J, Komohara Y, Pan C, Kawasaki T, Enomoto A, Aoki K, Hayakawa K, Iwata S, Jubashi T, Haro H.
Pivotal role of IL-8 derived from the interaction between osteosarcoma and tumor-associated macrophages in osteosarcoma growth and metastasis via the FAK pathway.
Cell Death Dis
2024
15(2):108
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Yamamori Y, Shirai R, Ohkura K, Nagamune H, Tomoyasu T, Tabata A.
Streptolysin S induces proinflammatory cytokine expression in calcium ion-influx-dependent manner.
Curr Res Microb Sci
2024
7:100265
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Washisaka T, Tabata Y.
Live Imaging of Monocyte/Macrophage Differentiation with Cationized Gelatin Nanospheres Incorporating a Molecular Beacon
ACS Biomater Sci Eng
2023
Apr 4
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Murokawa H, Egusa K, Shibutani S, Iwata H.
Mechanistic/mammalian target of rapamycin complex 1 (mTORC1) signaling is involved in phagocytosis activation during THP-1 cell differentiation
J Vet Med Sci
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85(7):772-780
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Yamada M, Nitta Y, Uehara T, Suzuki H, Miya F, Takenouchi T, Tamura M, Ayabe S, Yoshiki A, Maeno A, Saga Y, Furuse T, Yamada I, Okamoto N, Kosaki K, Sugie A.
Heterozygous loss-of-function DHX9 variants are associated with neurodevelopmental disorders: Human genetic and experimental evidences
Eur J Med Genet
2023
66(8):104804
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21116
Komuro R, Honda Y, Yanaizu M, Nagahama M, Kino Y.
Alzheimer's Disease-Associated Alternative Splicing of CD33 Is Regulated by the HNRNPA Family Proteins.
Cells
2023
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Unzai T, Washisaka T, Tabata Y.
An artificial silk elastin-like protein modifies the polarization of human macrophages line THP-1.
J Biomater Appl
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IgG and insulin enhance endocytosis in THP-1 cells via activation of phosphatidylinositol 3-kinase (PI3K).
Biochem Biophys Res Commun
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679:160-166
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21518
Hirata W, Itatani Y, Masui H, Kawada K, Mizuno R, Yamamoto T, Okamoto T, Ogawa R, Inamoto S, Maekawa H, Okamura R, Kiyasu Y, Hanada K, Okamoto M, Nishikawa Y, Sugimoto N, Tamura T, Hatano E, Sakai Y, Obama K.
Downregulation of osteoprotegerin in colorectal cancer cells promotes liver metastasis via activating tumor-associated macrophage.
Sci Rep
2023
13(1):22217
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17691
Ushio S, Wada Y, Nakamura M, Matsumoto D, Hoshika K, Shiromizu S, Iwata N, Esumi S, Kajizono M, Kitamura Y, Sendo T.
Anxiolytic-like effects of hochuekkito in lipopolysaccharide-treated mice involve interleukin-6 inhibition
Front Pharmacol
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Kasai F, Hirayama N, Fukushima M, Kohara A, Nakamura Y.
THP-1 reference data: proposal of an in vitro branched evolution model for cancer cell lines.
Int J Cancer
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PubMed ID: 35373342
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Ikegami H, Yamasaki K, Ogawa M, Nemoto K, Akata K, Noguchi S, Fukuda K, Kawanami T, Mukae H, Yatera K.
Reduced phagocytic activity of human alveolar macrophages infected with Mycobacterium avium complex
J Infect Chemother
2022
Aug 1
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Kawase A, Takashima O, Tanaka S, Shimada H, Iwaki M.
Diclofenac-Induced Cytotoxicity in Direct and Indirect Co-Culture of HepG2 Cells with Differentiated THP-1 Cells
Int J Mol Sci
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Tabata A, Matsumoto A, Fujimoto A, Ohkura K, Ikeda T, Oda H, Yokohata S, Kobayashi M, Tomoyasu T, Takao A, Ohkuni H, Nagamune H.
Dual functions of discoidinolysin, a cholesterol-dependent cytolysin with N-terminal discoidin domain produced from Streptococcus mitis strain Nm-76.
J Oral Microbiol
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Ito M, Maejima Y, Nishimura K, Nakae Y, Ono A, Iwaki-Egawa S.
A role for N-glycosylation in active adenosine deaminase 2 production.
Biochim Biophys Acta Gen Subj
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Yokohata S, Ohkura K, Nagamune H, Tomoyasu T, Tabata A.
Human serum albumin stabilizes streptolysin S activity secreted in the extracellular milieu by streptolysin S-producing streptococci.
Microbiol Immunol
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Kanai R, Nakashima A, Doi S, Kimura T, Yoshida K, Maeda S, Ishiuchi N, Yamada Y, Ike T, Doi T, Kato Y, Masaki T.
Interferon-γ enhances the therapeutic effect of mesenchymal stem cells on experimental renal fibrosis.
Sci Rep
2021
PubMed ID: 33441701
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Nakatani K, Matsuo H, Harata Y, Higashitani M, Koyama A, Noura M, Nishinaka-Arai Y, Kamikubo Y, Adachi S.
Inhibition of CDK4/6 and autophagy synergistically induces apoptosis in t(8;21) acute myeloid leukemia cells.
Int J Hematol
2021
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Fujita M, Yamamoto H, Yoshida N, Ono R, Matsuoka T, Kihara S.
Atheroprotective Roles of Adiponectin via CCL2 Inhibition.
J Atheroscler Thromb
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28(11):1204-1213
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Li H, Somiya M, Kuroda S.
Enhancing antibody-dependent cellular phagocytosis by Re-education of tumor-associated macrophages with resiquimod-encapsulated liposomes.
Biomaterials
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Itoh K, Shigemi H, Chihara K, Sada K, Yamauchi T, Iwasaki H.
Caspofungin suppresses zymosan-induced cytokine and chemokine release in THP-1 cells: possible involvement of the spleen tyrosine kinase pathway
Transl Res
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227:53-63
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Tomita T, Kato M, Mishima T, Matsunaga Y, Sanjo H, Ito KI, Minagawa K, Matsui T, Oikawa H, Takahashi S, Takao T, Iwai N, Mino T, Takeuchi O, Maru Y, Hiratsuka S.
Extracellular mRNA transported to the nucleus exerts translation-independent function.
Nat Commun
2021
12(1):3655
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Kawakatsu K, Maemura M, Seta Y, Nishikata T.
Involvement of Annexin A2 in Serum-MAF Dependent Phagocytic Activation of Macrophages.
Anticancer Res
2021
41(8):4089-4092
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Minoru Sasaki, Yu Shimoyama, Yoshitoyo Kodama, Taichi Ishikawa
Abiotrophia defectiva DnaK Promotes Fibronectin-Mediated Adherence to HUVECs and Induces a Proinflammatory Response
International Journal of Molecular Sciences
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Lee S, Ishitsuka A, Kuroki T, Lin YH, Shibuya A, Hongu T, Funakoshi Y, Kanaho Y, Nagata K, Kawaguchi A.
Arf6 exacerbates allergic asthma through cell-to-cell transmission of ASC inflammasomes
JCI Insight
2021
6(16):e139190
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Kato S, Arasaki K, Tokutomi N, Imai Y, Inoshita T, Hattori N, Sasaki T, Sato M, Wakana Y, Inoue H, Tagaya M.
Syntaxin 17, an ancient SNARE paralog, plays different and conserved roles in different organisms.
J Cell Sci
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PubMed ID: 34704591
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Sakamaki I, Fukushi M, Ohashi W, Tanaka Y, Itoh K, Tomihara K, Yamamoto Y, Iwasaki H.
Sitafloxacin reduces tumor necrosis factor alpha (TNFα) converting enzyme (TACE) phosphorylation and activity to inhibit TNFα release from lipopolysaccharide-stimulated THP-1 cells.
Sci Rep
2021
11(1):24154
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Ito F, Kato K, Yanatori I, Murohara T, Toyokuni S.
Ferroptosis-dependent extracellular vesicles from macrophage contribute to asbestos-induced mesothelial carcinogenesis through loading ferritin.
Redox Biol
2021
47:102174
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Sasaki M, Shimoyama Y, Kodama Y, Ishikawa T.
Tryptophanyl tRNA Synthetase from Human Macrophages Infected by Porphyromonas gingivalis Induces a Proinflammatory Response Associated with Atherosclerosis.
Pathogens
2021
10(12)
PubMed ID: 34959604
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10948
Karen Yotsumoto, Terukazu Sanui, Urara Tanaka, Hiroaki Yamato, Rehab Alshargabi, Takanori Shinjo, Yuki Nakao, Yukari Watanabe, Chikako Hayashi, Takaharu Taketomi, Takao Fukuda, Fusanori Nishimura
Amelogenin Downregulates Interferon Gamma-Induced Major Histocompatibility Complex Class II Expression Through Suppression of Euchromatin Formation in the Class II Transactivator Promoter IV Region in Macrophages
Front Immunol
2020
11:709
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10952
Seiichi Sato, Kai Li, Nozomi Sakurai, Mei Hashizume, Sunanda Baidya, Hirotaka Nonaka, Koki Noguchi, Kozo Ishikawa, Chikashi Obuse, Akinori Takaoka
Regulation of an adaptor protein STING by Hsp90β to enhance innate immune responses against microbial infections
Cell Immunol
2020
356:104188
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12599
Kobayashi N, Oda T, Takizawa M, Ishizaki T, Tsukamoto N, Yokohama A, Takei H, Saitoh T, Shimizu H, Honma K, Kimura-Masuda K, Kuroda Y, Ishihara R, Murakami Y, Murakami H, Handa H.
Integrin α7 and Extracellular Matrix Laminin 211 Interaction Promotes Proliferation of Acute Myeloid Leukemia Cells and Is Associated with Granulocytic Sarcoma
Cancers (Basel)
2020
12(2):363
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Matsushita M, Nakamura T, Moriizumi H, Miki H, Takekawa M.
Stress-responsive MTK1 SAPKKK serves as a redox sensor that mediates delayed and sustained activation of SAPKs by oxidative stress.
Sci Adv
2020
PubMed ID: 32637591
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Tabata A, Ohkuni H, Hino H, Saigo T, Kodama C, Tang Q, Tomoyasu T, Fukunaga Y, Itoh Y, Nagamune H.
Cytotoxic property of Streptococcus mitis strain producing two different types of cholesterol-dependent cytolysins.
Infect Genet Evol
2020
PubMed ID: 32731044
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Akamatsu M, Mashiba R, Kawakatsu K, Ishikawa M, Nishikata T.
Comparison of Macrophage Activation Using γ-Globulin and Serum-derived Macrophage Activating Factor.
Anticancer Res
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PubMed ID: 32727796
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Yanaizu M, Washizu C, Nukina N, Satoh JI, Kino Y.
CELF2 regulates the species-specific alternative splicing of TREM2.
Sci Rep
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PubMed ID: 33093587
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Noura M, Morita K, Kiyose H, Matsuo H, Nishinaka-Arai Y, Kurokawa M, Kamikubo Y, Adachi S.
Pivotal role of DPYSL2A in KLF4-mediated monocytic differentiation of acute myeloid leukemia cells.
Sci Rep
2020
PubMed ID: 33219287
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Hideo Kataoka, Ayumi Saeki, Akira Hasebe, Ken-ichiro Shibata, Takeshi Into
Naringenin suppresses Toll-like receptor 2-mediated inflammatory responses through inhibition of receptor clustering on lipid rafts
Food Sci Nutr
2020
PubMed ID: 33598179
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4052
Kidoya H, Muramatsu F, Shimamura T, Jia W, Satoh T, Hayashi Y, Naito H, Kunisaki Y, Arai F, Seki M, Suzuki Y, Osawa T, Akira S, Takakura N.
Regnase-1-mediated post-transcriptional regulation is essential for hematopoietic stem and progenitor cell homeostasis
Nat Commun
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Suzuki S, Fukuda T, Nagayasu S, Nakanishi J, Yoshida K, Hirata-Tsuchiya S, Nakao Y, Sano T, Yamashita A, Yamada S, Ohta K, Shiba H, Nishimura F.
Dental pulp cell-derived powerful inducer of TNF-α comprises PKR containing stress granule rich microvesicles.
Sci Rep
2019
PubMed ID: 30846715
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Tabata A, Yamada T, Ohtani H, Ohkura K, Tomoyasu T, Nagamune H.
β-Hemolytic Streptococcus anginosus subsp. anginosus causes streptolysin S-dependent cytotoxicity to human cell culture lines in vitro.
J Oral Microbiol
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Minato KI, Laan LC, van Die I, Mizuno M.
Pleurotus citrinopileatus polysaccharide stimulates anti-inflammatory properties during monocyte-to-macrophage differentiation.
Int J Biol Macromol
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Yamamoto M, Matsumura R, Hirata Y, Nagamune H.
A comparative study of skin irritation caused by novel bis-quaternary ammonium compounds and commonly used antiseptics by using cell culture methods.
Toxicol In Vitro
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54:75-81
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Tsubasa Koga, Keiko Morotomi-Yano, Takashi Sakugawa, Hisato Saitoh, Ken-Ichi Yano
Nanosecond pulsed electric fields induce extracellular release of chromosomal DNA and histone citrullination in neutrophil-differentiated HL-60 cells
Sci Rep
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9(1):8451
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Iwashima T, Kudome Y, Kishimoto Y, Saita E, Tanaka M, Taguchi C, Hirakawa S, Mitani N, Kondo K, Iida K.
Aronia berry extract inhibits TNF-α-induced vascular endothelial inflammation through the regulation of STAT3
Food Nutr Res
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Li F, Kitajima S, Kohno S, Yoshida A, Tange S, Sasaki S, Okada N, Nishimoto Y, Muranaka H, Nagatani N, Suzuki M, Masuda S, Thai TC, Nishiuchi T, Tanaka T, Barbie DA, Mukaida N, Takahashi C.
Retinoblastoma Inactivation Induces a Protumoral Microenvironment via Enhanced CCL2 Secretion
Cancer Res
2019
79(15):3903-3915
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Horiguchi Y, Ohta N, Yamamoto S, Koide M, Fujino Y.
Midazolam suppresses the lipopolysaccharide-stimulated immune responses of human macrophages via translocator protein signaling
Int Immunopharmacol
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Giriwono PE, Shirakawa H, Ohsaki Y, Sato S, Aoyama Y, Ho HJ, Goto T, Komai M.
Geranylgeraniol Suppresses the Expression of IRAK1 and TRAF6 to Inhibit NFκB Activation in Lipopolysaccharide-Induced Inflammatory Responses in Human Macrophage-Like Cells
Int J Mol Sci
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Yamazoe H.
Multifunctional protein microparticles for medical applications.
Biomaterials
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Sumide K, Matsuoka Y, Kawamura H, Nakatsuka R, Fujioka T, Asano H, Takihara Y, Sonoda Y.
A revised road map for the commitment of human cord blood CD34-negative hematopoietic stem cells.
Nat Commun
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Identification of novel Legionella genes required for endosymbiosis in Paramecium based on comparative genome analysis with Holospora spp.
FEMS Microbiol. Ecol.
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Zhitnyuk Y, Gee P, Lung MSY, Sasakawa N, Xu H, Saito H, Hotta A.
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Segawa S, Kondo Y, Nakai Y, Iizuka A, Kaneko S, Yokosawa M, Furuyama K, Tsuboi H, Goto D, Matsumoto I, Sumida T.
Placenta Specific 8 Suppresses IL-18 Production through Regulation of Autophagy and Is Associated with Adult Still Disease.
J. Immunol.
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Pneumococcal DNA-binding proteins released through autolysis induce the production of proinflammatory cytokines via toll-like receptor 4.
Cell. Immunol.
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Int J Mol Sci
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Mashiba R, Ishikawa M, Sumiya YU, Kawakatsu K, Tran NK, Nishikata T.
Phagocytic Activation of Macrophages with Serum MAF Depends on Engulfment Efficiency and Not Migratory Activity.
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Fukatsu H, Koide N, Tada-Oikawa S, Izuoka K, Ikegami A, Ichihara S, Ukaji T, Morita N, Naiki Y, Komatsu T, Umezawa K.
NF‑κB inhibitor DHMEQ inhibits titanium dioxide nanoparticle‑induced interleukin‑1β production: Inhibition of the PM2.5‑induced inflammation model.
Mol Med Rep
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Komoda H, Shiraki A, Oyama JI, Nishikido T, Node K.
Azelnidipine Inhibits the Differentiation and Activation of THP-1 Macrophages through the L-Type Calcium Channel.
J. Atheroscler. Thromb.
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Ebe H, Matsumoto I, Kawaguchi H, Kurata I, Tanaka Y, Inoue A, Kondo Y, Tsuboi H, Sumida T.
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Clin. Exp. Immunol.
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Yoshida K, Nakashima A, Doi S, Ueno T, Okubo T, Kawano KI, Kanawa M, Kato Y, Higashi Y, Masaki T.
Serum-Free Medium Enhances the Immunosuppressive and Antifibrotic Abilities of Mesenchymal Stem Cells Utilized in Experimental Renal Fibrosis.
Stem Cells Transl Med
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Mol Med Rep
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Ken-ichiro Minato, Akihiro Ohara, and Masashi Mizuno
A Proinflammatory Effect of the β-Glucan from Pleurotus cornucopiae Mushroom on Macrophage Action
Mediators of Inflammation
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Arasaki K, Mikami Y, Shames SR, Inoue H, Wakana Y, Tagaya M.
Legionella effector Lpg1137 shuts down ER-mitochondria communication through cleavage of syntaxin 17.
Nat Commun
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Masataka Oda, Hisanori Domon, Mie Kurosawa, Toshihito Isono, Tomoki Maekawa, Masaya Yamaguchi, Shigetada Kawabata, Yutaka Terao
Streptococcus pyogenes Phospholipase A 2 Induces the Expression of Adhesion Molecules on Human Umbilical Vein Endothelial Cells and Aorta of Mice
Front Cell Infect Microbiol
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